4RR2B

Crystal structure of human primase
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
224
structure length
213
Chain Sequence
FYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the human primase.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords DNA primase small subunit
total genus 67
structure length 213
sequence length 224
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2014-11-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF04104 DNA_primase_lrg Eukaryotic and archaeal DNA primase, large subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4rr2B00
4BPWB 4RR2B 4BPXB 4BPUB
chains in the Genus database with same CATH superfamily
2JBKA 3PT1A 2CIJA 3IWWA 3BHXA 2XEFA 4A4BA 3BUOB 3FF3A 3KASA 2XEGA 3VGOA 4P4EA 2Y1MA 2XEIA 5J3XA 5HKYA 4P44A 2XPNA 4BPUB 5HKZA 3BUXB 4GPLB 2XPLA 5F09A 3OB2B 4P45A 4OC0A 4P4BA 1Z9EA 1FBVA 4MCRA 4NGRA 2XEJA 3D7FA 3HMJG 5ELYA 3SJXA 3OP0A 5AXIA 4P4DA 4BPXB 4LQGA 3BUNB 3SJEA 3SJFA 4MCPA 2C6GA 1B47A 4OC1A 4RR2B 2VKZG 3PLFB 3SJGA 5F13A 3FEEA 1Z8LA 3BI0A 3D7HA 2DLAA 3VRRA 1EO0A 3D7GA 4OC4A 3HPGG 1WJTA 3S9LA 3D7DA 2OOTA 3PFVA 3NFQA 3RBUA 4JYWA 4JZ0A 3BI1A 2C6PA 3VROA 4P4FA 4NGNA 4P4JA 4P4IA 4NGPA 2Y1NA 2XPPA 2OR4A 3HPHE 4OC5A 3S9NA 3U88C 3OB1B 2N3AB 4OC2A 4BPWB 4BTFA 1DE4C 3BUWB 3FECA 2PVVA 3O8ZA 5D29A 3VRNA 2B4JC 3VRQA 4NGTA 4NGQA 1YVHA 4NGMA 3OAKA 1CX8A 3FEDA 5HKWA 3ZNIA 4MCQA 4OC3A 4X3RA 3F9KC 2JBJA 4MCSA 4W9YA 3BUMB 3VRPA 2CBLA 5BY0A 4OMEA 2XPOA 4A4CA 3BXMA 3S9MA 2UV8G 2C6CA 4NGSA 2PVWA
chains in the Genus database with same CATH topology
3PT1A 4BPUB 5F13A 3HMJG 5BY0A 2UV8G 4BPWB 4RR2B 2VKZG 4BPXB 2DLAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPW B;  4RR2 B;  4BPX B;  4BPU B; 
#chains in the Genus database with same CATH topology
 2JBK A;  3PT1 A;  2CIJ A;  3IWW A;  3BHX A;  2XEF A;  4A4B A;  3BUO B;  3FF3 A;  3KAS A;  2XEG A;  3VGO A;  4P4E A;  2Y1M A;  2XEI A;  5J3X A;  5HKY A;  4P44 A;  2XPN A;  4BPU B;  5HKZ A;  3BUX B;  4GPL B;  2XPL A;  5F09 A;  3OB2 B;  4P45 A;  4OC0 A;  4P4B A;  1Z9E A;  1FBV A;  4MCR A;  4NGR A;  2XEJ A;  3D7F A;  3HMJ G;  5ELY A;  3SJX A;  3OP0 A;  5AXI A;  4P4D A;  4BPX B;  4LQG A;  3BUN B;  3SJE A;  3SJF A;  4MCP A;  2C6G A;  1B47 A;  4OC1 A;  4RR2 B;  2VKZ G;  3PLF B;  3SJG A;  5F13 A;  3FEE A;  1Z8L A;  3BI0 A;  3D7H A;  2DLA A;  3VRR A;  1EO0 A;  3D7G A;  4OC4 A;  3HPG G;  1WJT A;  3S9L A;  3D7D A;  2OOT A;  3PFV A;  3NFQ A;  3RBU A;  4JYW A;  4JZ0 A;  3BI1 A;  2C6P A;  3VRO A;  4P4F A;  4NGN A;  4P4J A;  4P4I A;  4NGP A;  2Y1N A;  2XPP A;  2OR4 A;  3HPH E;  4OC5 A;  3S9N A;  3U88 C;  3OB1 B;  2N3A B;  4OC2 A;  4BPW B;  4BTF A;  1DE4 C;  3BUW B;  3FEC A;  2PVV A;  3O8Z A;  5D29 A;  3VRN A;  2B4J C;  3VRQ A;  4NGT A;  4NGQ A;  1YVH A;  4NGM A;  3OAK A;  1CX8 A;  3FED A;  5HKW A;  3ZNI A;  4MCQ A;  4OC3 A;  4X3R A;  3F9K C;  2JBJ A;  4MCS A;  4W9Y A;  3BUM B;  3VRP A;  2CBL A;  5BY0 A;  4OME A;  2XPO A;  4A4C A;  3BXM A;  3S9M A;  2UV8 G;  2C6C A;  4NGS A;  2PVW A; 
#chains in the Genus database with same CATH homology
 3PT1 A;  4BPU B;  5F13 A;  3HMJ G;  5BY0 A;  2UV8 G;  4BPW B;  4RR2 B;  2VKZ G;  4BPX B;  2DLA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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