5LT3A

Nucleotide-free kinesin-1 motor domain t87a mutant, p1 crystal form
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
319
structure length
307
Chain Sequence
ESNIKVMCRFRPLNSEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDAAKKIVKDVLEGYNGTIFAYGQASSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGATERFVSSPDEVMDTIDEGKSNRHVAVHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNARTTIVICCSPSSYNESETKSTLLFGQRAKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Kinesin-1 heavy chain
publication title The structural switch of nucleotide-free kinesin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Motor protein
total genus 99
structure length 307
sequence length 319
chains with identical sequence B, C, D, E, K
ec nomenclature
pdb deposition date 2016-09-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 5lt3A00
2FKYA 2X2RA 1VOMA 1VFXA 1V8KA 1BR1A 3DC4A 4A5YA 3PXNA 3L9HA 3BFNA 2X51A 5HLEA 1N6MA 4E7ZA 2WOGA 3K5EA 2ZFIA 3KINA 1II6A 4PJLA 1MMAA 4A1ZA 3U06A 4PFPA 1MKJA 1F9WA 5LT4A 2X7EA 4ANJA 1YRSA 1D0YA 1V8JA 2FL6A 4B7BA 1MMGA 4GKRA 2XT3A 4BBGA 4BXNA 1MNEA 2VASA 4ZCAA 4UBFA 2UYMA 3COBA 1FMVA 3WRDA 1F9VA 1D1AA 1MMNA 2V26A 2GM1A 2Q2YA 2ZFKA 3CJOA 1KK7A 5LT2A 2PG2A 4ZHIA 3H4SA 1I5SA 3DCBA 2UYIA 2OWMA 3NWNA 4PK4A 2MYSA 1FMWA 2FL2A 3ZFDA 3T0QA 3X2TA 2HEHA 5LT0A 4A51A 1VFVA 3HQDA 1T5CA 2KINA 1D1CA 1LVKA 4BN2A 3K3BA 1BR4A 1VFZA 1BR2A 4PFOA 1LKXA 4A28A 3L1CA 4PJNA 3ZFCA 2G1QA 2FMEA 1F9UA 2NCDA 1D0XA 2ZFJA 2ZFLA 4LNUK 4Y05A 2ZFMA 3B6VA 4E7SA 4FRZA 1SDMA 1Q0BA 1F9TA 4H1GA 2GRYA 4PJMA 4AP0A 1VFWA 1G8XA 2VVGA 4PJJA 4ETPA 3ZCWA 2X7CA 4A50A 1I6IA 2X7DA 2Y5WA 3LREA 1CZ7A 1X88A 3B6UA 2Q2ZA 3GBJA 3KARA 1D1BA 5LT3A 4DBRA 3KENA 4DBQA 5LT1A 2IEHA 1GOJA 1RY6A 2VB6A 2XAEA 5GSZA 3WPNA 1D0ZA 2Y65A 1BG2A 4HNAK 1MMDA 3CNZA 4A14A 4AS7A
chains in the Genus database with same CATH superfamily
2FKYA 2X2RA 1VOMA 1VFXA 1V8KA 1BR1A 3DC4A 4A5YA 3PXNA 3L9HA 3BFNA 2X51A 5HLEA 1N6MA 4E7ZA 2WOGA 3K5EA 2ZFIA 3KINA 1II6A 4PJLA 1MMAA 4A1ZA 3U06A 4PFPA 1MKJA 1F9WA 5LT4A 2X7EA 4ANJA 1YRSA 1D0YA 1V8JA 2FL6A 4B7BA 1MMGA 4GKRA 2XT3A 4BBGA 4BXNA 1MNEA 2VASA 4GKQA 4ZCAA 4UBFA 2UYMA 3COBA 1FMVA 3WRDA 1F9VA 1D1AA 1MMNA 2V26A 2GM1A 2Q2YA 2ZFKA 3CJOA 1KK7A 5LT2A 2PG2A 4ZHIA 3H4SA 1I5SA 3DCBA 2UYIA 2OWMA 3NWNA 4PK4A 2MYSA 1FMWA 2FL2A 3ZFDA 3T0QA 3X2TA 2HEHA 5LT0A 4A51A 1VFVA 4ETPB 3HQDA 1T5CA 2KINA 1D1CA 1LVKA 4BN2A 3K3BA 1BR4A 1VFZA 1BR2A 4PFOA 1LKXA 4A28A 3L1CA 4PJNA 3ZFCA 2G1QA 2FMEA 1F9UA 2NCDA 1D0XA 2ZFJA 2ZFLA 4LNUK 4Y05A 2ZFMA 3B6VA 4E7SA 4FRZA 1SDMA 1Q0BA 1F9TA 4H1GA 2GRYA 4PJMA 4AP0A 1VFWA 1G8XA 2VVGA 4PJJA 4ETPA 3ZCWA 2X7CA 4A50A 1I6IA 2X7DA 2Y5WA 3LREA 1CZ7A 1X88A 3B6UA 2Q2ZA 3GBJA 3KARA 1D1BA 5LT3A 4DBRA 3KENA 4DBQA 5LT1A 2IEHA 1GOJA 1RY6A 2VB6A 2XAEA 5GSZA 3WPNA 1D0ZA 2Y65A 2O0AA 4GKPA 1BG2A 4HNAK 1MMDA 3CNZA 4A14A 4AS7A
chains in the Genus database with same CATH topology
2FKYA 2X2RA 1VOMA 1VFXA 1V8KA 1BR1A 3DC4A 4A5YA 3PXNA 3L9HA 3BFNA 2X51A 5HLEA 1N6MA 4E7ZA 2WOGA 3K5EA 2ZFIA 3KINA 1II6A 4PJLA 1MMAA 4A1ZA 3U06A 4PFPA 1MKJA 1F9WA 5LT4A 2X7EA 4ANJA 1YRSA 1D0YA 1V8JA 2FL6A 4B7BA 1MMGA 4GKRA 2XT3A 4BBGA 4BXNA 1MNEA 2VASA 4ZCAA 4UBFA 2UYMA 3COBA 1FMVA 3WRDA 1F9VA 1D1AA 1MMNA 2V26A 2GM1A 2Q2YA 2ZFKA 3CJOA 1KK7A 5LT2A 2PG2A 4ZHIA 3H4SA 1I5SA 3DCBA 2UYIA 2OWMA 3NWNA 4PK4A 2MYSA 1FMWA 2FL2A 3ZFDA 3T0QA 3X2TA 2HEHA 5LT0A 4A51A 1VFVA 3HQDA 1T5CA 2KINA 1D1CA 1LVKA 4BN2A 3K3BA 1BR4A 1VFZA 1BR2A 4PFOA 1LKXA 4A28A 3L1CA 4PJNA 3ZFCA 2G1QA 2FMEA 1F9UA 2NCDA 1D0XA 2ZFJA 2ZFLA 4LNUK 4Y05A 2ZFMA 3B6VA 4E7SA 4FRZA 1SDMA 1Q0BA 1F9TA 4H1GA 2GRYA 4PJMA 4AP0A 1VFWA 1G8XA 2VVGA 4PJJA 4ETPA 3ZCWA 2X7CA 4A50A 1I6IA 2X7DA 2Y5WA 3LREA 1CZ7A 1X88A 3B6UA 2Q2ZA 3GBJA 3KARA 1D1BA 5LT3A 4DBRA 3KENA 4DBQA 5LT1A 2IEHA 1GOJA 1RY6A 2VB6A 2XAEA 5GSZA 3WPNA 1D0ZA 2Y65A 1BG2A 4HNAK 1MMDA 3CNZA 4A14A 4AS7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FKY A;  2X2R A;  1VOM A;  1VFX A;  1V8K A;  1BR1 A;  3DC4 A;  4A5Y A;  3PXN A;  3L9H A;  3BFN A;  2X51 A;  5HLE A;  1N6M A;  4E7Z A;  2WOG A;  3K5E A;  2ZFI A;  3KIN A;  1II6 A;  4PJL A;  1MMA A;  4A1Z A;  3U06 A;  4PFP A;  1MKJ A;  1F9W A;  5LT4 A;  2X7E A;  4ANJ A;  1YRS A;  1D0Y A;  1V8J A;  2FL6 A;  4B7B A;  1MMG A;  4GKR A;  2XT3 A;  4BBG A;  4BXN A;  1MNE A;  2VAS A;  4ZCA A;  4UBF A;  2UYM A;  3COB A;  1FMV A;  3WRD A;  1F9V A;  1D1A A;  1MMN A;  2V26 A;  2GM1 A;  2Q2Y A;  2ZFK A;  3CJO A;  1KK7 A;  5LT2 A;  2PG2 A;  4ZHI A;  3H4S A;  1I5S A;  3DCB A;  2UYI A;  2OWM A;  3NWN A;  4PK4 A;  2MYS A;  1FMW A;  2FL2 A;  3ZFD A;  3T0Q A;  3X2T A;  2HEH A;  5LT0 A;  4A51 A;  1VFV A;  3HQD A;  1T5C A;  2KIN A;  1D1C A;  1LVK A;  4BN2 A;  3K3B A;  1BR4 A;  1VFZ A;  1BR2 A;  4PFO A;  1LKX A;  4A28 A;  3L1C A;  4PJN A;  3ZFC A;  2G1Q A;  2FME A;  1F9U A;  2NCD A;  1D0X A;  2ZFJ A;  2ZFL A;  4LNU K;  4Y05 A;  2ZFM A;  3B6V A;  4E7S A;  4FRZ A;  1SDM A;  1Q0B A;  1F9T A;  4H1G A;  2GRY A;  4PJM A;  4AP0 A;  1VFW A;  1G8X A;  2VVG A;  4PJJ A;  4ETP A;  3ZCW A;  2X7C A;  4A50 A;  1I6I A;  2X7D A;  2Y5W A;  3LRE A;  1CZ7 A;  1X88 A;  3B6U A;  2Q2Z A;  3GBJ A;  3KAR A;  1D1B A;  5LT3 A;  4DBR A;  3KEN A;  4DBQ A;  5LT1 A;  2IEH A;  1GOJ A;  1RY6 A;  2VB6 A;  2XAE A;  5GSZ A;  3WPN A;  1D0Z A;  2Y65 A;  1BG2 A;  4HNA K;  1MMD A;  3CNZ A;  4A14 A;  4AS7 A; 
#chains in the Genus database with same CATH topology
 2FKY A;  2X2R A;  1VOM A;  1VFX A;  1V8K A;  1BR1 A;  3DC4 A;  4A5Y A;  3PXN A;  3L9H A;  3BFN A;  2X51 A;  5HLE A;  1N6M A;  4E7Z A;  2WOG A;  3K5E A;  2ZFI A;  3KIN A;  1II6 A;  4PJL A;  1MMA A;  4A1Z A;  3U06 A;  4PFP A;  1MKJ A;  1F9W A;  5LT4 A;  2X7E A;  4ANJ A;  1YRS A;  1D0Y A;  1V8J A;  2FL6 A;  4B7B A;  1MMG A;  4GKR A;  2XT3 A;  4BBG A;  4BXN A;  1MNE A;  2VAS A;  4GKQ A;  4ZCA A;  4UBF A;  2UYM A;  3COB A;  1FMV A;  3WRD A;  1F9V A;  1D1A A;  1MMN A;  2V26 A;  2GM1 A;  2Q2Y A;  2ZFK A;  3CJO A;  1KK7 A;  5LT2 A;  2PG2 A;  4ZHI A;  3H4S A;  1I5S A;  3DCB A;  2UYI A;  2OWM A;  3NWN A;  4PK4 A;  2MYS A;  1FMW A;  2FL2 A;  3ZFD A;  3T0Q A;  3X2T A;  2HEH A;  5LT0 A;  4A51 A;  1VFV A;  4ETP B;  3HQD A;  1T5C A;  2KIN A;  1D1C A;  1LVK A;  4BN2 A;  3K3B A;  1BR4 A;  1VFZ A;  1BR2 A;  4PFO A;  1LKX A;  4A28 A;  3L1C A;  4PJN A;  3ZFC A;  2G1Q A;  2FME A;  1F9U A;  2NCD A;  1D0X A;  2ZFJ A;  2ZFL A;  4LNU K;  4Y05 A;  2ZFM A;  3B6V A;  4E7S A;  4FRZ A;  1SDM A;  1Q0B A;  1F9T A;  4H1G A;  2GRY A;  4PJM A;  4AP0 A;  1VFW A;  1G8X A;  2VVG A;  4PJJ A;  4ETP A;  3ZCW A;  2X7C A;  4A50 A;  1I6I A;  2X7D A;  2Y5W A;  3LRE A;  1CZ7 A;  1X88 A;  3B6U A;  2Q2Z A;  3GBJ A;  3KAR A;  1D1B A;  5LT3 A;  4DBR A;  3KEN A;  4DBQ A;  5LT1 A;  2IEH A;  1GOJ A;  1RY6 A;  2VB6 A;  2XAE A;  5GSZ A;  3WPN A;  1D0Z A;  2Y65 A;  2O0A A;  4GKP A;  1BG2 A;  4HNA K;  1MMD A;  3CNZ A;  4A14 A;  4AS7 A; 
#chains in the Genus database with same CATH homology
 2FKY A;  2X2R A;  1VOM A;  1VFX A;  1V8K A;  1BR1 A;  3DC4 A;  4A5Y A;  3PXN A;  3L9H A;  3BFN A;  2X51 A;  5HLE A;  1N6M A;  4E7Z A;  2WOG A;  3K5E A;  2ZFI A;  3KIN A;  1II6 A;  4PJL A;  1MMA A;  4A1Z A;  3U06 A;  4PFP A;  1MKJ A;  1F9W A;  5LT4 A;  2X7E A;  4ANJ A;  1YRS A;  1D0Y A;  1V8J A;  2FL6 A;  4B7B A;  1MMG A;  4GKR A;  2XT3 A;  4BBG A;  4BXN A;  1MNE A;  2VAS A;  4ZCA A;  4UBF A;  2UYM A;  3COB A;  1FMV A;  3WRD A;  1F9V A;  1D1A A;  1MMN A;  2V26 A;  2GM1 A;  2Q2Y A;  2ZFK A;  3CJO A;  1KK7 A;  5LT2 A;  2PG2 A;  4ZHI A;  3H4S A;  1I5S A;  3DCB A;  2UYI A;  2OWM A;  3NWN A;  4PK4 A;  2MYS A;  1FMW A;  2FL2 A;  3ZFD A;  3T0Q A;  3X2T A;  2HEH A;  5LT0 A;  4A51 A;  1VFV A;  3HQD A;  1T5C A;  2KIN A;  1D1C A;  1LVK A;  4BN2 A;  3K3B A;  1BR4 A;  1VFZ A;  1BR2 A;  4PFO A;  1LKX A;  4A28 A;  3L1C A;  4PJN A;  3ZFC A;  2G1Q A;  2FME A;  1F9U A;  2NCD A;  1D0X A;  2ZFJ A;  2ZFL A;  4LNU K;  4Y05 A;  2ZFM A;  3B6V A;  4E7S A;  4FRZ A;  1SDM A;  1Q0B A;  1F9T A;  4H1G A;  2GRY A;  4PJM A;  4AP0 A;  1VFW A;  1G8X A;  2VVG A;  4PJJ A;  4ETP A;  3ZCW A;  2X7C A;  4A50 A;  1I6I A;  2X7D A;  2Y5W A;  3LRE A;  1CZ7 A;  1X88 A;  3B6U A;  2Q2Z A;  3GBJ A;  3KAR A;  1D1B A;  5LT3 A;  4DBR A;  3KEN A;  4DBQ A;  5LT1 A;  2IEH A;  1GOJ A;  1RY6 A;  2VB6 A;  2XAE A;  5GSZ A;  3WPN A;  1D0Z A;  2Y65 A;  1BG2 A;  4HNA K;  1MMD A;  3CNZ A;  4A14 A;  4AS7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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