2HEHA

Crystal structure of the kif2c motor domain
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
359
structure length
324
Chain Sequence
NWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGKGIYAMASRDVFLLKNQPCYRKLGLEVYVTFFEIYNGKLFDLLNKKAKLRVLEDGKQQVQVVGLQEHLVNSADDVIKMIDMGSACRNSSRSHACFQIILRAKGRMHGKFSLVDLAGNEGAEINKSLLALKECIRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIATISPGISSCEYTLNTLRYADRVKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the kif2c motor domain
rcsb
molecule tags Structural genomics, structural protein
source organism Homo sapiens
molecule keywords KIF2C protein
total genus 107
structure length 324
sequence length 359
ec nomenclature
pdb deposition date 2006-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 2hehA00
1FMVA 1VFVA 2X7EA 1G8XA 2ZFIA 2MYSA 4HNAK 2ZFKA 3KINA 1F9UA 3ZCWA 5LT1A 2VVGA 2UYIA 3U06A 1MMGA 3HQDA 4LNUK 4AP0A 5LT0A 3CJOA 1MMDA 1D1BA 1VFXA 1N6MA 3DCBA 1D0ZA 2IEHA 2FMEA 1MMAA 4A50A 2V26A 1FMWA 3PXNA 2FKYA 1D1CA 1D0XA 3BFNA 4AS7A 2X7CA 3NWNA 4UBFA 3LREA 3WPNA 4PK4A 1BR4A 2X51A 3L1CA 2X2RA 1GOJA 1CZ7A 5GSZA 2OWMA 4H1GA 2FL2A 2Q2ZA 1F9VA 5LT2A 4PJMA 3K5EA 2Y65A 4BN2A 1X88A 4GKRA 1BG2A 1YRSA 4FRZA 4ANJA 2NCDA 1BR2A 1LVKA 1F9WA 3ZFCA 4PJNA 4A14A 1D1AA 1KK7A 1VOMA 1MNEA 3CNZA 5HLEA 4A1ZA 3ZFDA 2VASA 4ZHIA 4A28A 3T0QA 2ZFLA 3KENA 5LT4A 3GBJA 4PFPA 2Y5WA 4A51A 1I6IA 2VB6A 4ZCAA 2PG2A 2KINA 3COBA 1MKJA 2X7DA 4B7BA 4E7ZA 4PFOA 1II6A 3X2TA 1V8KA 3B6VA 4A5YA 2G1QA 2UYMA 4DBRA 2FL6A 2GRYA 1VFWA 1SDMA 2ZFMA 3WRDA 2XT3A 1RY6A 4PJLA 2Q2YA 1BR1A 2XAEA 2ZFJA 1F9TA 4PJJA 2GM1A 1LKXA 5LT3A 1Q0BA 4ETPA 1VFZA 3B6UA 2HEHA 2WOGA 3L9HA 4DBQA 1I5SA 4Y05A 1T5CA 3K3BA 4E7SA 3H4SA 3DC4A 4BBGA 1D0YA 4BXNA 1MMNA 3KARA 1V8JA
chains in the Genus database with same CATH superfamily
1FMVA 1VFVA 2X7EA 1G8XA 2ZFIA 2MYSA 4HNAK 2ZFKA 3KINA 1F9UA 3ZCWA 5LT1A 2VVGA 2UYIA 3U06A 1MMGA 3HQDA 4GKPA 4LNUK 4AP0A 5LT0A 3CJOA 1MMDA 1D1BA 1VFXA 1N6MA 3DCBA 1D0ZA 2IEHA 2FMEA 1MMAA 4A50A 2V26A 1FMWA 3PXNA 2FKYA 1D1CA 1D0XA 3BFNA 4AS7A 2X7CA 3NWNA 4UBFA 3LREA 3WPNA 4PK4A 1BR4A 2X51A 3L1CA 2X2RA 1GOJA 1CZ7A 5GSZA 2OWMA 4H1GA 2FL2A 2Q2ZA 1F9VA 5LT2A 4PJMA 3K5EA 2Y65A 4BN2A 1X88A 4GKRA 1BG2A 1YRSA 4FRZA 4ANJA 2NCDA 1BR2A 1LVKA 1F9WA 3ZFCA 4PJNA 4A14A 1D1AA 1KK7A 2O0AA 1VOMA 1MNEA 3CNZA 5HLEA 4A1ZA 3ZFDA 2VASA 4ZHIA 4A28A 3T0QA 2ZFLA 3KENA 5LT4A 3GBJA 4PFPA 2Y5WA 4A51A 1I6IA 2VB6A 4ZCAA 2PG2A 2KINA 3COBA 1MKJA 2X7DA 4ETPB 4B7BA 4E7ZA 4PFOA 1II6A 3X2TA 1V8KA 3B6VA 4A5YA 2G1QA 2UYMA 4DBRA 2FL6A 2GRYA 1VFWA 1SDMA 2ZFMA 3WRDA 2XT3A 1RY6A 4PJLA 2Q2YA 1BR1A 2XAEA 2ZFJA 1F9TA 4PJJA 2GM1A 1LKXA 5LT3A 1Q0BA 4ETPA 1VFZA 3B6UA 2HEHA 2WOGA 3L9HA 4DBQA 1I5SA 4Y05A 1T5CA 3K3BA 4GKQA 4E7SA 3H4SA 3DC4A 4BBGA 1D0YA 4BXNA 1MMNA 3KARA 1V8JA
chains in the Genus database with same CATH topology
1FMVA 1VFVA 2X7EA 1G8XA 2ZFIA 2MYSA 4HNAK 2ZFKA 3KINA 1F9UA 3ZCWA 5LT1A 2VVGA 2UYIA 3U06A 1MMGA 3HQDA 4LNUK 4AP0A 5LT0A 3CJOA 1MMDA 1D1BA 1VFXA 1N6MA 3DCBA 1D0ZA 2IEHA 2FMEA 1MMAA 4A50A 2V26A 1FMWA 3PXNA 2FKYA 1D1CA 1D0XA 3BFNA 4AS7A 2X7CA 3NWNA 4UBFA 3LREA 3WPNA 4PK4A 1BR4A 2X51A 3L1CA 2X2RA 1GOJA 1CZ7A 5GSZA 2OWMA 4H1GA 2FL2A 2Q2ZA 1F9VA 5LT2A 4PJMA 3K5EA 2Y65A 4BN2A 1X88A 4GKRA 1BG2A 1YRSA 4FRZA 4ANJA 2NCDA 1BR2A 1LVKA 1F9WA 3ZFCA 4PJNA 4A14A 1D1AA 1KK7A 1VOMA 1MNEA 3CNZA 5HLEA 4A1ZA 3ZFDA 2VASA 4ZHIA 4A28A 3T0QA 2ZFLA 3KENA 5LT4A 3GBJA 4PFPA 2Y5WA 4A51A 1I6IA 2VB6A 4ZCAA 2PG2A 2KINA 3COBA 1MKJA 2X7DA 4B7BA 4E7ZA 4PFOA 1II6A 3X2TA 1V8KA 3B6VA 4A5YA 2G1QA 2UYMA 4DBRA 2FL6A 2GRYA 1VFWA 1SDMA 2ZFMA 3WRDA 2XT3A 1RY6A 4PJLA 2Q2YA 1BR1A 2XAEA 2ZFJA 1F9TA 4PJJA 2GM1A 1LKXA 5LT3A 1Q0BA 4ETPA 1VFZA 3B6UA 2HEHA 2WOGA 3L9HA 4DBQA 1I5SA 4Y05A 1T5CA 3K3BA 4E7SA 3H4SA 3DC4A 4BBGA 1D0YA 4BXNA 1MMNA 3KARA 1V8JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FMV A;  1VFV A;  2X7E A;  1G8X A;  2ZFI A;  2MYS A;  4HNA K;  2ZFK A;  3KIN A;  1F9U A;  3ZCW A;  5LT1 A;  2VVG A;  2UYI A;  3U06 A;  1MMG A;  3HQD A;  4LNU K;  4AP0 A;  5LT0 A;  3CJO A;  1MMD A;  1D1B A;  1VFX A;  1N6M A;  3DCB A;  1D0Z A;  2IEH A;  2FME A;  1MMA A;  4A50 A;  2V26 A;  1FMW A;  3PXN A;  2FKY A;  1D1C A;  1D0X A;  3BFN A;  4AS7 A;  2X7C A;  3NWN A;  4UBF A;  3LRE A;  3WPN A;  4PK4 A;  1BR4 A;  2X51 A;  3L1C A;  2X2R A;  1GOJ A;  1CZ7 A;  5GSZ A;  2OWM A;  4H1G A;  2FL2 A;  2Q2Z A;  1F9V A;  5LT2 A;  4PJM A;  3K5E A;  2Y65 A;  4BN2 A;  1X88 A;  4GKR A;  1BG2 A;  1YRS A;  4FRZ A;  4ANJ A;  2NCD A;  1BR2 A;  1LVK A;  1F9W A;  3ZFC A;  4PJN A;  4A14 A;  1D1A A;  1KK7 A;  1VOM A;  1MNE A;  3CNZ A;  5HLE A;  4A1Z A;  3ZFD A;  2VAS A;  4ZHI A;  4A28 A;  3T0Q A;  2ZFL A;  3KEN A;  5LT4 A;  3GBJ A;  4PFP A;  2Y5W A;  4A51 A;  1I6I A;  2VB6 A;  4ZCA A;  2PG2 A;  2KIN A;  3COB A;  1MKJ A;  2X7D A;  4B7B A;  4E7Z A;  4PFO A;  1II6 A;  3X2T A;  1V8K A;  3B6V A;  4A5Y A;  2G1Q A;  2UYM A;  4DBR A;  2FL6 A;  2GRY A;  1VFW A;  1SDM A;  2ZFM A;  3WRD A;  2XT3 A;  1RY6 A;  4PJL A;  2Q2Y A;  1BR1 A;  2XAE A;  2ZFJ A;  1F9T A;  4PJJ A;  2GM1 A;  1LKX A;  5LT3 A;  1Q0B A;  4ETP A;  1VFZ A;  3B6U A;  2HEH A;  2WOG A;  3L9H A;  4DBQ A;  1I5S A;  4Y05 A;  1T5C A;  3K3B A;  4E7S A;  3H4S A;  3DC4 A;  4BBG A;  1D0Y A;  4BXN A;  1MMN A;  3KAR A;  1V8J A; 
#chains in the Genus database with same CATH topology
 1FMV A;  1VFV A;  2X7E A;  1G8X A;  2ZFI A;  2MYS A;  4HNA K;  2ZFK A;  3KIN A;  1F9U A;  3ZCW A;  5LT1 A;  2VVG A;  2UYI A;  3U06 A;  1MMG A;  3HQD A;  4GKP A;  4LNU K;  4AP0 A;  5LT0 A;  3CJO A;  1MMD A;  1D1B A;  1VFX A;  1N6M A;  3DCB A;  1D0Z A;  2IEH A;  2FME A;  1MMA A;  4A50 A;  2V26 A;  1FMW A;  3PXN A;  2FKY A;  1D1C A;  1D0X A;  3BFN A;  4AS7 A;  2X7C A;  3NWN A;  4UBF A;  3LRE A;  3WPN A;  4PK4 A;  1BR4 A;  2X51 A;  3L1C A;  2X2R A;  1GOJ A;  1CZ7 A;  5GSZ A;  2OWM A;  4H1G A;  2FL2 A;  2Q2Z A;  1F9V A;  5LT2 A;  4PJM A;  3K5E A;  2Y65 A;  4BN2 A;  1X88 A;  4GKR A;  1BG2 A;  1YRS A;  4FRZ A;  4ANJ A;  2NCD A;  1BR2 A;  1LVK A;  1F9W A;  3ZFC A;  4PJN A;  4A14 A;  1D1A A;  1KK7 A;  2O0A A;  1VOM A;  1MNE A;  3CNZ A;  5HLE A;  4A1Z A;  3ZFD A;  2VAS A;  4ZHI A;  4A28 A;  3T0Q A;  2ZFL A;  3KEN A;  5LT4 A;  3GBJ A;  4PFP A;  2Y5W A;  4A51 A;  1I6I A;  2VB6 A;  4ZCA A;  2PG2 A;  2KIN A;  3COB A;  1MKJ A;  2X7D A;  4ETP B;  4B7B A;  4E7Z A;  4PFO A;  1II6 A;  3X2T A;  1V8K A;  3B6V A;  4A5Y A;  2G1Q A;  2UYM A;  4DBR A;  2FL6 A;  2GRY A;  1VFW A;  1SDM A;  2ZFM A;  3WRD A;  2XT3 A;  1RY6 A;  4PJL A;  2Q2Y A;  1BR1 A;  2XAE A;  2ZFJ A;  1F9T A;  4PJJ A;  2GM1 A;  1LKX A;  5LT3 A;  1Q0B A;  4ETP A;  1VFZ A;  3B6U A;  2HEH A;  2WOG A;  3L9H A;  4DBQ A;  1I5S A;  4Y05 A;  1T5C A;  3K3B A;  4GKQ A;  4E7S A;  3H4S A;  3DC4 A;  4BBG A;  1D0Y A;  4BXN A;  1MMN A;  3KAR A;  1V8J A; 
#chains in the Genus database with same CATH homology
 1FMV A;  1VFV A;  2X7E A;  1G8X A;  2ZFI A;  2MYS A;  4HNA K;  2ZFK A;  3KIN A;  1F9U A;  3ZCW A;  5LT1 A;  2VVG A;  2UYI A;  3U06 A;  1MMG A;  3HQD A;  4LNU K;  4AP0 A;  5LT0 A;  3CJO A;  1MMD A;  1D1B A;  1VFX A;  1N6M A;  3DCB A;  1D0Z A;  2IEH A;  2FME A;  1MMA A;  4A50 A;  2V26 A;  1FMW A;  3PXN A;  2FKY A;  1D1C A;  1D0X A;  3BFN A;  4AS7 A;  2X7C A;  3NWN A;  4UBF A;  3LRE A;  3WPN A;  4PK4 A;  1BR4 A;  2X51 A;  3L1C A;  2X2R A;  1GOJ A;  1CZ7 A;  5GSZ A;  2OWM A;  4H1G A;  2FL2 A;  2Q2Z A;  1F9V A;  5LT2 A;  4PJM A;  3K5E A;  2Y65 A;  4BN2 A;  1X88 A;  4GKR A;  1BG2 A;  1YRS A;  4FRZ A;  4ANJ A;  2NCD A;  1BR2 A;  1LVK A;  1F9W A;  3ZFC A;  4PJN A;  4A14 A;  1D1A A;  1KK7 A;  1VOM A;  1MNE A;  3CNZ A;  5HLE A;  4A1Z A;  3ZFD A;  2VAS A;  4ZHI A;  4A28 A;  3T0Q A;  2ZFL A;  3KEN A;  5LT4 A;  3GBJ A;  4PFP A;  2Y5W A;  4A51 A;  1I6I A;  2VB6 A;  4ZCA A;  2PG2 A;  2KIN A;  3COB A;  1MKJ A;  2X7D A;  4B7B A;  4E7Z A;  4PFO A;  1II6 A;  3X2T A;  1V8K A;  3B6V A;  4A5Y A;  2G1Q A;  2UYM A;  4DBR A;  2FL6 A;  2GRY A;  1VFW A;  1SDM A;  2ZFM A;  3WRD A;  2XT3 A;  1RY6 A;  4PJL A;  2Q2Y A;  1BR1 A;  2XAE A;  2ZFJ A;  1F9T A;  4PJJ A;  2GM1 A;  1LKX A;  5LT3 A;  1Q0B A;  4ETP A;  1VFZ A;  3B6U A;  2HEH A;  2WOG A;  3L9H A;  4DBQ A;  1I5S A;  4Y05 A;  1T5C A;  3K3B A;  4E7S A;  3H4S A;  3DC4 A;  4BBG A;  1D0Y A;  4BXN A;  1MMN A;  3KAR A;  1V8J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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