5LT3A

Nucleotide-free kinesin-1 motor domain t87a mutant, p1 crystal form
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
319
structure length
307
Chain Sequence
ESNIKVMCRFRPLNSEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDAAKKIVKDVLEGYNGTIFAYGQASSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGATERFVSSPDEVMDTIDEGKSNRHVAVHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNARTTIVICCSPSSYNESETKSTLLFGQRAKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structural switch of nucleotide-free kinesin.
pubmed doi rcsb
molecule tags Motor protein
source organism Homo sapiens
molecule keywords Kinesin-1 heavy chain
total genus 99
structure length 307
sequence length 319
chains with identical sequence B, C, D, E, K
ec nomenclature
pdb deposition date 2016-09-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 5lt3A00
2VB6A 3ZFDA 1MKJA 2VVGA 1F9WA 1FMWA 1X88A 4B7BA 3B6UA 2FL2A 2ZFJA 3L9HA 2GM1A 1D1AA 3KARA 5LT4A 4PFOA 2XAEA 2NCDA 5HLEA 2FKYA 2ZFIA 3WPNA 3ZCWA 1LVKA 2MYSA 1MMAA 1GOJA 1MMGA 2FL6A 1BR2A 1MMNA 1V8KA 2X7CA 5GSZA 4BBGA 1BG2A 1YRSA 4Y05A 1Q0BA 4LNUK 5LT1A 4A5YA 3X2TA 3T0QA 2XT3A 1N6MA 2ZFMA 4FRZA 3PXNA 4UBFA 4E7SA 4ZHIA 4HNAK 1BR1A 2Y5WA 2OWMA 4ETPA 2Q2ZA 3CJOA 4H1GA 1VFVA 1D1CA 1VFWA 1KK7A 4PK4A 1D0ZA 1VFXA 1SDMA 5LT0A 2UYIA 1F9UA 4A51A 2GRYA 5LT3A 1I6IA 3HQDA 4A28A 4GKRA 3BFNA 1MNEA 4A14A 4DBRA 3B6VA 1VOMA 3KENA 4A50A 3KINA 4PJJA 4PFPA 1D0YA 1FMVA 3CNZA 3GBJA 3U06A 1F9VA 1I5SA 3K5EA 1VFZA 1D1BA 2KINA 2Y65A 1LKXA 2G1QA 2X51A 1D0XA 1II6A 4A1ZA 3DC4A 4ZCAA 3ZFCA 2ZFKA 2Q2YA 1T5CA 1G8XA 4DBQA 1F9TA 3WRDA 4PJLA 2UYMA 2X2RA 2VASA 4E7ZA 4PJNA 2X7EA 3H4SA 1CZ7A 2PG2A 2ZFLA 4AP0A 4PJMA 3LREA 1BR4A 5LT2A 4AS7A 1MMDA 1V8JA 2HEHA 3COBA 3DCBA 3NWNA 1RY6A 4BN2A 2FMEA 2X7DA 4ANJA 3K3BA 2WOGA 4BXNA 2V26A 2IEHA 3L1CA
chains in the Genus database with same CATH superfamily
2VB6A 2O0AA 3ZFDA 1MKJA 2VVGA 1F9WA 1FMWA 1X88A 4B7BA 3B6UA 2FL2A 2ZFJA 3L9HA 2GM1A 1D1AA 4GKPA 3KARA 5LT4A 4PFOA 2XAEA 2NCDA 5HLEA 2FKYA 2ZFIA 3WPNA 3ZCWA 1LVKA 2MYSA 1MMAA 1GOJA 1MMGA 2FL6A 1BR2A 1MMNA 1V8KA 2X7CA 5GSZA 4BBGA 1BG2A 1YRSA 4Y05A 1Q0BA 4LNUK 5LT1A 4A5YA 3X2TA 3T0QA 2XT3A 1N6MA 2ZFMA 4FRZA 3PXNA 4UBFA 4E7SA 4ZHIA 4HNAK 1BR1A 2Y5WA 2OWMA 4ETPA 2Q2ZA 3CJOA 4H1GA 1VFVA 1D1CA 1VFWA 1KK7A 4PK4A 1D0ZA 1VFXA 4GKQA 1SDMA 5LT0A 2UYIA 1F9UA 4A51A 4ETPB 2GRYA 5LT3A 1I6IA 3HQDA 4A28A 4GKRA 3BFNA 1MNEA 4A14A 4DBRA 3B6VA 1VOMA 3KENA 4A50A 3KINA 4PJJA 4PFPA 1D0YA 1FMVA 3CNZA 3GBJA 3U06A 1F9VA 1I5SA 3K5EA 1VFZA 1D1BA 2KINA 2Y65A 1LKXA 2G1QA 2X51A 1D0XA 1II6A 4A1ZA 3DC4A 4ZCAA 3ZFCA 2ZFKA 2Q2YA 1T5CA 1G8XA 4DBQA 1F9TA 3WRDA 4PJLA 2UYMA 2X2RA 2VASA 4E7ZA 4PJNA 2X7EA 3H4SA 1CZ7A 2PG2A 2ZFLA 4AP0A 4PJMA 3LREA 1BR4A 5LT2A 4AS7A 1MMDA 1V8JA 2HEHA 3COBA 3DCBA 3NWNA 1RY6A 4BN2A 2FMEA 2X7DA 4ANJA 3K3BA 2WOGA 4BXNA 2V26A 2IEHA 3L1CA
chains in the Genus database with same CATH topology
2VB6A 3ZFDA 1MKJA 2VVGA 1F9WA 1FMWA 1X88A 4B7BA 3B6UA 2FL2A 2ZFJA 3L9HA 2GM1A 1D1AA 3KARA 5LT4A 4PFOA 2XAEA 2NCDA 5HLEA 2FKYA 2ZFIA 3WPNA 3ZCWA 1LVKA 2MYSA 1MMAA 1GOJA 1MMGA 2FL6A 1BR2A 1MMNA 1V8KA 2X7CA 5GSZA 4BBGA 1BG2A 1YRSA 4Y05A 1Q0BA 4LNUK 5LT1A 4A5YA 3X2TA 3T0QA 2XT3A 1N6MA 2ZFMA 4FRZA 3PXNA 4UBFA 4E7SA 4ZHIA 4HNAK 1BR1A 2Y5WA 2OWMA 4ETPA 2Q2ZA 3CJOA 4H1GA 1VFVA 1D1CA 1VFWA 1KK7A 4PK4A 1D0ZA 1VFXA 1SDMA 5LT0A 2UYIA 1F9UA 4A51A 2GRYA 5LT3A 1I6IA 3HQDA 4A28A 4GKRA 3BFNA 1MNEA 4A14A 4DBRA 3B6VA 1VOMA 3KENA 4A50A 3KINA 4PJJA 4PFPA 1D0YA 1FMVA 3CNZA 3GBJA 3U06A 1F9VA 1I5SA 3K5EA 1VFZA 1D1BA 2KINA 2Y65A 1LKXA 2G1QA 2X51A 1D0XA 1II6A 4A1ZA 3DC4A 4ZCAA 3ZFCA 2ZFKA 2Q2YA 1T5CA 1G8XA 4DBQA 1F9TA 3WRDA 4PJLA 2UYMA 2X2RA 2VASA 4E7ZA 4PJNA 2X7EA 3H4SA 1CZ7A 2PG2A 2ZFLA 4AP0A 4PJMA 3LREA 1BR4A 5LT2A 4AS7A 1MMDA 1V8JA 2HEHA 3COBA 3DCBA 3NWNA 1RY6A 4BN2A 2FMEA 2X7DA 4ANJA 3K3BA 2WOGA 4BXNA 2V26A 2IEHA 3L1CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VB6 A;  3ZFD A;  1MKJ A;  2VVG A;  1F9W A;  1FMW A;  1X88 A;  4B7B A;  3B6U A;  2FL2 A;  2ZFJ A;  3L9H A;  2GM1 A;  1D1A A;  3KAR A;  5LT4 A;  4PFO A;  2XAE A;  2NCD A;  5HLE A;  2FKY A;  2ZFI A;  3WPN A;  3ZCW A;  1LVK A;  2MYS A;  1MMA A;  1GOJ A;  1MMG A;  2FL6 A;  1BR2 A;  1MMN A;  1V8K A;  2X7C A;  5GSZ A;  4BBG A;  1BG2 A;  1YRS A;  4Y05 A;  1Q0B A;  4LNU K;  5LT1 A;  4A5Y A;  3X2T A;  3T0Q A;  2XT3 A;  1N6M A;  2ZFM A;  4FRZ A;  3PXN A;  4UBF A;  4E7S A;  4ZHI A;  4HNA K;  1BR1 A;  2Y5W A;  2OWM A;  4ETP A;  2Q2Z A;  3CJO A;  4H1G A;  1VFV A;  1D1C A;  1VFW A;  1KK7 A;  4PK4 A;  1D0Z A;  1VFX A;  1SDM A;  5LT0 A;  2UYI A;  1F9U A;  4A51 A;  2GRY A;  5LT3 A;  1I6I A;  3HQD A;  4A28 A;  4GKR A;  3BFN A;  1MNE A;  4A14 A;  4DBR A;  3B6V A;  1VOM A;  3KEN A;  4A50 A;  3KIN A;  4PJJ A;  4PFP A;  1D0Y A;  1FMV A;  3CNZ A;  3GBJ A;  3U06 A;  1F9V A;  1I5S A;  3K5E A;  1VFZ A;  1D1B A;  2KIN A;  2Y65 A;  1LKX A;  2G1Q A;  2X51 A;  1D0X A;  1II6 A;  4A1Z A;  3DC4 A;  4ZCA A;  3ZFC A;  2ZFK A;  2Q2Y A;  1T5C A;  1G8X A;  4DBQ A;  1F9T A;  3WRD A;  4PJL A;  2UYM A;  2X2R A;  2VAS A;  4E7Z A;  4PJN A;  2X7E A;  3H4S A;  1CZ7 A;  2PG2 A;  2ZFL A;  4AP0 A;  4PJM A;  3LRE A;  1BR4 A;  5LT2 A;  4AS7 A;  1MMD A;  1V8J A;  2HEH A;  3COB A;  3DCB A;  3NWN A;  1RY6 A;  4BN2 A;  2FME A;  2X7D A;  4ANJ A;  3K3B A;  2WOG A;  4BXN A;  2V26 A;  2IEH A;  3L1C A; 
#chains in the Genus database with same CATH topology
 2VB6 A;  2O0A A;  3ZFD A;  1MKJ A;  2VVG A;  1F9W A;  1FMW A;  1X88 A;  4B7B A;  3B6U A;  2FL2 A;  2ZFJ A;  3L9H A;  2GM1 A;  1D1A A;  4GKP A;  3KAR A;  5LT4 A;  4PFO A;  2XAE A;  2NCD A;  5HLE A;  2FKY A;  2ZFI A;  3WPN A;  3ZCW A;  1LVK A;  2MYS A;  1MMA A;  1GOJ A;  1MMG A;  2FL6 A;  1BR2 A;  1MMN A;  1V8K A;  2X7C A;  5GSZ A;  4BBG A;  1BG2 A;  1YRS A;  4Y05 A;  1Q0B A;  4LNU K;  5LT1 A;  4A5Y A;  3X2T A;  3T0Q A;  2XT3 A;  1N6M A;  2ZFM A;  4FRZ A;  3PXN A;  4UBF A;  4E7S A;  4ZHI A;  4HNA K;  1BR1 A;  2Y5W A;  2OWM A;  4ETP A;  2Q2Z A;  3CJO A;  4H1G A;  1VFV A;  1D1C A;  1VFW A;  1KK7 A;  4PK4 A;  1D0Z A;  1VFX A;  4GKQ A;  1SDM A;  5LT0 A;  2UYI A;  1F9U A;  4A51 A;  4ETP B;  2GRY A;  5LT3 A;  1I6I A;  3HQD A;  4A28 A;  4GKR A;  3BFN A;  1MNE A;  4A14 A;  4DBR A;  3B6V A;  1VOM A;  3KEN A;  4A50 A;  3KIN A;  4PJJ A;  4PFP A;  1D0Y A;  1FMV A;  3CNZ A;  3GBJ A;  3U06 A;  1F9V A;  1I5S A;  3K5E A;  1VFZ A;  1D1B A;  2KIN A;  2Y65 A;  1LKX A;  2G1Q A;  2X51 A;  1D0X A;  1II6 A;  4A1Z A;  3DC4 A;  4ZCA A;  3ZFC A;  2ZFK A;  2Q2Y A;  1T5C A;  1G8X A;  4DBQ A;  1F9T A;  3WRD A;  4PJL A;  2UYM A;  2X2R A;  2VAS A;  4E7Z A;  4PJN A;  2X7E A;  3H4S A;  1CZ7 A;  2PG2 A;  2ZFL A;  4AP0 A;  4PJM A;  3LRE A;  1BR4 A;  5LT2 A;  4AS7 A;  1MMD A;  1V8J A;  2HEH A;  3COB A;  3DCB A;  3NWN A;  1RY6 A;  4BN2 A;  2FME A;  2X7D A;  4ANJ A;  3K3B A;  2WOG A;  4BXN A;  2V26 A;  2IEH A;  3L1C A; 
#chains in the Genus database with same CATH homology
 2VB6 A;  3ZFD A;  1MKJ A;  2VVG A;  1F9W A;  1FMW A;  1X88 A;  4B7B A;  3B6U A;  2FL2 A;  2ZFJ A;  3L9H A;  2GM1 A;  1D1A A;  3KAR A;  5LT4 A;  4PFO A;  2XAE A;  2NCD A;  5HLE A;  2FKY A;  2ZFI A;  3WPN A;  3ZCW A;  1LVK A;  2MYS A;  1MMA A;  1GOJ A;  1MMG A;  2FL6 A;  1BR2 A;  1MMN A;  1V8K A;  2X7C A;  5GSZ A;  4BBG A;  1BG2 A;  1YRS A;  4Y05 A;  1Q0B A;  4LNU K;  5LT1 A;  4A5Y A;  3X2T A;  3T0Q A;  2XT3 A;  1N6M A;  2ZFM A;  4FRZ A;  3PXN A;  4UBF A;  4E7S A;  4ZHI A;  4HNA K;  1BR1 A;  2Y5W A;  2OWM A;  4ETP A;  2Q2Z A;  3CJO A;  4H1G A;  1VFV A;  1D1C A;  1VFW A;  1KK7 A;  4PK4 A;  1D0Z A;  1VFX A;  1SDM A;  5LT0 A;  2UYI A;  1F9U A;  4A51 A;  2GRY A;  5LT3 A;  1I6I A;  3HQD A;  4A28 A;  4GKR A;  3BFN A;  1MNE A;  4A14 A;  4DBR A;  3B6V A;  1VOM A;  3KEN A;  4A50 A;  3KIN A;  4PJJ A;  4PFP A;  1D0Y A;  1FMV A;  3CNZ A;  3GBJ A;  3U06 A;  1F9V A;  1I5S A;  3K5E A;  1VFZ A;  1D1B A;  2KIN A;  2Y65 A;  1LKX A;  2G1Q A;  2X51 A;  1D0X A;  1II6 A;  4A1Z A;  3DC4 A;  4ZCA A;  3ZFC A;  2ZFK A;  2Q2Y A;  1T5C A;  1G8X A;  4DBQ A;  1F9T A;  3WRD A;  4PJL A;  2UYM A;  2X2R A;  2VAS A;  4E7Z A;  4PJN A;  2X7E A;  3H4S A;  1CZ7 A;  2PG2 A;  2ZFL A;  4AP0 A;  4PJM A;  3LRE A;  1BR4 A;  5LT2 A;  4AS7 A;  1MMD A;  1V8J A;  2HEH A;  3COB A;  3DCB A;  3NWN A;  1RY6 A;  4BN2 A;  2FME A;  2X7D A;  4ANJ A;  3K3B A;  2WOG A;  4BXN A;  2V26 A;  2IEH A;  3L1C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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