4BPWB

Crystal structure of human primase bound to utp
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
243
structure length
219
Chain Sequence
LRLAGYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSIPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords DNA PRIMASE SMALL SUBUNIT
total genus 63
structure length 219
sequence length 243
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-05-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4bpwB00
4BPUB 4RR2B 4BPXB 4BPWB
chains in the Genus database with same CATH superfamily
5J3XA 4NGPA 3D7DA 2C6PA 4BPXB 4BPWB 3SJXA 3BUOB 2XEIA 3BI0A 3PLFB 3VRQA 3BI1A 4P44A 2XPPA 2JBKA 4A4BA 3D7HA 1Z9EA 3HMJG 2XPNA 5HKZA 4OMEA 1B47A 4P4EA 2UV8G 4OC1A 2C6GA 3FEEA 5F13A 3S9MA 3VROA 1WJTA 4NGSA 3VRPA 3KASA 2OOTA 3D7FA 3VRRA 5F09A 4P4BA 4MCSA 5ELYA 1YVHA 4OC2A 3NFQA 5HKYA 3U88C 2XEGA 4P4JA 4MCQA 4NGMA 1DE4C 4NGRA 1FBVA 2OR4A 1Z8LA 2B4JC 4JZ0A 3RBUA 3SJGA 3BUMB 4BPUB 3F9KC 4P4IA 3HPHE 4A4CA 4P45A 4OC3A 4P4DA 1CX8A 4NGNA 2JBJA 3D7GA 3PFVA 3FECA 3S9NA 2XPLA 4OC0A 3OP0A 2PVWA 3BUWB 5AXIA 4BTFA 2CIJA 3SJFA 3BXMA 3OB2B 3BUXB 3IWWA 2XPOA 3FF3A 4MCRA 3BHXA 2N3AB 3SJEA 3ZNIA 3HPGG 5BY0A 2C6CA 2Y1NA 4OC5A 4P4FA 4X3RA 4NGQA 2XEJA 2PVVA 1EO0A 4MCPA 2VKZG 3O8ZA 4NGTA 4LQGA 4JYWA 5D29A 3VGOA 3S9LA 4OC4A 4GPLB 3OB1B 2CBLA 4RR2B 3VRNA 3FEDA 2XEFA 2DLAA 3OAKA 5HKWA 4W9YA 3PT1A 2Y1MA 3BUNB
chains in the Genus database with same CATH topology
4BPUB 5BY0A 4BPWB 2DLAA 5F13A 3HMJG 4RR2B 4BPXB 2UV8G 2VKZG 3PT1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPU B;  4RR2 B;  4BPX B;  4BPW B; 
#chains in the Genus database with same CATH topology
 5J3X A;  4NGP A;  3D7D A;  2C6P A;  4BPX B;  4BPW B;  3SJX A;  3BUO B;  2XEI A;  3BI0 A;  3PLF B;  3VRQ A;  3BI1 A;  4P44 A;  2XPP A;  2JBK A;  4A4B A;  3D7H A;  1Z9E A;  3HMJ G;  2XPN A;  5HKZ A;  4OME A;  1B47 A;  4P4E A;  2UV8 G;  4OC1 A;  2C6G A;  3FEE A;  5F13 A;  3S9M A;  3VRO A;  1WJT A;  4NGS A;  3VRP A;  3KAS A;  2OOT A;  3D7F A;  3VRR A;  5F09 A;  4P4B A;  4MCS A;  5ELY A;  1YVH A;  4OC2 A;  3NFQ A;  5HKY A;  3U88 C;  2XEG A;  4P4J A;  4MCQ A;  4NGM A;  1DE4 C;  4NGR A;  1FBV A;  2OR4 A;  1Z8L A;  2B4J C;  4JZ0 A;  3RBU A;  3SJG A;  3BUM B;  4BPU B;  3F9K C;  4P4I A;  3HPH E;  4A4C A;  4P45 A;  4OC3 A;  4P4D A;  1CX8 A;  4NGN A;  2JBJ A;  3D7G A;  3PFV A;  3FEC A;  3S9N A;  2XPL A;  4OC0 A;  3OP0 A;  2PVW A;  3BUW B;  5AXI A;  4BTF A;  2CIJ A;  3SJF A;  3BXM A;  3OB2 B;  3BUX B;  3IWW A;  2XPO A;  3FF3 A;  4MCR A;  3BHX A;  2N3A B;  3SJE A;  3ZNI A;  3HPG G;  5BY0 A;  2C6C A;  2Y1N A;  4OC5 A;  4P4F A;  4X3R A;  4NGQ A;  2XEJ A;  2PVV A;  1EO0 A;  4MCP A;  2VKZ G;  3O8Z A;  4NGT A;  4LQG A;  4JYW A;  5D29 A;  3VGO A;  3S9L A;  4OC4 A;  4GPL B;  3OB1 B;  2CBL A;  4RR2 B;  3VRN A;  3FED A;  2XEF A;  2DLA A;  3OAK A;  5HKW A;  4W9Y A;  3PT1 A;  2Y1M A;  3BUN B; 
#chains in the Genus database with same CATH homology
 4BPU B;  5BY0 A;  4BPW B;  2DLA A;  5F13 A;  3HMJ G;  4RR2 B;  4BPX B;  2UV8 G;  2VKZ G;  3PT1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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