4BPUB

Crystal structure of human primase in heterodimeric form, comprising pris and truncated pril lacking the c-terminal fe-s domain.
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
244
structure length
216
Chain Sequence
KLRLAGYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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connected with : NaN
molecule tags Transferase
source organism Homo sapiens
publication title Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
pubmed doi rcsb
molecule keywords DNA PRIMASE SMALL SUBUNIT
total genus 70
structure length 216
sequence length 244
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-05-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4bpuB00
4BPUB 4BPXB 4RR2B 4BPWB
chains in the Genus database with same CATH superfamily
4OC0A 4MCPA 4JYWA 1EO0A 3BI0A 4W9YA 2PVVA 4NGRA 4NGMA 3S9MA 3VGOA 3BUWB 1Z9EA 1YVHA 4P4BA 2C6GA 5F13A 2VKZG 5HKYA 2XEGA 5HKWA 3VRRA 3VRQA 4P4EA 1DE4C 3KASA 3D7FA 2CIJA 3HPHE 3PLFB 3D7DA 2JBJA 2OR4A 3HMJG 4P4FA 4P4IA 4A4CA 4BPXB 4GPLB 3SJXA 3D7HA 5J3XA 2UV8G 4NGSA 5ELYA 2Y1MA 3FEDA 2XPPA 3SJGA 3HPGG 4NGPA 3ZNIA 4JZ0A 3NFQA 3D7GA 4MCSA 2PVWA 4OMEA 4P4DA 3PFVA 4OC3A 3BUOB 1WJTA 2C6CA 3OP0A 3BI1A 3PT1A 1CX8A 3VROA 4P44A 2OOTA 4OC1A 2DLAA 3S9NA 3BXMA 2XPLA 3OB2B 2JBKA 4OC2A 1FBVA 4MCRA 2XEFA 4LQGA 1Z8LA 2B4JC 3BHXA 3U88C 1B47A 5BY0A 4BPUB 4NGTA 2XEIA 2XPNA 5D29A 2Y1NA 5AXIA 3OB1B 2C6PA 3BUMB 2XEJA 4NGNA 3RBUA 3S9LA 5HKZA 3SJFA 3BUNB 3F9KC 3IWWA 3OAKA 3FEEA 4NGQA 4A4BA 4OC5A 3VRPA 4P4JA 3FECA 4P45A 4RR2B 3FF3A 3BUXB 4BTFA 3SJEA 5F09A 2XPOA 3O8ZA 3VRNA 4BPWB 2CBLA 4X3RA 4OC4A 2N3AB 4MCQA
chains in the Genus database with same CATH topology
2UV8G 5F13A 2VKZG 5BY0A 4BPXB 3PT1A 4RR2B 4BPUB 4BPWB 2DLAA 3HMJG
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4BPU B;  4BPX B;  4RR2 B;  4BPW B; 
#chains in the Genus database with same CATH topology
 4OC0 A;  4MCP A;  4JYW A;  1EO0 A;  3BI0 A;  4W9Y A;  2PVV A;  4NGR A;  4NGM A;  3S9M A;  3VGO A;  3BUW B;  1Z9E A;  1YVH A;  4P4B A;  2C6G A;  5F13 A;  2VKZ G;  5HKY A;  2XEG A;  5HKW A;  3VRR A;  3VRQ A;  4P4E A;  1DE4 C;  3KAS A;  3D7F A;  2CIJ A;  3HPH E;  3PLF B;  3D7D A;  2JBJ A;  2OR4 A;  3HMJ G;  4P4F A;  4P4I A;  4A4C A;  4BPX B;  4GPL B;  3SJX A;  3D7H A;  5J3X A;  2UV8 G;  4NGS A;  5ELY A;  2Y1M A;  3FED A;  2XPP A;  3SJG A;  3HPG G;  4NGP A;  3ZNI A;  4JZ0 A;  3NFQ A;  3D7G A;  4MCS A;  2PVW A;  4OME A;  4P4D A;  3PFV A;  4OC3 A;  3BUO B;  1WJT A;  2C6C A;  3OP0 A;  3BI1 A;  3PT1 A;  1CX8 A;  3VRO A;  4P44 A;  2OOT A;  4OC1 A;  2DLA A;  3S9N A;  3BXM A;  2XPL A;  3OB2 B;  2JBK A;  4OC2 A;  1FBV A;  4MCR A;  2XEF A;  4LQG A;  1Z8L A;  2B4J C;  3BHX A;  3U88 C;  1B47 A;  5BY0 A;  4BPU B;  4NGT A;  2XEI A;  2XPN A;  5D29 A;  2Y1N A;  5AXI A;  3OB1 B;  2C6P A;  3BUM B;  2XEJ A;  4NGN A;  3RBU A;  3S9L A;  5HKZ A;  3SJF A;  3BUN B;  3F9K C;  3IWW A;  3OAK A;  3FEE A;  4NGQ A;  4A4B A;  4OC5 A;  3VRP A;  4P4J A;  3FEC A;  4P45 A;  4RR2 B;  3FF3 A;  3BUX B;  4BTF A;  3SJE A;  5F09 A;  2XPO A;  3O8Z A;  3VRN A;  4BPW B;  2CBL A;  4X3R A;  4OC4 A;  2N3A B;  4MCQ A; 
#chains in the Genus database with same CATH homology
 2UV8 G;  5F13 A;  2VKZ G;  5BY0 A;  4BPX B;  3PT1 A;  4RR2 B;  4BPU B;  4BPW B;  2DLA A;  3HMJ G;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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