3HPGG

Visna virus integrase (residues 1-219) in complex with ledgf ibd: examples of open integrase dimer-dimer interfaces
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
76
structure length
73
Chain Sequence
MDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for functional tetramerization of lentiviral integrase
pubmed doi rcsb
molecule keywords Integrase
molecule tags Transferase
source organism Maedi visna virus
total genus 16
structure length 73
sequence length 76
chains with identical sequence H, I, J, K, L
ec nomenclature
pdb deposition date 2009-06-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.10 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 3hpgG00
3U88C 1Z9EA 2XPPA 3HPHE 3F9KC 2XPLA 2XPOA 3OAKA 1EO0A 3NFQA 2B4JC 3HPGG 2N3AB 3O8ZA 2XPNA 1WJTA
chains in the Genus database with same CATH superfamily
3RBUA 3SJGA 4P4JA 4P4FA 2JBKA 2PVWA 4JZ0A 4W9YA 4NGQA 3BUMB 4NGPA 3SJXA 5BY0A 4A4CA 4MCSA 3BUNB 3BUXB 3VRRA 3S9MA 2XEGA 2XEIA 3SJFA 3FECA 3ZNIA 3BHXA 3D7DA 4BPXB 3VGOA 3D7FA 4MCRA 4MCQA 3FEEA 2XPPA 4OC3A 4NGNA 2OOTA 4NGSA 3PT1A 1FBVA 2XPLA 2XPOA 3IWWA 3FF3A 3BI0A 2JBJA 3NFQA 4P4EA 4X3RA 5ELYA 2Y1MA 3VRPA 3HPGG 4P44A 2N3AB 2VKZG 3U88C 1B47A 2CBLA 3D7HA 3OP0A 4NGTA 3HMJG 5D29A 3BUWB 3S9NA 4JYWA 4P4IA 4OC1A 3BI1A 2DLAA 4MCPA 4P4BA 4GPLB 5AXIA 1EO0A 3OAKA 3BXMA 1DE4C 4OMEA 3D7GA 3VRNA 4P4DA 3SJEA 5HKZA 2OR4A 5F13A 4BTFA 4LQGA 2CIJA 5F09A 4OC2A 3KASA 5HKWA 4A4BA 3S9LA 4OC4A 2XEJA 3BUOB 1Z9EA 4BPWB 4P45A 1CX8A 1YVHA 3VROA 2XPNA 3HPHE 4OC5A 3F9KC 4OC0A 2PVVA 2UV8G 4BPUB 5J3XA 3PLFB 4RR2B 2C6PA 2Y1NA 3PFVA 3FEDA 4NGRA 1WJTA 2C6CA 3OB2B 3VRQA 4NGMA 1Z8LA 5HKYA 2C6GA 2B4JC 3OB1B 3O8ZA 2XEFA
chains in the Genus database with same CATH topology
3U88C 1Z9EA 2XPPA 3HPHE 3F9KC 2XPLA 2XPOA 3OAKA 1EO0A 3NFQA 2B4JC 3HPGG 2N3AB 3O8ZA 2XPNA 1WJTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3U88 C;  1Z9E A;  2XPP A;  3HPH E;  3F9K C;  2XPL A;  2XPO A;  3OAK A;  1EO0 A;  3NFQ A;  2B4J C;  3HPG G;  2N3A B;  3O8Z A;  2XPN A;  1WJT A; 
#chains in the Genus database with same CATH topology
 3RBU A;  3SJG A;  4P4J A;  4P4F A;  2JBK A;  2PVW A;  4JZ0 A;  4W9Y A;  4NGQ A;  3BUM B;  4NGP A;  3SJX A;  5BY0 A;  4A4C A;  4MCS A;  3BUN B;  3BUX B;  3VRR A;  3S9M A;  2XEG A;  2XEI A;  3SJF A;  3FEC A;  3ZNI A;  3BHX A;  3D7D A;  4BPX B;  3VGO A;  3D7F A;  4MCR A;  4MCQ A;  3FEE A;  2XPP A;  4OC3 A;  4NGN A;  2OOT A;  4NGS A;  3PT1 A;  1FBV A;  2XPL A;  2XPO A;  3IWW A;  3FF3 A;  3BI0 A;  2JBJ A;  3NFQ A;  4P4E A;  4X3R A;  5ELY A;  2Y1M A;  3VRP A;  3HPG G;  4P44 A;  2N3A B;  2VKZ G;  3U88 C;  1B47 A;  2CBL A;  3D7H A;  3OP0 A;  4NGT A;  3HMJ G;  5D29 A;  3BUW B;  3S9N A;  4JYW A;  4P4I A;  4OC1 A;  3BI1 A;  2DLA A;  4MCP A;  4P4B A;  4GPL B;  5AXI A;  1EO0 A;  3OAK A;  3BXM A;  1DE4 C;  4OME A;  3D7G A;  3VRN A;  4P4D A;  3SJE A;  5HKZ A;  2OR4 A;  5F13 A;  4BTF A;  4LQG A;  2CIJ A;  5F09 A;  4OC2 A;  3KAS A;  5HKW A;  4A4B A;  3S9L A;  4OC4 A;  2XEJ A;  3BUO B;  1Z9E A;  4BPW B;  4P45 A;  1CX8 A;  1YVH A;  3VRO A;  2XPN A;  3HPH E;  4OC5 A;  3F9K C;  4OC0 A;  2PVV A;  2UV8 G;  4BPU B;  5J3X A;  3PLF B;  4RR2 B;  2C6P A;  2Y1N A;  3PFV A;  3FED A;  4NGR A;  1WJT A;  2C6C A;  3OB2 B;  3VRQ A;  4NGM A;  1Z8L A;  5HKY A;  2C6G A;  2B4J C;  3OB1 B;  3O8Z A;  2XEF A; 
#chains in the Genus database with same CATH homology
 3U88 C;  1Z9E A;  2XPP A;  3HPH E;  3F9K C;  2XPL A;  2XPO A;  3OAK A;  1EO0 A;  3NFQ A;  2B4J C;  3HPG G;  2N3A B;  3O8Z A;  2XPN A;  1WJT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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