2Y65A

Crystal structure of drosophila melanogaster kinesin-1 motor domain dimer-tail complex
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
344
structure length
328
Chain Sequence
b'PAEDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIAGKVYLFDKVFKPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDIFNHIYAMEVNLEFHIKVSYYEIYMDKIRDLLDVSKVNLSVHEDKNRVPYVKGATERFVSSPEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLINVKQENLENQKKLSGKLYLVDLAGSEKINKSLSALGNVISALADGNKTHIPYRDSKLTRILQESLGGNARTTIVICCSPASFNESETKSTLDFGRRAKTVKNVVCVNEELTAEEWKRR'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords KINESIN HEAVY CHAIN
publication title The Structure of the Kinesin-1 Motor-Tail Complex Reveals the Mechanism of Autoinhibition.
pubmed doi rcsb
source organism Drosophila melanogaster
molecule tags Motor protein
total genus 108
structure length 328
sequence length 344
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2011-01-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 2y65A00
1D1BA 1SDMA 4ZHIA 4BBGA 4A5YA 2KINA 4LNUK 5GSZA 2Y5WA 2ZFLA 1KK7A 4DBRA 4HNAK 3H4SA 2X7EA 5LT3A 3GBJA 5HLEA 3KENA 3CNZA 2ZFKA 4E7ZA 1BR2A 3T0QA 1YRSA 2Q2ZA 4GKRA 2ZFIA 2WOGA 1F9TA 2X51A 3DCBA 1X88A 3LREA 1D1CA 1RY6A 1V8JA 4PJMA 4PJNA 3HQDA 4AP0A 2VVGA 2PG2A 3DC4A 5LT4A 2X7CA 2FL2A 1Q0BA 1D0ZA 1MKJA 1CZ7A 3CJOA 1I6IA 2GRYA 2G1QA 1D0YA 1MMDA 1VFVA 2NCDA 1G8XA 1F9UA 3COBA 3KARA 1D1AA 2FL6A 4UBFA 4E7SA 4AS7A 4B7BA 1MNEA 4FRZA 1LVKA 4PK4A 1V8KA 4A1ZA 1LKXA 4ANJA 3L9HA 2ZFMA 4ETPA 3ZFCA 4PJLA 1F9WA 1F9VA 2HEHA 1BG2A 2MYSA 4PFPA 3BFNA 1GOJA 2UYMA 2VB6A 3K5EA 3L1CA 1FMVA 5LT2A 2XT3A 1VFWA 1VFZA 4A50A 2XAEA 1MMNA 2Q2YA 1II6A 2VASA 3WPNA 3X2TA 1BR4A 1N6MA 3B6VA 3ZCWA 4A14A 4BXNA 2V26A 4A28A 4DBQA 1BR1A 1VFXA 2OWMA 1MMAA 3NWNA 5LT0A 2Y65A 1I5SA 1FMWA 4H1GA 2FKYA 3B6UA 1T5CA 2IEHA 2GM1A 2ZFJA 3WRDA 1MMGA 2FMEA 3U06A 2X7DA 2X2RA 5LT1A 4ZCAA 4BN2A 3KINA 4Y05A 3ZFDA 2UYIA 3K3BA 3PXNA 1VOMA 1D0XA 4PFOA 4PJJA 4A51A
chains in the Genus database with same CATH superfamily
1D1BA 1SDMA 4ZHIA 4BBGA 4A5YA 2KINA 4LNUK 5GSZA 2Y5WA 2ZFLA 1KK7A 4DBRA 4HNAK 3H4SA 2X7EA 5LT3A 3GBJA 5HLEA 3KENA 3CNZA 2ZFKA 4E7ZA 1BR2A 3T0QA 1YRSA 2Q2ZA 4GKRA 2ZFIA 2WOGA 1F9TA 2X51A 3DCBA 1X88A 3LREA 1D1CA 1RY6A 1V8JA 4PJMA 4PJNA 3HQDA 4AP0A 2VVGA 2PG2A 3DC4A 5LT4A 2X7CA 4ETPB 2FL2A 1Q0BA 1D0ZA 1MKJA 1CZ7A 3CJOA 4GKQA 4GKPA 1I6IA 2GRYA 2G1QA 1D0YA 1MMDA 1VFVA 2O0AA 2NCDA 1G8XA 1F9UA 3COBA 3KARA 1D1AA 2FL6A 4UBFA 4E7SA 4AS7A 4B7BA 1MNEA 4FRZA 1LVKA 4PK4A 1V8KA 4A1ZA 1LKXA 4ANJA 3L9HA 2ZFMA 4ETPA 3ZFCA 4PJLA 1F9WA 1F9VA 2HEHA 1BG2A 2MYSA 4PFPA 3BFNA 1GOJA 2UYMA 2VB6A 3K5EA 3L1CA 1FMVA 5LT2A 2XT3A 1VFWA 1VFZA 4A50A 2XAEA 1MMNA 2Q2YA 1II6A 2VASA 3WPNA 3X2TA 1BR4A 1N6MA 3B6VA 3ZCWA 4A14A 4BXNA 2V26A 4A28A 4DBQA 1BR1A 1VFXA 2OWMA 1MMAA 3NWNA 5LT0A 2Y65A 1I5SA 1FMWA 4H1GA 2FKYA 3B6UA 1T5CA 2IEHA 2GM1A 2ZFJA 3WRDA 1MMGA 2FMEA 3U06A 2X7DA 2X2RA 5LT1A 4ZCAA 4BN2A 3KINA 4Y05A 3ZFDA 2UYIA 3K3BA 3PXNA 1VOMA 1D0XA 4PFOA 4PJJA 4A51A
chains in the Genus database with same CATH topology
1D1BA 1SDMA 4ZHIA 4BBGA 4A5YA 2KINA 4LNUK 5GSZA 2Y5WA 2ZFLA 1KK7A 4DBRA 4HNAK 3H4SA 2X7EA 5LT3A 3GBJA 5HLEA 3KENA 3CNZA 2ZFKA 4E7ZA 1BR2A 3T0QA 1YRSA 2Q2ZA 4GKRA 2ZFIA 2WOGA 1F9TA 2X51A 3DCBA 1X88A 3LREA 1D1CA 1RY6A 1V8JA 4PJMA 4PJNA 3HQDA 4AP0A 2VVGA 2PG2A 3DC4A 5LT4A 2X7CA 2FL2A 1Q0BA 1D0ZA 1MKJA 1CZ7A 3CJOA 1I6IA 2GRYA 2G1QA 1D0YA 1MMDA 1VFVA 2NCDA 1G8XA 1F9UA 3COBA 3KARA 1D1AA 2FL6A 4UBFA 4E7SA 4AS7A 4B7BA 1MNEA 4FRZA 1LVKA 4PK4A 1V8KA 4A1ZA 1LKXA 4ANJA 3L9HA 2ZFMA 4ETPA 3ZFCA 4PJLA 1F9WA 1F9VA 2HEHA 1BG2A 2MYSA 4PFPA 3BFNA 1GOJA 2UYMA 2VB6A 3K5EA 3L1CA 1FMVA 5LT2A 2XT3A 1VFWA 1VFZA 4A50A 2XAEA 1MMNA 2Q2YA 1II6A 2VASA 3WPNA 3X2TA 1BR4A 1N6MA 3B6VA 3ZCWA 4A14A 4BXNA 2V26A 4A28A 4DBQA 1BR1A 1VFXA 2OWMA 1MMAA 3NWNA 5LT0A 2Y65A 1I5SA 1FMWA 4H1GA 2FKYA 3B6UA 1T5CA 2IEHA 2GM1A 2ZFJA 3WRDA 1MMGA 2FMEA 3U06A 2X7DA 2X2RA 5LT1A 4ZCAA 4BN2A 3KINA 4Y05A 3ZFDA 2UYIA 3K3BA 3PXNA 1VOMA 1D0XA 4PFOA 4PJJA 4A51A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1D1B A;  1SDM A;  4ZHI A;  4BBG A;  4A5Y A;  2KIN A;  4LNU K;  5GSZ A;  2Y5W A;  2ZFL A;  1KK7 A;  4DBR A;  4HNA K;  3H4S A;  2X7E A;  5LT3 A;  3GBJ A;  5HLE A;  3KEN A;  3CNZ A;  2ZFK A;  4E7Z A;  1BR2 A;  3T0Q A;  1YRS A;  2Q2Z A;  4GKR A;  2ZFI A;  2WOG A;  1F9T A;  2X51 A;  3DCB A;  1X88 A;  3LRE A;  1D1C A;  1RY6 A;  1V8J A;  4PJM A;  4PJN A;  3HQD A;  4AP0 A;  2VVG A;  2PG2 A;  3DC4 A;  5LT4 A;  2X7C A;  2FL2 A;  1Q0B A;  1D0Z A;  1MKJ A;  1CZ7 A;  3CJO A;  1I6I A;  2GRY A;  2G1Q A;  1D0Y A;  1MMD A;  1VFV A;  2NCD A;  1G8X A;  1F9U A;  3COB A;  3KAR A;  1D1A A;  2FL6 A;  4UBF A;  4E7S A;  4AS7 A;  4B7B A;  1MNE A;  4FRZ A;  1LVK A;  4PK4 A;  1V8K A;  4A1Z A;  1LKX A;  4ANJ A;  3L9H A;  2ZFM A;  4ETP A;  3ZFC A;  4PJL A;  1F9W A;  1F9V A;  2HEH A;  1BG2 A;  2MYS A;  4PFP A;  3BFN A;  1GOJ A;  2UYM A;  2VB6 A;  3K5E A;  3L1C A;  1FMV A;  5LT2 A;  2XT3 A;  1VFW A;  1VFZ A;  4A50 A;  2XAE A;  1MMN A;  2Q2Y A;  1II6 A;  2VAS A;  3WPN A;  3X2T A;  1BR4 A;  1N6M A;  3B6V A;  3ZCW A;  4A14 A;  4BXN A;  2V26 A;  4A28 A;  4DBQ A;  1BR1 A;  1VFX A;  2OWM A;  1MMA A;  3NWN A;  5LT0 A;  2Y65 A;  1I5S A;  1FMW A;  4H1G A;  2FKY A;  3B6U A;  1T5C A;  2IEH A;  2GM1 A;  2ZFJ A;  3WRD A;  1MMG A;  2FME A;  3U06 A;  2X7D A;  2X2R A;  5LT1 A;  4ZCA A;  4BN2 A;  3KIN A;  4Y05 A;  3ZFD A;  2UYI A;  3K3B A;  3PXN A;  1VOM A;  1D0X A;  4PFO A;  4PJJ A;  4A51 A; 
#chains in the Genus database with same CATH topology
 1D1B A;  1SDM A;  4ZHI A;  4BBG A;  4A5Y A;  2KIN A;  4LNU K;  5GSZ A;  2Y5W A;  2ZFL A;  1KK7 A;  4DBR A;  4HNA K;  3H4S A;  2X7E A;  5LT3 A;  3GBJ A;  5HLE A;  3KEN A;  3CNZ A;  2ZFK A;  4E7Z A;  1BR2 A;  3T0Q A;  1YRS A;  2Q2Z A;  4GKR A;  2ZFI A;  2WOG A;  1F9T A;  2X51 A;  3DCB A;  1X88 A;  3LRE A;  1D1C A;  1RY6 A;  1V8J A;  4PJM A;  4PJN A;  3HQD A;  4AP0 A;  2VVG A;  2PG2 A;  3DC4 A;  5LT4 A;  2X7C A;  4ETP B;  2FL2 A;  1Q0B A;  1D0Z A;  1MKJ A;  1CZ7 A;  3CJO A;  4GKQ A;  4GKP A;  1I6I A;  2GRY A;  2G1Q A;  1D0Y A;  1MMD A;  1VFV A;  2O0A A;  2NCD A;  1G8X A;  1F9U A;  3COB A;  3KAR A;  1D1A A;  2FL6 A;  4UBF A;  4E7S A;  4AS7 A;  4B7B A;  1MNE A;  4FRZ A;  1LVK A;  4PK4 A;  1V8K A;  4A1Z A;  1LKX A;  4ANJ A;  3L9H A;  2ZFM A;  4ETP A;  3ZFC A;  4PJL A;  1F9W A;  1F9V A;  2HEH A;  1BG2 A;  2MYS A;  4PFP A;  3BFN A;  1GOJ A;  2UYM A;  2VB6 A;  3K5E A;  3L1C A;  1FMV A;  5LT2 A;  2XT3 A;  1VFW A;  1VFZ A;  4A50 A;  2XAE A;  1MMN A;  2Q2Y A;  1II6 A;  2VAS A;  3WPN A;  3X2T A;  1BR4 A;  1N6M A;  3B6V A;  3ZCW A;  4A14 A;  4BXN A;  2V26 A;  4A28 A;  4DBQ A;  1BR1 A;  1VFX A;  2OWM A;  1MMA A;  3NWN A;  5LT0 A;  2Y65 A;  1I5S A;  1FMW A;  4H1G A;  2FKY A;  3B6U A;  1T5C A;  2IEH A;  2GM1 A;  2ZFJ A;  3WRD A;  1MMG A;  2FME A;  3U06 A;  2X7D A;  2X2R A;  5LT1 A;  4ZCA A;  4BN2 A;  3KIN A;  4Y05 A;  3ZFD A;  2UYI A;  3K3B A;  3PXN A;  1VOM A;  1D0X A;  4PFO A;  4PJJ A;  4A51 A; 
#chains in the Genus database with same CATH homology
 1D1B A;  1SDM A;  4ZHI A;  4BBG A;  4A5Y A;  2KIN A;  4LNU K;  5GSZ A;  2Y5W A;  2ZFL A;  1KK7 A;  4DBR A;  4HNA K;  3H4S A;  2X7E A;  5LT3 A;  3GBJ A;  5HLE A;  3KEN A;  3CNZ A;  2ZFK A;  4E7Z A;  1BR2 A;  3T0Q A;  1YRS A;  2Q2Z A;  4GKR A;  2ZFI A;  2WOG A;  1F9T A;  2X51 A;  3DCB A;  1X88 A;  3LRE A;  1D1C A;  1RY6 A;  1V8J A;  4PJM A;  4PJN A;  3HQD A;  4AP0 A;  2VVG A;  2PG2 A;  3DC4 A;  5LT4 A;  2X7C A;  2FL2 A;  1Q0B A;  1D0Z A;  1MKJ A;  1CZ7 A;  3CJO A;  1I6I A;  2GRY A;  2G1Q A;  1D0Y A;  1MMD A;  1VFV A;  2NCD A;  1G8X A;  1F9U A;  3COB A;  3KAR A;  1D1A A;  2FL6 A;  4UBF A;  4E7S A;  4AS7 A;  4B7B A;  1MNE A;  4FRZ A;  1LVK A;  4PK4 A;  1V8K A;  4A1Z A;  1LKX A;  4ANJ A;  3L9H A;  2ZFM A;  4ETP A;  3ZFC A;  4PJL A;  1F9W A;  1F9V A;  2HEH A;  1BG2 A;  2MYS A;  4PFP A;  3BFN A;  1GOJ A;  2UYM A;  2VB6 A;  3K5E A;  3L1C A;  1FMV A;  5LT2 A;  2XT3 A;  1VFW A;  1VFZ A;  4A50 A;  2XAE A;  1MMN A;  2Q2Y A;  1II6 A;  2VAS A;  3WPN A;  3X2T A;  1BR4 A;  1N6M A;  3B6V A;  3ZCW A;  4A14 A;  4BXN A;  2V26 A;  4A28 A;  4DBQ A;  1BR1 A;  1VFX A;  2OWM A;  1MMA A;  3NWN A;  5LT0 A;  2Y65 A;  1I5S A;  1FMW A;  4H1G A;  2FKY A;  3B6U A;  1T5C A;  2IEH A;  2GM1 A;  2ZFJ A;  3WRD A;  1MMG A;  2FME A;  3U06 A;  2X7D A;  2X2R A;  5LT1 A;  4ZCA A;  4BN2 A;  3KIN A;  4Y05 A;  3ZFD A;  2UYI A;  3K3B A;  3PXN A;  1VOM A;  1D0X A;  4PFO A;  4PJJ A;  4A51 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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