3HPGG

Visna virus integrase (residues 1-219) in complex with ledgf ibd: examples of open integrase dimer-dimer interfaces
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
76
structure length
73
Chain Sequence
MDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for functional tetramerization of lentiviral integrase
pubmed doi rcsb
molecule tags Transferase
source organism Maedi visna virus
molecule keywords Integrase
total genus 16
structure length 73
sequence length 76
chains with identical sequence H, I, J, K, L
ec nomenclature
pdb deposition date 2009-06-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.10 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 3hpgG00
3OAKA 2XPLA 3HPGG 3F9KC 3U88C 2XPOA 2XPPA 1WJTA 3HPHE 1EO0A 2N3AB 1Z9EA 3NFQA 3O8ZA 2B4JC 2XPNA
chains in the Genus database with same CATH superfamily
2OR4A 3HPHE 3KASA 4P45A 5BY0A 2DLAA 4X3RA 2C6PA 3IWWA 4P4EA 1FBVA 3HPGG 4JYWA 3FEEA 4NGRA 4GPLB 3BHXA 4P4BA 3FECA 3S9LA 1EO0A 2Y1MA 3D7DA 3BI1A 3VRPA 4OC5A 5F09A 3ZNIA 4OC3A 2XEJA 2Y1NA 3SJXA 3BUNB 4OC2A 4OC4A 3D7GA 4NGPA 2PVWA 4P4IA 2N3AB 2JBJA 4BTFA 4NGQA 3OAKA 4MCSA 4MCPA 2CBLA 3SJEA 4RR2B 1WJTA 5AXIA 4BPXB 3PLFB 4NGMA 1YVHA 4LQGA 4W9YA 2PVVA 5HKWA 2CIJA 3F9KC 3VGOA 3HMJG 5HKZA 3U88C 4MCQA 3FEDA 3OB2B 3VRNA 4P44A 3VRRA 4JZ0A 1CX8A 3RBUA 4A4BA 4BPWB 5HKYA 2B4JC 3D7HA 4OMEA 2C6CA 5D29A 2UV8G 2JBKA 3OP0A 4NGTA 2XPLA 2XPOA 1Z8LA 2XPPA 3BXMA 3BUXB 3BUMB 3VROA 1DE4C 4BPUB 4P4FA 3D7FA 3PFVA 4P4DA 2XEGA 3VRQA 3O8ZA 4A4CA 2XPNA 3SJFA 4MCRA 5J3XA 3OB1B 4NGNA 4NGSA 4P4JA 1Z9EA 2C6GA 4OC1A 2XEIA 3S9MA 5ELYA 3FF3A 3BUOB 4OC0A 2XEFA 3PT1A 2OOTA 3BI0A 3BUWB 3NFQA 1B47A 3SJGA 2VKZG 5F13A 3S9NA
chains in the Genus database with same CATH topology
3OAKA 2XPLA 3HPGG 3F9KC 3U88C 2XPOA 2XPPA 1WJTA 3HPHE 1EO0A 2N3AB 1Z9EA 3NFQA 3O8ZA 2B4JC 2XPNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OAK A;  2XPL A;  3HPG G;  3F9K C;  3U88 C;  2XPO A;  2XPP A;  1WJT A;  3HPH E;  1EO0 A;  2N3A B;  1Z9E A;  3NFQ A;  3O8Z A;  2B4J C;  2XPN A; 
#chains in the Genus database with same CATH topology
 2OR4 A;  3HPH E;  3KAS A;  4P45 A;  5BY0 A;  2DLA A;  4X3R A;  2C6P A;  3IWW A;  4P4E A;  1FBV A;  3HPG G;  4JYW A;  3FEE A;  4NGR A;  4GPL B;  3BHX A;  4P4B A;  3FEC A;  3S9L A;  1EO0 A;  2Y1M A;  3D7D A;  3BI1 A;  3VRP A;  4OC5 A;  5F09 A;  3ZNI A;  4OC3 A;  2XEJ A;  2Y1N A;  3SJX A;  3BUN B;  4OC2 A;  4OC4 A;  3D7G A;  4NGP A;  2PVW A;  4P4I A;  2N3A B;  2JBJ A;  4BTF A;  4NGQ A;  3OAK A;  4MCS A;  4MCP A;  2CBL A;  3SJE A;  4RR2 B;  1WJT A;  5AXI A;  4BPX B;  3PLF B;  4NGM A;  1YVH A;  4LQG A;  4W9Y A;  2PVV A;  5HKW A;  2CIJ A;  3F9K C;  3VGO A;  3HMJ G;  5HKZ A;  3U88 C;  4MCQ A;  3FED A;  3OB2 B;  3VRN A;  4P44 A;  3VRR A;  4JZ0 A;  1CX8 A;  3RBU A;  4A4B A;  4BPW B;  5HKY A;  2B4J C;  3D7H A;  4OME A;  2C6C A;  5D29 A;  2UV8 G;  2JBK A;  3OP0 A;  4NGT A;  2XPL A;  2XPO A;  1Z8L A;  2XPP A;  3BXM A;  3BUX B;  3BUM B;  3VRO A;  1DE4 C;  4BPU B;  4P4F A;  3D7F A;  3PFV A;  4P4D A;  2XEG A;  3VRQ A;  3O8Z A;  4A4C A;  2XPN A;  3SJF A;  4MCR A;  5J3X A;  3OB1 B;  4NGN A;  4NGS A;  4P4J A;  1Z9E A;  2C6G A;  4OC1 A;  2XEI A;  3S9M A;  5ELY A;  3FF3 A;  3BUO B;  4OC0 A;  2XEF A;  3PT1 A;  2OOT A;  3BI0 A;  3BUW B;  3NFQ A;  1B47 A;  3SJG A;  2VKZ G;  5F13 A;  3S9N A; 
#chains in the Genus database with same CATH homology
 3OAK A;  2XPL A;  3HPG G;  3F9K C;  3U88 C;  2XPO A;  2XPP A;  1WJT A;  3HPH E;  1EO0 A;  2N3A B;  1Z9E A;  3NFQ A;  3O8Z A;  2B4J C;  2XPN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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