3K5EA

The structure of human kinesin-like motor protein kif11/ksp/eg5 in complex with adp and enastrol.
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
346
structure length
329
Chain Sequence
NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGDKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of human kinesin-like motor protein Kif11/KSP/Eg5 in complex with ADP and enastrol.
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Kinesin-like protein KIF11
total genus 101
structure length 329
sequence length 346
chains with identical sequence B
ec nomenclature ec 3.6.4.4: Transferred entry: 5.6.1.3.
pdb deposition date 2009-10-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 3k5eA00
2XT3A 1D0XA 3KARA 1YRSA 1VOMA 2FKYA 3KENA 4PK4A 2X51A 3LREA 3L1CA 1F9WA 4A14A 4A28A 1I5SA 4A5YA 2ZFLA 2FL2A 3ZFCA 1VFZA 3BFNA 4GKRA 1D1CA 1VFXA 2X2RA 5LT1A 4Y05A 1D0ZA 1V8JA 4PFPA 2GRYA 3T0QA 4BN2A 5HLEA 2MYSA 1LKXA 1BR1A 3HQDA 4E7ZA 2Q2ZA 3CNZA 1II6A 2ZFKA 1MMNA 1D1BA 1V8KA 1Q0BA 1N6MA 1SDMA 2ZFIA 1KK7A 3NWNA 1BR4A 4HNAK 3WPNA 5LT0A 4BXNA 2VASA 3U06A 4PFOA 5LT3A 1VFVA 1GOJA 3COBA 4UBFA 1FMWA 2Q2YA 2ZFMA 4A1ZA 1I6IA 1G8XA 2KINA 2X7DA 5GSZA 1F9TA 2VB6A 4PJJA 3B6UA 4AP0A 2WOGA 3ZFDA 2HEHA 4B7BA 2FL6A 4BBGA 4ETPA 4ZHIA 1MMAA 4ANJA 2XAEA 1MNEA 4A50A 1BG2A 1X88A 5LT4A 2V26A 1VFWA 3GBJA 4LNUK 2OWMA 3K5EA 3CJOA 2GM1A 3KINA 3DCBA 4H1GA 4A51A 3DC4A 4AS7A 1RY6A 2PG2A 4ZCAA 2IEHA 2ZFJA 1FMVA 2X7EA 1MMGA 1MKJA 2Y5WA 3B6VA 4DBQA 3PXNA 4DBRA 2G1QA 2NCDA 2FMEA 2X7CA 1CZ7A 5LT2A 2VVGA 4PJNA 4PJMA 3WRDA 2Y65A 3H4SA 1F9VA 1D0YA 3X2TA 3K3BA 4FRZA 1BR2A 3ZCWA 4E7SA 1LVKA 2UYIA 1F9UA 1MMDA 1T5CA 4PJLA 3L9HA 1D1AA 2UYMA
chains in the Genus database with same CATH superfamily
2XT3A 1D0XA 3KARA 1YRSA 1VOMA 2FKYA 3KENA 4PK4A 2X51A 3LREA 3L1CA 1F9WA 4A14A 4A28A 1I5SA 4A5YA 2ZFLA 2FL2A 3ZFCA 1VFZA 3BFNA 4GKRA 1D1CA 1VFXA 2X2RA 5LT1A 4Y05A 1D0ZA 1V8JA 4PFPA 2GRYA 3T0QA 4BN2A 5HLEA 2MYSA 1LKXA 1BR1A 3HQDA 4E7ZA 2Q2ZA 3CNZA 1II6A 2ZFKA 1MMNA 1D1BA 1V8KA 1Q0BA 4GKPA 1N6MA 1SDMA 2ZFIA 1KK7A 3NWNA 1BR4A 4HNAK 3WPNA 5LT0A 4BXNA 2VASA 3U06A 4PFOA 5LT3A 1VFVA 1GOJA 3COBA 4UBFA 1FMWA 2Q2YA 2ZFMA 4A1ZA 1I6IA 1G8XA 2KINA 2X7DA 5GSZA 1F9TA 2VB6A 4PJJA 3B6UA 4AP0A 2WOGA 3ZFDA 2HEHA 4B7BA 2FL6A 4BBGA 4ETPA 4ZHIA 1MMAA 4ANJA 2XAEA 1MNEA 4A50A 1BG2A 1X88A 5LT4A 2V26A 1VFWA 3GBJA 4LNUK 2OWMA 3K5EA 3CJOA 2GM1A 3KINA 3DCBA 4H1GA 4A51A 3DC4A 4AS7A 1RY6A 2PG2A 4ZCAA 2O0AA 4GKQA 2IEHA 2ZFJA 1FMVA 2X7EA 1MMGA 1MKJA 2Y5WA 3B6VA 4DBQA 4ETPB 3PXNA 4DBRA 2G1QA 2NCDA 2FMEA 2X7CA 1CZ7A 5LT2A 2VVGA 4PJNA 4PJMA 3WRDA 2Y65A 3H4SA 1F9VA 1D0YA 3X2TA 3K3BA 4FRZA 1BR2A 3ZCWA 4E7SA 1LVKA 2UYIA 1F9UA 1MMDA 1T5CA 4PJLA 3L9HA 1D1AA 2UYMA
chains in the Genus database with same CATH topology
2XT3A 1D0XA 3KARA 1YRSA 1VOMA 2FKYA 3KENA 4PK4A 2X51A 3LREA 3L1CA 1F9WA 4A14A 4A28A 1I5SA 4A5YA 2ZFLA 2FL2A 3ZFCA 1VFZA 3BFNA 4GKRA 1D1CA 1VFXA 2X2RA 5LT1A 4Y05A 1D0ZA 1V8JA 4PFPA 2GRYA 3T0QA 4BN2A 5HLEA 2MYSA 1LKXA 1BR1A 3HQDA 4E7ZA 2Q2ZA 3CNZA 1II6A 2ZFKA 1MMNA 1D1BA 1V8KA 1Q0BA 1N6MA 1SDMA 2ZFIA 1KK7A 3NWNA 1BR4A 4HNAK 3WPNA 5LT0A 4BXNA 2VASA 3U06A 4PFOA 5LT3A 1VFVA 1GOJA 3COBA 4UBFA 1FMWA 2Q2YA 2ZFMA 4A1ZA 1I6IA 1G8XA 2KINA 2X7DA 5GSZA 1F9TA 2VB6A 4PJJA 3B6UA 4AP0A 2WOGA 3ZFDA 2HEHA 4B7BA 2FL6A 4BBGA 4ETPA 4ZHIA 1MMAA 4ANJA 2XAEA 1MNEA 4A50A 1BG2A 1X88A 5LT4A 2V26A 1VFWA 3GBJA 4LNUK 2OWMA 3K5EA 3CJOA 2GM1A 3KINA 3DCBA 4H1GA 4A51A 3DC4A 4AS7A 1RY6A 2PG2A 4ZCAA 2IEHA 2ZFJA 1FMVA 2X7EA 1MMGA 1MKJA 2Y5WA 3B6VA 4DBQA 3PXNA 4DBRA 2G1QA 2NCDA 2FMEA 2X7CA 1CZ7A 5LT2A 2VVGA 4PJNA 4PJMA 3WRDA 2Y65A 3H4SA 1F9VA 1D0YA 3X2TA 3K3BA 4FRZA 1BR2A 3ZCWA 4E7SA 1LVKA 2UYIA 1F9UA 1MMDA 1T5CA 4PJLA 3L9HA 1D1AA 2UYMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XT3 A;  1D0X A;  3KAR A;  1YRS A;  1VOM A;  2FKY A;  3KEN A;  4PK4 A;  2X51 A;  3LRE A;  3L1C A;  1F9W A;  4A14 A;  4A28 A;  1I5S A;  4A5Y A;  2ZFL A;  2FL2 A;  3ZFC A;  1VFZ A;  3BFN A;  4GKR A;  1D1C A;  1VFX A;  2X2R A;  5LT1 A;  4Y05 A;  1D0Z A;  1V8J A;  4PFP A;  2GRY A;  3T0Q A;  4BN2 A;  5HLE A;  2MYS A;  1LKX A;  1BR1 A;  3HQD A;  4E7Z A;  2Q2Z A;  3CNZ A;  1II6 A;  2ZFK A;  1MMN A;  1D1B A;  1V8K A;  1Q0B A;  1N6M A;  1SDM A;  2ZFI A;  1KK7 A;  3NWN A;  1BR4 A;  4HNA K;  3WPN A;  5LT0 A;  4BXN A;  2VAS A;  3U06 A;  4PFO A;  5LT3 A;  1VFV A;  1GOJ A;  3COB A;  4UBF A;  1FMW A;  2Q2Y A;  2ZFM A;  4A1Z A;  1I6I A;  1G8X A;  2KIN A;  2X7D A;  5GSZ A;  1F9T A;  2VB6 A;  4PJJ A;  3B6U A;  4AP0 A;  2WOG A;  3ZFD A;  2HEH A;  4B7B A;  2FL6 A;  4BBG A;  4ETP A;  4ZHI A;  1MMA A;  4ANJ A;  2XAE A;  1MNE A;  4A50 A;  1BG2 A;  1X88 A;  5LT4 A;  2V26 A;  1VFW A;  3GBJ A;  4LNU K;  2OWM A;  3K5E A;  3CJO A;  2GM1 A;  3KIN A;  3DCB A;  4H1G A;  4A51 A;  3DC4 A;  4AS7 A;  1RY6 A;  2PG2 A;  4ZCA A;  2IEH A;  2ZFJ A;  1FMV A;  2X7E A;  1MMG A;  1MKJ A;  2Y5W A;  3B6V A;  4DBQ A;  3PXN A;  4DBR A;  2G1Q A;  2NCD A;  2FME A;  2X7C A;  1CZ7 A;  5LT2 A;  2VVG A;  4PJN A;  4PJM A;  3WRD A;  2Y65 A;  3H4S A;  1F9V A;  1D0Y A;  3X2T A;  3K3B A;  4FRZ A;  1BR2 A;  3ZCW A;  4E7S A;  1LVK A;  2UYI A;  1F9U A;  1MMD A;  1T5C A;  4PJL A;  3L9H A;  1D1A A;  2UYM A; 
#chains in the Genus database with same CATH topology
 2XT3 A;  1D0X A;  3KAR A;  1YRS A;  1VOM A;  2FKY A;  3KEN A;  4PK4 A;  2X51 A;  3LRE A;  3L1C A;  1F9W A;  4A14 A;  4A28 A;  1I5S A;  4A5Y A;  2ZFL A;  2FL2 A;  3ZFC A;  1VFZ A;  3BFN A;  4GKR A;  1D1C A;  1VFX A;  2X2R A;  5LT1 A;  4Y05 A;  1D0Z A;  1V8J A;  4PFP A;  2GRY A;  3T0Q A;  4BN2 A;  5HLE A;  2MYS A;  1LKX A;  1BR1 A;  3HQD A;  4E7Z A;  2Q2Z A;  3CNZ A;  1II6 A;  2ZFK A;  1MMN A;  1D1B A;  1V8K A;  1Q0B A;  4GKP A;  1N6M A;  1SDM A;  2ZFI A;  1KK7 A;  3NWN A;  1BR4 A;  4HNA K;  3WPN A;  5LT0 A;  4BXN A;  2VAS A;  3U06 A;  4PFO A;  5LT3 A;  1VFV A;  1GOJ A;  3COB A;  4UBF A;  1FMW A;  2Q2Y A;  2ZFM A;  4A1Z A;  1I6I A;  1G8X A;  2KIN A;  2X7D A;  5GSZ A;  1F9T A;  2VB6 A;  4PJJ A;  3B6U A;  4AP0 A;  2WOG A;  3ZFD A;  2HEH A;  4B7B A;  2FL6 A;  4BBG A;  4ETP A;  4ZHI A;  1MMA A;  4ANJ A;  2XAE A;  1MNE A;  4A50 A;  1BG2 A;  1X88 A;  5LT4 A;  2V26 A;  1VFW A;  3GBJ A;  4LNU K;  2OWM A;  3K5E A;  3CJO A;  2GM1 A;  3KIN A;  3DCB A;  4H1G A;  4A51 A;  3DC4 A;  4AS7 A;  1RY6 A;  2PG2 A;  4ZCA A;  2O0A A;  4GKQ A;  2IEH A;  2ZFJ A;  1FMV A;  2X7E A;  1MMG A;  1MKJ A;  2Y5W A;  3B6V A;  4DBQ A;  4ETP B;  3PXN A;  4DBR A;  2G1Q A;  2NCD A;  2FME A;  2X7C A;  1CZ7 A;  5LT2 A;  2VVG A;  4PJN A;  4PJM A;  3WRD A;  2Y65 A;  3H4S A;  1F9V A;  1D0Y A;  3X2T A;  3K3B A;  4FRZ A;  1BR2 A;  3ZCW A;  4E7S A;  1LVK A;  2UYI A;  1F9U A;  1MMD A;  1T5C A;  4PJL A;  3L9H A;  1D1A A;  2UYM A; 
#chains in the Genus database with same CATH homology
 2XT3 A;  1D0X A;  3KAR A;  1YRS A;  1VOM A;  2FKY A;  3KEN A;  4PK4 A;  2X51 A;  3LRE A;  3L1C A;  1F9W A;  4A14 A;  4A28 A;  1I5S A;  4A5Y A;  2ZFL A;  2FL2 A;  3ZFC A;  1VFZ A;  3BFN A;  4GKR A;  1D1C A;  1VFX A;  2X2R A;  5LT1 A;  4Y05 A;  1D0Z A;  1V8J A;  4PFP A;  2GRY A;  3T0Q A;  4BN2 A;  5HLE A;  2MYS A;  1LKX A;  1BR1 A;  3HQD A;  4E7Z A;  2Q2Z A;  3CNZ A;  1II6 A;  2ZFK A;  1MMN A;  1D1B A;  1V8K A;  1Q0B A;  1N6M A;  1SDM A;  2ZFI A;  1KK7 A;  3NWN A;  1BR4 A;  4HNA K;  3WPN A;  5LT0 A;  4BXN A;  2VAS A;  3U06 A;  4PFO A;  5LT3 A;  1VFV A;  1GOJ A;  3COB A;  4UBF A;  1FMW A;  2Q2Y A;  2ZFM A;  4A1Z A;  1I6I A;  1G8X A;  2KIN A;  2X7D A;  5GSZ A;  1F9T A;  2VB6 A;  4PJJ A;  3B6U A;  4AP0 A;  2WOG A;  3ZFD A;  2HEH A;  4B7B A;  2FL6 A;  4BBG A;  4ETP A;  4ZHI A;  1MMA A;  4ANJ A;  2XAE A;  1MNE A;  4A50 A;  1BG2 A;  1X88 A;  5LT4 A;  2V26 A;  1VFW A;  3GBJ A;  4LNU K;  2OWM A;  3K5E A;  3CJO A;  2GM1 A;  3KIN A;  3DCB A;  4H1G A;  4A51 A;  3DC4 A;  4AS7 A;  1RY6 A;  2PG2 A;  4ZCA A;  2IEH A;  2ZFJ A;  1FMV A;  2X7E A;  1MMG A;  1MKJ A;  2Y5W A;  3B6V A;  4DBQ A;  3PXN A;  4DBR A;  2G1Q A;  2NCD A;  2FME A;  2X7C A;  1CZ7 A;  5LT2 A;  2VVG A;  4PJN A;  4PJM A;  3WRD A;  2Y65 A;  3H4S A;  1F9V A;  1D0Y A;  3X2T A;  3K3B A;  4FRZ A;  1BR2 A;  3ZCW A;  4E7S A;  1LVK A;  2UYI A;  1F9U A;  1MMD A;  1T5C A;  4PJL A;  3L9H A;  1D1A A;  2UYM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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