4BPWB

Crystal structure of human primase bound to utp
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
243
structure length
219
Chain Sequence
LRLAGYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSIPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords DNA PRIMASE SMALL SUBUNIT
total genus 63
structure length 219
sequence length 243
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-05-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4bpwB00
4BPXB 4BPWB 4BPUB 4RR2B
chains in the Genus database with same CATH superfamily
3OP0A 3VGOA 2VKZG 1YVHA 1B47A 3BUXB 1WJTA 3NFQA 2OR4A 2XPPA 4P4JA 3BUNB 2CBLA 4BPUB 1FBVA 3S9MA 2XPNA 2XPLA 3HPGG 4P4FA 4MCRA 3OB2B 5D29A 3FECA 4BPWB 1EO0A 2UV8G 3SJFA 3S9NA 3PLFB 3KASA 4W9YA 5AXIA 3BI1A 3PT1A 2PVWA 3FF3A 4P4IA 4A4CA 4JZ0A 2Y1MA 2JBKA 2PVVA 3RBUA 5F13A 3PFVA 3ZNIA 4P4EA 4NGPA 4OC0A 4A4BA 3VRRA 2JBJA 3D7FA 2XEIA 3IWWA 2Y1NA 4NGMA 2C6PA 3D7HA 2XEJA 4BPXB 3U88C 3OAKA 3OB1B 3D7DA 3S9LA 2XEFA 2N3AB 3O8ZA 3BUMB 3SJXA 4MCQA 4LQGA 1DE4C 4OC4A 3FEEA 4OC2A 4NGTA 3VRPA 4P44A 4RR2B 5J3XA 4MCPA 3SJGA 1Z9EA 3D7GA 1Z8LA 2OOTA 3VRQA 3SJEA 4NGQA 4NGSA 2DLAA 3FEDA 3BXMA 1CX8A 4NGRA 5HKYA 4X3RA 4P4BA 3BHXA 4BTFA 5HKWA 3F9KC 2C6GA 4OC1A 4P45A 2CIJA 4NGNA 4OMEA 2B4JC 3BUWB 4OC3A 5F09A 3HMJG 5BY0A 2XEGA 2C6CA 3BUOB 3VROA 3HPHE 4JYWA 4OC5A 4P4DA 4MCSA 3VRNA 5HKZA 3BI0A 5ELYA 2XPOA 4GPLB
chains in the Genus database with same CATH topology
3PT1A 2DLAA 4BPXB 4BPWB 2UV8G 4RR2B 2VKZG 5F13A 4BPUB 3HMJG 5BY0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPX B;  4BPW B;  4BPU B;  4RR2 B; 
#chains in the Genus database with same CATH topology
 3OP0 A;  3VGO A;  2VKZ G;  1YVH A;  1B47 A;  3BUX B;  1WJT A;  3NFQ A;  2OR4 A;  2XPP A;  4P4J A;  3BUN B;  2CBL A;  4BPU B;  1FBV A;  3S9M A;  2XPN A;  2XPL A;  3HPG G;  4P4F A;  4MCR A;  3OB2 B;  5D29 A;  3FEC A;  4BPW B;  1EO0 A;  2UV8 G;  3SJF A;  3S9N A;  3PLF B;  3KAS A;  4W9Y A;  5AXI A;  3BI1 A;  3PT1 A;  2PVW A;  3FF3 A;  4P4I A;  4A4C A;  4JZ0 A;  2Y1M A;  2JBK A;  2PVV A;  3RBU A;  5F13 A;  3PFV A;  3ZNI A;  4P4E A;  4NGP A;  4OC0 A;  4A4B A;  3VRR A;  2JBJ A;  3D7F A;  2XEI A;  3IWW A;  2Y1N A;  4NGM A;  2C6P A;  3D7H A;  2XEJ A;  4BPX B;  3U88 C;  3OAK A;  3OB1 B;  3D7D A;  3S9L A;  2XEF A;  2N3A B;  3O8Z A;  3BUM B;  3SJX A;  4MCQ A;  4LQG A;  1DE4 C;  4OC4 A;  3FEE A;  4OC2 A;  4NGT A;  3VRP A;  4P44 A;  4RR2 B;  5J3X A;  4MCP A;  3SJG A;  1Z9E A;  3D7G A;  1Z8L A;  2OOT A;  3VRQ A;  3SJE A;  4NGQ A;  4NGS A;  2DLA A;  3FED A;  3BXM A;  1CX8 A;  4NGR A;  5HKY A;  4X3R A;  4P4B A;  3BHX A;  4BTF A;  5HKW A;  3F9K C;  2C6G A;  4OC1 A;  4P45 A;  2CIJ A;  4NGN A;  4OME A;  2B4J C;  3BUW B;  4OC3 A;  5F09 A;  3HMJ G;  5BY0 A;  2XEG A;  2C6C A;  3BUO B;  3VRO A;  3HPH E;  4JYW A;  4OC5 A;  4P4D A;  4MCS A;  3VRN A;  5HKZ A;  3BI0 A;  5ELY A;  2XPO A;  4GPL B; 
#chains in the Genus database with same CATH homology
 3PT1 A;  2DLA A;  4BPX B;  4BPW B;  2UV8 G;  4RR2 B;  2VKZ G;  5F13 A;  4BPU B;  3HMJ G;  5BY0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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