4BPWB

Crystal structure of human primase bound to utp
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
243
structure length
219
Chain Sequence
LRLAGYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSIPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords DNA PRIMASE SMALL SUBUNIT
publication title Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
pubmed doi rcsb
source organism Homo sapiens
total genus 63
structure length 219
sequence length 243
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-05-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4bpwB00
4BPXB 4RR2B 4BPUB 4BPWB
chains in the Genus database with same CATH superfamily
5F09A 5HKYA 1Z9EA 5HKWA 3SJGA 3S9LA 4BPWB 2XEGA 1WJTA 4NGMA 3BI1A 3KASA 3HMJG 4MCRA 3VRNA 4MCSA 3PFVA 4OC1A 3RBUA 2CBLA 2UV8G 3U88C 2OOTA 3BUOB 5AXIA 4P45A 4NGPA 3OP0A 4A4BA 3D7FA 2XPLA 3FEEA 4P4EA 4P4JA 3VRQA 2OR4A 5BY0A 3D7DA 4NGQA 3PLFB 2C6CA 2PVWA 2VKZG 3O8ZA 4NGRA 4OC3A 1CX8A 2N3AB 4OC4A 4X3RA 1YVHA 4NGSA 3IWWA 1FBVA 5J3XA 4JYWA 3OB1B 1DE4C 4NGNA 4P44A 4OC5A 5ELYA 3SJFA 2Y1MA 3OAKA 2C6PA 4OC2A 3VGOA 4P4IA 3VROA 3BUXB 3S9NA 2JBKA 3FEDA 4RR2B 1EO0A 4OMEA 4LQGA 3BXMA 4W9YA 2XEFA 3F9KC 3BUNB 2XEJA 2C6GA 1B47A 3SJXA 2PVVA 2XPPA 4MCPA 3BUWB 3NFQA 2XPOA 3D7HA 4P4FA 3BI0A 2DLAA 2Y1NA 2JBJA 1Z8LA 4BPXB 3SJEA 5D29A 4OC0A 4P4BA 4A4CA 3BUMB 3OB2B 3HPHE 3FECA 2CIJA 3D7GA 3FF3A 4BTFA 2B4JC 4GPLB 3VRRA 4BPUB 3BHXA 4MCQA 4NGTA 3S9MA 4P4DA 2XEIA 5HKZA 2XPNA 3ZNIA 3VRPA 4JZ0A 5F13A 3PT1A 3HPGG
chains in the Genus database with same CATH topology
2VKZG 4RR2B 4BPWB 2UV8G 4BPXB 5BY0A 4BPUB 5F13A 3PT1A 3HMJG 2DLAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPX B;  4RR2 B;  4BPU B;  4BPW B; 
#chains in the Genus database with same CATH topology
 5F09 A;  5HKY A;  1Z9E A;  5HKW A;  3SJG A;  3S9L A;  4BPW B;  2XEG A;  1WJT A;  4NGM A;  3BI1 A;  3KAS A;  3HMJ G;  4MCR A;  3VRN A;  4MCS A;  3PFV A;  4OC1 A;  3RBU A;  2CBL A;  2UV8 G;  3U88 C;  2OOT A;  3BUO B;  5AXI A;  4P45 A;  4NGP A;  3OP0 A;  4A4B A;  3D7F A;  2XPL A;  3FEE A;  4P4E A;  4P4J A;  3VRQ A;  2OR4 A;  5BY0 A;  3D7D A;  4NGQ A;  3PLF B;  2C6C A;  2PVW A;  2VKZ G;  3O8Z A;  4NGR A;  4OC3 A;  1CX8 A;  2N3A B;  4OC4 A;  4X3R A;  1YVH A;  4NGS A;  3IWW A;  1FBV A;  5J3X A;  4JYW A;  3OB1 B;  1DE4 C;  4NGN A;  4P44 A;  4OC5 A;  5ELY A;  3SJF A;  2Y1M A;  3OAK A;  2C6P A;  4OC2 A;  3VGO A;  4P4I A;  3VRO A;  3BUX B;  3S9N A;  2JBK A;  3FED A;  4RR2 B;  1EO0 A;  4OME A;  4LQG A;  3BXM A;  4W9Y A;  2XEF A;  3F9K C;  3BUN B;  2XEJ A;  2C6G A;  1B47 A;  3SJX A;  2PVV A;  2XPP A;  4MCP A;  3BUW B;  3NFQ A;  2XPO A;  3D7H A;  4P4F A;  3BI0 A;  2DLA A;  2Y1N A;  2JBJ A;  1Z8L A;  4BPX B;  3SJE A;  5D29 A;  4OC0 A;  4P4B A;  4A4C A;  3BUM B;  3OB2 B;  3HPH E;  3FEC A;  2CIJ A;  3D7G A;  3FF3 A;  4BTF A;  2B4J C;  4GPL B;  3VRR A;  4BPU B;  3BHX A;  4MCQ A;  4NGT A;  3S9M A;  4P4D A;  2XEI A;  5HKZ A;  2XPN A;  3ZNI A;  3VRP A;  4JZ0 A;  5F13 A;  3PT1 A;  3HPG G; 
#chains in the Genus database with same CATH homology
 2VKZ G;  4RR2 B;  4BPW B;  2UV8 G;  4BPX B;  5BY0 A;  4BPU B;  5F13 A;  3PT1 A;  3HMJ G;  2DLA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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