4BPUB

Crystal structure of human primase in heterodimeric form, comprising pris and truncated pril lacking the c-terminal fe-s domain.
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
244
structure length
216
Chain Sequence
KLRLAGYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords DNA PRIMASE SMALL SUBUNIT
publication title Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
pubmed doi rcsb
source organism Homo sapiens
total genus 70
structure length 216
sequence length 244
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-05-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4bpuB00
4BPWB 4BPUB 4RR2B 4BPXB
chains in the Genus database with same CATH superfamily
3IWWA 5HKZA 4JYWA 3VRNA 3BUWB 4NGPA 4P4BA 2XEGA 2DLAA 1CX8A 3VRRA 3O8ZA 3ZNIA 4NGNA 3BUNB 3U88C 4OC3A 2XPLA 3SJXA 2OOTA 4P4DA 1B47A 3BI0A 4X3RA 4LQGA 2JBJA 3BI1A 3VGOA 4OC5A 5F13A 4OC2A 3PLFB 4W9YA 4P4EA 5BY0A 1FBVA 5AXIA 4P4IA 3BHXA 5J3XA 5HKYA 3S9NA 3FECA 2VKZG 4MCSA 2XEFA 3D7HA 3HMJG 4NGTA 2C6PA 3VRPA 2Y1MA 4OC1A 3OB1B 2CBLA 3BXMA 2JBKA 1Z9EA 3SJEA 3OAKA 2PVWA 5F09A 3SJGA 3FEEA 3D7GA 4MCRA 3HPGG 4A4BA 1Z8LA 2CIJA 2XPNA 4P4FA 2UV8G 4BTFA 3OB2B 4OC4A 4NGRA 3FF3A 4BPXB 1YVHA 1WJTA 5HKWA 3VROA 4MCPA 1DE4C 2B4JC 3SJFA 4NGQA 3OP0A 3HPHE 4A4CA 2XPOA 2PVVA 4RR2B 4OC0A 3PFVA 2XEIA 4BPUB 4NGSA 2XEJA 4JZ0A 3RBUA 4P44A 2OR4A 3KASA 1EO0A 3NFQA 4MCQA 2N3AB 3S9LA 3F9KC 3D7FA 4GPLB 5ELYA 3FEDA 3S9MA 4P4JA 3VRQA 2C6CA 4NGMA 2C6GA 4P45A 3BUOB 3D7DA 3BUMB 2XPPA 4OMEA 4BPWB 3PT1A 3BUXB 2Y1NA 5D29A
chains in the Genus database with same CATH topology
5F13A 4RR2B 2VKZG 2UV8G 4BPWB 3HMJG 3PT1A 4BPUB 2DLAA 5BY0A 4BPXB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPW B;  4BPU B;  4RR2 B;  4BPX B; 
#chains in the Genus database with same CATH topology
 3IWW A;  5HKZ A;  4JYW A;  3VRN A;  3BUW B;  4NGP A;  4P4B A;  2XEG A;  2DLA A;  1CX8 A;  3VRR A;  3O8Z A;  3ZNI A;  4NGN A;  3BUN B;  3U88 C;  4OC3 A;  2XPL A;  3SJX A;  2OOT A;  4P4D A;  1B47 A;  3BI0 A;  4X3R A;  4LQG A;  2JBJ A;  3BI1 A;  3VGO A;  4OC5 A;  5F13 A;  4OC2 A;  3PLF B;  4W9Y A;  4P4E A;  5BY0 A;  1FBV A;  5AXI A;  4P4I A;  3BHX A;  5J3X A;  5HKY A;  3S9N A;  3FEC A;  2VKZ G;  4MCS A;  2XEF A;  3D7H A;  3HMJ G;  4NGT A;  2C6P A;  3VRP A;  2Y1M A;  4OC1 A;  3OB1 B;  2CBL A;  3BXM A;  2JBK A;  1Z9E A;  3SJE A;  3OAK A;  2PVW A;  5F09 A;  3SJG A;  3FEE A;  3D7G A;  4MCR A;  3HPG G;  4A4B A;  1Z8L A;  2CIJ A;  2XPN A;  4P4F A;  2UV8 G;  4BTF A;  3OB2 B;  4OC4 A;  4NGR A;  3FF3 A;  4BPX B;  1YVH A;  1WJT A;  5HKW A;  3VRO A;  4MCP A;  1DE4 C;  2B4J C;  3SJF A;  4NGQ A;  3OP0 A;  3HPH E;  4A4C A;  2XPO A;  2PVV A;  4RR2 B;  4OC0 A;  3PFV A;  2XEI A;  4BPU B;  4NGS A;  2XEJ A;  4JZ0 A;  3RBU A;  4P44 A;  2OR4 A;  3KAS A;  1EO0 A;  3NFQ A;  4MCQ A;  2N3A B;  3S9L A;  3F9K C;  3D7F A;  4GPL B;  5ELY A;  3FED A;  3S9M A;  4P4J A;  3VRQ A;  2C6C A;  4NGM A;  2C6G A;  4P45 A;  3BUO B;  3D7D A;  3BUM B;  2XPP A;  4OME A;  4BPW B;  3PT1 A;  3BUX B;  2Y1N A;  5D29 A; 
#chains in the Genus database with same CATH homology
 5F13 A;  4RR2 B;  2VKZ G;  2UV8 G;  4BPW B;  3HMJ G;  3PT1 A;  4BPU B;  2DLA A;  5BY0 A;  4BPX B; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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