1Z9EA

Solution structure of the hiv-1 integrase-binding domain in ledgf/p75
Total Genus 24

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
83
structure length
83
Chain Sequence
SMDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLV

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
molecule tags Protein binding/transcription
source organism Homo sapiens
publication title Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75
pubmed doi rcsb
molecule keywords PC4 and SFRS1 interacting protein 2
total genus 24
structure length 83
sequence length 83
ec nomenclature
pdb deposition date 2005-04-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11467 LEDGF Lens epithelium-derived growth factor (LEDGF)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.10 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 1z9eA00
2XPPA 2XPLA 3O8ZA 2N3AB 2XPNA 3U88C 2XPOA 1EO0A 3OAKA 1Z9EA 1WJTA 3HPHE 3HPGG 3NFQA 2B4JC 3F9KC
chains in the Genus database with same CATH superfamily
2DLAA 3BXMA 3VROA 1WJTA 3FF3A 2OOTA 2B4JC 5F13A 4P4JA 3BUMB 3OB2B 2OR4A 1EO0A 1Z9EA 4P4EA 5ELYA 4MCQA 3FEDA 3S9NA 2PVWA 3D7DA 4A4BA 4GPLB 4OC5A 3BI1A 3PFVA 3D7HA 4OC3A 4NGNA 4NGMA 4BPUB 3VGOA 2XEFA 3SJXA 3BHXA 3VRPA 4NGRA 3OB1B 4NGPA 3IWWA 4W9YA 4MCRA 5HKWA 1Z8LA 2UV8G 1YVHA 2VKZG 2XPNA 4NGQA 3SJFA 3U88C 2XPOA 3OAKA 4BPXB 4P4DA 4RR2B 5HKYA 1FBVA 5AXIA 3OP0A 4P4BA 4JYWA 4NGSA 4OC1A 2Y1MA 2XPPA 2XPLA 5J3XA 3RBUA 3BUWB 2C6PA 4A4CA 3HPHE 4OC4A 3HMJG 5HKZA 2XEGA 4OC2A 3VRNA 3PT1A 3KASA 4P4FA 3D7GA 4MCSA 2N3AB 4P45A 3VRQA 3O8ZA 3SJGA 2JBKA 2Y1NA 1B47A 2CBLA 3FEEA 3S9MA 4LQGA 1DE4C 3NFQA 2PVVA 3SJEA 5F09A 1CX8A 4OC0A 5BY0A 3HPGG 3F9KC 2XEIA 3BUNB 3D7FA 2C6GA 4MCPA 2C6CA 3FECA 3ZNIA 4BTFA 4NGTA 2XEJA 3S9LA 2CIJA 4OMEA 4JZ0A 3BUXB 4P44A 4P4IA 4BPWB 3VRRA 3BI0A 2JBJA 5D29A 3PLFB 3BUOB 4X3RA
chains in the Genus database with same CATH topology
2XPPA 2XPLA 3O8ZA 2N3AB 2XPNA 3U88C 2XPOA 1EO0A 3OAKA 1Z9EA 1WJTA 3HPHE 3HPGG 3NFQA 2B4JC 3F9KC
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2XPP A;  2XPL A;  3O8Z A;  2N3A B;  2XPN A;  3U88 C;  2XPO A;  1EO0 A;  3OAK A;  1Z9E A;  1WJT A;  3HPH E;  3HPG G;  3NFQ A;  2B4J C;  3F9K C; 
#chains in the Genus database with same CATH topology
 2DLA A;  3BXM A;  3VRO A;  1WJT A;  3FF3 A;  2OOT A;  2B4J C;  5F13 A;  4P4J A;  3BUM B;  3OB2 B;  2OR4 A;  1EO0 A;  1Z9E A;  4P4E A;  5ELY A;  4MCQ A;  3FED A;  3S9N A;  2PVW A;  3D7D A;  4A4B A;  4GPL B;  4OC5 A;  3BI1 A;  3PFV A;  3D7H A;  4OC3 A;  4NGN A;  4NGM A;  4BPU B;  3VGO A;  2XEF A;  3SJX A;  3BHX A;  3VRP A;  4NGR A;  3OB1 B;  4NGP A;  3IWW A;  4W9Y A;  4MCR A;  5HKW A;  1Z8L A;  2UV8 G;  1YVH A;  2VKZ G;  2XPN A;  4NGQ A;  3SJF A;  3U88 C;  2XPO A;  3OAK A;  4BPX B;  4P4D A;  4RR2 B;  5HKY A;  1FBV A;  5AXI A;  3OP0 A;  4P4B A;  4JYW A;  4NGS A;  4OC1 A;  2Y1M A;  2XPP A;  2XPL A;  5J3X A;  3RBU A;  3BUW B;  2C6P A;  4A4C A;  3HPH E;  4OC4 A;  3HMJ G;  5HKZ A;  2XEG A;  4OC2 A;  3VRN A;  3PT1 A;  3KAS A;  4P4F A;  3D7G A;  4MCS A;  2N3A B;  4P45 A;  3VRQ A;  3O8Z A;  3SJG A;  2JBK A;  2Y1N A;  1B47 A;  2CBL A;  3FEE A;  3S9M A;  4LQG A;  1DE4 C;  3NFQ A;  2PVV A;  3SJE A;  5F09 A;  1CX8 A;  4OC0 A;  5BY0 A;  3HPG G;  3F9K C;  2XEI A;  3BUN B;  3D7F A;  2C6G A;  4MCP A;  2C6C A;  3FEC A;  3ZNI A;  4BTF A;  4NGT A;  2XEJ A;  3S9L A;  2CIJ A;  4OME A;  4JZ0 A;  3BUX B;  4P44 A;  4P4I A;  4BPW B;  3VRR A;  3BI0 A;  2JBJ A;  5D29 A;  3PLF B;  3BUO B;  4X3R A; 
#chains in the Genus database with same CATH homology
 2XPP A;  2XPL A;  3O8Z A;  2N3A B;  2XPN A;  3U88 C;  2XPO A;  1EO0 A;  3OAK A;  1Z9E A;  1WJT A;  3HPH E;  3HPG G;  3NFQ A;  2B4J C;  3F9K C;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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