2HEHA

Crystal structure of the kif2c motor domain
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
359
structure length
324
Chain Sequence
NWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGKGIYAMASRDVFLLKNQPCYRKLGLEVYVTFFEIYNGKLFDLLNKKAKLRVLEDGKQQVQVVGLQEHLVNSADDVIKMIDMGSACRNSSRSHACFQIILRAKGRMHGKFSLVDLAGNEGAEINKSLLALKECIRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIATISPGISSCEYTLNTLRYADRVKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the kif2c motor domain
rcsb
molecule tags Structural genomics, structural protein
source organism Homo sapiens
molecule keywords KIF2C protein
total genus 107
structure length 324
sequence length 359
ec nomenclature
pdb deposition date 2006-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 2hehA00
1MMNA 2KINA 4A5YA 4A51A 3DCBA 2OWMA 1LVKA 2IEHA 1MKJA 4PJNA 1BG2A 4PFPA 4FRZA 2ZFKA 3BFNA 1D0YA 2G1QA 3X2TA 4PFOA 1VFZA 3B6UA 4PJJA 3ZFCA 2GRYA 5HLEA 2X7DA 4HNAK 1VFWA 2VB6A 1BR2A 1I6IA 2ZFLA 1F9TA 3COBA 2FMEA 4E7SA 4E7ZA 2ZFJA 2V26A 2VASA 2FL2A 1KK7A 5LT0A 5LT2A 1V8JA 3GBJA 1D0ZA 4ANJA 3WPNA 1F9WA 2X51A 2XT3A 3ZFDA 1MMDA 3WRDA 4A1ZA 1Q0BA 1D1CA 2GM1A 4ZCAA 1N6MA 1V8KA 1VFXA 1G8XA 2X2RA 3K3BA 2MYSA 1SDMA 1D1AA 4H1GA 4DBRA 2X7EA 4GKRA 1D1BA 2Y5WA 4PK4A 4B7BA 2X7CA 4AP0A 3K5EA 2HEHA 2XAEA 3KARA 3CJOA 3U06A 3LREA 3H4SA 1F9UA 4A50A 1T5CA 2ZFMA 1BR4A 1FMWA 2WOGA 4DBQA 5LT4A 4Y05A 4BBGA 2ZFIA 2FKYA 1YRSA 3NWNA 1D0XA 3KENA 4AS7A 1GOJA 2UYIA 5LT1A 2VVGA 3L9HA 4A28A 2Q2ZA 4A14A 4BN2A 2NCDA 5LT3A 4ETPA 1MMAA 1MNEA 3B6VA 1X88A 3T0QA 1VFVA 2Q2YA 1I5SA 3ZCWA 1LKXA 1RY6A 1FMVA 1VOMA 4ZHIA 4PJMA 5GSZA 4BXNA 3CNZA 3PXNA 3DC4A 2FL6A 3L1CA 1MMGA 1CZ7A 4UBFA 3HQDA 4PJLA 3KINA 2UYMA 1BR1A 1II6A 2Y65A 1F9VA 4LNUK 2PG2A
chains in the Genus database with same CATH superfamily
1MMNA 2KINA 4A5YA 4A51A 3DCBA 2OWMA 1LVKA 2IEHA 1MKJA 4PJNA 1BG2A 4PFPA 4FRZA 2ZFKA 3BFNA 1D0YA 2G1QA 3X2TA 4PFOA 1VFZA 3B6UA 2O0AA 4PJJA 3ZFCA 2GRYA 5HLEA 2X7DA 4HNAK 1VFWA 2VB6A 1BR2A 1I6IA 2ZFLA 1F9TA 3COBA 2FMEA 4GKPA 4E7SA 4E7ZA 2ZFJA 2V26A 4ETPB 2VASA 2FL2A 1KK7A 5LT0A 5LT2A 1V8JA 3GBJA 1D0ZA 4ANJA 3WPNA 1F9WA 2X51A 2XT3A 3ZFDA 1MMDA 3WRDA 4A1ZA 1Q0BA 1D1CA 2GM1A 4ZCAA 1N6MA 1V8KA 1VFXA 1G8XA 2X2RA 3K3BA 2MYSA 1SDMA 1D1AA 4H1GA 4DBRA 2X7EA 4GKRA 1D1BA 2Y5WA 4PK4A 4B7BA 2X7CA 4AP0A 3K5EA 2HEHA 2XAEA 3KARA 3CJOA 3U06A 3LREA 3H4SA 1F9UA 4A50A 1T5CA 2ZFMA 1BR4A 1FMWA 2WOGA 4DBQA 5LT4A 4Y05A 4BBGA 2ZFIA 2FKYA 1YRSA 3NWNA 1D0XA 3KENA 4AS7A 1GOJA 2UYIA 5LT1A 2VVGA 3L9HA 4A28A 2Q2ZA 4A14A 4BN2A 2NCDA 5LT3A 4ETPA 1MMAA 1MNEA 3B6VA 1X88A 3T0QA 1VFVA 2Q2YA 1I5SA 3ZCWA 1LKXA 1RY6A 1FMVA 1VOMA 4GKQA 4PJMA 4ZHIA 5GSZA 4BXNA 3CNZA 3PXNA 3DC4A 2FL6A 3L1CA 1MMGA 1CZ7A 4UBFA 3HQDA 4PJLA 3KINA 2UYMA 1BR1A 1II6A 2Y65A 1F9VA 4LNUK 2PG2A
chains in the Genus database with same CATH topology
1MMNA 2KINA 4A5YA 4A51A 3DCBA 2OWMA 1LVKA 2IEHA 1MKJA 4PJNA 1BG2A 4PFPA 4FRZA 2ZFKA 3BFNA 1D0YA 2G1QA 3X2TA 4PFOA 1VFZA 3B6UA 4PJJA 3ZFCA 2GRYA 5HLEA 2X7DA 4HNAK 1VFWA 2VB6A 1BR2A 1I6IA 2ZFLA 1F9TA 3COBA 2FMEA 4E7SA 4E7ZA 2ZFJA 2V26A 2VASA 2FL2A 1KK7A 5LT0A 5LT2A 1V8JA 3GBJA 1D0ZA 4ANJA 3WPNA 1F9WA 2X51A 2XT3A 3ZFDA 1MMDA 3WRDA 4A1ZA 1Q0BA 1D1CA 2GM1A 4ZCAA 1N6MA 1V8KA 1VFXA 1G8XA 2X2RA 3K3BA 2MYSA 1SDMA 1D1AA 4H1GA 4DBRA 2X7EA 4GKRA 1D1BA 2Y5WA 4PK4A 4B7BA 2X7CA 4AP0A 3K5EA 2HEHA 2XAEA 3KARA 3CJOA 3U06A 3LREA 3H4SA 1F9UA 4A50A 1T5CA 2ZFMA 1BR4A 1FMWA 2WOGA 4DBQA 5LT4A 4Y05A 4BBGA 2ZFIA 2FKYA 1YRSA 3NWNA 1D0XA 3KENA 4AS7A 1GOJA 2UYIA 5LT1A 2VVGA 3L9HA 4A28A 2Q2ZA 4A14A 4BN2A 2NCDA 5LT3A 4ETPA 1MMAA 1MNEA 3B6VA 1X88A 3T0QA 1VFVA 2Q2YA 1I5SA 3ZCWA 1LKXA 1RY6A 1FMVA 1VOMA 4ZHIA 4PJMA 5GSZA 4BXNA 3CNZA 3PXNA 3DC4A 2FL6A 3L1CA 1MMGA 1CZ7A 4UBFA 3HQDA 4PJLA 3KINA 2UYMA 1BR1A 1II6A 2Y65A 1F9VA 4LNUK 2PG2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MMN A;  2KIN A;  4A5Y A;  4A51 A;  3DCB A;  2OWM A;  1LVK A;  2IEH A;  1MKJ A;  4PJN A;  1BG2 A;  4PFP A;  4FRZ A;  2ZFK A;  3BFN A;  1D0Y A;  2G1Q A;  3X2T A;  4PFO A;  1VFZ A;  3B6U A;  4PJJ A;  3ZFC A;  2GRY A;  5HLE A;  2X7D A;  4HNA K;  1VFW A;  2VB6 A;  1BR2 A;  1I6I A;  2ZFL A;  1F9T A;  3COB A;  2FME A;  4E7S A;  4E7Z A;  2ZFJ A;  2V26 A;  2VAS A;  2FL2 A;  1KK7 A;  5LT0 A;  5LT2 A;  1V8J A;  3GBJ A;  1D0Z A;  4ANJ A;  3WPN A;  1F9W A;  2X51 A;  2XT3 A;  3ZFD A;  1MMD A;  3WRD A;  4A1Z A;  1Q0B A;  1D1C A;  2GM1 A;  4ZCA A;  1N6M A;  1V8K A;  1VFX A;  1G8X A;  2X2R A;  3K3B A;  2MYS A;  1SDM A;  1D1A A;  4H1G A;  4DBR A;  2X7E A;  4GKR A;  1D1B A;  2Y5W A;  4PK4 A;  4B7B A;  2X7C A;  4AP0 A;  3K5E A;  2HEH A;  2XAE A;  3KAR A;  3CJO A;  3U06 A;  3LRE A;  3H4S A;  1F9U A;  4A50 A;  1T5C A;  2ZFM A;  1BR4 A;  1FMW A;  2WOG A;  4DBQ A;  5LT4 A;  4Y05 A;  4BBG A;  2ZFI A;  2FKY A;  1YRS A;  3NWN A;  1D0X A;  3KEN A;  4AS7 A;  1GOJ A;  2UYI A;  5LT1 A;  2VVG A;  3L9H A;  4A28 A;  2Q2Z A;  4A14 A;  4BN2 A;  2NCD A;  5LT3 A;  4ETP A;  1MMA A;  1MNE A;  3B6V A;  1X88 A;  3T0Q A;  1VFV A;  2Q2Y A;  1I5S A;  3ZCW A;  1LKX A;  1RY6 A;  1FMV A;  1VOM A;  4ZHI A;  4PJM A;  5GSZ A;  4BXN A;  3CNZ A;  3PXN A;  3DC4 A;  2FL6 A;  3L1C A;  1MMG A;  1CZ7 A;  4UBF A;  3HQD A;  4PJL A;  3KIN A;  2UYM A;  1BR1 A;  1II6 A;  2Y65 A;  1F9V A;  4LNU K;  2PG2 A; 
#chains in the Genus database with same CATH topology
 1MMN A;  2KIN A;  4A5Y A;  4A51 A;  3DCB A;  2OWM A;  1LVK A;  2IEH A;  1MKJ A;  4PJN A;  1BG2 A;  4PFP A;  4FRZ A;  2ZFK A;  3BFN A;  1D0Y A;  2G1Q A;  3X2T A;  4PFO A;  1VFZ A;  3B6U A;  2O0A A;  4PJJ A;  3ZFC A;  2GRY A;  5HLE A;  2X7D A;  4HNA K;  1VFW A;  2VB6 A;  1BR2 A;  1I6I A;  2ZFL A;  1F9T A;  3COB A;  2FME A;  4GKP A;  4E7S A;  4E7Z A;  2ZFJ A;  2V26 A;  4ETP B;  2VAS A;  2FL2 A;  1KK7 A;  5LT0 A;  5LT2 A;  1V8J A;  3GBJ A;  1D0Z A;  4ANJ A;  3WPN A;  1F9W A;  2X51 A;  2XT3 A;  3ZFD A;  1MMD A;  3WRD A;  4A1Z A;  1Q0B A;  1D1C A;  2GM1 A;  4ZCA A;  1N6M A;  1V8K A;  1VFX A;  1G8X A;  2X2R A;  3K3B A;  2MYS A;  1SDM A;  1D1A A;  4H1G A;  4DBR A;  2X7E A;  4GKR A;  1D1B A;  2Y5W A;  4PK4 A;  4B7B A;  2X7C A;  4AP0 A;  3K5E A;  2HEH A;  2XAE A;  3KAR A;  3CJO A;  3U06 A;  3LRE A;  3H4S A;  1F9U A;  4A50 A;  1T5C A;  2ZFM A;  1BR4 A;  1FMW A;  2WOG A;  4DBQ A;  5LT4 A;  4Y05 A;  4BBG A;  2ZFI A;  2FKY A;  1YRS A;  3NWN A;  1D0X A;  3KEN A;  4AS7 A;  1GOJ A;  2UYI A;  5LT1 A;  2VVG A;  3L9H A;  4A28 A;  2Q2Z A;  4A14 A;  4BN2 A;  2NCD A;  5LT3 A;  4ETP A;  1MMA A;  1MNE A;  3B6V A;  1X88 A;  3T0Q A;  1VFV A;  2Q2Y A;  1I5S A;  3ZCW A;  1LKX A;  1RY6 A;  1FMV A;  1VOM A;  4GKQ A;  4PJM A;  4ZHI A;  5GSZ A;  4BXN A;  3CNZ A;  3PXN A;  3DC4 A;  2FL6 A;  3L1C A;  1MMG A;  1CZ7 A;  4UBF A;  3HQD A;  4PJL A;  3KIN A;  2UYM A;  1BR1 A;  1II6 A;  2Y65 A;  1F9V A;  4LNU K;  2PG2 A; 
#chains in the Genus database with same CATH homology
 1MMN A;  2KIN A;  4A5Y A;  4A51 A;  3DCB A;  2OWM A;  1LVK A;  2IEH A;  1MKJ A;  4PJN A;  1BG2 A;  4PFP A;  4FRZ A;  2ZFK A;  3BFN A;  1D0Y A;  2G1Q A;  3X2T A;  4PFO A;  1VFZ A;  3B6U A;  4PJJ A;  3ZFC A;  2GRY A;  5HLE A;  2X7D A;  4HNA K;  1VFW A;  2VB6 A;  1BR2 A;  1I6I A;  2ZFL A;  1F9T A;  3COB A;  2FME A;  4E7S A;  4E7Z A;  2ZFJ A;  2V26 A;  2VAS A;  2FL2 A;  1KK7 A;  5LT0 A;  5LT2 A;  1V8J A;  3GBJ A;  1D0Z A;  4ANJ A;  3WPN A;  1F9W A;  2X51 A;  2XT3 A;  3ZFD A;  1MMD A;  3WRD A;  4A1Z A;  1Q0B A;  1D1C A;  2GM1 A;  4ZCA A;  1N6M A;  1V8K A;  1VFX A;  1G8X A;  2X2R A;  3K3B A;  2MYS A;  1SDM A;  1D1A A;  4H1G A;  4DBR A;  2X7E A;  4GKR A;  1D1B A;  2Y5W A;  4PK4 A;  4B7B A;  2X7C A;  4AP0 A;  3K5E A;  2HEH A;  2XAE A;  3KAR A;  3CJO A;  3U06 A;  3LRE A;  3H4S A;  1F9U A;  4A50 A;  1T5C A;  2ZFM A;  1BR4 A;  1FMW A;  2WOG A;  4DBQ A;  5LT4 A;  4Y05 A;  4BBG A;  2ZFI A;  2FKY A;  1YRS A;  3NWN A;  1D0X A;  3KEN A;  4AS7 A;  1GOJ A;  2UYI A;  5LT1 A;  2VVG A;  3L9H A;  4A28 A;  2Q2Z A;  4A14 A;  4BN2 A;  2NCD A;  5LT3 A;  4ETP A;  1MMA A;  1MNE A;  3B6V A;  1X88 A;  3T0Q A;  1VFV A;  2Q2Y A;  1I5S A;  3ZCW A;  1LKX A;  1RY6 A;  1FMV A;  1VOM A;  4ZHI A;  4PJM A;  5GSZ A;  4BXN A;  3CNZ A;  3PXN A;  3DC4 A;  2FL6 A;  3L1C A;  1MMG A;  1CZ7 A;  4UBF A;  3HQD A;  4PJL A;  3KIN A;  2UYM A;  1BR1 A;  1II6 A;  2Y65 A;  1F9V A;  4LNU K;  2PG2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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