3KENA

Human eg5 in complex with s-trityl-l-cysteine
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
349
structure length
333
Chain Sequence
b'NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVN'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Kinesin-like protein KIF11
publication title Allosteric drug discrimination is coupled to mechanochemical changes in the kinesin-5 motor core.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Motor protein
total genus 108
structure length 333
sequence length 349
ec nomenclature
pdb deposition date 2009-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 3kenA00
2X7EA 3LREA 1CZ7A 2Y65A 1BR2A 1YRSA 4BXNA 4PK4A 2ZFIA 4A51A 2ZFMA 3ZCWA 4B7BA 4BN2A 1V8JA 2Q2ZA 2X7DA 3KENA 4ZCAA 3B6VA 1F9TA 3T0QA 1MMAA 1I6IA 1MMNA 2FL6A 2KINA 2VASA 5LT4A 1II6A 2FL2A 3ZFCA 1VFXA 2WOGA 1V8KA 1F9VA 2X2RA 2X7CA 5HLEA 2ZFLA 5LT0A 1BR4A 4LNUK 4AS7A 4PJJA 4A1ZA 2FMEA 3GBJA 1BG2A 1MMDA 1BR1A 3U06A 4PJNA 5LT3A 1D1BA 1D1CA 1N6MA 3NWNA 3H4SA 1GOJA 4DBQA 4BBGA 2ZFKA 1G8XA 1VFZA 3WPNA 2XT3A 4GKRA 2HEHA 1VOMA 4PJLA 2IEHA 1F9WA 4ETPA 1LVKA 2Q2YA 3CJOA 3ZFDA 4ANJA 4UBFA 4PJMA 5GSZA 2UYIA 4E7SA 1X88A 3CNZA 1MNEA 2GRYA 4HNAK 2FKYA 3L1CA 3COBA 4A28A 1F9UA 1SDMA 3KARA 2OWMA 4H1GA 1FMVA 4FRZA 1MKJA 5LT1A 4ZHIA 1T5CA 2Y5WA 1VFWA 4PFOA 4A50A 1D0XA 1KK7A 2G1QA 2XAEA 3WRDA 3BFNA 1FMWA 2V26A 2NCDA 3B6UA 1D0ZA 2UYMA 1D0YA 3DCBA 3HQDA 3X2TA 3L9HA 4AP0A 2PG2A 2X51A 4DBRA 1D1AA 1RY6A 4A14A 3K3BA 3KINA 4E7ZA 4A5YA 2GM1A 2VVGA 1MMGA 1LKXA 3K5EA 3DC4A 1VFVA 1Q0BA 4PFPA 2VB6A 3PXNA 4Y05A 2ZFJA 1I5SA 2MYSA 5LT2A
chains in the Genus database with same CATH superfamily
2X7EA 3LREA 1CZ7A 2Y65A 1BR2A 1YRSA 4BXNA 4PK4A 2ZFIA 4A51A 2ZFMA 3ZCWA 4B7BA 4BN2A 1V8JA 2Q2ZA 2X7DA 3KENA 4ZCAA 3B6VA 1F9TA 3T0QA 1MMAA 1I6IA 1MMNA 2FL6A 2KINA 2VASA 5LT4A 1II6A 2FL2A 3ZFCA 1VFXA 2WOGA 1V8KA 1F9VA 2X2RA 2X7CA 5HLEA 2ZFLA 5LT0A 1BR4A 4LNUK 4AS7A 4PJJA 4A1ZA 2FMEA 3GBJA 1BG2A 1MMDA 1BR1A 3U06A 4PJNA 5LT3A 1D1BA 1D1CA 1N6MA 3NWNA 3H4SA 1GOJA 4DBQA 4BBGA 2ZFKA 1G8XA 1VFZA 2O0AA 3WPNA 2XT3A 4GKRA 2HEHA 1VOMA 4PJLA 2IEHA 1F9WA 4ETPA 1LVKA 2Q2YA 3CJOA 3ZFDA 4ANJA 4UBFA 4PJMA 5GSZA 2UYIA 4E7SA 1X88A 3CNZA 1MNEA 2GRYA 4HNAK 2FKYA 3L1CA 4ETPB 3COBA 4A28A 1F9UA 1SDMA 3KARA 2OWMA 4H1GA 1FMVA 4FRZA 1MKJA 5LT1A 4ZHIA 1T5CA 2Y5WA 1VFWA 4PFOA 4A50A 1D0XA 1KK7A 2G1QA 2XAEA 3WRDA 3BFNA 1FMWA 2V26A 2NCDA 4GKQA 3B6UA 4GKPA 1D0ZA 2UYMA 1D0YA 3DCBA 3HQDA 3X2TA 3L9HA 4AP0A 2PG2A 2X51A 4DBRA 1D1AA 1RY6A 4A14A 3K3BA 3KINA 4E7ZA 4A5YA 2GM1A 2VVGA 1MMGA 1LKXA 3K5EA 3DC4A 1VFVA 1Q0BA 4PFPA 2VB6A 3PXNA 4Y05A 2ZFJA 1I5SA 2MYSA 5LT2A
chains in the Genus database with same CATH topology
2X7EA 3LREA 1CZ7A 2Y65A 1BR2A 1YRSA 4BXNA 4PK4A 2ZFIA 4A51A 2ZFMA 3ZCWA 4B7BA 4BN2A 1V8JA 2Q2ZA 2X7DA 3KENA 4ZCAA 3B6VA 1F9TA 3T0QA 1MMAA 1I6IA 1MMNA 2FL6A 2KINA 2VASA 5LT4A 1II6A 2FL2A 3ZFCA 1VFXA 2WOGA 1V8KA 1F9VA 2X2RA 2X7CA 5HLEA 2ZFLA 5LT0A 1BR4A 4LNUK 4AS7A 4PJJA 4A1ZA 2FMEA 3GBJA 1BG2A 1MMDA 1BR1A 3U06A 4PJNA 5LT3A 1D1BA 1D1CA 1N6MA 3NWNA 3H4SA 1GOJA 4DBQA 4BBGA 2ZFKA 1G8XA 1VFZA 3WPNA 2XT3A 4GKRA 2HEHA 1VOMA 4PJLA 2IEHA 1F9WA 4ETPA 1LVKA 2Q2YA 3CJOA 3ZFDA 4ANJA 4UBFA 4PJMA 5GSZA 2UYIA 4E7SA 1X88A 3CNZA 1MNEA 2GRYA 4HNAK 2FKYA 3L1CA 3COBA 4A28A 1F9UA 1SDMA 3KARA 2OWMA 4H1GA 1FMVA 4FRZA 1MKJA 5LT1A 4ZHIA 1T5CA 2Y5WA 1VFWA 4PFOA 4A50A 1D0XA 1KK7A 2G1QA 2XAEA 3WRDA 3BFNA 1FMWA 2V26A 2NCDA 3B6UA 1D0ZA 2UYMA 1D0YA 3DCBA 3HQDA 3X2TA 3L9HA 4AP0A 2PG2A 2X51A 4DBRA 1D1AA 1RY6A 4A14A 3K3BA 3KINA 4E7ZA 4A5YA 2GM1A 2VVGA 1MMGA 1LKXA 3K5EA 3DC4A 1VFVA 1Q0BA 4PFPA 2VB6A 3PXNA 4Y05A 2ZFJA 1I5SA 2MYSA 5LT2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X7E A;  3LRE A;  1CZ7 A;  2Y65 A;  1BR2 A;  1YRS A;  4BXN A;  4PK4 A;  2ZFI A;  4A51 A;  2ZFM A;  3ZCW A;  4B7B A;  4BN2 A;  1V8J A;  2Q2Z A;  2X7D A;  3KEN A;  4ZCA A;  3B6V A;  1F9T A;  3T0Q A;  1MMA A;  1I6I A;  1MMN A;  2FL6 A;  2KIN A;  2VAS A;  5LT4 A;  1II6 A;  2FL2 A;  3ZFC A;  1VFX A;  2WOG A;  1V8K A;  1F9V A;  2X2R A;  2X7C A;  5HLE A;  2ZFL A;  5LT0 A;  1BR4 A;  4LNU K;  4AS7 A;  4PJJ A;  4A1Z A;  2FME A;  3GBJ A;  1BG2 A;  1MMD A;  1BR1 A;  3U06 A;  4PJN A;  5LT3 A;  1D1B A;  1D1C A;  1N6M A;  3NWN A;  3H4S A;  1GOJ A;  4DBQ A;  4BBG A;  2ZFK A;  1G8X A;  1VFZ A;  3WPN A;  2XT3 A;  4GKR A;  2HEH A;  1VOM A;  4PJL A;  2IEH A;  1F9W A;  4ETP A;  1LVK A;  2Q2Y A;  3CJO A;  3ZFD A;  4ANJ A;  4UBF A;  4PJM A;  5GSZ A;  2UYI A;  4E7S A;  1X88 A;  3CNZ A;  1MNE A;  2GRY A;  4HNA K;  2FKY A;  3L1C A;  3COB A;  4A28 A;  1F9U A;  1SDM A;  3KAR A;  2OWM A;  4H1G A;  1FMV A;  4FRZ A;  1MKJ A;  5LT1 A;  4ZHI A;  1T5C A;  2Y5W A;  1VFW A;  4PFO A;  4A50 A;  1D0X A;  1KK7 A;  2G1Q A;  2XAE A;  3WRD A;  3BFN A;  1FMW A;  2V26 A;  2NCD A;  3B6U A;  1D0Z A;  2UYM A;  1D0Y A;  3DCB A;  3HQD A;  3X2T A;  3L9H A;  4AP0 A;  2PG2 A;  2X51 A;  4DBR A;  1D1A A;  1RY6 A;  4A14 A;  3K3B A;  3KIN A;  4E7Z A;  4A5Y A;  2GM1 A;  2VVG A;  1MMG A;  1LKX A;  3K5E A;  3DC4 A;  1VFV A;  1Q0B A;  4PFP A;  2VB6 A;  3PXN A;  4Y05 A;  2ZFJ A;  1I5S A;  2MYS A;  5LT2 A; 
#chains in the Genus database with same CATH topology
 2X7E A;  3LRE A;  1CZ7 A;  2Y65 A;  1BR2 A;  1YRS A;  4BXN A;  4PK4 A;  2ZFI A;  4A51 A;  2ZFM A;  3ZCW A;  4B7B A;  4BN2 A;  1V8J A;  2Q2Z A;  2X7D A;  3KEN A;  4ZCA A;  3B6V A;  1F9T A;  3T0Q A;  1MMA A;  1I6I A;  1MMN A;  2FL6 A;  2KIN A;  2VAS A;  5LT4 A;  1II6 A;  2FL2 A;  3ZFC A;  1VFX A;  2WOG A;  1V8K A;  1F9V A;  2X2R A;  2X7C A;  5HLE A;  2ZFL A;  5LT0 A;  1BR4 A;  4LNU K;  4AS7 A;  4PJJ A;  4A1Z A;  2FME A;  3GBJ A;  1BG2 A;  1MMD A;  1BR1 A;  3U06 A;  4PJN A;  5LT3 A;  1D1B A;  1D1C A;  1N6M A;  3NWN A;  3H4S A;  1GOJ A;  4DBQ A;  4BBG A;  2ZFK A;  1G8X A;  1VFZ A;  2O0A A;  3WPN A;  2XT3 A;  4GKR A;  2HEH A;  1VOM A;  4PJL A;  2IEH A;  1F9W A;  4ETP A;  1LVK A;  2Q2Y A;  3CJO A;  3ZFD A;  4ANJ A;  4UBF A;  4PJM A;  5GSZ A;  2UYI A;  4E7S A;  1X88 A;  3CNZ A;  1MNE A;  2GRY A;  4HNA K;  2FKY A;  3L1C A;  4ETP B;  3COB A;  4A28 A;  1F9U A;  1SDM A;  3KAR A;  2OWM A;  4H1G A;  1FMV A;  4FRZ A;  1MKJ A;  5LT1 A;  4ZHI A;  1T5C A;  2Y5W A;  1VFW A;  4PFO A;  4A50 A;  1D0X A;  1KK7 A;  2G1Q A;  2XAE A;  3WRD A;  3BFN A;  1FMW A;  2V26 A;  2NCD A;  4GKQ A;  3B6U A;  4GKP A;  1D0Z A;  2UYM A;  1D0Y A;  3DCB A;  3HQD A;  3X2T A;  3L9H A;  4AP0 A;  2PG2 A;  2X51 A;  4DBR A;  1D1A A;  1RY6 A;  4A14 A;  3K3B A;  3KIN A;  4E7Z A;  4A5Y A;  2GM1 A;  2VVG A;  1MMG A;  1LKX A;  3K5E A;  3DC4 A;  1VFV A;  1Q0B A;  4PFP A;  2VB6 A;  3PXN A;  4Y05 A;  2ZFJ A;  1I5S A;  2MYS A;  5LT2 A; 
#chains in the Genus database with same CATH homology
 2X7E A;  3LRE A;  1CZ7 A;  2Y65 A;  1BR2 A;  1YRS A;  4BXN A;  4PK4 A;  2ZFI A;  4A51 A;  2ZFM A;  3ZCW A;  4B7B A;  4BN2 A;  1V8J A;  2Q2Z A;  2X7D A;  3KEN A;  4ZCA A;  3B6V A;  1F9T A;  3T0Q A;  1MMA A;  1I6I A;  1MMN A;  2FL6 A;  2KIN A;  2VAS A;  5LT4 A;  1II6 A;  2FL2 A;  3ZFC A;  1VFX A;  2WOG A;  1V8K A;  1F9V A;  2X2R A;  2X7C A;  5HLE A;  2ZFL A;  5LT0 A;  1BR4 A;  4LNU K;  4AS7 A;  4PJJ A;  4A1Z A;  2FME A;  3GBJ A;  1BG2 A;  1MMD A;  1BR1 A;  3U06 A;  4PJN A;  5LT3 A;  1D1B A;  1D1C A;  1N6M A;  3NWN A;  3H4S A;  1GOJ A;  4DBQ A;  4BBG A;  2ZFK A;  1G8X A;  1VFZ A;  3WPN A;  2XT3 A;  4GKR A;  2HEH A;  1VOM A;  4PJL A;  2IEH A;  1F9W A;  4ETP A;  1LVK A;  2Q2Y A;  3CJO A;  3ZFD A;  4ANJ A;  4UBF A;  4PJM A;  5GSZ A;  2UYI A;  4E7S A;  1X88 A;  3CNZ A;  1MNE A;  2GRY A;  4HNA K;  2FKY A;  3L1C A;  3COB A;  4A28 A;  1F9U A;  1SDM A;  3KAR A;  2OWM A;  4H1G A;  1FMV A;  4FRZ A;  1MKJ A;  5LT1 A;  4ZHI A;  1T5C A;  2Y5W A;  1VFW A;  4PFO A;  4A50 A;  1D0X A;  1KK7 A;  2G1Q A;  2XAE A;  3WRD A;  3BFN A;  1FMW A;  2V26 A;  2NCD A;  3B6U A;  1D0Z A;  2UYM A;  1D0Y A;  3DCB A;  3HQD A;  3X2T A;  3L9H A;  4AP0 A;  2PG2 A;  2X51 A;  4DBR A;  1D1A A;  1RY6 A;  4A14 A;  3K3B A;  3KIN A;  4E7Z A;  4A5Y A;  2GM1 A;  2VVG A;  1MMG A;  1LKX A;  3K5E A;  3DC4 A;  1VFV A;  1Q0B A;  4PFP A;  2VB6 A;  3PXN A;  4Y05 A;  2ZFJ A;  1I5S A;  2MYS A;  5LT2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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