3WRD | Genus

Total Genus 77

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	77
sequence length	330
structure length	310
Chain Sequence	AECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKKSLSALGNVISALAEKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVN

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Motor protein
source organism	Mus musculus
publication title	X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding pubmed doi rcsb
molecule keywords	Kinesin heavy chain isoform 5C
total genus	77
structure length	310
sequence length	330
chains with identical sequence	B
ec nomenclature
pdb deposition date	2014-02-21

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00225	Kinesin	Kinesin motor domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.850.10	Alpha Beta	3-Layer(aba) Sandwich	Kinesin	Kinesin motor domain	3wrdA00

4ANJA 3KARA 1D1CA 5LT2A 2Q2YA 3LREA 2ZFLA 2IEHA 3KENA 2FL2A 1I5SA 4ZCAA 2ZFMA 2ZFJA 1YRSA 1II6A 1MMDA 2HEHA 3GBJA 1BR1A 5LT1A 2UYIA 1D0XA 1FMVA 1MMGA 4UBFA 2Y5WA 3L1CA 4HNAK 4Y05A 2G1QA 2ZFIA 1BR4A 4PJNA 3U06A 4PFPA 1D1AA 4A50A 4ETPA 1VOMA 1GOJA 4A14A 3BFNA 2X7DA 5LT4A 2GM1A 2VASA 2FKYA 3DC4A 3CJOA 4DBQA 3KINA 3DCBA 3HQDA 2ZFKA 4PK4A 5GSZA 3T0QA 4PFOA 1VFVA 1N6MA 4A51A 3PXNA 4ZHIA 1VFZA 4FRZA 2Q2ZA 2FL6A 4PJMA 3B6UA 2NCDA 1X88A 5LT0A 4B7BA 3B6VA 3COBA 2GRYA 5HLEA 4BBGA 1BR2A 2KINA 1MKJA 2X51A 1VFWA 5LT3A 3ZFCA 2X7EA 2FMEA 2OWMA 2XAEA 3K3BA 1KK7A 1RY6A 1F9VA 1BG2A 1G8XA 4PJLA 2V26A 4AP0A 3H4SA 1Q0BA 3K5EA 1D0YA 4BXNA 4GKRA 1D0ZA 1FMWA 2VB6A 4E7SA 2Y65A 1MMNA 4A28A 2X2RA 1I6IA 1D1BA 2UYMA 1SDMA 1V8JA 2XT3A 2X7CA 4DBRA 1F9UA 4BN2A 4PJJA 2PG2A 1VFXA 4H1GA 3ZCWA 3NWNA 4E7ZA 2VVGA 2WOGA 1MMAA 4A1ZA 2MYSA 3CNZA 3WPNA 3ZFDA 3WRDA 4AS7A 1F9WA 1LVKA 1MNEA 1LKXA 1T5CA 1F9TA 1V8KA 3X2TA 3L9HA 4A5YA 4LNUK 1CZ7A
chains in the Genus database with same CATH superfamily

4ANJA 3KARA 1D1CA 5LT2A 2Q2YA 3LREA 2ZFLA 2IEHA 3KENA 2FL2A 1I5SA 4ZCAA 2ZFMA 2ZFJA 1YRSA 1II6A 1MMDA 2HEHA 3GBJA 1BR1A 5LT1A 2UYIA 1D0XA 1FMVA 1MMGA 4UBFA 2Y5WA 3L1CA 4HNAK 4Y05A 2G1QA 2ZFIA 1BR4A 4PJNA 3U06A 4PFPA 1D1AA 4A50A 4ETPA 1VOMA 1GOJA 4A14A 3BFNA 2X7DA 5LT4A 2GM1A 2VASA 2FKYA 3DC4A 3CJOA 4ETPB 4DBQA 3KINA 3DCBA 3HQDA 4GKPA 2ZFKA 4PK4A 5GSZA 3T0QA 4PFOA 1VFVA 1N6MA 4A51A 3PXNA 4ZHIA 1VFZA 4FRZA 2Q2ZA 2FL6A 4PJMA 3B6UA 2NCDA 1X88A 5LT0A 4B7BA 3B6VA 3COBA 2GRYA 5HLEA 4BBGA 1BR2A 2KINA 1MKJA 2X51A 1VFWA 5LT3A 3ZFCA 2X7EA 2FMEA 2OWMA 2XAEA 3K3BA 1KK7A 1RY6A 1F9VA 1BG2A 1G8XA 4PJLA 2V26A 4AP0A 3H4SA 1Q0BA 3K5EA 1D0YA 4BXNA 4GKRA 1D0ZA 1FMWA 2VB6A 4E7SA 2Y65A 1MMNA 4A28A 2X2RA 1I6IA 1D1BA 2UYMA 1SDMA 1V8JA 2XT3A 2X7CA 4DBRA 2O0AA 1F9UA 4BN2A 4PJJA 2PG2A 1VFXA 4H1GA 3ZCWA 3NWNA 4E7ZA 2VVGA 2WOGA 1MMAA 4A1ZA 2MYSA 3CNZA 3WPNA 4GKQA 3ZFDA 3WRDA 4AS7A 1F9WA 1LVKA 1MNEA 1LKXA 1T5CA 1F9TA 1V8KA 3X2TA 3L9HA 4A5YA 4LNUK 1CZ7A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4ANJ A;  3KAR A;  1D1C A;  5LT2 A;  2Q2Y A;  3LRE A;  2ZFL A;  2IEH A;  3KEN A;  2FL2 A;  1I5S A;  4ZCA A;  2ZFM A;  2ZFJ A;  1YRS A;  1II6 A;  1MMD A;  2HEH A;  3GBJ A;  1BR1 A;  5LT1 A;  2UYI A;  1D0X A;  1FMV A;  1MMG A;  4UBF A;  2Y5W A;  3L1C A;  4HNA K;  4Y05 A;  2G1Q A;  2ZFI A;  1BR4 A;  4PJN A;  3U06 A;  4PFP A;  1D1A A;  4A50 A;  4ETP A;  1VOM A;  1GOJ A;  4A14 A;  3BFN A;  2X7D A;  5LT4 A;  2GM1 A;  2VAS A;  2FKY A;  3DC4 A;  3CJO A;  4DBQ A;  3KIN A;  3DCB A;  3HQD A;  2ZFK A;  4PK4 A;  5GSZ A;  3T0Q A;  4PFO A;  1VFV A;  1N6M A;  4A51 A;  3PXN A;  4ZHI A;  1VFZ A;  4FRZ A;  2Q2Z A;  2FL6 A;  4PJM A;  3B6U A;  2NCD A;  1X88 A;  5LT0 A;  4B7B A;  3B6V A;  3COB A;  2GRY A;  5HLE A;  4BBG A;  1BR2 A;  2KIN A;  1MKJ A;  2X51 A;  1VFW A;  5LT3 A;  3ZFC A;  2X7E A;  2FME A;  2OWM A;  2XAE A;  3K3B A;  1KK7 A;  1RY6 A;  1F9V A;  1BG2 A;  1G8X A;  4PJL A;  2V26 A;  4AP0 A;  3H4S A;  1Q0B A;  3K5E A;  1D0Y A;  4BXN A;  4GKR A;  1D0Z A;  1FMW A;  2VB6 A;  4E7S A;  2Y65 A;  1MMN A;  4A28 A;  2X2R A;  1I6I A;  1D1B A;  2UYM A;  1SDM A;  1V8J A;  2XT3 A;  2X7C A;  4DBR A;  1F9U A;  4BN2 A;  4PJJ A;  2PG2 A;  1VFX A;  4H1G A;  3ZCW A;  3NWN A;  4E7Z A;  2VVG A;  2WOG A;  1MMA A;  4A1Z A;  2MYS A;  3CNZ A;  3WPN A;  3ZFD A;  3WRD A;  4AS7 A;  1F9W A;  1LVK A;  1MNE A;  1LKX A;  1T5C A;  1F9T A;  1V8K A;  3X2T A;  3L9H A;  4A5Y A;  4LNU K;  1CZ7 A; 
#chains in the Genus database with same CATH topology
 4ANJ A;  3KAR A;  1D1C A;  5LT2 A;  2Q2Y A;  3LRE A;  2ZFL A;  2IEH A;  3KEN A;  2FL2 A;  1I5S A;  4ZCA A;  2ZFM A;  2ZFJ A;  1YRS A;  1II6 A;  1MMD A;  2HEH A;  3GBJ A;  1BR1 A;  5LT1 A;  2UYI A;  1D0X A;  1FMV A;  1MMG A;  4UBF A;  2Y5W A;  3L1C A;  4HNA K;  4Y05 A;  2G1Q A;  2ZFI A;  1BR4 A;  4PJN A;  3U06 A;  4PFP A;  1D1A A;  4A50 A;  4ETP A;  1VOM A;  1GOJ A;  4A14 A;  3BFN A;  2X7D A;  5LT4 A;  2GM1 A;  2VAS A;  2FKY A;  3DC4 A;  3CJO A;  4ETP B;  4DBQ A;  3KIN A;  3DCB A;  3HQD A;  4GKP A;  2ZFK A;  4PK4 A;  5GSZ A;  3T0Q A;  4PFO A;  1VFV A;  1N6M A;  4A51 A;  3PXN A;  4ZHI A;  1VFZ A;  4FRZ A;  2Q2Z A;  2FL6 A;  4PJM A;  3B6U A;  2NCD A;  1X88 A;  5LT0 A;  4B7B A;  3B6V A;  3COB A;  2GRY A;  5HLE A;  4BBG A;  1BR2 A;  2KIN A;  1MKJ A;  2X51 A;  1VFW A;  5LT3 A;  3ZFC A;  2X7E A;  2FME A;  2OWM A;  2XAE A;  3K3B A;  1KK7 A;  1RY6 A;  1F9V A;  1BG2 A;  1G8X A;  4PJL A;  2V26 A;  4AP0 A;  3H4S A;  1Q0B A;  3K5E A;  1D0Y A;  4BXN A;  4GKR A;  1D0Z A;  1FMW A;  2VB6 A;  4E7S A;  2Y65 A;  1MMN A;  4A28 A;  2X2R A;  1I6I A;  1D1B A;  2UYM A;  1SDM A;  1V8J A;  2XT3 A;  2X7C A;  4DBR A;  2O0A A;  1F9U A;  4BN2 A;  4PJJ A;  2PG2 A;  1VFX A;  4H1G A;  3ZCW A;  3NWN A;  4E7Z A;  2VVG A;  2WOG A;  1MMA A;  4A1Z A;  2MYS A;  3CNZ A;  3WPN A;  4GKQ A;  3ZFD A;  3WRD A;  4AS7 A;  1F9W A;  1LVK A;  1MNE A;  1LKX A;  1T5C A;  1F9T A;  1V8K A;  3X2T A;  3L9H A;  4A5Y A;  4LNU K;  1CZ7 A; 
#chains in the Genus database with same CATH homology
 4ANJ A;  3KAR A;  1D1C A;  5LT2 A;  2Q2Y A;  3LRE A;  2ZFL A;  2IEH A;  3KEN A;  2FL2 A;  1I5S A;  4ZCA A;  2ZFM A;  2ZFJ A;  1YRS A;  1II6 A;  1MMD A;  2HEH A;  3GBJ A;  1BR1 A;  5LT1 A;  2UYI A;  1D0X A;  1FMV A;  1MMG A;  4UBF A;  2Y5W A;  3L1C A;  4HNA K;  4Y05 A;  2G1Q A;  2ZFI A;  1BR4 A;  4PJN A;  3U06 A;  4PFP A;  1D1A A;  4A50 A;  4ETP A;  1VOM A;  1GOJ A;  4A14 A;  3BFN A;  2X7D A;  5LT4 A;  2GM1 A;  2VAS A;  2FKY A;  3DC4 A;  3CJO A;  4DBQ A;  3KIN A;  3DCB A;  3HQD A;  2ZFK A;  4PK4 A;  5GSZ A;  3T0Q A;  4PFO A;  1VFV A;  1N6M A;  4A51 A;  3PXN A;  4ZHI A;  1VFZ A;  4FRZ A;  2Q2Z A;  2FL6 A;  4PJM A;  3B6U A;  2NCD A;  1X88 A;  5LT0 A;  4B7B A;  3B6V A;  3COB A;  2GRY A;  5HLE A;  4BBG A;  1BR2 A;  2KIN A;  1MKJ A;  2X51 A;  1VFW A;  5LT3 A;  3ZFC A;  2X7E A;  2FME A;  2OWM A;  2XAE A;  3K3B A;  1KK7 A;  1RY6 A;  1F9V A;  1BG2 A;  1G8X A;  4PJL A;  2V26 A;  4AP0 A;  3H4S A;  1Q0B A;  3K5E A;  1D0Y A;  4BXN A;  4GKR A;  1D0Z A;  1FMW A;  2VB6 A;  4E7S A;  2Y65 A;  1MMN A;  4A28 A;  2X2R A;  1I6I A;  1D1B A;  2UYM A;  1SDM A;  1V8J A;  2XT3 A;  2X7C A;  4DBR A;  1F9U A;  4BN2 A;  4PJJ A;  2PG2 A;  1VFX A;  4H1G A;  3ZCW A;  3NWN A;  4E7Z A;  2VVG A;  2WOG A;  1MMA A;  4A1Z A;  2MYS A;  3CNZ A;  3WPN A;  3ZFD A;  3WRD A;  4AS7 A;  1F9W A;  1LVK A;  1MNE A;  1LKX A;  1T5C A;  1F9T A;  1V8K A;  3X2T A;  3L9H A;  4A5Y A;  4LNU K;  1CZ7 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3WRDA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations