4RR2B

Crystal structure of human primase
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
224
structure length
213
Chain Sequence
FYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords DNA primase small subunit
publication title Crystal structure of the human primase.
pubmed doi rcsb
source organism Homo sapiens
total genus 67
structure length 213
sequence length 224
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2014-11-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF04104 DNA_primase_lrg Eukaryotic and archaeal DNA primase, large subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4rr2B00
4BPXB 4BPUB 4BPWB 4RR2B
chains in the Genus database with same CATH superfamily
3S9LA 5HKWA 4P4IA 3F9KC 1DE4C 2UV8G 4OMEA 3BXMA 2C6PA 2XEFA 2Y1MA 4NGNA 4OC5A 3VRPA 2OOTA 2N3AB 3D7FA 2XPLA 4MCQA 3OB2B 4P4EA 5F09A 3O8ZA 3OB1B 1EO0A 3OP0A 4BPUB 4NGTA 3HPHE 3BHXA 4JYWA 3D7HA 4P4DA 3RBUA 1Z8LA 3BUMB 4MCPA 2C6GA 2CBLA 4BPXB 3PT1A 3VRRA 4BTFA 4A4CA 1Z9EA 4X3RA 3IWWA 3VROA 4A4BA 4RR2B 4W9YA 2DLAA 5ELYA 4P45A 5J3XA 2XEIA 2XEJA 3D7GA 3PFVA 3PLFB 3KASA 4NGQA 3VGOA 4JZ0A 2CIJA 3S9MA 3BI1A 3SJGA 5F13A 2PVVA 4OC3A 1YVHA 2C6CA 4NGMA 2VKZG 4LQGA 2XPOA 3SJEA 3NFQA 3FECA 3OAKA 4P4JA 4GPLB 3BUWB 3D7DA 5AXIA 4MCRA 4P44A 3FEDA 3FEEA 4NGRA 3HPGG 2XPNA 2XPPA 4OC4A 2OR4A 2XEGA 3FF3A 3BI0A 4P4BA 3VRQA 4OC0A 2JBJA 2Y1NA 2JBKA 3SJFA 4OC1A 3ZNIA 1FBVA 1WJTA 5D29A 4BPWB 4NGPA 3HMJG 1CX8A 4MCSA 3BUOB 1B47A 3BUNB 2PVWA 2B4JC 5HKZA 4P4FA 3S9NA 5BY0A 3VRNA 3BUXB 4OC2A 5HKYA 3U88C 4NGSA 3SJXA
chains in the Genus database with same CATH topology
2UV8G 3HMJG 4RR2B 5BY0A 4BPXB 4BPUB 2DLAA 3PT1A 4BPWB 2VKZG 5F13A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPX B;  4BPU B;  4BPW B;  4RR2 B; 
#chains in the Genus database with same CATH topology
 3S9L A;  5HKW A;  4P4I A;  3F9K C;  1DE4 C;  2UV8 G;  4OME A;  3BXM A;  2C6P A;  2XEF A;  2Y1M A;  4NGN A;  4OC5 A;  3VRP A;  2OOT A;  2N3A B;  3D7F A;  2XPL A;  4MCQ A;  3OB2 B;  4P4E A;  5F09 A;  3O8Z A;  3OB1 B;  1EO0 A;  3OP0 A;  4BPU B;  4NGT A;  3HPH E;  3BHX A;  4JYW A;  3D7H A;  4P4D A;  3RBU A;  1Z8L A;  3BUM B;  4MCP A;  2C6G A;  2CBL A;  4BPX B;  3PT1 A;  3VRR A;  4BTF A;  4A4C A;  1Z9E A;  4X3R A;  3IWW A;  3VRO A;  4A4B A;  4RR2 B;  4W9Y A;  2DLA A;  5ELY A;  4P45 A;  5J3X A;  2XEI A;  2XEJ A;  3D7G A;  3PFV A;  3PLF B;  3KAS A;  4NGQ A;  3VGO A;  4JZ0 A;  2CIJ A;  3S9M A;  3BI1 A;  3SJG A;  5F13 A;  2PVV A;  4OC3 A;  1YVH A;  2C6C A;  4NGM A;  2VKZ G;  4LQG A;  2XPO A;  3SJE A;  3NFQ A;  3FEC A;  3OAK A;  4P4J A;  4GPL B;  3BUW B;  3D7D A;  5AXI A;  4MCR A;  4P44 A;  3FED A;  3FEE A;  4NGR A;  3HPG G;  2XPN A;  2XPP A;  4OC4 A;  2OR4 A;  2XEG A;  3FF3 A;  3BI0 A;  4P4B A;  3VRQ A;  4OC0 A;  2JBJ A;  2Y1N A;  2JBK A;  3SJF A;  4OC1 A;  3ZNI A;  1FBV A;  1WJT A;  5D29 A;  4BPW B;  4NGP A;  3HMJ G;  1CX8 A;  4MCS A;  3BUO B;  1B47 A;  3BUN B;  2PVW A;  2B4J C;  5HKZ A;  4P4F A;  3S9N A;  5BY0 A;  3VRN A;  3BUX B;  4OC2 A;  5HKY A;  3U88 C;  4NGS A;  3SJX A; 
#chains in the Genus database with same CATH homology
 2UV8 G;  3HMJ G;  4RR2 B;  5BY0 A;  4BPX B;  4BPU B;  2DLA A;  3PT1 A;  4BPW B;  2VKZ G;  5F13 A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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