4UBFA

Hsmcak motor domain complex
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
360
structure length
309
Chain Sequence
PNWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGKGIYAMASRDVFLLKGLEVYVTFFEIYNGKLFDLLNKKAKLRVLEVQVVGLQEHLVNSADDVIKMIDMGSACRRSHACFQIILRAKGRMHGKFSLVDLAGNEGAEINKSLLALKECIRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIATISPGISSCEYTLNTLRYADRVKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords Kinesin-like protein KIF2C
total genus 65
structure length 309
sequence length 360
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2014-08-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 4ubfA00
3CNZA 3WRDA 4A14A 1G8XA 4E7ZA 1X88A 3WPNA 3ZFDA 5LT2A 1MMNA 2ZFKA 1KK7A 2XAEA 5LT1A 1VFZA 2FL6A 1BR2A 1V8KA 1F9TA 1MKJA 3X2TA 4FRZA 4A5YA 1II6A 1MMGA 5LT3A 3COBA 1VFXA 1VFWA 4PJNA 4DBQA 2PG2A 1BR1A 2UYIA 2X7CA 2IEHA 4PJMA 1VOMA 1FMVA 3L1CA 4E7SA 4PJJA 2OWMA 3T0QA 4BXNA 4ZCAA 1D0YA 1CZ7A 2ZFIA 2Q2ZA 3KARA 1D0XA 2XT3A 2G1QA 4Y05A 4ZHIA 1MMDA 1V8JA 2NCDA 2Y65A 2V26A 2X7DA 4LNUK 3KENA 4GKRA 2HEHA 4PK4A 4UBFA 2GM1A 3K5EA 2Y5WA 4A50A 1GOJA 2MYSA 4HNAK 2GRYA 2UYMA 2VB6A 5HLEA 2X7EA 3NWNA 1VFVA 1LVKA 3HQDA 3L9HA 1MNEA 2VVGA 3KINA 4AS7A 1N6MA 2FL2A 3PXNA 2Q2YA 3U06A 3B6VA 3B6UA 4A51A 5LT0A 1FMWA 2ZFLA 3DC4A 4A1ZA 4BN2A 4B7BA 1LKXA 1BR4A 2ZFMA 3ZCWA 5LT4A 2KINA 1F9VA 3DCBA 1I5SA 4DBRA 2VASA 4PFOA 1F9UA 4H1GA 4A28A 1D0ZA 3ZFCA 1YRSA 2X51A 1D1CA 1T5CA 1F9WA 4PJLA 2X2RA 2FKYA 3K3BA 1MMAA 1RY6A 1BG2A 4AP0A 3GBJA 2ZFJA 3LREA 3BFNA 1I6IA 5GSZA 3H4SA 4ETPA 3CJOA 2FMEA 1D1AA 1D1BA 4PFPA 1Q0BA 1SDMA 4ANJA 4BBGA 2WOGA
chains in the Genus database with same CATH superfamily
3CNZA 3WRDA 4A14A 1G8XA 4E7ZA 1X88A 3WPNA 3ZFDA 5LT2A 1MMNA 2ZFKA 1KK7A 2XAEA 5LT1A 1VFZA 2FL6A 1BR2A 1V8KA 1F9TA 1MKJA 3X2TA 4FRZA 4GKPA 4A5YA 1II6A 1MMGA 5LT3A 3COBA 1VFXA 1VFWA 4PJNA 4DBQA 2PG2A 1BR1A 2UYIA 2X7CA 2IEHA 4PJMA 1VOMA 1FMVA 3L1CA 4E7SA 4PJJA 2OWMA 3T0QA 4BXNA 4ZCAA 1D0YA 1CZ7A 2O0AA 2ZFIA 2Q2ZA 3KARA 1D0XA 2XT3A 2G1QA 4Y05A 4ZHIA 1MMDA 1V8JA 2NCDA 2Y65A 2V26A 2X7DA 4LNUK 3KENA 4GKRA 2HEHA 4PK4A 4UBFA 2GM1A 3K5EA 2Y5WA 4A50A 1GOJA 2MYSA 4ETPB 4HNAK 2GRYA 2UYMA 2VB6A 5HLEA 2X7EA 3NWNA 1VFVA 1LVKA 3HQDA 3L9HA 1MNEA 2VVGA 3KINA 4AS7A 1N6MA 2FL2A 3PXNA 2Q2YA 3U06A 3B6VA 3B6UA 4A51A 5LT0A 1FMWA 2ZFLA 3DC4A 4A1ZA 4BN2A 4B7BA 1LKXA 1BR4A 2ZFMA 3ZCWA 5LT4A 2KINA 1F9VA 3DCBA 1I5SA 4DBRA 2VASA 4PFOA 1F9UA 4H1GA 4A28A 1D0ZA 3ZFCA 1YRSA 2X51A 1D1CA 1T5CA 1F9WA 4PJLA 2X2RA 2FKYA 3K3BA 1MMAA 1RY6A 4GKQA 1BG2A 4AP0A 3GBJA 2ZFJA 3LREA 3BFNA 1I6IA 5GSZA 3H4SA 4ETPA 3CJOA 2FMEA 1D1AA 1D1BA 4PFPA 1Q0BA 1SDMA 4ANJA 4BBGA 2WOGA
chains in the Genus database with same CATH topology
3CNZA 3WRDA 4A14A 1G8XA 4E7ZA 1X88A 3WPNA 3ZFDA 5LT2A 1MMNA 2ZFKA 1KK7A 2XAEA 5LT1A 1VFZA 2FL6A 1BR2A 1V8KA 1F9TA 1MKJA 3X2TA 4FRZA 4A5YA 1II6A 1MMGA 5LT3A 3COBA 1VFXA 1VFWA 4PJNA 4DBQA 2PG2A 1BR1A 2UYIA 2X7CA 2IEHA 4PJMA 1VOMA 1FMVA 3L1CA 4E7SA 4PJJA 2OWMA 3T0QA 4BXNA 4ZCAA 1D0YA 1CZ7A 2ZFIA 2Q2ZA 3KARA 1D0XA 2XT3A 2G1QA 4Y05A 4ZHIA 1MMDA 1V8JA 2NCDA 2Y65A 2V26A 2X7DA 4LNUK 3KENA 4GKRA 2HEHA 4PK4A 4UBFA 2GM1A 3K5EA 2Y5WA 4A50A 1GOJA 2MYSA 4HNAK 2GRYA 2UYMA 2VB6A 5HLEA 2X7EA 3NWNA 1VFVA 1LVKA 3HQDA 3L9HA 1MNEA 2VVGA 3KINA 4AS7A 1N6MA 2FL2A 3PXNA 2Q2YA 3U06A 3B6VA 3B6UA 4A51A 5LT0A 1FMWA 2ZFLA 3DC4A 4A1ZA 4BN2A 4B7BA 1LKXA 1BR4A 2ZFMA 3ZCWA 5LT4A 2KINA 1F9VA 3DCBA 1I5SA 4DBRA 2VASA 4PFOA 1F9UA 4H1GA 4A28A 1D0ZA 3ZFCA 1YRSA 2X51A 1D1CA 1T5CA 1F9WA 4PJLA 2X2RA 2FKYA 3K3BA 1MMAA 1RY6A 1BG2A 4AP0A 3GBJA 2ZFJA 3LREA 3BFNA 1I6IA 5GSZA 3H4SA 4ETPA 3CJOA 2FMEA 1D1AA 1D1BA 4PFPA 1Q0BA 1SDMA 4ANJA 4BBGA 2WOGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CNZ A;  3WRD A;  4A14 A;  1G8X A;  4E7Z A;  1X88 A;  3WPN A;  3ZFD A;  5LT2 A;  1MMN A;  2ZFK A;  1KK7 A;  2XAE A;  5LT1 A;  1VFZ A;  2FL6 A;  1BR2 A;  1V8K A;  1F9T A;  1MKJ A;  3X2T A;  4FRZ A;  4A5Y A;  1II6 A;  1MMG A;  5LT3 A;  3COB A;  1VFX A;  1VFW A;  4PJN A;  4DBQ A;  2PG2 A;  1BR1 A;  2UYI A;  2X7C A;  2IEH A;  4PJM A;  1VOM A;  1FMV A;  3L1C A;  4E7S A;  4PJJ A;  2OWM A;  3T0Q A;  4BXN A;  4ZCA A;  1D0Y A;  1CZ7 A;  2ZFI A;  2Q2Z A;  3KAR A;  1D0X A;  2XT3 A;  2G1Q A;  4Y05 A;  4ZHI A;  1MMD A;  1V8J A;  2NCD A;  2Y65 A;  2V26 A;  2X7D A;  4LNU K;  3KEN A;  4GKR A;  2HEH A;  4PK4 A;  4UBF A;  2GM1 A;  3K5E A;  2Y5W A;  4A50 A;  1GOJ A;  2MYS A;  4HNA K;  2GRY A;  2UYM A;  2VB6 A;  5HLE A;  2X7E A;  3NWN A;  1VFV A;  1LVK A;  3HQD A;  3L9H A;  1MNE A;  2VVG A;  3KIN A;  4AS7 A;  1N6M A;  2FL2 A;  3PXN A;  2Q2Y A;  3U06 A;  3B6V A;  3B6U A;  4A51 A;  5LT0 A;  1FMW A;  2ZFL A;  3DC4 A;  4A1Z A;  4BN2 A;  4B7B A;  1LKX A;  1BR4 A;  2ZFM A;  3ZCW A;  5LT4 A;  2KIN A;  1F9V A;  3DCB A;  1I5S A;  4DBR A;  2VAS A;  4PFO A;  1F9U A;  4H1G A;  4A28 A;  1D0Z A;  3ZFC A;  1YRS A;  2X51 A;  1D1C A;  1T5C A;  1F9W A;  4PJL A;  2X2R A;  2FKY A;  3K3B A;  1MMA A;  1RY6 A;  1BG2 A;  4AP0 A;  3GBJ A;  2ZFJ A;  3LRE A;  3BFN A;  1I6I A;  5GSZ A;  3H4S A;  4ETP A;  3CJO A;  2FME A;  1D1A A;  1D1B A;  4PFP A;  1Q0B A;  1SDM A;  4ANJ A;  4BBG A;  2WOG A; 
#chains in the Genus database with same CATH topology
 3CNZ A;  3WRD A;  4A14 A;  1G8X A;  4E7Z A;  1X88 A;  3WPN A;  3ZFD A;  5LT2 A;  1MMN A;  2ZFK A;  1KK7 A;  2XAE A;  5LT1 A;  1VFZ A;  2FL6 A;  1BR2 A;  1V8K A;  1F9T A;  1MKJ A;  3X2T A;  4FRZ A;  4GKP A;  4A5Y A;  1II6 A;  1MMG A;  5LT3 A;  3COB A;  1VFX A;  1VFW A;  4PJN A;  4DBQ A;  2PG2 A;  1BR1 A;  2UYI A;  2X7C A;  2IEH A;  4PJM A;  1VOM A;  1FMV A;  3L1C A;  4E7S A;  4PJJ A;  2OWM A;  3T0Q A;  4BXN A;  4ZCA A;  1D0Y A;  1CZ7 A;  2O0A A;  2ZFI A;  2Q2Z A;  3KAR A;  1D0X A;  2XT3 A;  2G1Q A;  4Y05 A;  4ZHI A;  1MMD A;  1V8J A;  2NCD A;  2Y65 A;  2V26 A;  2X7D A;  4LNU K;  3KEN A;  4GKR A;  2HEH A;  4PK4 A;  4UBF A;  2GM1 A;  3K5E A;  2Y5W A;  4A50 A;  1GOJ A;  2MYS A;  4ETP B;  4HNA K;  2GRY A;  2UYM A;  2VB6 A;  5HLE A;  2X7E A;  3NWN A;  1VFV A;  1LVK A;  3HQD A;  3L9H A;  1MNE A;  2VVG A;  3KIN A;  4AS7 A;  1N6M A;  2FL2 A;  3PXN A;  2Q2Y A;  3U06 A;  3B6V A;  3B6U A;  4A51 A;  5LT0 A;  1FMW A;  2ZFL A;  3DC4 A;  4A1Z A;  4BN2 A;  4B7B A;  1LKX A;  1BR4 A;  2ZFM A;  3ZCW A;  5LT4 A;  2KIN A;  1F9V A;  3DCB A;  1I5S A;  4DBR A;  2VAS A;  4PFO A;  1F9U A;  4H1G A;  4A28 A;  1D0Z A;  3ZFC A;  1YRS A;  2X51 A;  1D1C A;  1T5C A;  1F9W A;  4PJL A;  2X2R A;  2FKY A;  3K3B A;  1MMA A;  1RY6 A;  4GKQ A;  1BG2 A;  4AP0 A;  3GBJ A;  2ZFJ A;  3LRE A;  3BFN A;  1I6I A;  5GSZ A;  3H4S A;  4ETP A;  3CJO A;  2FME A;  1D1A A;  1D1B A;  4PFP A;  1Q0B A;  1SDM A;  4ANJ A;  4BBG A;  2WOG A; 
#chains in the Genus database with same CATH homology
 3CNZ A;  3WRD A;  4A14 A;  1G8X A;  4E7Z A;  1X88 A;  3WPN A;  3ZFD A;  5LT2 A;  1MMN A;  2ZFK A;  1KK7 A;  2XAE A;  5LT1 A;  1VFZ A;  2FL6 A;  1BR2 A;  1V8K A;  1F9T A;  1MKJ A;  3X2T A;  4FRZ A;  4A5Y A;  1II6 A;  1MMG A;  5LT3 A;  3COB A;  1VFX A;  1VFW A;  4PJN A;  4DBQ A;  2PG2 A;  1BR1 A;  2UYI A;  2X7C A;  2IEH A;  4PJM A;  1VOM A;  1FMV A;  3L1C A;  4E7S A;  4PJJ A;  2OWM A;  3T0Q A;  4BXN A;  4ZCA A;  1D0Y A;  1CZ7 A;  2ZFI A;  2Q2Z A;  3KAR A;  1D0X A;  2XT3 A;  2G1Q A;  4Y05 A;  4ZHI A;  1MMD A;  1V8J A;  2NCD A;  2Y65 A;  2V26 A;  2X7D A;  4LNU K;  3KEN A;  4GKR A;  2HEH A;  4PK4 A;  4UBF A;  2GM1 A;  3K5E A;  2Y5W A;  4A50 A;  1GOJ A;  2MYS A;  4HNA K;  2GRY A;  2UYM A;  2VB6 A;  5HLE A;  2X7E A;  3NWN A;  1VFV A;  1LVK A;  3HQD A;  3L9H A;  1MNE A;  2VVG A;  3KIN A;  4AS7 A;  1N6M A;  2FL2 A;  3PXN A;  2Q2Y A;  3U06 A;  3B6V A;  3B6U A;  4A51 A;  5LT0 A;  1FMW A;  2ZFL A;  3DC4 A;  4A1Z A;  4BN2 A;  4B7B A;  1LKX A;  1BR4 A;  2ZFM A;  3ZCW A;  5LT4 A;  2KIN A;  1F9V A;  3DCB A;  1I5S A;  4DBR A;  2VAS A;  4PFO A;  1F9U A;  4H1G A;  4A28 A;  1D0Z A;  3ZFC A;  1YRS A;  2X51 A;  1D1C A;  1T5C A;  1F9W A;  4PJL A;  2X2R A;  2FKY A;  3K3B A;  1MMA A;  1RY6 A;  1BG2 A;  4AP0 A;  3GBJ A;  2ZFJ A;  3LRE A;  3BFN A;  1I6I A;  5GSZ A;  3H4S A;  4ETP A;  3CJO A;  2FME A;  1D1A A;  1D1B A;  4PFP A;  1Q0B A;  1SDM A;  4ANJ A;  4BBG A;  2WOG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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