4BPUB

Crystal structure of human primase in heterodimeric form, comprising pris and truncated pril lacking the c-terminal fe-s domain.
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
244
structure length
216
Chain Sequence
KLRLAGYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DNA PRIMASE SMALL SUBUNIT
publication title Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 70
structure length 216
sequence length 244
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-05-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4bpuB00
4RR2B 4BPWB 4BPXB 4BPUB
chains in the Genus database with same CATH superfamily
3HMJG 1YVHA 3SJFA 4OC2A 1FBVA 2XPNA 3S9MA 3BI1A 4P4BA 2JBKA 3VRPA 3RBUA 3VGOA 4A4BA 4NGTA 3D7GA 5HKYA 4P4FA 1WJTA 3BUMB 5J3XA 1B47A 3VROA 3NFQA 3D7FA 3BUWB 5D29A 3PLFB 4X3RA 5F13A 2OR4A 3IWWA 2XEIA 3FEEA 3KASA 2UV8G 3U88C 2OOTA 2CBLA 2N3AB 4LQGA 5F09A 3BXMA 3S9NA 5BY0A 4BPUB 4BPXB 4MCSA 4P44A 3VRQA 3HPGG 2XEFA 5ELYA 3SJXA 1CX8A 4OC4A 5AXIA 4A4CA 4P45A 4BPWB 2C6PA 4GPLB 3OB2B 4MCPA 3BI0A 4W9YA 1DE4C 4OC5A 2PVWA 2JBJA 2C6GA 4OC3A 1EO0A 4JZ0A 3D7HA 2XPOA 3VRNA 3OP0A 3BUXB 4P4JA 2DLAA 4NGSA 4NGQA 3ZNIA 4NGMA 2C6CA 3SJGA 3FF3A 3OAKA 4OC0A 4P4DA 3BUOB 4MCRA 4JYWA 4NGNA 4P4EA 2Y1NA 4BTFA 3F9KC 4NGRA 4P4IA 3S9LA 2XEJA 3FECA 2PVVA 5HKZA 3FEDA 3OB1B 2CIJA 4OMEA 5HKWA 4MCQA 3O8ZA 2B4JC 3BHXA 2XPLA 2XEGA 3PFVA 1Z9EA 1Z8LA 2XPPA 2Y1MA 4OC1A 2VKZG 3VRRA 3BUNB 4RR2B 3D7DA 4NGPA 3SJEA 3HPHE 3PT1A
chains in the Genus database with same CATH topology
3HMJG 4BPWB 5F13A 4BPXB 2DLAA 2VKZG 4RR2B 2UV8G 3PT1A 5BY0A 4BPUB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RR2 B;  4BPW B;  4BPX B;  4BPU B; 
#chains in the Genus database with same CATH topology
 3HMJ G;  1YVH A;  3SJF A;  4OC2 A;  1FBV A;  2XPN A;  3S9M A;  3BI1 A;  4P4B A;  2JBK A;  3VRP A;  3RBU A;  3VGO A;  4A4B A;  4NGT A;  3D7G A;  5HKY A;  4P4F A;  1WJT A;  3BUM B;  5J3X A;  1B47 A;  3VRO A;  3NFQ A;  3D7F A;  3BUW B;  5D29 A;  3PLF B;  4X3R A;  5F13 A;  2OR4 A;  3IWW A;  2XEI A;  3FEE A;  3KAS A;  2UV8 G;  3U88 C;  2OOT A;  2CBL A;  2N3A B;  4LQG A;  5F09 A;  3BXM A;  3S9N A;  5BY0 A;  4BPU B;  4BPX B;  4MCS A;  4P44 A;  3VRQ A;  3HPG G;  2XEF A;  5ELY A;  3SJX A;  1CX8 A;  4OC4 A;  5AXI A;  4A4C A;  4P45 A;  4BPW B;  2C6P A;  4GPL B;  3OB2 B;  4MCP A;  3BI0 A;  4W9Y A;  1DE4 C;  4OC5 A;  2PVW A;  2JBJ A;  2C6G A;  4OC3 A;  1EO0 A;  4JZ0 A;  3D7H A;  2XPO A;  3VRN A;  3OP0 A;  3BUX B;  4P4J A;  2DLA A;  4NGS A;  4NGQ A;  3ZNI A;  4NGM A;  2C6C A;  3SJG A;  3FF3 A;  3OAK A;  4OC0 A;  4P4D A;  3BUO B;  4MCR A;  4JYW A;  4NGN A;  4P4E A;  2Y1N A;  4BTF A;  3F9K C;  4NGR A;  4P4I A;  3S9L A;  2XEJ A;  3FEC A;  2PVV A;  5HKZ A;  3FED A;  3OB1 B;  2CIJ A;  4OME A;  5HKW A;  4MCQ A;  3O8Z A;  2B4J C;  3BHX A;  2XPL A;  2XEG A;  3PFV A;  1Z9E A;  1Z8L A;  2XPP A;  2Y1M A;  4OC1 A;  2VKZ G;  3VRR A;  3BUN B;  4RR2 B;  3D7D A;  4NGP A;  3SJE A;  3HPH E;  3PT1 A; 
#chains in the Genus database with same CATH homology
 3HMJ G;  4BPW B;  5F13 A;  4BPX B;  2DLA A;  2VKZ G;  4RR2 B;  2UV8 G;  3PT1 A;  5BY0 A;  4BPU B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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