1T5CA

Crystal structure of the motor domain of human kinetochore protein cenp-e
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
336
structure length
322
Chain Sequence
b'EGAVAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTKNVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGSEDHLGVIPRAIHDIFQKIKKFPDREFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTSEMALKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGSVKVSHLNLVDLAGSERAARLKEGCNINRSLFILGQVIKKLSDGQVGGFINYRDSKLTRILQNSLGGNAKTRIICTITPVSFDETLTALQFASTAKYMKNTPYVNEVS'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Centromeric protein E
publication title Crystal structure of the motor domain of the human kinetochore protein CENP-E.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Contractile protein
total genus 97
structure length 322
sequence length 336
chains with identical sequence B
ec nomenclature
pdb deposition date 2004-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 1t5cA00
4A51A 2ZFKA 4A28A 1MMAA 3WRDA 1BR1A 1SDMA 2NCDA 3KINA 1V8JA 3H4SA 3ZCWA 4Y05A 4ETPA 3K3BA 2V26A 1F9VA 1G8XA 1BG2A 5LT2A 1LVKA 1N6MA 4AP0A 3PXNA 1BR4A 1FMVA 2VASA 4BBGA 4H1GA 3LREA 2Y65A 3WPNA 4PJJA 2WOGA 1MMGA 4A14A 1X88A 1KK7A 4B7BA 4A1ZA 5LT1A 1V8KA 2ZFLA 3T0QA 2PG2A 4PJNA 1D0XA 4ZCAA 3KENA 4LNUK 2ZFMA 3B6VA 3GBJA 3L9HA 4PFPA 4E7ZA 3CJOA 4PK4A 1D1AA 4A50A 2FL2A 4HNAK 1D1BA 4BXNA 2IEHA 3L1CA 2UYMA 5GSZA 2ZFJA 3K5EA 3NWNA 5HLEA 2Q2YA 2MYSA 5LT0A 1I5SA 1D0YA 3KARA 1MNEA 1D1CA 4BN2A 1VFZA 2X7DA 4ANJA 4AS7A 1GOJA 2X7EA 1VOMA 4PJLA 2X51A 1I6IA 4PFOA 4E7SA 2FKYA 1BR2A 4ZHIA 2XT3A 1D0ZA 1MKJA 4DBRA 2ZFIA 2G1QA 3X2TA 5LT4A 2VB6A 1II6A 1VFWA 1VFXA 1YRSA 4PJMA 3HQDA 1VFVA 2UYIA 1MMDA 2Q2ZA 3ZFCA 2XAEA 1Q0BA 1MMNA 1FMWA 3CNZA 2GRYA 4UBFA 2X2RA 4GKRA 3ZFDA 1F9WA 2KINA 3U06A 1RY6A 2GM1A 3DC4A 1T5CA 1F9UA 3DCBA 4A5YA 2VVGA 2Y5WA 3BFNA 4FRZA 5LT3A 3B6UA 1F9TA 3COBA 2OWMA 2FL6A 2X7CA 1LKXA 2HEHA 1CZ7A 2FMEA 4DBQA
chains in the Genus database with same CATH superfamily
4A51A 2ZFKA 4A28A 1MMAA 3WRDA 1BR1A 4GKPA 1SDMA 2NCDA 3KINA 1V8JA 3H4SA 3ZCWA 4Y05A 2O0AA 4ETPA 3K3BA 2V26A 1F9VA 1G8XA 1BG2A 5LT2A 1LVKA 1N6MA 4AP0A 3PXNA 1BR4A 1FMVA 2VASA 4BBGA 4H1GA 3LREA 2Y65A 3WPNA 4PJJA 2WOGA 1MMGA 4A14A 1X88A 1KK7A 4B7BA 4A1ZA 5LT1A 1V8KA 2ZFLA 3T0QA 2PG2A 4PJNA 1D0XA 4ZCAA 3KENA 4LNUK 2ZFMA 3B6VA 3GBJA 3L9HA 4PFPA 4E7ZA 3CJOA 4PK4A 1D1AA 4A50A 2FL2A 4HNAK 1D1BA 4BXNA 2IEHA 3L1CA 2UYMA 5GSZA 2ZFJA 3K5EA 3NWNA 5HLEA 2Q2YA 2MYSA 5LT0A 1I5SA 1D0YA 3KARA 1MNEA 1D1CA 4BN2A 1VFZA 2X7DA 4ANJA 4AS7A 1GOJA 2X7EA 1VOMA 4PJLA 2X51A 1I6IA 4PFOA 4E7SA 2FKYA 4GKQA 1BR2A 4ZHIA 2XT3A 1D0ZA 1MKJA 4DBRA 2ZFIA 2G1QA 4ETPB 3X2TA 5LT4A 2VB6A 1II6A 1VFWA 1VFXA 1YRSA 4PJMA 3HQDA 1VFVA 2UYIA 1MMDA 2Q2ZA 3ZFCA 2XAEA 1Q0BA 1MMNA 1FMWA 3CNZA 2GRYA 4UBFA 2X2RA 4GKRA 3ZFDA 1F9WA 2KINA 3U06A 1RY6A 2GM1A 3DC4A 1T5CA 1F9UA 3DCBA 4A5YA 2VVGA 2Y5WA 3BFNA 4FRZA 5LT3A 3B6UA 1F9TA 3COBA 2OWMA 2FL6A 2X7CA 1LKXA 2HEHA 1CZ7A 2FMEA 4DBQA
chains in the Genus database with same CATH topology
4A51A 2ZFKA 4A28A 1MMAA 3WRDA 1BR1A 1SDMA 2NCDA 3KINA 1V8JA 3H4SA 3ZCWA 4Y05A 4ETPA 3K3BA 2V26A 1F9VA 1G8XA 1BG2A 5LT2A 1LVKA 1N6MA 4AP0A 3PXNA 1BR4A 1FMVA 2VASA 4BBGA 4H1GA 3LREA 2Y65A 3WPNA 4PJJA 2WOGA 1MMGA 4A14A 1X88A 1KK7A 4B7BA 4A1ZA 5LT1A 1V8KA 2ZFLA 3T0QA 2PG2A 4PJNA 1D0XA 4ZCAA 3KENA 4LNUK 2ZFMA 3B6VA 3GBJA 3L9HA 4PFPA 4E7ZA 3CJOA 4PK4A 1D1AA 4A50A 2FL2A 4HNAK 1D1BA 4BXNA 2IEHA 3L1CA 2UYMA 5GSZA 2ZFJA 3K5EA 3NWNA 5HLEA 2Q2YA 2MYSA 5LT0A 1I5SA 1D0YA 3KARA 1MNEA 1D1CA 4BN2A 1VFZA 2X7DA 4ANJA 4AS7A 1GOJA 2X7EA 1VOMA 4PJLA 2X51A 1I6IA 4PFOA 4E7SA 2FKYA 1BR2A 4ZHIA 2XT3A 1D0ZA 1MKJA 4DBRA 2ZFIA 2G1QA 3X2TA 5LT4A 2VB6A 1II6A 1VFWA 1VFXA 1YRSA 4PJMA 3HQDA 1VFVA 2UYIA 1MMDA 2Q2ZA 3ZFCA 2XAEA 1Q0BA 1MMNA 1FMWA 3CNZA 2GRYA 4UBFA 2X2RA 4GKRA 3ZFDA 1F9WA 2KINA 3U06A 1RY6A 2GM1A 3DC4A 1T5CA 1F9UA 3DCBA 4A5YA 2VVGA 2Y5WA 3BFNA 4FRZA 5LT3A 3B6UA 1F9TA 3COBA 2OWMA 2FL6A 2X7CA 1LKXA 2HEHA 1CZ7A 2FMEA 4DBQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A51 A;  2ZFK A;  4A28 A;  1MMA A;  3WRD A;  1BR1 A;  1SDM A;  2NCD A;  3KIN A;  1V8J A;  3H4S A;  3ZCW A;  4Y05 A;  4ETP A;  3K3B A;  2V26 A;  1F9V A;  1G8X A;  1BG2 A;  5LT2 A;  1LVK A;  1N6M A;  4AP0 A;  3PXN A;  1BR4 A;  1FMV A;  2VAS A;  4BBG A;  4H1G A;  3LRE A;  2Y65 A;  3WPN A;  4PJJ A;  2WOG A;  1MMG A;  4A14 A;  1X88 A;  1KK7 A;  4B7B A;  4A1Z A;  5LT1 A;  1V8K A;  2ZFL A;  3T0Q A;  2PG2 A;  4PJN A;  1D0X A;  4ZCA A;  3KEN A;  4LNU K;  2ZFM A;  3B6V A;  3GBJ A;  3L9H A;  4PFP A;  4E7Z A;  3CJO A;  4PK4 A;  1D1A A;  4A50 A;  2FL2 A;  4HNA K;  1D1B A;  4BXN A;  2IEH A;  3L1C A;  2UYM A;  5GSZ A;  2ZFJ A;  3K5E A;  3NWN A;  5HLE A;  2Q2Y A;  2MYS A;  5LT0 A;  1I5S A;  1D0Y A;  3KAR A;  1MNE A;  1D1C A;  4BN2 A;  1VFZ A;  2X7D A;  4ANJ A;  4AS7 A;  1GOJ A;  2X7E A;  1VOM A;  4PJL A;  2X51 A;  1I6I A;  4PFO A;  4E7S A;  2FKY A;  1BR2 A;  4ZHI A;  2XT3 A;  1D0Z A;  1MKJ A;  4DBR A;  2ZFI A;  2G1Q A;  3X2T A;  5LT4 A;  2VB6 A;  1II6 A;  1VFW A;  1VFX A;  1YRS A;  4PJM A;  3HQD A;  1VFV A;  2UYI A;  1MMD A;  2Q2Z A;  3ZFC A;  2XAE A;  1Q0B A;  1MMN A;  1FMW A;  3CNZ A;  2GRY A;  4UBF A;  2X2R A;  4GKR A;  3ZFD A;  1F9W A;  2KIN A;  3U06 A;  1RY6 A;  2GM1 A;  3DC4 A;  1T5C A;  1F9U A;  3DCB A;  4A5Y A;  2VVG A;  2Y5W A;  3BFN A;  4FRZ A;  5LT3 A;  3B6U A;  1F9T A;  3COB A;  2OWM A;  2FL6 A;  2X7C A;  1LKX A;  2HEH A;  1CZ7 A;  2FME A;  4DBQ A; 
#chains in the Genus database with same CATH topology
 4A51 A;  2ZFK A;  4A28 A;  1MMA A;  3WRD A;  1BR1 A;  4GKP A;  1SDM A;  2NCD A;  3KIN A;  1V8J A;  3H4S A;  3ZCW A;  4Y05 A;  2O0A A;  4ETP A;  3K3B A;  2V26 A;  1F9V A;  1G8X A;  1BG2 A;  5LT2 A;  1LVK A;  1N6M A;  4AP0 A;  3PXN A;  1BR4 A;  1FMV A;  2VAS A;  4BBG A;  4H1G A;  3LRE A;  2Y65 A;  3WPN A;  4PJJ A;  2WOG A;  1MMG A;  4A14 A;  1X88 A;  1KK7 A;  4B7B A;  4A1Z A;  5LT1 A;  1V8K A;  2ZFL A;  3T0Q A;  2PG2 A;  4PJN A;  1D0X A;  4ZCA A;  3KEN A;  4LNU K;  2ZFM A;  3B6V A;  3GBJ A;  3L9H A;  4PFP A;  4E7Z A;  3CJO A;  4PK4 A;  1D1A A;  4A50 A;  2FL2 A;  4HNA K;  1D1B A;  4BXN A;  2IEH A;  3L1C A;  2UYM A;  5GSZ A;  2ZFJ A;  3K5E A;  3NWN A;  5HLE A;  2Q2Y A;  2MYS A;  5LT0 A;  1I5S A;  1D0Y A;  3KAR A;  1MNE A;  1D1C A;  4BN2 A;  1VFZ A;  2X7D A;  4ANJ A;  4AS7 A;  1GOJ A;  2X7E A;  1VOM A;  4PJL A;  2X51 A;  1I6I A;  4PFO A;  4E7S A;  2FKY A;  4GKQ A;  1BR2 A;  4ZHI A;  2XT3 A;  1D0Z A;  1MKJ A;  4DBR A;  2ZFI A;  2G1Q A;  4ETP B;  3X2T A;  5LT4 A;  2VB6 A;  1II6 A;  1VFW A;  1VFX A;  1YRS A;  4PJM A;  3HQD A;  1VFV A;  2UYI A;  1MMD A;  2Q2Z A;  3ZFC A;  2XAE A;  1Q0B A;  1MMN A;  1FMW A;  3CNZ A;  2GRY A;  4UBF A;  2X2R A;  4GKR A;  3ZFD A;  1F9W A;  2KIN A;  3U06 A;  1RY6 A;  2GM1 A;  3DC4 A;  1T5C A;  1F9U A;  3DCB A;  4A5Y A;  2VVG A;  2Y5W A;  3BFN A;  4FRZ A;  5LT3 A;  3B6U A;  1F9T A;  3COB A;  2OWM A;  2FL6 A;  2X7C A;  1LKX A;  2HEH A;  1CZ7 A;  2FME A;  4DBQ A; 
#chains in the Genus database with same CATH homology
 4A51 A;  2ZFK A;  4A28 A;  1MMA A;  3WRD A;  1BR1 A;  1SDM A;  2NCD A;  3KIN A;  1V8J A;  3H4S A;  3ZCW A;  4Y05 A;  4ETP A;  3K3B A;  2V26 A;  1F9V A;  1G8X A;  1BG2 A;  5LT2 A;  1LVK A;  1N6M A;  4AP0 A;  3PXN A;  1BR4 A;  1FMV A;  2VAS A;  4BBG A;  4H1G A;  3LRE A;  2Y65 A;  3WPN A;  4PJJ A;  2WOG A;  1MMG A;  4A14 A;  1X88 A;  1KK7 A;  4B7B A;  4A1Z A;  5LT1 A;  1V8K A;  2ZFL A;  3T0Q A;  2PG2 A;  4PJN A;  1D0X A;  4ZCA A;  3KEN A;  4LNU K;  2ZFM A;  3B6V A;  3GBJ A;  3L9H A;  4PFP A;  4E7Z A;  3CJO A;  4PK4 A;  1D1A A;  4A50 A;  2FL2 A;  4HNA K;  1D1B A;  4BXN A;  2IEH A;  3L1C A;  2UYM A;  5GSZ A;  2ZFJ A;  3K5E A;  3NWN A;  5HLE A;  2Q2Y A;  2MYS A;  5LT0 A;  1I5S A;  1D0Y A;  3KAR A;  1MNE A;  1D1C A;  4BN2 A;  1VFZ A;  2X7D A;  4ANJ A;  4AS7 A;  1GOJ A;  2X7E A;  1VOM A;  4PJL A;  2X51 A;  1I6I A;  4PFO A;  4E7S A;  2FKY A;  1BR2 A;  4ZHI A;  2XT3 A;  1D0Z A;  1MKJ A;  4DBR A;  2ZFI A;  2G1Q A;  3X2T A;  5LT4 A;  2VB6 A;  1II6 A;  1VFW A;  1VFX A;  1YRS A;  4PJM A;  3HQD A;  1VFV A;  2UYI A;  1MMD A;  2Q2Z A;  3ZFC A;  2XAE A;  1Q0B A;  1MMN A;  1FMW A;  3CNZ A;  2GRY A;  4UBF A;  2X2R A;  4GKR A;  3ZFD A;  1F9W A;  2KIN A;  3U06 A;  1RY6 A;  2GM1 A;  3DC4 A;  1T5C A;  1F9U A;  3DCB A;  4A5Y A;  2VVG A;  2Y5W A;  3BFN A;  4FRZ A;  5LT3 A;  3B6U A;  1F9T A;  3COB A;  2OWM A;  2FL6 A;  2X7C A;  1LKX A;  2HEH A;  1CZ7 A;  2FME A;  4DBQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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