1F9VA

Crystal structures of mutants reveal a signalling pathway for activation of the kinesin motor atpase
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
342
structure length
313
Chain Sequence
GNIRVYCRIRPALKNLENSDTSLINVNEFDDNSGVQSMEVTKIQNTAQVHEFKFDKIFDQQDTNVDVFKEVGQLVQSSLDGYNVCIFAYGQTGSGKTFTMLNPGDGIIPSTISHIFNWINKLKTKGWDYKVNCEFIEIYNENIVDLLRKHEIRHDQETKTTTITNVTSCKLESEEMVEIILKKANEHSSASHSIFIIHLSGSNAGAHSYGTLNLVDLAGSERINVSQVVGDRLRETQNINKSLSCLGDVIHALGQPDRHIPFRNSKLTYLLQYSLTGDSKTLMFVNISPSSSHINETLNSLRFASKVNSTRLV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords KINESIN-LIKE PROTEIN KAR3
publication title A structural pathway for activation of the kinesin motor ATPase.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
molecule tags Contractile protein
total genus 105
structure length 313
sequence length 342
ec nomenclature
pdb deposition date 2000-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 1f9vA00
3KINA 1F9TA 3WPNA 2MYSA 1D1CA 2V26A 3ZFDA 3LREA 4BXNA 2UYIA 2FMEA 4E7SA 4ANJA 2FL2A 4HNAK 3HQDA 1MMDA 1VOMA 1GOJA 5GSZA 4A5YA 2GM1A 1T5CA 3PXNA 1V8JA 2WOGA 2KINA 4AP0A 2VB6A 4DBRA 1YRSA 1VFVA 2ZFJA 1F9UA 1V8KA 1MMAA 2FKYA 3DCBA 3K5EA 4ZCAA 4B7BA 1MMGA 4ETPA 1D1BA 4PFPA 4PJNA 4A1ZA 4LNUK 1D0YA 3DC4A 4BBGA 5LT0A 4PJMA 1N6MA 3COBA 1F9WA 1D0XA 5LT1A 3H4SA 2G1QA 4UBFA 3L1CA 1F9VA 1BR4A 4Y05A 2Y5WA 3ZCWA 1BR2A 3B6UA 1VFXA 5LT2A 2ZFIA 4DBQA 2XAEA 2NCDA 2Q2YA 2GRYA 1MMNA 4FRZA 2X51A 1X88A 2PG2A 1Q0BA 1I6IA 3WRDA 3CJOA 2FL6A 3KARA 3U06A 5LT3A 1LKXA 1CZ7A 3GBJA 2XT3A 1BG2A 2X7DA 5HLEA 3X2TA 1MKJA 4BN2A 4GKRA 4PJLA 1BR1A 4A14A 4ZHIA 1RY6A 1LVKA 2X7CA 3NWNA 1KK7A 2ZFMA 1II6A 4E7ZA 3B6VA 3ZFCA 3L9HA 5LT4A 4AS7A 2OWMA 4A28A 1FMVA 2ZFLA 1VFWA 2ZFKA 3T0QA 2VVGA 4A50A 1I5SA 4PFOA 2HEHA 3BFNA 1SDMA 3KENA 1MNEA 1D0ZA 2Q2ZA 2Y65A 3K3BA 2X2RA 4PK4A 2UYMA 1G8XA 3CNZA 1D1AA 2VASA 1FMWA 1VFZA 4A51A 4PJJA 2X7EA 4H1GA 2IEHA
chains in the Genus database with same CATH superfamily
3KINA 1F9TA 3WPNA 4GKQA 2MYSA 1D1CA 2V26A 3ZFDA 3LREA 4BXNA 2UYIA 2FMEA 4E7SA 4ANJA 2FL2A 4HNAK 3HQDA 1MMDA 1VOMA 4GKPA 1GOJA 5GSZA 4A5YA 2GM1A 1T5CA 3PXNA 1V8JA 2WOGA 2KINA 4AP0A 2VB6A 4DBRA 1YRSA 1VFVA 2ZFJA 1F9UA 1V8KA 1MMAA 2FKYA 3DCBA 3K5EA 4ZCAA 4B7BA 1MMGA 4ETPA 1D1BA 4PFPA 4PJNA 4A1ZA 4LNUK 1D0YA 3DC4A 4BBGA 5LT0A 4PJMA 1N6MA 3COBA 1F9WA 1D0XA 5LT1A 3H4SA 2G1QA 4UBFA 3L1CA 1F9VA 1BR4A 4Y05A 2Y5WA 3ZCWA 1BR2A 3B6UA 1VFXA 5LT2A 2ZFIA 4DBQA 2XAEA 2NCDA 2Q2YA 2GRYA 1MMNA 4FRZA 2X51A 1X88A 2PG2A 1Q0BA 1I6IA 3WRDA 3CJOA 2FL6A 3KARA 3U06A 5LT3A 1LKXA 1CZ7A 3GBJA 2XT3A 1BG2A 2X7DA 5HLEA 3X2TA 1MKJA 4ETPB 4BN2A 4GKRA 4PJLA 1BR1A 4A14A 4ZHIA 1RY6A 1LVKA 2X7CA 3NWNA 1KK7A 2ZFMA 1II6A 4E7ZA 3B6VA 3ZFCA 3L9HA 5LT4A 4AS7A 2OWMA 4A28A 1FMVA 2ZFLA 1VFWA 2ZFKA 3T0QA 2VVGA 4A50A 1I5SA 4PFOA 2HEHA 3BFNA 1SDMA 3KENA 1MNEA 1D0ZA 2Q2ZA 2Y65A 3K3BA 2O0AA 2X2RA 4PK4A 2UYMA 1G8XA 3CNZA 1D1AA 2VASA 1FMWA 1VFZA 4A51A 4PJJA 2X7EA 4H1GA 2IEHA
chains in the Genus database with same CATH topology
3KINA 1F9TA 3WPNA 2MYSA 1D1CA 2V26A 3ZFDA 3LREA 4BXNA 2UYIA 2FMEA 4E7SA 4ANJA 2FL2A 4HNAK 3HQDA 1MMDA 1VOMA 1GOJA 5GSZA 4A5YA 2GM1A 1T5CA 3PXNA 1V8JA 2WOGA 2KINA 4AP0A 2VB6A 4DBRA 1YRSA 1VFVA 2ZFJA 1F9UA 1V8KA 1MMAA 2FKYA 3DCBA 3K5EA 4ZCAA 4B7BA 1MMGA 4ETPA 1D1BA 4PFPA 4PJNA 4A1ZA 4LNUK 1D0YA 3DC4A 4BBGA 5LT0A 4PJMA 1N6MA 3COBA 1F9WA 1D0XA 5LT1A 3H4SA 2G1QA 4UBFA 3L1CA 1F9VA 1BR4A 4Y05A 2Y5WA 3ZCWA 1BR2A 3B6UA 1VFXA 5LT2A 2ZFIA 4DBQA 2XAEA 2NCDA 2Q2YA 2GRYA 1MMNA 4FRZA 2X51A 1X88A 2PG2A 1Q0BA 1I6IA 3WRDA 3CJOA 2FL6A 3KARA 3U06A 5LT3A 1LKXA 1CZ7A 3GBJA 2XT3A 1BG2A 2X7DA 5HLEA 3X2TA 1MKJA 4BN2A 4GKRA 4PJLA 1BR1A 4A14A 4ZHIA 1RY6A 1LVKA 2X7CA 3NWNA 1KK7A 2ZFMA 1II6A 4E7ZA 3B6VA 3ZFCA 3L9HA 5LT4A 4AS7A 2OWMA 4A28A 1FMVA 2ZFLA 1VFWA 2ZFKA 3T0QA 2VVGA 4A50A 1I5SA 4PFOA 2HEHA 3BFNA 1SDMA 3KENA 1MNEA 1D0ZA 2Q2ZA 2Y65A 3K3BA 2X2RA 4PK4A 2UYMA 1G8XA 3CNZA 1D1AA 2VASA 1FMWA 1VFZA 4A51A 4PJJA 2X7EA 4H1GA 2IEHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KIN A;  1F9T A;  3WPN A;  2MYS A;  1D1C A;  2V26 A;  3ZFD A;  3LRE A;  4BXN A;  2UYI A;  2FME A;  4E7S A;  4ANJ A;  2FL2 A;  4HNA K;  3HQD A;  1MMD A;  1VOM A;  1GOJ A;  5GSZ A;  4A5Y A;  2GM1 A;  1T5C A;  3PXN A;  1V8J A;  2WOG A;  2KIN A;  4AP0 A;  2VB6 A;  4DBR A;  1YRS A;  1VFV A;  2ZFJ A;  1F9U A;  1V8K A;  1MMA A;  2FKY A;  3DCB A;  3K5E A;  4ZCA A;  4B7B A;  1MMG A;  4ETP A;  1D1B A;  4PFP A;  4PJN A;  4A1Z A;  4LNU K;  1D0Y A;  3DC4 A;  4BBG A;  5LT0 A;  4PJM A;  1N6M A;  3COB A;  1F9W A;  1D0X A;  5LT1 A;  3H4S A;  2G1Q A;  4UBF A;  3L1C A;  1F9V A;  1BR4 A;  4Y05 A;  2Y5W A;  3ZCW A;  1BR2 A;  3B6U A;  1VFX A;  5LT2 A;  2ZFI A;  4DBQ A;  2XAE A;  2NCD A;  2Q2Y A;  2GRY A;  1MMN A;  4FRZ A;  2X51 A;  1X88 A;  2PG2 A;  1Q0B A;  1I6I A;  3WRD A;  3CJO A;  2FL6 A;  3KAR A;  3U06 A;  5LT3 A;  1LKX A;  1CZ7 A;  3GBJ A;  2XT3 A;  1BG2 A;  2X7D A;  5HLE A;  3X2T A;  1MKJ A;  4BN2 A;  4GKR A;  4PJL A;  1BR1 A;  4A14 A;  4ZHI A;  1RY6 A;  1LVK A;  2X7C A;  3NWN A;  1KK7 A;  2ZFM A;  1II6 A;  4E7Z A;  3B6V A;  3ZFC A;  3L9H A;  5LT4 A;  4AS7 A;  2OWM A;  4A28 A;  1FMV A;  2ZFL A;  1VFW A;  2ZFK A;  3T0Q A;  2VVG A;  4A50 A;  1I5S A;  4PFO A;  2HEH A;  3BFN A;  1SDM A;  3KEN A;  1MNE A;  1D0Z A;  2Q2Z A;  2Y65 A;  3K3B A;  2X2R A;  4PK4 A;  2UYM A;  1G8X A;  3CNZ A;  1D1A A;  2VAS A;  1FMW A;  1VFZ A;  4A51 A;  4PJJ A;  2X7E A;  4H1G A;  2IEH A; 
#chains in the Genus database with same CATH topology
 3KIN A;  1F9T A;  3WPN A;  4GKQ A;  2MYS A;  1D1C A;  2V26 A;  3ZFD A;  3LRE A;  4BXN A;  2UYI A;  2FME A;  4E7S A;  4ANJ A;  2FL2 A;  4HNA K;  3HQD A;  1MMD A;  1VOM A;  4GKP A;  1GOJ A;  5GSZ A;  4A5Y A;  2GM1 A;  1T5C A;  3PXN A;  1V8J A;  2WOG A;  2KIN A;  4AP0 A;  2VB6 A;  4DBR A;  1YRS A;  1VFV A;  2ZFJ A;  1F9U A;  1V8K A;  1MMA A;  2FKY A;  3DCB A;  3K5E A;  4ZCA A;  4B7B A;  1MMG A;  4ETP A;  1D1B A;  4PFP A;  4PJN A;  4A1Z A;  4LNU K;  1D0Y A;  3DC4 A;  4BBG A;  5LT0 A;  4PJM A;  1N6M A;  3COB A;  1F9W A;  1D0X A;  5LT1 A;  3H4S A;  2G1Q A;  4UBF A;  3L1C A;  1F9V A;  1BR4 A;  4Y05 A;  2Y5W A;  3ZCW A;  1BR2 A;  3B6U A;  1VFX A;  5LT2 A;  2ZFI A;  4DBQ A;  2XAE A;  2NCD A;  2Q2Y A;  2GRY A;  1MMN A;  4FRZ A;  2X51 A;  1X88 A;  2PG2 A;  1Q0B A;  1I6I A;  3WRD A;  3CJO A;  2FL6 A;  3KAR A;  3U06 A;  5LT3 A;  1LKX A;  1CZ7 A;  3GBJ A;  2XT3 A;  1BG2 A;  2X7D A;  5HLE A;  3X2T A;  1MKJ A;  4ETP B;  4BN2 A;  4GKR A;  4PJL A;  1BR1 A;  4A14 A;  4ZHI A;  1RY6 A;  1LVK A;  2X7C A;  3NWN A;  1KK7 A;  2ZFM A;  1II6 A;  4E7Z A;  3B6V A;  3ZFC A;  3L9H A;  5LT4 A;  4AS7 A;  2OWM A;  4A28 A;  1FMV A;  2ZFL A;  1VFW A;  2ZFK A;  3T0Q A;  2VVG A;  4A50 A;  1I5S A;  4PFO A;  2HEH A;  3BFN A;  1SDM A;  3KEN A;  1MNE A;  1D0Z A;  2Q2Z A;  2Y65 A;  3K3B A;  2O0A A;  2X2R A;  4PK4 A;  2UYM A;  1G8X A;  3CNZ A;  1D1A A;  2VAS A;  1FMW A;  1VFZ A;  4A51 A;  4PJJ A;  2X7E A;  4H1G A;  2IEH A; 
#chains in the Genus database with same CATH homology
 3KIN A;  1F9T A;  3WPN A;  2MYS A;  1D1C A;  2V26 A;  3ZFD A;  3LRE A;  4BXN A;  2UYI A;  2FME A;  4E7S A;  4ANJ A;  2FL2 A;  4HNA K;  3HQD A;  1MMD A;  1VOM A;  1GOJ A;  5GSZ A;  4A5Y A;  2GM1 A;  1T5C A;  3PXN A;  1V8J A;  2WOG A;  2KIN A;  4AP0 A;  2VB6 A;  4DBR A;  1YRS A;  1VFV A;  2ZFJ A;  1F9U A;  1V8K A;  1MMA A;  2FKY A;  3DCB A;  3K5E A;  4ZCA A;  4B7B A;  1MMG A;  4ETP A;  1D1B A;  4PFP A;  4PJN A;  4A1Z A;  4LNU K;  1D0Y A;  3DC4 A;  4BBG A;  5LT0 A;  4PJM A;  1N6M A;  3COB A;  1F9W A;  1D0X A;  5LT1 A;  3H4S A;  2G1Q A;  4UBF A;  3L1C A;  1F9V A;  1BR4 A;  4Y05 A;  2Y5W A;  3ZCW A;  1BR2 A;  3B6U A;  1VFX A;  5LT2 A;  2ZFI A;  4DBQ A;  2XAE A;  2NCD A;  2Q2Y A;  2GRY A;  1MMN A;  4FRZ A;  2X51 A;  1X88 A;  2PG2 A;  1Q0B A;  1I6I A;  3WRD A;  3CJO A;  2FL6 A;  3KAR A;  3U06 A;  5LT3 A;  1LKX A;  1CZ7 A;  3GBJ A;  2XT3 A;  1BG2 A;  2X7D A;  5HLE A;  3X2T A;  1MKJ A;  4BN2 A;  4GKR A;  4PJL A;  1BR1 A;  4A14 A;  4ZHI A;  1RY6 A;  1LVK A;  2X7C A;  3NWN A;  1KK7 A;  2ZFM A;  1II6 A;  4E7Z A;  3B6V A;  3ZFC A;  3L9H A;  5LT4 A;  4AS7 A;  2OWM A;  4A28 A;  1FMV A;  2ZFL A;  1VFW A;  2ZFK A;  3T0Q A;  2VVG A;  4A50 A;  1I5S A;  4PFO A;  2HEH A;  3BFN A;  1SDM A;  3KEN A;  1MNE A;  1D0Z A;  2Q2Z A;  2Y65 A;  3K3B A;  2X2R A;  4PK4 A;  2UYM A;  1G8X A;  3CNZ A;  1D1A A;  2VAS A;  1FMW A;  1VFZ A;  4A51 A;  4PJJ A;  2X7E A;  4H1G A;  2IEH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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