4RR2B

Crystal structure of human primase
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
224
structure length
213
Chain Sequence
FYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DNA primase small subunit
publication title Crystal structure of the human primase.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 67
structure length 213
sequence length 224
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2014-11-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF04104 DNA_primase_lrg Eukaryotic and archaeal DNA primase, large subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4rr2B00
4BPXB 4BPWB 4RR2B 4BPUB
chains in the Genus database with same CATH superfamily
2N3AB 4GPLB 4NGMA 2OOTA 3D7DA 2XPPA 4P4IA 4NGTA 2Y1NA 4BTFA 3HMJG 2JBJA 3HPGG 2UV8G 2OR4A 4LQGA 4BPXB 4P4FA 5HKWA 1DE4C 3KASA 2XEFA 4NGRA 3SJXA 4A4BA 4OC2A 1CX8A 4W9YA 2C6GA 4OC1A 4P4BA 3S9MA 1EO0A 4OMEA 5F13A 3VRRA 3FEDA 4BPUB 4NGNA 4OC4A 1Z9EA 3FECA 3F9KC 3OP0A 4A4CA 5HKYA 4P4EA 2C6CA 3BUNB 3VRNA 4JYWA 3VRPA 2XEGA 3PT1A 1YVHA 3SJEA 2XPNA 5D29A 2B4JC 3HPHE 2XEIA 2JBKA 2CBLA 4BPWB 4NGPA 3VROA 4OC0A 3BXMA 3D7GA 3BUOB 4JZ0A 3PFVA 4OC5A 4NGQA 1FBVA 3OB1B 5J3XA 1WJTA 4P4JA 3NFQA 4RR2B 3IWWA 5BY0A 3SJGA 3O8ZA 2Y1MA 4P44A 2XEJA 5HKZA 4MCQA 5ELYA 3BUMB 3VRQA 3S9NA 1Z8LA 3RBUA 5F09A 3ZNIA 2DLAA 3D7HA 4OC3A 4MCPA 2C6PA 5AXIA 4MCRA 4X3RA 3BI1A 1B47A 2XPOA 3BI0A 3SJFA 4NGSA 3OB2B 2VKZG 3U88C 2CIJA 3BUWB 4P4DA 2PVWA 3S9LA 3FEEA 3PLFB 2PVVA 3OAKA 4MCSA 3BUXB 2XPLA 3D7FA 3FF3A 4P45A 3VGOA 3BHXA
chains in the Genus database with same CATH topology
3PT1A 3HMJG 2UV8G 2VKZG 4RR2B 5F13A 4BPXB 5BY0A 2DLAA 4BPWB 4BPUB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPX B;  4BPW B;  4RR2 B;  4BPU B; 
#chains in the Genus database with same CATH topology
 2N3A B;  4GPL B;  4NGM A;  2OOT A;  3D7D A;  2XPP A;  4P4I A;  4NGT A;  2Y1N A;  4BTF A;  3HMJ G;  2JBJ A;  3HPG G;  2UV8 G;  2OR4 A;  4LQG A;  4BPX B;  4P4F A;  5HKW A;  1DE4 C;  3KAS A;  2XEF A;  4NGR A;  3SJX A;  4A4B A;  4OC2 A;  1CX8 A;  4W9Y A;  2C6G A;  4OC1 A;  4P4B A;  3S9M A;  1EO0 A;  4OME A;  5F13 A;  3VRR A;  3FED A;  4BPU B;  4NGN A;  4OC4 A;  1Z9E A;  3FEC A;  3F9K C;  3OP0 A;  4A4C A;  5HKY A;  4P4E A;  2C6C A;  3BUN B;  3VRN A;  4JYW A;  3VRP A;  2XEG A;  3PT1 A;  1YVH A;  3SJE A;  2XPN A;  5D29 A;  2B4J C;  3HPH E;  2XEI A;  2JBK A;  2CBL A;  4BPW B;  4NGP A;  3VRO A;  4OC0 A;  3BXM A;  3D7G A;  3BUO B;  4JZ0 A;  3PFV A;  4OC5 A;  4NGQ A;  1FBV A;  3OB1 B;  5J3X A;  1WJT A;  4P4J A;  3NFQ A;  4RR2 B;  3IWW A;  5BY0 A;  3SJG A;  3O8Z A;  2Y1M A;  4P44 A;  2XEJ A;  5HKZ A;  4MCQ A;  5ELY A;  3BUM B;  3VRQ A;  3S9N A;  1Z8L A;  3RBU A;  5F09 A;  3ZNI A;  2DLA A;  3D7H A;  4OC3 A;  4MCP A;  2C6P A;  5AXI A;  4MCR A;  4X3R A;  3BI1 A;  1B47 A;  2XPO A;  3BI0 A;  3SJF A;  4NGS A;  3OB2 B;  2VKZ G;  3U88 C;  2CIJ A;  3BUW B;  4P4D A;  2PVW A;  3S9L A;  3FEE A;  3PLF B;  2PVV A;  3OAK A;  4MCS A;  3BUX B;  2XPL A;  3D7F A;  3FF3 A;  4P45 A;  3VGO A;  3BHX A; 
#chains in the Genus database with same CATH homology
 3PT1 A;  3HMJ G;  2UV8 G;  2VKZ G;  4RR2 B;  5F13 A;  4BPX B;  5BY0 A;  2DLA A;  4BPW B;  4BPU B; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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