4BPWB

Crystal structure of human primase bound to utp
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
243
structure length
219
Chain Sequence
LRLAGYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSIPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
pubmed doi rcsb
molecule keywords DNA PRIMASE SMALL SUBUNIT
molecule tags Transferase
source organism Homo sapiens
total genus 63
structure length 219
sequence length 243
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-05-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4bpwB00
4BPXB 4RR2B 4BPWB 4BPUB
chains in the Genus database with same CATH superfamily
4BPXB 3FF3A 3RBUA 5F13A 3SJFA 3S9LA 4NGQA 3BI1A 2JBKA 2DLAA 4A4BA 4NGMA 1EO0A 5ELYA 5J3XA 3S9NA 5BY0A 4P4IA 3BUNB 4OC1A 2CIJA 2XEGA 1DE4C 3OB1B 3VRQA 4JZ0A 2UV8G 4OMEA 4OC4A 1B47A 4P45A 4P4EA 2C6CA 3BUMB 4LQGA 3D7DA 3OB2B 4RR2B 4OC3A 3IWWA 2XPLA 3KASA 5HKZA 2Y1NA 4NGSA 1CX8A 3SJEA 3SJGA 2CBLA 4OC2A 2VKZG 2OR4A 5D29A 4GPLB 5HKWA 3VRRA 3PLFB 4P4DA 3NFQA 3OP0A 4P4BA 4JYWA 4W9YA 4NGNA 3FEEA 2C6PA 2OOTA 4P4FA 2XEFA 2XPNA 3HPHE 3FECA 2XPPA 3BXMA 3HPGG 4BPWB 2B4JC 2PVVA 4OC5A 4A4CA 4NGTA 4OC0A 3BUWB 3D7GA 3PT1A 2C6GA 3VRPA 2N3AB 1YVHA 3S9MA 1WJTA 2XPOA 4P44A 3FEDA 3F9KC 2PVWA 4MCRA 4P4JA 3O8ZA 3BUOB 2XEJA 3HMJG 3D7HA 2Y1MA 4MCQA 4BTFA 1Z9EA 3OAKA 5AXIA 3VRNA 3PFVA 4NGPA 1Z8LA 3D7FA 3VGOA 3SJXA 3U88C 3ZNIA 3BI0A 4BPUB 3BUXB 5F09A 3BHXA 2JBJA 2XEIA 4X3RA 3VROA 4MCPA 1FBVA 5HKYA 4MCSA 4NGRA
chains in the Genus database with same CATH topology
4BPXB 2VKZG 4BPWB 3HMJG 2UV8G 3PT1A 5F13A 4RR2B 4BPUB 5BY0A 2DLAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPX B;  4RR2 B;  4BPW B;  4BPU B; 
#chains in the Genus database with same CATH topology
 4BPX B;  3FF3 A;  3RBU A;  5F13 A;  3SJF A;  3S9L A;  4NGQ A;  3BI1 A;  2JBK A;  2DLA A;  4A4B A;  4NGM A;  1EO0 A;  5ELY A;  5J3X A;  3S9N A;  5BY0 A;  4P4I A;  3BUN B;  4OC1 A;  2CIJ A;  2XEG A;  1DE4 C;  3OB1 B;  3VRQ A;  4JZ0 A;  2UV8 G;  4OME A;  4OC4 A;  1B47 A;  4P45 A;  4P4E A;  2C6C A;  3BUM B;  4LQG A;  3D7D A;  3OB2 B;  4RR2 B;  4OC3 A;  3IWW A;  2XPL A;  3KAS A;  5HKZ A;  2Y1N A;  4NGS A;  1CX8 A;  3SJE A;  3SJG A;  2CBL A;  4OC2 A;  2VKZ G;  2OR4 A;  5D29 A;  4GPL B;  5HKW A;  3VRR A;  3PLF B;  4P4D A;  3NFQ A;  3OP0 A;  4P4B A;  4JYW A;  4W9Y A;  4NGN A;  3FEE A;  2C6P A;  2OOT A;  4P4F A;  2XEF A;  2XPN A;  3HPH E;  3FEC A;  2XPP A;  3BXM A;  3HPG G;  4BPW B;  2B4J C;  2PVV A;  4OC5 A;  4A4C A;  4NGT A;  4OC0 A;  3BUW B;  3D7G A;  3PT1 A;  2C6G A;  3VRP A;  2N3A B;  1YVH A;  3S9M A;  1WJT A;  2XPO A;  4P44 A;  3FED A;  3F9K C;  2PVW A;  4MCR A;  4P4J A;  3O8Z A;  3BUO B;  2XEJ A;  3HMJ G;  3D7H A;  2Y1M A;  4MCQ A;  4BTF A;  1Z9E A;  3OAK A;  5AXI A;  3VRN A;  3PFV A;  4NGP A;  1Z8L A;  3D7F A;  3VGO A;  3SJX A;  3U88 C;  3ZNI A;  3BI0 A;  4BPU B;  3BUX B;  5F09 A;  3BHX A;  2JBJ A;  2XEI A;  4X3R A;  3VRO A;  4MCP A;  1FBV A;  5HKY A;  4MCS A;  4NGR A; 
#chains in the Genus database with same CATH homology
 4BPX B;  2VKZ G;  4BPW B;  3HMJ G;  2UV8 G;  3PT1 A;  5F13 A;  4RR2 B;  4BPU B;  5BY0 A;  2DLA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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