4AP0 | Genus

Total Genus 92

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	92
sequence length	350
structure length	325
Chain Sequence	KNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKEVKIGKLNLVDLAGSENIGRINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVN

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Motor protein
source organism	Homo sapiens
publication title	The Structure of the Ternary Eg5-Adp-Ispinesib Complex pubmed doi rcsb
molecule keywords	KINESIN-LIKE PROTEIN KIF11
total genus	92
structure length	325
sequence length	350
chains with identical sequence	B, C, D
ec nomenclature
pdb deposition date	2012-03-30

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00225	Kinesin	Kinesin motor domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.850.10	Alpha Beta	3-Layer(aba) Sandwich	Kinesin	Kinesin motor domain	4ap0A00

1VFWA 4FRZA 2GRYA 1D1AA 4E7SA 1MMNA 3CNZA 2PG2A 1BR4A 2MYSA 1I6IA 1N6MA 3LREA 3PXNA 1LKXA 2ZFIA 4ANJA 3CJOA 3U06A 1F9UA 1MKJA 3K5EA 4PJJA 2KINA 1YRSA 3DCBA 3B6VA 2VASA 5LT4A 1V8JA 4PJLA 3KARA 1D1BA 2VB6A 2FL2A 1F9WA 2Y5WA 1BG2A 2X7DA 5LT0A 4AP0A 1D0ZA 1LVKA 2XT3A 2X7CA 3T0QA 5HLEA 4A28A 1CZ7A 5LT2A 2UYMA 4E7ZA 3X2TA 2V26A 3HQDA 2NCDA 2VVGA 1MMDA 4PK4A 1MMGA 1II6A 2ZFJA 2WOGA 3L1CA 4BXNA 4AS7A 3ZCWA 4PFPA 3H4SA 2OWMA 3ZFCA 2XAEA 2Q2ZA 4ETPA 3DC4A 2ZFMA 4B7BA 4Y05A 5GSZA 1FMWA 4GKRA 4BBGA 1F9TA 1VFVA 2Q2YA 1D0YA 2FL6A 4H1GA 4A5YA 2ZFLA 4A14A 1BR1A 1MNEA 3BFNA 2UYIA 1T5CA 1MMAA 2GM1A 2ZFKA 1G8XA 4PJMA 4HNAK 5LT3A 1VFXA 2FKYA 1X88A 4BN2A 4DBRA 1V8KA 3NWNA 3WPNA 4PJNA 4ZCAA 3ZFDA 1I5SA 1D0XA 2HEHA 4PFOA 3B6UA 3GBJA 1F9VA 4UBFA 2X51A 2X7EA 1VOMA 4A51A 1BR2A 4ZHIA 1D1CA 2Y65A 4DBQA 4A50A 1SDMA 1KK7A 2G1QA 3WRDA 1Q0BA 3L9HA 1FMVA 2FMEA 3KINA 5LT1A 2X2RA 1GOJA 2IEHA 1RY6A 3K3BA 3KENA 4A1ZA 3COBA 4LNUK 1VFZA
chains in the Genus database with same CATH superfamily

1VFWA 4FRZA 2GRYA 1D1AA 4E7SA 1MMNA 3CNZA 2PG2A 1BR4A 2MYSA 1I6IA 1N6MA 3LREA 3PXNA 1LKXA 2ZFIA 4ANJA 3CJOA 3U06A 1F9UA 1MKJA 3K5EA 4PJJA 2KINA 1YRSA 3DCBA 3B6VA 2VASA 5LT4A 1V8JA 4PJLA 3KARA 1D1BA 4ETPB 2VB6A 2FL2A 1F9WA 2Y5WA 1BG2A 2X7DA 5LT0A 4AP0A 1D0ZA 1LVKA 2XT3A 2X7CA 3T0QA 5HLEA 4A28A 1CZ7A 5LT2A 2UYMA 4E7ZA 3X2TA 2V26A 3HQDA 2NCDA 2VVGA 1MMDA 4PK4A 1MMGA 1II6A 2ZFJA 2WOGA 3L1CA 4BXNA 4AS7A 3ZCWA 4PFPA 3H4SA 2OWMA 4GKQA 3ZFCA 2XAEA 2Q2ZA 4ETPA 3DC4A 2ZFMA 4B7BA 4Y05A 5GSZA 1FMWA 4GKRA 4BBGA 1F9TA 1VFVA 2Q2YA 1D0YA 2FL6A 4H1GA 4A5YA 2ZFLA 4A14A 1BR1A 1MNEA 3BFNA 2UYIA 1T5CA 1MMAA 2GM1A 2ZFKA 1G8XA 4PJMA 4HNAK 5LT3A 1VFXA 2FKYA 1X88A 4BN2A 4DBRA 1V8KA 3NWNA 3WPNA 4PJNA 4ZCAA 4GKPA 3ZFDA 1I5SA 1D0XA 2HEHA 4PFOA 3B6UA 3GBJA 1F9VA 4UBFA 2X51A 2X7EA 1VOMA 4A51A 1BR2A 4ZHIA 2O0AA 1D1CA 2Y65A 4DBQA 4A50A 1SDMA 1KK7A 2G1QA 3WRDA 1Q0BA 3L9HA 1FMVA 2FMEA 3KINA 5LT1A 2X2RA 1GOJA 2IEHA 1RY6A 3K3BA 3KENA 4A1ZA 3COBA 4LNUK 1VFZA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1VFW A;  4FRZ A;  2GRY A;  1D1A A;  4E7S A;  1MMN A;  3CNZ A;  2PG2 A;  1BR4 A;  2MYS A;  1I6I A;  1N6M A;  3LRE A;  3PXN A;  1LKX A;  2ZFI A;  4ANJ A;  3CJO A;  3U06 A;  1F9U A;  1MKJ A;  3K5E A;  4PJJ A;  2KIN A;  1YRS A;  3DCB A;  3B6V A;  2VAS A;  5LT4 A;  1V8J A;  4PJL A;  3KAR A;  1D1B A;  2VB6 A;  2FL2 A;  1F9W A;  2Y5W A;  1BG2 A;  2X7D A;  5LT0 A;  4AP0 A;  1D0Z A;  1LVK A;  2XT3 A;  2X7C A;  3T0Q A;  5HLE A;  4A28 A;  1CZ7 A;  5LT2 A;  2UYM A;  4E7Z A;  3X2T A;  2V26 A;  3HQD A;  2NCD A;  2VVG A;  1MMD A;  4PK4 A;  1MMG A;  1II6 A;  2ZFJ A;  2WOG A;  3L1C A;  4BXN A;  4AS7 A;  3ZCW A;  4PFP A;  3H4S A;  2OWM A;  3ZFC A;  2XAE A;  2Q2Z A;  4ETP A;  3DC4 A;  2ZFM A;  4B7B A;  4Y05 A;  5GSZ A;  1FMW A;  4GKR A;  4BBG A;  1F9T A;  1VFV A;  2Q2Y A;  1D0Y A;  2FL6 A;  4H1G A;  4A5Y A;  2ZFL A;  4A14 A;  1BR1 A;  1MNE A;  3BFN A;  2UYI A;  1T5C A;  1MMA A;  2GM1 A;  2ZFK A;  1G8X A;  4PJM A;  4HNA K;  5LT3 A;  1VFX A;  2FKY A;  1X88 A;  4BN2 A;  4DBR A;  1V8K A;  3NWN A;  3WPN A;  4PJN A;  4ZCA A;  3ZFD A;  1I5S A;  1D0X A;  2HEH A;  4PFO A;  3B6U A;  3GBJ A;  1F9V A;  4UBF A;  2X51 A;  2X7E A;  1VOM A;  4A51 A;  1BR2 A;  4ZHI A;  1D1C A;  2Y65 A;  4DBQ A;  4A50 A;  1SDM A;  1KK7 A;  2G1Q A;  3WRD A;  1Q0B A;  3L9H A;  1FMV A;  2FME A;  3KIN A;  5LT1 A;  2X2R A;  1GOJ A;  2IEH A;  1RY6 A;  3K3B A;  3KEN A;  4A1Z A;  3COB A;  4LNU K;  1VFZ A; 
#chains in the Genus database with same CATH topology
 1VFW A;  4FRZ A;  2GRY A;  1D1A A;  4E7S A;  1MMN A;  3CNZ A;  2PG2 A;  1BR4 A;  2MYS A;  1I6I A;  1N6M A;  3LRE A;  3PXN A;  1LKX A;  2ZFI A;  4ANJ A;  3CJO A;  3U06 A;  1F9U A;  1MKJ A;  3K5E A;  4PJJ A;  2KIN A;  1YRS A;  3DCB A;  3B6V A;  2VAS A;  5LT4 A;  1V8J A;  4PJL A;  3KAR A;  1D1B A;  4ETP B;  2VB6 A;  2FL2 A;  1F9W A;  2Y5W A;  1BG2 A;  2X7D A;  5LT0 A;  4AP0 A;  1D0Z A;  1LVK A;  2XT3 A;  2X7C A;  3T0Q A;  5HLE A;  4A28 A;  1CZ7 A;  5LT2 A;  2UYM A;  4E7Z A;  3X2T A;  2V26 A;  3HQD A;  2NCD A;  2VVG A;  1MMD A;  4PK4 A;  1MMG A;  1II6 A;  2ZFJ A;  2WOG A;  3L1C A;  4BXN A;  4AS7 A;  3ZCW A;  4PFP A;  3H4S A;  2OWM A;  4GKQ A;  3ZFC A;  2XAE A;  2Q2Z A;  4ETP A;  3DC4 A;  2ZFM A;  4B7B A;  4Y05 A;  5GSZ A;  1FMW A;  4GKR A;  4BBG A;  1F9T A;  1VFV A;  2Q2Y A;  1D0Y A;  2FL6 A;  4H1G A;  4A5Y A;  2ZFL A;  4A14 A;  1BR1 A;  1MNE A;  3BFN A;  2UYI A;  1T5C A;  1MMA A;  2GM1 A;  2ZFK A;  1G8X A;  4PJM A;  4HNA K;  5LT3 A;  1VFX A;  2FKY A;  1X88 A;  4BN2 A;  4DBR A;  1V8K A;  3NWN A;  3WPN A;  4PJN A;  4ZCA A;  4GKP A;  3ZFD A;  1I5S A;  1D0X A;  2HEH A;  4PFO A;  3B6U A;  3GBJ A;  1F9V A;  4UBF A;  2X51 A;  2X7E A;  1VOM A;  4A51 A;  1BR2 A;  4ZHI A;  2O0A A;  1D1C A;  2Y65 A;  4DBQ A;  4A50 A;  1SDM A;  1KK7 A;  2G1Q A;  3WRD A;  1Q0B A;  3L9H A;  1FMV A;  2FME A;  3KIN A;  5LT1 A;  2X2R A;  1GOJ A;  2IEH A;  1RY6 A;  3K3B A;  3KEN A;  4A1Z A;  3COB A;  4LNU K;  1VFZ A; 
#chains in the Genus database with same CATH homology
 1VFW A;  4FRZ A;  2GRY A;  1D1A A;  4E7S A;  1MMN A;  3CNZ A;  2PG2 A;  1BR4 A;  2MYS A;  1I6I A;  1N6M A;  3LRE A;  3PXN A;  1LKX A;  2ZFI A;  4ANJ A;  3CJO A;  3U06 A;  1F9U A;  1MKJ A;  3K5E A;  4PJJ A;  2KIN A;  1YRS A;  3DCB A;  3B6V A;  2VAS A;  5LT4 A;  1V8J A;  4PJL A;  3KAR A;  1D1B A;  2VB6 A;  2FL2 A;  1F9W A;  2Y5W A;  1BG2 A;  2X7D A;  5LT0 A;  4AP0 A;  1D0Z A;  1LVK A;  2XT3 A;  2X7C A;  3T0Q A;  5HLE A;  4A28 A;  1CZ7 A;  5LT2 A;  2UYM A;  4E7Z A;  3X2T A;  2V26 A;  3HQD A;  2NCD A;  2VVG A;  1MMD A;  4PK4 A;  1MMG A;  1II6 A;  2ZFJ A;  2WOG A;  3L1C A;  4BXN A;  4AS7 A;  3ZCW A;  4PFP A;  3H4S A;  2OWM A;  3ZFC A;  2XAE A;  2Q2Z A;  4ETP A;  3DC4 A;  2ZFM A;  4B7B A;  4Y05 A;  5GSZ A;  1FMW A;  4GKR A;  4BBG A;  1F9T A;  1VFV A;  2Q2Y A;  1D0Y A;  2FL6 A;  4H1G A;  4A5Y A;  2ZFL A;  4A14 A;  1BR1 A;  1MNE A;  3BFN A;  2UYI A;  1T5C A;  1MMA A;  2GM1 A;  2ZFK A;  1G8X A;  4PJM A;  4HNA K;  5LT3 A;  1VFX A;  2FKY A;  1X88 A;  4BN2 A;  4DBR A;  1V8K A;  3NWN A;  3WPN A;  4PJN A;  4ZCA A;  3ZFD A;  1I5S A;  1D0X A;  2HEH A;  4PFO A;  3B6U A;  3GBJ A;  1F9V A;  4UBF A;  2X51 A;  2X7E A;  1VOM A;  4A51 A;  1BR2 A;  4ZHI A;  1D1C A;  2Y65 A;  4DBQ A;  4A50 A;  1SDM A;  1KK7 A;  2G1Q A;  3WRD A;  1Q0B A;  3L9H A;  1FMV A;  2FME A;  3KIN A;  5LT1 A;  2X2R A;  1GOJ A;  2IEH A;  1RY6 A;  3K3B A;  3KEN A;  4A1Z A;  3COB A;  4LNU K;  1VFZ A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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4AP0A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations