2WOG | Genus

Total Genus 111

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	111
sequence length	348
structure length	333
Chain Sequence	KNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Cell cycle
source organism	Homo sapiens
publication title	An Allosteric Transition Trapped in an Intermediate State of a New Kinesin-Inhibitor Complex. pubmed doi rcsb
molecule keywords	KINESIN-LIKE PROTEIN KIF11
total genus	111
structure length	333
sequence length	348
chains with identical sequence	B, C
ec nomenclature
pdb deposition date	2009-07-23

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00225	Kinesin	Kinesin motor domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.850.10	Alpha Beta	3-Layer(aba) Sandwich	Kinesin	Kinesin motor domain	2wogA00

1T5CA 1BR1A 1F9TA 3CJOA 3H4SA 2XAEA 4A51A 1CZ7A 5LT4A 3NWNA 4DBRA 2FKYA 4A14A 3HQDA 3COBA 4PJJA 3K5EA 3KARA 4DBQA 1VFWA 4ZHIA 3BFNA 2X51A 4A50A 3L1CA 1LKXA 2X2RA 3PXNA 4AS7A 1BG2A 2XT3A 2GM1A 2VASA 5LT2A 3WRDA 1D0XA 1D1BA 2V26A 4H1GA 1FMVA 2VVGA 1N6MA 4ANJA 1MKJA 3WPNA 2WOGA 1D0ZA 1MMDA 3U06A 1II6A 4A28A 2PG2A 4PK4A 4AP0A 3K3BA 1GOJA 3DC4A 1MMAA 2ZFLA 1VFZA 3T0QA 2X7DA 1F9VA 2ZFMA 2IEHA 2FL6A 1RY6A 1VOMA 4ZCAA 2GRYA 2UYMA 4PJNA 1MNEA 4ETPA 1Q0BA 1D1AA 3L9HA 1V8JA 4PJLA 4A1ZA 2FMEA 3GBJA 4FRZA 2ZFKA 2OWMA 4LNUK 1MMNA 1SDMA 3KENA 1LVKA 2UYIA 4UBFA 1BR4A 4PJMA 1V8KA 2ZFJA 2NCDA 4E7ZA 4E7SA 4BBGA 1D0YA 1KK7A 1I6IA 1X88A 2ZFIA 3KINA 2Y65A 2X7CA 1G8XA 3B6UA 2KINA 1F9UA 4BXNA 3ZFCA 4BN2A 2X7EA 2Q2YA 1YRSA 5LT1A 2Y5WA 3CNZA 4Y05A 4A5YA 3B6VA 4B7BA 1VFVA 5LT3A 1F9WA 1I5SA 3ZFDA 3X2TA 1MMGA 2Q2ZA 2FL2A 2G1QA 1D1CA 4PFOA 1FMWA 2VB6A 5LT0A 5HLEA 1VFXA 3LREA 3ZCWA 2MYSA 1BR2A 4HNAK 5GSZA 3DCBA 4GKRA 4PFPA 2HEHA
chains in the Genus database with same CATH superfamily

1T5CA 1BR1A 1F9TA 3CJOA 3H4SA 4GKPA 2XAEA 4A51A 1CZ7A 5LT4A 3NWNA 4DBRA 2FKYA 4A14A 3HQDA 3COBA 4PJJA 3K5EA 3KARA 4DBQA 1VFWA 4ZHIA 3BFNA 2X51A 4A50A 3L1CA 1LKXA 2X2RA 3PXNA 4AS7A 1BG2A 2XT3A 2GM1A 2VASA 5LT2A 3WRDA 1D0XA 1D1BA 2V26A 4H1GA 1FMVA 2VVGA 1N6MA 4ANJA 1MKJA 3WPNA 2WOGA 1D0ZA 1MMDA 3U06A 1II6A 4ETPB 4A28A 2PG2A 4PK4A 4AP0A 3K3BA 1GOJA 3DC4A 1MMAA 2ZFLA 1VFZA 3T0QA 2X7DA 1F9VA 2ZFMA 2IEHA 2FL6A 1RY6A 1VOMA 4ZCAA 2GRYA 2UYMA 4PJNA 1MNEA 4ETPA 1Q0BA 1D1AA 3L9HA 1V8JA 4PJLA 4A1ZA 2FMEA 3GBJA 4FRZA 2ZFKA 2OWMA 4LNUK 1MMNA 1SDMA 3KENA 1LVKA 2UYIA 4UBFA 1BR4A 4PJMA 1V8KA 2ZFJA 2NCDA 4E7ZA 4E7SA 4BBGA 1D0YA 1KK7A 1I6IA 1X88A 2ZFIA 3KINA 2Y65A 2O0AA 2X7CA 1G8XA 3B6UA 2KINA 1F9UA 4BXNA 3ZFCA 4BN2A 2X7EA 2Q2YA 1YRSA 5LT1A 2Y5WA 3CNZA 4Y05A 4A5YA 3B6VA 4B7BA 1VFVA 5LT3A 1F9WA 1I5SA 3ZFDA 3X2TA 1MMGA 2Q2ZA 2FL2A 2G1QA 1D1CA 4GKQA 4PFOA 1FMWA 2VB6A 5LT0A 5HLEA 1VFXA 3LREA 3ZCWA 2MYSA 1BR2A 4HNAK 5GSZA 3DCBA 4GKRA 4PFPA 2HEHA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1T5C A;  1BR1 A;  1F9T A;  3CJO A;  3H4S A;  2XAE A;  4A51 A;  1CZ7 A;  5LT4 A;  3NWN A;  4DBR A;  2FKY A;  4A14 A;  3HQD A;  3COB A;  4PJJ A;  3K5E A;  3KAR A;  4DBQ A;  1VFW A;  4ZHI A;  3BFN A;  2X51 A;  4A50 A;  3L1C A;  1LKX A;  2X2R A;  3PXN A;  4AS7 A;  1BG2 A;  2XT3 A;  2GM1 A;  2VAS A;  5LT2 A;  3WRD A;  1D0X A;  1D1B A;  2V26 A;  4H1G A;  1FMV A;  2VVG A;  1N6M A;  4ANJ A;  1MKJ A;  3WPN A;  2WOG A;  1D0Z A;  1MMD A;  3U06 A;  1II6 A;  4A28 A;  2PG2 A;  4PK4 A;  4AP0 A;  3K3B A;  1GOJ A;  3DC4 A;  1MMA A;  2ZFL A;  1VFZ A;  3T0Q A;  2X7D A;  1F9V A;  2ZFM A;  2IEH A;  2FL6 A;  1RY6 A;  1VOM A;  4ZCA A;  2GRY A;  2UYM A;  4PJN A;  1MNE A;  4ETP A;  1Q0B A;  1D1A A;  3L9H A;  1V8J A;  4PJL A;  4A1Z A;  2FME A;  3GBJ A;  4FRZ A;  2ZFK A;  2OWM A;  4LNU K;  1MMN A;  1SDM A;  3KEN A;  1LVK A;  2UYI A;  4UBF A;  1BR4 A;  4PJM A;  1V8K A;  2ZFJ A;  2NCD A;  4E7Z A;  4E7S A;  4BBG A;  1D0Y A;  1KK7 A;  1I6I A;  1X88 A;  2ZFI A;  3KIN A;  2Y65 A;  2X7C A;  1G8X A;  3B6U A;  2KIN A;  1F9U A;  4BXN A;  3ZFC A;  4BN2 A;  2X7E A;  2Q2Y A;  1YRS A;  5LT1 A;  2Y5W A;  3CNZ A;  4Y05 A;  4A5Y A;  3B6V A;  4B7B A;  1VFV A;  5LT3 A;  1F9W A;  1I5S A;  3ZFD A;  3X2T A;  1MMG A;  2Q2Z A;  2FL2 A;  2G1Q A;  1D1C A;  4PFO A;  1FMW A;  2VB6 A;  5LT0 A;  5HLE A;  1VFX A;  3LRE A;  3ZCW A;  2MYS A;  1BR2 A;  4HNA K;  5GSZ A;  3DCB A;  4GKR A;  4PFP A;  2HEH A; 
#chains in the Genus database with same CATH topology
 1T5C A;  1BR1 A;  1F9T A;  3CJO A;  3H4S A;  4GKP A;  2XAE A;  4A51 A;  1CZ7 A;  5LT4 A;  3NWN A;  4DBR A;  2FKY A;  4A14 A;  3HQD A;  3COB A;  4PJJ A;  3K5E A;  3KAR A;  4DBQ A;  1VFW A;  4ZHI A;  3BFN A;  2X51 A;  4A50 A;  3L1C A;  1LKX A;  2X2R A;  3PXN A;  4AS7 A;  1BG2 A;  2XT3 A;  2GM1 A;  2VAS A;  5LT2 A;  3WRD A;  1D0X A;  1D1B A;  2V26 A;  4H1G A;  1FMV A;  2VVG A;  1N6M A;  4ANJ A;  1MKJ A;  3WPN A;  2WOG A;  1D0Z A;  1MMD A;  3U06 A;  1II6 A;  4ETP B;  4A28 A;  2PG2 A;  4PK4 A;  4AP0 A;  3K3B A;  1GOJ A;  3DC4 A;  1MMA A;  2ZFL A;  1VFZ A;  3T0Q A;  2X7D A;  1F9V A;  2ZFM A;  2IEH A;  2FL6 A;  1RY6 A;  1VOM A;  4ZCA A;  2GRY A;  2UYM A;  4PJN A;  1MNE A;  4ETP A;  1Q0B A;  1D1A A;  3L9H A;  1V8J A;  4PJL A;  4A1Z A;  2FME A;  3GBJ A;  4FRZ A;  2ZFK A;  2OWM A;  4LNU K;  1MMN A;  1SDM A;  3KEN A;  1LVK A;  2UYI A;  4UBF A;  1BR4 A;  4PJM A;  1V8K A;  2ZFJ A;  2NCD A;  4E7Z A;  4E7S A;  4BBG A;  1D0Y A;  1KK7 A;  1I6I A;  1X88 A;  2ZFI A;  3KIN A;  2Y65 A;  2O0A A;  2X7C A;  1G8X A;  3B6U A;  2KIN A;  1F9U A;  4BXN A;  3ZFC A;  4BN2 A;  2X7E A;  2Q2Y A;  1YRS A;  5LT1 A;  2Y5W A;  3CNZ A;  4Y05 A;  4A5Y A;  3B6V A;  4B7B A;  1VFV A;  5LT3 A;  1F9W A;  1I5S A;  3ZFD A;  3X2T A;  1MMG A;  2Q2Z A;  2FL2 A;  2G1Q A;  1D1C A;  4GKQ A;  4PFO A;  1FMW A;  2VB6 A;  5LT0 A;  5HLE A;  1VFX A;  3LRE A;  3ZCW A;  2MYS A;  1BR2 A;  4HNA K;  5GSZ A;  3DCB A;  4GKR A;  4PFP A;  2HEH A; 
#chains in the Genus database with same CATH homology
 1T5C A;  1BR1 A;  1F9T A;  3CJO A;  3H4S A;  2XAE A;  4A51 A;  1CZ7 A;  5LT4 A;  3NWN A;  4DBR A;  2FKY A;  4A14 A;  3HQD A;  3COB A;  4PJJ A;  3K5E A;  3KAR A;  4DBQ A;  1VFW A;  4ZHI A;  3BFN A;  2X51 A;  4A50 A;  3L1C A;  1LKX A;  2X2R A;  3PXN A;  4AS7 A;  1BG2 A;  2XT3 A;  2GM1 A;  2VAS A;  5LT2 A;  3WRD A;  1D0X A;  1D1B A;  2V26 A;  4H1G A;  1FMV A;  2VVG A;  1N6M A;  4ANJ A;  1MKJ A;  3WPN A;  2WOG A;  1D0Z A;  1MMD A;  3U06 A;  1II6 A;  4A28 A;  2PG2 A;  4PK4 A;  4AP0 A;  3K3B A;  1GOJ A;  3DC4 A;  1MMA A;  2ZFL A;  1VFZ A;  3T0Q A;  2X7D A;  1F9V A;  2ZFM A;  2IEH A;  2FL6 A;  1RY6 A;  1VOM A;  4ZCA A;  2GRY A;  2UYM A;  4PJN A;  1MNE A;  4ETP A;  1Q0B A;  1D1A A;  3L9H A;  1V8J A;  4PJL A;  4A1Z A;  2FME A;  3GBJ A;  4FRZ A;  2ZFK A;  2OWM A;  4LNU K;  1MMN A;  1SDM A;  3KEN A;  1LVK A;  2UYI A;  4UBF A;  1BR4 A;  4PJM A;  1V8K A;  2ZFJ A;  2NCD A;  4E7Z A;  4E7S A;  4BBG A;  1D0Y A;  1KK7 A;  1I6I A;  1X88 A;  2ZFI A;  3KIN A;  2Y65 A;  2X7C A;  1G8X A;  3B6U A;  2KIN A;  1F9U A;  4BXN A;  3ZFC A;  4BN2 A;  2X7E A;  2Q2Y A;  1YRS A;  5LT1 A;  2Y5W A;  3CNZ A;  4Y05 A;  4A5Y A;  3B6V A;  4B7B A;  1VFV A;  5LT3 A;  1F9W A;  1I5S A;  3ZFD A;  3X2T A;  1MMG A;  2Q2Z A;  2FL2 A;  2G1Q A;  1D1C A;  4PFO A;  1FMW A;  2VB6 A;  5LT0 A;  5HLE A;  1VFX A;  3LRE A;  3ZCW A;  2MYS A;  1BR2 A;  4HNA K;  5GSZ A;  3DCB A;  4GKR A;  4PFP A;  2HEH A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2WOGA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations