4BPUB

Crystal structure of human primase in heterodimeric form, comprising pris and truncated pril lacking the c-terminal fe-s domain.
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
244
structure length
216
Chain Sequence
KLRLAGYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
pubmed doi rcsb
molecule keywords DNA PRIMASE SMALL SUBUNIT
molecule tags Transferase
source organism Homo sapiens
total genus 70
structure length 216
sequence length 244
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-05-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4bpuB00
4BPUB 4BPWB 4BPXB 4RR2B
chains in the Genus database with same CATH superfamily
2C6CA 3BHXA 5F13A 4MCQA 3S9LA 3BUMB 4OC0A 4P4DA 1Z9EA 3VRNA 2UV8G 2XPOA 2JBJA 4OC1A 2Y1MA 3IWWA 4OC3A 3BXMA 3FEDA 4NGMA 5HKYA 3BI0A 3FF3A 3VGOA 4MCPA 4P4JA 3PLFB 3BUNB 4P4IA 2PVVA 3SJGA 2XEGA 3FECA 2CBLA 3OAKA 4BPWB 3D7GA 3HMJG 4NGPA 4P4EA 3PFVA 5BY0A 1EO0A 4A4BA 4P44A 5AXIA 4P45A 5ELYA 4GPLB 4A4CA 3BUXB 2OR4A 4LQGA 5HKZA 3SJFA 3BI1A 3VRRA 2XPLA 1CX8A 1WJTA 4JYWA 1YVHA 2C6GA 2OOTA 5D29A 2XEIA 3D7DA 4NGSA 3D7HA 2B4JC 3OB1B 3PT1A 2DLAA 1Z8LA 2JBKA 1B47A 4P4FA 1FBVA 4RR2B 3OB2B 3BUWB 3HPHE 2C6PA 3VROA 3BUOB 2XEJA 5HKWA 3VRPA 4NGTA 4OC2A 3HPGG 3FEEA 3RBUA 3S9MA 4P4BA 2CIJA 4NGNA 4BPXB 3SJEA 3SJXA 4NGQA 3S9NA 3NFQA 4OC5A 3ZNIA 4OC4A 4X3RA 2XPNA 2PVWA 4JZ0A 3U88C 3VRQA 4NGRA 3OP0A 4OMEA 2N3AB 2XEFA 2Y1NA 2VKZG 4BPUB 4BTFA 3KASA 4MCRA 5J3XA 3F9KC 1DE4C 2XPPA 4MCSA 5F09A 3D7FA 3O8ZA 4W9YA
chains in the Genus database with same CATH topology
2VKZG 3PT1A 4RR2B 4BPXB 4BPUB 2DLAA 5BY0A 5F13A 3HMJG 2UV8G 4BPWB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPU B;  4BPW B;  4BPX B;  4RR2 B; 
#chains in the Genus database with same CATH topology
 2C6C A;  3BHX A;  5F13 A;  4MCQ A;  3S9L A;  3BUM B;  4OC0 A;  4P4D A;  1Z9E A;  3VRN A;  2UV8 G;  2XPO A;  2JBJ A;  4OC1 A;  2Y1M A;  3IWW A;  4OC3 A;  3BXM A;  3FED A;  4NGM A;  5HKY A;  3BI0 A;  3FF3 A;  3VGO A;  4MCP A;  4P4J A;  3PLF B;  3BUN B;  4P4I A;  2PVV A;  3SJG A;  2XEG A;  3FEC A;  2CBL A;  3OAK A;  4BPW B;  3D7G A;  3HMJ G;  4NGP A;  4P4E A;  3PFV A;  5BY0 A;  1EO0 A;  4A4B A;  4P44 A;  5AXI A;  4P45 A;  5ELY A;  4GPL B;  4A4C A;  3BUX B;  2OR4 A;  4LQG A;  5HKZ A;  3SJF A;  3BI1 A;  3VRR A;  2XPL A;  1CX8 A;  1WJT A;  4JYW A;  1YVH A;  2C6G A;  2OOT A;  5D29 A;  2XEI A;  3D7D A;  4NGS A;  3D7H A;  2B4J C;  3OB1 B;  3PT1 A;  2DLA A;  1Z8L A;  2JBK A;  1B47 A;  4P4F A;  1FBV A;  4RR2 B;  3OB2 B;  3BUW B;  3HPH E;  2C6P A;  3VRO A;  3BUO B;  2XEJ A;  5HKW A;  3VRP A;  4NGT A;  4OC2 A;  3HPG G;  3FEE A;  3RBU A;  3S9M A;  4P4B A;  2CIJ A;  4NGN A;  4BPX B;  3SJE A;  3SJX A;  4NGQ A;  3S9N A;  3NFQ A;  4OC5 A;  3ZNI A;  4OC4 A;  4X3R A;  2XPN A;  2PVW A;  4JZ0 A;  3U88 C;  3VRQ A;  4NGR A;  3OP0 A;  4OME A;  2N3A B;  2XEF A;  2Y1N A;  2VKZ G;  4BPU B;  4BTF A;  3KAS A;  4MCR A;  5J3X A;  3F9K C;  1DE4 C;  2XPP A;  4MCS A;  5F09 A;  3D7F A;  3O8Z A;  4W9Y A; 
#chains in the Genus database with same CATH homology
 2VKZ G;  3PT1 A;  4RR2 B;  4BPX B;  4BPU B;  2DLA A;  5BY0 A;  5F13 A;  3HMJ G;  2UV8 G;  4BPW B; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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