4RR2B

Crystal structure of human primase
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
224
structure length
213
Chain Sequence
FYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the human primase.
pubmed doi rcsb
molecule keywords DNA primase small subunit
molecule tags Transferase
source organism Homo sapiens
total genus 67
structure length 213
sequence length 224
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2014-11-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF04104 DNA_primase_lrg Eukaryotic and archaeal DNA primase, large subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4rr2B00
4BPWB 4RR2B 4BPXB 4BPUB
chains in the Genus database with same CATH superfamily
4MCPA 4NGPA 3ZNIA 3VROA 4NGMA 3BI0A 1Z9EA 3SJFA 3OB2B 3SJXA 5F09A 3BHXA 2OR4A 4BPUB 3BUNB 3F9KC 2B4JC 4NGQA 3BXMA 3OAKA 3VRQA 2JBJA 4P4IA 4W9YA 2CIJA 3FEEA 3FEDA 3VRRA 4P4FA 4OC3A 4P4BA 2Y1MA 2UV8G 2C6GA 3OP0A 2XEIA 3HPGG 4BPWB 1YVHA 4P4JA 2XEJA 4X3RA 3BUOB 3D7HA 3VRPA 3PT1A 4JZ0A 1WJTA 3PFVA 2XPPA 3S9LA 3RBUA 4MCRA 1FBVA 1EO0A 3BI1A 4A4BA 4OC0A 5ELYA 1B47A 3D7GA 3KASA 3FECA 4OC1A 4NGRA 4P4EA 2XPNA 1DE4C 3OB1B 4NGSA 3SJEA 4BPXB 2DLAA 4NGNA 1CX8A 5HKZA 5HKWA 3S9NA 5HKYA 2VKZG 3O8ZA 3VRNA 4BTFA 4NGTA 3D7FA 3SJGA 4OC5A 1Z8LA 4JYWA 3D7DA 4LQGA 3HMJG 2XEFA 5F13A 2C6PA 4OMEA 2OOTA 4P44A 5BY0A 3VGOA 3BUWB 3IWWA 4OC2A 2XPOA 3NFQA 2Y1NA 2JBKA 4MCSA 2PVWA 2XEGA 4MCQA 3U88C 4OC4A 2C6CA 3S9MA 2XPLA 4GPLB 3BUXB 4RR2B 3PLFB 4P4DA 4A4CA 5D29A 5J3XA 3HPHE 2CBLA 3FF3A 4P45A 3BUMB 2N3AB 2PVVA 5AXIA
chains in the Genus database with same CATH topology
3PT1A 5F13A 2UV8G 4BPXB 2VKZG 4BPWB 2DLAA 5BY0A 4BPUB 3HMJG 4RR2B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPW B;  4RR2 B;  4BPX B;  4BPU B; 
#chains in the Genus database with same CATH topology
 4MCP A;  4NGP A;  3ZNI A;  3VRO A;  4NGM A;  3BI0 A;  1Z9E A;  3SJF A;  3OB2 B;  3SJX A;  5F09 A;  3BHX A;  2OR4 A;  4BPU B;  3BUN B;  3F9K C;  2B4J C;  4NGQ A;  3BXM A;  3OAK A;  3VRQ A;  2JBJ A;  4P4I A;  4W9Y A;  2CIJ A;  3FEE A;  3FED A;  3VRR A;  4P4F A;  4OC3 A;  4P4B A;  2Y1M A;  2UV8 G;  2C6G A;  3OP0 A;  2XEI A;  3HPG G;  4BPW B;  1YVH A;  4P4J A;  2XEJ A;  4X3R A;  3BUO B;  3D7H A;  3VRP A;  3PT1 A;  4JZ0 A;  1WJT A;  3PFV A;  2XPP A;  3S9L A;  3RBU A;  4MCR A;  1FBV A;  1EO0 A;  3BI1 A;  4A4B A;  4OC0 A;  5ELY A;  1B47 A;  3D7G A;  3KAS A;  3FEC A;  4OC1 A;  4NGR A;  4P4E A;  2XPN A;  1DE4 C;  3OB1 B;  4NGS A;  3SJE A;  4BPX B;  2DLA A;  4NGN A;  1CX8 A;  5HKZ A;  5HKW A;  3S9N A;  5HKY A;  2VKZ G;  3O8Z A;  3VRN A;  4BTF A;  4NGT A;  3D7F A;  3SJG A;  4OC5 A;  1Z8L A;  4JYW A;  3D7D A;  4LQG A;  3HMJ G;  2XEF A;  5F13 A;  2C6P A;  4OME A;  2OOT A;  4P44 A;  5BY0 A;  3VGO A;  3BUW B;  3IWW A;  4OC2 A;  2XPO A;  3NFQ A;  2Y1N A;  2JBK A;  4MCS A;  2PVW A;  2XEG A;  4MCQ A;  3U88 C;  4OC4 A;  2C6C A;  3S9M A;  2XPL A;  4GPL B;  3BUX B;  4RR2 B;  3PLF B;  4P4D A;  4A4C A;  5D29 A;  5J3X A;  3HPH E;  2CBL A;  3FF3 A;  4P45 A;  3BUM B;  2N3A B;  2PVV A;  5AXI A; 
#chains in the Genus database with same CATH homology
 3PT1 A;  5F13 A;  2UV8 G;  4BPX B;  2VKZ G;  4BPW B;  2DLA A;  5BY0 A;  4BPU B;  3HMJ G;  4RR2 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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