1I5SA

Crystal structure of the kif1a motor domain complexed with mg-adp
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
349
structure length
330
Chain Sequence
ASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEKVSKISLVDLAGSERAKGTRLKEGANINKSLTTLGKVISALAEMDIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Switch-based mechanism of kinesin motors
pubmed doi rcsb
molecule tags Transport protein
source organism Mus musculus
molecule keywords KINESIN-LIKE PROTEIN KIF1A
total genus 104
structure length 330
sequence length 349
ec nomenclature
pdb deposition date 2001-02-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 1i5sA00
2FL2A 2Y5WA 4PK4A 3WPNA 1VOMA 2GM1A 2ZFMA 4ZCAA 4UBFA 1N6MA 3DCBA 3L1CA 5HLEA 4AS7A 3WRDA 4PJLA 1I5SA 3LREA 3BFNA 2UYIA 4GKRA 2Q2YA 4A50A 3B6UA 1T5CA 2UYMA 2X7EA 1VFWA 1D1BA 1VFVA 1BR4A 1BR1A 1G8XA 2VVGA 4PJMA 4PJJA 1FMWA 5LT4A 1SDMA 2ZFJA 2G1QA 1LKXA 2XT3A 2IEHA 2X7DA 4DBQA 4A5YA 1D1CA 2FL6A 2X2RA 4AP0A 4ANJA 3U06A 4BXNA 3K5EA 3COBA 4A1ZA 5LT2A 4ETPA 4A28A 1BR2A 2VB6A 1II6A 2X51A 1CZ7A 5GSZA 1I6IA 1Q0BA 2ZFLA 4DBRA 5LT1A 4FRZA 5LT3A 1KK7A 3B6VA 4E7SA 3PXNA 3NWNA 4Y05A 3T0QA 1BG2A 5LT0A 1V8JA 1D0XA 2KINA 2HEHA 4A51A 2GRYA 2WOGA 4B7BA 4E7ZA 4LNUK 3KARA 1RY6A 1MMDA 1MNEA 4PFPA 1VFXA 1LVKA 2PG2A 1VFZA 1F9TA 3KINA 4PFOA 1D0YA 3ZFDA 1GOJA 4PJNA 2MYSA 2Q2ZA 2FKYA 4A14A 1F9UA 1F9VA 1F9WA 2V26A 1MMNA 3KENA 2NCDA 3CJOA 1V8KA 2XAEA 1YRSA 4HNAK 1MMAA 2X7CA 3ZCWA 3GBJA 3HQDA 3L9HA 3CNZA 3DC4A 1X88A 2OWMA 4BN2A 4BBGA 2FMEA 1MMGA 4H1GA 1D0ZA 3X2TA 1D1AA 2ZFIA 2ZFKA 1FMVA 3ZFCA 4ZHIA 3K3BA 3H4SA 1MKJA 2VASA 2Y65A
chains in the Genus database with same CATH superfamily
2FL2A 2Y5WA 4PK4A 3WPNA 1VOMA 2GM1A 2ZFMA 4ZCAA 4UBFA 1N6MA 3DCBA 3L1CA 5HLEA 4AS7A 3WRDA 4PJLA 1I5SA 3LREA 3BFNA 2UYIA 4GKRA 2Q2YA 4A50A 3B6UA 1T5CA 2UYMA 2X7EA 1VFWA 1D1BA 1VFVA 1BR4A 1BR1A 1G8XA 2VVGA 4GKPA 4PJJA 1FMWA 4PJMA 5LT4A 1SDMA 2ZFJA 2G1QA 1LKXA 2XT3A 2IEHA 2X7DA 4DBQA 4A5YA 1D1CA 2FL6A 2X2RA 4AP0A 4ANJA 3U06A 4BXNA 3K5EA 3COBA 4A1ZA 5LT2A 4ETPA 4A28A 1BR2A 2VB6A 1II6A 2X51A 4ETPB 1CZ7A 5GSZA 1I6IA 1Q0BA 2ZFLA 4DBRA 5LT1A 4FRZA 5LT3A 1KK7A 3B6VA 4E7SA 3PXNA 3NWNA 4Y05A 3T0QA 1BG2A 5LT0A 1V8JA 1D0XA 2KINA 2HEHA 4A51A 2GRYA 2WOGA 4B7BA 4E7ZA 4LNUK 3KARA 1RY6A 1MMDA 1MNEA 4PFPA 1VFXA 2O0AA 1LVKA 2PG2A 1VFZA 1F9TA 3KINA 4PFOA 1D0YA 3ZFDA 1GOJA 4PJNA 2MYSA 2Q2ZA 2FKYA 4A14A 1F9UA 1F9VA 1F9WA 2V26A 1MMNA 3KENA 2NCDA 3CJOA 1V8KA 2XAEA 1YRSA 4HNAK 1MMAA 2X7CA 3ZCWA 3GBJA 3HQDA 3L9HA 3CNZA 3DC4A 1X88A 2OWMA 4BN2A 4BBGA 2FMEA 1MMGA 4H1GA 1D0ZA 3X2TA 1D1AA 2ZFIA 2ZFKA 1FMVA 3ZFCA 4ZHIA 3K3BA 3H4SA 1MKJA 2VASA 2Y65A 4GKQA
chains in the Genus database with same CATH topology
2FL2A 2Y5WA 4PK4A 3WPNA 1VOMA 2GM1A 2ZFMA 4ZCAA 4UBFA 1N6MA 3DCBA 3L1CA 5HLEA 4AS7A 3WRDA 4PJLA 1I5SA 3LREA 3BFNA 2UYIA 4GKRA 2Q2YA 4A50A 3B6UA 1T5CA 2UYMA 2X7EA 1VFWA 1D1BA 1VFVA 1BR4A 1BR1A 1G8XA 2VVGA 4PJMA 4PJJA 1FMWA 5LT4A 1SDMA 2ZFJA 2G1QA 1LKXA 2XT3A 2IEHA 2X7DA 4DBQA 4A5YA 1D1CA 2FL6A 2X2RA 4AP0A 4ANJA 3U06A 4BXNA 3K5EA 3COBA 4A1ZA 5LT2A 4ETPA 4A28A 1BR2A 2VB6A 1II6A 2X51A 1CZ7A 5GSZA 1I6IA 1Q0BA 2ZFLA 4DBRA 5LT1A 4FRZA 5LT3A 1KK7A 3B6VA 4E7SA 3PXNA 3NWNA 4Y05A 3T0QA 1BG2A 5LT0A 1V8JA 1D0XA 2KINA 2HEHA 4A51A 2GRYA 2WOGA 4B7BA 4E7ZA 4LNUK 3KARA 1RY6A 1MMDA 1MNEA 4PFPA 1VFXA 1LVKA 2PG2A 1VFZA 1F9TA 3KINA 4PFOA 1D0YA 3ZFDA 1GOJA 4PJNA 2MYSA 2Q2ZA 2FKYA 4A14A 1F9UA 1F9VA 1F9WA 2V26A 1MMNA 3KENA 2NCDA 3CJOA 1V8KA 2XAEA 1YRSA 4HNAK 1MMAA 2X7CA 3ZCWA 3GBJA 3HQDA 3L9HA 3CNZA 3DC4A 1X88A 2OWMA 4BN2A 4BBGA 2FMEA 1MMGA 4H1GA 1D0ZA 3X2TA 1D1AA 2ZFIA 2ZFKA 1FMVA 3ZFCA 4ZHIA 3K3BA 3H4SA 1MKJA 2VASA 2Y65A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FL2 A;  2Y5W A;  4PK4 A;  3WPN A;  1VOM A;  2GM1 A;  2ZFM A;  4ZCA A;  4UBF A;  1N6M A;  3DCB A;  3L1C A;  5HLE A;  4AS7 A;  3WRD A;  4PJL A;  1I5S A;  3LRE A;  3BFN A;  2UYI A;  4GKR A;  2Q2Y A;  4A50 A;  3B6U A;  1T5C A;  2UYM A;  2X7E A;  1VFW A;  1D1B A;  1VFV A;  1BR4 A;  1BR1 A;  1G8X A;  2VVG A;  4PJM A;  4PJJ A;  1FMW A;  5LT4 A;  1SDM A;  2ZFJ A;  2G1Q A;  1LKX A;  2XT3 A;  2IEH A;  2X7D A;  4DBQ A;  4A5Y A;  1D1C A;  2FL6 A;  2X2R A;  4AP0 A;  4ANJ A;  3U06 A;  4BXN A;  3K5E A;  3COB A;  4A1Z A;  5LT2 A;  4ETP A;  4A28 A;  1BR2 A;  2VB6 A;  1II6 A;  2X51 A;  1CZ7 A;  5GSZ A;  1I6I A;  1Q0B A;  2ZFL A;  4DBR A;  5LT1 A;  4FRZ A;  5LT3 A;  1KK7 A;  3B6V A;  4E7S A;  3PXN A;  3NWN A;  4Y05 A;  3T0Q A;  1BG2 A;  5LT0 A;  1V8J A;  1D0X A;  2KIN A;  2HEH A;  4A51 A;  2GRY A;  2WOG A;  4B7B A;  4E7Z A;  4LNU K;  3KAR A;  1RY6 A;  1MMD A;  1MNE A;  4PFP A;  1VFX A;  1LVK A;  2PG2 A;  1VFZ A;  1F9T A;  3KIN A;  4PFO A;  1D0Y A;  3ZFD A;  1GOJ A;  4PJN A;  2MYS A;  2Q2Z A;  2FKY A;  4A14 A;  1F9U A;  1F9V A;  1F9W A;  2V26 A;  1MMN A;  3KEN A;  2NCD A;  3CJO A;  1V8K A;  2XAE A;  1YRS A;  4HNA K;  1MMA A;  2X7C A;  3ZCW A;  3GBJ A;  3HQD A;  3L9H A;  3CNZ A;  3DC4 A;  1X88 A;  2OWM A;  4BN2 A;  4BBG A;  2FME A;  1MMG A;  4H1G A;  1D0Z A;  3X2T A;  1D1A A;  2ZFI A;  2ZFK A;  1FMV A;  3ZFC A;  4ZHI A;  3K3B A;  3H4S A;  1MKJ A;  2VAS A;  2Y65 A; 
#chains in the Genus database with same CATH topology
 2FL2 A;  2Y5W A;  4PK4 A;  3WPN A;  1VOM A;  2GM1 A;  2ZFM A;  4ZCA A;  4UBF A;  1N6M A;  3DCB A;  3L1C A;  5HLE A;  4AS7 A;  3WRD A;  4PJL A;  1I5S A;  3LRE A;  3BFN A;  2UYI A;  4GKR A;  2Q2Y A;  4A50 A;  3B6U A;  1T5C A;  2UYM A;  2X7E A;  1VFW A;  1D1B A;  1VFV A;  1BR4 A;  1BR1 A;  1G8X A;  2VVG A;  4GKP A;  4PJJ A;  1FMW A;  4PJM A;  5LT4 A;  1SDM A;  2ZFJ A;  2G1Q A;  1LKX A;  2XT3 A;  2IEH A;  2X7D A;  4DBQ A;  4A5Y A;  1D1C A;  2FL6 A;  2X2R A;  4AP0 A;  4ANJ A;  3U06 A;  4BXN A;  3K5E A;  3COB A;  4A1Z A;  5LT2 A;  4ETP A;  4A28 A;  1BR2 A;  2VB6 A;  1II6 A;  2X51 A;  4ETP B;  1CZ7 A;  5GSZ A;  1I6I A;  1Q0B A;  2ZFL A;  4DBR A;  5LT1 A;  4FRZ A;  5LT3 A;  1KK7 A;  3B6V A;  4E7S A;  3PXN A;  3NWN A;  4Y05 A;  3T0Q A;  1BG2 A;  5LT0 A;  1V8J A;  1D0X A;  2KIN A;  2HEH A;  4A51 A;  2GRY A;  2WOG A;  4B7B A;  4E7Z A;  4LNU K;  3KAR A;  1RY6 A;  1MMD A;  1MNE A;  4PFP A;  1VFX A;  2O0A A;  1LVK A;  2PG2 A;  1VFZ A;  1F9T A;  3KIN A;  4PFO A;  1D0Y A;  3ZFD A;  1GOJ A;  4PJN A;  2MYS A;  2Q2Z A;  2FKY A;  4A14 A;  1F9U A;  1F9V A;  1F9W A;  2V26 A;  1MMN A;  3KEN A;  2NCD A;  3CJO A;  1V8K A;  2XAE A;  1YRS A;  4HNA K;  1MMA A;  2X7C A;  3ZCW A;  3GBJ A;  3HQD A;  3L9H A;  3CNZ A;  3DC4 A;  1X88 A;  2OWM A;  4BN2 A;  4BBG A;  2FME A;  1MMG A;  4H1G A;  1D0Z A;  3X2T A;  1D1A A;  2ZFI A;  2ZFK A;  1FMV A;  3ZFC A;  4ZHI A;  3K3B A;  3H4S A;  1MKJ A;  2VAS A;  2Y65 A;  4GKQ A; 
#chains in the Genus database with same CATH homology
 2FL2 A;  2Y5W A;  4PK4 A;  3WPN A;  1VOM A;  2GM1 A;  2ZFM A;  4ZCA A;  4UBF A;  1N6M A;  3DCB A;  3L1C A;  5HLE A;  4AS7 A;  3WRD A;  4PJL A;  1I5S A;  3LRE A;  3BFN A;  2UYI A;  4GKR A;  2Q2Y A;  4A50 A;  3B6U A;  1T5C A;  2UYM A;  2X7E A;  1VFW A;  1D1B A;  1VFV A;  1BR4 A;  1BR1 A;  1G8X A;  2VVG A;  4PJM A;  4PJJ A;  1FMW A;  5LT4 A;  1SDM A;  2ZFJ A;  2G1Q A;  1LKX A;  2XT3 A;  2IEH A;  2X7D A;  4DBQ A;  4A5Y A;  1D1C A;  2FL6 A;  2X2R A;  4AP0 A;  4ANJ A;  3U06 A;  4BXN A;  3K5E A;  3COB A;  4A1Z A;  5LT2 A;  4ETP A;  4A28 A;  1BR2 A;  2VB6 A;  1II6 A;  2X51 A;  1CZ7 A;  5GSZ A;  1I6I A;  1Q0B A;  2ZFL A;  4DBR A;  5LT1 A;  4FRZ A;  5LT3 A;  1KK7 A;  3B6V A;  4E7S A;  3PXN A;  3NWN A;  4Y05 A;  3T0Q A;  1BG2 A;  5LT0 A;  1V8J A;  1D0X A;  2KIN A;  2HEH A;  4A51 A;  2GRY A;  2WOG A;  4B7B A;  4E7Z A;  4LNU K;  3KAR A;  1RY6 A;  1MMD A;  1MNE A;  4PFP A;  1VFX A;  1LVK A;  2PG2 A;  1VFZ A;  1F9T A;  3KIN A;  4PFO A;  1D0Y A;  3ZFD A;  1GOJ A;  4PJN A;  2MYS A;  2Q2Z A;  2FKY A;  4A14 A;  1F9U A;  1F9V A;  1F9W A;  2V26 A;  1MMN A;  3KEN A;  2NCD A;  3CJO A;  1V8K A;  2XAE A;  1YRS A;  4HNA K;  1MMA A;  2X7C A;  3ZCW A;  3GBJ A;  3HQD A;  3L9H A;  3CNZ A;  3DC4 A;  1X88 A;  2OWM A;  4BN2 A;  4BBG A;  2FME A;  1MMG A;  4H1G A;  1D0Z A;  3X2T A;  1D1A A;  2ZFI A;  2ZFK A;  1FMV A;  3ZFC A;  4ZHI A;  3K3B A;  3H4S A;  1MKJ A;  2VAS A;  2Y65 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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