4JA3A

Partially occluded inward open conformation of the xylose transporter xyle from e. coli
Total Genus 174
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
174
sequence length
458
structure length
426
Chain Sequence
SYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVAPQNLSESAANSLLGFCVASALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGSAWPELGFTSINPDNTVPVYLAGYVPEFVIYRIIGGIGVGLASMLSPMYIAELAPAHIRGKLVSFNQFAIIFGQLLVYCVNYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLYTVPESPRWLMSRGKQEQAEGILRKIMGNTLATQAVQEIKHSLDHGRGVIVIGVMLSIFQQFVGINVVLYYAPEVSTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKPLQIIGALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSWGPVCWVLLSEALAIAVAAQWLANYFVSWTFPMMDKNSHNGFSYWIYGCMGVLAALFMWKFVPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords D-xylose-proton symporter
total genus 174
structure length 426
sequence length 458
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-02-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00083 Sugar_tr Sugar (and other) transporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.90 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ja3A02
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4ja3A01
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4ja3A03
3O7PA 4IU8A 4QIQA 4UVMA 4IKVA 4OAAA 4D2BA 4YB9D 5EQGA 4GC0A 4J05A 4D2CA 4IKXA 5GXBA 4GBYA 2Y5YA 5D58A 1PW4A 4ZW9A 4IKZA 5EQIA 5D59A 4OH3A 2CFPA 4TPGA 2V8NA 4TPHA 4LEPA 2CFQA 4ZWBA 5C65A 4GBZA 4XNJA 2XUTA 5A2OA 4JA3A 5EQHA 4XNIA 4ZWCA 4YBQA 4U4VA 4IU9A 4JREA 4W6VA 4TPJA 3O7QA 4PYPA 4D2DA 4JR9A 4APSA 1PV6A 3WDOA 5A2NA 4U4WA 4U4TA 4Q65A 5D6KA 1PV7A 4LDSA 4IKYA 4ZYRA 4IKWA
chains in the Genus database with same CATH superfamily
1IS7A 2Q7NB 3H0GD 3BPOA 4IKZA 1IK0A 2B8UA 4A93D 2CYKA 3PO3D 1IS8A 4QIQA 5IYDD 4NE5B 3D87A 5D22A 4A3LD 1PVHB 5D58A 5C3ED 2JA8D 4PS4A 1PGRA 3NCEA 1WM9A 2LMSA 1RFBA 4APSA 3N0PA 4U4TA 4Q65A 5D71A 3I4ND 1EERA 1RHGA 4EXPA 4A3FD 5LQBA 3HOXD 1HUWA 3QB1A 3QWRB 2Y5YA 2PN0A 1PW4A 1HWHA 2D9QA 1TFEA 1BGEA 1ITMA 3UEZE 4GBZA 1B5LA 2GMFA 4JREA 4W6VA 1HZIA 1IRLA 3LW5K 3O7QA 4PYPA 4JR9A 2Q98A 4IKWA 1WU3I 5C7XA 2WSFG 1Z7CA 3BMBA 3EJJA 3LB6B 5IYCD 4A3JD 1EL6A 1AX8A 3FKID 3D85C 4CNIC 4IU9A 1RCBA 4TPJA 4O9HA 1J7VL 5DMZA 3DUHC 1Y14A 2E9WC 4IU8A 1EMRA 1Y6KL 3UF5A 4DKCA 5TS9A 2LAGA 1Y1WD 4BY7D 4NEMA 3BPLA 2WSEG 1BGCA 1FYHA 4EXNA 1HWGA 3QAZA 4D2DA 1A7MA 2B63D 1INRA 1PY2A 5D72A 1M4CA 4OH3A 4XNJA 4XNIA 1M47A 1WUQA 2IL6A 1M49A 1NBPA 1LQSL 1P9MB 3WDOA 5D6KA 4O6KA 1WCMD 2B90A 1PV7A 3L5XA 4YPGC 4UVMA 1HULA 1EFUB 4IKVA 4D2CA 2OQPA 2R92D 4A3ID 1M48A 5C65A 3NCFA 5A2OA 1HGUA 4WRLB 4Q7JA 4YBQA 1CNT1 4U4WA 3B0BC 2O6IA 1V7NV 2PSMA 4NN6A 1SCFA 4J05A 1CSGA 4GBYA 1BBNA 4I77Z 2CFPA 4TPGA 4TPHA 2CFQA 2O27A 4BBRD 2VUMD 3SE3B 1A8RA 2D48A 4BBSD 3OG6A 4A3GD 4DKDA 5C4XD 4E45B 1JLIA 4YDYI 2XQBA 4LRLA 4NN5A 1N3RA 2WSFK 1Y6NL 2ILKA 4E44B 4DU6A 5D59A 5FLMD 3INKC 5L6YC 1M4BA 1D9GA 4ZWCA 1FB1A 2C35A 1D9CA 5FUCA 4RS1A 5IYBD 4R8QA 1HIJA 3BPNA 4A3MD 2R93D 3B5KA 4DKEA 2V8NA 1KF9A 4A3ED 1GTPA 2WSEK 1QVNA 4A3BD 2JA5D 4DRBJ 2L3OA 4ZF7A 1BP3A 4FA8E 1ITIA 2Z3QA 2WSCG 1WURA 1ILKA 4NI7A 4IKYA 1N3TA 1BUYA 4YB9D 3HOZD 2B91A 4DRAE 2KR1A 3NPZA 1ITLA 1BGDA 3VEJA 1IL6A 1RW5A 3WCYI 3L5WI 4NI9A 5E4EA 3BESL 1PW6A 3UF2A 1YKBA 3AYHA 4ZWBA 5D28B 3HHCA 4YUEC 2XUTA 3MZGA 1ETEA 4MHLA 3OQ3A 1CD9A 3HMXB 3D48P 3DI3A 3HHRA 4OAAA 5GXBA 3QT2C 1AXIA 4ZS7A 4BY1D 1ITFA 3G9VB 3S9DA 4LEPA 4NKQC 5D70A 2LNZA 1HIKA 4NEJA 3G6DA 2O01G 2HYMB 1F45B 2LO0A 1Y6ML 1N1FA 4GRWA 1IJZA 4A3KD 4Z5RD 1I1RB 1A22A 4LDSA 3HOUD 3QB7A 3NCCA 1VLKA 3TGXB 4IKXA 4BXXD 3PIWA 5EQIA 3H3VE 4J4LC 2O26A 1CN4C 3DGCL 5KNHI 3N06A 4YQXA 1EKUA 1A9CA 1GNCA 3PO2D 1Z92A 3HOYD 4ZYRA 3HOWD 1LK3A 3I4MD 4A3DD 2H24A 4GC0A 3Q1SI 3UX9A 5IP9D 1GA3A 1V7MV 4NN7A 3OG4A 1Y1VD 1FBXA 3LB6A 5EQHA 2KZ1A 3VA2A 2JA7D 4NE6B 1ALUA 4A3CD 3LW5G 5A2NA 1PV6A 1AU1A 5IP7D 1LKIA 2B8XA 2Z3RA 3SE4B 1M4RA 2P11A 1F6FA 1M4AA 4GS7A 2JA6D 2B5IA 2INTA 4U4VA 1EVSA 4DKFA 2WSCK 3DLQI 2B8YA 4QPMA 3O7PA 2ERJD 2L3YA 4NE3B 3EW3A 4D2BA 3DI2A 5EQGA 1IARA 4DOHA 4ZW9A 1CYLA 1BCNA 1N3SA 1AIPC 5FHXA 1FG9A 4JA3A 3NCBA 1WPLA 2B8ZA 5C44D 3HOVD 2Q14A 3IRHA 2R7ZD 1EXZA 3PIVA 4X51A
chains in the Genus database with same CATH topology
1IS7A 4IU8A 1N3RA 4IKXA 4E44B 4IKZA 5EQIA 4DU6A 5D59A 4ZWCA 1FB1A 1A9CA 4D2DA 4ZYRA 4R8QA 1IS8A 4QIQA 4NE5B 4GC0A 5D58A 4OH3A 2V8NA 1GTPA 4XNJA 1FBXA 1WM9A 4DRBJ 5EQHA 4XNIA 1WUQA 4NE6B 4APSA 5A2NA 1PV6A 3WDOA 1WURA 5D6KA 4U4TA 4Q65A 1PV7A 4IKYA 1N3TA 4YB9D 4UVMA 4IKVA 1EFUB 4D2CA 4DRAE 2KR1A 3VEJA 2Y5YA 2PN0A 1PW4A 1TFEA 2P11A 4ZWBA 5C65A 4GBZA 2XUTA 5A2OA 4Q7JA 4YBQA 4U4VA 4JREA 4W6VA 3O7QA 4PYPA 4JR9A 4U4WA 3B0BC 4IKWA 4QPMA 3O7PA 4NE3B 4OAAA 4D2BA 5EQGA 4J05A 5GXBA 4GBYA 3BMBA 4ZW9A 2CFPA 4TPGA 1N3SA 1AIPC 4LEPA 4TPHA 2LNZA 2CFQA 1EL6A 1A8RA 4JA3A 1WPLA 2LO0A 4IU9A 4TPJA 5DMZA 4E45B 4LDSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3O7P A;  4IU8 A;  4QIQ A;  4UVM A;  4IKV A;  4OAA A;  4D2B A;  4YB9 D;  5EQG A;  4GC0 A;  4J05 A;  4D2C A;  4IKX A;  5GXB A;  4GBY A;  2Y5Y A;  5D58 A;  1PW4 A;  4ZW9 A;  4IKZ A;  5EQI A;  5D59 A;  4OH3 A;  2CFP A;  4TPG A;  2V8N A;  4TPH A;  4LEP A;  2CFQ A;  4ZWB A;  5C65 A;  4GBZ A;  4XNJ A;  2XUT A;  5A2O A;  4JA3 A;  5EQH A;  4XNI A;  4ZWC A;  4YBQ A;  4U4V A;  4IU9 A;  4JRE A;  4W6V A;  4TPJ A;  3O7Q A;  4PYP A;  4D2D A;  4JR9 A;  4APS A;  1PV6 A;  3WDO A;  5A2N A;  4U4W A;  4U4T A;  4Q65 A;  5D6K A;  1PV7 A;  4LDS A;  4IKY A;  4ZYR A;  4IKW A; 
#chains in the Genus database with same CATH topology
 1IS7 A;  2Q7N B;  3H0G D;  3BPO A;  4IKZ A;  1IK0 A;  2B8U A;  4A93 D;  2CYK A;  3PO3 D;  1IS8 A;  4QIQ A;  5IYD D;  4NE5 B;  3D87 A;  5D22 A;  4A3L D;  1PVH B;  5D58 A;  5C3E D;  2JA8 D;  4PS4 A;  1PGR A;  3NCE A;  1WM9 A;  2LMS A;  1RFB A;  4APS A;  3N0P A;  4U4T A;  4Q65 A;  5D71 A;  3I4N D;  1EER A;  1RHG A;  4EXP A;  4A3F D;  5LQB A;  3HOX D;  1HUW A;  3QB1 A;  3QWR B;  2Y5Y A;  2PN0 A;  1PW4 A;  1HWH A;  2D9Q A;  1TFE A;  1BGE A;  1ITM A;  3UEZ E;  4GBZ A;  1B5L A;  2GMF A;  4JRE A;  4W6V A;  1HZI A;  1IRL A;  3LW5 K;  3O7Q A;  4PYP A;  4JR9 A;  2Q98 A;  4IKW A;  1WU3 I;  5C7X A;  2WSF G;  1Z7C A;  3BMB A;  3EJJ A;  3LB6 B;  5IYC D;  4A3J D;  1EL6 A;  1AX8 A;  3FKI D;  3D85 C;  4CNI C;  4IU9 A;  1RCB A;  4TPJ A;  4O9H A;  1J7V L;  5DMZ A;  3DUH C;  1Y14 A;  2E9W C;  4IU8 A;  1EMR A;  1Y6K L;  3UF5 A;  4DKC A;  5TS9 A;  2LAG A;  1Y1W D;  4BY7 D;  4NEM A;  3BPL A;  2WSE G;  1BGC A;  1FYH A;  4EXN A;  1HWG A;  3QAZ A;  4D2D A;  1A7M A;  2B63 D;  1INR A;  1PY2 A;  5D72 A;  1M4C A;  4OH3 A;  4XNJ A;  4XNI A;  1M47 A;  1WUQ A;  2IL6 A;  1M49 A;  1NBP A;  1LQS L;  1P9M B;  3WDO A;  5D6K A;  4O6K A;  1WCM D;  2B90 A;  1PV7 A;  3L5X A;  4YPG C;  4UVM A;  1HUL A;  1EFU B;  4IKV A;  4D2C A;  2OQP A;  2R92 D;  4A3I D;  1M48 A;  5C65 A;  3NCF A;  5A2O A;  1HGU A;  4WRL B;  4Q7J A;  4YBQ A;  1CNT 1;  4U4W A;  3B0B C;  2O6I A;  1V7N V;  2PSM A;  4NN6 A;  1SCF A;  4J05 A;  1CSG A;  4GBY A;  1BBN A;  4I77 Z;  2CFP A;  4TPG A;  4TPH A;  2CFQ A;  2O27 A;  4BBR D;  2VUM D;  3SE3 B;  1A8R A;  2D48 A;  4BBS D;  3OG6 A;  4A3G D;  4DKD A;  5C4X D;  4E45 B;  1JLI A;  4YDY I;  2XQB A;  4LRL A;  4NN5 A;  1N3R A;  2WSF K;  1Y6N L;  2ILK A;  4E44 B;  4DU6 A;  5D59 A;  5FLM D;  3INK C;  5L6Y C;  1M4B A;  1D9G A;  4ZWC A;  1FB1 A;  2C35 A;  1D9C A;  5FUC A;  4RS1 A;  5IYB D;  4R8Q A;  1HIJ A;  3BPN A;  4A3M D;  2R93 D;  3B5K A;  4DKE A;  2V8N A;  1KF9 A;  4A3E D;  1GTP A;  2WSE K;  1QVN A;  4A3B D;  2JA5 D;  4DRB J;  2L3O A;  4ZF7 A;  1BP3 A;  4FA8 E;  1ITI A;  2Z3Q A;  2WSC G;  1WUR A;  1ILK A;  4NI7 A;  4IKY A;  1N3T A;  1BUY A;  4YB9 D;  3HOZ D;  2B91 A;  4DRA E;  2KR1 A;  3NPZ A;  1ITL A;  1BGD A;  3VEJ A;  1IL6 A;  1RW5 A;  3WCY I;  3L5W I;  4NI9 A;  5E4E A;  3BES L;  1PW6 A;  3UF2 A;  1YKB A;  3AYH A;  4ZWB A;  5D28 B;  3HHC A;  4YUE C;  2XUT A;  3MZG A;  1ETE A;  4MHL A;  3OQ3 A;  1CD9 A;  3HMX B;  3D48 P;  3DI3 A;  3HHR A;  4OAA A;  5GXB A;  3QT2 C;  1AXI A;  4ZS7 A;  4BY1 D;  1ITF A;  3G9V B;  3S9D A;  4LEP A;  4NKQ C;  5D70 A;  2LNZ A;  1HIK A;  4NEJ A;  3G6D A;  2O01 G;  2HYM B;  1F45 B;  2LO0 A;  1Y6M L;  1N1F A;  4GRW A;  1IJZ A;  4A3K D;  4Z5R D;  1I1R B;  1A22 A;  4LDS A;  3HOU D;  3QB7 A;  3NCC A;  1VLK A;  3TGX B;  4IKX A;  4BXX D;  3PIW A;  5EQI A;  3H3V E;  4J4L C;  2O26 A;  1CN4 C;  3DGC L;  5KNH I;  3N06 A;  4YQX A;  1EKU A;  1A9C A;  1GNC A;  3PO2 D;  1Z92 A;  3HOY D;  4ZYR A;  3HOW D;  1LK3 A;  3I4M D;  4A3D D;  2H24 A;  4GC0 A;  3Q1S I;  3UX9 A;  5IP9 D;  1GA3 A;  1V7M V;  4NN7 A;  3OG4 A;  1Y1V D;  1FBX A;  3LB6 A;  5EQH A;  2KZ1 A;  3VA2 A;  2JA7 D;  4NE6 B;  1ALU A;  4A3C D;  3LW5 G;  5A2N A;  1PV6 A;  1AU1 A;  5IP7 D;  1LKI A;  2B8X A;  2Z3R A;  3SE4 B;  1M4R A;  2P11 A;  1F6F A;  1M4A A;  4GS7 A;  2JA6 D;  2B5I A;  2INT A;  4U4V A;  1EVS A;  4DKF A;  2WSC K;  3DLQ I;  2B8Y A;  4QPM A;  3O7P A;  2ERJ D;  2L3Y A;  4NE3 B;  3EW3 A;  4D2B A;  3DI2 A;  5EQG A;  1IAR A;  4DOH A;  4ZW9 A;  1CYL A;  1BCN A;  1N3S A;  1AIP C;  5FHX A;  1FG9 A;  4JA3 A;  3NCB A;  1WPL A;  2B8Z A;  5C44 D;  3HOV D;  2Q14 A;  3IRH A;  2R7Z D;  1EXZ A;  3PIV A;  4X51 A; 
#chains in the Genus database with same CATH homology
 1IS7 A;  4IU8 A;  1N3R A;  4IKX A;  4E44 B;  4IKZ A;  5EQI A;  4DU6 A;  5D59 A;  4ZWC A;  1FB1 A;  1A9C A;  4D2D A;  4ZYR A;  4R8Q A;  1IS8 A;  4QIQ A;  4NE5 B;  4GC0 A;  5D58 A;  4OH3 A;  2V8N A;  1GTP A;  4XNJ A;  1FBX A;  1WM9 A;  4DRB J;  5EQH A;  4XNI A;  1WUQ A;  4NE6 B;  4APS A;  5A2N A;  1PV6 A;  3WDO A;  1WUR A;  5D6K A;  4U4T A;  4Q65 A;  1PV7 A;  4IKY A;  1N3T A;  4YB9 D;  4UVM A;  4IKV A;  1EFU B;  4D2C A;  4DRA E;  2KR1 A;  3VEJ A;  2Y5Y A;  2PN0 A;  1PW4 A;  1TFE A;  2P11 A;  4ZWB A;  5C65 A;  4GBZ A;  2XUT A;  5A2O A;  4Q7J A;  4YBQ A;  4U4V A;  4JRE A;  4W6V A;  3O7Q A;  4PYP A;  4JR9 A;  4U4W A;  3B0B C;  4IKW A;  4QPM A;  3O7P A;  4NE3 B;  4OAA A;  4D2B A;  5EQG A;  4J05 A;  5GXB A;  4GBY A;  3BMB A;  4ZW9 A;  2CFP A;  4TPG A;  1N3S A;  1AIP C;  4LEP A;  4TPH A;  2LNZ A;  2CFQ A;  1EL6 A;  1A8R A;  4JA3 A;  1WPL A;  2LO0 A;  4IU9 A;  4TPJ A;  5DMZ A;  4E45 B;  4LDS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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