1F9VA

Crystal structures of mutants reveal a signalling pathway for activation of the kinesin motor atpase
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
342
structure length
313
Chain Sequence
GNIRVYCRIRPALKNLENSDTSLINVNEFDDNSGVQSMEVTKIQNTAQVHEFKFDKIFDQQDTNVDVFKEVGQLVQSSLDGYNVCIFAYGQTGSGKTFTMLNPGDGIIPSTISHIFNWINKLKTKGWDYKVNCEFIEIYNENIVDLLRKHEIRHDQETKTTTITNVTSCKLESEEMVEIILKKANEHSSASHSIFIIHLSGSNAGAHSYGTLNLVDLAGSERINVSQVVGDRLRETQNINKSLSCLGDVIHALGQPDRHIPFRNSKLTYLLQYSLTGDSKTLMFVNISPSSSHINETLNSLRFASKVNSTRLV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A structural pathway for activation of the kinesin motor ATPase.
pubmed doi rcsb
molecule tags Contractile protein
source organism Saccharomyces cerevisiae
molecule keywords KINESIN-LIKE PROTEIN KAR3
total genus 105
structure length 313
sequence length 342
ec nomenclature
pdb deposition date 2000-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 1f9vA00
4PJNA 4A28A 2X7DA 1FMWA 4Y05A 4A50A 1VOMA 2FMEA 1BR4A 2ZFJA 3DCBA 2ZFLA 4PJMA 1D0ZA 1RY6A 1I5SA 1F9TA 2V26A 5GSZA 2FL6A 2X51A 2Q2YA 3CNZA 2X7EA 4AS7A 2UYIA 1F9UA 1D1BA 3T0QA 1GOJA 1G8XA 1VFZA 4PK4A 3U06A 2VASA 5HLEA 1LVKA 1FMVA 1VFVA 4A1ZA 1MMGA 4ZHIA 4B7BA 2ZFMA 3K3BA 5LT0A 2PG2A 3ZCWA 2KINA 2VB6A 1F9VA 1MNEA 3X2TA 1V8JA 2Y5WA 3KARA 3WRDA 1MMDA 4DBQA 1MMAA 4DBRA 4E7ZA 5LT3A 3B6UA 2ZFIA 5LT1A 1VFXA 2GRYA 4A51A 1V8KA 2HEHA 2VVGA 2NCDA 2FKYA 4PFPA 4A14A 1LKXA 3DC4A 2X2RA 4HNAK 4FRZA 3B6VA 3KENA 1MMNA 3L1CA 1VFWA 1II6A 4GKRA 1SDMA 4UBFA 1BR1A 3COBA 4PFOA 4ZCAA 1CZ7A 1BR2A 2FL2A 2Y65A 1MKJA 1I6IA 3L9HA 3PXNA 2X7CA 3BFNA 1D1AA 2Q2ZA 2GM1A 2UYMA 3NWNA 4H1GA 3LREA 1F9WA 2G1QA 3H4SA 4BXNA 1BG2A 4AP0A 3HQDA 4A5YA 3KINA 3WPNA 1X88A 1Q0BA 5LT4A 4BBGA 1T5CA 1D1CA 2XT3A 2WOGA 1N6MA 3ZFCA 3ZFDA 4ETPA 1D0YA 3CJOA 3GBJA 4PJLA 2MYSA 4E7SA 3K5EA 2IEHA 4PJJA 4BN2A 1YRSA 1KK7A 4ANJA 1D0XA 2ZFKA 4LNUK 2XAEA 5LT2A 2OWMA
chains in the Genus database with same CATH superfamily
4PJNA 4A28A 2X7DA 1FMWA 4Y05A 4A50A 1VOMA 2FMEA 1BR4A 2ZFJA 3DCBA 2ZFLA 4PJMA 1D0ZA 1RY6A 1I5SA 1F9TA 2V26A 5GSZA 2FL6A 2X51A 2Q2YA 3CNZA 2X7EA 4AS7A 2UYIA 1F9UA 1D1BA 3T0QA 1GOJA 1G8XA 1VFZA 4PK4A 3U06A 2VASA 5HLEA 1LVKA 1FMVA 1VFVA 4A1ZA 1MMGA 4ZHIA 4B7BA 2ZFMA 3K3BA 5LT0A 2PG2A 3ZCWA 2KINA 2VB6A 1F9VA 1MNEA 3X2TA 1V8JA 2Y5WA 3KARA 3WRDA 1MMDA 4DBQA 1MMAA 4DBRA 4E7ZA 5LT3A 3B6UA 2ZFIA 5LT1A 1VFXA 2GRYA 4A51A 1V8KA 2HEHA 2O0AA 2VVGA 2NCDA 2FKYA 4PFPA 4A14A 1LKXA 4GKPA 3DC4A 2X2RA 4HNAK 4FRZA 3B6VA 3KENA 1MMNA 3L1CA 4GKQA 1VFWA 1II6A 4GKRA 1SDMA 4UBFA 1BR1A 3COBA 4PFOA 4ZCAA 1CZ7A 1BR2A 2FL2A 2Y65A 1MKJA 1I6IA 3L9HA 3PXNA 2X7CA 3BFNA 2Q2ZA 1D1AA 2GM1A 2UYMA 3NWNA 4H1GA 3LREA 1F9WA 2G1QA 3H4SA 4BXNA 1BG2A 4AP0A 3HQDA 4A5YA 3KINA 3WPNA 1X88A 1Q0BA 5LT4A 4BBGA 1T5CA 1D1CA 2XT3A 2WOGA 1N6MA 3ZFCA 3ZFDA 4ETPA 1D0YA 3CJOA 3GBJA 4PJLA 2MYSA 4E7SA 3K5EA 2IEHA 4PJJA 4ETPB 4BN2A 1YRSA 1KK7A 4ANJA 1D0XA 2ZFKA 4LNUK 2XAEA 5LT2A 2OWMA
chains in the Genus database with same CATH topology
4PJNA 4A28A 2X7DA 1FMWA 4Y05A 4A50A 1VOMA 2FMEA 1BR4A 2ZFJA 3DCBA 2ZFLA 4PJMA 1D0ZA 1RY6A 1I5SA 1F9TA 2V26A 5GSZA 2FL6A 2X51A 2Q2YA 3CNZA 2X7EA 4AS7A 2UYIA 1F9UA 1D1BA 3T0QA 1GOJA 1G8XA 1VFZA 4PK4A 3U06A 2VASA 5HLEA 1LVKA 1FMVA 1VFVA 4A1ZA 1MMGA 4ZHIA 4B7BA 2ZFMA 3K3BA 5LT0A 2PG2A 3ZCWA 2KINA 2VB6A 1F9VA 1MNEA 3X2TA 1V8JA 2Y5WA 3KARA 3WRDA 1MMDA 4DBQA 1MMAA 4DBRA 4E7ZA 5LT3A 3B6UA 2ZFIA 5LT1A 1VFXA 2GRYA 4A51A 1V8KA 2HEHA 2VVGA 2NCDA 2FKYA 4PFPA 4A14A 1LKXA 3DC4A 2X2RA 4HNAK 4FRZA 3B6VA 3KENA 1MMNA 3L1CA 1VFWA 1II6A 4GKRA 1SDMA 4UBFA 1BR1A 3COBA 4PFOA 4ZCAA 1CZ7A 1BR2A 2FL2A 2Y65A 1MKJA 1I6IA 3L9HA 3PXNA 2X7CA 3BFNA 1D1AA 2Q2ZA 2GM1A 2UYMA 3NWNA 4H1GA 3LREA 1F9WA 2G1QA 3H4SA 4BXNA 1BG2A 4AP0A 3HQDA 4A5YA 3KINA 3WPNA 1X88A 1Q0BA 5LT4A 4BBGA 1T5CA 1D1CA 2XT3A 2WOGA 1N6MA 3ZFCA 3ZFDA 4ETPA 1D0YA 3CJOA 3GBJA 4PJLA 2MYSA 4E7SA 3K5EA 2IEHA 4PJJA 4BN2A 1YRSA 1KK7A 4ANJA 1D0XA 2ZFKA 4LNUK 2XAEA 5LT2A 2OWMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PJN A;  4A28 A;  2X7D A;  1FMW A;  4Y05 A;  4A50 A;  1VOM A;  2FME A;  1BR4 A;  2ZFJ A;  3DCB A;  2ZFL A;  4PJM A;  1D0Z A;  1RY6 A;  1I5S A;  1F9T A;  2V26 A;  5GSZ A;  2FL6 A;  2X51 A;  2Q2Y A;  3CNZ A;  2X7E A;  4AS7 A;  2UYI A;  1F9U A;  1D1B A;  3T0Q A;  1GOJ A;  1G8X A;  1VFZ A;  4PK4 A;  3U06 A;  2VAS A;  5HLE A;  1LVK A;  1FMV A;  1VFV A;  4A1Z A;  1MMG A;  4ZHI A;  4B7B A;  2ZFM A;  3K3B A;  5LT0 A;  2PG2 A;  3ZCW A;  2KIN A;  2VB6 A;  1F9V A;  1MNE A;  3X2T A;  1V8J A;  2Y5W A;  3KAR A;  3WRD A;  1MMD A;  4DBQ A;  1MMA A;  4DBR A;  4E7Z A;  5LT3 A;  3B6U A;  2ZFI A;  5LT1 A;  1VFX A;  2GRY A;  4A51 A;  1V8K A;  2HEH A;  2VVG A;  2NCD A;  2FKY A;  4PFP A;  4A14 A;  1LKX A;  3DC4 A;  2X2R A;  4HNA K;  4FRZ A;  3B6V A;  3KEN A;  1MMN A;  3L1C A;  1VFW A;  1II6 A;  4GKR A;  1SDM A;  4UBF A;  1BR1 A;  3COB A;  4PFO A;  4ZCA A;  1CZ7 A;  1BR2 A;  2FL2 A;  2Y65 A;  1MKJ A;  1I6I A;  3L9H A;  3PXN A;  2X7C A;  3BFN A;  1D1A A;  2Q2Z A;  2GM1 A;  2UYM A;  3NWN A;  4H1G A;  3LRE A;  1F9W A;  2G1Q A;  3H4S A;  4BXN A;  1BG2 A;  4AP0 A;  3HQD A;  4A5Y A;  3KIN A;  3WPN A;  1X88 A;  1Q0B A;  5LT4 A;  4BBG A;  1T5C A;  1D1C A;  2XT3 A;  2WOG A;  1N6M A;  3ZFC A;  3ZFD A;  4ETP A;  1D0Y A;  3CJO A;  3GBJ A;  4PJL A;  2MYS A;  4E7S A;  3K5E A;  2IEH A;  4PJJ A;  4BN2 A;  1YRS A;  1KK7 A;  4ANJ A;  1D0X A;  2ZFK A;  4LNU K;  2XAE A;  5LT2 A;  2OWM A; 
#chains in the Genus database with same CATH topology
 4PJN A;  4A28 A;  2X7D A;  1FMW A;  4Y05 A;  4A50 A;  1VOM A;  2FME A;  1BR4 A;  2ZFJ A;  3DCB A;  2ZFL A;  4PJM A;  1D0Z A;  1RY6 A;  1I5S A;  1F9T A;  2V26 A;  5GSZ A;  2FL6 A;  2X51 A;  2Q2Y A;  3CNZ A;  2X7E A;  4AS7 A;  2UYI A;  1F9U A;  1D1B A;  3T0Q A;  1GOJ A;  1G8X A;  1VFZ A;  4PK4 A;  3U06 A;  2VAS A;  5HLE A;  1LVK A;  1FMV A;  1VFV A;  4A1Z A;  1MMG A;  4ZHI A;  4B7B A;  2ZFM A;  3K3B A;  5LT0 A;  2PG2 A;  3ZCW A;  2KIN A;  2VB6 A;  1F9V A;  1MNE A;  3X2T A;  1V8J A;  2Y5W A;  3KAR A;  3WRD A;  1MMD A;  4DBQ A;  1MMA A;  4DBR A;  4E7Z A;  5LT3 A;  3B6U A;  2ZFI A;  5LT1 A;  1VFX A;  2GRY A;  4A51 A;  1V8K A;  2HEH A;  2O0A A;  2VVG A;  2NCD A;  2FKY A;  4PFP A;  4A14 A;  1LKX A;  4GKP A;  3DC4 A;  2X2R A;  4HNA K;  4FRZ A;  3B6V A;  3KEN A;  1MMN A;  3L1C A;  4GKQ A;  1VFW A;  1II6 A;  4GKR A;  1SDM A;  4UBF A;  1BR1 A;  3COB A;  4PFO A;  4ZCA A;  1CZ7 A;  1BR2 A;  2FL2 A;  2Y65 A;  1MKJ A;  1I6I A;  3L9H A;  3PXN A;  2X7C A;  3BFN A;  2Q2Z A;  1D1A A;  2GM1 A;  2UYM A;  3NWN A;  4H1G A;  3LRE A;  1F9W A;  2G1Q A;  3H4S A;  4BXN A;  1BG2 A;  4AP0 A;  3HQD A;  4A5Y A;  3KIN A;  3WPN A;  1X88 A;  1Q0B A;  5LT4 A;  4BBG A;  1T5C A;  1D1C A;  2XT3 A;  2WOG A;  1N6M A;  3ZFC A;  3ZFD A;  4ETP A;  1D0Y A;  3CJO A;  3GBJ A;  4PJL A;  2MYS A;  4E7S A;  3K5E A;  2IEH A;  4PJJ A;  4ETP B;  4BN2 A;  1YRS A;  1KK7 A;  4ANJ A;  1D0X A;  2ZFK A;  4LNU K;  2XAE A;  5LT2 A;  2OWM A; 
#chains in the Genus database with same CATH homology
 4PJN A;  4A28 A;  2X7D A;  1FMW A;  4Y05 A;  4A50 A;  1VOM A;  2FME A;  1BR4 A;  2ZFJ A;  3DCB A;  2ZFL A;  4PJM A;  1D0Z A;  1RY6 A;  1I5S A;  1F9T A;  2V26 A;  5GSZ A;  2FL6 A;  2X51 A;  2Q2Y A;  3CNZ A;  2X7E A;  4AS7 A;  2UYI A;  1F9U A;  1D1B A;  3T0Q A;  1GOJ A;  1G8X A;  1VFZ A;  4PK4 A;  3U06 A;  2VAS A;  5HLE A;  1LVK A;  1FMV A;  1VFV A;  4A1Z A;  1MMG A;  4ZHI A;  4B7B A;  2ZFM A;  3K3B A;  5LT0 A;  2PG2 A;  3ZCW A;  2KIN A;  2VB6 A;  1F9V A;  1MNE A;  3X2T A;  1V8J A;  2Y5W A;  3KAR A;  3WRD A;  1MMD A;  4DBQ A;  1MMA A;  4DBR A;  4E7Z A;  5LT3 A;  3B6U A;  2ZFI A;  5LT1 A;  1VFX A;  2GRY A;  4A51 A;  1V8K A;  2HEH A;  2VVG A;  2NCD A;  2FKY A;  4PFP A;  4A14 A;  1LKX A;  3DC4 A;  2X2R A;  4HNA K;  4FRZ A;  3B6V A;  3KEN A;  1MMN A;  3L1C A;  1VFW A;  1II6 A;  4GKR A;  1SDM A;  4UBF A;  1BR1 A;  3COB A;  4PFO A;  4ZCA A;  1CZ7 A;  1BR2 A;  2FL2 A;  2Y65 A;  1MKJ A;  1I6I A;  3L9H A;  3PXN A;  2X7C A;  3BFN A;  1D1A A;  2Q2Z A;  2GM1 A;  2UYM A;  3NWN A;  4H1G A;  3LRE A;  1F9W A;  2G1Q A;  3H4S A;  4BXN A;  1BG2 A;  4AP0 A;  3HQD A;  4A5Y A;  3KIN A;  3WPN A;  1X88 A;  1Q0B A;  5LT4 A;  4BBG A;  1T5C A;  1D1C A;  2XT3 A;  2WOG A;  1N6M A;  3ZFC A;  3ZFD A;  4ETP A;  1D0Y A;  3CJO A;  3GBJ A;  4PJL A;  2MYS A;  4E7S A;  3K5E A;  2IEH A;  4PJJ A;  4BN2 A;  1YRS A;  1KK7 A;  4ANJ A;  1D0X A;  2ZFK A;  4LNU K;  2XAE A;  5LT2 A;  2OWM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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