1F9WA

Crystal structures of mutants reveal a signalling pathway for activation of the kinesin motor atpase
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
338
structure length
300
Chain Sequence
GNIRVYCRIRPALKNLEDTSLINVNEFDDNSGVQSMEVTVHEFKFDKIFDQQDTNVDVFKEVGQLVQSSLDGYNVCIFAYGQTGSGKTFTMLNPGDGIIPSTISHIFNWINKLKTKGWDYKVNCEFIEIYNENIVDLLRLKHEIRHDQETKTTTITNVTSCKLESEEMVEIILKKANKLRSTHSSRSHSIFIIHLSGSNAKTGAHSYGTLNLVDLAGSARLRETQNINKSLSCLGDVIHALGQPDSTKRHIPFRNSKLTYLLQYSLTGDSKTLMFVNISPSSSHINETLNSLRFASKVNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A structural pathway for activation of the kinesin motor ATPase.
pubmed doi rcsb
molecule tags Contractile protein
source organism Saccharomyces cerevisiae
molecule keywords KINESIN-LIKE PROTEIN KAR3
total genus 88
structure length 300
sequence length 338
chains with identical sequence B
ec nomenclature
pdb deposition date 2000-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 1f9wA00
1MMGA 2FMEA 2V26A 1VFXA 4ANJA 1BR4A 4E7SA 3GBJA 1D1CA 5GSZA 3DC4A 4A5YA 4PJNA 4A14A 4HNAK 3ZCWA 2XAEA 4H1GA 5LT1A 1I5SA 3WRDA 2Y5WA 2Q2YA 3B6UA 1D1AA 4PJJA 3NWNA 1G8XA 4LNUK 1D1BA 4PJMA 3PXNA 1VFWA 3HQDA 1LKXA 2UYIA 3U06A 3KENA 4A1ZA 1N6MA 1Q0BA 4DBQA 2FL6A 1D0YA 3DCBA 2X7DA 4BN2A 4ETPA 5LT3A 1D0XA 3X2TA 1V8KA 1BR1A 1KK7A 1MKJA 1LVKA 5HLEA 2WOGA 3K3BA 4B7BA 2VASA 2MYSA 2X7EA 1CZ7A 4BBGA 1MMNA 3COBA 4DBRA 1F9WA 1VOMA 2ZFMA 3KARA 1SDMA 2HEHA 4PJLA 4A51A 1YRSA 2ZFIA 3K5EA 4GKRA 4UBFA 2XT3A 2FKYA 3ZFCA 4BXNA 3CJOA 4PK4A 4ZCAA 1FMWA 1BR2A 3KINA 1VFZA 2GRYA 2ZFKA 5LT0A 1F9TA 5LT4A 4Y05A 2NCDA 3CNZA 2G1QA 3WPNA 4PFOA 3B6VA 1FMVA 2IEHA 1I6IA 2VB6A 4AP0A 4AS7A 1D0ZA 5LT2A 2OWMA 1GOJA 1VFVA 2ZFJA 1F9VA 2X7CA 1II6A 1T5CA 3LREA 1X88A 2Q2ZA 3L9HA 4E7ZA 2PG2A 1F9UA 2GM1A 2ZFLA 3L1CA 3ZFDA 3BFNA 1MMAA 2Y65A 4A28A 1V8JA 4ZHIA 1MNEA 4PFPA 2UYMA 2X51A 4A50A 1MMDA 4FRZA 2KINA 3T0QA 3H4SA 1RY6A 2X2RA 2FL2A 2VVGA 1BG2A
chains in the Genus database with same CATH superfamily
1MMGA 2FMEA 2V26A 1VFXA 4ANJA 1BR4A 4E7SA 3GBJA 1D1CA 5GSZA 3DC4A 4A5YA 4PJNA 4A14A 4HNAK 3ZCWA 2XAEA 4H1GA 5LT1A 1I5SA 3WRDA 2Y5WA 2Q2YA 3B6UA 1D1AA 4PJJA 3NWNA 1G8XA 4LNUK 1D1BA 4PJMA 3PXNA 1VFWA 3HQDA 1LKXA 2UYIA 3U06A 3KENA 4A1ZA 1N6MA 1Q0BA 4DBQA 4GKPA 2FL6A 1D0YA 3DCBA 2X7DA 4BN2A 4ETPA 5LT3A 1D0XA 3X2TA 1V8KA 1BR1A 1KK7A 1MKJA 1LVKA 5HLEA 2WOGA 3K3BA 4B7BA 2VASA 2MYSA 2X7EA 1CZ7A 4BBGA 1MMNA 3COBA 4DBRA 1F9WA 1VOMA 2ZFMA 3KARA 1SDMA 2HEHA 4PJLA 4A51A 1YRSA 2ZFIA 3K5EA 4GKRA 4UBFA 2XT3A 2FKYA 3ZFCA 4BXNA 2O0AA 3CJOA 4PK4A 4ZCAA 4GKQA 1FMWA 1BR2A 3KINA 1VFZA 2GRYA 2ZFKA 5LT0A 1F9TA 5LT4A 4Y05A 2NCDA 3CNZA 2G1QA 3WPNA 4PFOA 3B6VA 1FMVA 2IEHA 4ETPB 1I6IA 2VB6A 4AP0A 4AS7A 1D0ZA 5LT2A 2OWMA 1GOJA 1VFVA 2ZFJA 1F9VA 2X7CA 1II6A 1T5CA 3LREA 1X88A 2Q2ZA 3L9HA 4E7ZA 2PG2A 1F9UA 2GM1A 2ZFLA 3L1CA 3ZFDA 3BFNA 1MMAA 2Y65A 4A28A 1V8JA 4ZHIA 1MNEA 4PFPA 2UYMA 2X51A 4A50A 1MMDA 4FRZA 2KINA 3T0QA 3H4SA 1RY6A 2X2RA 2FL2A 2VVGA 1BG2A
chains in the Genus database with same CATH topology
1MMGA 2FMEA 2V26A 1VFXA 4ANJA 1BR4A 4E7SA 3GBJA 1D1CA 5GSZA 3DC4A 4A5YA 4PJNA 4A14A 4HNAK 3ZCWA 2XAEA 4H1GA 5LT1A 1I5SA 3WRDA 2Y5WA 2Q2YA 3B6UA 1D1AA 4PJJA 3NWNA 1G8XA 4LNUK 1D1BA 4PJMA 3PXNA 1VFWA 3HQDA 1LKXA 2UYIA 3U06A 3KENA 4A1ZA 1N6MA 1Q0BA 4DBQA 2FL6A 1D0YA 3DCBA 2X7DA 4BN2A 4ETPA 5LT3A 1D0XA 3X2TA 1V8KA 1BR1A 1KK7A 1MKJA 1LVKA 5HLEA 2WOGA 3K3BA 4B7BA 2VASA 2MYSA 2X7EA 1CZ7A 4BBGA 1MMNA 3COBA 4DBRA 1F9WA 1VOMA 2ZFMA 3KARA 1SDMA 2HEHA 4PJLA 4A51A 1YRSA 2ZFIA 3K5EA 4GKRA 4UBFA 2XT3A 2FKYA 3ZFCA 4BXNA 3CJOA 4PK4A 4ZCAA 1FMWA 1BR2A 3KINA 1VFZA 2GRYA 2ZFKA 5LT0A 1F9TA 5LT4A 4Y05A 2NCDA 3CNZA 2G1QA 3WPNA 4PFOA 3B6VA 1FMVA 2IEHA 1I6IA 2VB6A 4AP0A 4AS7A 1D0ZA 5LT2A 2OWMA 1GOJA 1VFVA 2ZFJA 1F9VA 2X7CA 1II6A 1T5CA 3LREA 1X88A 2Q2ZA 3L9HA 4E7ZA 2PG2A 1F9UA 2GM1A 2ZFLA 3L1CA 3ZFDA 3BFNA 1MMAA 2Y65A 4A28A 1V8JA 4ZHIA 1MNEA 4PFPA 2UYMA 2X51A 4A50A 1MMDA 4FRZA 2KINA 3T0QA 3H4SA 1RY6A 2X2RA 2FL2A 2VVGA 1BG2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MMG A;  2FME A;  2V26 A;  1VFX A;  4ANJ A;  1BR4 A;  4E7S A;  3GBJ A;  1D1C A;  5GSZ A;  3DC4 A;  4A5Y A;  4PJN A;  4A14 A;  4HNA K;  3ZCW A;  2XAE A;  4H1G A;  5LT1 A;  1I5S A;  3WRD A;  2Y5W A;  2Q2Y A;  3B6U A;  1D1A A;  4PJJ A;  3NWN A;  1G8X A;  4LNU K;  1D1B A;  4PJM A;  3PXN A;  1VFW A;  3HQD A;  1LKX A;  2UYI A;  3U06 A;  3KEN A;  4A1Z A;  1N6M A;  1Q0B A;  4DBQ A;  2FL6 A;  1D0Y A;  3DCB A;  2X7D A;  4BN2 A;  4ETP A;  5LT3 A;  1D0X A;  3X2T A;  1V8K A;  1BR1 A;  1KK7 A;  1MKJ A;  1LVK A;  5HLE A;  2WOG A;  3K3B A;  4B7B A;  2VAS A;  2MYS A;  2X7E A;  1CZ7 A;  4BBG A;  1MMN A;  3COB A;  4DBR A;  1F9W A;  1VOM A;  2ZFM A;  3KAR A;  1SDM A;  2HEH A;  4PJL A;  4A51 A;  1YRS A;  2ZFI A;  3K5E A;  4GKR A;  4UBF A;  2XT3 A;  2FKY A;  3ZFC A;  4BXN A;  3CJO A;  4PK4 A;  4ZCA A;  1FMW A;  1BR2 A;  3KIN A;  1VFZ A;  2GRY A;  2ZFK A;  5LT0 A;  1F9T A;  5LT4 A;  4Y05 A;  2NCD A;  3CNZ A;  2G1Q A;  3WPN A;  4PFO A;  3B6V A;  1FMV A;  2IEH A;  1I6I A;  2VB6 A;  4AP0 A;  4AS7 A;  1D0Z A;  5LT2 A;  2OWM A;  1GOJ A;  1VFV A;  2ZFJ A;  1F9V A;  2X7C A;  1II6 A;  1T5C A;  3LRE A;  1X88 A;  2Q2Z A;  3L9H A;  4E7Z A;  2PG2 A;  1F9U A;  2GM1 A;  2ZFL A;  3L1C A;  3ZFD A;  3BFN A;  1MMA A;  2Y65 A;  4A28 A;  1V8J A;  4ZHI A;  1MNE A;  4PFP A;  2UYM A;  2X51 A;  4A50 A;  1MMD A;  4FRZ A;  2KIN A;  3T0Q A;  3H4S A;  1RY6 A;  2X2R A;  2FL2 A;  2VVG A;  1BG2 A; 
#chains in the Genus database with same CATH topology
 1MMG A;  2FME A;  2V26 A;  1VFX A;  4ANJ A;  1BR4 A;  4E7S A;  3GBJ A;  1D1C A;  5GSZ A;  3DC4 A;  4A5Y A;  4PJN A;  4A14 A;  4HNA K;  3ZCW A;  2XAE A;  4H1G A;  5LT1 A;  1I5S A;  3WRD A;  2Y5W A;  2Q2Y A;  3B6U A;  1D1A A;  4PJJ A;  3NWN A;  1G8X A;  4LNU K;  1D1B A;  4PJM A;  3PXN A;  1VFW A;  3HQD A;  1LKX A;  2UYI A;  3U06 A;  3KEN A;  4A1Z A;  1N6M A;  1Q0B A;  4DBQ A;  4GKP A;  2FL6 A;  1D0Y A;  3DCB A;  2X7D A;  4BN2 A;  4ETP A;  5LT3 A;  1D0X A;  3X2T A;  1V8K A;  1BR1 A;  1KK7 A;  1MKJ A;  1LVK A;  5HLE A;  2WOG A;  3K3B A;  4B7B A;  2VAS A;  2MYS A;  2X7E A;  1CZ7 A;  4BBG A;  1MMN A;  3COB A;  4DBR A;  1F9W A;  1VOM A;  2ZFM A;  3KAR A;  1SDM A;  2HEH A;  4PJL A;  4A51 A;  1YRS A;  2ZFI A;  3K5E A;  4GKR A;  4UBF A;  2XT3 A;  2FKY A;  3ZFC A;  4BXN A;  2O0A A;  3CJO A;  4PK4 A;  4ZCA A;  4GKQ A;  1FMW A;  1BR2 A;  3KIN A;  1VFZ A;  2GRY A;  2ZFK A;  5LT0 A;  1F9T A;  5LT4 A;  4Y05 A;  2NCD A;  3CNZ A;  2G1Q A;  3WPN A;  4PFO A;  3B6V A;  1FMV A;  2IEH A;  4ETP B;  1I6I A;  2VB6 A;  4AP0 A;  4AS7 A;  1D0Z A;  5LT2 A;  2OWM A;  1GOJ A;  1VFV A;  2ZFJ A;  1F9V A;  2X7C A;  1II6 A;  1T5C A;  3LRE A;  1X88 A;  2Q2Z A;  3L9H A;  4E7Z A;  2PG2 A;  1F9U A;  2GM1 A;  2ZFL A;  3L1C A;  3ZFD A;  3BFN A;  1MMA A;  2Y65 A;  4A28 A;  1V8J A;  4ZHI A;  1MNE A;  4PFP A;  2UYM A;  2X51 A;  4A50 A;  1MMD A;  4FRZ A;  2KIN A;  3T0Q A;  3H4S A;  1RY6 A;  2X2R A;  2FL2 A;  2VVG A;  1BG2 A; 
#chains in the Genus database with same CATH homology
 1MMG A;  2FME A;  2V26 A;  1VFX A;  4ANJ A;  1BR4 A;  4E7S A;  3GBJ A;  1D1C A;  5GSZ A;  3DC4 A;  4A5Y A;  4PJN A;  4A14 A;  4HNA K;  3ZCW A;  2XAE A;  4H1G A;  5LT1 A;  1I5S A;  3WRD A;  2Y5W A;  2Q2Y A;  3B6U A;  1D1A A;  4PJJ A;  3NWN A;  1G8X A;  4LNU K;  1D1B A;  4PJM A;  3PXN A;  1VFW A;  3HQD A;  1LKX A;  2UYI A;  3U06 A;  3KEN A;  4A1Z A;  1N6M A;  1Q0B A;  4DBQ A;  2FL6 A;  1D0Y A;  3DCB A;  2X7D A;  4BN2 A;  4ETP A;  5LT3 A;  1D0X A;  3X2T A;  1V8K A;  1BR1 A;  1KK7 A;  1MKJ A;  1LVK A;  5HLE A;  2WOG A;  3K3B A;  4B7B A;  2VAS A;  2MYS A;  2X7E A;  1CZ7 A;  4BBG A;  1MMN A;  3COB A;  4DBR A;  1F9W A;  1VOM A;  2ZFM A;  3KAR A;  1SDM A;  2HEH A;  4PJL A;  4A51 A;  1YRS A;  2ZFI A;  3K5E A;  4GKR A;  4UBF A;  2XT3 A;  2FKY A;  3ZFC A;  4BXN A;  3CJO A;  4PK4 A;  4ZCA A;  1FMW A;  1BR2 A;  3KIN A;  1VFZ A;  2GRY A;  2ZFK A;  5LT0 A;  1F9T A;  5LT4 A;  4Y05 A;  2NCD A;  3CNZ A;  2G1Q A;  3WPN A;  4PFO A;  3B6V A;  1FMV A;  2IEH A;  1I6I A;  2VB6 A;  4AP0 A;  4AS7 A;  1D0Z A;  5LT2 A;  2OWM A;  1GOJ A;  1VFV A;  2ZFJ A;  1F9V A;  2X7C A;  1II6 A;  1T5C A;  3LRE A;  1X88 A;  2Q2Z A;  3L9H A;  4E7Z A;  2PG2 A;  1F9U A;  2GM1 A;  2ZFL A;  3L1C A;  3ZFD A;  3BFN A;  1MMA A;  2Y65 A;  4A28 A;  1V8J A;  4ZHI A;  1MNE A;  4PFP A;  2UYM A;  2X51 A;  4A50 A;  1MMD A;  4FRZ A;  2KIN A;  3T0Q A;  3H4S A;  1RY6 A;  2X2R A;  2FL2 A;  2VVG A;  1BG2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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