5LT1A

Nucleotide-free kinesin-1 motor domain t92v mutant, p21 crystal form
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
318
structure length
309
Chain Sequence
SNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDAAKKIVKDVLEGYNGTIFAYGQTSSGKVHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGATERFVSSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNARTTIVICCSPSSYNESETKSTLLFGQRAKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structural switch of nucleotide-free kinesin.
pubmed doi rcsb
molecule tags Motor protein
source organism Homo sapiens
molecule keywords Kinesin-like protein
total genus 108
structure length 309
sequence length 318
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-09-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00225 Kinesin Kinesin motor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.850.10 Alpha Beta 3-Layer(aba) Sandwich Kinesin Kinesin motor domain 5lt1A00
4BN2A 2V26A 3X2TA 3ZCWA 3ZFDA 2HEHA 1D1AA 2VVGA 4A28A 4UBFA 3HQDA 2G1QA 1VFWA 1F9VA 1LKXA 5HLEA 1MMNA 2GM1A 3DCBA 2VB6A 2FL6A 2ZFLA 1G8XA 1VFZA 1MMGA 3ZFCA 2UYMA 2XAEA 2X7DA 4PJMA 4PFOA 3T0QA 5LT4A 3K5EA 3KENA 3KARA 1SDMA 3H4SA 3BFNA 2OWMA 1VFVA 1BR2A 4A50A 1V8JA 1V8KA 2GRYA 3PXNA 5LT1A 4FRZA 1N6MA 4PFPA 2X7EA 4PJJA 1D0ZA 4BBGA 4ANJA 2Y65A 1FMWA 4H1GA 2VASA 2IEHA 1D1BA 5LT2A 4E7ZA 4A1ZA 3COBA 4BXNA 2Q2ZA 3WRDA 4E7SA 2Q2YA 3B6UA 1T5CA 1GOJA 5LT0A 1RY6A 1D0YA 1BG2A 2Y5WA 4A14A 1X88A 1MNEA 1CZ7A 1F9UA 4AS7A 4DBQA 1D0XA 3KINA 2X51A 1KK7A 3CJOA 2ZFIA 4AP0A 2X2RA 3U06A 1Q0BA 4ZHIA 1VOMA 1MMDA 4Y05A 2XT3A 1II6A 4HNAK 4DBRA 1I6IA 4ZCAA 3B6VA 1F9WA 1MKJA 2KINA 1YRSA 2NCDA 2ZFJA 4LNUK 2MYSA 3NWNA 4GKRA 1LVKA 2ZFKA 3L9HA 2FKYA 3LREA 1D1CA 1BR4A 3DC4A 2WOGA 4PK4A 2ZFMA 4A5YA 5LT3A 2PG2A 2UYIA 4ETPA 5GSZA 2FMEA 3GBJA 1BR1A 1MMAA 3CNZA 4B7BA 1FMVA 2X7CA 4PJLA 4PJNA 1F9TA 3L1CA 2FL2A 1I5SA 1VFXA 3K3BA 3WPNA 4A51A
chains in the Genus database with same CATH superfamily
4BN2A 2V26A 3X2TA 3ZCWA 2O0AA 3ZFDA 2HEHA 1D1AA 2VVGA 4A28A 4UBFA 3HQDA 2G1QA 1VFWA 1F9VA 1LKXA 5HLEA 1MMNA 2GM1A 3DCBA 2VB6A 2FL6A 2ZFLA 1G8XA 1VFZA 1MMGA 3ZFCA 2UYMA 2XAEA 2X7DA 4PJMA 4PFOA 3T0QA 5LT4A 3K5EA 3KENA 3KARA 1SDMA 3H4SA 3BFNA 2OWMA 1VFVA 1BR2A 4A50A 1V8JA 1V8KA 2GRYA 4GKPA 3PXNA 5LT1A 4FRZA 1N6MA 4PFPA 2X7EA 4PJJA 1D0ZA 4BBGA 4ANJA 2Y65A 1FMWA 4H1GA 2VASA 2IEHA 1D1BA 5LT2A 4E7ZA 4A1ZA 3COBA 4BXNA 2Q2ZA 3WRDA 4E7SA 2Q2YA 3B6UA 1T5CA 1GOJA 5LT0A 1RY6A 1D0YA 1BG2A 2Y5WA 4A14A 1X88A 1MNEA 1CZ7A 1F9UA 4AS7A 4DBQA 1D0XA 3KINA 2X51A 1KK7A 3CJOA 2ZFIA 4AP0A 2X2RA 3U06A 1Q0BA 4ZHIA 1VOMA 1MMDA 4Y05A 2XT3A 1II6A 4HNAK 4DBRA 4ETPB 1I6IA 4ZCAA 3B6VA 4GKQA 1F9WA 1MKJA 2KINA 1YRSA 2NCDA 2ZFJA 4LNUK 2MYSA 3NWNA 4GKRA 1LVKA 2ZFKA 3L9HA 2FKYA 3LREA 1D1CA 1BR4A 3DC4A 2WOGA 4PK4A 2ZFMA 4A5YA 5LT3A 2PG2A 2UYIA 4ETPA 5GSZA 2FMEA 3GBJA 1BR1A 1MMAA 3CNZA 4B7BA 1FMVA 2X7CA 4PJLA 4PJNA 1F9TA 3L1CA 2FL2A 1I5SA 1VFXA 3K3BA 3WPNA 4A51A
chains in the Genus database with same CATH topology
4BN2A 2V26A 3X2TA 3ZCWA 3ZFDA 2HEHA 1D1AA 2VVGA 4A28A 4UBFA 3HQDA 2G1QA 1VFWA 1F9VA 1LKXA 5HLEA 1MMNA 2GM1A 3DCBA 2VB6A 2FL6A 2ZFLA 1G8XA 1VFZA 1MMGA 3ZFCA 2UYMA 2XAEA 2X7DA 4PJMA 4PFOA 3T0QA 5LT4A 3K5EA 3KENA 3KARA 1SDMA 3H4SA 3BFNA 2OWMA 1VFVA 1BR2A 4A50A 1V8JA 1V8KA 2GRYA 3PXNA 5LT1A 4FRZA 1N6MA 4PFPA 2X7EA 4PJJA 1D0ZA 4BBGA 4ANJA 2Y65A 1FMWA 4H1GA 2VASA 2IEHA 1D1BA 5LT2A 4E7ZA 4A1ZA 3COBA 4BXNA 2Q2ZA 3WRDA 4E7SA 2Q2YA 3B6UA 1T5CA 1GOJA 5LT0A 1RY6A 1D0YA 1BG2A 2Y5WA 4A14A 1X88A 1MNEA 1CZ7A 1F9UA 4AS7A 4DBQA 1D0XA 3KINA 2X51A 1KK7A 3CJOA 2ZFIA 4AP0A 2X2RA 3U06A 1Q0BA 4ZHIA 1VOMA 1MMDA 4Y05A 2XT3A 1II6A 4HNAK 4DBRA 1I6IA 4ZCAA 3B6VA 1F9WA 1MKJA 2KINA 1YRSA 2NCDA 2ZFJA 4LNUK 2MYSA 3NWNA 4GKRA 1LVKA 2ZFKA 3L9HA 2FKYA 3LREA 1D1CA 1BR4A 3DC4A 2WOGA 4PK4A 2ZFMA 4A5YA 5LT3A 2PG2A 2UYIA 4ETPA 5GSZA 2FMEA 3GBJA 1BR1A 1MMAA 3CNZA 4B7BA 1FMVA 2X7CA 4PJLA 4PJNA 1F9TA 3L1CA 2FL2A 1I5SA 1VFXA 3K3BA 3WPNA 4A51A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BN2 A;  2V26 A;  3X2T A;  3ZCW A;  3ZFD A;  2HEH A;  1D1A A;  2VVG A;  4A28 A;  4UBF A;  3HQD A;  2G1Q A;  1VFW A;  1F9V A;  1LKX A;  5HLE A;  1MMN A;  2GM1 A;  3DCB A;  2VB6 A;  2FL6 A;  2ZFL A;  1G8X A;  1VFZ A;  1MMG A;  3ZFC A;  2UYM A;  2XAE A;  2X7D A;  4PJM A;  4PFO A;  3T0Q A;  5LT4 A;  3K5E A;  3KEN A;  3KAR A;  1SDM A;  3H4S A;  3BFN A;  2OWM A;  1VFV A;  1BR2 A;  4A50 A;  1V8J A;  1V8K A;  2GRY A;  3PXN A;  5LT1 A;  4FRZ A;  1N6M A;  4PFP A;  2X7E A;  4PJJ A;  1D0Z A;  4BBG A;  4ANJ A;  2Y65 A;  1FMW A;  4H1G A;  2VAS A;  2IEH A;  1D1B A;  5LT2 A;  4E7Z A;  4A1Z A;  3COB A;  4BXN A;  2Q2Z A;  3WRD A;  4E7S A;  2Q2Y A;  3B6U A;  1T5C A;  1GOJ A;  5LT0 A;  1RY6 A;  1D0Y A;  1BG2 A;  2Y5W A;  4A14 A;  1X88 A;  1MNE A;  1CZ7 A;  1F9U A;  4AS7 A;  4DBQ A;  1D0X A;  3KIN A;  2X51 A;  1KK7 A;  3CJO A;  2ZFI A;  4AP0 A;  2X2R A;  3U06 A;  1Q0B A;  4ZHI A;  1VOM A;  1MMD A;  4Y05 A;  2XT3 A;  1II6 A;  4HNA K;  4DBR A;  1I6I A;  4ZCA A;  3B6V A;  1F9W A;  1MKJ A;  2KIN A;  1YRS A;  2NCD A;  2ZFJ A;  4LNU K;  2MYS A;  3NWN A;  4GKR A;  1LVK A;  2ZFK A;  3L9H A;  2FKY A;  3LRE A;  1D1C A;  1BR4 A;  3DC4 A;  2WOG A;  4PK4 A;  2ZFM A;  4A5Y A;  5LT3 A;  2PG2 A;  2UYI A;  4ETP A;  5GSZ A;  2FME A;  3GBJ A;  1BR1 A;  1MMA A;  3CNZ A;  4B7B A;  1FMV A;  2X7C A;  4PJL A;  4PJN A;  1F9T A;  3L1C A;  2FL2 A;  1I5S A;  1VFX A;  3K3B A;  3WPN A;  4A51 A; 
#chains in the Genus database with same CATH topology
 4BN2 A;  2V26 A;  3X2T A;  3ZCW A;  2O0A A;  3ZFD A;  2HEH A;  1D1A A;  2VVG A;  4A28 A;  4UBF A;  3HQD A;  2G1Q A;  1VFW A;  1F9V A;  1LKX A;  5HLE A;  1MMN A;  2GM1 A;  3DCB A;  2VB6 A;  2FL6 A;  2ZFL A;  1G8X A;  1VFZ A;  1MMG A;  3ZFC A;  2UYM A;  2XAE A;  2X7D A;  4PJM A;  4PFO A;  3T0Q A;  5LT4 A;  3K5E A;  3KEN A;  3KAR A;  1SDM A;  3H4S A;  3BFN A;  2OWM A;  1VFV A;  1BR2 A;  4A50 A;  1V8J A;  1V8K A;  2GRY A;  4GKP A;  3PXN A;  5LT1 A;  4FRZ A;  1N6M A;  4PFP A;  2X7E A;  4PJJ A;  1D0Z A;  4BBG A;  4ANJ A;  2Y65 A;  1FMW A;  4H1G A;  2VAS A;  2IEH A;  1D1B A;  5LT2 A;  4E7Z A;  4A1Z A;  3COB A;  4BXN A;  2Q2Z A;  3WRD A;  4E7S A;  2Q2Y A;  3B6U A;  1T5C A;  1GOJ A;  5LT0 A;  1RY6 A;  1D0Y A;  1BG2 A;  2Y5W A;  4A14 A;  1X88 A;  1MNE A;  1CZ7 A;  1F9U A;  4AS7 A;  4DBQ A;  1D0X A;  3KIN A;  2X51 A;  1KK7 A;  3CJO A;  2ZFI A;  4AP0 A;  2X2R A;  3U06 A;  1Q0B A;  4ZHI A;  1VOM A;  1MMD A;  4Y05 A;  2XT3 A;  1II6 A;  4HNA K;  4DBR A;  4ETP B;  1I6I A;  4ZCA A;  3B6V A;  4GKQ A;  1F9W A;  1MKJ A;  2KIN A;  1YRS A;  2NCD A;  2ZFJ A;  4LNU K;  2MYS A;  3NWN A;  4GKR A;  1LVK A;  2ZFK A;  3L9H A;  2FKY A;  3LRE A;  1D1C A;  1BR4 A;  3DC4 A;  2WOG A;  4PK4 A;  2ZFM A;  4A5Y A;  5LT3 A;  2PG2 A;  2UYI A;  4ETP A;  5GSZ A;  2FME A;  3GBJ A;  1BR1 A;  1MMA A;  3CNZ A;  4B7B A;  1FMV A;  2X7C A;  4PJL A;  4PJN A;  1F9T A;  3L1C A;  2FL2 A;  1I5S A;  1VFX A;  3K3B A;  3WPN A;  4A51 A; 
#chains in the Genus database with same CATH homology
 4BN2 A;  2V26 A;  3X2T A;  3ZCW A;  3ZFD A;  2HEH A;  1D1A A;  2VVG A;  4A28 A;  4UBF A;  3HQD A;  2G1Q A;  1VFW A;  1F9V A;  1LKX A;  5HLE A;  1MMN A;  2GM1 A;  3DCB A;  2VB6 A;  2FL6 A;  2ZFL A;  1G8X A;  1VFZ A;  1MMG A;  3ZFC A;  2UYM A;  2XAE A;  2X7D A;  4PJM A;  4PFO A;  3T0Q A;  5LT4 A;  3K5E A;  3KEN A;  3KAR A;  1SDM A;  3H4S A;  3BFN A;  2OWM A;  1VFV A;  1BR2 A;  4A50 A;  1V8J A;  1V8K A;  2GRY A;  3PXN A;  5LT1 A;  4FRZ A;  1N6M A;  4PFP A;  2X7E A;  4PJJ A;  1D0Z A;  4BBG A;  4ANJ A;  2Y65 A;  1FMW A;  4H1G A;  2VAS A;  2IEH A;  1D1B A;  5LT2 A;  4E7Z A;  4A1Z A;  3COB A;  4BXN A;  2Q2Z A;  3WRD A;  4E7S A;  2Q2Y A;  3B6U A;  1T5C A;  1GOJ A;  5LT0 A;  1RY6 A;  1D0Y A;  1BG2 A;  2Y5W A;  4A14 A;  1X88 A;  1MNE A;  1CZ7 A;  1F9U A;  4AS7 A;  4DBQ A;  1D0X A;  3KIN A;  2X51 A;  1KK7 A;  3CJO A;  2ZFI A;  4AP0 A;  2X2R A;  3U06 A;  1Q0B A;  4ZHI A;  1VOM A;  1MMD A;  4Y05 A;  2XT3 A;  1II6 A;  4HNA K;  4DBR A;  1I6I A;  4ZCA A;  3B6V A;  1F9W A;  1MKJ A;  2KIN A;  1YRS A;  2NCD A;  2ZFJ A;  4LNU K;  2MYS A;  3NWN A;  4GKR A;  1LVK A;  2ZFK A;  3L9H A;  2FKY A;  3LRE A;  1D1C A;  1BR4 A;  3DC4 A;  2WOG A;  4PK4 A;  2ZFM A;  4A5Y A;  5LT3 A;  2PG2 A;  2UYI A;  4ETP A;  5GSZ A;  2FME A;  3GBJ A;  1BR1 A;  1MMA A;  3CNZ A;  4B7B A;  1FMV A;  2X7C A;  4PJL A;  4PJN A;  1F9T A;  3L1C A;  2FL2 A;  1I5S A;  1VFX A;  3K3B A;  3WPN A;  4A51 A; 
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similar chains in the pdb database (?% sequence similarity)

 
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