2GRYA

Crystal structure of the human kif2 motor domain in complex with adp
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
355
structure length
327
Chain Sequence
b'EIMCMIRDFRGSLDYRPLPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERDRQTRLEGAEINKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Kinesin-like protein KIF2
publication title Crystal structure of the human KIF2 motor domain in complex with ADP
rcsb
source organism Homo sapiens
molecule tags Transport protein
total genus 114
structure length 327
sequence length 355
ec nomenclature
pdb deposition date 2006-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 2gryA00
1LKXA 4GKRA 4PK4A 4ETPA 1GOJA 2X7EA 4ZHIA 2OWMA 1D0XA 1G8XA 5LT3A 1V8JA 1CZ7A 3WRDA 3H4SA 2FKYA 4A1ZA 4A14A 2X7DA 2KINA 4BBGA 1I5SA 1VFXA 4BXNA 3NWNA 4A50A 1MKJA 1F9VA 1MMDA 4AP0A 5HLEA 2VVGA 1D0ZA 3L1CA 4LNUK 4PFOA 2V26A 1VFWA 1T5CA 1MMGA 3HQDA 1V8KA 1X88A 3KENA 2X7CA 4BN2A 4PJJA 1F9TA 2Y65A 1D1BA 2WOGA 1F9WA 2FMEA 1D0YA 2VASA 3PXNA 4H1GA 3GBJA 4FRZA 1YRSA 1VFZA 5LT2A 3CNZA 4PJMA 1MMAA 3DC4A 1VFVA 1VOMA 3LREA 4A5YA 2ZFMA 3KINA 4ANJA 4Y05A 1SDMA 1LVKA 3K5EA 4PFPA 3WPNA 4DBQA 3CJOA 2PG2A 1N6MA 1BR1A 4A51A 5GSZA 1BG2A 2ZFLA 2ZFIA 1BR2A 5LT1A 1F9UA 2MYSA 3KARA 1II6A 4PJLA 3DCBA 2Y5WA 1D1CA 3ZFCA 4E7ZA 4DBRA 2FL6A 1Q0BA 3U06A 1BR4A 1D1AA 3B6UA 5LT0A 1MMNA 2Q2YA 3ZCWA 2UYMA 2ZFKA 2GRYA 2UYIA 1FMWA 2X51A 1MNEA 1RY6A 2NCDA 4AS7A 3X2TA 1FMVA 1KK7A 2FL2A 3B6VA 2GM1A 3COBA 2G1QA 1I6IA 2Q2ZA 2XT3A 2HEHA 2IEHA 4UBFA 2X2RA 2ZFJA 3L9HA 4B7BA 3T0QA 3BFNA 4E7SA 4PJNA 3ZFDA 3K3BA 4ZCAA 2VB6A 4A28A 4HNAK 2XAEA 5LT4A
chains in the Genus database with same CATH superfamily
1LKXA 4GKRA 4PK4A 4ETPA 1GOJA 4ETPB 2X7EA 4GKPA 4ZHIA 2OWMA 1D0XA 1G8XA 5LT3A 1V8JA 1CZ7A 3WRDA 3H4SA 2FKYA 4A1ZA 4A14A 2X7DA 2KINA 4BBGA 1I5SA 2O0AA 1VFXA 4BXNA 3NWNA 4A50A 1MKJA 1F9VA 1MMDA 4AP0A 5HLEA 2VVGA 1D0ZA 3L1CA 4LNUK 4PFOA 2V26A 1VFWA 1T5CA 1MMGA 3HQDA 1V8KA 1X88A 3KENA 2X7CA 4BN2A 4PJJA 1F9TA 2Y65A 1D1BA 2WOGA 1F9WA 2FMEA 1D0YA 2VASA 3PXNA 4H1GA 3GBJA 4FRZA 1YRSA 1VFZA 5LT2A 3CNZA 4PJMA 1MMAA 3DC4A 1VFVA 1VOMA 3LREA 4A5YA 2ZFMA 3KINA 4ANJA 4Y05A 1SDMA 1LVKA 3K5EA 4PFPA 3WPNA 4DBQA 3CJOA 2PG2A 1N6MA 1BR1A 4A51A 5GSZA 1BG2A 2ZFLA 2ZFIA 1BR2A 5LT1A 1F9UA 2MYSA 3KARA 1II6A 4PJLA 3DCBA 2Y5WA 1D1CA 3ZFCA 4E7ZA 4DBRA 2FL6A 1Q0BA 3U06A 1BR4A 1D1AA 3B6UA 5LT0A 1MMNA 2Q2YA 3ZCWA 2UYMA 2ZFKA 2GRYA 2UYIA 1FMWA 2X51A 1MNEA 1RY6A 2NCDA 4AS7A 3X2TA 1FMVA 1KK7A 2FL2A 3B6VA 2GM1A 3COBA 2G1QA 1I6IA 4GKQA 2Q2ZA 2XT3A 2HEHA 2IEHA 4UBFA 2X2RA 2ZFJA 3L9HA 4B7BA 3T0QA 3BFNA 4E7SA 4PJNA 3ZFDA 3K3BA 4ZCAA 2VB6A 4A28A 4HNAK 2XAEA 5LT4A
chains in the Genus database with same CATH topology
1LKXA 4GKRA 4PK4A 4ETPA 1GOJA 2X7EA 4ZHIA 2OWMA 1D0XA 1G8XA 5LT3A 1V8JA 1CZ7A 3WRDA 3H4SA 2FKYA 4A1ZA 4A14A 2X7DA 2KINA 4BBGA 1I5SA 1VFXA 4BXNA 3NWNA 4A50A 1MKJA 1F9VA 1MMDA 4AP0A 5HLEA 2VVGA 1D0ZA 3L1CA 4LNUK 4PFOA 2V26A 1VFWA 1T5CA 1MMGA 3HQDA 1V8KA 1X88A 3KENA 2X7CA 4BN2A 4PJJA 1F9TA 2Y65A 1D1BA 2WOGA 1F9WA 2FMEA 1D0YA 2VASA 3PXNA 4H1GA 3GBJA 4FRZA 1YRSA 1VFZA 5LT2A 3CNZA 4PJMA 1MMAA 3DC4A 1VFVA 1VOMA 3LREA 4A5YA 2ZFMA 3KINA 4ANJA 4Y05A 1SDMA 1LVKA 3K5EA 4PFPA 3WPNA 4DBQA 3CJOA 2PG2A 1N6MA 1BR1A 4A51A 5GSZA 1BG2A 2ZFLA 2ZFIA 1BR2A 5LT1A 1F9UA 2MYSA 3KARA 1II6A 4PJLA 3DCBA 2Y5WA 1D1CA 3ZFCA 4E7ZA 4DBRA 2FL6A 1Q0BA 3U06A 1BR4A 1D1AA 3B6UA 5LT0A 1MMNA 2Q2YA 3ZCWA 2UYMA 2ZFKA 2GRYA 2UYIA 1FMWA 2X51A 1MNEA 1RY6A 2NCDA 4AS7A 3X2TA 1FMVA 1KK7A 2FL2A 3B6VA 2GM1A 3COBA 2G1QA 1I6IA 2Q2ZA 2XT3A 2HEHA 2IEHA 4UBFA 2X2RA 2ZFJA 3L9HA 4B7BA 3T0QA 3BFNA 4E7SA 4PJNA 3ZFDA 3K3BA 4ZCAA 2VB6A 4A28A 4HNAK 2XAEA 5LT4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LKX A;  4GKR A;  4PK4 A;  4ETP A;  1GOJ A;  2X7E A;  4ZHI A;  2OWM A;  1D0X A;  1G8X A;  5LT3 A;  1V8J A;  1CZ7 A;  3WRD A;  3H4S A;  2FKY A;  4A1Z A;  4A14 A;  2X7D A;  2KIN A;  4BBG A;  1I5S A;  1VFX A;  4BXN A;  3NWN A;  4A50 A;  1MKJ A;  1F9V A;  1MMD A;  4AP0 A;  5HLE A;  2VVG A;  1D0Z A;  3L1C A;  4LNU K;  4PFO A;  2V26 A;  1VFW A;  1T5C A;  1MMG A;  3HQD A;  1V8K A;  1X88 A;  3KEN A;  2X7C A;  4BN2 A;  4PJJ A;  1F9T A;  2Y65 A;  1D1B A;  2WOG A;  1F9W A;  2FME A;  1D0Y A;  2VAS A;  3PXN A;  4H1G A;  3GBJ A;  4FRZ A;  1YRS A;  1VFZ A;  5LT2 A;  3CNZ A;  4PJM A;  1MMA A;  3DC4 A;  1VFV A;  1VOM A;  3LRE A;  4A5Y A;  2ZFM A;  3KIN A;  4ANJ A;  4Y05 A;  1SDM A;  1LVK A;  3K5E A;  4PFP A;  3WPN A;  4DBQ A;  3CJO A;  2PG2 A;  1N6M A;  1BR1 A;  4A51 A;  5GSZ A;  1BG2 A;  2ZFL A;  2ZFI A;  1BR2 A;  5LT1 A;  1F9U A;  2MYS A;  3KAR A;  1II6 A;  4PJL A;  3DCB A;  2Y5W A;  1D1C A;  3ZFC A;  4E7Z A;  4DBR A;  2FL6 A;  1Q0B A;  3U06 A;  1BR4 A;  1D1A A;  3B6U A;  5LT0 A;  1MMN A;  2Q2Y A;  3ZCW A;  2UYM A;  2ZFK A;  2GRY A;  2UYI A;  1FMW A;  2X51 A;  1MNE A;  1RY6 A;  2NCD A;  4AS7 A;  3X2T A;  1FMV A;  1KK7 A;  2FL2 A;  3B6V A;  2GM1 A;  3COB A;  2G1Q A;  1I6I A;  2Q2Z A;  2XT3 A;  2HEH A;  2IEH A;  4UBF A;  2X2R A;  2ZFJ A;  3L9H A;  4B7B A;  3T0Q A;  3BFN A;  4E7S A;  4PJN A;  3ZFD A;  3K3B A;  4ZCA A;  2VB6 A;  4A28 A;  4HNA K;  2XAE A;  5LT4 A; 
#chains in the Genus database with same CATH topology
 1LKX A;  4GKR A;  4PK4 A;  4ETP A;  1GOJ A;  4ETP B;  2X7E A;  4GKP A;  4ZHI A;  2OWM A;  1D0X A;  1G8X A;  5LT3 A;  1V8J A;  1CZ7 A;  3WRD A;  3H4S A;  2FKY A;  4A1Z A;  4A14 A;  2X7D A;  2KIN A;  4BBG A;  1I5S A;  2O0A A;  1VFX A;  4BXN A;  3NWN A;  4A50 A;  1MKJ A;  1F9V A;  1MMD A;  4AP0 A;  5HLE A;  2VVG A;  1D0Z A;  3L1C A;  4LNU K;  4PFO A;  2V26 A;  1VFW A;  1T5C A;  1MMG A;  3HQD A;  1V8K A;  1X88 A;  3KEN A;  2X7C A;  4BN2 A;  4PJJ A;  1F9T A;  2Y65 A;  1D1B A;  2WOG A;  1F9W A;  2FME A;  1D0Y A;  2VAS A;  3PXN A;  4H1G A;  3GBJ A;  4FRZ A;  1YRS A;  1VFZ A;  5LT2 A;  3CNZ A;  4PJM A;  1MMA A;  3DC4 A;  1VFV A;  1VOM A;  3LRE A;  4A5Y A;  2ZFM A;  3KIN A;  4ANJ A;  4Y05 A;  1SDM A;  1LVK A;  3K5E A;  4PFP A;  3WPN A;  4DBQ A;  3CJO A;  2PG2 A;  1N6M A;  1BR1 A;  4A51 A;  5GSZ A;  1BG2 A;  2ZFL A;  2ZFI A;  1BR2 A;  5LT1 A;  1F9U A;  2MYS A;  3KAR A;  1II6 A;  4PJL A;  3DCB A;  2Y5W A;  1D1C A;  3ZFC A;  4E7Z A;  4DBR A;  2FL6 A;  1Q0B A;  3U06 A;  1BR4 A;  1D1A A;  3B6U A;  5LT0 A;  1MMN A;  2Q2Y A;  3ZCW A;  2UYM A;  2ZFK A;  2GRY A;  2UYI A;  1FMW A;  2X51 A;  1MNE A;  1RY6 A;  2NCD A;  4AS7 A;  3X2T A;  1FMV A;  1KK7 A;  2FL2 A;  3B6V A;  2GM1 A;  3COB A;  2G1Q A;  1I6I A;  4GKQ A;  2Q2Z A;  2XT3 A;  2HEH A;  2IEH A;  4UBF A;  2X2R A;  2ZFJ A;  3L9H A;  4B7B A;  3T0Q A;  3BFN A;  4E7S A;  4PJN A;  3ZFD A;  3K3B A;  4ZCA A;  2VB6 A;  4A28 A;  4HNA K;  2XAE A;  5LT4 A; 
#chains in the Genus database with same CATH homology
 1LKX A;  4GKR A;  4PK4 A;  4ETP A;  1GOJ A;  2X7E A;  4ZHI A;  2OWM A;  1D0X A;  1G8X A;  5LT3 A;  1V8J A;  1CZ7 A;  3WRD A;  3H4S A;  2FKY A;  4A1Z A;  4A14 A;  2X7D A;  2KIN A;  4BBG A;  1I5S A;  1VFX A;  4BXN A;  3NWN A;  4A50 A;  1MKJ A;  1F9V A;  1MMD A;  4AP0 A;  5HLE A;  2VVG A;  1D0Z A;  3L1C A;  4LNU K;  4PFO A;  2V26 A;  1VFW A;  1T5C A;  1MMG A;  3HQD A;  1V8K A;  1X88 A;  3KEN A;  2X7C A;  4BN2 A;  4PJJ A;  1F9T A;  2Y65 A;  1D1B A;  2WOG A;  1F9W A;  2FME A;  1D0Y A;  2VAS A;  3PXN A;  4H1G A;  3GBJ A;  4FRZ A;  1YRS A;  1VFZ A;  5LT2 A;  3CNZ A;  4PJM A;  1MMA A;  3DC4 A;  1VFV A;  1VOM A;  3LRE A;  4A5Y A;  2ZFM A;  3KIN A;  4ANJ A;  4Y05 A;  1SDM A;  1LVK A;  3K5E A;  4PFP A;  3WPN A;  4DBQ A;  3CJO A;  2PG2 A;  1N6M A;  1BR1 A;  4A51 A;  5GSZ A;  1BG2 A;  2ZFL A;  2ZFI A;  1BR2 A;  5LT1 A;  1F9U A;  2MYS A;  3KAR A;  1II6 A;  4PJL A;  3DCB A;  2Y5W A;  1D1C A;  3ZFC A;  4E7Z A;  4DBR A;  2FL6 A;  1Q0B A;  3U06 A;  1BR4 A;  1D1A A;  3B6U A;  5LT0 A;  1MMN A;  2Q2Y A;  3ZCW A;  2UYM A;  2ZFK A;  2GRY A;  2UYI A;  1FMW A;  2X51 A;  1MNE A;  1RY6 A;  2NCD A;  4AS7 A;  3X2T A;  1FMV A;  1KK7 A;  2FL2 A;  3B6V A;  2GM1 A;  3COB A;  2G1Q A;  1I6I A;  2Q2Z A;  2XT3 A;  2HEH A;  2IEH A;  4UBF A;  2X2R A;  2ZFJ A;  3L9H A;  4B7B A;  3T0Q A;  3BFN A;  4E7S A;  4PJN A;  3ZFD A;  3K3B A;  4ZCA A;  2VB6 A;  4A28 A;  4HNA K;  2XAE A;  5LT4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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