3HPHE

Closed tetramer of visna virus integrase (residues 1-219) in complex with ledgf ibd
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
93
structure length
89
Chain Sequence
MDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLVSVLEVLF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for functional tetramerization of lentiviral integrase
pubmed doi rcsb
molecule tags Transferase
source organism Maedi visna virus
molecule keywords Integrase
total genus 28
structure length 89
sequence length 93
chains with identical sequence F, G, H
ec nomenclature
pdb deposition date 2009-06-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.10 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 3hphE00
3NFQA 3OAKA 2XPNA 1Z9EA 1EO0A 3O8ZA 3HPHE 2XPLA 2N3AB 2XPOA 2XPPA 3F9KC 3HPGG 1WJTA 2B4JC 3U88C
chains in the Genus database with same CATH superfamily
4NGTA 4A4BA 5BY0A 4MCQA 3S9MA 5AXIA 3S9NA 3VRQA 3PLFB 3BHXA 4OC1A 2B4JC 4NGNA 3PT1A 3RBUA 4P4JA 3ZNIA 1B47A 3HMJG 3D7FA 2VKZG 5F09A 3F9KC 4NGRA 4OC4A 2XEFA 2PVWA 4NGPA 1YVHA 1DE4C 4OMEA 4P4EA 3FF3A 2C6PA 3VROA 1CX8A 3IWWA 2DLAA 1WJTA 5D29A 4P4DA 4OC2A 1Z8LA 4W9YA 4BPWB 3D7HA 2XPOA 4JZ0A 2XEJA 3BUWB 5HKZA 4OC0A 3SJEA 2XPNA 1Z9EA 3BUNB 3D7GA 3BUMB 2CIJA 2JBJA 2OOTA 3D7DA 3VRPA 3BXMA 4MCPA 3HPGG 4GPLB 4P4FA 3KASA 3PFVA 1EO0A 4RR2B 2XPLA 3U88C 4NGSA 2JBKA 3OAKA 4P4IA 4JYWA 3VRRA 2UV8G 3SJXA 4MCRA 3O8ZA 3BUOB 2XPPA 4X3RA 2C6GA 4A4CA 4P4BA 1FBVA 5HKWA 3HPHE 4P45A 3SJGA 5HKYA 2C6CA 3VGOA 5ELYA 4MCSA 4BPXB 5F13A 3S9LA 2Y1NA 4NGMA 3BI0A 4P44A 4BPUB 2OR4A 2Y1MA 3BUXB 5J3XA 2PVVA 2CBLA 3OB2B 3FEDA 3OP0A 3BI1A 4NGQA 4OC3A 2XEGA 3OB1B 3SJFA 3FEEA 3NFQA 3VRNA 4OC5A 2N3AB 2XEIA 4LQGA 4BTFA 3FECA
chains in the Genus database with same CATH topology
3NFQA 3OAKA 2XPNA 1Z9EA 1EO0A 3O8ZA 3HPHE 2XPLA 2N3AB 2XPOA 2XPPA 3F9KC 3HPGG 1WJTA 2B4JC 3U88C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NFQ A;  3OAK A;  2XPN A;  1Z9E A;  1EO0 A;  3O8Z A;  3HPH E;  2XPL A;  2N3A B;  2XPO A;  2XPP A;  3F9K C;  3HPG G;  1WJT A;  2B4J C;  3U88 C; 
#chains in the Genus database with same CATH topology
 4NGT A;  4A4B A;  5BY0 A;  4MCQ A;  3S9M A;  5AXI A;  3S9N A;  3VRQ A;  3PLF B;  3BHX A;  4OC1 A;  2B4J C;  4NGN A;  3PT1 A;  3RBU A;  4P4J A;  3ZNI A;  1B47 A;  3HMJ G;  3D7F A;  2VKZ G;  5F09 A;  3F9K C;  4NGR A;  4OC4 A;  2XEF A;  2PVW A;  4NGP A;  1YVH A;  1DE4 C;  4OME A;  4P4E A;  3FF3 A;  2C6P A;  3VRO A;  1CX8 A;  3IWW A;  2DLA A;  1WJT A;  5D29 A;  4P4D A;  4OC2 A;  1Z8L A;  4W9Y A;  4BPW B;  3D7H A;  2XPO A;  4JZ0 A;  2XEJ A;  3BUW B;  5HKZ A;  4OC0 A;  3SJE A;  2XPN A;  1Z9E A;  3BUN B;  3D7G A;  3BUM B;  2CIJ A;  2JBJ A;  2OOT A;  3D7D A;  3VRP A;  3BXM A;  4MCP A;  3HPG G;  4GPL B;  4P4F A;  3KAS A;  3PFV A;  1EO0 A;  4RR2 B;  2XPL A;  3U88 C;  4NGS A;  2JBK A;  3OAK A;  4P4I A;  4JYW A;  3VRR A;  2UV8 G;  3SJX A;  4MCR A;  3O8Z A;  3BUO B;  2XPP A;  4X3R A;  2C6G A;  4A4C A;  4P4B A;  1FBV A;  5HKW A;  3HPH E;  4P45 A;  3SJG A;  5HKY A;  2C6C A;  3VGO A;  5ELY A;  4MCS A;  4BPX B;  5F13 A;  3S9L A;  2Y1N A;  4NGM A;  3BI0 A;  4P44 A;  4BPU B;  2OR4 A;  2Y1M A;  3BUX B;  5J3X A;  2PVV A;  2CBL A;  3OB2 B;  3FED A;  3OP0 A;  3BI1 A;  4NGQ A;  4OC3 A;  2XEG A;  3OB1 B;  3SJF A;  3FEE A;  3NFQ A;  3VRN A;  4OC5 A;  2N3A B;  2XEI A;  4LQG A;  4BTF A;  3FEC A; 
#chains in the Genus database with same CATH homology
 3NFQ A;  3OAK A;  2XPN A;  1Z9E A;  1EO0 A;  3O8Z A;  3HPH E;  2XPL A;  2N3A B;  2XPO A;  2XPP A;  3F9K C;  3HPG G;  1WJT A;  2B4J C;  3U88 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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