3U06A

Crystal structure of the kinesin-14 ncdg347d
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
381
structure length
359
Chain Sequence
MHAALSTEVVHLRQRTEELLRCNEQQAAELETCKEQLFQSNMERKELHNTVMDLRDNIRVFCRIRPPLESEENRMCCTWTYHDESTVELQSIDGQQIFSFDQVFHPLSSQSDIFEMVSPLIQSALDGYNICIFAYGQTGSGKTYTMDGVPESVGVIPRTVDLLFDSIRGYRNLGWEYEIKATFLEIYNEVLYDLLSNEQKDMEIRMAKNNKNDIYVSNITEETVLDPNHLRHLMHTAKMNRAGNERSSRSHAVTKLELIGRHAEKQEISVGSINLVDLAGSESKNINRSLSELTNVILALLQKQDHIPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQDCFQESVKSLRFAASVNSCKM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Neck-motor interactions trigger rotation of the kinesin stalk.
pubmed doi rcsb
molecule tags Motor protein
source organism Drosophila melanogaster
molecule keywords Protein claret segregational
total genus 121
structure length 359
sequence length 381
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-09-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 3u06A00
1LVKA 3WRDA 1KK7A 1BG2A 2ZFMA 1V8KA 1MNEA 4PK4A 1X88A 1I6IA 4LNUK 3K3BA 1D0ZA 2X2RA 3COBA 5LT3A 2GM1A 4PFPA 2XAEA 3HQDA 2Q2YA 4E7SA 4ZCAA 1MMNA 4PJLA 1F9UA 3L9HA 2GRYA 1BR1A 2Q2ZA 2X7CA 2KINA 2VB6A 3U06A 5HLEA 1F9TA 2FL2A 3BFNA 3K5EA 4ETPA 4BXNA 1MMDA 4DBQA 5GSZA 4A14A 1YRSA 3ZCWA 4AS7A 1T5CA 2ZFLA 4AP0A 3L1CA 4BBGA 4A5YA 3KINA 4PFOA 2X7EA 2Y65A 4ZHIA 1VFVA 2HEHA 1FMWA 4PJMA 2OWMA 4PJJA 3KENA 3CNZA 1GOJA 4GKRA 1MMAA 1Q0BA 1RY6A 1SDMA 3ZFDA 5LT1A 4BN2A 1BR4A 1VFZA 4E7ZA 2NCDA 1CZ7A 1V8JA 1FMVA 4A50A 1I5SA 2V26A 2ZFJA 2ZFIA 4ANJA 3WPNA 1N6MA 3CJOA 1D0YA 3DCBA 3B6VA 2X51A 4H1GA 1LKXA 2PG2A 2UYIA 5LT2A 3PXNA 2VASA 3LREA 3DC4A 2FL6A 2UYMA 4DBRA 2FKYA 3X2TA 1BR2A 1VFXA 1D0XA 2ZFKA 4A1ZA 3NWNA 4PJNA 1G8XA 1VFWA 3B6UA 3T0QA 2IEHA 4A51A 1MKJA 1F9WA 1II6A 2Y5WA 1F9VA 1MMGA 2X7DA 3KARA 1D1AA 2MYSA 4HNAK 3GBJA 1VOMA 2WOGA 4Y05A 2FMEA 2VVGA 2XT3A 1D1BA 2G1QA 1D1CA 5LT0A 3H4SA 4B7BA 4A28A 4FRZA 5LT4A 3ZFCA 4UBFA
chains in the Genus database with same CATH superfamily
1LVKA 3WRDA 1KK7A 1BG2A 2ZFMA 1V8KA 1MNEA 4PK4A 1X88A 1I6IA 4LNUK 3K3BA 1D0ZA 2X2RA 3COBA 5LT3A 2GM1A 4PFPA 2XAEA 3HQDA 2Q2YA 4E7SA 4ZCAA 1MMNA 4PJLA 1F9UA 3L9HA 2GRYA 1BR1A 2Q2ZA 2X7CA 4GKPA 2KINA 2VB6A 3U06A 5HLEA 1F9TA 2FL2A 3BFNA 3K5EA 4ETPA 4BXNA 1MMDA 4DBQA 5GSZA 4A14A 1YRSA 3ZCWA 4AS7A 1T5CA 2ZFLA 4AP0A 3L1CA 4BBGA 4A5YA 3KINA 4PFOA 2X7EA 2Y65A 4ZHIA 1VFVA 2HEHA 1FMWA 4PJMA 2OWMA 4PJJA 3KENA 3CNZA 1GOJA 4GKRA 1MMAA 1Q0BA 1RY6A 1SDMA 3ZFDA 5LT1A 4BN2A 1BR4A 1VFZA 4E7ZA 2NCDA 1CZ7A 1V8JA 1FMVA 4A50A 1I5SA 2V26A 2ZFJA 2ZFIA 4ANJA 3WPNA 1N6MA 3CJOA 1D0YA 3DCBA 3B6VA 2X51A 4H1GA 1LKXA 2PG2A 2UYIA 5LT2A 3PXNA 2VASA 3LREA 3DC4A 2FL6A 2UYMA 4DBRA 2FKYA 3X2TA 1BR2A 1VFXA 1D0XA 2ZFKA 2O0AA 3NWNA 4A1ZA 4PJNA 1G8XA 1VFWA 3B6UA 3T0QA 2IEHA 4A51A 1MKJA 4GKQA 1F9WA 1II6A 2Y5WA 1F9VA 1MMGA 2X7DA 3KARA 4ETPB 1D1AA 2MYSA 4HNAK 3GBJA 1VOMA 2WOGA 4Y05A 2FMEA 2VVGA 2XT3A 1D1BA 2G1QA 1D1CA 5LT0A 3H4SA 4B7BA 4A28A 4FRZA 5LT4A 3ZFCA 4UBFA
chains in the Genus database with same CATH topology
1LVKA 3WRDA 1KK7A 1BG2A 2ZFMA 1V8KA 1MNEA 4PK4A 1X88A 1I6IA 4LNUK 3K3BA 1D0ZA 2X2RA 3COBA 5LT3A 2GM1A 4PFPA 2XAEA 3HQDA 2Q2YA 4E7SA 4ZCAA 1MMNA 4PJLA 1F9UA 3L9HA 2GRYA 1BR1A 2Q2ZA 2X7CA 2KINA 2VB6A 3U06A 5HLEA 1F9TA 2FL2A 3BFNA 3K5EA 4ETPA 4BXNA 1MMDA 4DBQA 5GSZA 4A14A 1YRSA 3ZCWA 4AS7A 1T5CA 2ZFLA 4AP0A 3L1CA 4BBGA 4A5YA 3KINA 4PFOA 2X7EA 2Y65A 4ZHIA 1VFVA 2HEHA 1FMWA 4PJMA 2OWMA 4PJJA 3KENA 3CNZA 1GOJA 4GKRA 1MMAA 1Q0BA 1RY6A 1SDMA 3ZFDA 5LT1A 4BN2A 1BR4A 1VFZA 4E7ZA 2NCDA 1CZ7A 1V8JA 1FMVA 4A50A 1I5SA 2V26A 2ZFJA 2ZFIA 4ANJA 3WPNA 1N6MA 3CJOA 1D0YA 3DCBA 3B6VA 2X51A 4H1GA 1LKXA 2PG2A 2UYIA 5LT2A 3PXNA 2VASA 3LREA 3DC4A 2FL6A 2UYMA 4DBRA 2FKYA 3X2TA 1BR2A 1VFXA 1D0XA 2ZFKA 4A1ZA 3NWNA 4PJNA 1G8XA 1VFWA 3B6UA 3T0QA 2IEHA 4A51A 1MKJA 1F9WA 1II6A 2Y5WA 1F9VA 1MMGA 2X7DA 3KARA 1D1AA 2MYSA 4HNAK 3GBJA 1VOMA 2WOGA 4Y05A 2FMEA 2VVGA 2XT3A 1D1BA 2G1QA 1D1CA 5LT0A 3H4SA 4B7BA 4A28A 4FRZA 5LT4A 3ZFCA 4UBFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LVK A;  3WRD A;  1KK7 A;  1BG2 A;  2ZFM A;  1V8K A;  1MNE A;  4PK4 A;  1X88 A;  1I6I A;  4LNU K;  3K3B A;  1D0Z A;  2X2R A;  3COB A;  5LT3 A;  2GM1 A;  4PFP A;  2XAE A;  3HQD A;  2Q2Y A;  4E7S A;  4ZCA A;  1MMN A;  4PJL A;  1F9U A;  3L9H A;  2GRY A;  1BR1 A;  2Q2Z A;  2X7C A;  2KIN A;  2VB6 A;  3U06 A;  5HLE A;  1F9T A;  2FL2 A;  3BFN A;  3K5E A;  4ETP A;  4BXN A;  1MMD A;  4DBQ A;  5GSZ A;  4A14 A;  1YRS A;  3ZCW A;  4AS7 A;  1T5C A;  2ZFL A;  4AP0 A;  3L1C A;  4BBG A;  4A5Y A;  3KIN A;  4PFO A;  2X7E A;  2Y65 A;  4ZHI A;  1VFV A;  2HEH A;  1FMW A;  4PJM A;  2OWM A;  4PJJ A;  3KEN A;  3CNZ A;  1GOJ A;  4GKR A;  1MMA A;  1Q0B A;  1RY6 A;  1SDM A;  3ZFD A;  5LT1 A;  4BN2 A;  1BR4 A;  1VFZ A;  4E7Z A;  2NCD A;  1CZ7 A;  1V8J A;  1FMV A;  4A50 A;  1I5S A;  2V26 A;  2ZFJ A;  2ZFI A;  4ANJ A;  3WPN A;  1N6M A;  3CJO A;  1D0Y A;  3DCB A;  3B6V A;  2X51 A;  4H1G A;  1LKX A;  2PG2 A;  2UYI A;  5LT2 A;  3PXN A;  2VAS A;  3LRE A;  3DC4 A;  2FL6 A;  2UYM A;  4DBR A;  2FKY A;  3X2T A;  1BR2 A;  1VFX A;  1D0X A;  2ZFK A;  4A1Z A;  3NWN A;  4PJN A;  1G8X A;  1VFW A;  3B6U A;  3T0Q A;  2IEH A;  4A51 A;  1MKJ A;  1F9W A;  1II6 A;  2Y5W A;  1F9V A;  1MMG A;  2X7D A;  3KAR A;  1D1A A;  2MYS A;  4HNA K;  3GBJ A;  1VOM A;  2WOG A;  4Y05 A;  2FME A;  2VVG A;  2XT3 A;  1D1B A;  2G1Q A;  1D1C A;  5LT0 A;  3H4S A;  4B7B A;  4A28 A;  4FRZ A;  5LT4 A;  3ZFC A;  4UBF A; 
#chains in the Genus database with same CATH topology
 1LVK A;  3WRD A;  1KK7 A;  1BG2 A;  2ZFM A;  1V8K A;  1MNE A;  4PK4 A;  1X88 A;  1I6I A;  4LNU K;  3K3B A;  1D0Z A;  2X2R A;  3COB A;  5LT3 A;  2GM1 A;  4PFP A;  2XAE A;  3HQD A;  2Q2Y A;  4E7S A;  4ZCA A;  1MMN A;  4PJL A;  1F9U A;  3L9H A;  2GRY A;  1BR1 A;  2Q2Z A;  2X7C A;  4GKP A;  2KIN A;  2VB6 A;  3U06 A;  5HLE A;  1F9T A;  2FL2 A;  3BFN A;  3K5E A;  4ETP A;  4BXN A;  1MMD A;  4DBQ A;  5GSZ A;  4A14 A;  1YRS A;  3ZCW A;  4AS7 A;  1T5C A;  2ZFL A;  4AP0 A;  3L1C A;  4BBG A;  4A5Y A;  3KIN A;  4PFO A;  2X7E A;  2Y65 A;  4ZHI A;  1VFV A;  2HEH A;  1FMW A;  4PJM A;  2OWM A;  4PJJ A;  3KEN A;  3CNZ A;  1GOJ A;  4GKR A;  1MMA A;  1Q0B A;  1RY6 A;  1SDM A;  3ZFD A;  5LT1 A;  4BN2 A;  1BR4 A;  1VFZ A;  4E7Z A;  2NCD A;  1CZ7 A;  1V8J A;  1FMV A;  4A50 A;  1I5S A;  2V26 A;  2ZFJ A;  2ZFI A;  4ANJ A;  3WPN A;  1N6M A;  3CJO A;  1D0Y A;  3DCB A;  3B6V A;  2X51 A;  4H1G A;  1LKX A;  2PG2 A;  2UYI A;  5LT2 A;  3PXN A;  2VAS A;  3LRE A;  3DC4 A;  2FL6 A;  2UYM A;  4DBR A;  2FKY A;  3X2T A;  1BR2 A;  1VFX A;  1D0X A;  2ZFK A;  2O0A A;  3NWN A;  4A1Z A;  4PJN A;  1G8X A;  1VFW A;  3B6U A;  3T0Q A;  2IEH A;  4A51 A;  1MKJ A;  4GKQ A;  1F9W A;  1II6 A;  2Y5W A;  1F9V A;  1MMG A;  2X7D A;  3KAR A;  4ETP B;  1D1A A;  2MYS A;  4HNA K;  3GBJ A;  1VOM A;  2WOG A;  4Y05 A;  2FME A;  2VVG A;  2XT3 A;  1D1B A;  2G1Q A;  1D1C A;  5LT0 A;  3H4S A;  4B7B A;  4A28 A;  4FRZ A;  5LT4 A;  3ZFC A;  4UBF A; 
#chains in the Genus database with same CATH homology
 1LVK A;  3WRD A;  1KK7 A;  1BG2 A;  2ZFM A;  1V8K A;  1MNE A;  4PK4 A;  1X88 A;  1I6I A;  4LNU K;  3K3B A;  1D0Z A;  2X2R A;  3COB A;  5LT3 A;  2GM1 A;  4PFP A;  2XAE A;  3HQD A;  2Q2Y A;  4E7S A;  4ZCA A;  1MMN A;  4PJL A;  1F9U A;  3L9H A;  2GRY A;  1BR1 A;  2Q2Z A;  2X7C A;  2KIN A;  2VB6 A;  3U06 A;  5HLE A;  1F9T A;  2FL2 A;  3BFN A;  3K5E A;  4ETP A;  4BXN A;  1MMD A;  4DBQ A;  5GSZ A;  4A14 A;  1YRS A;  3ZCW A;  4AS7 A;  1T5C A;  2ZFL A;  4AP0 A;  3L1C A;  4BBG A;  4A5Y A;  3KIN A;  4PFO A;  2X7E A;  2Y65 A;  4ZHI A;  1VFV A;  2HEH A;  1FMW A;  4PJM A;  2OWM A;  4PJJ A;  3KEN A;  3CNZ A;  1GOJ A;  4GKR A;  1MMA A;  1Q0B A;  1RY6 A;  1SDM A;  3ZFD A;  5LT1 A;  4BN2 A;  1BR4 A;  1VFZ A;  4E7Z A;  2NCD A;  1CZ7 A;  1V8J A;  1FMV A;  4A50 A;  1I5S A;  2V26 A;  2ZFJ A;  2ZFI A;  4ANJ A;  3WPN A;  1N6M A;  3CJO A;  1D0Y A;  3DCB A;  3B6V A;  2X51 A;  4H1G A;  1LKX A;  2PG2 A;  2UYI A;  5LT2 A;  3PXN A;  2VAS A;  3LRE A;  3DC4 A;  2FL6 A;  2UYM A;  4DBR A;  2FKY A;  3X2T A;  1BR2 A;  1VFX A;  1D0X A;  2ZFK A;  4A1Z A;  3NWN A;  4PJN A;  1G8X A;  1VFW A;  3B6U A;  3T0Q A;  2IEH A;  4A51 A;  1MKJ A;  1F9W A;  1II6 A;  2Y5W A;  1F9V A;  1MMG A;  2X7D A;  3KAR A;  1D1A A;  2MYS A;  4HNA K;  3GBJ A;  1VOM A;  2WOG A;  4Y05 A;  2FME A;  2VVG A;  2XT3 A;  1D1B A;  2G1Q A;  1D1C A;  5LT0 A;  3H4S A;  4B7B A;  4A28 A;  4FRZ A;  5LT4 A;  3ZFC A;  4UBF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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