1F9VA

Crystal structures of mutants reveal a signalling pathway for activation of the kinesin motor atpase
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
342
structure length
313
Chain Sequence
GNIRVYCRIRPALKNLENSDTSLINVNEFDDNSGVQSMEVTKIQNTAQVHEFKFDKIFDQQDTNVDVFKEVGQLVQSSLDGYNVCIFAYGQTGSGKTFTMLNPGDGIIPSTISHIFNWINKLKTKGWDYKVNCEFIEIYNENIVDLLRKHEIRHDQETKTTTITNVTSCKLESEEMVEIILKKANEHSSASHSIFIIHLSGSNAGAHSYGTLNLVDLAGSERINVSQVVGDRLRETQNINKSLSCLGDVIHALGQPDRHIPFRNSKLTYLLQYSLTGDSKTLMFVNISPSSSHINETLNSLRFASKVNSTRLV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A structural pathway for activation of the kinesin motor ATPase.
pubmed doi rcsb
molecule tags Contractile protein
source organism Saccharomyces cerevisiae
molecule keywords KINESIN-LIKE PROTEIN KAR3
total genus 105
structure length 313
sequence length 342
ec nomenclature
pdb deposition date 2000-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 1f9vA00
2Q2YA 1FMWA 2VB6A 3GBJA 3K5EA 5LT1A 4LNUK 4ANJA 3ZCWA 1N6MA 1MMDA 3ZFDA 4HNAK 1D1BA 1RY6A 2ZFJA 1D0ZA 1KK7A 5LT4A 1T5CA 2FL6A 2ZFIA 4FRZA 2GRYA 3WRDA 4H1GA 1VFVA 3K3BA 2X7EA 2WOGA 3L9HA 4PJMA 2NCDA 2OWMA 1Q0BA 3DCBA 4UBFA 5LT0A 1VFXA 1MNEA 2X7CA 4A28A 1MKJA 4AS7A 2X2RA 4A5YA 2Y65A 3COBA 5GSZA 1FMVA 2GM1A 4PJNA 3H4SA 2VASA 3DC4A 2Q2ZA 3CNZA 4BXNA 3B6VA 3CJOA 1D0YA 4AP0A 2FKYA 1D1CA 4Y05A 4PK4A 2X7DA 2PG2A 1CZ7A 4A50A 5LT2A 1BR4A 2FL2A 1X88A 3KARA 1GOJA 5HLEA 3HQDA 1BR1A 2ZFLA 1MMGA 2Y5WA 1I6IA 4B7BA 3WPNA 1VFWA 2UYMA 1V8KA 4BBGA 2XT3A 4DBRA 4A51A 5LT3A 4GKRA 2MYSA 4E7ZA 4ETPA 2XAEA 3B6UA 3U06A 2ZFKA 1VFZA 2UYIA 1SDMA 2HEHA 3LREA 1F9TA 1II6A 2G1QA 1D0XA 1LVKA 1LKXA 3X2TA 2X51A 4ZCAA 4ZHIA 1VOMA 2V26A 4PFPA 3KENA 2IEHA 4PJJA 1MMAA 1BG2A 1I5SA 1F9VA 4E7SA 2VVGA 1F9WA 4PFOA 2KINA 1BR2A 1G8XA 3KINA 3L1CA 3ZFCA 4PJLA 1D1AA 4A1ZA 1MMNA 4A14A 3PXNA 3BFNA 3T0QA 1F9UA 1V8JA 4DBQA 4BN2A 1YRSA 2ZFMA 3NWNA 2FMEA
chains in the Genus database with same CATH superfamily
2Q2YA 1FMWA 2VB6A 3GBJA 3K5EA 5LT1A 4LNUK 4ANJA 3ZCWA 1N6MA 2O0AA 1MMDA 3ZFDA 4HNAK 1D1BA 1RY6A 2ZFJA 1D0ZA 1KK7A 5LT4A 1T5CA 2FL6A 2ZFIA 4FRZA 2GRYA 3WRDA 4H1GA 1VFVA 3K3BA 2X7EA 2WOGA 3L9HA 4PJMA 2NCDA 2OWMA 1Q0BA 3DCBA 4UBFA 5LT0A 1VFXA 1MNEA 2X7CA 4A28A 1MKJA 4AS7A 2X2RA 4A5YA 2Y65A 3COBA 5GSZA 1FMVA 2GM1A 4PJNA 3H4SA 2VASA 3DC4A 2Q2ZA 3CNZA 4BXNA 3B6VA 3CJOA 1D0YA 4AP0A 2FKYA 1D1CA 4Y05A 4PK4A 2X7DA 2PG2A 1CZ7A 4A50A 5LT2A 1BR4A 2FL2A 1X88A 3KARA 1GOJA 5HLEA 3HQDA 1BR1A 2ZFLA 1MMGA 2Y5WA 1I6IA 4GKPA 4B7BA 3WPNA 1VFWA 2UYMA 1V8KA 4BBGA 2XT3A 4DBRA 4A51A 5LT3A 4GKRA 2MYSA 4E7ZA 4ETPA 2XAEA 3B6UA 3U06A 2ZFKA 1VFZA 2UYIA 1SDMA 2HEHA 3LREA 1F9TA 4GKQA 1II6A 2G1QA 1D0XA 1LVKA 1LKXA 3X2TA 2X51A 4ZCAA 4ZHIA 1VOMA 2V26A 4PFPA 3KENA 2IEHA 4PJJA 1MMAA 1BG2A 1I5SA 1F9VA 4ETPB 4E7SA 2VVGA 1F9WA 4PFOA 2KINA 1BR2A 1G8XA 3KINA 3L1CA 3ZFCA 4PJLA 1D1AA 4A1ZA 1MMNA 4A14A 3PXNA 3BFNA 3T0QA 1F9UA 1V8JA 4DBQA 4BN2A 1YRSA 2ZFMA 3NWNA 2FMEA
chains in the Genus database with same CATH topology
2Q2YA 1FMWA 2VB6A 3GBJA 3K5EA 5LT1A 4LNUK 4ANJA 3ZCWA 1N6MA 1MMDA 3ZFDA 4HNAK 1D1BA 1RY6A 2ZFJA 1D0ZA 1KK7A 5LT4A 1T5CA 2FL6A 2ZFIA 4FRZA 2GRYA 3WRDA 4H1GA 1VFVA 3K3BA 2X7EA 2WOGA 3L9HA 4PJMA 2NCDA 2OWMA 1Q0BA 3DCBA 4UBFA 5LT0A 1VFXA 1MNEA 2X7CA 4A28A 1MKJA 4AS7A 2X2RA 4A5YA 2Y65A 3COBA 5GSZA 1FMVA 2GM1A 4PJNA 3H4SA 2VASA 3DC4A 2Q2ZA 3CNZA 4BXNA 3B6VA 3CJOA 1D0YA 4AP0A 2FKYA 1D1CA 4Y05A 4PK4A 2X7DA 2PG2A 1CZ7A 4A50A 5LT2A 1BR4A 2FL2A 1X88A 3KARA 1GOJA 5HLEA 3HQDA 1BR1A 2ZFLA 1MMGA 2Y5WA 1I6IA 4B7BA 3WPNA 1VFWA 2UYMA 1V8KA 4BBGA 2XT3A 4DBRA 4A51A 5LT3A 4GKRA 2MYSA 4E7ZA 4ETPA 2XAEA 3B6UA 3U06A 2ZFKA 1VFZA 2UYIA 1SDMA 2HEHA 3LREA 1F9TA 1II6A 2G1QA 1D0XA 1LVKA 1LKXA 3X2TA 2X51A 4ZCAA 4ZHIA 1VOMA 2V26A 4PFPA 3KENA 2IEHA 4PJJA 1MMAA 1BG2A 1I5SA 1F9VA 4E7SA 2VVGA 1F9WA 4PFOA 2KINA 1BR2A 1G8XA 3KINA 3L1CA 3ZFCA 4PJLA 1D1AA 4A1ZA 1MMNA 4A14A 3PXNA 3BFNA 3T0QA 1F9UA 1V8JA 4DBQA 4BN2A 1YRSA 2ZFMA 3NWNA 2FMEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Q2Y A;  1FMW A;  2VB6 A;  3GBJ A;  3K5E A;  5LT1 A;  4LNU K;  4ANJ A;  3ZCW A;  1N6M A;  1MMD A;  3ZFD A;  4HNA K;  1D1B A;  1RY6 A;  2ZFJ A;  1D0Z A;  1KK7 A;  5LT4 A;  1T5C A;  2FL6 A;  2ZFI A;  4FRZ A;  2GRY A;  3WRD A;  4H1G A;  1VFV A;  3K3B A;  2X7E A;  2WOG A;  3L9H A;  4PJM A;  2NCD A;  2OWM A;  1Q0B A;  3DCB A;  4UBF A;  5LT0 A;  1VFX A;  1MNE A;  2X7C A;  4A28 A;  1MKJ A;  4AS7 A;  2X2R A;  4A5Y A;  2Y65 A;  3COB A;  5GSZ A;  1FMV A;  2GM1 A;  4PJN A;  3H4S A;  2VAS A;  3DC4 A;  2Q2Z A;  3CNZ A;  4BXN A;  3B6V A;  3CJO A;  1D0Y A;  4AP0 A;  2FKY A;  1D1C A;  4Y05 A;  4PK4 A;  2X7D A;  2PG2 A;  1CZ7 A;  4A50 A;  5LT2 A;  1BR4 A;  2FL2 A;  1X88 A;  3KAR A;  1GOJ A;  5HLE A;  3HQD A;  1BR1 A;  2ZFL A;  1MMG A;  2Y5W A;  1I6I A;  4B7B A;  3WPN A;  1VFW A;  2UYM A;  1V8K A;  4BBG A;  2XT3 A;  4DBR A;  4A51 A;  5LT3 A;  4GKR A;  2MYS A;  4E7Z A;  4ETP A;  2XAE A;  3B6U A;  3U06 A;  2ZFK A;  1VFZ A;  2UYI A;  1SDM A;  2HEH A;  3LRE A;  1F9T A;  1II6 A;  2G1Q A;  1D0X A;  1LVK A;  1LKX A;  3X2T A;  2X51 A;  4ZCA A;  4ZHI A;  1VOM A;  2V26 A;  4PFP A;  3KEN A;  2IEH A;  4PJJ A;  1MMA A;  1BG2 A;  1I5S A;  1F9V A;  4E7S A;  2VVG A;  1F9W A;  4PFO A;  2KIN A;  1BR2 A;  1G8X A;  3KIN A;  3L1C A;  3ZFC A;  4PJL A;  1D1A A;  4A1Z A;  1MMN A;  4A14 A;  3PXN A;  3BFN A;  3T0Q A;  1F9U A;  1V8J A;  4DBQ A;  4BN2 A;  1YRS A;  2ZFM A;  3NWN A;  2FME A; 
#chains in the Genus database with same CATH topology
 2Q2Y A;  1FMW A;  2VB6 A;  3GBJ A;  3K5E A;  5LT1 A;  4LNU K;  4ANJ A;  3ZCW A;  1N6M A;  2O0A A;  1MMD A;  3ZFD A;  4HNA K;  1D1B A;  1RY6 A;  2ZFJ A;  1D0Z A;  1KK7 A;  5LT4 A;  1T5C A;  2FL6 A;  2ZFI A;  4FRZ A;  2GRY A;  3WRD A;  4H1G A;  1VFV A;  3K3B A;  2X7E A;  2WOG A;  3L9H A;  4PJM A;  2NCD A;  2OWM A;  1Q0B A;  3DCB A;  4UBF A;  5LT0 A;  1VFX A;  1MNE A;  2X7C A;  4A28 A;  1MKJ A;  4AS7 A;  2X2R A;  4A5Y A;  2Y65 A;  3COB A;  5GSZ A;  1FMV A;  2GM1 A;  4PJN A;  3H4S A;  2VAS A;  3DC4 A;  2Q2Z A;  3CNZ A;  4BXN A;  3B6V A;  3CJO A;  1D0Y A;  4AP0 A;  2FKY A;  1D1C A;  4Y05 A;  4PK4 A;  2X7D A;  2PG2 A;  1CZ7 A;  4A50 A;  5LT2 A;  1BR4 A;  2FL2 A;  1X88 A;  3KAR A;  1GOJ A;  5HLE A;  3HQD A;  1BR1 A;  2ZFL A;  1MMG A;  2Y5W A;  1I6I A;  4GKP A;  4B7B A;  3WPN A;  1VFW A;  2UYM A;  1V8K A;  4BBG A;  2XT3 A;  4DBR A;  4A51 A;  5LT3 A;  4GKR A;  2MYS A;  4E7Z A;  4ETP A;  2XAE A;  3B6U A;  3U06 A;  2ZFK A;  1VFZ A;  2UYI A;  1SDM A;  2HEH A;  3LRE A;  1F9T A;  4GKQ A;  1II6 A;  2G1Q A;  1D0X A;  1LVK A;  1LKX A;  3X2T A;  2X51 A;  4ZCA A;  4ZHI A;  1VOM A;  2V26 A;  4PFP A;  3KEN A;  2IEH A;  4PJJ A;  1MMA A;  1BG2 A;  1I5S A;  1F9V A;  4ETP B;  4E7S A;  2VVG A;  1F9W A;  4PFO A;  2KIN A;  1BR2 A;  1G8X A;  3KIN A;  3L1C A;  3ZFC A;  4PJL A;  1D1A A;  4A1Z A;  1MMN A;  4A14 A;  3PXN A;  3BFN A;  3T0Q A;  1F9U A;  1V8J A;  4DBQ A;  4BN2 A;  1YRS A;  2ZFM A;  3NWN A;  2FME A; 
#chains in the Genus database with same CATH homology
 2Q2Y A;  1FMW A;  2VB6 A;  3GBJ A;  3K5E A;  5LT1 A;  4LNU K;  4ANJ A;  3ZCW A;  1N6M A;  1MMD A;  3ZFD A;  4HNA K;  1D1B A;  1RY6 A;  2ZFJ A;  1D0Z A;  1KK7 A;  5LT4 A;  1T5C A;  2FL6 A;  2ZFI A;  4FRZ A;  2GRY A;  3WRD A;  4H1G A;  1VFV A;  3K3B A;  2X7E A;  2WOG A;  3L9H A;  4PJM A;  2NCD A;  2OWM A;  1Q0B A;  3DCB A;  4UBF A;  5LT0 A;  1VFX A;  1MNE A;  2X7C A;  4A28 A;  1MKJ A;  4AS7 A;  2X2R A;  4A5Y A;  2Y65 A;  3COB A;  5GSZ A;  1FMV A;  2GM1 A;  4PJN A;  3H4S A;  2VAS A;  3DC4 A;  2Q2Z A;  3CNZ A;  4BXN A;  3B6V A;  3CJO A;  1D0Y A;  4AP0 A;  2FKY A;  1D1C A;  4Y05 A;  4PK4 A;  2X7D A;  2PG2 A;  1CZ7 A;  4A50 A;  5LT2 A;  1BR4 A;  2FL2 A;  1X88 A;  3KAR A;  1GOJ A;  5HLE A;  3HQD A;  1BR1 A;  2ZFL A;  1MMG A;  2Y5W A;  1I6I A;  4B7B A;  3WPN A;  1VFW A;  2UYM A;  1V8K A;  4BBG A;  2XT3 A;  4DBR A;  4A51 A;  5LT3 A;  4GKR A;  2MYS A;  4E7Z A;  4ETP A;  2XAE A;  3B6U A;  3U06 A;  2ZFK A;  1VFZ A;  2UYI A;  1SDM A;  2HEH A;  3LRE A;  1F9T A;  1II6 A;  2G1Q A;  1D0X A;  1LVK A;  1LKX A;  3X2T A;  2X51 A;  4ZCA A;  4ZHI A;  1VOM A;  2V26 A;  4PFP A;  3KEN A;  2IEH A;  4PJJ A;  1MMA A;  1BG2 A;  1I5S A;  1F9V A;  4E7S A;  2VVG A;  1F9W A;  4PFO A;  2KIN A;  1BR2 A;  1G8X A;  3KIN A;  3L1C A;  3ZFC A;  4PJL A;  1D1A A;  4A1Z A;  1MMN A;  4A14 A;  3PXN A;  3BFN A;  3T0Q A;  1F9U A;  1V8J A;  4DBQ A;  4BN2 A;  1YRS A;  2ZFM A;  3NWN A;  2FME A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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