4A14A

Human kif7, a kinesin involved in hedgehog signalling
Total Genus 101
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
336
structure length
296
Chain Sequence
EEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEDEQGIVPRAMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTHLSSRSHTVFTVTLEQRGQLLVSKFHFVDLAGSERVQINSSLLALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural Insights Into Human Kif7, a Kinesin Involved in Hedgehog Signalling.
pubmed doi rcsb
molecule tags Motor protein
source organism Homo sapiens
molecule keywords KINESIN-LIKE PROTEIN KIF7
total genus 101
structure length 296
sequence length 336
ec nomenclature
pdb deposition date 2011-09-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 4a14A00
4E7SA 2VVGA 3ZFCA 4A1ZA 2ZFMA 4UBFA 3H4SA 1MMDA 4LNUK 3L9HA 2FL6A 2X2RA 2OWMA 1I6IA 2UYMA 4PFPA 3HQDA 2IEHA 1X88A 1YRSA 4A5YA 4PK4A 1D1CA 3CJOA 1D1AA 3WPNA 2VB6A 3B6VA 1MMGA 1G8XA 1Q0BA 4ZHIA 3DCBA 2X7CA 1BR2A 4BBGA 5LT2A 4ANJA 3L1CA 3T0QA 1BG2A 3PXNA 4A50A 1VFXA 2G1QA 3ZCWA 2Q2ZA 1T5CA 2XAEA 1D0ZA 2ZFLA 2ZFJA 1F9TA 3WRDA 4BN2A 4ETPA 5LT0A 2X7DA 2VASA 3LREA 1LVKA 2HEHA 1D0XA 3KARA 1LKXA 3X2TA 1SDMA 4ZCAA 1II6A 2XT3A 4A28A 2V26A 1MNEA 1VFWA 1V8JA 4HNAK 1FMWA 5GSZA 4AP0A 5LT4A 3K3BA 1BR1A 2ZFIA 1N6MA 1F9UA 1VFZA 2UYIA 2KINA 4E7ZA 1BR4A 3CNZA 2FMEA 1D0YA 4GKRA 2GRYA 4A51A 3U06A 2WOGA 3ZFDA 5LT3A 1V8KA 3BFNA 1MKJA 3DC4A 4DBRA 1D1BA 4PJLA 5HLEA 3KENA 3GBJA 4AS7A 3NWNA 5LT1A 4A14A 1I5SA 2FKYA 2NCDA 1KK7A 1F9WA 1RY6A 1FMVA 2GM1A 2FL2A 2MYSA 2PG2A 1MMAA 4H1GA 2ZFKA 3B6UA 2Q2YA 4FRZA 4PJMA 1F9VA 2X7EA 1VOMA 1VFVA 2X51A 4BXNA 4Y05A 2Y5WA 3K5EA 4PFOA 1MMNA 3KINA 4DBQA 4PJNA 2Y65A 1CZ7A 3COBA 4PJJA 1GOJA 4B7BA
chains in the Genus database with same CATH superfamily
4E7SA 2VVGA 3ZFCA 4A1ZA 2ZFMA 4UBFA 3H4SA 1MMDA 4LNUK 3L9HA 2FL6A 2X2RA 2OWMA 1I6IA 2UYMA 4PFPA 3HQDA 2IEHA 1X88A 1YRSA 4A5YA 4PK4A 1D1CA 3CJOA 1D1AA 3WPNA 2VB6A 3B6VA 1MMGA 1G8XA 1Q0BA 4ZHIA 3DCBA 2X7CA 1BR2A 4BBGA 5LT2A 4ANJA 3L1CA 2O0AA 3T0QA 1BG2A 3PXNA 4A50A 1VFXA 2G1QA 3ZCWA 2Q2ZA 1T5CA 2XAEA 4GKQA 1D0ZA 2ZFLA 2ZFJA 1F9TA 3WRDA 4BN2A 4ETPA 5LT0A 2X7DA 2VASA 3LREA 1LVKA 2HEHA 1D0XA 3KARA 1LKXA 3X2TA 1SDMA 4ZCAA 1II6A 2XT3A 4A28A 2V26A 1MNEA 1VFWA 1V8JA 4HNAK 1FMWA 5GSZA 4AP0A 5LT4A 3K3BA 1BR1A 2ZFIA 1N6MA 1F9UA 1VFZA 2UYIA 2KINA 4E7ZA 1BR4A 3CNZA 2FMEA 1D0YA 4GKRA 2GRYA 4ETPB 4A51A 3U06A 2WOGA 3ZFDA 5LT3A 1V8KA 3BFNA 1MKJA 3DC4A 4DBRA 1D1BA 4PJLA 5HLEA 3KENA 3GBJA 4AS7A 3NWNA 5LT1A 4A14A 1I5SA 2FKYA 2NCDA 1KK7A 1F9WA 1RY6A 1FMVA 2GM1A 2FL2A 2MYSA 2PG2A 1MMAA 4H1GA 2ZFKA 3B6UA 2Q2YA 4FRZA 4PJMA 1F9VA 2X7EA 4GKPA 1VOMA 1VFVA 2X51A 4BXNA 4Y05A 2Y5WA 3K5EA 4PFOA 1MMNA 3KINA 4DBQA 4PJNA 2Y65A 1CZ7A 3COBA 4PJJA 1GOJA 4B7BA
chains in the Genus database with same CATH topology
4E7SA 2VVGA 3ZFCA 4A1ZA 2ZFMA 4UBFA 3H4SA 1MMDA 4LNUK 3L9HA 2FL6A 2X2RA 2OWMA 1I6IA 2UYMA 4PFPA 3HQDA 2IEHA 1X88A 1YRSA 4A5YA 4PK4A 1D1CA 3CJOA 1D1AA 3WPNA 2VB6A 3B6VA 1MMGA 1G8XA 1Q0BA 4ZHIA 3DCBA 2X7CA 1BR2A 4BBGA 5LT2A 4ANJA 3L1CA 3T0QA 1BG2A 3PXNA 4A50A 1VFXA 2G1QA 3ZCWA 2Q2ZA 1T5CA 2XAEA 1D0ZA 2ZFLA 2ZFJA 1F9TA 3WRDA 4BN2A 4ETPA 5LT0A 2X7DA 2VASA 3LREA 1LVKA 2HEHA 1D0XA 3KARA 1LKXA 3X2TA 1SDMA 4ZCAA 1II6A 2XT3A 4A28A 2V26A 1MNEA 1VFWA 1V8JA 4HNAK 1FMWA 5GSZA 4AP0A 5LT4A 3K3BA 1BR1A 2ZFIA 1N6MA 1F9UA 1VFZA 2UYIA 2KINA 4E7ZA 1BR4A 3CNZA 2FMEA 1D0YA 4GKRA 2GRYA 4A51A 3U06A 2WOGA 3ZFDA 5LT3A 1V8KA 3BFNA 1MKJA 3DC4A 4DBRA 1D1BA 4PJLA 5HLEA 3KENA 3GBJA 4AS7A 3NWNA 5LT1A 4A14A 1I5SA 2FKYA 2NCDA 1KK7A 1F9WA 1RY6A 1FMVA 2GM1A 2FL2A 2MYSA 2PG2A 1MMAA 4H1GA 2ZFKA 3B6UA 2Q2YA 4FRZA 4PJMA 1F9VA 2X7EA 1VOMA 1VFVA 2X51A 4BXNA 4Y05A 2Y5WA 3K5EA 4PFOA 1MMNA 3KINA 4DBQA 4PJNA 2Y65A 1CZ7A 3COBA 4PJJA 1GOJA 4B7BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E7S A;  2VVG A;  3ZFC A;  4A1Z A;  2ZFM A;  4UBF A;  3H4S A;  1MMD A;  4LNU K;  3L9H A;  2FL6 A;  2X2R A;  2OWM A;  1I6I A;  2UYM A;  4PFP A;  3HQD A;  2IEH A;  1X88 A;  1YRS A;  4A5Y A;  4PK4 A;  1D1C A;  3CJO A;  1D1A A;  3WPN A;  2VB6 A;  3B6V A;  1MMG A;  1G8X A;  1Q0B A;  4ZHI A;  3DCB A;  2X7C A;  1BR2 A;  4BBG A;  5LT2 A;  4ANJ A;  3L1C A;  3T0Q A;  1BG2 A;  3PXN A;  4A50 A;  1VFX A;  2G1Q A;  3ZCW A;  2Q2Z A;  1T5C A;  2XAE A;  1D0Z A;  2ZFL A;  2ZFJ A;  1F9T A;  3WRD A;  4BN2 A;  4ETP A;  5LT0 A;  2X7D A;  2VAS A;  3LRE A;  1LVK A;  2HEH A;  1D0X A;  3KAR A;  1LKX A;  3X2T A;  1SDM A;  4ZCA A;  1II6 A;  2XT3 A;  4A28 A;  2V26 A;  1MNE A;  1VFW A;  1V8J A;  4HNA K;  1FMW A;  5GSZ A;  4AP0 A;  5LT4 A;  3K3B A;  1BR1 A;  2ZFI A;  1N6M A;  1F9U A;  1VFZ A;  2UYI A;  2KIN A;  4E7Z A;  1BR4 A;  3CNZ A;  2FME A;  1D0Y A;  4GKR A;  2GRY A;  4A51 A;  3U06 A;  2WOG A;  3ZFD A;  5LT3 A;  1V8K A;  3BFN A;  1MKJ A;  3DC4 A;  4DBR A;  1D1B A;  4PJL A;  5HLE A;  3KEN A;  3GBJ A;  4AS7 A;  3NWN A;  5LT1 A;  4A14 A;  1I5S A;  2FKY A;  2NCD A;  1KK7 A;  1F9W A;  1RY6 A;  1FMV A;  2GM1 A;  2FL2 A;  2MYS A;  2PG2 A;  1MMA A;  4H1G A;  2ZFK A;  3B6U A;  2Q2Y A;  4FRZ A;  4PJM A;  1F9V A;  2X7E A;  1VOM A;  1VFV A;  2X51 A;  4BXN A;  4Y05 A;  2Y5W A;  3K5E A;  4PFO A;  1MMN A;  3KIN A;  4DBQ A;  4PJN A;  2Y65 A;  1CZ7 A;  3COB A;  4PJJ A;  1GOJ A;  4B7B A; 
#chains in the Genus database with same CATH topology
 4E7S A;  2VVG A;  3ZFC A;  4A1Z A;  2ZFM A;  4UBF A;  3H4S A;  1MMD A;  4LNU K;  3L9H A;  2FL6 A;  2X2R A;  2OWM A;  1I6I A;  2UYM A;  4PFP A;  3HQD A;  2IEH A;  1X88 A;  1YRS A;  4A5Y A;  4PK4 A;  1D1C A;  3CJO A;  1D1A A;  3WPN A;  2VB6 A;  3B6V A;  1MMG A;  1G8X A;  1Q0B A;  4ZHI A;  3DCB A;  2X7C A;  1BR2 A;  4BBG A;  5LT2 A;  4ANJ A;  3L1C A;  2O0A A;  3T0Q A;  1BG2 A;  3PXN A;  4A50 A;  1VFX A;  2G1Q A;  3ZCW A;  2Q2Z A;  1T5C A;  2XAE A;  4GKQ A;  1D0Z A;  2ZFL A;  2ZFJ A;  1F9T A;  3WRD A;  4BN2 A;  4ETP A;  5LT0 A;  2X7D A;  2VAS A;  3LRE A;  1LVK A;  2HEH A;  1D0X A;  3KAR A;  1LKX A;  3X2T A;  1SDM A;  4ZCA A;  1II6 A;  2XT3 A;  4A28 A;  2V26 A;  1MNE A;  1VFW A;  1V8J A;  4HNA K;  1FMW A;  5GSZ A;  4AP0 A;  5LT4 A;  3K3B A;  1BR1 A;  2ZFI A;  1N6M A;  1F9U A;  1VFZ A;  2UYI A;  2KIN A;  4E7Z A;  1BR4 A;  3CNZ A;  2FME A;  1D0Y A;  4GKR A;  2GRY A;  4ETP B;  4A51 A;  3U06 A;  2WOG A;  3ZFD A;  5LT3 A;  1V8K A;  3BFN A;  1MKJ A;  3DC4 A;  4DBR A;  1D1B A;  4PJL A;  5HLE A;  3KEN A;  3GBJ A;  4AS7 A;  3NWN A;  5LT1 A;  4A14 A;  1I5S A;  2FKY A;  2NCD A;  1KK7 A;  1F9W A;  1RY6 A;  1FMV A;  2GM1 A;  2FL2 A;  2MYS A;  2PG2 A;  1MMA A;  4H1G A;  2ZFK A;  3B6U A;  2Q2Y A;  4FRZ A;  4PJM A;  1F9V A;  2X7E A;  4GKP A;  1VOM A;  1VFV A;  2X51 A;  4BXN A;  4Y05 A;  2Y5W A;  3K5E A;  4PFO A;  1MMN A;  3KIN A;  4DBQ A;  4PJN A;  2Y65 A;  1CZ7 A;  3COB A;  4PJJ A;  1GOJ A;  4B7B A; 
#chains in the Genus database with same CATH homology
 4E7S A;  2VVG A;  3ZFC A;  4A1Z A;  2ZFM A;  4UBF A;  3H4S A;  1MMD A;  4LNU K;  3L9H A;  2FL6 A;  2X2R A;  2OWM A;  1I6I A;  2UYM A;  4PFP A;  3HQD A;  2IEH A;  1X88 A;  1YRS A;  4A5Y A;  4PK4 A;  1D1C A;  3CJO A;  1D1A A;  3WPN A;  2VB6 A;  3B6V A;  1MMG A;  1G8X A;  1Q0B A;  4ZHI A;  3DCB A;  2X7C A;  1BR2 A;  4BBG A;  5LT2 A;  4ANJ A;  3L1C A;  3T0Q A;  1BG2 A;  3PXN A;  4A50 A;  1VFX A;  2G1Q A;  3ZCW A;  2Q2Z A;  1T5C A;  2XAE A;  1D0Z A;  2ZFL A;  2ZFJ A;  1F9T A;  3WRD A;  4BN2 A;  4ETP A;  5LT0 A;  2X7D A;  2VAS A;  3LRE A;  1LVK A;  2HEH A;  1D0X A;  3KAR A;  1LKX A;  3X2T A;  1SDM A;  4ZCA A;  1II6 A;  2XT3 A;  4A28 A;  2V26 A;  1MNE A;  1VFW A;  1V8J A;  4HNA K;  1FMW A;  5GSZ A;  4AP0 A;  5LT4 A;  3K3B A;  1BR1 A;  2ZFI A;  1N6M A;  1F9U A;  1VFZ A;  2UYI A;  2KIN A;  4E7Z A;  1BR4 A;  3CNZ A;  2FME A;  1D0Y A;  4GKR A;  2GRY A;  4A51 A;  3U06 A;  2WOG A;  3ZFD A;  5LT3 A;  1V8K A;  3BFN A;  1MKJ A;  3DC4 A;  4DBR A;  1D1B A;  4PJL A;  5HLE A;  3KEN A;  3GBJ A;  4AS7 A;  3NWN A;  5LT1 A;  4A14 A;  1I5S A;  2FKY A;  2NCD A;  1KK7 A;  1F9W A;  1RY6 A;  1FMV A;  2GM1 A;  2FL2 A;  2MYS A;  2PG2 A;  1MMA A;  4H1G A;  2ZFK A;  3B6U A;  2Q2Y A;  4FRZ A;  4PJM A;  1F9V A;  2X7E A;  1VOM A;  1VFV A;  2X51 A;  4BXN A;  4Y05 A;  2Y5W A;  3K5E A;  4PFO A;  1MMN A;  3KIN A;  4DBQ A;  4PJN A;  2Y65 A;  1CZ7 A;  3COB A;  4PJJ A;  1GOJ A;  4B7B A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...