2GRYA

Crystal structure of the human kif2 motor domain in complex with adp
Total Genus 114
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
355
structure length
327
Chain Sequence
EIMCMIRDFRGSLDYRPLPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERDRQTRLEGAEINKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of the human KIF2 motor domain in complex with ADP
rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords Kinesin-like protein KIF2
total genus 114
structure length 327
sequence length 355
ec nomenclature
pdb deposition date 2006-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 2gryA00
1D0YA 4PFPA 3B6UA 5GSZA 4ETPA 4GKRA 3B6VA 5LT0A 4BBGA 1Q0BA 2X7DA 2Q2ZA 5LT4A 3CJOA 1VOMA 2FL2A 2FKYA 2KINA 4ZCAA 3PXNA 1GOJA 1MKJA 3X2TA 2X51A 1VFWA 3K5EA 2OWMA 2ZFJA 1G8XA 2UYMA 1KK7A 2X7CA 1F9TA 4PK4A 4AS7A 4BXNA 2IEHA 2VVGA 1N6MA 2G1QA 4DBQA 1D0XA 1LKXA 4Y05A 2FMEA 4UBFA 4A5YA 2XAEA 2VASA 1F9UA 3COBA 4PJJA 4ANJA 1MMAA 4PJMA 3HQDA 4PJLA 1VFVA 3LREA 2V26A 1D1AA 1V8KA 2PG2A 5LT2A 1X88A 2Y65A 2X7EA 3BFNA 3ZFDA 4B7BA 4E7SA 2VB6A 1RY6A 1MMNA 2GRYA 5LT1A 3CNZA 3L9HA 1BR4A 4A28A 1VFZA 3WPNA 1LVKA 1I5SA 4HNAK 3L1CA 4H1GA 1SDMA 3U06A 2FL6A 1BR2A 1VFXA 3KINA 3K3BA 4A14A 1D0ZA 2Q2YA 2NCDA 4AP0A 1F9WA 5HLEA 1MNEA 4A1ZA 2MYSA 1V8JA 2HEHA 4FRZA 2GM1A 1CZ7A 1BR1A 2Y5WA 2ZFIA 3KARA 1BG2A 2ZFKA 1D1CA 4LNUK 3NWNA 4BN2A 2WOGA 3DCBA 1MMDA 3ZCWA 3ZFCA 4A51A 3H4SA 4DBRA 1FMVA 5LT3A 4ZHIA 4E7ZA 2XT3A 2UYIA 1F9VA 4PFOA 1I6IA 2X2RA 3WRDA 4A50A 1YRSA 3GBJA 3T0QA 2ZFLA 1MMGA 2ZFMA 3DC4A 1D1BA 1II6A 1T5CA 1FMWA 4PJNA 3KENA
chains in the Genus database with same CATH superfamily
1D0YA 4PFPA 3B6UA 5GSZA 4ETPA 4GKRA 3B6VA 5LT0A 4BBGA 1Q0BA 2X7DA 2Q2ZA 5LT4A 3CJOA 1VOMA 2FL2A 2FKYA 2KINA 4ZCAA 3PXNA 1GOJA 1MKJA 3X2TA 2X51A 1VFWA 3K5EA 2OWMA 2ZFJA 1G8XA 2UYMA 1KK7A 2X7CA 1F9TA 4PK4A 4AS7A 4BXNA 2IEHA 2VVGA 1N6MA 2G1QA 4DBQA 1D0XA 1LKXA 4Y05A 2FMEA 4GKPA 4UBFA 4A5YA 2XAEA 2VASA 1F9UA 3COBA 4PJJA 4ANJA 1MMAA 4PJMA 3HQDA 4PJLA 1VFVA 3LREA 2V26A 1D1AA 1V8KA 2PG2A 5LT2A 1X88A 2Y65A 2X7EA 3BFNA 3ZFDA 4B7BA 4E7SA 2VB6A 1RY6A 1MMNA 2GRYA 5LT1A 3CNZA 3L9HA 1BR4A 4A28A 1VFZA 3WPNA 1LVKA 1I5SA 4HNAK 3L1CA 4H1GA 1SDMA 3U06A 2FL6A 1BR2A 1VFXA 3KINA 3K3BA 4A14A 1D0ZA 2Q2YA 2NCDA 4AP0A 1F9WA 5HLEA 1MNEA 4A1ZA 2MYSA 1V8JA 2HEHA 4FRZA 2GM1A 1CZ7A 1BR1A 2Y5WA 2O0AA 2ZFIA 3KARA 1BG2A 2ZFKA 1D1CA 4LNUK 3NWNA 4BN2A 2WOGA 3DCBA 1MMDA 3ZCWA 3ZFCA 4A51A 3H4SA 4DBRA 4ETPB 1FMVA 5LT3A 4ZHIA 4E7ZA 2XT3A 4GKQA 2UYIA 1F9VA 4PFOA 1I6IA 2X2RA 3WRDA 4A50A 1YRSA 3GBJA 3T0QA 2ZFLA 1MMGA 2ZFMA 3DC4A 1D1BA 1II6A 1T5CA 1FMWA 4PJNA 3KENA
chains in the Genus database with same CATH topology
1D0YA 4PFPA 3B6UA 5GSZA 4ETPA 4GKRA 3B6VA 5LT0A 4BBGA 1Q0BA 2X7DA 2Q2ZA 5LT4A 3CJOA 1VOMA 2FL2A 2FKYA 2KINA 4ZCAA 3PXNA 1GOJA 1MKJA 3X2TA 2X51A 1VFWA 3K5EA 2OWMA 2ZFJA 1G8XA 2UYMA 1KK7A 2X7CA 1F9TA 4PK4A 4AS7A 4BXNA 2IEHA 2VVGA 1N6MA 2G1QA 4DBQA 1D0XA 1LKXA 4Y05A 2FMEA 4UBFA 4A5YA 2XAEA 2VASA 1F9UA 3COBA 4PJJA 4ANJA 1MMAA 4PJMA 3HQDA 4PJLA 1VFVA 3LREA 2V26A 1D1AA 1V8KA 2PG2A 5LT2A 1X88A 2Y65A 2X7EA 3BFNA 3ZFDA 4B7BA 4E7SA 2VB6A 1RY6A 1MMNA 2GRYA 5LT1A 3CNZA 3L9HA 1BR4A 4A28A 1VFZA 3WPNA 1LVKA 1I5SA 4HNAK 3L1CA 4H1GA 1SDMA 3U06A 2FL6A 1BR2A 1VFXA 3KINA 3K3BA 4A14A 1D0ZA 2Q2YA 2NCDA 4AP0A 1F9WA 5HLEA 1MNEA 4A1ZA 2MYSA 1V8JA 2HEHA 4FRZA 2GM1A 1CZ7A 1BR1A 2Y5WA 2ZFIA 3KARA 1BG2A 2ZFKA 1D1CA 4LNUK 3NWNA 4BN2A 2WOGA 3DCBA 1MMDA 3ZCWA 3ZFCA 4A51A 3H4SA 4DBRA 1FMVA 5LT3A 4ZHIA 4E7ZA 2XT3A 2UYIA 1F9VA 4PFOA 1I6IA 2X2RA 3WRDA 4A50A 1YRSA 3GBJA 3T0QA 2ZFLA 1MMGA 2ZFMA 3DC4A 1D1BA 1II6A 1T5CA 1FMWA 4PJNA 3KENA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1D0Y A;  4PFP A;  3B6U A;  5GSZ A;  4ETP A;  4GKR A;  3B6V A;  5LT0 A;  4BBG A;  1Q0B A;  2X7D A;  2Q2Z A;  5LT4 A;  3CJO A;  1VOM A;  2FL2 A;  2FKY A;  2KIN A;  4ZCA A;  3PXN A;  1GOJ A;  1MKJ A;  3X2T A;  2X51 A;  1VFW A;  3K5E A;  2OWM A;  2ZFJ A;  1G8X A;  2UYM A;  1KK7 A;  2X7C A;  1F9T A;  4PK4 A;  4AS7 A;  4BXN A;  2IEH A;  2VVG A;  1N6M A;  2G1Q A;  4DBQ A;  1D0X A;  1LKX A;  4Y05 A;  2FME A;  4UBF A;  4A5Y A;  2XAE A;  2VAS A;  1F9U A;  3COB A;  4PJJ A;  4ANJ A;  1MMA A;  4PJM A;  3HQD A;  4PJL A;  1VFV A;  3LRE A;  2V26 A;  1D1A A;  1V8K A;  2PG2 A;  5LT2 A;  1X88 A;  2Y65 A;  2X7E A;  3BFN A;  3ZFD A;  4B7B A;  4E7S A;  2VB6 A;  1RY6 A;  1MMN A;  2GRY A;  5LT1 A;  3CNZ A;  3L9H A;  1BR4 A;  4A28 A;  1VFZ A;  3WPN A;  1LVK A;  1I5S A;  4HNA K;  3L1C A;  4H1G A;  1SDM A;  3U06 A;  2FL6 A;  1BR2 A;  1VFX A;  3KIN A;  3K3B A;  4A14 A;  1D0Z A;  2Q2Y A;  2NCD A;  4AP0 A;  1F9W A;  5HLE A;  1MNE A;  4A1Z A;  2MYS A;  1V8J A;  2HEH A;  4FRZ A;  2GM1 A;  1CZ7 A;  1BR1 A;  2Y5W A;  2ZFI A;  3KAR A;  1BG2 A;  2ZFK A;  1D1C A;  4LNU K;  3NWN A;  4BN2 A;  2WOG A;  3DCB A;  1MMD A;  3ZCW A;  3ZFC A;  4A51 A;  3H4S A;  4DBR A;  1FMV A;  5LT3 A;  4ZHI A;  4E7Z A;  2XT3 A;  2UYI A;  1F9V A;  4PFO A;  1I6I A;  2X2R A;  3WRD A;  4A50 A;  1YRS A;  3GBJ A;  3T0Q A;  2ZFL A;  1MMG A;  2ZFM A;  3DC4 A;  1D1B A;  1II6 A;  1T5C A;  1FMW A;  4PJN A;  3KEN A; 
#chains in the Genus database with same CATH topology
 1D0Y A;  4PFP A;  3B6U A;  5GSZ A;  4ETP A;  4GKR A;  3B6V A;  5LT0 A;  4BBG A;  1Q0B A;  2X7D A;  2Q2Z A;  5LT4 A;  3CJO A;  1VOM A;  2FL2 A;  2FKY A;  2KIN A;  4ZCA A;  3PXN A;  1GOJ A;  1MKJ A;  3X2T A;  2X51 A;  1VFW A;  3K5E A;  2OWM A;  2ZFJ A;  1G8X A;  2UYM A;  1KK7 A;  2X7C A;  1F9T A;  4PK4 A;  4AS7 A;  4BXN A;  2IEH A;  2VVG A;  1N6M A;  2G1Q A;  4DBQ A;  1D0X A;  1LKX A;  4Y05 A;  2FME A;  4GKP A;  4UBF A;  4A5Y A;  2XAE A;  2VAS A;  1F9U A;  3COB A;  4PJJ A;  4ANJ A;  1MMA A;  4PJM A;  3HQD A;  4PJL A;  1VFV A;  3LRE A;  2V26 A;  1D1A A;  1V8K A;  2PG2 A;  5LT2 A;  1X88 A;  2Y65 A;  2X7E A;  3BFN A;  3ZFD A;  4B7B A;  4E7S A;  2VB6 A;  1RY6 A;  1MMN A;  2GRY A;  5LT1 A;  3CNZ A;  3L9H A;  1BR4 A;  4A28 A;  1VFZ A;  3WPN A;  1LVK A;  1I5S A;  4HNA K;  3L1C A;  4H1G A;  1SDM A;  3U06 A;  2FL6 A;  1BR2 A;  1VFX A;  3KIN A;  3K3B A;  4A14 A;  1D0Z A;  2Q2Y A;  2NCD A;  4AP0 A;  1F9W A;  5HLE A;  1MNE A;  4A1Z A;  2MYS A;  1V8J A;  2HEH A;  4FRZ A;  2GM1 A;  1CZ7 A;  1BR1 A;  2Y5W A;  2O0A A;  2ZFI A;  3KAR A;  1BG2 A;  2ZFK A;  1D1C A;  4LNU K;  3NWN A;  4BN2 A;  2WOG A;  3DCB A;  1MMD A;  3ZCW A;  3ZFC A;  4A51 A;  3H4S A;  4DBR A;  4ETP B;  1FMV A;  5LT3 A;  4ZHI A;  4E7Z A;  2XT3 A;  4GKQ A;  2UYI A;  1F9V A;  4PFO A;  1I6I A;  2X2R A;  3WRD A;  4A50 A;  1YRS A;  3GBJ A;  3T0Q A;  2ZFL A;  1MMG A;  2ZFM A;  3DC4 A;  1D1B A;  1II6 A;  1T5C A;  1FMW A;  4PJN A;  3KEN A; 
#chains in the Genus database with same CATH homology
 1D0Y A;  4PFP A;  3B6U A;  5GSZ A;  4ETP A;  4GKR A;  3B6V A;  5LT0 A;  4BBG A;  1Q0B A;  2X7D A;  2Q2Z A;  5LT4 A;  3CJO A;  1VOM A;  2FL2 A;  2FKY A;  2KIN A;  4ZCA A;  3PXN A;  1GOJ A;  1MKJ A;  3X2T A;  2X51 A;  1VFW A;  3K5E A;  2OWM A;  2ZFJ A;  1G8X A;  2UYM A;  1KK7 A;  2X7C A;  1F9T A;  4PK4 A;  4AS7 A;  4BXN A;  2IEH A;  2VVG A;  1N6M A;  2G1Q A;  4DBQ A;  1D0X A;  1LKX A;  4Y05 A;  2FME A;  4UBF A;  4A5Y A;  2XAE A;  2VAS A;  1F9U A;  3COB A;  4PJJ A;  4ANJ A;  1MMA A;  4PJM A;  3HQD A;  4PJL A;  1VFV A;  3LRE A;  2V26 A;  1D1A A;  1V8K A;  2PG2 A;  5LT2 A;  1X88 A;  2Y65 A;  2X7E A;  3BFN A;  3ZFD A;  4B7B A;  4E7S A;  2VB6 A;  1RY6 A;  1MMN A;  2GRY A;  5LT1 A;  3CNZ A;  3L9H A;  1BR4 A;  4A28 A;  1VFZ A;  3WPN A;  1LVK A;  1I5S A;  4HNA K;  3L1C A;  4H1G A;  1SDM A;  3U06 A;  2FL6 A;  1BR2 A;  1VFX A;  3KIN A;  3K3B A;  4A14 A;  1D0Z A;  2Q2Y A;  2NCD A;  4AP0 A;  1F9W A;  5HLE A;  1MNE A;  4A1Z A;  2MYS A;  1V8J A;  2HEH A;  4FRZ A;  2GM1 A;  1CZ7 A;  1BR1 A;  2Y5W A;  2ZFI A;  3KAR A;  1BG2 A;  2ZFK A;  1D1C A;  4LNU K;  3NWN A;  4BN2 A;  2WOG A;  3DCB A;  1MMD A;  3ZCW A;  3ZFC A;  4A51 A;  3H4S A;  4DBR A;  1FMV A;  5LT3 A;  4ZHI A;  4E7Z A;  2XT3 A;  2UYI A;  1F9V A;  4PFO A;  1I6I A;  2X2R A;  3WRD A;  4A50 A;  1YRS A;  3GBJ A;  3T0Q A;  2ZFL A;  1MMG A;  2ZFM A;  3DC4 A;  1D1B A;  1II6 A;  1T5C A;  1FMW A;  4PJN A;  3KEN A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...