2GRYA

Crystal structure of the human kif2 motor domain in complex with adp
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
355
structure length
327
Chain Sequence
EIMCMIRDFRGSLDYRPLPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERDRQTRLEGAEINKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Kinesin-like protein KIF2
publication title Crystal structure of the human KIF2 motor domain in complex with ADP
rcsb
source organism Homo sapiens
molecule tags Transport protein
total genus 114
structure length 327
sequence length 355
ec nomenclature
pdb deposition date 2006-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 2gryA00
1RY6A 2ZFMA 5LT2A 3DCBA 3GBJA 1CZ7A 1Q0BA 2X7DA 1MMNA 3KARA 3U06A 4PJMA 4H1GA 3CNZA 4BN2A 1VFZA 3DC4A 2GRYA 2G1QA 4AS7A 3PXNA 4BBGA 1V8KA 1D0XA 2FKYA 2V26A 2UYMA 1BR1A 1MMGA 3HQDA 3ZFDA 4A28A 3WRDA 1G8XA 4PK4A 1MMDA 3B6UA 1II6A 1F9TA 1D1CA 1F9UA 3T0QA 1LKXA 1FMVA 2X51A 1MMAA 3K5EA 4PJNA 3KENA 3BFNA 2VB6A 5LT1A 1D0ZA 1MKJA 2PG2A 4FRZA 4A14A 1BR4A 4ETPA 1MNEA 3WPNA 2Q2ZA 3X2TA 2XAEA 4DBQA 2UYIA 2FMEA 4A51A 1BR2A 4E7ZA 1YRSA 4A50A 1F9WA 1KK7A 2XT3A 5HLEA 2MYSA 2VVGA 4ANJA 3K3BA 2X7CA 1D0YA 4BXNA 1F9VA 4GKRA 3L9HA 4Y05A 4A1ZA 2ZFJA 4LNUK 4PFOA 1BG2A 3B6VA 4HNAK 4ZCAA 4A5YA 1I5SA 3ZFCA 1V8JA 5LT3A 4UBFA 4PJLA 1SDMA 2NCDA 2IEHA 2HEHA 2ZFLA 2KINA 5GSZA 2ZFKA 4PFPA 2GM1A 2WOGA 1VFXA 1VFVA 4B7BA 1D1AA 2OWMA 2FL6A 1VFWA 2Q2YA 1VOMA 2Y5WA 4PJJA 2ZFIA 5LT4A 1FMWA 2VASA 2X7EA 3CJOA 4AP0A 4DBRA 3LREA 3L1CA 3COBA 1X88A 1N6MA 3ZCWA 5LT0A 1D1BA 2Y65A 4ZHIA 1I6IA 2X2RA 3H4SA 4E7SA 2FL2A 3KINA 3NWNA 1T5CA 1LVKA 1GOJA
chains in the Genus database with same CATH superfamily
1RY6A 2ZFMA 5LT2A 3DCBA 3GBJA 1CZ7A 1Q0BA 2X7DA 1MMNA 3KARA 3U06A 4PJMA 4H1GA 3CNZA 4BN2A 1VFZA 3DC4A 2GRYA 2G1QA 4AS7A 3PXNA 4BBGA 1V8KA 1D0XA 2FKYA 2V26A 2UYMA 1BR1A 1MMGA 3HQDA 3ZFDA 4A28A 3WRDA 4ETPB 1G8XA 4PK4A 1MMDA 3B6UA 1II6A 4GKQA 1F9TA 1D1CA 1F9UA 3T0QA 1LKXA 1FMVA 2X51A 1MMAA 3K5EA 4PJNA 3KENA 3BFNA 2VB6A 5LT1A 1D0ZA 1MKJA 2PG2A 4FRZA 4A14A 1BR4A 4ETPA 1MNEA 3WPNA 2Q2ZA 3X2TA 2XAEA 4DBQA 2UYIA 2FMEA 4A51A 1BR2A 4E7ZA 1YRSA 4A50A 1F9WA 1KK7A 2XT3A 5HLEA 2MYSA 2VVGA 4ANJA 3K3BA 2X7CA 1D0YA 4BXNA 1F9VA 4GKRA 2O0AA 3L9HA 4Y05A 4A1ZA 2ZFJA 4LNUK 4PFOA 1BG2A 3B6VA 4HNAK 4ZCAA 4A5YA 1I5SA 3ZFCA 1V8JA 5LT3A 4UBFA 4PJLA 1SDMA 2NCDA 2IEHA 2HEHA 2ZFLA 2KINA 5GSZA 2ZFKA 4GKPA 4PFPA 2GM1A 2WOGA 1VFXA 1VFVA 4B7BA 1D1AA 2OWMA 2FL6A 1VFWA 2Q2YA 1VOMA 2Y5WA 4PJJA 2ZFIA 5LT4A 1FMWA 2VASA 2X7EA 3CJOA 4AP0A 4DBRA 3LREA 3L1CA 3COBA 1X88A 1N6MA 3ZCWA 5LT0A 1D1BA 2Y65A 4ZHIA 1I6IA 2X2RA 3H4SA 4E7SA 2FL2A 3KINA 3NWNA 1T5CA 1LVKA 1GOJA
chains in the Genus database with same CATH topology
1RY6A 2ZFMA 5LT2A 3DCBA 3GBJA 1CZ7A 1Q0BA 2X7DA 1MMNA 3KARA 3U06A 4PJMA 4H1GA 3CNZA 4BN2A 1VFZA 3DC4A 2GRYA 2G1QA 4AS7A 3PXNA 4BBGA 1V8KA 1D0XA 2FKYA 2V26A 2UYMA 1BR1A 1MMGA 3HQDA 3ZFDA 4A28A 3WRDA 1G8XA 4PK4A 1MMDA 3B6UA 1II6A 1F9TA 1D1CA 1F9UA 3T0QA 1LKXA 1FMVA 2X51A 1MMAA 3K5EA 4PJNA 3KENA 3BFNA 2VB6A 5LT1A 1D0ZA 1MKJA 2PG2A 4FRZA 4A14A 1BR4A 4ETPA 1MNEA 3WPNA 2Q2ZA 3X2TA 2XAEA 4DBQA 2UYIA 2FMEA 4A51A 1BR2A 4E7ZA 1YRSA 4A50A 1F9WA 1KK7A 2XT3A 5HLEA 2MYSA 2VVGA 4ANJA 3K3BA 2X7CA 1D0YA 4BXNA 1F9VA 4GKRA 3L9HA 4Y05A 4A1ZA 2ZFJA 4LNUK 4PFOA 1BG2A 3B6VA 4HNAK 4ZCAA 4A5YA 1I5SA 3ZFCA 1V8JA 5LT3A 4UBFA 4PJLA 1SDMA 2NCDA 2IEHA 2HEHA 2ZFLA 2KINA 5GSZA 2ZFKA 4PFPA 2GM1A 2WOGA 1VFXA 1VFVA 4B7BA 1D1AA 2OWMA 2FL6A 1VFWA 2Q2YA 1VOMA 2Y5WA 4PJJA 2ZFIA 5LT4A 1FMWA 2VASA 2X7EA 3CJOA 4AP0A 4DBRA 3LREA 3L1CA 3COBA 1X88A 1N6MA 3ZCWA 5LT0A 1D1BA 2Y65A 4ZHIA 1I6IA 2X2RA 3H4SA 4E7SA 2FL2A 3KINA 3NWNA 1T5CA 1LVKA 1GOJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RY6 A;  2ZFM A;  5LT2 A;  3DCB A;  3GBJ A;  1CZ7 A;  1Q0B A;  2X7D A;  1MMN A;  3KAR A;  3U06 A;  4PJM A;  4H1G A;  3CNZ A;  4BN2 A;  1VFZ A;  3DC4 A;  2GRY A;  2G1Q A;  4AS7 A;  3PXN A;  4BBG A;  1V8K A;  1D0X A;  2FKY A;  2V26 A;  2UYM A;  1BR1 A;  1MMG A;  3HQD A;  3ZFD A;  4A28 A;  3WRD A;  1G8X A;  4PK4 A;  1MMD A;  3B6U A;  1II6 A;  1F9T A;  1D1C A;  1F9U A;  3T0Q A;  1LKX A;  1FMV A;  2X51 A;  1MMA A;  3K5E A;  4PJN A;  3KEN A;  3BFN A;  2VB6 A;  5LT1 A;  1D0Z A;  1MKJ A;  2PG2 A;  4FRZ A;  4A14 A;  1BR4 A;  4ETP A;  1MNE A;  3WPN A;  2Q2Z A;  3X2T A;  2XAE A;  4DBQ A;  2UYI A;  2FME A;  4A51 A;  1BR2 A;  4E7Z A;  1YRS A;  4A50 A;  1F9W A;  1KK7 A;  2XT3 A;  5HLE A;  2MYS A;  2VVG A;  4ANJ A;  3K3B A;  2X7C A;  1D0Y A;  4BXN A;  1F9V A;  4GKR A;  3L9H A;  4Y05 A;  4A1Z A;  2ZFJ A;  4LNU K;  4PFO A;  1BG2 A;  3B6V A;  4HNA K;  4ZCA A;  4A5Y A;  1I5S A;  3ZFC A;  1V8J A;  5LT3 A;  4UBF A;  4PJL A;  1SDM A;  2NCD A;  2IEH A;  2HEH A;  2ZFL A;  2KIN A;  5GSZ A;  2ZFK A;  4PFP A;  2GM1 A;  2WOG A;  1VFX A;  1VFV A;  4B7B A;  1D1A A;  2OWM A;  2FL6 A;  1VFW A;  2Q2Y A;  1VOM A;  2Y5W A;  4PJJ A;  2ZFI A;  5LT4 A;  1FMW A;  2VAS A;  2X7E A;  3CJO A;  4AP0 A;  4DBR A;  3LRE A;  3L1C A;  3COB A;  1X88 A;  1N6M A;  3ZCW A;  5LT0 A;  1D1B A;  2Y65 A;  4ZHI A;  1I6I A;  2X2R A;  3H4S A;  4E7S A;  2FL2 A;  3KIN A;  3NWN A;  1T5C A;  1LVK A;  1GOJ A; 
#chains in the Genus database with same CATH topology
 1RY6 A;  2ZFM A;  5LT2 A;  3DCB A;  3GBJ A;  1CZ7 A;  1Q0B A;  2X7D A;  1MMN A;  3KAR A;  3U06 A;  4PJM A;  4H1G A;  3CNZ A;  4BN2 A;  1VFZ A;  3DC4 A;  2GRY A;  2G1Q A;  4AS7 A;  3PXN A;  4BBG A;  1V8K A;  1D0X A;  2FKY A;  2V26 A;  2UYM A;  1BR1 A;  1MMG A;  3HQD A;  3ZFD A;  4A28 A;  3WRD A;  4ETP B;  1G8X A;  4PK4 A;  1MMD A;  3B6U A;  1II6 A;  4GKQ A;  1F9T A;  1D1C A;  1F9U A;  3T0Q A;  1LKX A;  1FMV A;  2X51 A;  1MMA A;  3K5E A;  4PJN A;  3KEN A;  3BFN A;  2VB6 A;  5LT1 A;  1D0Z A;  1MKJ A;  2PG2 A;  4FRZ A;  4A14 A;  1BR4 A;  4ETP A;  1MNE A;  3WPN A;  2Q2Z A;  3X2T A;  2XAE A;  4DBQ A;  2UYI A;  2FME A;  4A51 A;  1BR2 A;  4E7Z A;  1YRS A;  4A50 A;  1F9W A;  1KK7 A;  2XT3 A;  5HLE A;  2MYS A;  2VVG A;  4ANJ A;  3K3B A;  2X7C A;  1D0Y A;  4BXN A;  1F9V A;  4GKR A;  2O0A A;  3L9H A;  4Y05 A;  4A1Z A;  2ZFJ A;  4LNU K;  4PFO A;  1BG2 A;  3B6V A;  4HNA K;  4ZCA A;  4A5Y A;  1I5S A;  3ZFC A;  1V8J A;  5LT3 A;  4UBF A;  4PJL A;  1SDM A;  2NCD A;  2IEH A;  2HEH A;  2ZFL A;  2KIN A;  5GSZ A;  2ZFK A;  4GKP A;  4PFP A;  2GM1 A;  2WOG A;  1VFX A;  1VFV A;  4B7B A;  1D1A A;  2OWM A;  2FL6 A;  1VFW A;  2Q2Y A;  1VOM A;  2Y5W A;  4PJJ A;  2ZFI A;  5LT4 A;  1FMW A;  2VAS A;  2X7E A;  3CJO A;  4AP0 A;  4DBR A;  3LRE A;  3L1C A;  3COB A;  1X88 A;  1N6M A;  3ZCW A;  5LT0 A;  1D1B A;  2Y65 A;  4ZHI A;  1I6I A;  2X2R A;  3H4S A;  4E7S A;  2FL2 A;  3KIN A;  3NWN A;  1T5C A;  1LVK A;  1GOJ A; 
#chains in the Genus database with same CATH homology
 1RY6 A;  2ZFM A;  5LT2 A;  3DCB A;  3GBJ A;  1CZ7 A;  1Q0B A;  2X7D A;  1MMN A;  3KAR A;  3U06 A;  4PJM A;  4H1G A;  3CNZ A;  4BN2 A;  1VFZ A;  3DC4 A;  2GRY A;  2G1Q A;  4AS7 A;  3PXN A;  4BBG A;  1V8K A;  1D0X A;  2FKY A;  2V26 A;  2UYM A;  1BR1 A;  1MMG A;  3HQD A;  3ZFD A;  4A28 A;  3WRD A;  1G8X A;  4PK4 A;  1MMD A;  3B6U A;  1II6 A;  1F9T A;  1D1C A;  1F9U A;  3T0Q A;  1LKX A;  1FMV A;  2X51 A;  1MMA A;  3K5E A;  4PJN A;  3KEN A;  3BFN A;  2VB6 A;  5LT1 A;  1D0Z A;  1MKJ A;  2PG2 A;  4FRZ A;  4A14 A;  1BR4 A;  4ETP A;  1MNE A;  3WPN A;  2Q2Z A;  3X2T A;  2XAE A;  4DBQ A;  2UYI A;  2FME A;  4A51 A;  1BR2 A;  4E7Z A;  1YRS A;  4A50 A;  1F9W A;  1KK7 A;  2XT3 A;  5HLE A;  2MYS A;  2VVG A;  4ANJ A;  3K3B A;  2X7C A;  1D0Y A;  4BXN A;  1F9V A;  4GKR A;  3L9H A;  4Y05 A;  4A1Z A;  2ZFJ A;  4LNU K;  4PFO A;  1BG2 A;  3B6V A;  4HNA K;  4ZCA A;  4A5Y A;  1I5S A;  3ZFC A;  1V8J A;  5LT3 A;  4UBF A;  4PJL A;  1SDM A;  2NCD A;  2IEH A;  2HEH A;  2ZFL A;  2KIN A;  5GSZ A;  2ZFK A;  4PFP A;  2GM1 A;  2WOG A;  1VFX A;  1VFV A;  4B7B A;  1D1A A;  2OWM A;  2FL6 A;  1VFW A;  2Q2Y A;  1VOM A;  2Y5W A;  4PJJ A;  2ZFI A;  5LT4 A;  1FMW A;  2VAS A;  2X7E A;  3CJO A;  4AP0 A;  4DBR A;  3LRE A;  3L1C A;  3COB A;  1X88 A;  1N6M A;  3ZCW A;  5LT0 A;  1D1B A;  2Y65 A;  4ZHI A;  1I6I A;  2X2R A;  3H4S A;  4E7S A;  2FL2 A;  3KIN A;  3NWN A;  1T5C A;  1LVK A;  1GOJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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