2Y65A

Crystal structure of drosophila melanogaster kinesin-1 motor domain dimer-tail complex
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
344
structure length
328
Chain Sequence
PAEDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIAGKVYLFDKVFKPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDIFNHIYAMEVNLEFHIKVSYYEIYMDKIRDLLDVSKVNLSVHEDKNRVPYVKGATERFVSSPEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLINVKQENLENQKKLSGKLYLVDLAGSEKINKSLSALGNVISALADGNKTHIPYRDSKLTRILQESLGGNARTTIVICCSPASFNESETKSTLDFGRRAKTVKNVVCVNEELTAEEWKRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords KINESIN HEAVY CHAIN
publication title The Structure of the Kinesin-1 Motor-Tail Complex Reveals the Mechanism of Autoinhibition.
pubmed doi rcsb
source organism Drosophila melanogaster
molecule tags Motor protein
total genus 108
structure length 328
sequence length 344
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2011-01-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 2y65A00
5HLEA 2GM1A 4A51A 2HEHA 1D1BA 1LKXA 2XAEA 3B6VA 4AS7A 2MYSA 1LVKA 1KK7A 2IEHA 1V8KA 3U06A 4PJMA 4ZCAA 3K5EA 4A5YA 3B6UA 3CNZA 5LT4A 2WOGA 4HNAK 4ANJA 1VFVA 2ZFKA 2NCDA 3PXNA 2PG2A 4PK4A 3HQDA 2Y65A 2X7EA 3X2TA 1D0XA 1VFXA 4PFOA 5LT2A 1BG2A 4A14A 2X7DA 3K3BA 1MNEA 4GKRA 4E7SA 4ETPA 4LNUK 2ZFMA 1FMWA 2OWMA 3KENA 3BFNA 1VFWA 2X7CA 2XT3A 5LT1A 1F9TA 1BR4A 1V8JA 1VFZA 4PJNA 1BR1A 2FL2A 3WRDA 3T0QA 1D1AA 2ZFLA 1BR2A 2VB6A 4E7ZA 1D0YA 1MMGA 2V26A 1MMNA 3L9HA 4A1ZA 4BN2A 4PFPA 2UYIA 3KINA 4AP0A 1I6IA 2Q2ZA 1MMDA 3KARA 4H1GA 4A50A 2ZFIA 2FL6A 1I5SA 1RY6A 1GOJA 3ZCWA 2FKYA 3CJOA 2KINA 2ZFJA 4FRZA 1F9WA 2X2RA 3GBJA 3DC4A 3DCBA 2FMEA 2VASA 1F9VA 4DBRA 4ZHIA 1F9UA 3LREA 4DBQA 4Y05A 3ZFCA 1MKJA 1II6A 3NWNA 1VOMA 4B7BA 2Y5WA 2GRYA 1D1CA 4PJJA 1MMAA 3COBA 1YRSA 1G8XA 1X88A 4PJLA 3WPNA 1Q0BA 1T5CA 2Q2YA 5LT0A 4UBFA 4A28A 3L1CA 1D0ZA 5GSZA 3ZFDA 1N6MA 2UYMA 5LT3A 3H4SA 4BXNA 2VVGA 1CZ7A 1FMVA 2X51A 4BBGA 1SDMA 2G1QA
chains in the Genus database with same CATH superfamily
5HLEA 2O0AA 2GM1A 4A51A 2HEHA 1D1BA 1LKXA 2XAEA 3B6VA 4AS7A 2MYSA 1LVKA 1KK7A 2IEHA 1V8KA 3U06A 4PJMA 4ZCAA 3K5EA 4A5YA 3B6UA 3CNZA 5LT4A 2WOGA 4HNAK 4ANJA 1VFVA 2ZFKA 2NCDA 3PXNA 2PG2A 4PK4A 3HQDA 2Y65A 2X7EA 3X2TA 1D0XA 1VFXA 4PFOA 5LT2A 1BG2A 4A14A 2X7DA 3K3BA 1MNEA 4GKRA 4E7SA 4ETPA 4LNUK 2ZFMA 1FMWA 2OWMA 3KENA 3BFNA 1VFWA 2X7CA 2XT3A 5LT1A 1F9TA 1BR4A 1V8JA 1VFZA 4PJNA 1BR1A 2FL2A 4ETPB 3WRDA 3T0QA 1D1AA 2ZFLA 1BR2A 2VB6A 4E7ZA 1D0YA 1MMGA 2V26A 1MMNA 3L9HA 4A1ZA 4BN2A 4PFPA 2UYIA 3KINA 4GKPA 4AP0A 1I6IA 2Q2ZA 1MMDA 3KARA 4H1GA 4A50A 2ZFIA 2FL6A 1I5SA 1RY6A 1GOJA 3ZCWA 2FKYA 3CJOA 2KINA 2ZFJA 4FRZA 1F9WA 2X2RA 3GBJA 3DC4A 3DCBA 2FMEA 2VASA 1F9VA 4DBRA 4ZHIA 1F9UA 3LREA 4DBQA 4Y05A 3ZFCA 1MKJA 1II6A 3NWNA 1VOMA 4B7BA 2Y5WA 2GRYA 1D1CA 4PJJA 1MMAA 3COBA 1YRSA 1G8XA 1X88A 4PJLA 3WPNA 1Q0BA 1T5CA 2Q2YA 5LT0A 4UBFA 4A28A 3L1CA 1D0ZA 5GSZA 3ZFDA 1N6MA 2UYMA 5LT3A 3H4SA 4BXNA 2VVGA 1CZ7A 1FMVA 4GKQA 2X51A 4BBGA 1SDMA 2G1QA
chains in the Genus database with same CATH topology
5HLEA 2GM1A 4A51A 2HEHA 1D1BA 1LKXA 2XAEA 3B6VA 4AS7A 2MYSA 1LVKA 1KK7A 2IEHA 1V8KA 3U06A 4PJMA 4ZCAA 3K5EA 4A5YA 3B6UA 3CNZA 5LT4A 2WOGA 4HNAK 4ANJA 1VFVA 2ZFKA 2NCDA 3PXNA 2PG2A 4PK4A 3HQDA 2Y65A 2X7EA 3X2TA 1D0XA 1VFXA 4PFOA 5LT2A 1BG2A 4A14A 2X7DA 3K3BA 1MNEA 4GKRA 4E7SA 4ETPA 4LNUK 2ZFMA 1FMWA 2OWMA 3KENA 3BFNA 1VFWA 2X7CA 2XT3A 5LT1A 1F9TA 1BR4A 1V8JA 1VFZA 4PJNA 1BR1A 2FL2A 3WRDA 3T0QA 1D1AA 2ZFLA 1BR2A 2VB6A 4E7ZA 1D0YA 1MMGA 2V26A 1MMNA 3L9HA 4A1ZA 4BN2A 4PFPA 2UYIA 3KINA 4AP0A 1I6IA 2Q2ZA 1MMDA 3KARA 4H1GA 4A50A 2ZFIA 2FL6A 1I5SA 1RY6A 1GOJA 3ZCWA 2FKYA 3CJOA 2KINA 2ZFJA 4FRZA 1F9WA 2X2RA 3GBJA 3DC4A 3DCBA 2FMEA 2VASA 1F9VA 4DBRA 4ZHIA 1F9UA 3LREA 4DBQA 4Y05A 3ZFCA 1MKJA 1II6A 3NWNA 1VOMA 4B7BA 2Y5WA 2GRYA 1D1CA 4PJJA 1MMAA 3COBA 1YRSA 1G8XA 1X88A 4PJLA 3WPNA 1Q0BA 1T5CA 2Q2YA 5LT0A 4UBFA 4A28A 3L1CA 1D0ZA 5GSZA 3ZFDA 1N6MA 2UYMA 5LT3A 3H4SA 4BXNA 2VVGA 1CZ7A 1FMVA 2X51A 4BBGA 1SDMA 2G1QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HLE A;  2GM1 A;  4A51 A;  2HEH A;  1D1B A;  1LKX A;  2XAE A;  3B6V A;  4AS7 A;  2MYS A;  1LVK A;  1KK7 A;  2IEH A;  1V8K A;  3U06 A;  4PJM A;  4ZCA A;  3K5E A;  4A5Y A;  3B6U A;  3CNZ A;  5LT4 A;  2WOG A;  4HNA K;  4ANJ A;  1VFV A;  2ZFK A;  2NCD A;  3PXN A;  2PG2 A;  4PK4 A;  3HQD A;  2Y65 A;  2X7E A;  3X2T A;  1D0X A;  1VFX A;  4PFO A;  5LT2 A;  1BG2 A;  4A14 A;  2X7D A;  3K3B A;  1MNE A;  4GKR A;  4E7S A;  4ETP A;  4LNU K;  2ZFM A;  1FMW A;  2OWM A;  3KEN A;  3BFN A;  1VFW A;  2X7C A;  2XT3 A;  5LT1 A;  1F9T A;  1BR4 A;  1V8J A;  1VFZ A;  4PJN A;  1BR1 A;  2FL2 A;  3WRD A;  3T0Q A;  1D1A A;  2ZFL A;  1BR2 A;  2VB6 A;  4E7Z A;  1D0Y A;  1MMG A;  2V26 A;  1MMN A;  3L9H A;  4A1Z A;  4BN2 A;  4PFP A;  2UYI A;  3KIN A;  4AP0 A;  1I6I A;  2Q2Z A;  1MMD A;  3KAR A;  4H1G A;  4A50 A;  2ZFI A;  2FL6 A;  1I5S A;  1RY6 A;  1GOJ A;  3ZCW A;  2FKY A;  3CJO A;  2KIN A;  2ZFJ A;  4FRZ A;  1F9W A;  2X2R A;  3GBJ A;  3DC4 A;  3DCB A;  2FME A;  2VAS A;  1F9V A;  4DBR A;  4ZHI A;  1F9U A;  3LRE A;  4DBQ A;  4Y05 A;  3ZFC A;  1MKJ A;  1II6 A;  3NWN A;  1VOM A;  4B7B A;  2Y5W A;  2GRY A;  1D1C A;  4PJJ A;  1MMA A;  3COB A;  1YRS A;  1G8X A;  1X88 A;  4PJL A;  3WPN A;  1Q0B A;  1T5C A;  2Q2Y A;  5LT0 A;  4UBF A;  4A28 A;  3L1C A;  1D0Z A;  5GSZ A;  3ZFD A;  1N6M A;  2UYM A;  5LT3 A;  3H4S A;  4BXN A;  2VVG A;  1CZ7 A;  1FMV A;  2X51 A;  4BBG A;  1SDM A;  2G1Q A; 
#chains in the Genus database with same CATH topology
 5HLE A;  2O0A A;  2GM1 A;  4A51 A;  2HEH A;  1D1B A;  1LKX A;  2XAE A;  3B6V A;  4AS7 A;  2MYS A;  1LVK A;  1KK7 A;  2IEH A;  1V8K A;  3U06 A;  4PJM A;  4ZCA A;  3K5E A;  4A5Y A;  3B6U A;  3CNZ A;  5LT4 A;  2WOG A;  4HNA K;  4ANJ A;  1VFV A;  2ZFK A;  2NCD A;  3PXN A;  2PG2 A;  4PK4 A;  3HQD A;  2Y65 A;  2X7E A;  3X2T A;  1D0X A;  1VFX A;  4PFO A;  5LT2 A;  1BG2 A;  4A14 A;  2X7D A;  3K3B A;  1MNE A;  4GKR A;  4E7S A;  4ETP A;  4LNU K;  2ZFM A;  1FMW A;  2OWM A;  3KEN A;  3BFN A;  1VFW A;  2X7C A;  2XT3 A;  5LT1 A;  1F9T A;  1BR4 A;  1V8J A;  1VFZ A;  4PJN A;  1BR1 A;  2FL2 A;  4ETP B;  3WRD A;  3T0Q A;  1D1A A;  2ZFL A;  1BR2 A;  2VB6 A;  4E7Z A;  1D0Y A;  1MMG A;  2V26 A;  1MMN A;  3L9H A;  4A1Z A;  4BN2 A;  4PFP A;  2UYI A;  3KIN A;  4GKP A;  4AP0 A;  1I6I A;  2Q2Z A;  1MMD A;  3KAR A;  4H1G A;  4A50 A;  2ZFI A;  2FL6 A;  1I5S A;  1RY6 A;  1GOJ A;  3ZCW A;  2FKY A;  3CJO A;  2KIN A;  2ZFJ A;  4FRZ A;  1F9W A;  2X2R A;  3GBJ A;  3DC4 A;  3DCB A;  2FME A;  2VAS A;  1F9V A;  4DBR A;  4ZHI A;  1F9U A;  3LRE A;  4DBQ A;  4Y05 A;  3ZFC A;  1MKJ A;  1II6 A;  3NWN A;  1VOM A;  4B7B A;  2Y5W A;  2GRY A;  1D1C A;  4PJJ A;  1MMA A;  3COB A;  1YRS A;  1G8X A;  1X88 A;  4PJL A;  3WPN A;  1Q0B A;  1T5C A;  2Q2Y A;  5LT0 A;  4UBF A;  4A28 A;  3L1C A;  1D0Z A;  5GSZ A;  3ZFD A;  1N6M A;  2UYM A;  5LT3 A;  3H4S A;  4BXN A;  2VVG A;  1CZ7 A;  1FMV A;  4GKQ A;  2X51 A;  4BBG A;  1SDM A;  2G1Q A; 
#chains in the Genus database with same CATH homology
 5HLE A;  2GM1 A;  4A51 A;  2HEH A;  1D1B A;  1LKX A;  2XAE A;  3B6V A;  4AS7 A;  2MYS A;  1LVK A;  1KK7 A;  2IEH A;  1V8K A;  3U06 A;  4PJM A;  4ZCA A;  3K5E A;  4A5Y A;  3B6U A;  3CNZ A;  5LT4 A;  2WOG A;  4HNA K;  4ANJ A;  1VFV A;  2ZFK A;  2NCD A;  3PXN A;  2PG2 A;  4PK4 A;  3HQD A;  2Y65 A;  2X7E A;  3X2T A;  1D0X A;  1VFX A;  4PFO A;  5LT2 A;  1BG2 A;  4A14 A;  2X7D A;  3K3B A;  1MNE A;  4GKR A;  4E7S A;  4ETP A;  4LNU K;  2ZFM A;  1FMW A;  2OWM A;  3KEN A;  3BFN A;  1VFW A;  2X7C A;  2XT3 A;  5LT1 A;  1F9T A;  1BR4 A;  1V8J A;  1VFZ A;  4PJN A;  1BR1 A;  2FL2 A;  3WRD A;  3T0Q A;  1D1A A;  2ZFL A;  1BR2 A;  2VB6 A;  4E7Z A;  1D0Y A;  1MMG A;  2V26 A;  1MMN A;  3L9H A;  4A1Z A;  4BN2 A;  4PFP A;  2UYI A;  3KIN A;  4AP0 A;  1I6I A;  2Q2Z A;  1MMD A;  3KAR A;  4H1G A;  4A50 A;  2ZFI A;  2FL6 A;  1I5S A;  1RY6 A;  1GOJ A;  3ZCW A;  2FKY A;  3CJO A;  2KIN A;  2ZFJ A;  4FRZ A;  1F9W A;  2X2R A;  3GBJ A;  3DC4 A;  3DCB A;  2FME A;  2VAS A;  1F9V A;  4DBR A;  4ZHI A;  1F9U A;  3LRE A;  4DBQ A;  4Y05 A;  3ZFC A;  1MKJ A;  1II6 A;  3NWN A;  1VOM A;  4B7B A;  2Y5W A;  2GRY A;  1D1C A;  4PJJ A;  1MMA A;  3COB A;  1YRS A;  1G8X A;  1X88 A;  4PJL A;  3WPN A;  1Q0B A;  1T5C A;  2Q2Y A;  5LT0 A;  4UBF A;  4A28 A;  3L1C A;  1D0Z A;  5GSZ A;  3ZFD A;  1N6M A;  2UYM A;  5LT3 A;  3H4S A;  4BXN A;  2VVG A;  1CZ7 A;  1FMV A;  2X51 A;  4BBG A;  1SDM A;  2G1Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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