1F9WA

Crystal structures of mutants reveal a signalling pathway for activation of the kinesin motor atpase
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
338
structure length
300
Chain Sequence
GNIRVYCRIRPALKNLEDTSLINVNEFDDNSGVQSMEVTVHEFKFDKIFDQQDTNVDVFKEVGQLVQSSLDGYNVCIFAYGQTGSGKTFTMLNPGDGIIPSTISHIFNWINKLKTKGWDYKVNCEFIEIYNENIVDLLRLKHEIRHDQETKTTTITNVTSCKLESEEMVEIILKKANKLRSTHSSRSHSIFIIHLSGSNAKTGAHSYGTLNLVDLAGSARLRETQNINKSLSCLGDVIHALGQPDSTKRHIPFRNSKLTYLLQYSLTGDSKTLMFVNISPSSSHINETLNSLRFASKVNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A structural pathway for activation of the kinesin motor ATPase.
pubmed doi rcsb
molecule tags Contractile protein
source organism Saccharomyces cerevisiae
molecule keywords KINESIN-LIKE PROTEIN KAR3
total genus 88
structure length 300
sequence length 338
chains with identical sequence B
ec nomenclature
pdb deposition date 2000-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 1f9wA00
4PJNA 4A5YA 2WOGA 3U06A 5LT0A 2FL2A 4DBQA 5LT2A 3WPNA 1I5SA 2VVGA 4AS7A 4LNUK 3NWNA 3H4SA 1BR4A 4A14A 3COBA 1D1CA 1X88A 1MNEA 4Y05A 4A50A 2FL6A 4PFOA 4ANJA 1F9VA 1VFVA 3KENA 2G1QA 2PG2A 1MKJA 1N6MA 1BR1A 4UBFA 4BXNA 5LT1A 1VFXA 2V26A 2ZFMA 1D1BA 1KK7A 3K3BA 2Y65A 1FMVA 2IEHA 2X7CA 3GBJA 1D1AA 4E7ZA 1RY6A 3K5EA 1G8XA 1MMNA 1YRSA 3HQDA 1LKXA 1Q0BA 3T0QA 4B7BA 1MMDA 1F9TA 1T5CA 2MYSA 1D0XA 4BN2A 2NCDA 2X7EA 3BFNA 3LREA 4PJMA 1I6IA 2XAEA 1D0ZA 2FKYA 3KINA 2VB6A 2Y5WA 1CZ7A 4BBGA 2X51A 2GRYA 2X7DA 3B6UA 2ZFLA 3DCBA 1VFWA 2ZFIA 2FMEA 2Q2ZA 3KARA 4DBRA 2GM1A 4FRZA 5GSZA 1BG2A 2UYIA 3ZCWA 3PXNA 3L9HA 1II6A 1VOMA 4HNAK 4PK4A 1F9WA 2HEHA 2ZFKA 4A1ZA 3ZFCA 2XT3A 1GOJA 4A28A 1SDMA 4AP0A 2OWMA 1V8KA 4H1GA 3WRDA 4ZCAA 5LT4A 4ETPA 1FMWA 1MMGA 4GKRA 4PFPA 4ZHIA 1V8JA 4PJLA 3ZFDA 3CNZA 1MMAA 2UYMA 4E7SA 2KINA 4A51A 5LT3A 2Q2YA 1BR2A 1VFZA 3L1CA 3B6VA 1D0YA 4PJJA 3CJOA 1F9UA 2X2RA 3X2TA 1LVKA 2VASA 5HLEA 2ZFJA 3DC4A
chains in the Genus database with same CATH superfamily
4PJNA 4A5YA 2WOGA 3U06A 5LT0A 2FL2A 4DBQA 5LT2A 3WPNA 1I5SA 2VVGA 4AS7A 4LNUK 3NWNA 3H4SA 1BR4A 4GKQA 4A14A 3COBA 1D1CA 1X88A 1MNEA 4Y05A 4A50A 2FL6A 4PFOA 4ANJA 1F9VA 1VFVA 3KENA 2G1QA 2PG2A 1MKJA 1N6MA 1BR1A 4UBFA 4ETPB 4BXNA 5LT1A 1VFXA 2V26A 2ZFMA 1D1BA 1KK7A 3K3BA 2Y65A 1FMVA 2IEHA 2X7CA 3GBJA 1D1AA 4E7ZA 1RY6A 3K5EA 1G8XA 1MMNA 1YRSA 3HQDA 1LKXA 1Q0BA 3T0QA 4GKPA 4B7BA 1MMDA 1F9TA 1T5CA 2MYSA 1D0XA 4BN2A 2NCDA 2X7EA 3BFNA 3LREA 4PJMA 1I6IA 2XAEA 1D0ZA 2FKYA 3KINA 2VB6A 2Y5WA 1CZ7A 4BBGA 2X51A 2GRYA 2X7DA 3B6UA 2ZFLA 3DCBA 1VFWA 2ZFIA 2FMEA 2Q2ZA 3KARA 4DBRA 2GM1A 4FRZA 5GSZA 1BG2A 2UYIA 3ZCWA 3PXNA 3L9HA 1II6A 1VOMA 4HNAK 4PK4A 1F9WA 2HEHA 2ZFKA 4A1ZA 3ZFCA 2XT3A 1GOJA 4A28A 1SDMA 4AP0A 2OWMA 1V8KA 4H1GA 3WRDA 4ZCAA 5LT4A 4ETPA 1FMWA 1MMGA 2O0AA 4GKRA 4PFPA 4ZHIA 1V8JA 4PJLA 3ZFDA 3CNZA 1MMAA 2UYMA 4E7SA 2KINA 4A51A 5LT3A 2Q2YA 1BR2A 1VFZA 3L1CA 3B6VA 1D0YA 4PJJA 3CJOA 1F9UA 2X2RA 3X2TA 1LVKA 2VASA 5HLEA 2ZFJA 3DC4A
chains in the Genus database with same CATH topology
4PJNA 4A5YA 2WOGA 3U06A 5LT0A 2FL2A 4DBQA 5LT2A 3WPNA 1I5SA 2VVGA 4AS7A 4LNUK 3NWNA 3H4SA 1BR4A 4A14A 3COBA 1D1CA 1X88A 1MNEA 4Y05A 4A50A 2FL6A 4PFOA 4ANJA 1F9VA 1VFVA 3KENA 2G1QA 2PG2A 1MKJA 1N6MA 1BR1A 4UBFA 4BXNA 5LT1A 1VFXA 2V26A 2ZFMA 1D1BA 1KK7A 3K3BA 2Y65A 1FMVA 2IEHA 2X7CA 3GBJA 1D1AA 4E7ZA 1RY6A 3K5EA 1G8XA 1MMNA 1YRSA 3HQDA 1LKXA 1Q0BA 3T0QA 4B7BA 1MMDA 1F9TA 1T5CA 2MYSA 1D0XA 4BN2A 2NCDA 2X7EA 3BFNA 3LREA 4PJMA 1I6IA 2XAEA 1D0ZA 2FKYA 3KINA 2VB6A 2Y5WA 1CZ7A 4BBGA 2X51A 2GRYA 2X7DA 3B6UA 2ZFLA 3DCBA 1VFWA 2ZFIA 2FMEA 2Q2ZA 3KARA 4DBRA 2GM1A 4FRZA 5GSZA 1BG2A 2UYIA 3ZCWA 3PXNA 3L9HA 1II6A 1VOMA 4HNAK 4PK4A 1F9WA 2HEHA 2ZFKA 4A1ZA 3ZFCA 2XT3A 1GOJA 4A28A 1SDMA 4AP0A 2OWMA 1V8KA 4H1GA 3WRDA 4ZCAA 5LT4A 4ETPA 1FMWA 1MMGA 4GKRA 4PFPA 4ZHIA 1V8JA 4PJLA 3ZFDA 3CNZA 1MMAA 2UYMA 4E7SA 2KINA 4A51A 5LT3A 2Q2YA 1BR2A 1VFZA 3L1CA 3B6VA 1D0YA 4PJJA 3CJOA 1F9UA 2X2RA 3X2TA 1LVKA 2VASA 5HLEA 2ZFJA 3DC4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PJN A;  4A5Y A;  2WOG A;  3U06 A;  5LT0 A;  2FL2 A;  4DBQ A;  5LT2 A;  3WPN A;  1I5S A;  2VVG A;  4AS7 A;  4LNU K;  3NWN A;  3H4S A;  1BR4 A;  4A14 A;  3COB A;  1D1C A;  1X88 A;  1MNE A;  4Y05 A;  4A50 A;  2FL6 A;  4PFO A;  4ANJ A;  1F9V A;  1VFV A;  3KEN A;  2G1Q A;  2PG2 A;  1MKJ A;  1N6M A;  1BR1 A;  4UBF A;  4BXN A;  5LT1 A;  1VFX A;  2V26 A;  2ZFM A;  1D1B A;  1KK7 A;  3K3B A;  2Y65 A;  1FMV A;  2IEH A;  2X7C A;  3GBJ A;  1D1A A;  4E7Z A;  1RY6 A;  3K5E A;  1G8X A;  1MMN A;  1YRS A;  3HQD A;  1LKX A;  1Q0B A;  3T0Q A;  4B7B A;  1MMD A;  1F9T A;  1T5C A;  2MYS A;  1D0X A;  4BN2 A;  2NCD A;  2X7E A;  3BFN A;  3LRE A;  4PJM A;  1I6I A;  2XAE A;  1D0Z A;  2FKY A;  3KIN A;  2VB6 A;  2Y5W A;  1CZ7 A;  4BBG A;  2X51 A;  2GRY A;  2X7D A;  3B6U A;  2ZFL A;  3DCB A;  1VFW A;  2ZFI A;  2FME A;  2Q2Z A;  3KAR A;  4DBR A;  2GM1 A;  4FRZ A;  5GSZ A;  1BG2 A;  2UYI A;  3ZCW A;  3PXN A;  3L9H A;  1II6 A;  1VOM A;  4HNA K;  4PK4 A;  1F9W A;  2HEH A;  2ZFK A;  4A1Z A;  3ZFC A;  2XT3 A;  1GOJ A;  4A28 A;  1SDM A;  4AP0 A;  2OWM A;  1V8K A;  4H1G A;  3WRD A;  4ZCA A;  5LT4 A;  4ETP A;  1FMW A;  1MMG A;  4GKR A;  4PFP A;  4ZHI A;  1V8J A;  4PJL A;  3ZFD A;  3CNZ A;  1MMA A;  2UYM A;  4E7S A;  2KIN A;  4A51 A;  5LT3 A;  2Q2Y A;  1BR2 A;  1VFZ A;  3L1C A;  3B6V A;  1D0Y A;  4PJJ A;  3CJO A;  1F9U A;  2X2R A;  3X2T A;  1LVK A;  2VAS A;  5HLE A;  2ZFJ A;  3DC4 A; 
#chains in the Genus database with same CATH topology
 4PJN A;  4A5Y A;  2WOG A;  3U06 A;  5LT0 A;  2FL2 A;  4DBQ A;  5LT2 A;  3WPN A;  1I5S A;  2VVG A;  4AS7 A;  4LNU K;  3NWN A;  3H4S A;  1BR4 A;  4GKQ A;  4A14 A;  3COB A;  1D1C A;  1X88 A;  1MNE A;  4Y05 A;  4A50 A;  2FL6 A;  4PFO A;  4ANJ A;  1F9V A;  1VFV A;  3KEN A;  2G1Q A;  2PG2 A;  1MKJ A;  1N6M A;  1BR1 A;  4UBF A;  4ETP B;  4BXN A;  5LT1 A;  1VFX A;  2V26 A;  2ZFM A;  1D1B A;  1KK7 A;  3K3B A;  2Y65 A;  1FMV A;  2IEH A;  2X7C A;  3GBJ A;  1D1A A;  4E7Z A;  1RY6 A;  3K5E A;  1G8X A;  1MMN A;  1YRS A;  3HQD A;  1LKX A;  1Q0B A;  3T0Q A;  4GKP A;  4B7B A;  1MMD A;  1F9T A;  1T5C A;  2MYS A;  1D0X A;  4BN2 A;  2NCD A;  2X7E A;  3BFN A;  3LRE A;  4PJM A;  1I6I A;  2XAE A;  1D0Z A;  2FKY A;  3KIN A;  2VB6 A;  2Y5W A;  1CZ7 A;  4BBG A;  2X51 A;  2GRY A;  2X7D A;  3B6U A;  2ZFL A;  3DCB A;  1VFW A;  2ZFI A;  2FME A;  2Q2Z A;  3KAR A;  4DBR A;  2GM1 A;  4FRZ A;  5GSZ A;  1BG2 A;  2UYI A;  3ZCW A;  3PXN A;  3L9H A;  1II6 A;  1VOM A;  4HNA K;  4PK4 A;  1F9W A;  2HEH A;  2ZFK A;  4A1Z A;  3ZFC A;  2XT3 A;  1GOJ A;  4A28 A;  1SDM A;  4AP0 A;  2OWM A;  1V8K A;  4H1G A;  3WRD A;  4ZCA A;  5LT4 A;  4ETP A;  1FMW A;  1MMG A;  2O0A A;  4GKR A;  4PFP A;  4ZHI A;  1V8J A;  4PJL A;  3ZFD A;  3CNZ A;  1MMA A;  2UYM A;  4E7S A;  2KIN A;  4A51 A;  5LT3 A;  2Q2Y A;  1BR2 A;  1VFZ A;  3L1C A;  3B6V A;  1D0Y A;  4PJJ A;  3CJO A;  1F9U A;  2X2R A;  3X2T A;  1LVK A;  2VAS A;  5HLE A;  2ZFJ A;  3DC4 A; 
#chains in the Genus database with same CATH homology
 4PJN A;  4A5Y A;  2WOG A;  3U06 A;  5LT0 A;  2FL2 A;  4DBQ A;  5LT2 A;  3WPN A;  1I5S A;  2VVG A;  4AS7 A;  4LNU K;  3NWN A;  3H4S A;  1BR4 A;  4A14 A;  3COB A;  1D1C A;  1X88 A;  1MNE A;  4Y05 A;  4A50 A;  2FL6 A;  4PFO A;  4ANJ A;  1F9V A;  1VFV A;  3KEN A;  2G1Q A;  2PG2 A;  1MKJ A;  1N6M A;  1BR1 A;  4UBF A;  4BXN A;  5LT1 A;  1VFX A;  2V26 A;  2ZFM A;  1D1B A;  1KK7 A;  3K3B A;  2Y65 A;  1FMV A;  2IEH A;  2X7C A;  3GBJ A;  1D1A A;  4E7Z A;  1RY6 A;  3K5E A;  1G8X A;  1MMN A;  1YRS A;  3HQD A;  1LKX A;  1Q0B A;  3T0Q A;  4B7B A;  1MMD A;  1F9T A;  1T5C A;  2MYS A;  1D0X A;  4BN2 A;  2NCD A;  2X7E A;  3BFN A;  3LRE A;  4PJM A;  1I6I A;  2XAE A;  1D0Z A;  2FKY A;  3KIN A;  2VB6 A;  2Y5W A;  1CZ7 A;  4BBG A;  2X51 A;  2GRY A;  2X7D A;  3B6U A;  2ZFL A;  3DCB A;  1VFW A;  2ZFI A;  2FME A;  2Q2Z A;  3KAR A;  4DBR A;  2GM1 A;  4FRZ A;  5GSZ A;  1BG2 A;  2UYI A;  3ZCW A;  3PXN A;  3L9H A;  1II6 A;  1VOM A;  4HNA K;  4PK4 A;  1F9W A;  2HEH A;  2ZFK A;  4A1Z A;  3ZFC A;  2XT3 A;  1GOJ A;  4A28 A;  1SDM A;  4AP0 A;  2OWM A;  1V8K A;  4H1G A;  3WRD A;  4ZCA A;  5LT4 A;  4ETP A;  1FMW A;  1MMG A;  4GKR A;  4PFP A;  4ZHI A;  1V8J A;  4PJL A;  3ZFD A;  3CNZ A;  1MMA A;  2UYM A;  4E7S A;  2KIN A;  4A51 A;  5LT3 A;  2Q2Y A;  1BR2 A;  1VFZ A;  3L1C A;  3B6V A;  1D0Y A;  4PJJ A;  3CJO A;  1F9U A;  2X2R A;  3X2T A;  1LVK A;  2VAS A;  5HLE A;  2ZFJ A;  3DC4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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