3WRDA

Crystal structure of the kif5c motor domain without any nucleotide
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
330
structure length
310
Chain Sequence
AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKKSLSALGNVISALAEKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding
pubmed doi rcsb
molecule tags Motor protein
source organism Mus musculus
molecule keywords Kinesin heavy chain isoform 5C
total genus 77
structure length 310
sequence length 330
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-02-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 3wrdA00
2X2RA 2KINA 1LKXA 1VFWA 1YRSA 2G1QA 2Q2ZA 4A28A 3LREA 4PJJA 1VFXA 2GRYA 1N6MA 3NWNA 3KINA 1F9VA 2XT3A 4FRZA 1SDMA 2IEHA 3H4SA 1MMGA 3HQDA 4ANJA 1MKJA 4PFOA 1MMDA 1BR2A 1D0ZA 1X88A 4BN2A 1D1AA 1D0YA 4E7SA 2NCDA 4Y05A 2WOGA 4ZCAA 3WPNA 1T5CA 2Y5WA 2GM1A 3L9HA 5LT3A 3ZFCA 4H1GA 2FL2A 2HEHA 3L1CA 4PFPA 4PJLA 1CZ7A 1VFVA 4A50A 4DBRA 2VASA 1G8XA 1V8JA 3WRDA 1BG2A 2FL6A 3KARA 1FMVA 1Q0BA 1MMNA 2UYMA 1F9UA 2X7DA 3KENA 3ZCWA 4B7BA 2V26A 4HNAK 1V8KA 2ZFKA 4A5YA 4A51A 2VVGA 5LT1A 3K3BA 2OWMA 2UYIA 2FMEA 2ZFMA 1F9WA 4E7ZA 3U06A 4ETPA 3DCBA 5LT0A 2XAEA 1GOJA 4ZHIA 2Y65A 5LT4A 2Q2YA 1MNEA 4LNUK 2X7CA 1VOMA 4A1ZA 3BFNA 4PJNA 1MMAA 5GSZA 2ZFIA 4A14A 1II6A 4PJMA 5HLEA 1BR1A 3CNZA 1D0XA 2X7EA 2ZFJA 4PK4A 2VB6A 4AS7A 1LVKA 3COBA 3GBJA 2PG2A 2X51A 1D1CA 2FKYA 2MYSA 5LT2A 1KK7A 2ZFLA 1BR4A 1RY6A 1I6IA 3T0QA 4BXNA 3PXNA 3ZFDA 3B6VA 4BBGA 4GKRA 1FMWA 4UBFA 4DBQA 1I5SA 4AP0A 3K5EA 3CJOA 3DC4A 1VFZA 3X2TA 3B6UA 1D1BA 1F9TA
chains in the Genus database with same CATH superfamily
2X2RA 2KINA 1LKXA 1VFWA 1YRSA 2G1QA 2Q2ZA 4A28A 3LREA 4PJJA 1VFXA 2GRYA 1N6MA 3NWNA 3KINA 1F9VA 2XT3A 4FRZA 1SDMA 2IEHA 3H4SA 1MMGA 3HQDA 4ANJA 1MKJA 4PFOA 1MMDA 1BR2A 1D0ZA 1X88A 4BN2A 1D1AA 1D0YA 4E7SA 2NCDA 4Y05A 2WOGA 4ZCAA 3WPNA 1T5CA 2Y5WA 2GM1A 3L9HA 5LT3A 3ZFCA 4H1GA 2FL2A 2HEHA 3L1CA 4PFPA 4PJLA 1CZ7A 1VFVA 4A50A 4DBRA 4GKQA 2VASA 1G8XA 1V8JA 3WRDA 1BG2A 2FL6A 3KARA 1FMVA 1Q0BA 1MMNA 2UYMA 1F9UA 2X7DA 3KENA 3ZCWA 4B7BA 2V26A 4HNAK 1V8KA 2ZFKA 4A5YA 4A51A 2VVGA 5LT1A 3K3BA 2OWMA 2UYIA 2FMEA 2ZFMA 1F9WA 4E7ZA 3U06A 4ETPA 3DCBA 5LT0A 2XAEA 1GOJA 4ZHIA 2Y65A 5LT4A 2Q2YA 1MNEA 4LNUK 2X7CA 1VOMA 4A1ZA 3BFNA 4PJNA 1MMAA 5GSZA 2ZFIA 2O0AA 4A14A 1II6A 4PJMA 5HLEA 1BR1A 3CNZA 1D0XA 2X7EA 2ZFJA 4PK4A 2VB6A 4AS7A 1LVKA 3COBA 3GBJA 4GKPA 2PG2A 2X51A 1D1CA 2FKYA 2MYSA 5LT2A 1KK7A 2ZFLA 1BR4A 1RY6A 1I6IA 3T0QA 4BXNA 4ETPB 3PXNA 3ZFDA 3B6VA 4BBGA 4GKRA 1FMWA 4UBFA 4DBQA 1I5SA 4AP0A 3K5EA 3CJOA 3DC4A 1VFZA 3X2TA 3B6UA 1D1BA 1F9TA
chains in the Genus database with same CATH topology
2X2RA 2KINA 1LKXA 1VFWA 1YRSA 2G1QA 2Q2ZA 4A28A 3LREA 4PJJA 1VFXA 2GRYA 1N6MA 3NWNA 3KINA 1F9VA 2XT3A 4FRZA 1SDMA 2IEHA 3H4SA 1MMGA 3HQDA 4ANJA 1MKJA 4PFOA 1MMDA 1BR2A 1D0ZA 1X88A 4BN2A 1D1AA 1D0YA 4E7SA 2NCDA 4Y05A 2WOGA 4ZCAA 3WPNA 1T5CA 2Y5WA 2GM1A 3L9HA 5LT3A 3ZFCA 4H1GA 2FL2A 2HEHA 3L1CA 4PFPA 4PJLA 1CZ7A 1VFVA 4A50A 4DBRA 2VASA 1G8XA 1V8JA 3WRDA 1BG2A 2FL6A 3KARA 1FMVA 1Q0BA 1MMNA 2UYMA 1F9UA 2X7DA 3KENA 3ZCWA 4B7BA 2V26A 4HNAK 1V8KA 2ZFKA 4A5YA 4A51A 2VVGA 5LT1A 3K3BA 2OWMA 2UYIA 2FMEA 2ZFMA 1F9WA 4E7ZA 3U06A 4ETPA 3DCBA 5LT0A 2XAEA 1GOJA 4ZHIA 2Y65A 5LT4A 2Q2YA 1MNEA 4LNUK 2X7CA 1VOMA 4A1ZA 3BFNA 4PJNA 1MMAA 5GSZA 2ZFIA 4A14A 1II6A 4PJMA 5HLEA 1BR1A 3CNZA 1D0XA 2X7EA 2ZFJA 4PK4A 2VB6A 4AS7A 1LVKA 3COBA 3GBJA 2PG2A 2X51A 1D1CA 2FKYA 2MYSA 5LT2A 1KK7A 2ZFLA 1BR4A 1RY6A 1I6IA 3T0QA 4BXNA 3PXNA 3ZFDA 3B6VA 4BBGA 4GKRA 1FMWA 4UBFA 4DBQA 1I5SA 4AP0A 3K5EA 3CJOA 3DC4A 1VFZA 3X2TA 3B6UA 1D1BA 1F9TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X2R A;  2KIN A;  1LKX A;  1VFW A;  1YRS A;  2G1Q A;  2Q2Z A;  4A28 A;  3LRE A;  4PJJ A;  1VFX A;  2GRY A;  1N6M A;  3NWN A;  3KIN A;  1F9V A;  2XT3 A;  4FRZ A;  1SDM A;  2IEH A;  3H4S A;  1MMG A;  3HQD A;  4ANJ A;  1MKJ A;  4PFO A;  1MMD A;  1BR2 A;  1D0Z A;  1X88 A;  4BN2 A;  1D1A A;  1D0Y A;  4E7S A;  2NCD A;  4Y05 A;  2WOG A;  4ZCA A;  3WPN A;  1T5C A;  2Y5W A;  2GM1 A;  3L9H A;  5LT3 A;  3ZFC A;  4H1G A;  2FL2 A;  2HEH A;  3L1C A;  4PFP A;  4PJL A;  1CZ7 A;  1VFV A;  4A50 A;  4DBR A;  2VAS A;  1G8X A;  1V8J A;  3WRD A;  1BG2 A;  2FL6 A;  3KAR A;  1FMV A;  1Q0B A;  1MMN A;  2UYM A;  1F9U A;  2X7D A;  3KEN A;  3ZCW A;  4B7B A;  2V26 A;  4HNA K;  1V8K A;  2ZFK A;  4A5Y A;  4A51 A;  2VVG A;  5LT1 A;  3K3B A;  2OWM A;  2UYI A;  2FME A;  2ZFM A;  1F9W A;  4E7Z A;  3U06 A;  4ETP A;  3DCB A;  5LT0 A;  2XAE A;  1GOJ A;  4ZHI A;  2Y65 A;  5LT4 A;  2Q2Y A;  1MNE A;  4LNU K;  2X7C A;  1VOM A;  4A1Z A;  3BFN A;  4PJN A;  1MMA A;  5GSZ A;  2ZFI A;  4A14 A;  1II6 A;  4PJM A;  5HLE A;  1BR1 A;  3CNZ A;  1D0X A;  2X7E A;  2ZFJ A;  4PK4 A;  2VB6 A;  4AS7 A;  1LVK A;  3COB A;  3GBJ A;  2PG2 A;  2X51 A;  1D1C A;  2FKY A;  2MYS A;  5LT2 A;  1KK7 A;  2ZFL A;  1BR4 A;  1RY6 A;  1I6I A;  3T0Q A;  4BXN A;  3PXN A;  3ZFD A;  3B6V A;  4BBG A;  4GKR A;  1FMW A;  4UBF A;  4DBQ A;  1I5S A;  4AP0 A;  3K5E A;  3CJO A;  3DC4 A;  1VFZ A;  3X2T A;  3B6U A;  1D1B A;  1F9T A; 
#chains in the Genus database with same CATH topology
 2X2R A;  2KIN A;  1LKX A;  1VFW A;  1YRS A;  2G1Q A;  2Q2Z A;  4A28 A;  3LRE A;  4PJJ A;  1VFX A;  2GRY A;  1N6M A;  3NWN A;  3KIN A;  1F9V A;  2XT3 A;  4FRZ A;  1SDM A;  2IEH A;  3H4S A;  1MMG A;  3HQD A;  4ANJ A;  1MKJ A;  4PFO A;  1MMD A;  1BR2 A;  1D0Z A;  1X88 A;  4BN2 A;  1D1A A;  1D0Y A;  4E7S A;  2NCD A;  4Y05 A;  2WOG A;  4ZCA A;  3WPN A;  1T5C A;  2Y5W A;  2GM1 A;  3L9H A;  5LT3 A;  3ZFC A;  4H1G A;  2FL2 A;  2HEH A;  3L1C A;  4PFP A;  4PJL A;  1CZ7 A;  1VFV A;  4A50 A;  4DBR A;  4GKQ A;  2VAS A;  1G8X A;  1V8J A;  3WRD A;  1BG2 A;  2FL6 A;  3KAR A;  1FMV A;  1Q0B A;  1MMN A;  2UYM A;  1F9U A;  2X7D A;  3KEN A;  3ZCW A;  4B7B A;  2V26 A;  4HNA K;  1V8K A;  2ZFK A;  4A5Y A;  4A51 A;  2VVG A;  5LT1 A;  3K3B A;  2OWM A;  2UYI A;  2FME A;  2ZFM A;  1F9W A;  4E7Z A;  3U06 A;  4ETP A;  3DCB A;  5LT0 A;  2XAE A;  1GOJ A;  4ZHI A;  2Y65 A;  5LT4 A;  2Q2Y A;  1MNE A;  4LNU K;  2X7C A;  1VOM A;  4A1Z A;  3BFN A;  4PJN A;  1MMA A;  5GSZ A;  2ZFI A;  2O0A A;  4A14 A;  1II6 A;  4PJM A;  5HLE A;  1BR1 A;  3CNZ A;  1D0X A;  2X7E A;  2ZFJ A;  4PK4 A;  2VB6 A;  4AS7 A;  1LVK A;  3COB A;  3GBJ A;  4GKP A;  2PG2 A;  2X51 A;  1D1C A;  2FKY A;  2MYS A;  5LT2 A;  1KK7 A;  2ZFL A;  1BR4 A;  1RY6 A;  1I6I A;  3T0Q A;  4BXN A;  4ETP B;  3PXN A;  3ZFD A;  3B6V A;  4BBG A;  4GKR A;  1FMW A;  4UBF A;  4DBQ A;  1I5S A;  4AP0 A;  3K5E A;  3CJO A;  3DC4 A;  1VFZ A;  3X2T A;  3B6U A;  1D1B A;  1F9T A; 
#chains in the Genus database with same CATH homology
 2X2R A;  2KIN A;  1LKX A;  1VFW A;  1YRS A;  2G1Q A;  2Q2Z A;  4A28 A;  3LRE A;  4PJJ A;  1VFX A;  2GRY A;  1N6M A;  3NWN A;  3KIN A;  1F9V A;  2XT3 A;  4FRZ A;  1SDM A;  2IEH A;  3H4S A;  1MMG A;  3HQD A;  4ANJ A;  1MKJ A;  4PFO A;  1MMD A;  1BR2 A;  1D0Z A;  1X88 A;  4BN2 A;  1D1A A;  1D0Y A;  4E7S A;  2NCD A;  4Y05 A;  2WOG A;  4ZCA A;  3WPN A;  1T5C A;  2Y5W A;  2GM1 A;  3L9H A;  5LT3 A;  3ZFC A;  4H1G A;  2FL2 A;  2HEH A;  3L1C A;  4PFP A;  4PJL A;  1CZ7 A;  1VFV A;  4A50 A;  4DBR A;  2VAS A;  1G8X A;  1V8J A;  3WRD A;  1BG2 A;  2FL6 A;  3KAR A;  1FMV A;  1Q0B A;  1MMN A;  2UYM A;  1F9U A;  2X7D A;  3KEN A;  3ZCW A;  4B7B A;  2V26 A;  4HNA K;  1V8K A;  2ZFK A;  4A5Y A;  4A51 A;  2VVG A;  5LT1 A;  3K3B A;  2OWM A;  2UYI A;  2FME A;  2ZFM A;  1F9W A;  4E7Z A;  3U06 A;  4ETP A;  3DCB A;  5LT0 A;  2XAE A;  1GOJ A;  4ZHI A;  2Y65 A;  5LT4 A;  2Q2Y A;  1MNE A;  4LNU K;  2X7C A;  1VOM A;  4A1Z A;  3BFN A;  4PJN A;  1MMA A;  5GSZ A;  2ZFI A;  4A14 A;  1II6 A;  4PJM A;  5HLE A;  1BR1 A;  3CNZ A;  1D0X A;  2X7E A;  2ZFJ A;  4PK4 A;  2VB6 A;  4AS7 A;  1LVK A;  3COB A;  3GBJ A;  2PG2 A;  2X51 A;  1D1C A;  2FKY A;  2MYS A;  5LT2 A;  1KK7 A;  2ZFL A;  1BR4 A;  1RY6 A;  1I6I A;  3T0Q A;  4BXN A;  3PXN A;  3ZFD A;  3B6V A;  4BBG A;  4GKR A;  1FMW A;  4UBF A;  4DBQ A;  1I5S A;  4AP0 A;  3K5E A;  3CJO A;  3DC4 A;  1VFZ A;  3X2T A;  3B6U A;  1D1B A;  1F9T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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