2Y5WA

Crystal structure of drosophila melanogaster kinesin-1 motor domain dimer
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
347
structure length
334
Chain Sequence
EDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIAGKVYLFDKVFKPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDIFNHIYAMEVNLEFHIKVSYYEIYMDKIRDLLDVSKVNLSVHEDKNRVPYVKGATERFVSSPEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLINVKQENLENQKKLSGKLYLVDLAGSEKVKNINKSLSALGNVISALADGNKTHIPYRDSKLTRILQESLGGNARTTIVICCSPASFNESETKSTLDFGRRAKTVKNVVCVNEELTAEEWKRRYEKEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the Kinesin-1 Motor-Tail Complex Reveals the Mechanism of Autoinhibition.
pubmed doi rcsb
molecule tags Motor protein
source organism Drosophila melanogaster
molecule keywords KINESIN HEAVY CHAIN
total genus 105
structure length 334
sequence length 347
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-01-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 2y5wA00
2G1QA 2Q2YA 3KINA 1F9UA 1SDMA 2XT3A 3COBA 1VOMA 4LNUK 2X51A 4ZCAA 3L1CA 4B7BA 2HEHA 4UBFA 1MKJA 4A50A 3WPNA 4ETPA 3T0QA 4ANJA 1Q0BA 5LT1A 1F9WA 1MMAA 3B6UA 3CJOA 2VB6A 1D0ZA 4PJLA 3GBJA 1N6MA 3NWNA 4A28A 2ZFIA 2ZFKA 2FL6A 3KENA 1MMNA 2ZFJA 2V26A 3LREA 3WRDA 3X2TA 3K5EA 1LVKA 1FMVA 1VFXA 2FKYA 1MMDA 2Q2ZA 5GSZA 3K3BA 2KINA 4PJNA 4GKRA 4HNAK 3DCBA 4A14A 1BG2A 1D1AA 2MYSA 3ZFDA 3PXNA 4BN2A 1CZ7A 4H1GA 5LT3A 1RY6A 1I5SA 1MMGA 1I6IA 1V8JA 4A5YA 2GM1A 3ZFCA 1D1CA 5LT0A 1YRSA 5LT4A 3KARA 2VVGA 4FRZA 3CNZA 2ZFLA 4BBGA 1II6A 1X88A 4PK4A 1VFVA 2WOGA 2XAEA 4AS7A 1VFZA 4PJJA 3L9HA 4DBQA 2UYIA 2Y5WA 2X7EA 1VFWA 3BFNA 3B6VA 4A1ZA 4DBRA 4PFOA 1LKXA 2Y65A 1G8XA 1T5CA 3DC4A 2OWMA 4AP0A 3H4SA 4PJMA 2IEHA 4A51A 4E7ZA 1FMWA 2FL2A 4BXNA 5LT2A 4Y05A 1D1BA 4ZHIA 4PFPA 1V8KA 2PG2A 2ZFMA 1F9VA 3ZCWA 1GOJA 4E7SA 2X2RA 1BR4A 1BR1A 3U06A 1F9TA 1D0XA 3HQDA 2FMEA 1KK7A 1MNEA 2X7DA 2X7CA 1BR2A 1D0YA 2UYMA 2NCDA 2VASA 5HLEA 2GRYA
chains in the Genus database with same CATH superfamily
2G1QA 2Q2YA 3KINA 1F9UA 1SDMA 2XT3A 3COBA 1VOMA 4LNUK 2X51A 4ZCAA 3L1CA 4B7BA 2HEHA 4UBFA 1MKJA 4A50A 3WPNA 4ETPA 3T0QA 4ANJA 1Q0BA 5LT1A 1F9WA 1MMAA 3B6UA 3CJOA 2VB6A 1D0ZA 4PJLA 3GBJA 1N6MA 3NWNA 4A28A 2ZFIA 2ZFKA 2FL6A 3KENA 1MMNA 2ZFJA 2V26A 3LREA 3WRDA 3X2TA 3K5EA 1LVKA 1FMVA 1VFXA 2FKYA 1MMDA 2Q2ZA 5GSZA 3K3BA 2KINA 4PJNA 4GKRA 4ETPB 4HNAK 3DCBA 4A14A 1BG2A 1D1AA 2MYSA 3ZFDA 3PXNA 4BN2A 1CZ7A 4H1GA 5LT3A 1RY6A 1I5SA 1MMGA 1I6IA 1V8JA 4A5YA 2GM1A 3ZFCA 1D1CA 5LT0A 1YRSA 5LT4A 3KARA 2VVGA 4FRZA 3CNZA 2ZFLA 4BBGA 1II6A 1X88A 4PK4A 1VFVA 2WOGA 2XAEA 4AS7A 1VFZA 4PJJA 3L9HA 4DBQA 2UYIA 2Y5WA 2X7EA 1VFWA 3BFNA 3B6VA 4A1ZA 4DBRA 4PFOA 1LKXA 2Y65A 1G8XA 1T5CA 3DC4A 2OWMA 4GKPA 4AP0A 3H4SA 4PJMA 2IEHA 4A51A 4E7ZA 1FMWA 2FL2A 4BXNA 5LT2A 4Y05A 1D1BA 2O0AA 4ZHIA 4PFPA 1V8KA 2PG2A 2ZFMA 1F9VA 3ZCWA 1GOJA 4E7SA 2X2RA 1BR4A 1BR1A 3U06A 1F9TA 1D0XA 3HQDA 2FMEA 1KK7A 1MNEA 2X7DA 2X7CA 1BR2A 4GKQA 1D0YA 2UYMA 2NCDA 2VASA 5HLEA 2GRYA
chains in the Genus database with same CATH topology
2G1QA 2Q2YA 3KINA 1F9UA 1SDMA 2XT3A 3COBA 1VOMA 4LNUK 2X51A 4ZCAA 3L1CA 4B7BA 2HEHA 4UBFA 1MKJA 4A50A 3WPNA 4ETPA 3T0QA 4ANJA 1Q0BA 5LT1A 1F9WA 1MMAA 3B6UA 3CJOA 2VB6A 1D0ZA 4PJLA 3GBJA 1N6MA 3NWNA 4A28A 2ZFIA 2ZFKA 2FL6A 3KENA 1MMNA 2ZFJA 2V26A 3LREA 3WRDA 3X2TA 3K5EA 1LVKA 1FMVA 1VFXA 2FKYA 1MMDA 2Q2ZA 5GSZA 3K3BA 2KINA 4PJNA 4GKRA 4HNAK 3DCBA 4A14A 1BG2A 1D1AA 2MYSA 3ZFDA 3PXNA 4BN2A 1CZ7A 4H1GA 5LT3A 1RY6A 1I5SA 1MMGA 1I6IA 1V8JA 4A5YA 2GM1A 3ZFCA 1D1CA 5LT0A 1YRSA 5LT4A 3KARA 2VVGA 4FRZA 3CNZA 2ZFLA 4BBGA 1II6A 1X88A 4PK4A 1VFVA 2WOGA 2XAEA 4AS7A 1VFZA 4PJJA 3L9HA 4DBQA 2UYIA 2Y5WA 2X7EA 1VFWA 3BFNA 3B6VA 4A1ZA 4DBRA 4PFOA 1LKXA 2Y65A 1G8XA 1T5CA 3DC4A 2OWMA 4AP0A 3H4SA 4PJMA 2IEHA 4A51A 4E7ZA 1FMWA 2FL2A 4BXNA 5LT2A 4Y05A 1D1BA 4ZHIA 4PFPA 1V8KA 2PG2A 2ZFMA 1F9VA 3ZCWA 1GOJA 4E7SA 2X2RA 1BR4A 1BR1A 3U06A 1F9TA 1D0XA 3HQDA 2FMEA 1KK7A 1MNEA 2X7DA 2X7CA 1BR2A 1D0YA 2UYMA 2NCDA 2VASA 5HLEA 2GRYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2G1Q A;  2Q2Y A;  3KIN A;  1F9U A;  1SDM A;  2XT3 A;  3COB A;  1VOM A;  4LNU K;  2X51 A;  4ZCA A;  3L1C A;  4B7B A;  2HEH A;  4UBF A;  1MKJ A;  4A50 A;  3WPN A;  4ETP A;  3T0Q A;  4ANJ A;  1Q0B A;  5LT1 A;  1F9W A;  1MMA A;  3B6U A;  3CJO A;  2VB6 A;  1D0Z A;  4PJL A;  3GBJ A;  1N6M A;  3NWN A;  4A28 A;  2ZFI A;  2ZFK A;  2FL6 A;  3KEN A;  1MMN A;  2ZFJ A;  2V26 A;  3LRE A;  3WRD A;  3X2T A;  3K5E A;  1LVK A;  1FMV A;  1VFX A;  2FKY A;  1MMD A;  2Q2Z A;  5GSZ A;  3K3B A;  2KIN A;  4PJN A;  4GKR A;  4HNA K;  3DCB A;  4A14 A;  1BG2 A;  1D1A A;  2MYS A;  3ZFD A;  3PXN A;  4BN2 A;  1CZ7 A;  4H1G A;  5LT3 A;  1RY6 A;  1I5S A;  1MMG A;  1I6I A;  1V8J A;  4A5Y A;  2GM1 A;  3ZFC A;  1D1C A;  5LT0 A;  1YRS A;  5LT4 A;  3KAR A;  2VVG A;  4FRZ A;  3CNZ A;  2ZFL A;  4BBG A;  1II6 A;  1X88 A;  4PK4 A;  1VFV A;  2WOG A;  2XAE A;  4AS7 A;  1VFZ A;  4PJJ A;  3L9H A;  4DBQ A;  2UYI A;  2Y5W A;  2X7E A;  1VFW A;  3BFN A;  3B6V A;  4A1Z A;  4DBR A;  4PFO A;  1LKX A;  2Y65 A;  1G8X A;  1T5C A;  3DC4 A;  2OWM A;  4AP0 A;  3H4S A;  4PJM A;  2IEH A;  4A51 A;  4E7Z A;  1FMW A;  2FL2 A;  4BXN A;  5LT2 A;  4Y05 A;  1D1B A;  4ZHI A;  4PFP A;  1V8K A;  2PG2 A;  2ZFM A;  1F9V A;  3ZCW A;  1GOJ A;  4E7S A;  2X2R A;  1BR4 A;  1BR1 A;  3U06 A;  1F9T A;  1D0X A;  3HQD A;  2FME A;  1KK7 A;  1MNE A;  2X7D A;  2X7C A;  1BR2 A;  1D0Y A;  2UYM A;  2NCD A;  2VAS A;  5HLE A;  2GRY A; 
#chains in the Genus database with same CATH topology
 2G1Q A;  2Q2Y A;  3KIN A;  1F9U A;  1SDM A;  2XT3 A;  3COB A;  1VOM A;  4LNU K;  2X51 A;  4ZCA A;  3L1C A;  4B7B A;  2HEH A;  4UBF A;  1MKJ A;  4A50 A;  3WPN A;  4ETP A;  3T0Q A;  4ANJ A;  1Q0B A;  5LT1 A;  1F9W A;  1MMA A;  3B6U A;  3CJO A;  2VB6 A;  1D0Z A;  4PJL A;  3GBJ A;  1N6M A;  3NWN A;  4A28 A;  2ZFI A;  2ZFK A;  2FL6 A;  3KEN A;  1MMN A;  2ZFJ A;  2V26 A;  3LRE A;  3WRD A;  3X2T A;  3K5E A;  1LVK A;  1FMV A;  1VFX A;  2FKY A;  1MMD A;  2Q2Z A;  5GSZ A;  3K3B A;  2KIN A;  4PJN A;  4GKR A;  4ETP B;  4HNA K;  3DCB A;  4A14 A;  1BG2 A;  1D1A A;  2MYS A;  3ZFD A;  3PXN A;  4BN2 A;  1CZ7 A;  4H1G A;  5LT3 A;  1RY6 A;  1I5S A;  1MMG A;  1I6I A;  1V8J A;  4A5Y A;  2GM1 A;  3ZFC A;  1D1C A;  5LT0 A;  1YRS A;  5LT4 A;  3KAR A;  2VVG A;  4FRZ A;  3CNZ A;  2ZFL A;  4BBG A;  1II6 A;  1X88 A;  4PK4 A;  1VFV A;  2WOG A;  2XAE A;  4AS7 A;  1VFZ A;  4PJJ A;  3L9H A;  4DBQ A;  2UYI A;  2Y5W A;  2X7E A;  1VFW A;  3BFN A;  3B6V A;  4A1Z A;  4DBR A;  4PFO A;  1LKX A;  2Y65 A;  1G8X A;  1T5C A;  3DC4 A;  2OWM A;  4GKP A;  4AP0 A;  3H4S A;  4PJM A;  2IEH A;  4A51 A;  4E7Z A;  1FMW A;  2FL2 A;  4BXN A;  5LT2 A;  4Y05 A;  1D1B A;  2O0A A;  4ZHI A;  4PFP A;  1V8K A;  2PG2 A;  2ZFM A;  1F9V A;  3ZCW A;  1GOJ A;  4E7S A;  2X2R A;  1BR4 A;  1BR1 A;  3U06 A;  1F9T A;  1D0X A;  3HQD A;  2FME A;  1KK7 A;  1MNE A;  2X7D A;  2X7C A;  1BR2 A;  4GKQ A;  1D0Y A;  2UYM A;  2NCD A;  2VAS A;  5HLE A;  2GRY A; 
#chains in the Genus database with same CATH homology
 2G1Q A;  2Q2Y A;  3KIN A;  1F9U A;  1SDM A;  2XT3 A;  3COB A;  1VOM A;  4LNU K;  2X51 A;  4ZCA A;  3L1C A;  4B7B A;  2HEH A;  4UBF A;  1MKJ A;  4A50 A;  3WPN A;  4ETP A;  3T0Q A;  4ANJ A;  1Q0B A;  5LT1 A;  1F9W A;  1MMA A;  3B6U A;  3CJO A;  2VB6 A;  1D0Z A;  4PJL A;  3GBJ A;  1N6M A;  3NWN A;  4A28 A;  2ZFI A;  2ZFK A;  2FL6 A;  3KEN A;  1MMN A;  2ZFJ A;  2V26 A;  3LRE A;  3WRD A;  3X2T A;  3K5E A;  1LVK A;  1FMV A;  1VFX A;  2FKY A;  1MMD A;  2Q2Z A;  5GSZ A;  3K3B A;  2KIN A;  4PJN A;  4GKR A;  4HNA K;  3DCB A;  4A14 A;  1BG2 A;  1D1A A;  2MYS A;  3ZFD A;  3PXN A;  4BN2 A;  1CZ7 A;  4H1G A;  5LT3 A;  1RY6 A;  1I5S A;  1MMG A;  1I6I A;  1V8J A;  4A5Y A;  2GM1 A;  3ZFC A;  1D1C A;  5LT0 A;  1YRS A;  5LT4 A;  3KAR A;  2VVG A;  4FRZ A;  3CNZ A;  2ZFL A;  4BBG A;  1II6 A;  1X88 A;  4PK4 A;  1VFV A;  2WOG A;  2XAE A;  4AS7 A;  1VFZ A;  4PJJ A;  3L9H A;  4DBQ A;  2UYI A;  2Y5W A;  2X7E A;  1VFW A;  3BFN A;  3B6V A;  4A1Z A;  4DBR A;  4PFO A;  1LKX A;  2Y65 A;  1G8X A;  1T5C A;  3DC4 A;  2OWM A;  4AP0 A;  3H4S A;  4PJM A;  2IEH A;  4A51 A;  4E7Z A;  1FMW A;  2FL2 A;  4BXN A;  5LT2 A;  4Y05 A;  1D1B A;  4ZHI A;  4PFP A;  1V8K A;  2PG2 A;  2ZFM A;  1F9V A;  3ZCW A;  1GOJ A;  4E7S A;  2X2R A;  1BR4 A;  1BR1 A;  3U06 A;  1F9T A;  1D0X A;  3HQD A;  2FME A;  1KK7 A;  1MNE A;  2X7D A;  2X7C A;  1BR2 A;  1D0Y A;  2UYM A;  2NCD A;  2VAS A;  5HLE A;  2GRY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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