5HLE | Genus

Total Genus 83

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	83
sequence length	321
structure length	303
Chain Sequence	NTVMDLRGNIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFAIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKSNRHVAEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVKNINKSLSALGNVISALAEGTTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFAA

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Drosophila melanogaster
publication title	Backwards motion in kinesin-14 requires neck-mimic to control a neck-helix swing. rcsb
molecule keywords	Protein claret segregational,Minus-end kinesin-1/kinesin-14,
total genus	83
structure length	303
sequence length	321
ec nomenclature
pdb deposition date	2016-01-14

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.850.10	Alpha Beta	3-Layer(aba) Sandwich	Kinesin	Kinesin motor domain	5hleA00

2ZFMA 4H1GA 1BR1A 1VFVA 4ZHIA 3KARA 4ETPA 1CZ7A 3T0QA 4E7ZA 3B6UA 4UBFA 5LT3A 3NWNA 3L1CA 2X2RA 2XT3A 3K3BA 4BBGA 3WPNA 1MMNA 2NCDA 2ZFLA 1MNEA 3CJOA 4DBQA 4PK4A 4FRZA 3PXNA 5LT4A 3BFNA 5LT0A 2Y5WA 2OWMA 1G8XA 3ZCWA 2UYMA 4ANJA 4E7SA 1VOMA 4A50A 3KINA 1MMAA 2GRYA 1D1AA 3DCBA 3K5EA 4BN2A 1LVKA 1SDMA 3KENA 3DC4A 1F9UA 4LNUK 5LT2A 1I5SA 3B6VA 2Q2YA 2FL6A 1VFWA 2X7EA 1D0YA 1RY6A 1T5CA 4PJMA 4PJJA 4A5YA 1D0ZA 1I6IA 3HQDA 1VFXA 2VVGA 4AS7A 4GKRA 3X2TA 4A28A 2HEHA 2MYSA 2GM1A 1BR2A 4PFPA 4B7BA 3LREA 2XAEA 1Q0BA 3H4SA 2IEHA 4BXNA 1V8KA 2KINA 1X88A 2PG2A 2UYIA 2ZFKA 1MKJA 2X7CA 1V8JA 1N6MA 3L9HA 1II6A 1VFZA 2G1QA 1D0XA 3ZFDA 5LT1A 4HNAK 4PJNA 3CNZA 2FKYA 2ZFIA 1GOJA 2Q2ZA 2VB6A 3COBA 1MMGA 1BG2A 1YRSA 4AP0A 4Y05A 1FMWA 1FMVA 2WOGA 1F9TA 4PJLA 3GBJA 4ZCAA 2Y65A 2VASA 3ZFCA 4A1ZA 2FMEA 3WRDA 1LKXA 4A51A 4DBRA 2X51A 1KK7A 5GSZA 2V26A 1F9VA 1MMDA 2ZFJA 1BR4A 5HLEA 3U06A 4A14A 1D1CA 1F9WA 2FL2A 1D1BA 4PFOA 2X7DA
chains in the Genus database with same CATH superfamily

2ZFMA 4H1GA 4GKQA 1BR1A 1VFVA 4ZHIA 3KARA 4ETPA 1CZ7A 3T0QA 4E7ZA 3B6UA 4UBFA 5LT3A 3NWNA 3L1CA 2X2RA 2XT3A 3K3BA 4BBGA 3WPNA 1MMNA 2NCDA 2ZFLA 1MNEA 3CJOA 4DBQA 4PK4A 4FRZA 3PXNA 5LT4A 3BFNA 5LT0A 2Y5WA 2OWMA 1G8XA 3ZCWA 2UYMA 4ANJA 4E7SA 1VOMA 4A50A 3KINA 1MMAA 2GRYA 1D1AA 3DCBA 3K5EA 4BN2A 1LVKA 1SDMA 3KENA 3DC4A 1F9UA 4LNUK 5LT2A 1I5SA 3B6VA 2Q2YA 2FL6A 1VFWA 2X7EA 1D0YA 1RY6A 1T5CA 4PJMA 4PJJA 4A5YA 1D0ZA 1I6IA 3HQDA 1VFXA 2VVGA 4AS7A 4GKRA 3X2TA 4A28A 2O0AA 2HEHA 2MYSA 2GM1A 1BR2A 4PFPA 4B7BA 3LREA 2XAEA 1Q0BA 3H4SA 2IEHA 4BXNA 1V8KA 2KINA 1X88A 2PG2A 2UYIA 2ZFKA 1MKJA 2X7CA 1V8JA 1N6MA 3L9HA 1II6A 1VFZA 2G1QA 1D0XA 3ZFDA 5LT1A 4HNAK 4PJNA 3CNZA 2FKYA 2ZFIA 1GOJA 2Q2ZA 2VB6A 3COBA 1MMGA 1BG2A 1YRSA 4AP0A 4Y05A 1FMWA 1FMVA 2WOGA 1F9TA 4PJLA 3GBJA 4ZCAA 2Y65A 2VASA 3ZFCA 4GKPA 4ETPB 4A1ZA 2FMEA 3WRDA 1LKXA 4A51A 4DBRA 2X51A 1KK7A 5GSZA 2V26A 1F9VA 1MMDA 2ZFJA 1BR4A 5HLEA 3U06A 4A14A 1D1CA 1F9WA 2FL2A 1D1BA 4PFOA 2X7DA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2ZFM A;  4H1G A;  1BR1 A;  1VFV A;  4ZHI A;  3KAR A;  4ETP A;  1CZ7 A;  3T0Q A;  4E7Z A;  3B6U A;  4UBF A;  5LT3 A;  3NWN A;  3L1C A;  2X2R A;  2XT3 A;  3K3B A;  4BBG A;  3WPN A;  1MMN A;  2NCD A;  2ZFL A;  1MNE A;  3CJO A;  4DBQ A;  4PK4 A;  4FRZ A;  3PXN A;  5LT4 A;  3BFN A;  5LT0 A;  2Y5W A;  2OWM A;  1G8X A;  3ZCW A;  2UYM A;  4ANJ A;  4E7S A;  1VOM A;  4A50 A;  3KIN A;  1MMA A;  2GRY A;  1D1A A;  3DCB A;  3K5E A;  4BN2 A;  1LVK A;  1SDM A;  3KEN A;  3DC4 A;  1F9U A;  4LNU K;  5LT2 A;  1I5S A;  3B6V A;  2Q2Y A;  2FL6 A;  1VFW A;  2X7E A;  1D0Y A;  1RY6 A;  1T5C A;  4PJM A;  4PJJ A;  4A5Y A;  1D0Z A;  1I6I A;  3HQD A;  1VFX A;  2VVG A;  4AS7 A;  4GKR A;  3X2T A;  4A28 A;  2HEH A;  2MYS A;  2GM1 A;  1BR2 A;  4PFP A;  4B7B A;  3LRE A;  2XAE A;  1Q0B A;  3H4S A;  2IEH A;  4BXN A;  1V8K A;  2KIN A;  1X88 A;  2PG2 A;  2UYI A;  2ZFK A;  1MKJ A;  2X7C A;  1V8J A;  1N6M A;  3L9H A;  1II6 A;  1VFZ A;  2G1Q A;  1D0X A;  3ZFD A;  5LT1 A;  4HNA K;  4PJN A;  3CNZ A;  2FKY A;  2ZFI A;  1GOJ A;  2Q2Z A;  2VB6 A;  3COB A;  1MMG A;  1BG2 A;  1YRS A;  4AP0 A;  4Y05 A;  1FMW A;  1FMV A;  2WOG A;  1F9T A;  4PJL A;  3GBJ A;  4ZCA A;  2Y65 A;  2VAS A;  3ZFC A;  4A1Z A;  2FME A;  3WRD A;  1LKX A;  4A51 A;  4DBR A;  2X51 A;  1KK7 A;  5GSZ A;  2V26 A;  1F9V A;  1MMD A;  2ZFJ A;  1BR4 A;  5HLE A;  3U06 A;  4A14 A;  1D1C A;  1F9W A;  2FL2 A;  1D1B A;  4PFO A;  2X7D A; 
#chains in the Genus database with same CATH topology
 2ZFM A;  4H1G A;  4GKQ A;  1BR1 A;  1VFV A;  4ZHI A;  3KAR A;  4ETP A;  1CZ7 A;  3T0Q A;  4E7Z A;  3B6U A;  4UBF A;  5LT3 A;  3NWN A;  3L1C A;  2X2R A;  2XT3 A;  3K3B A;  4BBG A;  3WPN A;  1MMN A;  2NCD A;  2ZFL A;  1MNE A;  3CJO A;  4DBQ A;  4PK4 A;  4FRZ A;  3PXN A;  5LT4 A;  3BFN A;  5LT0 A;  2Y5W A;  2OWM A;  1G8X A;  3ZCW A;  2UYM A;  4ANJ A;  4E7S A;  1VOM A;  4A50 A;  3KIN A;  1MMA A;  2GRY A;  1D1A A;  3DCB A;  3K5E A;  4BN2 A;  1LVK A;  1SDM A;  3KEN A;  3DC4 A;  1F9U A;  4LNU K;  5LT2 A;  1I5S A;  3B6V A;  2Q2Y A;  2FL6 A;  1VFW A;  2X7E A;  1D0Y A;  1RY6 A;  1T5C A;  4PJM A;  4PJJ A;  4A5Y A;  1D0Z A;  1I6I A;  3HQD A;  1VFX A;  2VVG A;  4AS7 A;  4GKR A;  3X2T A;  4A28 A;  2O0A A;  2HEH A;  2MYS A;  2GM1 A;  1BR2 A;  4PFP A;  4B7B A;  3LRE A;  2XAE A;  1Q0B A;  3H4S A;  2IEH A;  4BXN A;  1V8K A;  2KIN A;  1X88 A;  2PG2 A;  2UYI A;  2ZFK A;  1MKJ A;  2X7C A;  1V8J A;  1N6M A;  3L9H A;  1II6 A;  1VFZ A;  2G1Q A;  1D0X A;  3ZFD A;  5LT1 A;  4HNA K;  4PJN A;  3CNZ A;  2FKY A;  2ZFI A;  1GOJ A;  2Q2Z A;  2VB6 A;  3COB A;  1MMG A;  1BG2 A;  1YRS A;  4AP0 A;  4Y05 A;  1FMW A;  1FMV A;  2WOG A;  1F9T A;  4PJL A;  3GBJ A;  4ZCA A;  2Y65 A;  2VAS A;  3ZFC A;  4GKP A;  4ETP B;  4A1Z A;  2FME A;  3WRD A;  1LKX A;  4A51 A;  4DBR A;  2X51 A;  1KK7 A;  5GSZ A;  2V26 A;  1F9V A;  1MMD A;  2ZFJ A;  1BR4 A;  5HLE A;  3U06 A;  4A14 A;  1D1C A;  1F9W A;  2FL2 A;  1D1B A;  4PFO A;  2X7D A; 
#chains in the Genus database with same CATH homology
 2ZFM A;  4H1G A;  1BR1 A;  1VFV A;  4ZHI A;  3KAR A;  4ETP A;  1CZ7 A;  3T0Q A;  4E7Z A;  3B6U A;  4UBF A;  5LT3 A;  3NWN A;  3L1C A;  2X2R A;  2XT3 A;  3K3B A;  4BBG A;  3WPN A;  1MMN A;  2NCD A;  2ZFL A;  1MNE A;  3CJO A;  4DBQ A;  4PK4 A;  4FRZ A;  3PXN A;  5LT4 A;  3BFN A;  5LT0 A;  2Y5W A;  2OWM A;  1G8X A;  3ZCW A;  2UYM A;  4ANJ A;  4E7S A;  1VOM A;  4A50 A;  3KIN A;  1MMA A;  2GRY A;  1D1A A;  3DCB A;  3K5E A;  4BN2 A;  1LVK A;  1SDM A;  3KEN A;  3DC4 A;  1F9U A;  4LNU K;  5LT2 A;  1I5S A;  3B6V A;  2Q2Y A;  2FL6 A;  1VFW A;  2X7E A;  1D0Y A;  1RY6 A;  1T5C A;  4PJM A;  4PJJ A;  4A5Y A;  1D0Z A;  1I6I A;  3HQD A;  1VFX A;  2VVG A;  4AS7 A;  4GKR A;  3X2T A;  4A28 A;  2HEH A;  2MYS A;  2GM1 A;  1BR2 A;  4PFP A;  4B7B A;  3LRE A;  2XAE A;  1Q0B A;  3H4S A;  2IEH A;  4BXN A;  1V8K A;  2KIN A;  1X88 A;  2PG2 A;  2UYI A;  2ZFK A;  1MKJ A;  2X7C A;  1V8J A;  1N6M A;  3L9H A;  1II6 A;  1VFZ A;  2G1Q A;  1D0X A;  3ZFD A;  5LT1 A;  4HNA K;  4PJN A;  3CNZ A;  2FKY A;  2ZFI A;  1GOJ A;  2Q2Z A;  2VB6 A;  3COB A;  1MMG A;  1BG2 A;  1YRS A;  4AP0 A;  4Y05 A;  1FMW A;  1FMV A;  2WOG A;  1F9T A;  4PJL A;  3GBJ A;  4ZCA A;  2Y65 A;  2VAS A;  3ZFC A;  4A1Z A;  2FME A;  3WRD A;  1LKX A;  4A51 A;  4DBR A;  2X51 A;  1KK7 A;  5GSZ A;  2V26 A;  1F9V A;  1MMD A;  2ZFJ A;  1BR4 A;  5HLE A;  3U06 A;  4A14 A;  1D1C A;  1F9W A;  2FL2 A;  1D1B A;  4PFO A;  2X7D A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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5HLEA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN