3HQDA

Human kinesin eg5 motor domain in complex with amppnp and mg2+
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
350
structure length
350
Chain Sequence
KNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title ATP Hydrolysis in Eg5 Kinesin Involves a Catalytic Two-water Mechanism.
pubmed doi rcsb
molecule tags Motor protein
source organism Homo sapiens
molecule keywords Kinesin-like protein KIF11
total genus 112
structure length 350
sequence length 350
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-06-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 3hqdA00
2GRYA 1T5CA 4H1GA 1BR4A 4PK4A 5GSZA 1BR1A 1BR2A 2ZFIA 1Q0BA 1CZ7A 4HNAK 2FL6A 1MMNA 2VVGA 1D1CA 3H4SA 1GOJA 3L1CA 2ZFLA 2UYIA 4PJJA 4ZHIA 4ZCAA 4A14A 1F9WA 4DBQA 3BFNA 4GKRA 4E7ZA 2IEHA 3K5EA 3KARA 4AS7A 2ZFKA 3HQDA 5LT3A 1F9VA 2V26A 5LT0A 1MMDA 4PJNA 4UBFA 4A51A 1BG2A 1LKXA 5HLEA 3COBA 2XT3A 3L9HA 2MYSA 2Q2YA 1V8JA 4PFPA 2XAEA 4E7SA 3U06A 1N6MA 2ZFMA 1X88A 3CNZA 2FKYA 1D1AA 2Y65A 1KK7A 1D0YA 3T0QA 1VFVA 4PJMA 4A50A 5LT2A 2KINA 4A1ZA 4LNUK 1G8XA 3ZFCA 4ANJA 1I6IA 4PFOA 1V8KA 5LT1A 1D0ZA 2X7EA 2GM1A 4DBRA 1MNEA 1SDMA 2X7DA 5LT4A 2PG2A 1RY6A 2HEHA 2Q2ZA 4AP0A 4A5YA 1F9UA 3B6UA 1II6A 4B7BA 1I5SA 3LREA 2UYMA 3K3BA 3KINA 1D1BA 2ZFJA 4ETPA 1MMAA 3X2TA 4BN2A 2VB6A 2FMEA 2X2RA 2G1QA 1VOMA 4BBGA 3DCBA 3WPNA 2NCDA 3WRDA 1FMWA 2FL2A 2X51A 1MKJA 2Y5WA 4Y05A 3B6VA 3CJOA 3ZFDA 1VFWA 3ZCWA 2WOGA 1YRSA 4PJLA 1FMVA 3DC4A 2OWMA 4FRZA 1D0XA 1LVKA 2X7CA 2VASA 4BXNA 4A28A 3GBJA 3NWNA 3PXNA 3KENA 1VFZA 1MMGA 1VFXA 1F9TA
chains in the Genus database with same CATH superfamily
2GRYA 1T5CA 4H1GA 1BR4A 4PK4A 5GSZA 1BR1A 1BR2A 2ZFIA 1Q0BA 1CZ7A 4HNAK 2FL6A 1MMNA 2VVGA 1D1CA 3H4SA 2O0AA 1GOJA 3L1CA 2ZFLA 2UYIA 4PJJA 4ZHIA 4ZCAA 4A14A 1F9WA 4DBQA 3BFNA 4GKRA 4E7ZA 2IEHA 3K5EA 3KARA 4AS7A 2ZFKA 3HQDA 5LT3A 1F9VA 4GKPA 2V26A 5LT0A 1MMDA 4PJNA 4UBFA 4A51A 1BG2A 1LKXA 5HLEA 3COBA 2XT3A 3L9HA 2MYSA 2Q2YA 1V8JA 4PFPA 2XAEA 4E7SA 3U06A 1N6MA 2ZFMA 1X88A 3CNZA 2FKYA 1D1AA 2Y65A 1KK7A 1D0YA 3T0QA 1VFVA 4PJMA 4A50A 5LT2A 2KINA 4A1ZA 4LNUK 1G8XA 3ZFCA 4ANJA 1I6IA 4PFOA 1V8KA 5LT1A 1D0ZA 2X7EA 2GM1A 4DBRA 1MNEA 1SDMA 2X7DA 5LT4A 2PG2A 1RY6A 2HEHA 2Q2ZA 4AP0A 4A5YA 1F9UA 3B6UA 1II6A 4B7BA 1I5SA 3LREA 2UYMA 3K3BA 3KINA 1D1BA 2ZFJA 4ETPA 1MMAA 3X2TA 4BN2A 2VB6A 2FMEA 2X2RA 2G1QA 1VOMA 4BBGA 4ETPB 3DCBA 3WPNA 2NCDA 3WRDA 1FMWA 2FL2A 2X51A 4GKQA 1MKJA 2Y5WA 4Y05A 3B6VA 3CJOA 3ZFDA 1VFWA 3ZCWA 2WOGA 1YRSA 4PJLA 1FMVA 3DC4A 2OWMA 4FRZA 1D0XA 1LVKA 2X7CA 2VASA 4BXNA 4A28A 3GBJA 3NWNA 3PXNA 3KENA 1VFZA 1MMGA 1VFXA 1F9TA
chains in the Genus database with same CATH topology
2GRYA 1T5CA 4H1GA 1BR4A 4PK4A 5GSZA 1BR1A 1BR2A 2ZFIA 1Q0BA 1CZ7A 4HNAK 2FL6A 1MMNA 2VVGA 1D1CA 3H4SA 1GOJA 3L1CA 2ZFLA 2UYIA 4PJJA 4ZHIA 4ZCAA 4A14A 1F9WA 4DBQA 3BFNA 4GKRA 4E7ZA 2IEHA 3K5EA 3KARA 4AS7A 2ZFKA 3HQDA 5LT3A 1F9VA 2V26A 5LT0A 1MMDA 4PJNA 4UBFA 4A51A 1BG2A 1LKXA 5HLEA 3COBA 2XT3A 3L9HA 2MYSA 2Q2YA 1V8JA 4PFPA 2XAEA 4E7SA 3U06A 1N6MA 2ZFMA 1X88A 3CNZA 2FKYA 1D1AA 2Y65A 1KK7A 1D0YA 3T0QA 1VFVA 4PJMA 4A50A 5LT2A 2KINA 4A1ZA 4LNUK 1G8XA 3ZFCA 4ANJA 1I6IA 4PFOA 1V8KA 5LT1A 1D0ZA 2X7EA 2GM1A 4DBRA 1MNEA 1SDMA 2X7DA 5LT4A 2PG2A 1RY6A 2HEHA 2Q2ZA 4AP0A 4A5YA 1F9UA 3B6UA 1II6A 4B7BA 1I5SA 3LREA 2UYMA 3K3BA 3KINA 1D1BA 2ZFJA 4ETPA 1MMAA 3X2TA 4BN2A 2VB6A 2FMEA 2X2RA 2G1QA 1VOMA 4BBGA 3DCBA 3WPNA 2NCDA 3WRDA 1FMWA 2FL2A 2X51A 1MKJA 2Y5WA 4Y05A 3B6VA 3CJOA 3ZFDA 1VFWA 3ZCWA 2WOGA 1YRSA 4PJLA 1FMVA 3DC4A 2OWMA 4FRZA 1D0XA 1LVKA 2X7CA 2VASA 4BXNA 4A28A 3GBJA 3NWNA 3PXNA 3KENA 1VFZA 1MMGA 1VFXA 1F9TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GRY A;  1T5C A;  4H1G A;  1BR4 A;  4PK4 A;  5GSZ A;  1BR1 A;  1BR2 A;  2ZFI A;  1Q0B A;  1CZ7 A;  4HNA K;  2FL6 A;  1MMN A;  2VVG A;  1D1C A;  3H4S A;  1GOJ A;  3L1C A;  2ZFL A;  2UYI A;  4PJJ A;  4ZHI A;  4ZCA A;  4A14 A;  1F9W A;  4DBQ A;  3BFN A;  4GKR A;  4E7Z A;  2IEH A;  3K5E A;  3KAR A;  4AS7 A;  2ZFK A;  3HQD A;  5LT3 A;  1F9V A;  2V26 A;  5LT0 A;  1MMD A;  4PJN A;  4UBF A;  4A51 A;  1BG2 A;  1LKX A;  5HLE A;  3COB A;  2XT3 A;  3L9H A;  2MYS A;  2Q2Y A;  1V8J A;  4PFP A;  2XAE A;  4E7S A;  3U06 A;  1N6M A;  2ZFM A;  1X88 A;  3CNZ A;  2FKY A;  1D1A A;  2Y65 A;  1KK7 A;  1D0Y A;  3T0Q A;  1VFV A;  4PJM A;  4A50 A;  5LT2 A;  2KIN A;  4A1Z A;  4LNU K;  1G8X A;  3ZFC A;  4ANJ A;  1I6I A;  4PFO A;  1V8K A;  5LT1 A;  1D0Z A;  2X7E A;  2GM1 A;  4DBR A;  1MNE A;  1SDM A;  2X7D A;  5LT4 A;  2PG2 A;  1RY6 A;  2HEH A;  2Q2Z A;  4AP0 A;  4A5Y A;  1F9U A;  3B6U A;  1II6 A;  4B7B A;  1I5S A;  3LRE A;  2UYM A;  3K3B A;  3KIN A;  1D1B A;  2ZFJ A;  4ETP A;  1MMA A;  3X2T A;  4BN2 A;  2VB6 A;  2FME A;  2X2R A;  2G1Q A;  1VOM A;  4BBG A;  3DCB A;  3WPN A;  2NCD A;  3WRD A;  1FMW A;  2FL2 A;  2X51 A;  1MKJ A;  2Y5W A;  4Y05 A;  3B6V A;  3CJO A;  3ZFD A;  1VFW A;  3ZCW A;  2WOG A;  1YRS A;  4PJL A;  1FMV A;  3DC4 A;  2OWM A;  4FRZ A;  1D0X A;  1LVK A;  2X7C A;  2VAS A;  4BXN A;  4A28 A;  3GBJ A;  3NWN A;  3PXN A;  3KEN A;  1VFZ A;  1MMG A;  1VFX A;  1F9T A; 
#chains in the Genus database with same CATH topology
 2GRY A;  1T5C A;  4H1G A;  1BR4 A;  4PK4 A;  5GSZ A;  1BR1 A;  1BR2 A;  2ZFI A;  1Q0B A;  1CZ7 A;  4HNA K;  2FL6 A;  1MMN A;  2VVG A;  1D1C A;  3H4S A;  2O0A A;  1GOJ A;  3L1C A;  2ZFL A;  2UYI A;  4PJJ A;  4ZHI A;  4ZCA A;  4A14 A;  1F9W A;  4DBQ A;  3BFN A;  4GKR A;  4E7Z A;  2IEH A;  3K5E A;  3KAR A;  4AS7 A;  2ZFK A;  3HQD A;  5LT3 A;  1F9V A;  4GKP A;  2V26 A;  5LT0 A;  1MMD A;  4PJN A;  4UBF A;  4A51 A;  1BG2 A;  1LKX A;  5HLE A;  3COB A;  2XT3 A;  3L9H A;  2MYS A;  2Q2Y A;  1V8J A;  4PFP A;  2XAE A;  4E7S A;  3U06 A;  1N6M A;  2ZFM A;  1X88 A;  3CNZ A;  2FKY A;  1D1A A;  2Y65 A;  1KK7 A;  1D0Y A;  3T0Q A;  1VFV A;  4PJM A;  4A50 A;  5LT2 A;  2KIN A;  4A1Z A;  4LNU K;  1G8X A;  3ZFC A;  4ANJ A;  1I6I A;  4PFO A;  1V8K A;  5LT1 A;  1D0Z A;  2X7E A;  2GM1 A;  4DBR A;  1MNE A;  1SDM A;  2X7D A;  5LT4 A;  2PG2 A;  1RY6 A;  2HEH A;  2Q2Z A;  4AP0 A;  4A5Y A;  1F9U A;  3B6U A;  1II6 A;  4B7B A;  1I5S A;  3LRE A;  2UYM A;  3K3B A;  3KIN A;  1D1B A;  2ZFJ A;  4ETP A;  1MMA A;  3X2T A;  4BN2 A;  2VB6 A;  2FME A;  2X2R A;  2G1Q A;  1VOM A;  4BBG A;  4ETP B;  3DCB A;  3WPN A;  2NCD A;  3WRD A;  1FMW A;  2FL2 A;  2X51 A;  4GKQ A;  1MKJ A;  2Y5W A;  4Y05 A;  3B6V A;  3CJO A;  3ZFD A;  1VFW A;  3ZCW A;  2WOG A;  1YRS A;  4PJL A;  1FMV A;  3DC4 A;  2OWM A;  4FRZ A;  1D0X A;  1LVK A;  2X7C A;  2VAS A;  4BXN A;  4A28 A;  3GBJ A;  3NWN A;  3PXN A;  3KEN A;  1VFZ A;  1MMG A;  1VFX A;  1F9T A; 
#chains in the Genus database with same CATH homology
 2GRY A;  1T5C A;  4H1G A;  1BR4 A;  4PK4 A;  5GSZ A;  1BR1 A;  1BR2 A;  2ZFI A;  1Q0B A;  1CZ7 A;  4HNA K;  2FL6 A;  1MMN A;  2VVG A;  1D1C A;  3H4S A;  1GOJ A;  3L1C A;  2ZFL A;  2UYI A;  4PJJ A;  4ZHI A;  4ZCA A;  4A14 A;  1F9W A;  4DBQ A;  3BFN A;  4GKR A;  4E7Z A;  2IEH A;  3K5E A;  3KAR A;  4AS7 A;  2ZFK A;  3HQD A;  5LT3 A;  1F9V A;  2V26 A;  5LT0 A;  1MMD A;  4PJN A;  4UBF A;  4A51 A;  1BG2 A;  1LKX A;  5HLE A;  3COB A;  2XT3 A;  3L9H A;  2MYS A;  2Q2Y A;  1V8J A;  4PFP A;  2XAE A;  4E7S A;  3U06 A;  1N6M A;  2ZFM A;  1X88 A;  3CNZ A;  2FKY A;  1D1A A;  2Y65 A;  1KK7 A;  1D0Y A;  3T0Q A;  1VFV A;  4PJM A;  4A50 A;  5LT2 A;  2KIN A;  4A1Z A;  4LNU K;  1G8X A;  3ZFC A;  4ANJ A;  1I6I A;  4PFO A;  1V8K A;  5LT1 A;  1D0Z A;  2X7E A;  2GM1 A;  4DBR A;  1MNE A;  1SDM A;  2X7D A;  5LT4 A;  2PG2 A;  1RY6 A;  2HEH A;  2Q2Z A;  4AP0 A;  4A5Y A;  1F9U A;  3B6U A;  1II6 A;  4B7B A;  1I5S A;  3LRE A;  2UYM A;  3K3B A;  3KIN A;  1D1B A;  2ZFJ A;  4ETP A;  1MMA A;  3X2T A;  4BN2 A;  2VB6 A;  2FME A;  2X2R A;  2G1Q A;  1VOM A;  4BBG A;  3DCB A;  3WPN A;  2NCD A;  3WRD A;  1FMW A;  2FL2 A;  2X51 A;  1MKJ A;  2Y5W A;  4Y05 A;  3B6V A;  3CJO A;  3ZFD A;  1VFW A;  3ZCW A;  2WOG A;  1YRS A;  4PJL A;  1FMV A;  3DC4 A;  2OWM A;  4FRZ A;  1D0X A;  1LVK A;  2X7C A;  2VAS A;  4BXN A;  4A28 A;  3GBJ A;  3NWN A;  3PXN A;  3KEN A;  1VFZ A;  1MMG A;  1VFX A;  1F9T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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