3WRDA

Crystal structure of the kif5c motor domain without any nucleotide
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
330
structure length
310
Chain Sequence
AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKKSLSALGNVISALAEKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding
pubmed doi rcsb
molecule tags Motor protein
source organism Mus musculus
molecule keywords Kinesin heavy chain isoform 5C
total genus 77
structure length 310
sequence length 330
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-02-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 3wrdA00
1SDMA 3U06A 1GOJA 3PXNA 3L1CA 1FMWA 1VFXA 4A50A 2VASA 5LT0A 4FRZA 4DBRA 1I5SA 4ANJA 3WRDA 1VOMA 4PJNA 1Q0BA 1BR1A 4BN2A 3L9HA 4A51A 1CZ7A 2IEHA 1MNEA 1BR2A 1F9VA 2Q2ZA 3DC4A 3KINA 2ZFIA 4HNAK 4ZCAA 1F9WA 4LNUK 1RY6A 4ZHIA 4UBFA 1BR4A 2WOGA 1F9TA 2NCDA 4B7BA 3HQDA 1BG2A 1II6A 2Q2YA 4PFPA 4ETPA 2ZFKA 2FL2A 1N6MA 2UYIA 2Y65A 2GM1A 1D1AA 4Y05A 1LKXA 1T5CA 1VFWA 3CNZA 4DBQA 2Y5WA 3BFNA 2KINA 1D1BA 1VFZA 4PK4A 1I6IA 1V8KA 3B6VA 3WPNA 3DCBA 1MKJA 4H1GA 4A14A 3ZFCA 1MMGA 4PJLA 4BBGA 3GBJA 2X7DA 4PJMA 2OWMA 5LT2A 5LT1A 1D0XA 4PFOA 2ZFLA 2MYSA 3KENA 1KK7A 1F9UA 1MMAA 3H4SA 4A1ZA 3T0QA 3KARA 1D0YA 2PG2A 2XT3A 2X2RA 1X88A 2FMEA 1VFVA 2XAEA 3ZFDA 2X7CA 2UYMA 5LT3A 4A5YA 3CJOA 2X7EA 1FMVA 4E7SA 2VB6A 1D0ZA 4GKRA 4BXNA 2HEHA 4A28A 3K5EA 3NWNA 3COBA 3K3BA 1G8XA 3ZCWA 2FL6A 1YRSA 2ZFJA 5GSZA 4E7ZA 2VVGA 1D1CA 2X51A 3LREA 3B6UA 4PJJA 1MMNA 2ZFMA 1LVKA 4AP0A 1V8JA 2V26A 1MMDA 2FKYA 3X2TA 4AS7A 5LT4A 5HLEA 2GRYA 2G1QA
chains in the Genus database with same CATH superfamily
1SDMA 3U06A 1GOJA 3PXNA 3L1CA 1FMWA 1VFXA 4A50A 2VASA 5LT0A 4FRZA 4DBRA 1I5SA 4ANJA 3WRDA 1VOMA 4PJNA 1Q0BA 1BR1A 4BN2A 3L9HA 4A51A 1CZ7A 2IEHA 1MNEA 1BR2A 1F9VA 2Q2ZA 3DC4A 3KINA 2ZFIA 4HNAK 4ZCAA 1F9WA 4LNUK 1RY6A 4ZHIA 4GKPA 4UBFA 1BR4A 2WOGA 1F9TA 2NCDA 4B7BA 3HQDA 1BG2A 1II6A 2Q2YA 4PFPA 4ETPA 2ZFKA 2FL2A 1N6MA 2UYIA 2Y65A 2GM1A 1D1AA 4Y05A 1LKXA 1T5CA 1VFWA 3CNZA 4DBQA 2Y5WA 3BFNA 2KINA 1D1BA 1VFZA 4PK4A 1I6IA 1V8KA 3B6VA 3WPNA 3DCBA 1MKJA 2O0AA 4GKQA 4H1GA 4A14A 3ZFCA 1MMGA 4PJLA 4BBGA 3GBJA 2X7DA 4PJMA 2OWMA 5LT2A 5LT1A 1D0XA 4PFOA 2ZFLA 2MYSA 3KENA 1KK7A 1F9UA 1MMAA 3H4SA 4A1ZA 3T0QA 3KARA 1D0YA 2PG2A 2XT3A 2X2RA 1X88A 2FMEA 1VFVA 2XAEA 3ZFDA 2X7CA 2UYMA 5LT3A 4A5YA 3CJOA 2X7EA 1FMVA 4E7SA 2VB6A 1D0ZA 4GKRA 4BXNA 2HEHA 4A28A 3K5EA 3NWNA 3COBA 4ETPB 3K3BA 1G8XA 3ZCWA 2FL6A 1YRSA 2ZFJA 5GSZA 4E7ZA 2VVGA 1D1CA 2X51A 3LREA 3B6UA 4PJJA 1MMNA 2ZFMA 1LVKA 4AP0A 1V8JA 2V26A 1MMDA 2FKYA 3X2TA 4AS7A 5LT4A 5HLEA 2GRYA 2G1QA
chains in the Genus database with same CATH topology
1SDMA 3U06A 1GOJA 3PXNA 3L1CA 1FMWA 1VFXA 4A50A 2VASA 5LT0A 4FRZA 4DBRA 1I5SA 4ANJA 3WRDA 1VOMA 4PJNA 1Q0BA 1BR1A 4BN2A 3L9HA 4A51A 1CZ7A 2IEHA 1MNEA 1BR2A 1F9VA 2Q2ZA 3DC4A 3KINA 2ZFIA 4HNAK 4ZCAA 1F9WA 4LNUK 1RY6A 4ZHIA 4UBFA 1BR4A 2WOGA 1F9TA 2NCDA 4B7BA 3HQDA 1BG2A 1II6A 2Q2YA 4PFPA 4ETPA 2ZFKA 2FL2A 1N6MA 2UYIA 2Y65A 2GM1A 1D1AA 4Y05A 1LKXA 1T5CA 1VFWA 3CNZA 4DBQA 2Y5WA 3BFNA 2KINA 1D1BA 1VFZA 4PK4A 1I6IA 1V8KA 3B6VA 3WPNA 3DCBA 1MKJA 4H1GA 4A14A 3ZFCA 1MMGA 4PJLA 4BBGA 3GBJA 2X7DA 4PJMA 2OWMA 5LT2A 5LT1A 1D0XA 4PFOA 2ZFLA 2MYSA 3KENA 1KK7A 1F9UA 1MMAA 3H4SA 4A1ZA 3T0QA 3KARA 1D0YA 2PG2A 2XT3A 2X2RA 1X88A 2FMEA 1VFVA 2XAEA 3ZFDA 2X7CA 2UYMA 5LT3A 4A5YA 3CJOA 2X7EA 1FMVA 4E7SA 2VB6A 1D0ZA 4GKRA 4BXNA 2HEHA 4A28A 3K5EA 3NWNA 3COBA 3K3BA 1G8XA 3ZCWA 2FL6A 1YRSA 2ZFJA 5GSZA 4E7ZA 2VVGA 1D1CA 2X51A 3LREA 3B6UA 4PJJA 1MMNA 2ZFMA 1LVKA 4AP0A 1V8JA 2V26A 1MMDA 2FKYA 3X2TA 4AS7A 5LT4A 5HLEA 2GRYA 2G1QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SDM A;  3U06 A;  1GOJ A;  3PXN A;  3L1C A;  1FMW A;  1VFX A;  4A50 A;  2VAS A;  5LT0 A;  4FRZ A;  4DBR A;  1I5S A;  4ANJ A;  3WRD A;  1VOM A;  4PJN A;  1Q0B A;  1BR1 A;  4BN2 A;  3L9H A;  4A51 A;  1CZ7 A;  2IEH A;  1MNE A;  1BR2 A;  1F9V A;  2Q2Z A;  3DC4 A;  3KIN A;  2ZFI A;  4HNA K;  4ZCA A;  1F9W A;  4LNU K;  1RY6 A;  4ZHI A;  4UBF A;  1BR4 A;  2WOG A;  1F9T A;  2NCD A;  4B7B A;  3HQD A;  1BG2 A;  1II6 A;  2Q2Y A;  4PFP A;  4ETP A;  2ZFK A;  2FL2 A;  1N6M A;  2UYI A;  2Y65 A;  2GM1 A;  1D1A A;  4Y05 A;  1LKX A;  1T5C A;  1VFW A;  3CNZ A;  4DBQ A;  2Y5W A;  3BFN A;  2KIN A;  1D1B A;  1VFZ A;  4PK4 A;  1I6I A;  1V8K A;  3B6V A;  3WPN A;  3DCB A;  1MKJ A;  4H1G A;  4A14 A;  3ZFC A;  1MMG A;  4PJL A;  4BBG A;  3GBJ A;  2X7D A;  4PJM A;  2OWM A;  5LT2 A;  5LT1 A;  1D0X A;  4PFO A;  2ZFL A;  2MYS A;  3KEN A;  1KK7 A;  1F9U A;  1MMA A;  3H4S A;  4A1Z A;  3T0Q A;  3KAR A;  1D0Y A;  2PG2 A;  2XT3 A;  2X2R A;  1X88 A;  2FME A;  1VFV A;  2XAE A;  3ZFD A;  2X7C A;  2UYM A;  5LT3 A;  4A5Y A;  3CJO A;  2X7E A;  1FMV A;  4E7S A;  2VB6 A;  1D0Z A;  4GKR A;  4BXN A;  2HEH A;  4A28 A;  3K5E A;  3NWN A;  3COB A;  3K3B A;  1G8X A;  3ZCW A;  2FL6 A;  1YRS A;  2ZFJ A;  5GSZ A;  4E7Z A;  2VVG A;  1D1C A;  2X51 A;  3LRE A;  3B6U A;  4PJJ A;  1MMN A;  2ZFM A;  1LVK A;  4AP0 A;  1V8J A;  2V26 A;  1MMD A;  2FKY A;  3X2T A;  4AS7 A;  5LT4 A;  5HLE A;  2GRY A;  2G1Q A; 
#chains in the Genus database with same CATH topology
 1SDM A;  3U06 A;  1GOJ A;  3PXN A;  3L1C A;  1FMW A;  1VFX A;  4A50 A;  2VAS A;  5LT0 A;  4FRZ A;  4DBR A;  1I5S A;  4ANJ A;  3WRD A;  1VOM A;  4PJN A;  1Q0B A;  1BR1 A;  4BN2 A;  3L9H A;  4A51 A;  1CZ7 A;  2IEH A;  1MNE A;  1BR2 A;  1F9V A;  2Q2Z A;  3DC4 A;  3KIN A;  2ZFI A;  4HNA K;  4ZCA A;  1F9W A;  4LNU K;  1RY6 A;  4ZHI A;  4GKP A;  4UBF A;  1BR4 A;  2WOG A;  1F9T A;  2NCD A;  4B7B A;  3HQD A;  1BG2 A;  1II6 A;  2Q2Y A;  4PFP A;  4ETP A;  2ZFK A;  2FL2 A;  1N6M A;  2UYI A;  2Y65 A;  2GM1 A;  1D1A A;  4Y05 A;  1LKX A;  1T5C A;  1VFW A;  3CNZ A;  4DBQ A;  2Y5W A;  3BFN A;  2KIN A;  1D1B A;  1VFZ A;  4PK4 A;  1I6I A;  1V8K A;  3B6V A;  3WPN A;  3DCB A;  1MKJ A;  2O0A A;  4GKQ A;  4H1G A;  4A14 A;  3ZFC A;  1MMG A;  4PJL A;  4BBG A;  3GBJ A;  2X7D A;  4PJM A;  2OWM A;  5LT2 A;  5LT1 A;  1D0X A;  4PFO A;  2ZFL A;  2MYS A;  3KEN A;  1KK7 A;  1F9U A;  1MMA A;  3H4S A;  4A1Z A;  3T0Q A;  3KAR A;  1D0Y A;  2PG2 A;  2XT3 A;  2X2R A;  1X88 A;  2FME A;  1VFV A;  2XAE A;  3ZFD A;  2X7C A;  2UYM A;  5LT3 A;  4A5Y A;  3CJO A;  2X7E A;  1FMV A;  4E7S A;  2VB6 A;  1D0Z A;  4GKR A;  4BXN A;  2HEH A;  4A28 A;  3K5E A;  3NWN A;  3COB A;  4ETP B;  3K3B A;  1G8X A;  3ZCW A;  2FL6 A;  1YRS A;  2ZFJ A;  5GSZ A;  4E7Z A;  2VVG A;  1D1C A;  2X51 A;  3LRE A;  3B6U A;  4PJJ A;  1MMN A;  2ZFM A;  1LVK A;  4AP0 A;  1V8J A;  2V26 A;  1MMD A;  2FKY A;  3X2T A;  4AS7 A;  5LT4 A;  5HLE A;  2GRY A;  2G1Q A; 
#chains in the Genus database with same CATH homology
 1SDM A;  3U06 A;  1GOJ A;  3PXN A;  3L1C A;  1FMW A;  1VFX A;  4A50 A;  2VAS A;  5LT0 A;  4FRZ A;  4DBR A;  1I5S A;  4ANJ A;  3WRD A;  1VOM A;  4PJN A;  1Q0B A;  1BR1 A;  4BN2 A;  3L9H A;  4A51 A;  1CZ7 A;  2IEH A;  1MNE A;  1BR2 A;  1F9V A;  2Q2Z A;  3DC4 A;  3KIN A;  2ZFI A;  4HNA K;  4ZCA A;  1F9W A;  4LNU K;  1RY6 A;  4ZHI A;  4UBF A;  1BR4 A;  2WOG A;  1F9T A;  2NCD A;  4B7B A;  3HQD A;  1BG2 A;  1II6 A;  2Q2Y A;  4PFP A;  4ETP A;  2ZFK A;  2FL2 A;  1N6M A;  2UYI A;  2Y65 A;  2GM1 A;  1D1A A;  4Y05 A;  1LKX A;  1T5C A;  1VFW A;  3CNZ A;  4DBQ A;  2Y5W A;  3BFN A;  2KIN A;  1D1B A;  1VFZ A;  4PK4 A;  1I6I A;  1V8K A;  3B6V A;  3WPN A;  3DCB A;  1MKJ A;  4H1G A;  4A14 A;  3ZFC A;  1MMG A;  4PJL A;  4BBG A;  3GBJ A;  2X7D A;  4PJM A;  2OWM A;  5LT2 A;  5LT1 A;  1D0X A;  4PFO A;  2ZFL A;  2MYS A;  3KEN A;  1KK7 A;  1F9U A;  1MMA A;  3H4S A;  4A1Z A;  3T0Q A;  3KAR A;  1D0Y A;  2PG2 A;  2XT3 A;  2X2R A;  1X88 A;  2FME A;  1VFV A;  2XAE A;  3ZFD A;  2X7C A;  2UYM A;  5LT3 A;  4A5Y A;  3CJO A;  2X7E A;  1FMV A;  4E7S A;  2VB6 A;  1D0Z A;  4GKR A;  4BXN A;  2HEH A;  4A28 A;  3K5E A;  3NWN A;  3COB A;  3K3B A;  1G8X A;  3ZCW A;  2FL6 A;  1YRS A;  2ZFJ A;  5GSZ A;  4E7Z A;  2VVG A;  1D1C A;  2X51 A;  3LRE A;  3B6U A;  4PJJ A;  1MMN A;  2ZFM A;  1LVK A;  4AP0 A;  1V8J A;  2V26 A;  1MMD A;  2FKY A;  3X2T A;  4AS7 A;  5LT4 A;  5HLE A;  2GRY A;  2G1Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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