4RR2B

Crystal structure of human primase
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
224
structure length
213
Chain Sequence
FYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the human primase.
pubmed doi rcsb
molecule keywords DNA primase small subunit
molecule tags Transferase
source organism Homo sapiens
total genus 67
structure length 213
sequence length 224
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2014-11-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF04104 DNA_primase_lrg Eukaryotic and archaeal DNA primase, large subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4rr2B00
4BPWB 4BPXB 4RR2B 4BPUB
chains in the Genus database with same CATH superfamily
3BUXB 4MCQA 4A4CA 4MCSA 4A4BA 3SJEA 3VRRA 2XPOA 3BXMA 5J3XA 4BPWB 2PVVA 2Y1MA 3NFQA 3FEDA 3OB1B 4RR2B 3S9LA 2XPLA 5HKYA 2XEIA 3S9NA 5BY0A 2JBJA 1DE4C 4NGMA 5F09A 3BUOB 2UV8G 3OB2B 3D7DA 4OC1A 3S9MA 3HPGG 5F13A 3VGOA 3F9KC 4BPXB 2C6PA 4GPLB 4P4IA 5ELYA 5AXIA 2XEFA 4JYWA 3SJGA 4BPUB 4MCPA 2VKZG 4OC0A 3U88C 2XEGA 4NGTA 3D7HA 4JZ0A 3BI1A 2XEJA 2OR4A 1WJTA 3VRPA 2OOTA 2PVWA 3VRQA 4NGNA 4P4DA 4LQGA 3FECA 4OC5A 2XPPA 4BTFA 3O8ZA 4OMEA 5D29A 3VRNA 3BI0A 2XPNA 3PLFB 4NGPA 4P4JA 2N3AB 3VROA 1EO0A 4P4FA 3BHXA 1YVHA 4NGRA 4P4BA 3BUMB 2CBLA 4OC2A 4OC3A 3SJXA 4X3RA 2B4JC 3D7GA 3BUWB 4NGQA 5HKZA 3SJFA 2JBKA 1FBVA 3OAKA 3IWWA 3D7FA 2C6GA 5HKWA 1Z8LA 3ZNIA 4W9YA 4P44A 3FF3A 3OP0A 3KASA 2CIJA 2DLAA 1Z9EA 3PFVA 4MCRA 2Y1NA 4P4EA 3PT1A 3HPHE 4NGSA 3FEEA 4P45A 1CX8A 2C6CA 3BUNB 4OC4A 3RBUA 3HMJG 1B47A
chains in the Genus database with same CATH topology
3PT1A 5F13A 4BPWB 2UV8G 4BPUB 5BY0A 2VKZG 2DLAA 4BPXB 3HMJG 4RR2B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPW B;  4BPX B;  4RR2 B;  4BPU B; 
#chains in the Genus database with same CATH topology
 3BUX B;  4MCQ A;  4A4C A;  4MCS A;  4A4B A;  3SJE A;  3VRR A;  2XPO A;  3BXM A;  5J3X A;  4BPW B;  2PVV A;  2Y1M A;  3NFQ A;  3FED A;  3OB1 B;  4RR2 B;  3S9L A;  2XPL A;  5HKY A;  2XEI A;  3S9N A;  5BY0 A;  2JBJ A;  1DE4 C;  4NGM A;  5F09 A;  3BUO B;  2UV8 G;  3OB2 B;  3D7D A;  4OC1 A;  3S9M A;  3HPG G;  5F13 A;  3VGO A;  3F9K C;  4BPX B;  2C6P A;  4GPL B;  4P4I A;  5ELY A;  5AXI A;  2XEF A;  4JYW A;  3SJG A;  4BPU B;  4MCP A;  2VKZ G;  4OC0 A;  3U88 C;  2XEG A;  4NGT A;  3D7H A;  4JZ0 A;  3BI1 A;  2XEJ A;  2OR4 A;  1WJT A;  3VRP A;  2OOT A;  2PVW A;  3VRQ A;  4NGN A;  4P4D A;  4LQG A;  3FEC A;  4OC5 A;  2XPP A;  4BTF A;  3O8Z A;  4OME A;  5D29 A;  3VRN A;  3BI0 A;  2XPN A;  3PLF B;  4NGP A;  4P4J A;  2N3A B;  3VRO A;  1EO0 A;  4P4F A;  3BHX A;  1YVH A;  4NGR A;  4P4B A;  3BUM B;  2CBL A;  4OC2 A;  4OC3 A;  3SJX A;  4X3R A;  2B4J C;  3D7G A;  3BUW B;  4NGQ A;  5HKZ A;  3SJF A;  2JBK A;  1FBV A;  3OAK A;  3IWW A;  3D7F A;  2C6G A;  5HKW A;  1Z8L A;  3ZNI A;  4W9Y A;  4P44 A;  3FF3 A;  3OP0 A;  3KAS A;  2CIJ A;  2DLA A;  1Z9E A;  3PFV A;  4MCR A;  2Y1N A;  4P4E A;  3PT1 A;  3HPH E;  4NGS A;  3FEE A;  4P45 A;  1CX8 A;  2C6C A;  3BUN B;  4OC4 A;  3RBU A;  3HMJ G;  1B47 A; 
#chains in the Genus database with same CATH homology
 3PT1 A;  5F13 A;  4BPW B;  2UV8 G;  4BPU B;  5BY0 A;  2VKZ G;  2DLA A;  4BPX B;  3HMJ G;  4RR2 B; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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