2B4JC

Structural basis for the recognition between hiv-1 integrase and ledgf/p75
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
82
structure length
82
Chain Sequence
GSSMDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75
pubmed doi rcsb
molecule tags Viral protein, recombination
source organism Human immunodeficiency virus 1
molecule keywords Integrase (IN)
total genus 34
structure length 82
sequence length 82
chains with identical sequence D
ec nomenclature
pdb deposition date 2005-09-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.10 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 2b4jC00
2XPNA 3O8ZA 2N3AB 3NFQA 2B4JC 1WJTA 3OAKA 1EO0A 2XPOA 2XPPA 3F9KC 1Z9EA 3HPHE 2XPLA 3U88C 3HPGG
chains in the Genus database with same CATH superfamily
2OR4A 2PVVA 1EO0A 2JBJA 4BTFA 3D7HA 4P45A 5AXIA 3VRRA 2C6PA 2N3AB 4NGRA 4OC4A 3VROA 4OC0A 4OC2A 1CX8A 2XEIA 5D29A 4NGMA 4P4IA 4NGSA 4P4FA 5ELYA 3VRQA 4MCRA 3FF3A 2Y1NA 3F9KC 2XEJA 3RBUA 3FEDA 2C6GA 1B47A 4P4DA 4A4CA 2CBLA 4P4EA 4BPUB 3FEEA 4OC1A 2XEGA 3VRNA 3SJEA 3BI1A 3D7DA 4BPWB 3PT1A 4GPLB 5F09A 4OC5A 3SJXA 1WJTA 4MCQA 2XPPA 3KASA 4P4JA 4JZ0A 3OP0A 2XPNA 3BI0A 5BY0A 1Z9EA 1Z8LA 3BUXB 5F13A 2C6CA 3D7GA 3HPGG 3S9MA 3OB2B 2XPOA 3BHXA 4NGQA 3U88C 4BPXB 4JYWA 3BUMB 5J3XA 2DLAA 4MCPA 4NGPA 3VGOA 1DE4C 3S9NA 5HKWA 4RR2B 3ZNIA 4NGTA 2OOTA 3OB1B 2XPLA 2Y1MA 3PLFB 2XEFA 2JBKA 2PVWA 3O8ZA 4MCSA 2B4JC 3HPHE 4P44A 3BXMA 3BUNB 3HMJG 3D7FA 3BUOB 4OMEA 1YVHA 4LQGA 4NGNA 4A4BA 3VRPA 4X3RA 3FECA 2VKZG 4OC3A 3PFVA 3NFQA 3OAKA 3IWWA 3SJGA 3SJFA 4P4BA 5HKZA 3BUWB 4W9YA 3S9LA 2CIJA 5HKYA 2UV8G 1FBVA
chains in the Genus database with same CATH topology
2XPNA 3O8ZA 2N3AB 3NFQA 2B4JC 1WJTA 3OAKA 1EO0A 2XPOA 2XPPA 3F9KC 1Z9EA 3HPHE 2XPLA 3U88C 3HPGG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XPN A;  3O8Z A;  2N3A B;  3NFQ A;  2B4J C;  1WJT A;  3OAK A;  1EO0 A;  2XPO A;  2XPP A;  3F9K C;  1Z9E A;  3HPH E;  2XPL A;  3U88 C;  3HPG G; 
#chains in the Genus database with same CATH topology
 2OR4 A;  2PVV A;  1EO0 A;  2JBJ A;  4BTF A;  3D7H A;  4P45 A;  5AXI A;  3VRR A;  2C6P A;  2N3A B;  4NGR A;  4OC4 A;  3VRO A;  4OC0 A;  4OC2 A;  1CX8 A;  2XEI A;  5D29 A;  4NGM A;  4P4I A;  4NGS A;  4P4F A;  5ELY A;  3VRQ A;  4MCR A;  3FF3 A;  2Y1N A;  3F9K C;  2XEJ A;  3RBU A;  3FED A;  2C6G A;  1B47 A;  4P4D A;  4A4C A;  2CBL A;  4P4E A;  4BPU B;  3FEE A;  4OC1 A;  2XEG A;  3VRN A;  3SJE A;  3BI1 A;  3D7D A;  4BPW B;  3PT1 A;  4GPL B;  5F09 A;  4OC5 A;  3SJX A;  1WJT A;  4MCQ A;  2XPP A;  3KAS A;  4P4J A;  4JZ0 A;  3OP0 A;  2XPN A;  3BI0 A;  5BY0 A;  1Z9E A;  1Z8L A;  3BUX B;  5F13 A;  2C6C A;  3D7G A;  3HPG G;  3S9M A;  3OB2 B;  2XPO A;  3BHX A;  4NGQ A;  3U88 C;  4BPX B;  4JYW A;  3BUM B;  5J3X A;  2DLA A;  4MCP A;  4NGP A;  3VGO A;  1DE4 C;  3S9N A;  5HKW A;  4RR2 B;  3ZNI A;  4NGT A;  2OOT A;  3OB1 B;  2XPL A;  2Y1M A;  3PLF B;  2XEF A;  2JBK A;  2PVW A;  3O8Z A;  4MCS A;  2B4J C;  3HPH E;  4P44 A;  3BXM A;  3BUN B;  3HMJ G;  3D7F A;  3BUO B;  4OME A;  1YVH A;  4LQG A;  4NGN A;  4A4B A;  3VRP A;  4X3R A;  3FEC A;  2VKZ G;  4OC3 A;  3PFV A;  3NFQ A;  3OAK A;  3IWW A;  3SJG A;  3SJF A;  4P4B A;  5HKZ A;  3BUW B;  4W9Y A;  3S9L A;  2CIJ A;  5HKY A;  2UV8 G;  1FBV A; 
#chains in the Genus database with same CATH homology
 2XPN A;  3O8Z A;  2N3A B;  3NFQ A;  2B4J C;  1WJT A;  3OAK A;  1EO0 A;  2XPO A;  2XPP A;  3F9K C;  1Z9E A;  3HPH E;  2XPL A;  3U88 C;  3HPG G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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