2HEHA

Crystal structure of the kif2c motor domain
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
359
structure length
324
Chain Sequence
NWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGKGIYAMASRDVFLLKNQPCYRKLGLEVYVTFFEIYNGKLFDLLNKKAKLRVLEDGKQQVQVVGLQEHLVNSADDVIKMIDMGSACRNSSRSHACFQIILRAKGRMHGKFSLVDLAGNEGAEINKSLLALKECIRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIATISPGISSCEYTLNTLRYADRVKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords KIF2C protein
publication title Crystal structure of the kif2c motor domain
rcsb
source organism Homo sapiens
molecule tags Structural genomics, structural protein
total genus 107
structure length 324
sequence length 359
ec nomenclature
pdb deposition date 2006-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 2hehA00
1VFZA 1X88A 1V8JA 2GM1A 3PXNA 5LT4A 1RY6A 2Y65A 1F9VA 3L9HA 3B6UA 2OWMA 1F9WA 2X7EA 1GOJA 4E7ZA 2FMEA 4PK4A 1LVKA 4BBGA 3KENA 1BG2A 4DBRA 2UYMA 3WPNA 3LREA 4PFPA 4DBQA 1D1BA 3B6VA 1F9TA 2KINA 1D1CA 1G8XA 2PG2A 2IEHA 4ZCAA 5HLEA 1MMAA 1MMGA 2Q2ZA 1T5CA 2V26A 1D1AA 1BR1A 4LNUK 4A51A 4Y05A 4H1GA 4B7BA 4A28A 1KK7A 2ZFKA 4GKRA 3NWNA 1Q0BA 3ZCWA 2X51A 4A14A 4AP0A 3U06A 4HNAK 2XT3A 3KARA 4PJJA 2X7DA 4ANJA 3CNZA 3X2TA 3KINA 1MMDA 1D0XA 5LT0A 4PJLA 1VFXA 1FMWA 2X2RA 2VASA 3H4SA 2X7CA 3L1CA 1MKJA 1V8KA 1CZ7A 2ZFIA 1II6A 5LT2A 2FKYA 3WRDA 4UBFA 2HEHA 2XAEA 1VOMA 4PJMA 4BN2A 3DCBA 5LT1A 4E7SA 2MYSA 2ZFMA 4FRZA 1SDMA 2GRYA 2FL6A 4A5YA 1I6IA 2ZFLA 3BFNA 3GBJA 3T0QA 2NCDA 1YRSA 1N6MA 4A1ZA 1D0YA 2Y5WA 1LKXA 1VFVA 4ZHIA 1D0ZA 1BR4A 2UYIA 3COBA 1MMNA 2Q2YA 3ZFCA 4BXNA 2VB6A 1VFWA 4A50A 5GSZA 1I5SA 4PJNA 5LT3A 2VVGA 2G1QA 1MNEA 2WOGA 3DC4A 3ZFDA 3K5EA 3HQDA 1BR2A 2ZFJA 3K3BA 3CJOA 1FMVA 4ETPA 4AS7A 4PFOA 2FL2A 1F9UA
chains in the Genus database with same CATH superfamily
1VFZA 1X88A 1V8JA 2GM1A 3PXNA 5LT4A 1RY6A 2Y65A 1F9VA 3L9HA 3B6UA 2OWMA 1F9WA 2X7EA 1GOJA 4E7ZA 2FMEA 4PK4A 1LVKA 4BBGA 3KENA 1BG2A 4DBRA 2UYMA 3WPNA 3LREA 4PFPA 4DBQA 1D1BA 3B6VA 1F9TA 2KINA 1D1CA 1G8XA 2PG2A 2IEHA 4ZCAA 4ETPB 5HLEA 1MMAA 1MMGA 2Q2ZA 1T5CA 2V26A 1D1AA 1BR1A 4LNUK 4A51A 4Y05A 4GKQA 4H1GA 4B7BA 4A28A 1KK7A 2ZFKA 4GKRA 3NWNA 1Q0BA 3ZCWA 2X51A 4A14A 4AP0A 3U06A 4HNAK 2XT3A 3KARA 4PJJA 2X7DA 4ANJA 3CNZA 3X2TA 3KINA 1MMDA 1D0XA 5LT0A 4PJLA 1VFXA 1FMWA 2X2RA 2VASA 3H4SA 2X7CA 3L1CA 1MKJA 1V8KA 1CZ7A 2ZFIA 1II6A 5LT2A 2FKYA 3WRDA 4UBFA 2HEHA 2XAEA 1VOMA 4PJMA 4BN2A 3DCBA 5LT1A 4E7SA 2MYSA 2ZFMA 4FRZA 1SDMA 2GRYA 2O0AA 2FL6A 4A5YA 1I6IA 2ZFLA 3BFNA 3GBJA 3T0QA 2NCDA 1YRSA 1N6MA 4A1ZA 1D0YA 2Y5WA 1LKXA 1VFVA 4ZHIA 1D0ZA 1BR4A 2UYIA 3COBA 1MMNA 2Q2YA 3ZFCA 4BXNA 2VB6A 1VFWA 4A50A 5GSZA 1I5SA 4PJNA 5LT3A 2VVGA 2G1QA 1MNEA 2WOGA 3DC4A 3ZFDA 3K5EA 3HQDA 1BR2A 2ZFJA 3K3BA 3CJOA 1FMVA 4GKPA 4AS7A 4ETPA 4PFOA 2FL2A 1F9UA
chains in the Genus database with same CATH topology
1VFZA 1X88A 1V8JA 2GM1A 3PXNA 5LT4A 1RY6A 2Y65A 1F9VA 3L9HA 3B6UA 2OWMA 1F9WA 2X7EA 1GOJA 4E7ZA 2FMEA 4PK4A 1LVKA 4BBGA 3KENA 1BG2A 4DBRA 2UYMA 3WPNA 3LREA 4PFPA 4DBQA 1D1BA 3B6VA 1F9TA 2KINA 1D1CA 1G8XA 2PG2A 2IEHA 4ZCAA 5HLEA 1MMAA 1MMGA 2Q2ZA 1T5CA 2V26A 1D1AA 1BR1A 4LNUK 4A51A 4Y05A 4H1GA 4B7BA 4A28A 1KK7A 2ZFKA 4GKRA 3NWNA 1Q0BA 3ZCWA 2X51A 4A14A 4AP0A 3U06A 4HNAK 2XT3A 3KARA 4PJJA 2X7DA 4ANJA 3CNZA 3X2TA 3KINA 1MMDA 1D0XA 5LT0A 4PJLA 1VFXA 1FMWA 2X2RA 2VASA 3H4SA 2X7CA 3L1CA 1MKJA 1V8KA 1CZ7A 2ZFIA 1II6A 5LT2A 2FKYA 3WRDA 4UBFA 2HEHA 2XAEA 1VOMA 4PJMA 4BN2A 3DCBA 5LT1A 4E7SA 2MYSA 2ZFMA 4FRZA 1SDMA 2GRYA 2FL6A 4A5YA 1I6IA 2ZFLA 3BFNA 3GBJA 3T0QA 2NCDA 1YRSA 1N6MA 4A1ZA 1D0YA 2Y5WA 1LKXA 1VFVA 4ZHIA 1D0ZA 1BR4A 2UYIA 3COBA 1MMNA 2Q2YA 3ZFCA 4BXNA 2VB6A 1VFWA 4A50A 5GSZA 1I5SA 4PJNA 5LT3A 2VVGA 2G1QA 1MNEA 2WOGA 3DC4A 3ZFDA 3K5EA 3HQDA 1BR2A 2ZFJA 3K3BA 3CJOA 1FMVA 4ETPA 4AS7A 4PFOA 2FL2A 1F9UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VFZ A;  1X88 A;  1V8J A;  2GM1 A;  3PXN A;  5LT4 A;  1RY6 A;  2Y65 A;  1F9V A;  3L9H A;  3B6U A;  2OWM A;  1F9W A;  2X7E A;  1GOJ A;  4E7Z A;  2FME A;  4PK4 A;  1LVK A;  4BBG A;  3KEN A;  1BG2 A;  4DBR A;  2UYM A;  3WPN A;  3LRE A;  4PFP A;  4DBQ A;  1D1B A;  3B6V A;  1F9T A;  2KIN A;  1D1C A;  1G8X A;  2PG2 A;  2IEH A;  4ZCA A;  5HLE A;  1MMA A;  1MMG A;  2Q2Z A;  1T5C A;  2V26 A;  1D1A A;  1BR1 A;  4LNU K;  4A51 A;  4Y05 A;  4H1G A;  4B7B A;  4A28 A;  1KK7 A;  2ZFK A;  4GKR A;  3NWN A;  1Q0B A;  3ZCW A;  2X51 A;  4A14 A;  4AP0 A;  3U06 A;  4HNA K;  2XT3 A;  3KAR A;  4PJJ A;  2X7D A;  4ANJ A;  3CNZ A;  3X2T A;  3KIN A;  1MMD A;  1D0X A;  5LT0 A;  4PJL A;  1VFX A;  1FMW A;  2X2R A;  2VAS A;  3H4S A;  2X7C A;  3L1C A;  1MKJ A;  1V8K A;  1CZ7 A;  2ZFI A;  1II6 A;  5LT2 A;  2FKY A;  3WRD A;  4UBF A;  2HEH A;  2XAE A;  1VOM A;  4PJM A;  4BN2 A;  3DCB A;  5LT1 A;  4E7S A;  2MYS A;  2ZFM A;  4FRZ A;  1SDM A;  2GRY A;  2FL6 A;  4A5Y A;  1I6I A;  2ZFL A;  3BFN A;  3GBJ A;  3T0Q A;  2NCD A;  1YRS A;  1N6M A;  4A1Z A;  1D0Y A;  2Y5W A;  1LKX A;  1VFV A;  4ZHI A;  1D0Z A;  1BR4 A;  2UYI A;  3COB A;  1MMN A;  2Q2Y A;  3ZFC A;  4BXN A;  2VB6 A;  1VFW A;  4A50 A;  5GSZ A;  1I5S A;  4PJN A;  5LT3 A;  2VVG A;  2G1Q A;  1MNE A;  2WOG A;  3DC4 A;  3ZFD A;  3K5E A;  3HQD A;  1BR2 A;  2ZFJ A;  3K3B A;  3CJO A;  1FMV A;  4ETP A;  4AS7 A;  4PFO A;  2FL2 A;  1F9U A; 
#chains in the Genus database with same CATH topology
 1VFZ A;  1X88 A;  1V8J A;  2GM1 A;  3PXN A;  5LT4 A;  1RY6 A;  2Y65 A;  1F9V A;  3L9H A;  3B6U A;  2OWM A;  1F9W A;  2X7E A;  1GOJ A;  4E7Z A;  2FME A;  4PK4 A;  1LVK A;  4BBG A;  3KEN A;  1BG2 A;  4DBR A;  2UYM A;  3WPN A;  3LRE A;  4PFP A;  4DBQ A;  1D1B A;  3B6V A;  1F9T A;  2KIN A;  1D1C A;  1G8X A;  2PG2 A;  2IEH A;  4ZCA A;  4ETP B;  5HLE A;  1MMA A;  1MMG A;  2Q2Z A;  1T5C A;  2V26 A;  1D1A A;  1BR1 A;  4LNU K;  4A51 A;  4Y05 A;  4GKQ A;  4H1G A;  4B7B A;  4A28 A;  1KK7 A;  2ZFK A;  4GKR A;  3NWN A;  1Q0B A;  3ZCW A;  2X51 A;  4A14 A;  4AP0 A;  3U06 A;  4HNA K;  2XT3 A;  3KAR A;  4PJJ A;  2X7D A;  4ANJ A;  3CNZ A;  3X2T A;  3KIN A;  1MMD A;  1D0X A;  5LT0 A;  4PJL A;  1VFX A;  1FMW A;  2X2R A;  2VAS A;  3H4S A;  2X7C A;  3L1C A;  1MKJ A;  1V8K A;  1CZ7 A;  2ZFI A;  1II6 A;  5LT2 A;  2FKY A;  3WRD A;  4UBF A;  2HEH A;  2XAE A;  1VOM A;  4PJM A;  4BN2 A;  3DCB A;  5LT1 A;  4E7S A;  2MYS A;  2ZFM A;  4FRZ A;  1SDM A;  2GRY A;  2O0A A;  2FL6 A;  4A5Y A;  1I6I A;  2ZFL A;  3BFN A;  3GBJ A;  3T0Q A;  2NCD A;  1YRS A;  1N6M A;  4A1Z A;  1D0Y A;  2Y5W A;  1LKX A;  1VFV A;  4ZHI A;  1D0Z A;  1BR4 A;  2UYI A;  3COB A;  1MMN A;  2Q2Y A;  3ZFC A;  4BXN A;  2VB6 A;  1VFW A;  4A50 A;  5GSZ A;  1I5S A;  4PJN A;  5LT3 A;  2VVG A;  2G1Q A;  1MNE A;  2WOG A;  3DC4 A;  3ZFD A;  3K5E A;  3HQD A;  1BR2 A;  2ZFJ A;  3K3B A;  3CJO A;  1FMV A;  4GKP A;  4AS7 A;  4ETP A;  4PFO A;  2FL2 A;  1F9U A; 
#chains in the Genus database with same CATH homology
 1VFZ A;  1X88 A;  1V8J A;  2GM1 A;  3PXN A;  5LT4 A;  1RY6 A;  2Y65 A;  1F9V A;  3L9H A;  3B6U A;  2OWM A;  1F9W A;  2X7E A;  1GOJ A;  4E7Z A;  2FME A;  4PK4 A;  1LVK A;  4BBG A;  3KEN A;  1BG2 A;  4DBR A;  2UYM A;  3WPN A;  3LRE A;  4PFP A;  4DBQ A;  1D1B A;  3B6V A;  1F9T A;  2KIN A;  1D1C A;  1G8X A;  2PG2 A;  2IEH A;  4ZCA A;  5HLE A;  1MMA A;  1MMG A;  2Q2Z A;  1T5C A;  2V26 A;  1D1A A;  1BR1 A;  4LNU K;  4A51 A;  4Y05 A;  4H1G A;  4B7B A;  4A28 A;  1KK7 A;  2ZFK A;  4GKR A;  3NWN A;  1Q0B A;  3ZCW A;  2X51 A;  4A14 A;  4AP0 A;  3U06 A;  4HNA K;  2XT3 A;  3KAR A;  4PJJ A;  2X7D A;  4ANJ A;  3CNZ A;  3X2T A;  3KIN A;  1MMD A;  1D0X A;  5LT0 A;  4PJL A;  1VFX A;  1FMW A;  2X2R A;  2VAS A;  3H4S A;  2X7C A;  3L1C A;  1MKJ A;  1V8K A;  1CZ7 A;  2ZFI A;  1II6 A;  5LT2 A;  2FKY A;  3WRD A;  4UBF A;  2HEH A;  2XAE A;  1VOM A;  4PJM A;  4BN2 A;  3DCB A;  5LT1 A;  4E7S A;  2MYS A;  2ZFM A;  4FRZ A;  1SDM A;  2GRY A;  2FL6 A;  4A5Y A;  1I6I A;  2ZFL A;  3BFN A;  3GBJ A;  3T0Q A;  2NCD A;  1YRS A;  1N6M A;  4A1Z A;  1D0Y A;  2Y5W A;  1LKX A;  1VFV A;  4ZHI A;  1D0Z A;  1BR4 A;  2UYI A;  3COB A;  1MMN A;  2Q2Y A;  3ZFC A;  4BXN A;  2VB6 A;  1VFW A;  4A50 A;  5GSZ A;  1I5S A;  4PJN A;  5LT3 A;  2VVG A;  2G1Q A;  1MNE A;  2WOG A;  3DC4 A;  3ZFD A;  3K5E A;  3HQD A;  1BR2 A;  2ZFJ A;  3K3B A;  3CJO A;  1FMV A;  4ETP A;  4AS7 A;  4PFO A;  2FL2 A;  1F9U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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