2XPOA

Crystal structure of a spt6-iws1(spn1) complex from encephalitozoon cuniculi, form ii
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
139
structure length
139
Chain Sequence
MDPGTVLEISRSLKKRMQDILKKDNANNLEGRPATGKIENVEEISDILMSKALQESLLDEGILDEIKGWLEPLPDKSMPNIKIRKRLLDVLKTMKIHKEHLVTSGVGKIVYFYSINPKESKEVRASAKALVQKWTNEVF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
source organism Encephalitozoon cuniculi
publication title The Structure of an Iws1/Spt6 Complex Reveals an Interaction Domain Conserved in Tfiis, Elongin a and Med26
pubmed doi rcsb
molecule keywords IWS1
total genus 57
structure length 139
sequence length 139
chains with identical sequence C
ec nomenclature
pdb deposition date 2010-08-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08711 Med26 TFIIS helical bundle-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.10 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 2xpoA00
3U88C 2B4JC 1Z9EA 1WJTA 2XPNA 2N3AB 3NFQA 1EO0A 2XPPA 3O8ZA 3HPHE 3HPGG 2XPOA 3OAKA 2XPLA 3F9KC
chains in the Genus database with same CATH superfamily
2XEIA 5AXIA 2XPPA 2C6GA 4BPXB 2XPLA 3D7DA 4A4BA 2JBJA 3D7FA 2C6CA 4LQGA 4W9YA 4P44A 3BUOB 3BUNB 2VKZG 4RR2B 2DLAA 2PVVA 2JBKA 5ELYA 3U88C 2B4JC 4P4FA 4P4BA 4OC5A 3SJGA 3PT1A 2XPNA 3FEEA 4MCRA 4NGQA 3BI1A 5F13A 2Y1MA 4OMEA 3OAKA 1B47A 3HMJG 1EO0A 4NGNA 4P4EA 2N3AB 3ZNIA 3HPHE 2UV8G 3S9LA 5HKWA 3VRQA 3BHXA 3VGOA 4BTFA 3IWWA 4P45A 3SJEA 1WJTA 1CX8A 4NGRA 2Y1NA 3OB1B 2XEJA 3FF3A 5HKZA 3RBUA 4MCQA 4OC3A 3S9NA 3BI0A 5HKYA 3OP0A 2XPOA 3FECA 2XEFA 3FEDA 3VRNA 4P4DA 3NFQA 3O8ZA 2C6PA 4BPWB 4GPLB 5BY0A 4JZ0A 4NGPA 4MCPA 3VRRA 3PLFB 4OC4A 2XEGA 4OC0A 4NGSA 1Z9EA 1Z8LA 2CBLA 3KASA 4OC2A 2PVWA 3S9MA 3BUMB 4BPUB 3SJXA 3VRPA 2CIJA 3D7HA 4NGTA 5J3XA 3BUWB 3BXMA 3HPGG 3BUXB 5D29A 3PFVA 4JYWA 1FBVA 4A4CA 4X3RA 3VROA 2OR4A 4P4IA 4MCSA 3D7GA 1DE4C 4OC1A 4P4JA 3F9KC 4NGMA 2OOTA 3SJFA 3OB2B 1YVHA 5F09A
chains in the Genus database with same CATH topology
3U88C 2B4JC 1Z9EA 1WJTA 2XPNA 2N3AB 3NFQA 1EO0A 2XPPA 3O8ZA 3HPHE 3HPGG 2XPOA 3OAKA 2XPLA 3F9KC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3U88 C;  2B4J C;  1Z9E A;  1WJT A;  2XPN A;  2N3A B;  3NFQ A;  1EO0 A;  2XPP A;  3O8Z A;  3HPH E;  3HPG G;  2XPO A;  3OAK A;  2XPL A;  3F9K C; 
#chains in the Genus database with same CATH topology
 2XEI A;  5AXI A;  2XPP A;  2C6G A;  4BPX B;  2XPL A;  3D7D A;  4A4B A;  2JBJ A;  3D7F A;  2C6C A;  4LQG A;  4W9Y A;  4P44 A;  3BUO B;  3BUN B;  2VKZ G;  4RR2 B;  2DLA A;  2PVV A;  2JBK A;  5ELY A;  3U88 C;  2B4J C;  4P4F A;  4P4B A;  4OC5 A;  3SJG A;  3PT1 A;  2XPN A;  3FEE A;  4MCR A;  4NGQ A;  3BI1 A;  5F13 A;  2Y1M A;  4OME A;  3OAK A;  1B47 A;  3HMJ G;  1EO0 A;  4NGN A;  4P4E A;  2N3A B;  3ZNI A;  3HPH E;  2UV8 G;  3S9L A;  5HKW A;  3VRQ A;  3BHX A;  3VGO A;  4BTF A;  3IWW A;  4P45 A;  3SJE A;  1WJT A;  1CX8 A;  4NGR A;  2Y1N A;  3OB1 B;  2XEJ A;  3FF3 A;  5HKZ A;  3RBU A;  4MCQ A;  4OC3 A;  3S9N A;  3BI0 A;  5HKY A;  3OP0 A;  2XPO A;  3FEC A;  2XEF A;  3FED A;  3VRN A;  4P4D A;  3NFQ A;  3O8Z A;  2C6P A;  4BPW B;  4GPL B;  5BY0 A;  4JZ0 A;  4NGP A;  4MCP A;  3VRR A;  3PLF B;  4OC4 A;  2XEG A;  4OC0 A;  4NGS A;  1Z9E A;  1Z8L A;  2CBL A;  3KAS A;  4OC2 A;  2PVW A;  3S9M A;  3BUM B;  4BPU B;  3SJX A;  3VRP A;  2CIJ A;  3D7H A;  4NGT A;  5J3X A;  3BUW B;  3BXM A;  3HPG G;  3BUX B;  5D29 A;  3PFV A;  4JYW A;  1FBV A;  4A4C A;  4X3R A;  3VRO A;  2OR4 A;  4P4I A;  4MCS A;  3D7G A;  1DE4 C;  4OC1 A;  4P4J A;  3F9K C;  4NGM A;  2OOT A;  3SJF A;  3OB2 B;  1YVH A;  5F09 A; 
#chains in the Genus database with same CATH homology
 3U88 C;  2B4J C;  1Z9E A;  1WJT A;  2XPN A;  2N3A B;  3NFQ A;  1EO0 A;  2XPP A;  3O8Z A;  3HPH E;  3HPG G;  2XPO A;  3OAK A;  2XPL A;  3F9K C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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