4A14 | Genus

Total Genus 101

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	101
sequence length	336
structure length	296
Chain Sequence	EEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEDEQGIVPRAMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTHLSSRSHTVFTVTLEQRGQLLVSKFHFVDLAGSERVQINSSLLALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQ

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Motor protein
source organism	Homo sapiens
publication title	Structural Insights Into Human Kif7, a Kinesin Involved in Hedgehog Signalling. pubmed doi rcsb
molecule keywords	KINESIN-LIKE PROTEIN KIF7
total genus	101
structure length	296
sequence length	336
ec nomenclature
pdb deposition date	2011-09-14

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.850.10	Alpha Beta	3-Layer(aba) Sandwich	Kinesin	Kinesin motor domain	4a14A00

4E7SA 1RY6A 3LREA 2VVGA 4ZHIA 5LT2A 3KINA 1D0ZA 1MNEA 2UYIA 2UYMA 3K5EA 1Q0BA 2OWMA 5LT1A 2G1QA 1V8JA 4BN2A 1VFXA 1BR4A 1F9TA 2MYSA 4ZCAA 1KK7A 1N6MA 2NCDA 4A51A 4A14A 2WOGA 1I5SA 1VOMA 4PJLA 2X2RA 2FL6A 2X7EA 4BXNA 2Q2YA 1MKJA 3WRDA 2X51A 4Y05A 5LT3A 4PJJA 4A5YA 4DBQA 3GBJA 1SDMA 1I6IA 3CJOA 4B7BA 2V26A 3B6VA 4LNUK 1VFVA 3COBA 1BR2A 4DBRA 2X7DA 3KARA 1D0XA 2KINA 4PFPA 1F9WA 1MMGA 1BR1A 1MMDA 1FMVA 5HLEA 5LT0A 4ETPA 1D1AA 2Q2ZA 2ZFMA 3DCBA 2HEHA 4AS7A 1D0YA 1MMAA 2GM1A 3KENA 2PG2A 2XAEA 3U06A 4BBGA 2FL2A 2GRYA 2FMEA 2Y5WA 3WPNA 3PXNA 1D1BA 3HQDA 1T5CA 1F9VA 1II6A 4FRZA 4UBFA 2X7CA 3ZCWA 3H4SA 4HNAK 4PFOA 1D1CA 3L9HA 4H1GA 3BFNA 5GSZA 1MMNA 1LVKA 1V8KA 2VASA 3NWNA 4PK4A 2VB6A 4A50A 3T0QA 2Y65A 1CZ7A 4E7ZA 1VFWA 5LT4A 1F9UA 2IEHA 4PJMA 1G8XA 1VFZA 4GKRA 4A1ZA 2ZFJA 3ZFCA 3ZFDA 3B6UA 4A28A 1GOJA 3DC4A 2ZFLA 3L1CA 1LKXA 3K3BA 1FMWA 2ZFIA 3X2TA 2ZFKA 3CNZA 4PJNA 4ANJA 4AP0A 1YRSA 2XT3A 1X88A 2FKYA 1BG2A
chains in the Genus database with same CATH superfamily

4E7SA 1RY6A 3LREA 2VVGA 4ZHIA 5LT2A 3KINA 1D0ZA 1MNEA 2UYIA 2UYMA 3K5EA 1Q0BA 2OWMA 5LT1A 2G1QA 1V8JA 4BN2A 1VFXA 1BR4A 1F9TA 2MYSA 4ZCAA 1KK7A 1N6MA 2NCDA 4ETPB 4A51A 4A14A 2WOGA 1I5SA 1VOMA 4PJLA 2X2RA 2FL6A 2X7EA 4BXNA 2Q2YA 1MKJA 3WRDA 2X51A 4Y05A 5LT3A 4PJJA 4A5YA 4DBQA 3GBJA 1SDMA 1I6IA 3CJOA 4B7BA 2V26A 3B6VA 2O0AA 4LNUK 1VFVA 3COBA 1BR2A 4DBRA 2X7DA 3KARA 1D0XA 2KINA 4PFPA 1F9WA 1MMGA 1BR1A 1MMDA 1FMVA 5HLEA 5LT0A 4ETPA 1D1AA 2Q2ZA 2ZFMA 3DCBA 2HEHA 4AS7A 1D0YA 1MMAA 2GM1A 3KENA 2PG2A 2XAEA 3U06A 4BBGA 2FL2A 2GRYA 2FMEA 2Y5WA 3WPNA 3PXNA 1D1BA 3HQDA 1T5CA 1F9VA 1II6A 4FRZA 4UBFA 2X7CA 3ZCWA 3H4SA 4HNAK 4PFOA 1D1CA 3L9HA 4GKPA 4H1GA 3BFNA 5GSZA 1MMNA 1LVKA 1V8KA 2VASA 3NWNA 4PK4A 2VB6A 4A50A 3T0QA 2Y65A 1CZ7A 4E7ZA 1VFWA 5LT4A 1F9UA 4GKQA 2IEHA 4PJMA 1G8XA 1VFZA 4GKRA 4A1ZA 2ZFJA 3ZFCA 3ZFDA 3B6UA 4A28A 1GOJA 3DC4A 2ZFLA 3L1CA 1LKXA 3K3BA 1FMWA 2ZFIA 3X2TA 2ZFKA 3CNZA 4PJNA 4ANJA 4AP0A 1YRSA 2XT3A 1X88A 2FKYA 1BG2A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4E7S A;  1RY6 A;  3LRE A;  2VVG A;  4ZHI A;  5LT2 A;  3KIN A;  1D0Z A;  1MNE A;  2UYI A;  2UYM A;  3K5E A;  1Q0B A;  2OWM A;  5LT1 A;  2G1Q A;  1V8J A;  4BN2 A;  1VFX A;  1BR4 A;  1F9T A;  2MYS A;  4ZCA A;  1KK7 A;  1N6M A;  2NCD A;  4A51 A;  4A14 A;  2WOG A;  1I5S A;  1VOM A;  4PJL A;  2X2R A;  2FL6 A;  2X7E A;  4BXN A;  2Q2Y A;  1MKJ A;  3WRD A;  2X51 A;  4Y05 A;  5LT3 A;  4PJJ A;  4A5Y A;  4DBQ A;  3GBJ A;  1SDM A;  1I6I A;  3CJO A;  4B7B A;  2V26 A;  3B6V A;  4LNU K;  1VFV A;  3COB A;  1BR2 A;  4DBR A;  2X7D A;  3KAR A;  1D0X A;  2KIN A;  4PFP A;  1F9W A;  1MMG A;  1BR1 A;  1MMD A;  1FMV A;  5HLE A;  5LT0 A;  4ETP A;  1D1A A;  2Q2Z A;  2ZFM A;  3DCB A;  2HEH A;  4AS7 A;  1D0Y A;  1MMA A;  2GM1 A;  3KEN A;  2PG2 A;  2XAE A;  3U06 A;  4BBG A;  2FL2 A;  2GRY A;  2FME A;  2Y5W A;  3WPN A;  3PXN A;  1D1B A;  3HQD A;  1T5C A;  1F9V A;  1II6 A;  4FRZ A;  4UBF A;  2X7C A;  3ZCW A;  3H4S A;  4HNA K;  4PFO A;  1D1C A;  3L9H A;  4H1G A;  3BFN A;  5GSZ A;  1MMN A;  1LVK A;  1V8K A;  2VAS A;  3NWN A;  4PK4 A;  2VB6 A;  4A50 A;  3T0Q A;  2Y65 A;  1CZ7 A;  4E7Z A;  1VFW A;  5LT4 A;  1F9U A;  2IEH A;  4PJM A;  1G8X A;  1VFZ A;  4GKR A;  4A1Z A;  2ZFJ A;  3ZFC A;  3ZFD A;  3B6U A;  4A28 A;  1GOJ A;  3DC4 A;  2ZFL A;  3L1C A;  1LKX A;  3K3B A;  1FMW A;  2ZFI A;  3X2T A;  2ZFK A;  3CNZ A;  4PJN A;  4ANJ A;  4AP0 A;  1YRS A;  2XT3 A;  1X88 A;  2FKY A;  1BG2 A; 
#chains in the Genus database with same CATH topology
 4E7S A;  1RY6 A;  3LRE A;  2VVG A;  4ZHI A;  5LT2 A;  3KIN A;  1D0Z A;  1MNE A;  2UYI A;  2UYM A;  3K5E A;  1Q0B A;  2OWM A;  5LT1 A;  2G1Q A;  1V8J A;  4BN2 A;  1VFX A;  1BR4 A;  1F9T A;  2MYS A;  4ZCA A;  1KK7 A;  1N6M A;  2NCD A;  4ETP B;  4A51 A;  4A14 A;  2WOG A;  1I5S A;  1VOM A;  4PJL A;  2X2R A;  2FL6 A;  2X7E A;  4BXN A;  2Q2Y A;  1MKJ A;  3WRD A;  2X51 A;  4Y05 A;  5LT3 A;  4PJJ A;  4A5Y A;  4DBQ A;  3GBJ A;  1SDM A;  1I6I A;  3CJO A;  4B7B A;  2V26 A;  3B6V A;  2O0A A;  4LNU K;  1VFV A;  3COB A;  1BR2 A;  4DBR A;  2X7D A;  3KAR A;  1D0X A;  2KIN A;  4PFP A;  1F9W A;  1MMG A;  1BR1 A;  1MMD A;  1FMV A;  5HLE A;  5LT0 A;  4ETP A;  1D1A A;  2Q2Z A;  2ZFM A;  3DCB A;  2HEH A;  4AS7 A;  1D0Y A;  1MMA A;  2GM1 A;  3KEN A;  2PG2 A;  2XAE A;  3U06 A;  4BBG A;  2FL2 A;  2GRY A;  2FME A;  2Y5W A;  3WPN A;  3PXN A;  1D1B A;  3HQD A;  1T5C A;  1F9V A;  1II6 A;  4FRZ A;  4UBF A;  2X7C A;  3ZCW A;  3H4S A;  4HNA K;  4PFO A;  1D1C A;  3L9H A;  4GKP A;  4H1G A;  3BFN A;  5GSZ A;  1MMN A;  1LVK A;  1V8K A;  2VAS A;  3NWN A;  4PK4 A;  2VB6 A;  4A50 A;  3T0Q A;  2Y65 A;  1CZ7 A;  4E7Z A;  1VFW A;  5LT4 A;  1F9U A;  4GKQ A;  2IEH A;  4PJM A;  1G8X A;  1VFZ A;  4GKR A;  4A1Z A;  2ZFJ A;  3ZFC A;  3ZFD A;  3B6U A;  4A28 A;  1GOJ A;  3DC4 A;  2ZFL A;  3L1C A;  1LKX A;  3K3B A;  1FMW A;  2ZFI A;  3X2T A;  2ZFK A;  3CNZ A;  4PJN A;  4ANJ A;  4AP0 A;  1YRS A;  2XT3 A;  1X88 A;  2FKY A;  1BG2 A; 
#chains in the Genus database with same CATH homology
 4E7S A;  1RY6 A;  3LRE A;  2VVG A;  4ZHI A;  5LT2 A;  3KIN A;  1D0Z A;  1MNE A;  2UYI A;  2UYM A;  3K5E A;  1Q0B A;  2OWM A;  5LT1 A;  2G1Q A;  1V8J A;  4BN2 A;  1VFX A;  1BR4 A;  1F9T A;  2MYS A;  4ZCA A;  1KK7 A;  1N6M A;  2NCD A;  4A51 A;  4A14 A;  2WOG A;  1I5S A;  1VOM A;  4PJL A;  2X2R A;  2FL6 A;  2X7E A;  4BXN A;  2Q2Y A;  1MKJ A;  3WRD A;  2X51 A;  4Y05 A;  5LT3 A;  4PJJ A;  4A5Y A;  4DBQ A;  3GBJ A;  1SDM A;  1I6I A;  3CJO A;  4B7B A;  2V26 A;  3B6V A;  4LNU K;  1VFV A;  3COB A;  1BR2 A;  4DBR A;  2X7D A;  3KAR A;  1D0X A;  2KIN A;  4PFP A;  1F9W A;  1MMG A;  1BR1 A;  1MMD A;  1FMV A;  5HLE A;  5LT0 A;  4ETP A;  1D1A A;  2Q2Z A;  2ZFM A;  3DCB A;  2HEH A;  4AS7 A;  1D0Y A;  1MMA A;  2GM1 A;  3KEN A;  2PG2 A;  2XAE A;  3U06 A;  4BBG A;  2FL2 A;  2GRY A;  2FME A;  2Y5W A;  3WPN A;  3PXN A;  1D1B A;  3HQD A;  1T5C A;  1F9V A;  1II6 A;  4FRZ A;  4UBF A;  2X7C A;  3ZCW A;  3H4S A;  4HNA K;  4PFO A;  1D1C A;  3L9H A;  4H1G A;  3BFN A;  5GSZ A;  1MMN A;  1LVK A;  1V8K A;  2VAS A;  3NWN A;  4PK4 A;  2VB6 A;  4A50 A;  3T0Q A;  2Y65 A;  1CZ7 A;  4E7Z A;  1VFW A;  5LT4 A;  1F9U A;  2IEH A;  4PJM A;  1G8X A;  1VFZ A;  4GKR A;  4A1Z A;  2ZFJ A;  3ZFC A;  3ZFD A;  3B6U A;  4A28 A;  1GOJ A;  3DC4 A;  2ZFL A;  3L1C A;  1LKX A;  3K3B A;  1FMW A;  2ZFI A;  3X2T A;  2ZFK A;  3CNZ A;  4PJN A;  4ANJ A;  4AP0 A;  1YRS A;  2XT3 A;  1X88 A;  2FKY A;  1BG2 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4A14A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN