2XPLA

Crystal structure of iws1(spn1) conserved domain from encephalitozoon cuniculi
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
142
structure length
142
Chain Sequence
HMDPGTVLEISRSLKKRMQDILKKDNANNLEGRPATGKIENVEEISDILMSKALQESLLDEGILDEIKGWLEPLPDKSMPNIKIRKRLLDVLKTMKIHKEHLVTSGVGKIVYFYSINPKESKEVRASAKALVQKWTNEVFKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of an Iws1/Spt6 Complex Reveals an Interaction Domain Conserved in Tfiis, Elongin a and Med26
pubmed doi rcsb
molecule tags Transcription
source organism Encephalitozoon cuniculi
molecule keywords IWS1
total genus 57
structure length 142
sequence length 142
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-08-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08711 Med26 TFIIS helical bundle-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.10 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 2xplA00
1WJTA 2XPNA 3OAKA 2B4JC 3HPGG 3HPHE 2XPPA 2XPLA 1EO0A 1Z9EA 3NFQA 3U88C 2N3AB 2XPOA 3O8ZA 3F9KC
chains in the Genus database with same CATH superfamily
4OMEA 4BPWB 2XEGA 4RR2B 1DE4C 3NFQA 4OC3A 5J3XA 2C6GA 2CBLA 4MCQA 3OP0A 5D29A 3BUWB 3VGOA 2DLAA 4JYWA 1WJTA 2PVWA 3FEEA 3RBUA 1CX8A 3F9KC 3D7DA 4JZ0A 4P44A 3BUNB 3D7FA 4OC4A 2C6CA 3IWWA 3PLFB 2XPNA 4P4JA 5AXIA 3O8ZA 1YVHA 2Y1NA 4OC5A 4P4DA 3SJXA 5BY0A 4MCRA 4NGMA 5HKWA 3U88C 3VRNA 3FEDA 3BI0A 4OC2A 2CIJA 4W9YA 2UV8G 3SJFA 3VROA 2C6PA 4NGSA 3PFVA 2OR4A 3KASA 2XPLA 4OC0A 1Z9EA 3S9LA 2N3AB 3D7HA 3SJGA 3OB1B 3S9MA 3D7GA 4BTFA 2JBJA 3ZNIA 3FECA 3HMJG 2XEFA 3OAKA 3SJEA 3HPGG 3BXMA 2OOTA 3BHXA 4P4IA 3VRQA 4A4CA 4LQGA 3PT1A 3VRPA 2PVVA 3BUMB 4GPLB 4P45A 3BUOB 2B4JC 3HPHE 5ELYA 2XPPA 5F09A 5HKYA 3S9NA 4MCPA 4NGPA 3VRRA 3BI1A 2XEIA 4BPXB 2JBKA 5HKZA 1EO0A 1B47A 2XPOA 3BUXB 4NGQA 4P4FA 2Y1MA 4A4BA 4P4EA 3OB2B 4OC1A 4BPUB 1Z8LA 2VKZG 4NGNA 3FF3A 5F13A 4NGRA 4X3RA 4NGTA 1FBVA 4MCSA 2XEJA 4P4BA
chains in the Genus database with same CATH topology
1WJTA 2XPNA 3OAKA 2B4JC 3HPGG 3HPHE 2XPPA 2XPLA 1EO0A 1Z9EA 3NFQA 3U88C 2N3AB 2XPOA 3O8ZA 3F9KC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WJT A;  2XPN A;  3OAK A;  2B4J C;  3HPG G;  3HPH E;  2XPP A;  2XPL A;  1EO0 A;  1Z9E A;  3NFQ A;  3U88 C;  2N3A B;  2XPO A;  3O8Z A;  3F9K C; 
#chains in the Genus database with same CATH topology
 4OME A;  4BPW B;  2XEG A;  4RR2 B;  1DE4 C;  3NFQ A;  4OC3 A;  5J3X A;  2C6G A;  2CBL A;  4MCQ A;  3OP0 A;  5D29 A;  3BUW B;  3VGO A;  2DLA A;  4JYW A;  1WJT A;  2PVW A;  3FEE A;  3RBU A;  1CX8 A;  3F9K C;  3D7D A;  4JZ0 A;  4P44 A;  3BUN B;  3D7F A;  4OC4 A;  2C6C A;  3IWW A;  3PLF B;  2XPN A;  4P4J A;  5AXI A;  3O8Z A;  1YVH A;  2Y1N A;  4OC5 A;  4P4D A;  3SJX A;  5BY0 A;  4MCR A;  4NGM A;  5HKW A;  3U88 C;  3VRN A;  3FED A;  3BI0 A;  4OC2 A;  2CIJ A;  4W9Y A;  2UV8 G;  3SJF A;  3VRO A;  2C6P A;  4NGS A;  3PFV A;  2OR4 A;  3KAS A;  2XPL A;  4OC0 A;  1Z9E A;  3S9L A;  2N3A B;  3D7H A;  3SJG A;  3OB1 B;  3S9M A;  3D7G A;  4BTF A;  2JBJ A;  3ZNI A;  3FEC A;  3HMJ G;  2XEF A;  3OAK A;  3SJE A;  3HPG G;  3BXM A;  2OOT A;  3BHX A;  4P4I A;  3VRQ A;  4A4C A;  4LQG A;  3PT1 A;  3VRP A;  2PVV A;  3BUM B;  4GPL B;  4P45 A;  3BUO B;  2B4J C;  3HPH E;  5ELY A;  2XPP A;  5F09 A;  5HKY A;  3S9N A;  4MCP A;  4NGP A;  3VRR A;  3BI1 A;  2XEI A;  4BPX B;  2JBK A;  5HKZ A;  1EO0 A;  1B47 A;  2XPO A;  3BUX B;  4NGQ A;  4P4F A;  2Y1M A;  4A4B A;  4P4E A;  3OB2 B;  4OC1 A;  4BPU B;  1Z8L A;  2VKZ G;  4NGN A;  3FF3 A;  5F13 A;  4NGR A;  4X3R A;  4NGT A;  1FBV A;  4MCS A;  2XEJ A;  4P4B A; 
#chains in the Genus database with same CATH homology
 1WJT A;  2XPN A;  3OAK A;  2B4J C;  3HPG G;  3HPH E;  2XPP A;  2XPL A;  1EO0 A;  1Z9E A;  3NFQ A;  3U88 C;  2N3A B;  2XPO A;  3O8Z A;  3F9K C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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