2XPLA

Crystal structure of iws1(spn1) conserved domain from encephalitozoon cuniculi
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
142
structure length
142
Chain Sequence
HMDPGTVLEISRSLKKRMQDILKKDNANNLEGRPATGKIENVEEISDILMSKALQESLLDEGILDEIKGWLEPLPDKSMPNIKIRKRLLDVLKTMKIHKEHLVTSGVGKIVYFYSINPKESKEVRASAKALVQKWTNEVFKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of an Iws1/Spt6 Complex Reveals an Interaction Domain Conserved in Tfiis, Elongin a and Med26
pubmed doi rcsb
molecule tags Transcription
source organism Encephalitozoon cuniculi
molecule keywords IWS1
total genus 57
structure length 142
sequence length 142
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-08-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08711 Med26 TFIIS helical bundle-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.10 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 2xplA00
2XPNA 3NFQA 2XPOA 3U88C 3HPGG 2XPLA 3O8ZA 3OAKA 2N3AB 1EO0A 3F9KC 1WJTA 1Z9EA 2B4JC 2XPPA 3HPHE
chains in the Genus database with same CATH superfamily
4P44A 3VRRA 2JBJA 4NGQA 3OP0A 3BUOB 4NGPA 5ELYA 1Z8LA 3VRNA 3FF3A 2XPOA 5F09A 5AXIA 3FEDA 2CBLA 1Z9EA 3BUNB 3OB1B 3SJFA 3IWWA 3D7GA 4JZ0A 4OC5A 3RBUA 1EO0A 3VRQA 2PVWA 4JYWA 3SJEA 3HMJG 5J3XA 4OC2A 3PLFB 5HKYA 2OOTA 3U88C 4NGSA 3O8ZA 2UV8G 4NGRA 3S9MA 3F9KC 4BPXB 4A4BA 4MCSA 4LQGA 2Y1MA 3OAKA 3VGOA 3PFVA 3BXMA 4OC4A 4P4IA 4P4JA 3BUXB 2VKZG 2OR4A 3FECA 3VRPA 1B47A 4OMEA 2B4JC 2PVVA 4GPLB 3BUWB 4P4FA 4W9YA 3S9NA 3VROA 2N3AB 5D29A 3HPHE 3PT1A 4OC0A 3NFQA 4NGTA 4NGNA 3D7HA 2XEGA 2C6PA 1CX8A 4P4DA 3SJXA 5F13A 1YVHA 4MCQA 2XEFA 3BUMB 3BI1A 3BHXA 2XPNA 3KASA 5HKWA 3HPGG 4BPUB 4RR2B 4OC3A 4X3RA 2C6GA 1WJTA 2Y1NA 3D7FA 4MCPA 4OC1A 4BTFA 4MCRA 3OB2B 2XPLA 1DE4C 4P45A 4A4CA 3ZNIA 2XEJA 2CIJA 5BY0A 4P4BA 2JBKA 1FBVA 4BPWB 5HKZA 4NGMA 3D7DA 3SJGA 3S9LA 3FEEA 2DLAA 4P4EA 3BI0A 2XPPA 2XEIA 2C6CA
chains in the Genus database with same CATH topology
2XPNA 3NFQA 2XPOA 3U88C 3HPGG 2XPLA 3O8ZA 3OAKA 2N3AB 1EO0A 3F9KC 1WJTA 1Z9EA 2B4JC 2XPPA 3HPHE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XPN A;  3NFQ A;  2XPO A;  3U88 C;  3HPG G;  2XPL A;  3O8Z A;  3OAK A;  2N3A B;  1EO0 A;  3F9K C;  1WJT A;  1Z9E A;  2B4J C;  2XPP A;  3HPH E; 
#chains in the Genus database with same CATH topology
 4P44 A;  3VRR A;  2JBJ A;  4NGQ A;  3OP0 A;  3BUO B;  4NGP A;  5ELY A;  1Z8L A;  3VRN A;  3FF3 A;  2XPO A;  5F09 A;  5AXI A;  3FED A;  2CBL A;  1Z9E A;  3BUN B;  3OB1 B;  3SJF A;  3IWW A;  3D7G A;  4JZ0 A;  4OC5 A;  3RBU A;  1EO0 A;  3VRQ A;  2PVW A;  4JYW A;  3SJE A;  3HMJ G;  5J3X A;  4OC2 A;  3PLF B;  5HKY A;  2OOT A;  3U88 C;  4NGS A;  3O8Z A;  2UV8 G;  4NGR A;  3S9M A;  3F9K C;  4BPX B;  4A4B A;  4MCS A;  4LQG A;  2Y1M A;  3OAK A;  3VGO A;  3PFV A;  3BXM A;  4OC4 A;  4P4I A;  4P4J A;  3BUX B;  2VKZ G;  2OR4 A;  3FEC A;  3VRP A;  1B47 A;  4OME A;  2B4J C;  2PVV A;  4GPL B;  3BUW B;  4P4F A;  4W9Y A;  3S9N A;  3VRO A;  2N3A B;  5D29 A;  3HPH E;  3PT1 A;  4OC0 A;  3NFQ A;  4NGT A;  4NGN A;  3D7H A;  2XEG A;  2C6P A;  1CX8 A;  4P4D A;  3SJX A;  5F13 A;  1YVH A;  4MCQ A;  2XEF A;  3BUM B;  3BI1 A;  3BHX A;  2XPN A;  3KAS A;  5HKW A;  3HPG G;  4BPU B;  4RR2 B;  4OC3 A;  4X3R A;  2C6G A;  1WJT A;  2Y1N A;  3D7F A;  4MCP A;  4OC1 A;  4BTF A;  4MCR A;  3OB2 B;  2XPL A;  1DE4 C;  4P45 A;  4A4C A;  3ZNI A;  2XEJ A;  2CIJ A;  5BY0 A;  4P4B A;  2JBK A;  1FBV A;  4BPW B;  5HKZ A;  4NGM A;  3D7D A;  3SJG A;  3S9L A;  3FEE A;  2DLA A;  4P4E A;  3BI0 A;  2XPP A;  2XEI A;  2C6C A; 
#chains in the Genus database with same CATH homology
 2XPN A;  3NFQ A;  2XPO A;  3U88 C;  3HPG G;  2XPL A;  3O8Z A;  3OAK A;  2N3A B;  1EO0 A;  3F9K C;  1WJT A;  1Z9E A;  2B4J C;  2XPP A;  3HPH E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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