3X2TA

Crystal structure of the kif5c motor domain with adp
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
331
structure length
311
Chain Sequence
PAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKNKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding
pubmed doi rcsb
molecule tags Motor protein
source organism Mus musculus
molecule keywords Kinesin heavy chain isoform 5C
total genus 87
structure length 311
sequence length 331
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-01-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 3x2tA00
3L1CA 2G1QA 2ZFLA 1D0ZA 1G8XA 1VFZA 2Q2ZA 4A51A 2VASA 2GRYA 4BXNA 3K3BA 4FRZA 4ZHIA 1D0XA 3X2TA 4E7SA 2XAEA 4DBRA 4BN2A 4A1ZA 1GOJA 3KINA 4A5YA 4H1GA 2Q2YA 2NCDA 2WOGA 3B6VA 2V26A 5LT2A 1RY6A 1LKXA 1FMWA 1D1CA 5LT3A 2Y5WA 5LT0A 1BR2A 1D1AA 1VOMA 4A50A 4E7ZA 4PJNA 5LT4A 4PJMA 1MNEA 4PFPA 3LREA 2ZFJA 4A14A 4BBGA 3WPNA 2FKYA 4ZCAA 3HQDA 2UYIA 3KENA 4ETPA 3L9HA 2Y65A 1BG2A 1I5SA 4GKRA 4PK4A 4AS7A 2UYMA 3DC4A 2X51A 1MMGA 2X2RA 3U06A 3NWNA 5LT1A 3K5EA 4B7BA 2OWMA 1F9WA 1BR4A 1BR1A 2ZFIA 3H4SA 1YRSA 2IEHA 3BFNA 1MMNA 2PG2A 2XT3A 4PJJA 4HNAK 1VFWA 3B6UA 3CJOA 4LNUK 3T0QA 4AP0A 1VFVA 1X88A 4PFOA 1F9UA 1F9VA 4ANJA 1D1BA 2HEHA 3ZCWA 1SDMA 2FMEA 2X7EA 2X7DA 2GM1A 2VB6A 1F9TA 1T5CA 2ZFMA 3PXNA 1I6IA 1MMDA 3DCBA 1D0YA 4DBQA 3CNZA 2FL2A 2VVGA 3KARA 1V8KA 3WRDA 2KINA 1MMAA 1N6MA 2FL6A 3GBJA 4PJLA 3COBA 2MYSA 1V8JA 1VFXA 1CZ7A 1LVKA 4A28A 1KK7A 1Q0BA 1II6A 1MKJA 3ZFDA 1FMVA 4UBFA 4Y05A 5HLEA 3ZFCA 2ZFKA 5GSZA 2X7CA
chains in the Genus database with same CATH superfamily
3L1CA 2G1QA 2ZFLA 1D0ZA 1G8XA 1VFZA 2Q2ZA 4A51A 2VASA 2GRYA 4BXNA 3K3BA 4FRZA 4ZHIA 1D0XA 3X2TA 4E7SA 2XAEA 2O0AA 4DBRA 4BN2A 4A1ZA 1GOJA 3KINA 4A5YA 4H1GA 2Q2YA 2NCDA 2WOGA 3B6VA 2V26A 5LT2A 1RY6A 1LKXA 1FMWA 1D1CA 5LT3A 4ETPB 4GKQA 2Y5WA 5LT0A 1BR2A 1D1AA 1VOMA 4A50A 4E7ZA 4PJNA 5LT4A 4PJMA 1MNEA 4PFPA 3LREA 2ZFJA 4A14A 4GKPA 4BBGA 3WPNA 2FKYA 4ZCAA 3HQDA 2UYIA 3KENA 4ETPA 3L9HA 2Y65A 1BG2A 1I5SA 4GKRA 4PK4A 4AS7A 2UYMA 3DC4A 2X51A 1MMGA 2X2RA 3U06A 3NWNA 5LT1A 3K5EA 4B7BA 2OWMA 1F9WA 1BR4A 1BR1A 2ZFIA 3H4SA 1YRSA 2IEHA 3BFNA 1MMNA 2PG2A 2XT3A 4PJJA 4HNAK 1VFWA 3B6UA 3CJOA 4LNUK 3T0QA 4AP0A 1VFVA 1X88A 4PFOA 1F9UA 1F9VA 4ANJA 1D1BA 2HEHA 3ZCWA 1SDMA 2FMEA 2X7EA 2X7DA 2GM1A 2VB6A 1F9TA 1T5CA 2ZFMA 3PXNA 1I6IA 1MMDA 3DCBA 1D0YA 4DBQA 3CNZA 2FL2A 2VVGA 3KARA 1V8KA 3WRDA 2KINA 1MMAA 1N6MA 2FL6A 3GBJA 4PJLA 3COBA 2MYSA 1V8JA 1VFXA 1CZ7A 1LVKA 4A28A 1KK7A 1Q0BA 1II6A 1MKJA 3ZFDA 1FMVA 4UBFA 4Y05A 5HLEA 3ZFCA 2ZFKA 5GSZA 2X7CA
chains in the Genus database with same CATH topology
3L1CA 2G1QA 2ZFLA 1D0ZA 1G8XA 1VFZA 2Q2ZA 4A51A 2VASA 2GRYA 4BXNA 3K3BA 4FRZA 4ZHIA 1D0XA 3X2TA 4E7SA 2XAEA 4DBRA 4BN2A 4A1ZA 1GOJA 3KINA 4A5YA 4H1GA 2Q2YA 2NCDA 2WOGA 3B6VA 2V26A 5LT2A 1RY6A 1LKXA 1FMWA 1D1CA 5LT3A 2Y5WA 5LT0A 1BR2A 1D1AA 1VOMA 4A50A 4E7ZA 4PJNA 5LT4A 4PJMA 1MNEA 4PFPA 3LREA 2ZFJA 4A14A 4BBGA 3WPNA 2FKYA 4ZCAA 3HQDA 2UYIA 3KENA 4ETPA 3L9HA 2Y65A 1BG2A 1I5SA 4GKRA 4PK4A 4AS7A 2UYMA 3DC4A 2X51A 1MMGA 2X2RA 3U06A 3NWNA 5LT1A 3K5EA 4B7BA 2OWMA 1F9WA 1BR4A 1BR1A 2ZFIA 3H4SA 1YRSA 2IEHA 3BFNA 1MMNA 2PG2A 2XT3A 4PJJA 4HNAK 1VFWA 3B6UA 3CJOA 4LNUK 3T0QA 4AP0A 1VFVA 1X88A 4PFOA 1F9UA 1F9VA 4ANJA 1D1BA 2HEHA 3ZCWA 1SDMA 2FMEA 2X7EA 2X7DA 2GM1A 2VB6A 1F9TA 1T5CA 2ZFMA 3PXNA 1I6IA 1MMDA 3DCBA 1D0YA 4DBQA 3CNZA 2FL2A 2VVGA 3KARA 1V8KA 3WRDA 2KINA 1MMAA 1N6MA 2FL6A 3GBJA 4PJLA 3COBA 2MYSA 1V8JA 1VFXA 1CZ7A 1LVKA 4A28A 1KK7A 1Q0BA 1II6A 1MKJA 3ZFDA 1FMVA 4UBFA 4Y05A 5HLEA 3ZFCA 2ZFKA 5GSZA 2X7CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3L1C A;  2G1Q A;  2ZFL A;  1D0Z A;  1G8X A;  1VFZ A;  2Q2Z A;  4A51 A;  2VAS A;  2GRY A;  4BXN A;  3K3B A;  4FRZ A;  4ZHI A;  1D0X A;  3X2T A;  4E7S A;  2XAE A;  4DBR A;  4BN2 A;  4A1Z A;  1GOJ A;  3KIN A;  4A5Y A;  4H1G A;  2Q2Y A;  2NCD A;  2WOG A;  3B6V A;  2V26 A;  5LT2 A;  1RY6 A;  1LKX A;  1FMW A;  1D1C A;  5LT3 A;  2Y5W A;  5LT0 A;  1BR2 A;  1D1A A;  1VOM A;  4A50 A;  4E7Z A;  4PJN A;  5LT4 A;  4PJM A;  1MNE A;  4PFP A;  3LRE A;  2ZFJ A;  4A14 A;  4BBG A;  3WPN A;  2FKY A;  4ZCA A;  3HQD A;  2UYI A;  3KEN A;  4ETP A;  3L9H A;  2Y65 A;  1BG2 A;  1I5S A;  4GKR A;  4PK4 A;  4AS7 A;  2UYM A;  3DC4 A;  2X51 A;  1MMG A;  2X2R A;  3U06 A;  3NWN A;  5LT1 A;  3K5E A;  4B7B A;  2OWM A;  1F9W A;  1BR4 A;  1BR1 A;  2ZFI A;  3H4S A;  1YRS A;  2IEH A;  3BFN A;  1MMN A;  2PG2 A;  2XT3 A;  4PJJ A;  4HNA K;  1VFW A;  3B6U A;  3CJO A;  4LNU K;  3T0Q A;  4AP0 A;  1VFV A;  1X88 A;  4PFO A;  1F9U A;  1F9V A;  4ANJ A;  1D1B A;  2HEH A;  3ZCW A;  1SDM A;  2FME A;  2X7E A;  2X7D A;  2GM1 A;  2VB6 A;  1F9T A;  1T5C A;  2ZFM A;  3PXN A;  1I6I A;  1MMD A;  3DCB A;  1D0Y A;  4DBQ A;  3CNZ A;  2FL2 A;  2VVG A;  3KAR A;  1V8K A;  3WRD A;  2KIN A;  1MMA A;  1N6M A;  2FL6 A;  3GBJ A;  4PJL A;  3COB A;  2MYS A;  1V8J A;  1VFX A;  1CZ7 A;  1LVK A;  4A28 A;  1KK7 A;  1Q0B A;  1II6 A;  1MKJ A;  3ZFD A;  1FMV A;  4UBF A;  4Y05 A;  5HLE A;  3ZFC A;  2ZFK A;  5GSZ A;  2X7C A; 
#chains in the Genus database with same CATH topology
 3L1C A;  2G1Q A;  2ZFL A;  1D0Z A;  1G8X A;  1VFZ A;  2Q2Z A;  4A51 A;  2VAS A;  2GRY A;  4BXN A;  3K3B A;  4FRZ A;  4ZHI A;  1D0X A;  3X2T A;  4E7S A;  2XAE A;  2O0A A;  4DBR A;  4BN2 A;  4A1Z A;  1GOJ A;  3KIN A;  4A5Y A;  4H1G A;  2Q2Y A;  2NCD A;  2WOG A;  3B6V A;  2V26 A;  5LT2 A;  1RY6 A;  1LKX A;  1FMW A;  1D1C A;  5LT3 A;  4ETP B;  4GKQ A;  2Y5W A;  5LT0 A;  1BR2 A;  1D1A A;  1VOM A;  4A50 A;  4E7Z A;  4PJN A;  5LT4 A;  4PJM A;  1MNE A;  4PFP A;  3LRE A;  2ZFJ A;  4A14 A;  4GKP A;  4BBG A;  3WPN A;  2FKY A;  4ZCA A;  3HQD A;  2UYI A;  3KEN A;  4ETP A;  3L9H A;  2Y65 A;  1BG2 A;  1I5S A;  4GKR A;  4PK4 A;  4AS7 A;  2UYM A;  3DC4 A;  2X51 A;  1MMG A;  2X2R A;  3U06 A;  3NWN A;  5LT1 A;  3K5E A;  4B7B A;  2OWM A;  1F9W A;  1BR4 A;  1BR1 A;  2ZFI A;  3H4S A;  1YRS A;  2IEH A;  3BFN A;  1MMN A;  2PG2 A;  2XT3 A;  4PJJ A;  4HNA K;  1VFW A;  3B6U A;  3CJO A;  4LNU K;  3T0Q A;  4AP0 A;  1VFV A;  1X88 A;  4PFO A;  1F9U A;  1F9V A;  4ANJ A;  1D1B A;  2HEH A;  3ZCW A;  1SDM A;  2FME A;  2X7E A;  2X7D A;  2GM1 A;  2VB6 A;  1F9T A;  1T5C A;  2ZFM A;  3PXN A;  1I6I A;  1MMD A;  3DCB A;  1D0Y A;  4DBQ A;  3CNZ A;  2FL2 A;  2VVG A;  3KAR A;  1V8K A;  3WRD A;  2KIN A;  1MMA A;  1N6M A;  2FL6 A;  3GBJ A;  4PJL A;  3COB A;  2MYS A;  1V8J A;  1VFX A;  1CZ7 A;  1LVK A;  4A28 A;  1KK7 A;  1Q0B A;  1II6 A;  1MKJ A;  3ZFD A;  1FMV A;  4UBF A;  4Y05 A;  5HLE A;  3ZFC A;  2ZFK A;  5GSZ A;  2X7C A; 
#chains in the Genus database with same CATH homology
 3L1C A;  2G1Q A;  2ZFL A;  1D0Z A;  1G8X A;  1VFZ A;  2Q2Z A;  4A51 A;  2VAS A;  2GRY A;  4BXN A;  3K3B A;  4FRZ A;  4ZHI A;  1D0X A;  3X2T A;  4E7S A;  2XAE A;  4DBR A;  4BN2 A;  4A1Z A;  1GOJ A;  3KIN A;  4A5Y A;  4H1G A;  2Q2Y A;  2NCD A;  2WOG A;  3B6V A;  2V26 A;  5LT2 A;  1RY6 A;  1LKX A;  1FMW A;  1D1C A;  5LT3 A;  2Y5W A;  5LT0 A;  1BR2 A;  1D1A A;  1VOM A;  4A50 A;  4E7Z A;  4PJN A;  5LT4 A;  4PJM A;  1MNE A;  4PFP A;  3LRE A;  2ZFJ A;  4A14 A;  4BBG A;  3WPN A;  2FKY A;  4ZCA A;  3HQD A;  2UYI A;  3KEN A;  4ETP A;  3L9H A;  2Y65 A;  1BG2 A;  1I5S A;  4GKR A;  4PK4 A;  4AS7 A;  2UYM A;  3DC4 A;  2X51 A;  1MMG A;  2X2R A;  3U06 A;  3NWN A;  5LT1 A;  3K5E A;  4B7B A;  2OWM A;  1F9W A;  1BR4 A;  1BR1 A;  2ZFI A;  3H4S A;  1YRS A;  2IEH A;  3BFN A;  1MMN A;  2PG2 A;  2XT3 A;  4PJJ A;  4HNA K;  1VFW A;  3B6U A;  3CJO A;  4LNU K;  3T0Q A;  4AP0 A;  1VFV A;  1X88 A;  4PFO A;  1F9U A;  1F9V A;  4ANJ A;  1D1B A;  2HEH A;  3ZCW A;  1SDM A;  2FME A;  2X7E A;  2X7D A;  2GM1 A;  2VB6 A;  1F9T A;  1T5C A;  2ZFM A;  3PXN A;  1I6I A;  1MMD A;  3DCB A;  1D0Y A;  4DBQ A;  3CNZ A;  2FL2 A;  2VVG A;  3KAR A;  1V8K A;  3WRD A;  2KIN A;  1MMA A;  1N6M A;  2FL6 A;  3GBJ A;  4PJL A;  3COB A;  2MYS A;  1V8J A;  1VFX A;  1CZ7 A;  1LVK A;  4A28 A;  1KK7 A;  1Q0B A;  1II6 A;  1MKJ A;  3ZFD A;  1FMV A;  4UBF A;  4Y05 A;  5HLE A;  3ZFC A;  2ZFK A;  5GSZ A;  2X7C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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