4BPXB

Crystal structure of human primase in complex with the primase- binding motif of dna polymerase alpha
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
217
structure length
181
Chain Sequence
ISLIEFENLAIDRVKLLKSVENLSKLESELRKLRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLDERLQPLLNHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
pubmed doi rcsb
molecule keywords DNA PRIMASE SMALL SUBUNIT
molecule tags Transferase
source organism Homo sapiens
total genus 50
structure length 181
sequence length 217
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-05-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4bpxB00
4BPXB 4BPUB 4RR2B 4BPWB
chains in the Genus database with same CATH superfamily
3HPHE 3FECA 4MCQA 3S9NA 3OB2B 2OR4A 3BUNB 4P44A 3FF3A 4BTFA 3U88C 3SJEA 2N3AB 3IWWA 3PT1A 3VRQA 4A4CA 1CX8A 3HMJG 3SJGA 4MCRA 4OC2A 2UV8G 2XEGA 2XPNA 3BHXA 3BXMA 4BPXB 4NGTA 2XPOA 4OC1A 2DLAA 3VRPA 4P4DA 3PLFB 4JYWA 3VRNA 3PFVA 4OC0A 2C6PA 5BY0A 1EO0A 4P4IA 2CBLA 3HPGG 5F13A 3S9MA 2XPPA 2XEIA 4NGSA 1Z8LA 1DE4C 1FBVA 3BI0A 4NGMA 4NGRA 3O8ZA 1WJTA 5HKYA 3D7HA 3D7GA 3BI1A 3OAKA 3VGOA 3ZNIA 4OC3A 3BUMB 4OC5A 4OMEA 3D7FA 2XPLA 4P4FA 2Y1MA 3RBUA 4W9YA 1B47A 4A4BA 3SJXA 4NGQA 4GPLB 4X3RA 3NFQA 3BUOB 3S9LA 4P4EA 4OC4A 4MCPA 5AXIA 3BUXB 2Y1NA 2XEFA 3OP0A 4MCSA 5ELYA 2C6CA 3D7DA 5D29A 5HKWA 3OB1B 2VKZG 5F09A 2B4JC 1Z9EA 4BPUB 2CIJA 2PVWA 3KASA 2OOTA 2PVVA 3FEDA 4P4JA 3SJFA 3FEEA 4NGPA 4NGNA 5J3XA 4P4BA 4BPWB 2XEJA 1YVHA 4P45A 3BUWB 5HKZA 3VRRA 2JBKA 4JZ0A 2JBJA 4RR2B 2C6GA 3F9KC 3VROA 4LQGA
chains in the Genus database with same CATH topology
3PT1A 5F13A 4BPUB 2VKZG 4RR2B 3HMJG 4BPXB 5BY0A 4BPWB 2UV8G 2DLAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPX B;  4BPU B;  4RR2 B;  4BPW B; 
#chains in the Genus database with same CATH topology
 3HPH E;  3FEC A;  4MCQ A;  3S9N A;  3OB2 B;  2OR4 A;  3BUN B;  4P44 A;  3FF3 A;  4BTF A;  3U88 C;  3SJE A;  2N3A B;  3IWW A;  3PT1 A;  3VRQ A;  4A4C A;  1CX8 A;  3HMJ G;  3SJG A;  4MCR A;  4OC2 A;  2UV8 G;  2XEG A;  2XPN A;  3BHX A;  3BXM A;  4BPX B;  4NGT A;  2XPO A;  4OC1 A;  2DLA A;  3VRP A;  4P4D A;  3PLF B;  4JYW A;  3VRN A;  3PFV A;  4OC0 A;  2C6P A;  5BY0 A;  1EO0 A;  4P4I A;  2CBL A;  3HPG G;  5F13 A;  3S9M A;  2XPP A;  2XEI A;  4NGS A;  1Z8L A;  1DE4 C;  1FBV A;  3BI0 A;  4NGM A;  4NGR A;  3O8Z A;  1WJT A;  5HKY A;  3D7H A;  3D7G A;  3BI1 A;  3OAK A;  3VGO A;  3ZNI A;  4OC3 A;  3BUM B;  4OC5 A;  4OME A;  3D7F A;  2XPL A;  4P4F A;  2Y1M A;  3RBU A;  4W9Y A;  1B47 A;  4A4B A;  3SJX A;  4NGQ A;  4GPL B;  4X3R A;  3NFQ A;  3BUO B;  3S9L A;  4P4E A;  4OC4 A;  4MCP A;  5AXI A;  3BUX B;  2Y1N A;  2XEF A;  3OP0 A;  4MCS A;  5ELY A;  2C6C A;  3D7D A;  5D29 A;  5HKW A;  3OB1 B;  2VKZ G;  5F09 A;  2B4J C;  1Z9E A;  4BPU B;  2CIJ A;  2PVW A;  3KAS A;  2OOT A;  2PVV A;  3FED A;  4P4J A;  3SJF A;  3FEE A;  4NGP A;  4NGN A;  5J3X A;  4P4B A;  4BPW B;  2XEJ A;  1YVH A;  4P45 A;  3BUW B;  5HKZ A;  3VRR A;  2JBK A;  4JZ0 A;  2JBJ A;  4RR2 B;  2C6G A;  3F9K C;  3VRO A;  4LQG A; 
#chains in the Genus database with same CATH homology
 3PT1 A;  5F13 A;  4BPU B;  2VKZ G;  4RR2 B;  3HMJ G;  4BPX B;  5BY0 A;  4BPW B;  2UV8 G;  2DLA A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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