3HPHE

Closed tetramer of visna virus integrase (residues 1-219) in complex with ledgf ibd
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
93
structure length
89
Chain Sequence
MDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLVSVLEVLF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for functional tetramerization of lentiviral integrase
pubmed doi rcsb
molecule tags Transferase
source organism Maedi visna virus
molecule keywords Integrase
total genus 28
structure length 89
sequence length 93
chains with identical sequence F, G, H
ec nomenclature
pdb deposition date 2009-06-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.10 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 3hphE00
3U88C 1EO0A 1Z9EA 3HPHE 2XPPA 3HPGG 3NFQA 2B4JC 2XPLA 3F9KC 1WJTA 2N3AB 3O8ZA 3OAKA 2XPNA 2XPOA
chains in the Genus database with same CATH superfamily
4NGPA 4OMEA 4NGQA 3FEEA 3SJGA 2XEJA 3NFQA 2PVWA 4P4FA 1DE4C 4P4EA 3U88C 3VGOA 3VRQA 2JBKA 3BXMA 3HPGG 3SJXA 2XEFA 3BUWB 2XEGA 4OC1A 2Y1MA 4P45A 3OB2B 3OB1B 3RBUA 1YVHA 3VRRA 4A4CA 3BI0A 5HKYA 3O8ZA 3BUXB 3FF3A 3D7FA 3BUNB 2JBJA 4BPXB 4JYWA 5D29A 1Z9EA 4JZ0A 2CIJA 4RR2B 3PT1A 4OC3A 3SJEA 1Z8LA 3BHXA 5BY0A 4MCPA 2VKZG 2DLAA 3KASA 2OOTA 3ZNIA 3S9NA 5HKZA 4P4JA 3VROA 2N3AB 4OC5A 4NGTA 1CX8A 4OC2A 5F13A 2XPPA 4A4BA 3BUOB 4BPWB 2Y1NA 5ELYA 4MCRA 1FBVA 4NGMA 3PFVA 2UV8G 2C6CA 4OC0A 3OAKA 2C6GA 4W9YA 3D7GA 4OC4A 3PLFB 4P4DA 3HPHE 4P4BA 4BTFA 2OR4A 3FEDA 3VRNA 3S9MA 2C6PA 4MCSA 5F09A 3BI1A 1B47A 1WJTA 2XEIA 2XPNA 3IWWA 4P4IA 4NGNA 3BUMB 4MCQA 3VRPA 3SJFA 5AXIA 5HKWA 3S9LA 3HMJG 3D7DA 2XPOA 4NGSA 3D7HA 4NGRA 2B4JC 3F9KC 3FECA 4BPUB 4LQGA 4X3RA 2PVVA 1EO0A 4GPLB 2XPLA 4P44A 2CBLA 5J3XA 3OP0A
chains in the Genus database with same CATH topology
3U88C 1EO0A 1Z9EA 3HPHE 2XPPA 3HPGG 3NFQA 2B4JC 2XPLA 3F9KC 1WJTA 2N3AB 3O8ZA 3OAKA 2XPNA 2XPOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3U88 C;  1EO0 A;  1Z9E A;  3HPH E;  2XPP A;  3HPG G;  3NFQ A;  2B4J C;  2XPL A;  3F9K C;  1WJT A;  2N3A B;  3O8Z A;  3OAK A;  2XPN A;  2XPO A; 
#chains in the Genus database with same CATH topology
 4NGP A;  4OME A;  4NGQ A;  3FEE A;  3SJG A;  2XEJ A;  3NFQ A;  2PVW A;  4P4F A;  1DE4 C;  4P4E A;  3U88 C;  3VGO A;  3VRQ A;  2JBK A;  3BXM A;  3HPG G;  3SJX A;  2XEF A;  3BUW B;  2XEG A;  4OC1 A;  2Y1M A;  4P45 A;  3OB2 B;  3OB1 B;  3RBU A;  1YVH A;  3VRR A;  4A4C A;  3BI0 A;  5HKY A;  3O8Z A;  3BUX B;  3FF3 A;  3D7F A;  3BUN B;  2JBJ A;  4BPX B;  4JYW A;  5D29 A;  1Z9E A;  4JZ0 A;  2CIJ A;  4RR2 B;  3PT1 A;  4OC3 A;  3SJE A;  1Z8L A;  3BHX A;  5BY0 A;  4MCP A;  2VKZ G;  2DLA A;  3KAS A;  2OOT A;  3ZNI A;  3S9N A;  5HKZ A;  4P4J A;  3VRO A;  2N3A B;  4OC5 A;  4NGT A;  1CX8 A;  4OC2 A;  5F13 A;  2XPP A;  4A4B A;  3BUO B;  4BPW B;  2Y1N A;  5ELY A;  4MCR A;  1FBV A;  4NGM A;  3PFV A;  2UV8 G;  2C6C A;  4OC0 A;  3OAK A;  2C6G A;  4W9Y A;  3D7G A;  4OC4 A;  3PLF B;  4P4D A;  3HPH E;  4P4B A;  4BTF A;  2OR4 A;  3FED A;  3VRN A;  3S9M A;  2C6P A;  4MCS A;  5F09 A;  3BI1 A;  1B47 A;  1WJT A;  2XEI A;  2XPN A;  3IWW A;  4P4I A;  4NGN A;  3BUM B;  4MCQ A;  3VRP A;  3SJF A;  5AXI A;  5HKW A;  3S9L A;  3HMJ G;  3D7D A;  2XPO A;  4NGS A;  3D7H A;  4NGR A;  2B4J C;  3F9K C;  3FEC A;  4BPU B;  4LQG A;  4X3R A;  2PVV A;  1EO0 A;  4GPL B;  2XPL A;  4P44 A;  2CBL A;  5J3X A;  3OP0 A; 
#chains in the Genus database with same CATH homology
 3U88 C;  1EO0 A;  1Z9E A;  3HPH E;  2XPP A;  3HPG G;  3NFQ A;  2B4J C;  2XPL A;  3F9K C;  1WJT A;  2N3A B;  3O8Z A;  3OAK A;  2XPN A;  2XPO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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