2HEH | Genus

Total Genus 107

Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	107
sequence length	359
structure length	324
Chain Sequence	NWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGKGIYAMASRDVFLLKNQPCYRKLGLEVYVTFFEIYNGKLFDLLNKKAKLRVLEDGKQQVQVVGLQEHLVNSADDVIKMIDMGSACRNSSRSHACFQIILRAKGRMHGKFSLVDLAGNEGAEINKSLLALKECIRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIATISPGISSCEYTLNTLRYADRVKE

Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__6902893932063794__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__6902893932063794__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/2HEH/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__6902893932063794__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"6902893932063794","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/2HEH/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__6902893932063794__ ready

script 1 started

platformSpeed = 8

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Structural genomics, structural protein
source organism	Homo sapiens
publication title	Crystal structure of the kif2c motor domain rcsb
molecule keywords	KIF2C protein
total genus	107
structure length	324
sequence length	359
ec nomenclature
pdb deposition date	2006-06-21

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00225	Kinesin	Kinesin motor domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.850.10	Alpha Beta	3-Layer(aba) Sandwich	Kinesin	Kinesin motor domain	2hehA00

3GBJA 2VVGA 1D1BA 2G1QA 2GRYA 4DBQA 1V8JA 3HQDA 2ZFMA 3WPNA 4LNUK 4ANJA 4PK4A 2X51A 1II6A 1MMNA 2ZFIA 4HNAK 1CZ7A 4BN2A 4PFPA 3KENA 1YRSA 4FRZA 3ZCWA 3ZFDA 4E7SA 2XAEA 2VASA 2ZFLA 1D0XA 4A5YA 5LT4A 5LT3A 1MMDA 4ZHIA 2OWMA 4E7ZA 3K5EA 5GSZA 1F9VA 1VOMA 1N6MA 2UYMA 3CNZA 3KINA 2MYSA 4PJLA 4UBFA 3BFNA 3ZFCA 1V8KA 3DC4A 1F9UA 2ZFJA 1GOJA 4PFOA 2V26A 2IEHA 3B6UA 4BBGA 1VFZA 3CJOA 3H4SA 3NWNA 1MKJA 4A50A 1VFVA 2WOGA 4Y05A 3B6VA 3X2TA 4PJNA 4A14A 2GM1A 1F9WA 4ZCAA 2Y65A 1T5CA 1BR2A 3WRDA 3U06A 1LVKA 2KINA 2X7CA 1VFWA 4AP0A 4B7BA 3L1CA 1G8XA 3L9HA 1VFXA 4GKRA 2HEHA 3K3BA 4AS7A 2X2RA 3T0QA 2FMEA 1MMGA 5LT1A 1D0YA 4BXNA 1FMVA 5LT2A 1LKXA 1D1AA 1MMAA 2PG2A 1I5SA 4A51A 3DCBA 2NCDA 1I6IA 3COBA 1SDMA 1MNEA 2XT3A 4PJJA 4DBRA 4A1ZA 2FL6A 2ZFKA 5LT0A 4PJMA 1D0ZA 1RY6A 2VB6A 2X7EA 3LREA 4ETPA 2UYIA 3PXNA 1X88A 2X7DA 1D1CA 4H1GA 2Q2ZA 1F9TA 5HLEA 2FL2A 2Q2YA 1KK7A 1BG2A 2FKYA 4A28A 1BR4A 1BR1A 1Q0BA 1FMWA 2Y5WA 3KARA
chains in the Genus database with same CATH superfamily

3GBJA 2VVGA 1D1BA 2G1QA 2GRYA 4DBQA 1V8JA 3HQDA 2ZFMA 3WPNA 4LNUK 4ANJA 4PK4A 2X51A 1II6A 1MMNA 2ZFIA 4HNAK 1CZ7A 4BN2A 4PFPA 3KENA 2O0AA 1YRSA 4FRZA 3ZCWA 3ZFDA 4E7SA 2XAEA 2VASA 2ZFLA 1D0XA 4A5YA 5LT4A 5LT3A 1MMDA 4ZHIA 2OWMA 4E7ZA 3K5EA 5GSZA 1F9VA 1VOMA 1N6MA 2UYMA 3CNZA 3KINA 2MYSA 4PJLA 4UBFA 3BFNA 3ZFCA 1V8KA 3DC4A 1F9UA 2ZFJA 1GOJA 4PFOA 2V26A 2IEHA 3B6UA 4BBGA 1VFZA 3CJOA 3H4SA 3NWNA 1MKJA 4A50A 4GKPA 1VFVA 2WOGA 4Y05A 3B6VA 3X2TA 4PJNA 4A14A 2GM1A 1F9WA 4ZCAA 2Y65A 1T5CA 1BR2A 3WRDA 3U06A 1LVKA 2KINA 2X7CA 1VFWA 4AP0A 4B7BA 3L1CA 1G8XA 3L9HA 4ETPB 1VFXA 4GKRA 2HEHA 3K3BA 4AS7A 2X2RA 3T0QA 2FMEA 1MMGA 5LT1A 1D0YA 4BXNA 1FMVA 5LT2A 1LKXA 1D1AA 1MMAA 2PG2A 1I5SA 4A51A 3DCBA 2NCDA 1I6IA 3COBA 1SDMA 1MNEA 2XT3A 4PJJA 4DBRA 4A1ZA 2FL6A 2ZFKA 5LT0A 4PJMA 1D0ZA 1RY6A 2VB6A 2X7EA 3LREA 4GKQA 4ETPA 2UYIA 3PXNA 1X88A 2X7DA 1D1CA 4H1GA 2Q2ZA 1F9TA 5HLEA 2FL2A 2Q2YA 1KK7A 1BG2A 2FKYA 4A28A 1BR4A 1BR1A 1Q0BA 1FMWA 2Y5WA 3KARA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3GBJ A;  2VVG A;  1D1B A;  2G1Q A;  2GRY A;  4DBQ A;  1V8J A;  3HQD A;  2ZFM A;  3WPN A;  4LNU K;  4ANJ A;  4PK4 A;  2X51 A;  1II6 A;  1MMN A;  2ZFI A;  4HNA K;  1CZ7 A;  4BN2 A;  4PFP A;  3KEN A;  1YRS A;  4FRZ A;  3ZCW A;  3ZFD A;  4E7S A;  2XAE A;  2VAS A;  2ZFL A;  1D0X A;  4A5Y A;  5LT4 A;  5LT3 A;  1MMD A;  4ZHI A;  2OWM A;  4E7Z A;  3K5E A;  5GSZ A;  1F9V A;  1VOM A;  1N6M A;  2UYM A;  3CNZ A;  3KIN A;  2MYS A;  4PJL A;  4UBF A;  3BFN A;  3ZFC A;  1V8K A;  3DC4 A;  1F9U A;  2ZFJ A;  1GOJ A;  4PFO A;  2V26 A;  2IEH A;  3B6U A;  4BBG A;  1VFZ A;  3CJO A;  3H4S A;  3NWN A;  1MKJ A;  4A50 A;  1VFV A;  2WOG A;  4Y05 A;  3B6V A;  3X2T A;  4PJN A;  4A14 A;  2GM1 A;  1F9W A;  4ZCA A;  2Y65 A;  1T5C A;  1BR2 A;  3WRD A;  3U06 A;  1LVK A;  2KIN A;  2X7C A;  1VFW A;  4AP0 A;  4B7B A;  3L1C A;  1G8X A;  3L9H A;  1VFX A;  4GKR A;  2HEH A;  3K3B A;  4AS7 A;  2X2R A;  3T0Q A;  2FME A;  1MMG A;  5LT1 A;  1D0Y A;  4BXN A;  1FMV A;  5LT2 A;  1LKX A;  1D1A A;  1MMA A;  2PG2 A;  1I5S A;  4A51 A;  3DCB A;  2NCD A;  1I6I A;  3COB A;  1SDM A;  1MNE A;  2XT3 A;  4PJJ A;  4DBR A;  4A1Z A;  2FL6 A;  2ZFK A;  5LT0 A;  4PJM A;  1D0Z A;  1RY6 A;  2VB6 A;  2X7E A;  3LRE A;  4ETP A;  2UYI A;  3PXN A;  1X88 A;  2X7D A;  1D1C A;  4H1G A;  2Q2Z A;  1F9T A;  5HLE A;  2FL2 A;  2Q2Y A;  1KK7 A;  1BG2 A;  2FKY A;  4A28 A;  1BR4 A;  1BR1 A;  1Q0B A;  1FMW A;  2Y5W A;  3KAR A; 
#chains in the Genus database with same CATH topology
 3GBJ A;  2VVG A;  1D1B A;  2G1Q A;  2GRY A;  4DBQ A;  1V8J A;  3HQD A;  2ZFM A;  3WPN A;  4LNU K;  4ANJ A;  4PK4 A;  2X51 A;  1II6 A;  1MMN A;  2ZFI A;  4HNA K;  1CZ7 A;  4BN2 A;  4PFP A;  3KEN A;  2O0A A;  1YRS A;  4FRZ A;  3ZCW A;  3ZFD A;  4E7S A;  2XAE A;  2VAS A;  2ZFL A;  1D0X A;  4A5Y A;  5LT4 A;  5LT3 A;  1MMD A;  4ZHI A;  2OWM A;  4E7Z A;  3K5E A;  5GSZ A;  1F9V A;  1VOM A;  1N6M A;  2UYM A;  3CNZ A;  3KIN A;  2MYS A;  4PJL A;  4UBF A;  3BFN A;  3ZFC A;  1V8K A;  3DC4 A;  1F9U A;  2ZFJ A;  1GOJ A;  4PFO A;  2V26 A;  2IEH A;  3B6U A;  4BBG A;  1VFZ A;  3CJO A;  3H4S A;  3NWN A;  1MKJ A;  4A50 A;  4GKP A;  1VFV A;  2WOG A;  4Y05 A;  3B6V A;  3X2T A;  4PJN A;  4A14 A;  2GM1 A;  1F9W A;  4ZCA A;  2Y65 A;  1T5C A;  1BR2 A;  3WRD A;  3U06 A;  1LVK A;  2KIN A;  2X7C A;  1VFW A;  4AP0 A;  4B7B A;  3L1C A;  1G8X A;  3L9H A;  4ETP B;  1VFX A;  4GKR A;  2HEH A;  3K3B A;  4AS7 A;  2X2R A;  3T0Q A;  2FME A;  1MMG A;  5LT1 A;  1D0Y A;  4BXN A;  1FMV A;  5LT2 A;  1LKX A;  1D1A A;  1MMA A;  2PG2 A;  1I5S A;  4A51 A;  3DCB A;  2NCD A;  1I6I A;  3COB A;  1SDM A;  1MNE A;  2XT3 A;  4PJJ A;  4DBR A;  4A1Z A;  2FL6 A;  2ZFK A;  5LT0 A;  4PJM A;  1D0Z A;  1RY6 A;  2VB6 A;  2X7E A;  3LRE A;  4GKQ A;  4ETP A;  2UYI A;  3PXN A;  1X88 A;  2X7D A;  1D1C A;  4H1G A;  2Q2Z A;  1F9T A;  5HLE A;  2FL2 A;  2Q2Y A;  1KK7 A;  1BG2 A;  2FKY A;  4A28 A;  1BR4 A;  1BR1 A;  1Q0B A;  1FMW A;  2Y5W A;  3KAR A; 
#chains in the Genus database with same CATH homology
 3GBJ A;  2VVG A;  1D1B A;  2G1Q A;  2GRY A;  4DBQ A;  1V8J A;  3HQD A;  2ZFM A;  3WPN A;  4LNU K;  4ANJ A;  4PK4 A;  2X51 A;  1II6 A;  1MMN A;  2ZFI A;  4HNA K;  1CZ7 A;  4BN2 A;  4PFP A;  3KEN A;  1YRS A;  4FRZ A;  3ZCW A;  3ZFD A;  4E7S A;  2XAE A;  2VAS A;  2ZFL A;  1D0X A;  4A5Y A;  5LT4 A;  5LT3 A;  1MMD A;  4ZHI A;  2OWM A;  4E7Z A;  3K5E A;  5GSZ A;  1F9V A;  1VOM A;  1N6M A;  2UYM A;  3CNZ A;  3KIN A;  2MYS A;  4PJL A;  4UBF A;  3BFN A;  3ZFC A;  1V8K A;  3DC4 A;  1F9U A;  2ZFJ A;  1GOJ A;  4PFO A;  2V26 A;  2IEH A;  3B6U A;  4BBG A;  1VFZ A;  3CJO A;  3H4S A;  3NWN A;  1MKJ A;  4A50 A;  1VFV A;  2WOG A;  4Y05 A;  3B6V A;  3X2T A;  4PJN A;  4A14 A;  2GM1 A;  1F9W A;  4ZCA A;  2Y65 A;  1T5C A;  1BR2 A;  3WRD A;  3U06 A;  1LVK A;  2KIN A;  2X7C A;  1VFW A;  4AP0 A;  4B7B A;  3L1C A;  1G8X A;  3L9H A;  1VFX A;  4GKR A;  2HEH A;  3K3B A;  4AS7 A;  2X2R A;  3T0Q A;  2FME A;  1MMG A;  5LT1 A;  1D0Y A;  4BXN A;  1FMV A;  5LT2 A;  1LKX A;  1D1A A;  1MMA A;  2PG2 A;  1I5S A;  4A51 A;  3DCB A;  2NCD A;  1I6I A;  3COB A;  1SDM A;  1MNE A;  2XT3 A;  4PJJ A;  4DBR A;  4A1Z A;  2FL6 A;  2ZFK A;  5LT0 A;  4PJM A;  1D0Z A;  1RY6 A;  2VB6 A;  2X7E A;  3LRE A;  4ETP A;  2UYI A;  3PXN A;  1X88 A;  2X7D A;  1D1C A;  4H1G A;  2Q2Z A;  1F9T A;  5HLE A;  2FL2 A;  2Q2Y A;  1KK7 A;  1BG2 A;  2FKY A;  4A28 A;  1BR4 A;  1BR1 A;  1Q0B A;  1FMW A;  2Y5W A;  3KAR A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

2HEHA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations