4BPUB

Crystal structure of human primase in heterodimeric form, comprising pris and truncated pril lacking the c-terminal fe-s domain.
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
244
structure length
216
Chain Sequence
b'KLRLAGYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DNA PRIMASE SMALL SUBUNIT
publication title Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 70
structure length 216
sequence length 244
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-05-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4bpuB00
4BPWB 4RR2B 4BPXB 4BPUB
chains in the Genus database with same CATH superfamily
3FEDA 3IWWA 4JYWA 2XEFA 3PFVA 4BPUB 2XPLA 4MCSA 3BI1A 3VRPA 4OC4A 3VROA 2XEJA 4X3RA 1Z9EA 3HPHE 3S9NA 5J3XA 3FEEA 2Y1NA 4P4DA 2B4JC 2N3AB 3U88C 4BPXB 2PVVA 4NGSA 2XEGA 2DLAA 4OC0A 3BI0A 3F9KC 4A4CA 3VGOA 3O8ZA 1B47A 4NGMA 4P4IA 3KASA 3BXMA 3PT1A 3BUXB 3BUMB 5HKZA 3D7HA 3OB2B 4P4FA 5HKWA 3S9MA 2UV8G 5BY0A 3D7DA 4OC3A 2OR4A 4MCQA 3OAKA 4A4BA 3D7GA 4GPLB 3S9LA 3VRNA 4BPWB 1CX8A 4NGTA 4NGRA 2CBLA 4MCRA 3FF3A 4W9YA 2C6PA 3BUWB 2JBJA 3SJGA 3PLFB 3D7FA 3VRQA 3VRRA 3BUOB 3BHXA 5F09A 4MCPA 1EO0A 4NGQA 1WJTA 2XPOA 4OC2A 3SJEA 2XPNA 3BUNB 4OMEA 3ZNIA 4P4EA 2XPPA 3OP0A 2CIJA 3SJXA 1Z8LA 3NFQA 4RR2B 4P45A 4NGPA 2PVWA 5F13A 3SJFA 2JBKA 4OC5A 3HPGG 2Y1MA 1FBVA 4P44A 4BTFA 2C6GA 5D29A 5HKYA 4NGNA 1DE4C 4LQGA 5ELYA 3OB1B 4P4JA 2OOTA 4P4BA 2XEIA 2VKZG 2C6CA 4OC1A 3HMJG 4JZ0A 1YVHA 3RBUA 3FECA 5AXIA
chains in the Genus database with same CATH topology
4BPWB 3PT1A 2VKZG 2DLAA 3HMJG 5F13A 4RR2B 2UV8G 4BPUB 5BY0A 4BPXB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPW B;  4RR2 B;  4BPX B;  4BPU B; 
#chains in the Genus database with same CATH topology
 3FED A;  3IWW A;  4JYW A;  2XEF A;  3PFV A;  4BPU B;  2XPL A;  4MCS A;  3BI1 A;  3VRP A;  4OC4 A;  3VRO A;  2XEJ A;  4X3R A;  1Z9E A;  3HPH E;  3S9N A;  5J3X A;  3FEE A;  2Y1N A;  4P4D A;  2B4J C;  2N3A B;  3U88 C;  4BPX B;  2PVV A;  4NGS A;  2XEG A;  2DLA A;  4OC0 A;  3BI0 A;  3F9K C;  4A4C A;  3VGO A;  3O8Z A;  1B47 A;  4NGM A;  4P4I A;  3KAS A;  3BXM A;  3PT1 A;  3BUX B;  3BUM B;  5HKZ A;  3D7H A;  3OB2 B;  4P4F A;  5HKW A;  3S9M A;  2UV8 G;  5BY0 A;  3D7D A;  4OC3 A;  2OR4 A;  4MCQ A;  3OAK A;  4A4B A;  3D7G A;  4GPL B;  3S9L A;  3VRN A;  4BPW B;  1CX8 A;  4NGT A;  4NGR A;  2CBL A;  4MCR A;  3FF3 A;  4W9Y A;  2C6P A;  3BUW B;  2JBJ A;  3SJG A;  3PLF B;  3D7F A;  3VRQ A;  3VRR A;  3BUO B;  3BHX A;  5F09 A;  4MCP A;  1EO0 A;  4NGQ A;  1WJT A;  2XPO A;  4OC2 A;  3SJE A;  2XPN A;  3BUN B;  4OME A;  3ZNI A;  4P4E A;  2XPP A;  3OP0 A;  2CIJ A;  3SJX A;  1Z8L A;  3NFQ A;  4RR2 B;  4P45 A;  4NGP A;  2PVW A;  5F13 A;  3SJF A;  2JBK A;  4OC5 A;  3HPG G;  2Y1M A;  1FBV A;  4P44 A;  4BTF A;  2C6G A;  5D29 A;  5HKY A;  4NGN A;  1DE4 C;  4LQG A;  5ELY A;  3OB1 B;  4P4J A;  2OOT A;  4P4B A;  2XEI A;  2VKZ G;  2C6C A;  4OC1 A;  3HMJ G;  4JZ0 A;  1YVH A;  3RBU A;  3FEC A;  5AXI A; 
#chains in the Genus database with same CATH homology
 4BPW B;  3PT1 A;  2VKZ G;  2DLA A;  3HMJ G;  5F13 A;  4RR2 B;  2UV8 G;  4BPU B;  5BY0 A;  4BPX B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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