4LNUK

Nucleotide-free kinesin motor domain in complex with tubulin and a darpin
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
316
structure length
309
Chain Sequence
NIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDAAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGATERFVSSPDEVMDTIDEGKSNRHVASSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNARTTIVICCSPSSYNESETKSTLLFGQRAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movement
pubmed doi rcsb
molecule tags Cell cycle/motor protein
source organism Artificial gene
molecule keywords Tubulin alpha chain
total genus 96
structure length 309
sequence length 316
ec nomenclature
pdb deposition date 2013-07-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
K PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 4lnuK00
1F9TA 1MMAA 3K5EA 5LT2A 2X7CA 2X7EA 2G1QA 4FRZA 3WPNA 1RY6A 4PFOA 4PJNA 2FKYA 1G8XA 4ANJA 1BR4A 1SDMA 2PG2A 4E7ZA 3HQDA 4E7SA 1VFVA 3KINA 2FMEA 4A5YA 1CZ7A 3CJOA 2V26A 4ZHIA 4PJJA 4AP0A 2MYSA 2VASA 2WOGA 5LT4A 5LT1A 1I5SA 2XAEA 3L9HA 1KK7A 5GSZA 3H4SA 1VFWA 5LT0A 5LT3A 3L1CA 4BN2A 2Q2YA 1VFXA 3LREA 4BXNA 3PXNA 2X7DA 1GOJA 1MNEA 2X51A 2ZFIA 1FMVA 4A14A 4LNUK 2OWMA 2GRYA 3WRDA 3GBJA 2FL2A 3CNZA 2ZFKA 1D1BA 1VOMA 3B6UA 1II6A 5HLEA 2Q2ZA 4B7BA 1F9VA 1N6MA 1D0XA 1F9UA 1MMNA 3U06A 2IEHA 1LKXA 4PK4A 1YRSA 4HNAK 4Y05A 1Q0BA 3B6VA 3KARA 4ZCAA 3K3BA 1LVKA 4PFPA 2VVGA 1MKJA 2ZFMA 3T0QA 4DBRA 1D1CA 1F9WA 1MMGA 4GKRA 2X2RA 2FL6A 2NCDA 2ZFLA 2UYMA 1D0YA 3DCBA 4A28A 1V8JA 3ZCWA 4H1GA 4BBGA 2Y5WA 3NWNA 2KINA 4PJMA 3ZFCA 1MMDA 1BR2A 2UYIA 1D0ZA 2VB6A 2XT3A 4A50A 3ZFDA 2HEHA 4DBQA 1BG2A 4ETPA 2GM1A 3COBA 1X88A 4PJLA 2ZFJA 4UBFA 2Y65A 4A1ZA 4A51A 1T5CA 1VFZA 3BFNA 1D1AA 1BR1A 3X2TA 3DC4A 4AS7A 1FMWA 1I6IA 3KENA 1V8KA
chains in the Genus database with same CATH superfamily
1F9TA 1MMAA 3K5EA 5LT2A 2X7CA 2X7EA 2G1QA 4FRZA 3WPNA 1RY6A 4PFOA 4PJNA 2FKYA 1G8XA 4ANJA 1BR4A 1SDMA 2PG2A 4E7ZA 3HQDA 4E7SA 1VFVA 3KINA 2FMEA 4A5YA 4GKQA 1CZ7A 3CJOA 2V26A 4ZHIA 4PJJA 4AP0A 2MYSA 2VASA 2WOGA 5LT4A 5LT1A 1I5SA 2XAEA 3L9HA 1KK7A 5GSZA 3H4SA 1VFWA 4GKPA 5LT0A 5LT3A 3L1CA 4BN2A 2Q2YA 1VFXA 3LREA 4BXNA 3PXNA 2X7DA 1GOJA 1MNEA 2X51A 2ZFIA 1FMVA 4A14A 4LNUK 2OWMA 2GRYA 3WRDA 3GBJA 2FL2A 3CNZA 2ZFKA 1D1BA 1VOMA 3B6UA 1II6A 5HLEA 2Q2ZA 4B7BA 1F9VA 1N6MA 1D0XA 1F9UA 1MMNA 2O0AA 3U06A 2IEHA 1LKXA 4PK4A 1YRSA 4HNAK 4Y05A 1Q0BA 3B6VA 3KARA 4ZCAA 3K3BA 1LVKA 4PFPA 2VVGA 1MKJA 2ZFMA 3T0QA 4DBRA 1D1CA 1F9WA 1MMGA 4GKRA 2X2RA 2FL6A 2NCDA 2ZFLA 2UYMA 1D0YA 3DCBA 4A28A 1V8JA 3ZCWA 4H1GA 4BBGA 2Y5WA 3NWNA 2KINA 4PJMA 3ZFCA 1MMDA 1BR2A 2UYIA 1D0ZA 2VB6A 2XT3A 4A50A 3ZFDA 2HEHA 4DBQA 1BG2A 4ETPA 2GM1A 3COBA 1X88A 4PJLA 4ETPB 2ZFJA 4UBFA 2Y65A 4A1ZA 4A51A 1T5CA 1VFZA 3BFNA 1D1AA 1BR1A 3X2TA 3DC4A 4AS7A 1FMWA 1I6IA 3KENA 1V8KA
chains in the Genus database with same CATH topology
1F9TA 1MMAA 3K5EA 5LT2A 2X7CA 2X7EA 2G1QA 4FRZA 3WPNA 1RY6A 4PFOA 4PJNA 2FKYA 1G8XA 4ANJA 1BR4A 1SDMA 2PG2A 4E7ZA 3HQDA 4E7SA 1VFVA 3KINA 2FMEA 4A5YA 1CZ7A 3CJOA 2V26A 4ZHIA 4PJJA 4AP0A 2MYSA 2VASA 2WOGA 5LT4A 5LT1A 1I5SA 2XAEA 3L9HA 1KK7A 5GSZA 3H4SA 1VFWA 5LT0A 5LT3A 3L1CA 4BN2A 2Q2YA 1VFXA 3LREA 4BXNA 3PXNA 2X7DA 1GOJA 1MNEA 2X51A 2ZFIA 1FMVA 4A14A 4LNUK 2OWMA 2GRYA 3WRDA 3GBJA 2FL2A 3CNZA 2ZFKA 1D1BA 1VOMA 3B6UA 1II6A 5HLEA 2Q2ZA 4B7BA 1F9VA 1N6MA 1D0XA 1F9UA 1MMNA 3U06A 2IEHA 1LKXA 4PK4A 1YRSA 4HNAK 4Y05A 1Q0BA 3B6VA 3KARA 4ZCAA 3K3BA 1LVKA 4PFPA 2VVGA 1MKJA 2ZFMA 3T0QA 4DBRA 1D1CA 1F9WA 1MMGA 4GKRA 2X2RA 2FL6A 2NCDA 2ZFLA 2UYMA 1D0YA 3DCBA 4A28A 1V8JA 3ZCWA 4H1GA 4BBGA 2Y5WA 3NWNA 2KINA 4PJMA 3ZFCA 1MMDA 1BR2A 2UYIA 1D0ZA 2VB6A 2XT3A 4A50A 3ZFDA 2HEHA 4DBQA 1BG2A 4ETPA 2GM1A 3COBA 1X88A 4PJLA 2ZFJA 4UBFA 2Y65A 4A1ZA 4A51A 1T5CA 1VFZA 3BFNA 1D1AA 1BR1A 3X2TA 3DC4A 4AS7A 1FMWA 1I6IA 3KENA 1V8KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1F9T A;  1MMA A;  3K5E A;  5LT2 A;  2X7C A;  2X7E A;  2G1Q A;  4FRZ A;  3WPN A;  1RY6 A;  4PFO A;  4PJN A;  2FKY A;  1G8X A;  4ANJ A;  1BR4 A;  1SDM A;  2PG2 A;  4E7Z A;  3HQD A;  4E7S A;  1VFV A;  3KIN A;  2FME A;  4A5Y A;  1CZ7 A;  3CJO A;  2V26 A;  4ZHI A;  4PJJ A;  4AP0 A;  2MYS A;  2VAS A;  2WOG A;  5LT4 A;  5LT1 A;  1I5S A;  2XAE A;  3L9H A;  1KK7 A;  5GSZ A;  3H4S A;  1VFW A;  5LT0 A;  5LT3 A;  3L1C A;  4BN2 A;  2Q2Y A;  1VFX A;  3LRE A;  4BXN A;  3PXN A;  2X7D A;  1GOJ A;  1MNE A;  2X51 A;  2ZFI A;  1FMV A;  4A14 A;  4LNU K;  2OWM A;  2GRY A;  3WRD A;  3GBJ A;  2FL2 A;  3CNZ A;  2ZFK A;  1D1B A;  1VOM A;  3B6U A;  1II6 A;  5HLE A;  2Q2Z A;  4B7B A;  1F9V A;  1N6M A;  1D0X A;  1F9U A;  1MMN A;  3U06 A;  2IEH A;  1LKX A;  4PK4 A;  1YRS A;  4HNA K;  4Y05 A;  1Q0B A;  3B6V A;  3KAR A;  4ZCA A;  3K3B A;  1LVK A;  4PFP A;  2VVG A;  1MKJ A;  2ZFM A;  3T0Q A;  4DBR A;  1D1C A;  1F9W A;  1MMG A;  4GKR A;  2X2R A;  2FL6 A;  2NCD A;  2ZFL A;  2UYM A;  1D0Y A;  3DCB A;  4A28 A;  1V8J A;  3ZCW A;  4H1G A;  4BBG A;  2Y5W A;  3NWN A;  2KIN A;  4PJM A;  3ZFC A;  1MMD A;  1BR2 A;  2UYI A;  1D0Z A;  2VB6 A;  2XT3 A;  4A50 A;  3ZFD A;  2HEH A;  4DBQ A;  1BG2 A;  4ETP A;  2GM1 A;  3COB A;  1X88 A;  4PJL A;  2ZFJ A;  4UBF A;  2Y65 A;  4A1Z A;  4A51 A;  1T5C A;  1VFZ A;  3BFN A;  1D1A A;  1BR1 A;  3X2T A;  3DC4 A;  4AS7 A;  1FMW A;  1I6I A;  3KEN A;  1V8K A; 
#chains in the Genus database with same CATH topology
 1F9T A;  1MMA A;  3K5E A;  5LT2 A;  2X7C A;  2X7E A;  2G1Q A;  4FRZ A;  3WPN A;  1RY6 A;  4PFO A;  4PJN A;  2FKY A;  1G8X A;  4ANJ A;  1BR4 A;  1SDM A;  2PG2 A;  4E7Z A;  3HQD A;  4E7S A;  1VFV A;  3KIN A;  2FME A;  4A5Y A;  4GKQ A;  1CZ7 A;  3CJO A;  2V26 A;  4ZHI A;  4PJJ A;  4AP0 A;  2MYS A;  2VAS A;  2WOG A;  5LT4 A;  5LT1 A;  1I5S A;  2XAE A;  3L9H A;  1KK7 A;  5GSZ A;  3H4S A;  1VFW A;  4GKP A;  5LT0 A;  5LT3 A;  3L1C A;  4BN2 A;  2Q2Y A;  1VFX A;  3LRE A;  4BXN A;  3PXN A;  2X7D A;  1GOJ A;  1MNE A;  2X51 A;  2ZFI A;  1FMV A;  4A14 A;  4LNU K;  2OWM A;  2GRY A;  3WRD A;  3GBJ A;  2FL2 A;  3CNZ A;  2ZFK A;  1D1B A;  1VOM A;  3B6U A;  1II6 A;  5HLE A;  2Q2Z A;  4B7B A;  1F9V A;  1N6M A;  1D0X A;  1F9U A;  1MMN A;  2O0A A;  3U06 A;  2IEH A;  1LKX A;  4PK4 A;  1YRS A;  4HNA K;  4Y05 A;  1Q0B A;  3B6V A;  3KAR A;  4ZCA A;  3K3B A;  1LVK A;  4PFP A;  2VVG A;  1MKJ A;  2ZFM A;  3T0Q A;  4DBR A;  1D1C A;  1F9W A;  1MMG A;  4GKR A;  2X2R A;  2FL6 A;  2NCD A;  2ZFL A;  2UYM A;  1D0Y A;  3DCB A;  4A28 A;  1V8J A;  3ZCW A;  4H1G A;  4BBG A;  2Y5W A;  3NWN A;  2KIN A;  4PJM A;  3ZFC A;  1MMD A;  1BR2 A;  2UYI A;  1D0Z A;  2VB6 A;  2XT3 A;  4A50 A;  3ZFD A;  2HEH A;  4DBQ A;  1BG2 A;  4ETP A;  2GM1 A;  3COB A;  1X88 A;  4PJL A;  4ETP B;  2ZFJ A;  4UBF A;  2Y65 A;  4A1Z A;  4A51 A;  1T5C A;  1VFZ A;  3BFN A;  1D1A A;  1BR1 A;  3X2T A;  3DC4 A;  4AS7 A;  1FMW A;  1I6I A;  3KEN A;  1V8K A; 
#chains in the Genus database with same CATH homology
 1F9T A;  1MMA A;  3K5E A;  5LT2 A;  2X7C A;  2X7E A;  2G1Q A;  4FRZ A;  3WPN A;  1RY6 A;  4PFO A;  4PJN A;  2FKY A;  1G8X A;  4ANJ A;  1BR4 A;  1SDM A;  2PG2 A;  4E7Z A;  3HQD A;  4E7S A;  1VFV A;  3KIN A;  2FME A;  4A5Y A;  1CZ7 A;  3CJO A;  2V26 A;  4ZHI A;  4PJJ A;  4AP0 A;  2MYS A;  2VAS A;  2WOG A;  5LT4 A;  5LT1 A;  1I5S A;  2XAE A;  3L9H A;  1KK7 A;  5GSZ A;  3H4S A;  1VFW A;  5LT0 A;  5LT3 A;  3L1C A;  4BN2 A;  2Q2Y A;  1VFX A;  3LRE A;  4BXN A;  3PXN A;  2X7D A;  1GOJ A;  1MNE A;  2X51 A;  2ZFI A;  1FMV A;  4A14 A;  4LNU K;  2OWM A;  2GRY A;  3WRD A;  3GBJ A;  2FL2 A;  3CNZ A;  2ZFK A;  1D1B A;  1VOM A;  3B6U A;  1II6 A;  5HLE A;  2Q2Z A;  4B7B A;  1F9V A;  1N6M A;  1D0X A;  1F9U A;  1MMN A;  3U06 A;  2IEH A;  1LKX A;  4PK4 A;  1YRS A;  4HNA K;  4Y05 A;  1Q0B A;  3B6V A;  3KAR A;  4ZCA A;  3K3B A;  1LVK A;  4PFP A;  2VVG A;  1MKJ A;  2ZFM A;  3T0Q A;  4DBR A;  1D1C A;  1F9W A;  1MMG A;  4GKR A;  2X2R A;  2FL6 A;  2NCD A;  2ZFL A;  2UYM A;  1D0Y A;  3DCB A;  4A28 A;  1V8J A;  3ZCW A;  4H1G A;  4BBG A;  2Y5W A;  3NWN A;  2KIN A;  4PJM A;  3ZFC A;  1MMD A;  1BR2 A;  2UYI A;  1D0Z A;  2VB6 A;  2XT3 A;  4A50 A;  3ZFD A;  2HEH A;  4DBQ A;  1BG2 A;  4ETP A;  2GM1 A;  3COB A;  1X88 A;  4PJL A;  2ZFJ A;  4UBF A;  2Y65 A;  4A1Z A;  4A51 A;  1T5C A;  1VFZ A;  3BFN A;  1D1A A;  1BR1 A;  3X2T A;  3DC4 A;  4AS7 A;  1FMW A;  1I6I A;  3KEN A;  1V8K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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