4ZCAA

Eg5 motor domain mutant y231f
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
350
structure length
334
Chain Sequence
GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAFSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSERAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Eg5
rcsb
molecule tags Motor protein
source organism Homo sapiens
molecule keywords Kinesin-like protein KIF11
total genus 101
structure length 334
sequence length 350
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-04-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 4zcaA00
3KARA 4PFOA 3L1CA 1D0ZA 2IEHA 1Q0BA 3ZFDA 5LT2A 1MMGA 1GOJA 1KK7A 4PJNA 2ZFIA 5HLEA 1D1BA 4AP0A 1F9WA 3DCBA 1VFVA 1F9TA 4Y05A 1VFZA 3K5EA 1MMAA 2UYIA 4BBGA 5LT1A 2ZFLA 3L9HA 1YRSA 3HQDA 1I6IA 4DBQA 3LREA 3COBA 1D1AA 1F9UA 4H1GA 4PJMA 2G1QA 2FKYA 3WPNA 2OWMA 4A14A 2PG2A 3ZFCA 1VOMA 4HNAK 1RY6A 2X7DA 1VFXA 3BFNA 3KENA 4BN2A 3B6VA 2XT3A 2V26A 2VASA 4ZHIA 3B6UA 1T5CA 3K3BA 4ZCAA 2MYSA 3CJOA 4E7SA 5LT0A 1G8XA 1I5SA 4UBFA 3H4SA 1N6MA 2XAEA 4FRZA 1D0XA 4A5YA 4PJLA 1II6A 1F9VA 4BXNA 2X2RA 2HEHA 2VB6A 2GM1A 2Q2YA 2FL2A 2ZFKA 3DC4A 4PJJA 4LNUK 1FMWA 3ZCWA 4A51A 2GRYA 2X51A 3PXNA 1LKXA 2FL6A 1D0YA 1X88A 4B7BA 1D1CA 1SDMA 1V8KA 4PK4A 2ZFMA 1VFWA 2Y5WA 3T0QA 1BG2A 4PFPA 1MKJA 2VVGA 4ETPA 1MMDA 1MMNA 4E7ZA 2NCDA 3U06A 2UYMA 1FMVA 2X7EA 2X7CA 3X2TA 2Y65A 1BR1A 3CNZA 3GBJA 3NWNA 4GKRA 5LT3A 2ZFJA 3KINA 2Q2ZA 5GSZA 4A28A 1BR2A 4A1ZA 1LVKA 4AS7A 4DBRA 1BR4A 2FMEA 2WOGA 4ANJA 5LT4A 4A50A 1CZ7A 1MNEA 1V8JA 3WRDA 2KINA
chains in the Genus database with same CATH superfamily
3KARA 4PFOA 3L1CA 1D0ZA 2IEHA 1Q0BA 3ZFDA 5LT2A 1MMGA 1GOJA 1KK7A 4PJNA 2ZFIA 5HLEA 1D1BA 4AP0A 1F9WA 3DCBA 1VFVA 1F9TA 4Y05A 1VFZA 3K5EA 1MMAA 2UYIA 4BBGA 5LT1A 2ZFLA 3L9HA 1YRSA 3HQDA 1I6IA 4GKPA 4DBQA 3LREA 3COBA 1D1AA 1F9UA 4H1GA 4PJMA 2G1QA 4GKQA 2FKYA 3WPNA 2OWMA 4A14A 2PG2A 3ZFCA 1VOMA 4HNAK 1RY6A 2X7DA 1VFXA 3BFNA 3KENA 4BN2A 4ETPB 3B6VA 2XT3A 2V26A 2VASA 4ZHIA 3B6UA 1T5CA 3K3BA 4ZCAA 2MYSA 3CJOA 4E7SA 5LT0A 1G8XA 1I5SA 4UBFA 3H4SA 1N6MA 2XAEA 4FRZA 1D0XA 4A5YA 4PJLA 1II6A 1F9VA 4BXNA 2X2RA 2HEHA 2VB6A 2GM1A 2Q2YA 2FL2A 2ZFKA 3DC4A 4PJJA 4LNUK 1FMWA 3ZCWA 4A51A 2GRYA 2X51A 3PXNA 1LKXA 2FL6A 1D0YA 1X88A 4B7BA 1D1CA 1SDMA 1V8KA 4PK4A 2ZFMA 1VFWA 2Y5WA 3T0QA 1BG2A 4PFPA 1MKJA 2VVGA 4ETPA 1MMDA 1MMNA 4E7ZA 2NCDA 3U06A 2UYMA 1FMVA 2X7EA 2X7CA 3X2TA 2Y65A 1BR1A 3CNZA 3GBJA 3NWNA 4GKRA 5LT3A 2ZFJA 3KINA 2Q2ZA 5GSZA 4A28A 1BR2A 4A1ZA 1LVKA 4AS7A 4DBRA 2O0AA 1BR4A 2FMEA 2WOGA 4ANJA 5LT4A 4A50A 1CZ7A 1MNEA 1V8JA 3WRDA 2KINA
chains in the Genus database with same CATH topology
3KARA 4PFOA 3L1CA 1D0ZA 2IEHA 1Q0BA 3ZFDA 5LT2A 1MMGA 1GOJA 1KK7A 4PJNA 2ZFIA 5HLEA 1D1BA 4AP0A 1F9WA 3DCBA 1VFVA 1F9TA 4Y05A 1VFZA 3K5EA 1MMAA 2UYIA 4BBGA 5LT1A 2ZFLA 3L9HA 1YRSA 3HQDA 1I6IA 4DBQA 3LREA 3COBA 1D1AA 1F9UA 4H1GA 4PJMA 2G1QA 2FKYA 3WPNA 2OWMA 4A14A 2PG2A 3ZFCA 1VOMA 4HNAK 1RY6A 2X7DA 1VFXA 3BFNA 3KENA 4BN2A 3B6VA 2XT3A 2V26A 2VASA 4ZHIA 3B6UA 1T5CA 3K3BA 4ZCAA 2MYSA 3CJOA 4E7SA 5LT0A 1G8XA 1I5SA 4UBFA 3H4SA 1N6MA 2XAEA 4FRZA 1D0XA 4A5YA 4PJLA 1II6A 1F9VA 4BXNA 2X2RA 2HEHA 2VB6A 2GM1A 2Q2YA 2FL2A 2ZFKA 3DC4A 4PJJA 4LNUK 1FMWA 3ZCWA 4A51A 2GRYA 2X51A 3PXNA 1LKXA 2FL6A 1D0YA 1X88A 4B7BA 1D1CA 1SDMA 1V8KA 4PK4A 2ZFMA 1VFWA 2Y5WA 3T0QA 1BG2A 4PFPA 1MKJA 2VVGA 4ETPA 1MMDA 1MMNA 4E7ZA 2NCDA 3U06A 2UYMA 1FMVA 2X7EA 2X7CA 3X2TA 2Y65A 1BR1A 3CNZA 3GBJA 3NWNA 4GKRA 5LT3A 2ZFJA 3KINA 2Q2ZA 5GSZA 4A28A 1BR2A 4A1ZA 1LVKA 4AS7A 4DBRA 1BR4A 2FMEA 2WOGA 4ANJA 5LT4A 4A50A 1CZ7A 1MNEA 1V8JA 3WRDA 2KINA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KAR A;  4PFO A;  3L1C A;  1D0Z A;  2IEH A;  1Q0B A;  3ZFD A;  5LT2 A;  1MMG A;  1GOJ A;  1KK7 A;  4PJN A;  2ZFI A;  5HLE A;  1D1B A;  4AP0 A;  1F9W A;  3DCB A;  1VFV A;  1F9T A;  4Y05 A;  1VFZ A;  3K5E A;  1MMA A;  2UYI A;  4BBG A;  5LT1 A;  2ZFL A;  3L9H A;  1YRS A;  3HQD A;  1I6I A;  4DBQ A;  3LRE A;  3COB A;  1D1A A;  1F9U A;  4H1G A;  4PJM A;  2G1Q A;  2FKY A;  3WPN A;  2OWM A;  4A14 A;  2PG2 A;  3ZFC A;  1VOM A;  4HNA K;  1RY6 A;  2X7D A;  1VFX A;  3BFN A;  3KEN A;  4BN2 A;  3B6V A;  2XT3 A;  2V26 A;  2VAS A;  4ZHI A;  3B6U A;  1T5C A;  3K3B A;  4ZCA A;  2MYS A;  3CJO A;  4E7S A;  5LT0 A;  1G8X A;  1I5S A;  4UBF A;  3H4S A;  1N6M A;  2XAE A;  4FRZ A;  1D0X A;  4A5Y A;  4PJL A;  1II6 A;  1F9V A;  4BXN A;  2X2R A;  2HEH A;  2VB6 A;  2GM1 A;  2Q2Y A;  2FL2 A;  2ZFK A;  3DC4 A;  4PJJ A;  4LNU K;  1FMW A;  3ZCW A;  4A51 A;  2GRY A;  2X51 A;  3PXN A;  1LKX A;  2FL6 A;  1D0Y A;  1X88 A;  4B7B A;  1D1C A;  1SDM A;  1V8K A;  4PK4 A;  2ZFM A;  1VFW A;  2Y5W A;  3T0Q A;  1BG2 A;  4PFP A;  1MKJ A;  2VVG A;  4ETP A;  1MMD A;  1MMN A;  4E7Z A;  2NCD A;  3U06 A;  2UYM A;  1FMV A;  2X7E A;  2X7C A;  3X2T A;  2Y65 A;  1BR1 A;  3CNZ A;  3GBJ A;  3NWN A;  4GKR A;  5LT3 A;  2ZFJ A;  3KIN A;  2Q2Z A;  5GSZ A;  4A28 A;  1BR2 A;  4A1Z A;  1LVK A;  4AS7 A;  4DBR A;  1BR4 A;  2FME A;  2WOG A;  4ANJ A;  5LT4 A;  4A50 A;  1CZ7 A;  1MNE A;  1V8J A;  3WRD A;  2KIN A; 
#chains in the Genus database with same CATH topology
 3KAR A;  4PFO A;  3L1C A;  1D0Z A;  2IEH A;  1Q0B A;  3ZFD A;  5LT2 A;  1MMG A;  1GOJ A;  1KK7 A;  4PJN A;  2ZFI A;  5HLE A;  1D1B A;  4AP0 A;  1F9W A;  3DCB A;  1VFV A;  1F9T A;  4Y05 A;  1VFZ A;  3K5E A;  1MMA A;  2UYI A;  4BBG A;  5LT1 A;  2ZFL A;  3L9H A;  1YRS A;  3HQD A;  1I6I A;  4GKP A;  4DBQ A;  3LRE A;  3COB A;  1D1A A;  1F9U A;  4H1G A;  4PJM A;  2G1Q A;  4GKQ A;  2FKY A;  3WPN A;  2OWM A;  4A14 A;  2PG2 A;  3ZFC A;  1VOM A;  4HNA K;  1RY6 A;  2X7D A;  1VFX A;  3BFN A;  3KEN A;  4BN2 A;  4ETP B;  3B6V A;  2XT3 A;  2V26 A;  2VAS A;  4ZHI A;  3B6U A;  1T5C A;  3K3B A;  4ZCA A;  2MYS A;  3CJO A;  4E7S A;  5LT0 A;  1G8X A;  1I5S A;  4UBF A;  3H4S A;  1N6M A;  2XAE A;  4FRZ A;  1D0X A;  4A5Y A;  4PJL A;  1II6 A;  1F9V A;  4BXN A;  2X2R A;  2HEH A;  2VB6 A;  2GM1 A;  2Q2Y A;  2FL2 A;  2ZFK A;  3DC4 A;  4PJJ A;  4LNU K;  1FMW A;  3ZCW A;  4A51 A;  2GRY A;  2X51 A;  3PXN A;  1LKX A;  2FL6 A;  1D0Y A;  1X88 A;  4B7B A;  1D1C A;  1SDM A;  1V8K A;  4PK4 A;  2ZFM A;  1VFW A;  2Y5W A;  3T0Q A;  1BG2 A;  4PFP A;  1MKJ A;  2VVG A;  4ETP A;  1MMD A;  1MMN A;  4E7Z A;  2NCD A;  3U06 A;  2UYM A;  1FMV A;  2X7E A;  2X7C A;  3X2T A;  2Y65 A;  1BR1 A;  3CNZ A;  3GBJ A;  3NWN A;  4GKR A;  5LT3 A;  2ZFJ A;  3KIN A;  2Q2Z A;  5GSZ A;  4A28 A;  1BR2 A;  4A1Z A;  1LVK A;  4AS7 A;  4DBR A;  2O0A A;  1BR4 A;  2FME A;  2WOG A;  4ANJ A;  5LT4 A;  4A50 A;  1CZ7 A;  1MNE A;  1V8J A;  3WRD A;  2KIN A; 
#chains in the Genus database with same CATH homology
 3KAR A;  4PFO A;  3L1C A;  1D0Z A;  2IEH A;  1Q0B A;  3ZFD A;  5LT2 A;  1MMG A;  1GOJ A;  1KK7 A;  4PJN A;  2ZFI A;  5HLE A;  1D1B A;  4AP0 A;  1F9W A;  3DCB A;  1VFV A;  1F9T A;  4Y05 A;  1VFZ A;  3K5E A;  1MMA A;  2UYI A;  4BBG A;  5LT1 A;  2ZFL A;  3L9H A;  1YRS A;  3HQD A;  1I6I A;  4DBQ A;  3LRE A;  3COB A;  1D1A A;  1F9U A;  4H1G A;  4PJM A;  2G1Q A;  2FKY A;  3WPN A;  2OWM A;  4A14 A;  2PG2 A;  3ZFC A;  1VOM A;  4HNA K;  1RY6 A;  2X7D A;  1VFX A;  3BFN A;  3KEN A;  4BN2 A;  3B6V A;  2XT3 A;  2V26 A;  2VAS A;  4ZHI A;  3B6U A;  1T5C A;  3K3B A;  4ZCA A;  2MYS A;  3CJO A;  4E7S A;  5LT0 A;  1G8X A;  1I5S A;  4UBF A;  3H4S A;  1N6M A;  2XAE A;  4FRZ A;  1D0X A;  4A5Y A;  4PJL A;  1II6 A;  1F9V A;  4BXN A;  2X2R A;  2HEH A;  2VB6 A;  2GM1 A;  2Q2Y A;  2FL2 A;  2ZFK A;  3DC4 A;  4PJJ A;  4LNU K;  1FMW A;  3ZCW A;  4A51 A;  2GRY A;  2X51 A;  3PXN A;  1LKX A;  2FL6 A;  1D0Y A;  1X88 A;  4B7B A;  1D1C A;  1SDM A;  1V8K A;  4PK4 A;  2ZFM A;  1VFW A;  2Y5W A;  3T0Q A;  1BG2 A;  4PFP A;  1MKJ A;  2VVG A;  4ETP A;  1MMD A;  1MMN A;  4E7Z A;  2NCD A;  3U06 A;  2UYM A;  1FMV A;  2X7E A;  2X7C A;  3X2T A;  2Y65 A;  1BR1 A;  3CNZ A;  3GBJ A;  3NWN A;  4GKR A;  5LT3 A;  2ZFJ A;  3KIN A;  2Q2Z A;  5GSZ A;  4A28 A;  1BR2 A;  4A1Z A;  1LVK A;  4AS7 A;  4DBR A;  1BR4 A;  2FME A;  2WOG A;  4ANJ A;  5LT4 A;  4A50 A;  1CZ7 A;  1MNE A;  1V8J A;  3WRD A;  2KIN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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