4BPUB

Crystal structure of human primase in heterodimeric form, comprising pris and truncated pril lacking the c-terminal fe-s domain.
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
244
structure length
216
Chain Sequence
KLRLAGYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
pubmed doi rcsb
molecule keywords DNA PRIMASE SMALL SUBUNIT
molecule tags Transferase
source organism Homo sapiens
total genus 70
structure length 216
sequence length 244
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-05-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4bpuB00
4RR2B 4BPXB 4BPWB 4BPUB
chains in the Genus database with same CATH superfamily
1WJTA 2XEIA 4LQGA 4MCQA 2XEFA 4OC5A 1DE4C 2XPOA 3SJFA 4A4BA 2OR4A 3PT1A 4X3RA 2UV8G 2C6PA 5F13A 4P4IA 1Z9EA 3OP0A 3D7DA 4NGQA 4P4FA 5J3XA 4JZ0A 3S9MA 4BPUB 3OB2B 3HPGG 3BI1A 4NGPA 4OMEA 2B4JC 1Z8LA 4JYWA 1FBVA 3F9KC 3D7GA 3BUMB 1B47A 4OC3A 3RBUA 3VGOA 2Y1MA 2N3AB 1EO0A 3FEEA 5BY0A 3S9LA 5HKZA 4BPXB 3VRRA 3O8ZA 3IWWA 4NGSA 4BPWB 3BUOB 4NGMA 3BUWB 3VRNA 4OC4A 3OB1B 2PVWA 2VKZG 3D7FA 4A4CA 3PLFB 3FF3A 2C6CA 3SJGA 2XPLA 5HKYA 2JBKA 4P45A 5D29A 3NFQA 4P44A 3OAKA 4OC1A 3HMJG 3ZNIA 3HPHE 3VRPA 3SJXA 4P4EA 2PVVA 2CIJA 4W9YA 5AXIA 2OOTA 4NGTA 2C6GA 3VRQA 2CBLA 4MCRA 3FEDA 4NGNA 3VROA 3BI0A 4OC2A 4RR2B 1YVHA 3PFVA 3D7HA 2DLAA 3KASA 5F09A 3BUXB 2XPPA 2JBJA 1CX8A 5HKWA 3S9NA 4NGRA 3SJEA 3FECA 4MCPA 2Y1NA 3U88C 3BUNB 4MCSA 3BHXA 4P4JA 4P4BA 4BTFA 5ELYA 3BXMA 2XEJA 2XPNA 4OC0A 4P4DA 2XEGA 4GPLB
chains in the Genus database with same CATH topology
2UV8G 2DLAA 5F13A 5BY0A 3HMJG 2VKZG 4BPXB 4BPUB 4RR2B 4BPWB 3PT1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RR2 B;  4BPX B;  4BPW B;  4BPU B; 
#chains in the Genus database with same CATH topology
 1WJT A;  2XEI A;  4LQG A;  4MCQ A;  2XEF A;  4OC5 A;  1DE4 C;  2XPO A;  3SJF A;  4A4B A;  2OR4 A;  3PT1 A;  4X3R A;  2UV8 G;  2C6P A;  5F13 A;  4P4I A;  1Z9E A;  3OP0 A;  3D7D A;  4NGQ A;  4P4F A;  5J3X A;  4JZ0 A;  3S9M A;  4BPU B;  3OB2 B;  3HPG G;  3BI1 A;  4NGP A;  4OME A;  2B4J C;  1Z8L A;  4JYW A;  1FBV A;  3F9K C;  3D7G A;  3BUM B;  1B47 A;  4OC3 A;  3RBU A;  3VGO A;  2Y1M A;  2N3A B;  1EO0 A;  3FEE A;  5BY0 A;  3S9L A;  5HKZ A;  4BPX B;  3VRR A;  3O8Z A;  3IWW A;  4NGS A;  4BPW B;  3BUO B;  4NGM A;  3BUW B;  3VRN A;  4OC4 A;  3OB1 B;  2PVW A;  2VKZ G;  3D7F A;  4A4C A;  3PLF B;  3FF3 A;  2C6C A;  3SJG A;  2XPL A;  5HKY A;  2JBK A;  4P45 A;  5D29 A;  3NFQ A;  4P44 A;  3OAK A;  4OC1 A;  3HMJ G;  3ZNI A;  3HPH E;  3VRP A;  3SJX A;  4P4E A;  2PVV A;  2CIJ A;  4W9Y A;  5AXI A;  2OOT A;  4NGT A;  2C6G A;  3VRQ A;  2CBL A;  4MCR A;  3FED A;  4NGN A;  3VRO A;  3BI0 A;  4OC2 A;  4RR2 B;  1YVH A;  3PFV A;  3D7H A;  2DLA A;  3KAS A;  5F09 A;  3BUX B;  2XPP A;  2JBJ A;  1CX8 A;  5HKW A;  3S9N A;  4NGR A;  3SJE A;  3FEC A;  4MCP A;  2Y1N A;  3U88 C;  3BUN B;  4MCS A;  3BHX A;  4P4J A;  4P4B A;  4BTF A;  5ELY A;  3BXM A;  2XEJ A;  2XPN A;  4OC0 A;  4P4D A;  2XEG A;  4GPL B; 
#chains in the Genus database with same CATH homology
 2UV8 G;  2DLA A;  5F13 A;  5BY0 A;  3HMJ G;  2VKZ G;  4BPX B;  4BPU B;  4RR2 B;  4BPW B;  3PT1 A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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