4Y05A

Kif2c short loop2 construct
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
356
structure length
330
Chain Sequence
FPNWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSKCLLLVHEKVDYLENQAFCFDFAFDETASNEVVYRFTAAPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDLSKGIYAMASADVFLLKNQPCYRKLGLEVYVTFFEIYNGKLFDLLNKKAKLRVLEDGKQQVQVVGLQEHLVNSADDVIKMIDMGSACRTNSSRSHACFQIILRAKGRMHGKFSLVDLAGNERRMEGAEINKSLLALKECIRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIATISPGISSCEYTLNTLRYADRVKEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title New Insights into the Coupling between Microtubule Depolymerization and ATP Hydrolysis by Kinesin-13 Protein Kif2C.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords Kinesin-like protein KIF2C
total genus 106
structure length 330
sequence length 356
ec nomenclature
pdb deposition date 2015-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 4y05A00
4PFPA 1I6IA 1VFZA 2G1QA 1V8KA 1G8XA 1MKJA 4ZHIA 1BG2A 2GRYA 4A1ZA 4BN2A 1V8JA 1II6A 2FKYA 4ANJA 3X2TA 1X88A 2X2RA 4FRZA 1N6MA 3DC4A 1VOMA 1FMWA 4DBRA 3WPNA 1F9UA 2X7CA 3CJOA 4BXNA 3K3BA 3ZCWA 2KINA 3KENA 4DBQA 1YRSA 4GKRA 3U06A 3GBJA 2OWMA 1T5CA 1MMAA 1MMDA 3ZFCA 1F9WA 2ZFLA 4A28A 1D1CA 4E7ZA 3KINA 4AP0A 1BR1A 3L9HA 2VASA 1BR2A 3BFNA 1RY6A 2FL6A 2ZFKA 4AS7A 1D0XA 2ZFMA 2PG2A 4ZCAA 3HQDA 4PFOA 2X7EA 3K5EA 4B7BA 4E7SA 5LT1A 2NCDA 3KARA 2UYIA 2WOGA 1I5SA 4A5YA 4ETPA 3ZFDA 3CNZA 1FMVA 2MYSA 2VB6A 2X7DA 3B6UA 4PJJA 2Y65A 1GOJA 1D1BA 2XAEA 5HLEA 3H4SA 5GSZA 2XT3A 2IEHA 3COBA 4A14A 4PJLA 4UBFA 3B6VA 4LNUK 2VVGA 1Q0BA 2FL2A 1VFVA 2X51A 4PJNA 5LT3A 1MMGA 2V26A 1LVKA 1F9TA 2FMEA 4A50A 1KK7A 4BBGA 2ZFIA 2HEHA 5LT2A 1D1AA 3L1CA 1LKXA 2ZFJA 3NWNA 1SDMA 2Q2YA 3LREA 5LT0A 3PXNA 1D0YA 1D0ZA 1MNEA 2Y5WA 3T0QA 1F9VA 4HNAK 4PK4A 5LT4A 1VFXA 3DCBA 4A51A 1CZ7A 3WRDA 1BR4A 4PJMA 1VFWA 4Y05A 4H1GA 2Q2ZA 1MMNA 2GM1A 2UYMA
chains in the Genus database with same CATH superfamily
4PFPA 1I6IA 1VFZA 2G1QA 1V8KA 1G8XA 1MKJA 4ZHIA 1BG2A 2GRYA 4A1ZA 4BN2A 1V8JA 1II6A 2FKYA 4ANJA 3X2TA 1X88A 2X2RA 4FRZA 4GKPA 1N6MA 3DC4A 1VOMA 1FMWA 4DBRA 3WPNA 1F9UA 2X7CA 3CJOA 4BXNA 3K3BA 3ZCWA 2KINA 3KENA 4DBQA 1YRSA 4GKRA 3U06A 3GBJA 2OWMA 1T5CA 1MMAA 1MMDA 3ZFCA 1F9WA 2ZFLA 4A28A 1D1CA 4E7ZA 3KINA 4GKQA 4AP0A 1BR1A 3L9HA 2VASA 1BR2A 3BFNA 1RY6A 2FL6A 2ZFKA 4AS7A 1D0XA 2ZFMA 2PG2A 4ZCAA 3HQDA 4PFOA 2X7EA 3K5EA 4B7BA 4E7SA 5LT1A 2NCDA 3KARA 2UYIA 2O0AA 2WOGA 1I5SA 4A5YA 4ETPA 3ZFDA 3CNZA 1FMVA 2MYSA 2VB6A 2X7DA 3B6UA 4PJJA 2Y65A 1GOJA 1D1BA 2XAEA 5HLEA 3H4SA 5GSZA 2XT3A 2IEHA 3COBA 4A14A 4PJLA 4UBFA 3B6VA 4LNUK 2VVGA 1Q0BA 2FL2A 1VFVA 2X51A 4PJNA 5LT3A 1MMGA 2V26A 1LVKA 1F9TA 2FMEA 4A50A 1KK7A 4BBGA 2ZFIA 2HEHA 5LT2A 1D1AA 3L1CA 1LKXA 2ZFJA 4ETPB 3NWNA 1SDMA 2Q2YA 3LREA 5LT0A 3PXNA 1D0YA 1D0ZA 1MNEA 2Y5WA 3T0QA 1F9VA 4HNAK 4PK4A 5LT4A 1VFXA 3DCBA 4A51A 1CZ7A 3WRDA 1BR4A 4PJMA 1VFWA 4Y05A 4H1GA 2Q2ZA 1MMNA 2GM1A 2UYMA
chains in the Genus database with same CATH topology
4PFPA 1I6IA 1VFZA 2G1QA 1V8KA 1G8XA 1MKJA 4ZHIA 1BG2A 2GRYA 4A1ZA 4BN2A 1V8JA 1II6A 2FKYA 4ANJA 3X2TA 1X88A 2X2RA 4FRZA 1N6MA 3DC4A 1VOMA 1FMWA 4DBRA 3WPNA 1F9UA 2X7CA 3CJOA 4BXNA 3K3BA 3ZCWA 2KINA 3KENA 4DBQA 1YRSA 4GKRA 3U06A 3GBJA 2OWMA 1T5CA 1MMAA 1MMDA 3ZFCA 1F9WA 2ZFLA 4A28A 1D1CA 4E7ZA 3KINA 4AP0A 1BR1A 3L9HA 2VASA 1BR2A 3BFNA 1RY6A 2FL6A 2ZFKA 4AS7A 1D0XA 2ZFMA 2PG2A 4ZCAA 3HQDA 4PFOA 2X7EA 3K5EA 4B7BA 4E7SA 5LT1A 2NCDA 3KARA 2UYIA 2WOGA 1I5SA 4A5YA 4ETPA 3ZFDA 3CNZA 1FMVA 2MYSA 2VB6A 2X7DA 3B6UA 4PJJA 2Y65A 1GOJA 1D1BA 2XAEA 5HLEA 3H4SA 5GSZA 2XT3A 2IEHA 3COBA 4A14A 4PJLA 4UBFA 3B6VA 4LNUK 2VVGA 1Q0BA 2FL2A 1VFVA 2X51A 4PJNA 5LT3A 1MMGA 2V26A 1LVKA 1F9TA 2FMEA 4A50A 1KK7A 4BBGA 2ZFIA 2HEHA 5LT2A 1D1AA 3L1CA 1LKXA 2ZFJA 3NWNA 1SDMA 2Q2YA 3LREA 5LT0A 3PXNA 1D0YA 1D0ZA 1MNEA 2Y5WA 3T0QA 1F9VA 4HNAK 4PK4A 5LT4A 1VFXA 3DCBA 4A51A 1CZ7A 3WRDA 1BR4A 4PJMA 1VFWA 4Y05A 4H1GA 2Q2ZA 1MMNA 2GM1A 2UYMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PFP A;  1I6I A;  1VFZ A;  2G1Q A;  1V8K A;  1G8X A;  1MKJ A;  4ZHI A;  1BG2 A;  2GRY A;  4A1Z A;  4BN2 A;  1V8J A;  1II6 A;  2FKY A;  4ANJ A;  3X2T A;  1X88 A;  2X2R A;  4FRZ A;  1N6M A;  3DC4 A;  1VOM A;  1FMW A;  4DBR A;  3WPN A;  1F9U A;  2X7C A;  3CJO A;  4BXN A;  3K3B A;  3ZCW A;  2KIN A;  3KEN A;  4DBQ A;  1YRS A;  4GKR A;  3U06 A;  3GBJ A;  2OWM A;  1T5C A;  1MMA A;  1MMD A;  3ZFC A;  1F9W A;  2ZFL A;  4A28 A;  1D1C A;  4E7Z A;  3KIN A;  4AP0 A;  1BR1 A;  3L9H A;  2VAS A;  1BR2 A;  3BFN A;  1RY6 A;  2FL6 A;  2ZFK A;  4AS7 A;  1D0X A;  2ZFM A;  2PG2 A;  4ZCA A;  3HQD A;  4PFO A;  2X7E A;  3K5E A;  4B7B A;  4E7S A;  5LT1 A;  2NCD A;  3KAR A;  2UYI A;  2WOG A;  1I5S A;  4A5Y A;  4ETP A;  3ZFD A;  3CNZ A;  1FMV A;  2MYS A;  2VB6 A;  2X7D A;  3B6U A;  4PJJ A;  2Y65 A;  1GOJ A;  1D1B A;  2XAE A;  5HLE A;  3H4S A;  5GSZ A;  2XT3 A;  2IEH A;  3COB A;  4A14 A;  4PJL A;  4UBF A;  3B6V A;  4LNU K;  2VVG A;  1Q0B A;  2FL2 A;  1VFV A;  2X51 A;  4PJN A;  5LT3 A;  1MMG A;  2V26 A;  1LVK A;  1F9T A;  2FME A;  4A50 A;  1KK7 A;  4BBG A;  2ZFI A;  2HEH A;  5LT2 A;  1D1A A;  3L1C A;  1LKX A;  2ZFJ A;  3NWN A;  1SDM A;  2Q2Y A;  3LRE A;  5LT0 A;  3PXN A;  1D0Y A;  1D0Z A;  1MNE A;  2Y5W A;  3T0Q A;  1F9V A;  4HNA K;  4PK4 A;  5LT4 A;  1VFX A;  3DCB A;  4A51 A;  1CZ7 A;  3WRD A;  1BR4 A;  4PJM A;  1VFW A;  4Y05 A;  4H1G A;  2Q2Z A;  1MMN A;  2GM1 A;  2UYM A; 
#chains in the Genus database with same CATH topology
 4PFP A;  1I6I A;  1VFZ A;  2G1Q A;  1V8K A;  1G8X A;  1MKJ A;  4ZHI A;  1BG2 A;  2GRY A;  4A1Z A;  4BN2 A;  1V8J A;  1II6 A;  2FKY A;  4ANJ A;  3X2T A;  1X88 A;  2X2R A;  4FRZ A;  4GKP A;  1N6M A;  3DC4 A;  1VOM A;  1FMW A;  4DBR A;  3WPN A;  1F9U A;  2X7C A;  3CJO A;  4BXN A;  3K3B A;  3ZCW A;  2KIN A;  3KEN A;  4DBQ A;  1YRS A;  4GKR A;  3U06 A;  3GBJ A;  2OWM A;  1T5C A;  1MMA A;  1MMD A;  3ZFC A;  1F9W A;  2ZFL A;  4A28 A;  1D1C A;  4E7Z A;  3KIN A;  4GKQ A;  4AP0 A;  1BR1 A;  3L9H A;  2VAS A;  1BR2 A;  3BFN A;  1RY6 A;  2FL6 A;  2ZFK A;  4AS7 A;  1D0X A;  2ZFM A;  2PG2 A;  4ZCA A;  3HQD A;  4PFO A;  2X7E A;  3K5E A;  4B7B A;  4E7S A;  5LT1 A;  2NCD A;  3KAR A;  2UYI A;  2O0A A;  2WOG A;  1I5S A;  4A5Y A;  4ETP A;  3ZFD A;  3CNZ A;  1FMV A;  2MYS A;  2VB6 A;  2X7D A;  3B6U A;  4PJJ A;  2Y65 A;  1GOJ A;  1D1B A;  2XAE A;  5HLE A;  3H4S A;  5GSZ A;  2XT3 A;  2IEH A;  3COB A;  4A14 A;  4PJL A;  4UBF A;  3B6V A;  4LNU K;  2VVG A;  1Q0B A;  2FL2 A;  1VFV A;  2X51 A;  4PJN A;  5LT3 A;  1MMG A;  2V26 A;  1LVK A;  1F9T A;  2FME A;  4A50 A;  1KK7 A;  4BBG A;  2ZFI A;  2HEH A;  5LT2 A;  1D1A A;  3L1C A;  1LKX A;  2ZFJ A;  4ETP B;  3NWN A;  1SDM A;  2Q2Y A;  3LRE A;  5LT0 A;  3PXN A;  1D0Y A;  1D0Z A;  1MNE A;  2Y5W A;  3T0Q A;  1F9V A;  4HNA K;  4PK4 A;  5LT4 A;  1VFX A;  3DCB A;  4A51 A;  1CZ7 A;  3WRD A;  1BR4 A;  4PJM A;  1VFW A;  4Y05 A;  4H1G A;  2Q2Z A;  1MMN A;  2GM1 A;  2UYM A; 
#chains in the Genus database with same CATH homology
 4PFP A;  1I6I A;  1VFZ A;  2G1Q A;  1V8K A;  1G8X A;  1MKJ A;  4ZHI A;  1BG2 A;  2GRY A;  4A1Z A;  4BN2 A;  1V8J A;  1II6 A;  2FKY A;  4ANJ A;  3X2T A;  1X88 A;  2X2R A;  4FRZ A;  1N6M A;  3DC4 A;  1VOM A;  1FMW A;  4DBR A;  3WPN A;  1F9U A;  2X7C A;  3CJO A;  4BXN A;  3K3B A;  3ZCW A;  2KIN A;  3KEN A;  4DBQ A;  1YRS A;  4GKR A;  3U06 A;  3GBJ A;  2OWM A;  1T5C A;  1MMA A;  1MMD A;  3ZFC A;  1F9W A;  2ZFL A;  4A28 A;  1D1C A;  4E7Z A;  3KIN A;  4AP0 A;  1BR1 A;  3L9H A;  2VAS A;  1BR2 A;  3BFN A;  1RY6 A;  2FL6 A;  2ZFK A;  4AS7 A;  1D0X A;  2ZFM A;  2PG2 A;  4ZCA A;  3HQD A;  4PFO A;  2X7E A;  3K5E A;  4B7B A;  4E7S A;  5LT1 A;  2NCD A;  3KAR A;  2UYI A;  2WOG A;  1I5S A;  4A5Y A;  4ETP A;  3ZFD A;  3CNZ A;  1FMV A;  2MYS A;  2VB6 A;  2X7D A;  3B6U A;  4PJJ A;  2Y65 A;  1GOJ A;  1D1B A;  2XAE A;  5HLE A;  3H4S A;  5GSZ A;  2XT3 A;  2IEH A;  3COB A;  4A14 A;  4PJL A;  4UBF A;  3B6V A;  4LNU K;  2VVG A;  1Q0B A;  2FL2 A;  1VFV A;  2X51 A;  4PJN A;  5LT3 A;  1MMG A;  2V26 A;  1LVK A;  1F9T A;  2FME A;  4A50 A;  1KK7 A;  4BBG A;  2ZFI A;  2HEH A;  5LT2 A;  1D1A A;  3L1C A;  1LKX A;  2ZFJ A;  3NWN A;  1SDM A;  2Q2Y A;  3LRE A;  5LT0 A;  3PXN A;  1D0Y A;  1D0Z A;  1MNE A;  2Y5W A;  3T0Q A;  1F9V A;  4HNA K;  4PK4 A;  5LT4 A;  1VFX A;  3DCB A;  4A51 A;  1CZ7 A;  3WRD A;  1BR4 A;  4PJM A;  1VFW A;  4Y05 A;  4H1G A;  2Q2Z A;  1MMN A;  2GM1 A;  2UYM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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