4BPXB

Crystal structure of human primase in complex with the primase- binding motif of dna polymerase alpha
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
217
structure length
181
Chain Sequence
ISLIEFENLAIDRVKLLKSVENLSKLESELRKLRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLDERLQPLLNHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords DNA PRIMASE SMALL SUBUNIT
total genus 50
structure length 181
sequence length 217
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-05-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4bpxB00
4BPXB 4BPWB 4RR2B 4BPUB
chains in the Genus database with same CATH superfamily
5BY0A 3SJFA 3BI0A 4GPLB 5HKYA 4P4BA 3VRPA 4W9YA 3SJXA 4BPXB 3PFVA 3FECA 2N3AB 2XPNA 3HPGG 3PT1A 4MCQA 3HPHE 3F9KC 4NGTA 5HKWA 2C6CA 4P4IA 5ELYA 4OC4A 4A4CA 4OC2A 3BUWB 4NGSA 3U88C 2CBLA 3FEEA 3S9MA 2JBJA 4P4DA 3O8ZA 2XPPA 4RR2B 3D7HA 3OP0A 4P45A 4JYWA 4P44A 4P4FA 4X3RA 5AXIA 3SJGA 3VRNA 1Z8LA 3BUOB 3FEDA 4NGMA 3PLFB 3KASA 3VGOA 2Y1MA 1WJTA 3VRRA 4MCPA 4OC0A 1DE4C 1CX8A 3IWWA 4NGNA 3BUMB 4OC3A 4BPWB 4A4BA 2VKZG 3D7GA 2Y1NA 5D29A 1B47A 3S9NA 3BHXA 2C6PA 3BXMA 3NFQA 2CIJA 1FBVA 4LQGA 4OC5A 2XEFA 5J3XA 4P4EA 2XPLA 3D7DA 3BUNB 2XEJA 3ZNIA 2B4JC 2JBKA 3VROA 4MCRA 3OB2B 2PVVA 2DLAA 3VRQA 2XEIA 4BTFA 3BUXB 2XEGA 5F09A 3OB1B 4MCSA 3D7FA 3RBUA 1YVHA 2C6GA 1EO0A 4NGRA 2PVWA 2UV8G 3HMJG 1Z9EA 5F13A 2OR4A 4JZ0A 4NGQA 4NGPA 4P4JA 3BI1A 3FF3A 5HKZA 2OOTA 2XPOA 4BPUB 4OC1A 4OMEA 3SJEA 3S9LA 3OAKA
chains in the Genus database with same CATH topology
4BPUB 5F13A 5BY0A 3HMJG 3PT1A 2DLAA 4BPWB 2VKZG 4BPXB 4RR2B 2UV8G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPX B;  4BPW B;  4RR2 B;  4BPU B; 
#chains in the Genus database with same CATH topology
 5BY0 A;  3SJF A;  3BI0 A;  4GPL B;  5HKY A;  4P4B A;  3VRP A;  4W9Y A;  3SJX A;  4BPX B;  3PFV A;  3FEC A;  2N3A B;  2XPN A;  3HPG G;  3PT1 A;  4MCQ A;  3HPH E;  3F9K C;  4NGT A;  5HKW A;  2C6C A;  4P4I A;  5ELY A;  4OC4 A;  4A4C A;  4OC2 A;  3BUW B;  4NGS A;  3U88 C;  2CBL A;  3FEE A;  3S9M A;  2JBJ A;  4P4D A;  3O8Z A;  2XPP A;  4RR2 B;  3D7H A;  3OP0 A;  4P45 A;  4JYW A;  4P44 A;  4P4F A;  4X3R A;  5AXI A;  3SJG A;  3VRN A;  1Z8L A;  3BUO B;  3FED A;  4NGM A;  3PLF B;  3KAS A;  3VGO A;  2Y1M A;  1WJT A;  3VRR A;  4MCP A;  4OC0 A;  1DE4 C;  1CX8 A;  3IWW A;  4NGN A;  3BUM B;  4OC3 A;  4BPW B;  4A4B A;  2VKZ G;  3D7G A;  2Y1N A;  5D29 A;  1B47 A;  3S9N A;  3BHX A;  2C6P A;  3BXM A;  3NFQ A;  2CIJ A;  1FBV A;  4LQG A;  4OC5 A;  2XEF A;  5J3X A;  4P4E A;  2XPL A;  3D7D A;  3BUN B;  2XEJ A;  3ZNI A;  2B4J C;  2JBK A;  3VRO A;  4MCR A;  3OB2 B;  2PVV A;  2DLA A;  3VRQ A;  2XEI A;  4BTF A;  3BUX B;  2XEG A;  5F09 A;  3OB1 B;  4MCS A;  3D7F A;  3RBU A;  1YVH A;  2C6G A;  1EO0 A;  4NGR A;  2PVW A;  2UV8 G;  3HMJ G;  1Z9E A;  5F13 A;  2OR4 A;  4JZ0 A;  4NGQ A;  4NGP A;  4P4J A;  3BI1 A;  3FF3 A;  5HKZ A;  2OOT A;  2XPO A;  4BPU B;  4OC1 A;  4OME A;  3SJE A;  3S9L A;  3OAK A; 
#chains in the Genus database with same CATH homology
 4BPU B;  5F13 A;  5BY0 A;  3HMJ G;  3PT1 A;  2DLA A;  4BPW B;  2VKZ G;  4BPX B;  4RR2 B;  2UV8 G; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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