4BPWB

Crystal structure of human primase bound to utp
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
243
structure length
219
Chain Sequence
LRLAGYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSIPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DNA PRIMASE SMALL SUBUNIT
publication title Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 63
structure length 219
sequence length 243
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-05-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4bpwB00
4BPUB 4BPXB 4RR2B 4BPWB
chains in the Genus database with same CATH superfamily
3F9KC 3HMJG 4NGTA 3FEDA 4P44A 4BTFA 2XPPA 4P4FA 2PVVA 2B4JC 4A4BA 2Y1MA 5F13A 3RBUA 4NGPA 2C6PA 3S9MA 1FBVA 3BUMB 3KASA 4BPUB 5F09A 2XEIA 2XPOA 5ELYA 5HKZA 4NGMA 3OB2B 3PLFB 3NFQA 3VGOA 1YVHA 4GPLB 2Y1NA 3SJEA 3BUOB 5HKWA 3VRRA 1Z9EA 2XPLA 4NGRA 2OOTA 4MCPA 3BI1A 4MCRA 3PFVA 4OC1A 2PVWA 3D7GA 3FEEA 4A4CA 2C6CA 3PT1A 4OC4A 3SJXA 4P4BA 3SJGA 3VRQA 5BY0A 4OC0A 2XEGA 4MCSA 3HPHE 2C6GA 4BPXB 4W9YA 3OP0A 5D29A 1B47A 2JBKA 4P4IA 4NGSA 2JBJA 4OMEA 3O8ZA 3HPGG 2OR4A 4JYWA 4RR2B 2N3AB 1EO0A 4P4JA 3D7FA 3IWWA 3OB1B 5HKYA 1Z8LA 2UV8G 4NGNA 4BPWB 3FF3A 3BHXA 1WJTA 4JZ0A 3OAKA 4MCQA 3S9NA 2CIJA 2CBLA 3D7DA 3SJFA 1DE4C 3VRNA 4OC5A 3VROA 1CX8A 3ZNIA 2DLAA 4P4EA 3BUXB 3U88C 3VRPA 2XEFA 3BUNB 4P45A 5AXIA 4OC3A 2XEJA 4NGQA 2VKZG 4P4DA 3BXMA 3BUWB 5J3XA 3FECA 3S9LA 4X3RA 4LQGA 4OC2A 2XPNA 3D7HA 3BI0A
chains in the Genus database with same CATH topology
3HMJG 3PT1A 2UV8G 2VKZG 4BPWB 4BPXB 5BY0A 2DLAA 4BPUB 4RR2B 5F13A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPU B;  4BPX B;  4RR2 B;  4BPW B; 
#chains in the Genus database with same CATH topology
 3F9K C;  3HMJ G;  4NGT A;  3FED A;  4P44 A;  4BTF A;  2XPP A;  4P4F A;  2PVV A;  2B4J C;  4A4B A;  2Y1M A;  5F13 A;  3RBU A;  4NGP A;  2C6P A;  3S9M A;  1FBV A;  3BUM B;  3KAS A;  4BPU B;  5F09 A;  2XEI A;  2XPO A;  5ELY A;  5HKZ A;  4NGM A;  3OB2 B;  3PLF B;  3NFQ A;  3VGO A;  1YVH A;  4GPL B;  2Y1N A;  3SJE A;  3BUO B;  5HKW A;  3VRR A;  1Z9E A;  2XPL A;  4NGR A;  2OOT A;  4MCP A;  3BI1 A;  4MCR A;  3PFV A;  4OC1 A;  2PVW A;  3D7G A;  3FEE A;  4A4C A;  2C6C A;  3PT1 A;  4OC4 A;  3SJX A;  4P4B A;  3SJG A;  3VRQ A;  5BY0 A;  4OC0 A;  2XEG A;  4MCS A;  3HPH E;  2C6G A;  4BPX B;  4W9Y A;  3OP0 A;  5D29 A;  1B47 A;  2JBK A;  4P4I A;  4NGS A;  2JBJ A;  4OME A;  3O8Z A;  3HPG G;  2OR4 A;  4JYW A;  4RR2 B;  2N3A B;  1EO0 A;  4P4J A;  3D7F A;  3IWW A;  3OB1 B;  5HKY A;  1Z8L A;  2UV8 G;  4NGN A;  4BPW B;  3FF3 A;  3BHX A;  1WJT A;  4JZ0 A;  3OAK A;  4MCQ A;  3S9N A;  2CIJ A;  2CBL A;  3D7D A;  3SJF A;  1DE4 C;  3VRN A;  4OC5 A;  3VRO A;  1CX8 A;  3ZNI A;  2DLA A;  4P4E A;  3BUX B;  3U88 C;  3VRP A;  2XEF A;  3BUN B;  4P45 A;  5AXI A;  4OC3 A;  2XEJ A;  4NGQ A;  2VKZ G;  4P4D A;  3BXM A;  3BUW B;  5J3X A;  3FEC A;  3S9L A;  4X3R A;  4LQG A;  4OC2 A;  2XPN A;  3D7H A;  3BI0 A; 
#chains in the Genus database with same CATH homology
 3HMJ G;  3PT1 A;  2UV8 G;  2VKZ G;  4BPW B;  4BPX B;  5BY0 A;  2DLA A;  4BPU B;  4RR2 B;  5F13 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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