3HPGG

Visna virus integrase (residues 1-219) in complex with ledgf ibd: examples of open integrase dimer-dimer interfaces
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
76
structure length
73
Chain Sequence
MDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for functional tetramerization of lentiviral integrase
pubmed doi rcsb
molecule tags Transferase
source organism Maedi visna virus
molecule keywords Integrase
total genus 16
structure length 73
sequence length 76
chains with identical sequence H, I, J, K, L
ec nomenclature
pdb deposition date 2009-06-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.10 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 3hpgG00
3NFQA 3F9KC 1EO0A 2N3AB 2XPPA 3U88C 3HPHE 3OAKA 2XPLA 1Z9EA 3HPGG 2XPOA 1WJTA 2B4JC 2XPNA 3O8ZA
chains in the Genus database with same CATH superfamily
4OC3A 5HKZA 2XPLA 3BUMB 4NGSA 4MCQA 4RR2B 3VGOA 4OC0A 3BI1A 1B47A 5HKWA 3VROA 4P4JA 1DE4C 4BPWB 1WJTA 3FECA 3FEEA 3D7HA 3VRNA 1EO0A 2JBKA 4OC5A 3BUXB 4BTFA 1Z9EA 4JYWA 3SJXA 4OMEA 3IWWA 4OC4A 3BUOB 3U88C 3D7GA 3KASA 2DLAA 4P4DA 2B4JC 2XEIA 4A4CA 4NGNA 5F13A 5D29A 4MCSA 4P4EA 2PVWA 3BXMA 5ELYA 2XPNA 3ZNIA 3VRQA 3OAKA 4MCPA 3S9LA 3F9KC 3OB1B 4X3RA 1FBVA 2XEJA 4W9YA 3HPHE 3BHXA 3HPGG 3SJEA 2XPOA 3SJFA 4P4BA 5F09A 3D7DA 3NFQA 5BY0A 4OC2A 4LQGA 4P45A 4NGTA 2PVVA 3RBUA 3PT1A 2XEFA 2Y1MA 4NGPA 2C6CA 3PFVA 4NGQA 3HMJG 4GPLB 3VRRA 2C6GA 3BI0A 3BUWB 4NGRA 3S9NA 3O8ZA 3OP0A 4NGMA 2VKZG 4MCRA 5AXIA 4JZ0A 3VRPA 2XPPA 2CBLA 4BPXB 4P44A 4OC1A 1YVHA 3FEDA 2UV8G 3OB2B 2C6PA 3BUNB 3FF3A 3PLFB 1CX8A 4P4IA 2CIJA 5HKYA 2OR4A 5J3XA 2OOTA 2JBJA 4A4BA 4BPUB 3S9MA 4P4FA 3SJGA 2Y1NA 2N3AB 2XEGA 3D7FA 1Z8LA
chains in the Genus database with same CATH topology
3NFQA 3F9KC 1EO0A 2N3AB 2XPPA 3U88C 3HPHE 3OAKA 2XPLA 1Z9EA 3HPGG 2XPOA 1WJTA 2B4JC 2XPNA 3O8ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NFQ A;  3F9K C;  1EO0 A;  2N3A B;  2XPP A;  3U88 C;  3HPH E;  3OAK A;  2XPL A;  1Z9E A;  3HPG G;  2XPO A;  1WJT A;  2B4J C;  2XPN A;  3O8Z A; 
#chains in the Genus database with same CATH topology
 4OC3 A;  5HKZ A;  2XPL A;  3BUM B;  4NGS A;  4MCQ A;  4RR2 B;  3VGO A;  4OC0 A;  3BI1 A;  1B47 A;  5HKW A;  3VRO A;  4P4J A;  1DE4 C;  4BPW B;  1WJT A;  3FEC A;  3FEE A;  3D7H A;  3VRN A;  1EO0 A;  2JBK A;  4OC5 A;  3BUX B;  4BTF A;  1Z9E A;  4JYW A;  3SJX A;  4OME A;  3IWW A;  4OC4 A;  3BUO B;  3U88 C;  3D7G A;  3KAS A;  2DLA A;  4P4D A;  2B4J C;  2XEI A;  4A4C A;  4NGN A;  5F13 A;  5D29 A;  4MCS A;  4P4E A;  2PVW A;  3BXM A;  5ELY A;  2XPN A;  3ZNI A;  3VRQ A;  3OAK A;  4MCP A;  3S9L A;  3F9K C;  3OB1 B;  4X3R A;  1FBV A;  2XEJ A;  4W9Y A;  3HPH E;  3BHX A;  3HPG G;  3SJE A;  2XPO A;  3SJF A;  4P4B A;  5F09 A;  3D7D A;  3NFQ A;  5BY0 A;  4OC2 A;  4LQG A;  4P45 A;  4NGT A;  2PVV A;  3RBU A;  3PT1 A;  2XEF A;  2Y1M A;  4NGP A;  2C6C A;  3PFV A;  4NGQ A;  3HMJ G;  4GPL B;  3VRR A;  2C6G A;  3BI0 A;  3BUW B;  4NGR A;  3S9N A;  3O8Z A;  3OP0 A;  4NGM A;  2VKZ G;  4MCR A;  5AXI A;  4JZ0 A;  3VRP A;  2XPP A;  2CBL A;  4BPX B;  4P44 A;  4OC1 A;  1YVH A;  3FED A;  2UV8 G;  3OB2 B;  2C6P A;  3BUN B;  3FF3 A;  3PLF B;  1CX8 A;  4P4I A;  2CIJ A;  5HKY A;  2OR4 A;  5J3X A;  2OOT A;  2JBJ A;  4A4B A;  4BPU B;  3S9M A;  4P4F A;  3SJG A;  2Y1N A;  2N3A B;  2XEG A;  3D7F A;  1Z8L A; 
#chains in the Genus database with same CATH homology
 3NFQ A;  3F9K C;  1EO0 A;  2N3A B;  2XPP A;  3U88 C;  3HPH E;  3OAK A;  2XPL A;  1Z9E A;  3HPG G;  2XPO A;  1WJT A;  2B4J C;  2XPN A;  3O8Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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