1MKJA

Human kinesin motor domain with docked neck linker
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
348
structure length
336
Chain Sequence
b'ADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKE'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords KINESIN HEAVY CHAIN
publication title Two conformations in the human kinesin power stroke defined by X-ray crystallography and EPR spectroscopy.
pubmed rcsb
source organism Homo sapiens
molecule tags Transport protein
total genus 116
structure length 336
sequence length 348
ec nomenclature
pdb deposition date 2002-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 1mkjA00
5LT4A 3DCBA 4ZHIA 1SDMA 3KENA 5LT1A 4LNUK 3ZFDA 4GKRA 1X88A 2KINA 1F9VA 1VFZA 3PXNA 1LKXA 1KK7A 2X2RA 3ZFCA 1N6MA 1GOJA 2PG2A 2Y65A 3COBA 1BR4A 1MMNA 4ETPA 4PFOA 2UYIA 5GSZA 4DBQA 2IEHA 1RY6A 2NCDA 1G8XA 3WPNA 2FKYA 3KINA 2FMEA 1MMAA 4A28A 2ZFMA 2FL6A 5LT3A 4PK4A 5HLEA 3CJOA 3T0QA 1VFVA 1MKJA 2GRYA 3K5EA 2VVGA 2ZFIA 2ZFKA 3KARA 1V8JA 3L9HA 3BFNA 3LREA 4E7SA 4DBRA 1MMDA 4ANJA 3K3BA 4BXNA 2XT3A 3B6UA 1D0ZA 3L1CA 1VOMA 4A50A 2VASA 3CNZA 1BG2A 4AS7A 1LVKA 4UBFA 1BR1A 5LT2A 1T5CA 1BR2A 4E7ZA 2X7CA 1MMGA 3DC4A 4ZCAA 2HEHA 1VFXA 4H1GA 1YRSA 4B7BA 4A14A 3HQDA 1I6IA 2UYMA 1V8KA 2Q2YA 2X7EA 4A51A 2MYSA 1D0YA 2X51A 1F9UA 4BN2A 2OWMA 3X2TA 2ZFJA 5LT0A 1MNEA 3U06A 4A5YA 4Y05A 1FMWA 2Q2ZA 2WOGA 1F9WA 2GM1A 2X7DA 3WRDA 4PJLA 3ZCWA 1I5SA 1D1BA 2VB6A 4BBGA 1II6A 4PFPA 3H4SA 4A1ZA 2ZFLA 3GBJA 3NWNA 1CZ7A 2G1QA 1D1CA 2XAEA 1F9TA 4FRZA 4PJNA 2V26A 2FL2A 1VFWA 1FMVA 4HNAK 3B6VA 1D0XA 4AP0A 2Y5WA 1Q0BA 4PJJA 1D1AA 4PJMA
chains in the Genus database with same CATH superfamily
5LT4A 3DCBA 4ZHIA 1SDMA 3KENA 5LT1A 4LNUK 3ZFDA 4GKRA 1X88A 2KINA 1F9VA 1VFZA 3PXNA 1LKXA 1KK7A 2X2RA 3ZFCA 1N6MA 1GOJA 2PG2A 2Y65A 3COBA 1BR4A 1MMNA 4ETPA 4PFOA 2UYIA 5GSZA 4DBQA 2IEHA 1RY6A 2NCDA 1G8XA 3WPNA 2FKYA 3KINA 4GKPA 2FMEA 1MMAA 4A28A 2ZFMA 2FL6A 5LT3A 4PK4A 5HLEA 3CJOA 3T0QA 1VFVA 1MKJA 2GRYA 3K5EA 2VVGA 2ZFIA 2ZFKA 3KARA 1V8JA 3L9HA 3BFNA 3LREA 4E7SA 4DBRA 1MMDA 4ANJA 3K3BA 4BXNA 2XT3A 3B6UA 1D0ZA 3L1CA 1VOMA 4ETPB 4A50A 2VASA 3CNZA 1BG2A 4AS7A 1LVKA 4UBFA 1BR1A 5LT2A 1T5CA 1BR2A 4E7ZA 2X7CA 2O0AA 1MMGA 3DC4A 4ZCAA 2HEHA 1VFXA 4H1GA 1YRSA 4B7BA 4A14A 3HQDA 1I6IA 2UYMA 1V8KA 2Q2YA 2X7EA 4A51A 2MYSA 1D0YA 2X51A 1F9UA 4BN2A 2OWMA 3X2TA 2ZFJA 5LT0A 1MNEA 3U06A 4A5YA 4Y05A 1FMWA 2Q2ZA 2WOGA 1F9WA 2GM1A 2X7DA 3WRDA 4PJLA 3ZCWA 1I5SA 1D1BA 2VB6A 4BBGA 1II6A 4PFPA 3H4SA 4A1ZA 2ZFLA 3GBJA 4GKQA 3NWNA 1CZ7A 2G1QA 1D1CA 2XAEA 1F9TA 4FRZA 4PJNA 2V26A 2FL2A 1VFWA 1FMVA 4HNAK 3B6VA 1D0XA 4AP0A 2Y5WA 1Q0BA 4PJJA 1D1AA 4PJMA
chains in the Genus database with same CATH topology
5LT4A 3DCBA 4ZHIA 1SDMA 3KENA 5LT1A 4LNUK 3ZFDA 4GKRA 1X88A 2KINA 1F9VA 1VFZA 3PXNA 1LKXA 1KK7A 2X2RA 3ZFCA 1N6MA 1GOJA 2PG2A 2Y65A 3COBA 1BR4A 1MMNA 4ETPA 4PFOA 2UYIA 5GSZA 4DBQA 2IEHA 1RY6A 2NCDA 1G8XA 3WPNA 2FKYA 3KINA 2FMEA 1MMAA 4A28A 2ZFMA 2FL6A 5LT3A 4PK4A 5HLEA 3CJOA 3T0QA 1VFVA 1MKJA 2GRYA 3K5EA 2VVGA 2ZFIA 2ZFKA 3KARA 1V8JA 3L9HA 3BFNA 3LREA 4E7SA 4DBRA 1MMDA 4ANJA 3K3BA 4BXNA 2XT3A 3B6UA 1D0ZA 3L1CA 1VOMA 4A50A 2VASA 3CNZA 1BG2A 4AS7A 1LVKA 4UBFA 1BR1A 5LT2A 1T5CA 1BR2A 4E7ZA 2X7CA 1MMGA 3DC4A 4ZCAA 2HEHA 1VFXA 4H1GA 1YRSA 4B7BA 4A14A 3HQDA 1I6IA 2UYMA 1V8KA 2Q2YA 2X7EA 4A51A 2MYSA 1D0YA 2X51A 1F9UA 4BN2A 2OWMA 3X2TA 2ZFJA 5LT0A 1MNEA 3U06A 4A5YA 4Y05A 1FMWA 2Q2ZA 2WOGA 1F9WA 2GM1A 2X7DA 3WRDA 4PJLA 3ZCWA 1I5SA 1D1BA 2VB6A 4BBGA 1II6A 4PFPA 3H4SA 4A1ZA 2ZFLA 3GBJA 3NWNA 1CZ7A 2G1QA 1D1CA 2XAEA 1F9TA 4FRZA 4PJNA 2V26A 2FL2A 1VFWA 1FMVA 4HNAK 3B6VA 1D0XA 4AP0A 2Y5WA 1Q0BA 4PJJA 1D1AA 4PJMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5LT4 A;  3DCB A;  4ZHI A;  1SDM A;  3KEN A;  5LT1 A;  4LNU K;  3ZFD A;  4GKR A;  1X88 A;  2KIN A;  1F9V A;  1VFZ A;  3PXN A;  1LKX A;  1KK7 A;  2X2R A;  3ZFC A;  1N6M A;  1GOJ A;  2PG2 A;  2Y65 A;  3COB A;  1BR4 A;  1MMN A;  4ETP A;  4PFO A;  2UYI A;  5GSZ A;  4DBQ A;  2IEH A;  1RY6 A;  2NCD A;  1G8X A;  3WPN A;  2FKY A;  3KIN A;  2FME A;  1MMA A;  4A28 A;  2ZFM A;  2FL6 A;  5LT3 A;  4PK4 A;  5HLE A;  3CJO A;  3T0Q A;  1VFV A;  1MKJ A;  2GRY A;  3K5E A;  2VVG A;  2ZFI A;  2ZFK A;  3KAR A;  1V8J A;  3L9H A;  3BFN A;  3LRE A;  4E7S A;  4DBR A;  1MMD A;  4ANJ A;  3K3B A;  4BXN A;  2XT3 A;  3B6U A;  1D0Z A;  3L1C A;  1VOM A;  4A50 A;  2VAS A;  3CNZ A;  1BG2 A;  4AS7 A;  1LVK A;  4UBF A;  1BR1 A;  5LT2 A;  1T5C A;  1BR2 A;  4E7Z A;  2X7C A;  1MMG A;  3DC4 A;  4ZCA A;  2HEH A;  1VFX A;  4H1G A;  1YRS A;  4B7B A;  4A14 A;  3HQD A;  1I6I A;  2UYM A;  1V8K A;  2Q2Y A;  2X7E A;  4A51 A;  2MYS A;  1D0Y A;  2X51 A;  1F9U A;  4BN2 A;  2OWM A;  3X2T A;  2ZFJ A;  5LT0 A;  1MNE A;  3U06 A;  4A5Y A;  4Y05 A;  1FMW A;  2Q2Z A;  2WOG A;  1F9W A;  2GM1 A;  2X7D A;  3WRD A;  4PJL A;  3ZCW A;  1I5S A;  1D1B A;  2VB6 A;  4BBG A;  1II6 A;  4PFP A;  3H4S A;  4A1Z A;  2ZFL A;  3GBJ A;  3NWN A;  1CZ7 A;  2G1Q A;  1D1C A;  2XAE A;  1F9T A;  4FRZ A;  4PJN A;  2V26 A;  2FL2 A;  1VFW A;  1FMV A;  4HNA K;  3B6V A;  1D0X A;  4AP0 A;  2Y5W A;  1Q0B A;  4PJJ A;  1D1A A;  4PJM A; 
#chains in the Genus database with same CATH topology
 5LT4 A;  3DCB A;  4ZHI A;  1SDM A;  3KEN A;  5LT1 A;  4LNU K;  3ZFD A;  4GKR A;  1X88 A;  2KIN A;  1F9V A;  1VFZ A;  3PXN A;  1LKX A;  1KK7 A;  2X2R A;  3ZFC A;  1N6M A;  1GOJ A;  2PG2 A;  2Y65 A;  3COB A;  1BR4 A;  1MMN A;  4ETP A;  4PFO A;  2UYI A;  5GSZ A;  4DBQ A;  2IEH A;  1RY6 A;  2NCD A;  1G8X A;  3WPN A;  2FKY A;  3KIN A;  4GKP A;  2FME A;  1MMA A;  4A28 A;  2ZFM A;  2FL6 A;  5LT3 A;  4PK4 A;  5HLE A;  3CJO A;  3T0Q A;  1VFV A;  1MKJ A;  2GRY A;  3K5E A;  2VVG A;  2ZFI A;  2ZFK A;  3KAR A;  1V8J A;  3L9H A;  3BFN A;  3LRE A;  4E7S A;  4DBR A;  1MMD A;  4ANJ A;  3K3B A;  4BXN A;  2XT3 A;  3B6U A;  1D0Z A;  3L1C A;  1VOM A;  4ETP B;  4A50 A;  2VAS A;  3CNZ A;  1BG2 A;  4AS7 A;  1LVK A;  4UBF A;  1BR1 A;  5LT2 A;  1T5C A;  1BR2 A;  4E7Z A;  2X7C A;  2O0A A;  1MMG A;  3DC4 A;  4ZCA A;  2HEH A;  1VFX A;  4H1G A;  1YRS A;  4B7B A;  4A14 A;  3HQD A;  1I6I A;  2UYM A;  1V8K A;  2Q2Y A;  2X7E A;  4A51 A;  2MYS A;  1D0Y A;  2X51 A;  1F9U A;  4BN2 A;  2OWM A;  3X2T A;  2ZFJ A;  5LT0 A;  1MNE A;  3U06 A;  4A5Y A;  4Y05 A;  1FMW A;  2Q2Z A;  2WOG A;  1F9W A;  2GM1 A;  2X7D A;  3WRD A;  4PJL A;  3ZCW A;  1I5S A;  1D1B A;  2VB6 A;  4BBG A;  1II6 A;  4PFP A;  3H4S A;  4A1Z A;  2ZFL A;  3GBJ A;  4GKQ A;  3NWN A;  1CZ7 A;  2G1Q A;  1D1C A;  2XAE A;  1F9T A;  4FRZ A;  4PJN A;  2V26 A;  2FL2 A;  1VFW A;  1FMV A;  4HNA K;  3B6V A;  1D0X A;  4AP0 A;  2Y5W A;  1Q0B A;  4PJJ A;  1D1A A;  4PJM A; 
#chains in the Genus database with same CATH homology
 5LT4 A;  3DCB A;  4ZHI A;  1SDM A;  3KEN A;  5LT1 A;  4LNU K;  3ZFD A;  4GKR A;  1X88 A;  2KIN A;  1F9V A;  1VFZ A;  3PXN A;  1LKX A;  1KK7 A;  2X2R A;  3ZFC A;  1N6M A;  1GOJ A;  2PG2 A;  2Y65 A;  3COB A;  1BR4 A;  1MMN A;  4ETP A;  4PFO A;  2UYI A;  5GSZ A;  4DBQ A;  2IEH A;  1RY6 A;  2NCD A;  1G8X A;  3WPN A;  2FKY A;  3KIN A;  2FME A;  1MMA A;  4A28 A;  2ZFM A;  2FL6 A;  5LT3 A;  4PK4 A;  5HLE A;  3CJO A;  3T0Q A;  1VFV A;  1MKJ A;  2GRY A;  3K5E A;  2VVG A;  2ZFI A;  2ZFK A;  3KAR A;  1V8J A;  3L9H A;  3BFN A;  3LRE A;  4E7S A;  4DBR A;  1MMD A;  4ANJ A;  3K3B A;  4BXN A;  2XT3 A;  3B6U A;  1D0Z A;  3L1C A;  1VOM A;  4A50 A;  2VAS A;  3CNZ A;  1BG2 A;  4AS7 A;  1LVK A;  4UBF A;  1BR1 A;  5LT2 A;  1T5C A;  1BR2 A;  4E7Z A;  2X7C A;  1MMG A;  3DC4 A;  4ZCA A;  2HEH A;  1VFX A;  4H1G A;  1YRS A;  4B7B A;  4A14 A;  3HQD A;  1I6I A;  2UYM A;  1V8K A;  2Q2Y A;  2X7E A;  4A51 A;  2MYS A;  1D0Y A;  2X51 A;  1F9U A;  4BN2 A;  2OWM A;  3X2T A;  2ZFJ A;  5LT0 A;  1MNE A;  3U06 A;  4A5Y A;  4Y05 A;  1FMW A;  2Q2Z A;  2WOG A;  1F9W A;  2GM1 A;  2X7D A;  3WRD A;  4PJL A;  3ZCW A;  1I5S A;  1D1B A;  2VB6 A;  4BBG A;  1II6 A;  4PFP A;  3H4S A;  4A1Z A;  2ZFL A;  3GBJ A;  3NWN A;  1CZ7 A;  2G1Q A;  1D1C A;  2XAE A;  1F9T A;  4FRZ A;  4PJN A;  2V26 A;  2FL2 A;  1VFW A;  1FMV A;  4HNA K;  3B6V A;  1D0X A;  4AP0 A;  2Y5W A;  1Q0B A;  4PJJ A;  1D1A A;  4PJM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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