2Y65A

Crystal structure of drosophila melanogaster kinesin-1 motor domain dimer-tail complex
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
344
structure length
328
Chain Sequence
PAEDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIAGKVYLFDKVFKPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDIFNHIYAMEVNLEFHIKVSYYEIYMDKIRDLLDVSKVNLSVHEDKNRVPYVKGATERFVSSPEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLINVKQENLENQKKLSGKLYLVDLAGSEKINKSLSALGNVISALADGNKTHIPYRDSKLTRILQESLGGNARTTIVICCSPASFNESETKSTLDFGRRAKTVKNVVCVNEELTAEEWKRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the Kinesin-1 Motor-Tail Complex Reveals the Mechanism of Autoinhibition.
pubmed doi rcsb
molecule tags Motor protein
source organism Drosophila melanogaster
molecule keywords KINESIN HEAVY CHAIN
total genus 108
structure length 328
sequence length 344
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2011-01-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 2y65A00
4PJNA 1Q0BA 2X7DA 2ZFIA 1YRSA 2Q2YA 3H4SA 4ZCAA 5LT2A 2Y5WA 4PJLA 1F9VA 3DC4A 2Q2ZA 4ETPA 4PJJA 3LREA 3ZFCA 5HLEA 4DBQA 4DBRA 3B6VA 2ZFKA 2VVGA 4AP0A 4BBGA 4FRZA 1F9TA 1V8KA 2ZFJA 3ZCWA 1BR2A 1SDMA 2VB6A 1I6IA 4ZHIA 2ZFMA 3B6UA 4E7SA 1BG2A 1D0ZA 1F9WA 3X2TA 3CNZA 3WRDA 1BR1A 2ZFLA 3T0QA 1G8XA 1N6MA 5LT3A 2IEHA 5LT0A 1V8JA 2HEHA 2NCDA 1VFVA 2X2RA 4BXNA 1D0YA 1KK7A 1MMDA 2XAEA 2X51A 4A14A 1FMVA 3GBJA 1VFWA 2GRYA 3K5EA 2FMEA 2X7EA 3L9HA 4GKRA 1VFXA 4A51A 2V26A 3BFNA 1VOMA 3L1CA 2OWMA 1CZ7A 3KINA 3U06A 2MYSA 2WOGA 4A50A 1X88A 2XT3A 5LT4A 1MMNA 1RY6A 2KINA 3KARA 4PFOA 3NWNA 4PFPA 4LNUK 4Y05A 1II6A 1MKJA 4BN2A 1D0XA 1D1AA 4E7ZA 2UYIA 1MMGA 1D1CA 3DCBA 4A5YA 3K3BA 1MMAA 4PK4A 4A1ZA 1LKXA 1F9UA 3ZFDA 1GOJA 2GM1A 4ANJA 2VASA 1T5CA 3HQDA 2X7CA 2PG2A 2UYMA 3KENA 4B7BA 4H1GA 2FL6A 2Y65A 1VFZA 3CJOA 4HNAK 5LT1A 2G1QA 2FL2A 1LVKA 4AS7A 1FMWA 5GSZA 1D1BA 2FKYA 3COBA 1MNEA 4A28A 4PJMA 1I5SA 4UBFA 3WPNA 3PXNA 1BR4A
chains in the Genus database with same CATH superfamily
4PJNA 1Q0BA 2X7DA 2ZFIA 1YRSA 2Q2YA 3H4SA 4ZCAA 5LT2A 2Y5WA 4PJLA 1F9VA 3DC4A 2Q2ZA 4ETPA 4PJJA 3LREA 3ZFCA 5HLEA 4DBQA 4DBRA 3B6VA 2ZFKA 2VVGA 4AP0A 4BBGA 4FRZA 1F9TA 1V8KA 2ZFJA 3ZCWA 1BR2A 1SDMA 2VB6A 1I6IA 4ZHIA 2ZFMA 3B6UA 4E7SA 1BG2A 1D0ZA 1F9WA 3X2TA 3CNZA 3WRDA 1BR1A 2ZFLA 3T0QA 1G8XA 1N6MA 5LT3A 2IEHA 5LT0A 1V8JA 2HEHA 2NCDA 1VFVA 2X2RA 4GKPA 4BXNA 1D0YA 1KK7A 1MMDA 2XAEA 2X51A 4A14A 1FMVA 3GBJA 1VFWA 2GRYA 3K5EA 2FMEA 2X7EA 3L9HA 4GKRA 1VFXA 4A51A 2V26A 3BFNA 1VOMA 3L1CA 2O0AA 2OWMA 1CZ7A 3KINA 3U06A 2MYSA 2WOGA 4A50A 1X88A 2XT3A 5LT4A 1MMNA 1RY6A 2KINA 3KARA 4PFOA 3NWNA 4PFPA 4LNUK 4Y05A 1II6A 1MKJA 4BN2A 1D0XA 1D1AA 4GKQA 4E7ZA 2UYIA 1MMGA 1D1CA 3DCBA 4A5YA 3K3BA 1MMAA 4PK4A 4A1ZA 1LKXA 1F9UA 3ZFDA 1GOJA 2GM1A 4ANJA 4ETPB 2VASA 1T5CA 3HQDA 2X7CA 2PG2A 2UYMA 3KENA 4B7BA 4H1GA 2FL6A 2Y65A 1VFZA 3CJOA 4HNAK 5LT1A 2G1QA 2FL2A 1LVKA 4AS7A 1FMWA 5GSZA 1D1BA 2FKYA 3COBA 1MNEA 4A28A 4PJMA 1I5SA 4UBFA 3WPNA 3PXNA 1BR4A
chains in the Genus database with same CATH topology
4PJNA 1Q0BA 2X7DA 2ZFIA 1YRSA 2Q2YA 3H4SA 4ZCAA 5LT2A 2Y5WA 4PJLA 1F9VA 3DC4A 2Q2ZA 4ETPA 4PJJA 3LREA 3ZFCA 5HLEA 4DBQA 4DBRA 3B6VA 2ZFKA 2VVGA 4AP0A 4BBGA 4FRZA 1F9TA 1V8KA 2ZFJA 3ZCWA 1BR2A 1SDMA 2VB6A 1I6IA 4ZHIA 2ZFMA 3B6UA 4E7SA 1BG2A 1D0ZA 1F9WA 3X2TA 3CNZA 3WRDA 1BR1A 2ZFLA 3T0QA 1G8XA 1N6MA 5LT3A 2IEHA 5LT0A 1V8JA 2HEHA 2NCDA 1VFVA 2X2RA 4BXNA 1D0YA 1KK7A 1MMDA 2XAEA 2X51A 4A14A 1FMVA 3GBJA 1VFWA 2GRYA 3K5EA 2FMEA 2X7EA 3L9HA 4GKRA 1VFXA 4A51A 2V26A 3BFNA 1VOMA 3L1CA 2OWMA 1CZ7A 3KINA 3U06A 2MYSA 2WOGA 4A50A 1X88A 2XT3A 5LT4A 1MMNA 1RY6A 2KINA 3KARA 4PFOA 3NWNA 4PFPA 4LNUK 4Y05A 1II6A 1MKJA 4BN2A 1D0XA 1D1AA 4E7ZA 2UYIA 1MMGA 1D1CA 3DCBA 4A5YA 3K3BA 1MMAA 4PK4A 4A1ZA 1LKXA 1F9UA 3ZFDA 1GOJA 2GM1A 4ANJA 2VASA 1T5CA 3HQDA 2X7CA 2PG2A 2UYMA 3KENA 4B7BA 4H1GA 2FL6A 2Y65A 1VFZA 3CJOA 4HNAK 5LT1A 2G1QA 2FL2A 1LVKA 4AS7A 1FMWA 5GSZA 1D1BA 2FKYA 3COBA 1MNEA 4A28A 4PJMA 1I5SA 4UBFA 3WPNA 3PXNA 1BR4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PJN A;  1Q0B A;  2X7D A;  2ZFI A;  1YRS A;  2Q2Y A;  3H4S A;  4ZCA A;  5LT2 A;  2Y5W A;  4PJL A;  1F9V A;  3DC4 A;  2Q2Z A;  4ETP A;  4PJJ A;  3LRE A;  3ZFC A;  5HLE A;  4DBQ A;  4DBR A;  3B6V A;  2ZFK A;  2VVG A;  4AP0 A;  4BBG A;  4FRZ A;  1F9T A;  1V8K A;  2ZFJ A;  3ZCW A;  1BR2 A;  1SDM A;  2VB6 A;  1I6I A;  4ZHI A;  2ZFM A;  3B6U A;  4E7S A;  1BG2 A;  1D0Z A;  1F9W A;  3X2T A;  3CNZ A;  3WRD A;  1BR1 A;  2ZFL A;  3T0Q A;  1G8X A;  1N6M A;  5LT3 A;  2IEH A;  5LT0 A;  1V8J A;  2HEH A;  2NCD A;  1VFV A;  2X2R A;  4BXN A;  1D0Y A;  1KK7 A;  1MMD A;  2XAE A;  2X51 A;  4A14 A;  1FMV A;  3GBJ A;  1VFW A;  2GRY A;  3K5E A;  2FME A;  2X7E A;  3L9H A;  4GKR A;  1VFX A;  4A51 A;  2V26 A;  3BFN A;  1VOM A;  3L1C A;  2OWM A;  1CZ7 A;  3KIN A;  3U06 A;  2MYS A;  2WOG A;  4A50 A;  1X88 A;  2XT3 A;  5LT4 A;  1MMN A;  1RY6 A;  2KIN A;  3KAR A;  4PFO A;  3NWN A;  4PFP A;  4LNU K;  4Y05 A;  1II6 A;  1MKJ A;  4BN2 A;  1D0X A;  1D1A A;  4E7Z A;  2UYI A;  1MMG A;  1D1C A;  3DCB A;  4A5Y A;  3K3B A;  1MMA A;  4PK4 A;  4A1Z A;  1LKX A;  1F9U A;  3ZFD A;  1GOJ A;  2GM1 A;  4ANJ A;  2VAS A;  1T5C A;  3HQD A;  2X7C A;  2PG2 A;  2UYM A;  3KEN A;  4B7B A;  4H1G A;  2FL6 A;  2Y65 A;  1VFZ A;  3CJO A;  4HNA K;  5LT1 A;  2G1Q A;  2FL2 A;  1LVK A;  4AS7 A;  1FMW A;  5GSZ A;  1D1B A;  2FKY A;  3COB A;  1MNE A;  4A28 A;  4PJM A;  1I5S A;  4UBF A;  3WPN A;  3PXN A;  1BR4 A; 
#chains in the Genus database with same CATH topology
 4PJN A;  1Q0B A;  2X7D A;  2ZFI A;  1YRS A;  2Q2Y A;  3H4S A;  4ZCA A;  5LT2 A;  2Y5W A;  4PJL A;  1F9V A;  3DC4 A;  2Q2Z A;  4ETP A;  4PJJ A;  3LRE A;  3ZFC A;  5HLE A;  4DBQ A;  4DBR A;  3B6V A;  2ZFK A;  2VVG A;  4AP0 A;  4BBG A;  4FRZ A;  1F9T A;  1V8K A;  2ZFJ A;  3ZCW A;  1BR2 A;  1SDM A;  2VB6 A;  1I6I A;  4ZHI A;  2ZFM A;  3B6U A;  4E7S A;  1BG2 A;  1D0Z A;  1F9W A;  3X2T A;  3CNZ A;  3WRD A;  1BR1 A;  2ZFL A;  3T0Q A;  1G8X A;  1N6M A;  5LT3 A;  2IEH A;  5LT0 A;  1V8J A;  2HEH A;  2NCD A;  1VFV A;  2X2R A;  4GKP A;  4BXN A;  1D0Y A;  1KK7 A;  1MMD A;  2XAE A;  2X51 A;  4A14 A;  1FMV A;  3GBJ A;  1VFW A;  2GRY A;  3K5E A;  2FME A;  2X7E A;  3L9H A;  4GKR A;  1VFX A;  4A51 A;  2V26 A;  3BFN A;  1VOM A;  3L1C A;  2O0A A;  2OWM A;  1CZ7 A;  3KIN A;  3U06 A;  2MYS A;  2WOG A;  4A50 A;  1X88 A;  2XT3 A;  5LT4 A;  1MMN A;  1RY6 A;  2KIN A;  3KAR A;  4PFO A;  3NWN A;  4PFP A;  4LNU K;  4Y05 A;  1II6 A;  1MKJ A;  4BN2 A;  1D0X A;  1D1A A;  4GKQ A;  4E7Z A;  2UYI A;  1MMG A;  1D1C A;  3DCB A;  4A5Y A;  3K3B A;  1MMA A;  4PK4 A;  4A1Z A;  1LKX A;  1F9U A;  3ZFD A;  1GOJ A;  2GM1 A;  4ANJ A;  4ETP B;  2VAS A;  1T5C A;  3HQD A;  2X7C A;  2PG2 A;  2UYM A;  3KEN A;  4B7B A;  4H1G A;  2FL6 A;  2Y65 A;  1VFZ A;  3CJO A;  4HNA K;  5LT1 A;  2G1Q A;  2FL2 A;  1LVK A;  4AS7 A;  1FMW A;  5GSZ A;  1D1B A;  2FKY A;  3COB A;  1MNE A;  4A28 A;  4PJM A;  1I5S A;  4UBF A;  3WPN A;  3PXN A;  1BR4 A; 
#chains in the Genus database with same CATH homology
 4PJN A;  1Q0B A;  2X7D A;  2ZFI A;  1YRS A;  2Q2Y A;  3H4S A;  4ZCA A;  5LT2 A;  2Y5W A;  4PJL A;  1F9V A;  3DC4 A;  2Q2Z A;  4ETP A;  4PJJ A;  3LRE A;  3ZFC A;  5HLE A;  4DBQ A;  4DBR A;  3B6V A;  2ZFK A;  2VVG A;  4AP0 A;  4BBG A;  4FRZ A;  1F9T A;  1V8K A;  2ZFJ A;  3ZCW A;  1BR2 A;  1SDM A;  2VB6 A;  1I6I A;  4ZHI A;  2ZFM A;  3B6U A;  4E7S A;  1BG2 A;  1D0Z A;  1F9W A;  3X2T A;  3CNZ A;  3WRD A;  1BR1 A;  2ZFL A;  3T0Q A;  1G8X A;  1N6M A;  5LT3 A;  2IEH A;  5LT0 A;  1V8J A;  2HEH A;  2NCD A;  1VFV A;  2X2R A;  4BXN A;  1D0Y A;  1KK7 A;  1MMD A;  2XAE A;  2X51 A;  4A14 A;  1FMV A;  3GBJ A;  1VFW A;  2GRY A;  3K5E A;  2FME A;  2X7E A;  3L9H A;  4GKR A;  1VFX A;  4A51 A;  2V26 A;  3BFN A;  1VOM A;  3L1C A;  2OWM A;  1CZ7 A;  3KIN A;  3U06 A;  2MYS A;  2WOG A;  4A50 A;  1X88 A;  2XT3 A;  5LT4 A;  1MMN A;  1RY6 A;  2KIN A;  3KAR A;  4PFO A;  3NWN A;  4PFP A;  4LNU K;  4Y05 A;  1II6 A;  1MKJ A;  4BN2 A;  1D0X A;  1D1A A;  4E7Z A;  2UYI A;  1MMG A;  1D1C A;  3DCB A;  4A5Y A;  3K3B A;  1MMA A;  4PK4 A;  4A1Z A;  1LKX A;  1F9U A;  3ZFD A;  1GOJ A;  2GM1 A;  4ANJ A;  2VAS A;  1T5C A;  3HQD A;  2X7C A;  2PG2 A;  2UYM A;  3KEN A;  4B7B A;  4H1G A;  2FL6 A;  2Y65 A;  1VFZ A;  3CJO A;  4HNA K;  5LT1 A;  2G1Q A;  2FL2 A;  1LVK A;  4AS7 A;  1FMW A;  5GSZ A;  1D1B A;  2FKY A;  3COB A;  1MNE A;  4A28 A;  4PJM A;  1I5S A;  4UBF A;  3WPN A;  3PXN A;  1BR4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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