4JA3A

Partially occluded inward open conformation of the xylose transporter xyle from e. coli
Total Genus 174
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
174
sequence length
458
structure length
426
Chain Sequence
SYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVAPQNLSESAANSLLGFCVASALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGSAWPELGFTSINPDNTVPVYLAGYVPEFVIYRIIGGIGVGLASMLSPMYIAELAPAHIRGKLVSFNQFAIIFGQLLVYCVNYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLYTVPESPRWLMSRGKQEQAEGILRKIMGNTLATQAVQEIKHSLDHGRGVIVIGVMLSIFQQFVGINVVLYYAPEVSTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKPLQIIGALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSWGPVCWVLLSEALAIAVAAQWLANYFVSWTFPMMDKNSHNGFSYWIYGCMGVLAALFMWKFVPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords D-xylose-proton symporter
total genus 174
structure length 426
sequence length 458
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-02-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00083 Sugar_tr Sugar (and other) transporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.90 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ja3A02
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4ja3A01
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4ja3A03
4XNJA 4IKWA 5C65A 1PV7A 4IU8A 4Q65A 4LDSA 4ZWBA 5EQIA 3O7PA 4U4WA 5A2OA 4UVMA 4D2DA 4W6VA 4GBYA 4TPHA 4TPJA 4ZWCA 4D2CA 5D58A 1PV6A 4IKYA 5D59A 5D6KA 1PW4A 4IKXA 2XUTA 3O7QA 4QIQA 4APSA 4YBQA 5EQHA 4YB9D 4ZYRA 4J05A 4D2BA 5A2NA 4JREA 4U4VA 4ZW9A 5EQGA 4JA3A 4JR9A 4PYPA 2CFPA 5GXBA 4GBZA 4OAAA 4OH3A 4U4TA 3WDOA 4GC0A 4IKZA 4IKVA 2CFQA 2Y5YA 4LEPA 4IU9A 4TPGA 4XNIA 2V8NA
chains in the Genus database with same CATH superfamily
1D9CA 3BPLA 5D22A 4GBYA 3DGCL 1J7VL 5D59A 4FA8E 2INTA 1FBXA 3S9DA 2H24A 5IYCD 1HIJA 1EMRA 1RW5A 2B8ZA 4XNIA 1QVNA 3QB7A 4Q7JA 1SCFA 1EERA 3AYHA 3L5WI 2B8YA 3L5XA 5FHXA 1M4AA 1ETEA 1ALUA 1V7MV 1D9GA 2O27A 2C35A 5D72A 3HOUD 3HOYD 3PO3D 3HOWD 4ZS7A 1BP3A 1CN4C 3IRHA 5D71A 5EQIA 4UVMA 1KF9A 1A9CA 2Q98A 1Y14A 4A3BD 4CNIC 3PIWA 4APSA 4J05A 2B5IA 1Z7CA 3DI2A 3B0BC 1B5LA 3OG4A 3NCBA 3WDOA 4LRLA 2B8XA 2WSCG 4OH3A 1LQSL 5C65A 1F6FA 2Z3QA 1I1RB 2KR1A 1NBPA 5C3ED 1LK3A 1A7MA 4DKFA 3QWRB 2WSEK 5FUCA 1PW4A 3VEJA 5EQGA 4GRWA 4GBZA 4PS4A 3BPOA 4U4TA 4X51A 4A3MD 4A93D 2WSFK 4DRBJ 3TGXB 4ZF7A 3OG6A 1Z92A 3WCYI 5IYBD 2E9WC 4DU6A 4Q65A 1WU3I 1ITLA 2B90A 2R93D 1P9MB 4IKXA 4YUEC 4RS1A 4J4LC 4PYPA 2Z3RA 3DUHC 4OAAA 4E44B 1N3RA 5TS9A 2D9QA 4LEPA 4YPGC 1BGCA 1ITFA 1AXIA 3EJJA 1F45B 3O7PA 3D85C 4A3GD 4WRLB 5D6KA 4NE5B 1M47A 5EQHA 3VA2A 5GXBA 4IKZA 2JA7D 3SE3B 1N3SA 3NCCA 1IJZA 1IK0A 1BGEA 5C44D 2O6IA 1WCMD 1FG9A 3H0GD 2L3YA 1ITIA 4O6KA 5D58A 4NE3B 4NEJA 3LW5G 5E4EA 4ZW9A 1JLIA 1HUWA 1WPLA 2XQBA 3NCFA 1RFBA 1HZIA 1Y1WD 4NN5A 1BCNA 4BBRD 2VUMD 4DKDA 4R8QA 4ZWBA 3H3VE 2GMFA 3BPNA 3FKID 1A8RA 1EL6A 1BGDA 1FYHA 4A3ED 4A3KD 1CNT1 1Y6ML 1LKIA 3QAZA 1HIKA 3G9VB 4LDSA 1TFEA 1BUYA 1M4RA 1YKBA 2D48A 1M4CA 2LNZA 5A2OA 4A3JD 3DI3A 1PGRA 4ZWCA 3SE4B 4EXNA 5IP9D 2OQPA 4YBQA 4U4VA 1PW6A 3G6DA 2CFPA 3D87A 1VLKA 4IKVA 3UF2A 1M49A 4DRAE 1EXZA 4O9HA 2JA6D 3UX9A 3UF5A 2JA5D 2L3OA 3HHRA 3BESL 4W6VA 2WSEG 4E45B 4D2CA 1PV6A 4NI7A 3Q1SI 1WURA 5C7XA 1EVSA 2XUTA 1HGUA 4QIQA 3PO2D 4ZYRA 1IS7A 4A3DD 2R7ZD 1IARA 2Q7NB 4YQXA 5D28B 4A3LD 2PSMA 1PV7A 1Y6KL 1BBNA 3N06A 4NEMA 4IKYA 3D48P 1IS8A 2LMSA 4MHLA 4DKCA 1RCBA 1WM9A 1PVHB 1N3TA 3INKC 4EXPA 1GTPA 1AIPC 1WUQA 1V7NV 4GS7A 1CSGA 4TPGA 5IYDD 1A22A 4BY7D 2LO0A 4QPMA 2B8UA 3DLQI 4NI9A 4A3ID 3QT2C 3LB6B 3LW5K 1M48A 2LAGA 4NKQC 4JR9A 2O01G 1HWHA 3NPZA 2CFQA 2HYMB 5KNHI 4YDYI 1M4BA 4XNJA 4Z5RD 2Q14A 1CD9A 1CYLA 1HULA 4U4WA 1AU1A 4D2DA 4TPJA 1EKUA 2B63D 3N0PA 4NN6A 3BMBA 5A2NA 2KZ1A 3MZGA 4DOHA 1IL6A 2JA8D 4BBSD 2WSCK 4BXXD 1INRA 3B5KA 2ERJD 1N1FA 3UEZE 3I4ND 4D2BA 3HMXB 3LB6A 4A3CD 3NCEA 4NN7A 1FB1A 3HOXD 4IU9A 2V8NA 5FLMD 4IU8A 1HWGA 3OQ3A 3HHCA 4NE6B 4TPHA 1IRLA 2B91A 1Y6NL 3PIVA 1PY2A 5IP7D 3O7QA 1ITMA 2P11A 4BY1D 3EW3A 4JREA 3HOVD 2CYKA 4GC0A 2WSFG 1GNCA 3HOZD 2O26A 4IKWA 5LQBA 2IL6A 5L6YC 1RHGA 4I77Z 3I4MD 1AX8A 2R92D 1EFUB 1GA3A 3QB1A 2PN0A 5D70A 2ILKA 4YB9D 4A3FD 5C4XD 1Y1VD 4JA3A 4DKEA 5DMZA 2Y5YA 1ILKA
chains in the Genus database with same CATH topology
4XNJA 4Q65A 4DU6A 2LNZA 4U4WA 5A2OA 4D2DA 4GBYA 4TPJA 4ZWCA 5D59A 4IKXA 4YBQA 3BMBA 1FBXA 5A2NA 4U4VA 4PYPA 2CFPA 4OAAA 4E44B 4IKVA 1N3RA 4DRAE 4LEPA 4XNIA 4Q7JA 3O7PA 4W6VA 4E45B 4D2CA 1PV6A 1WURA 5D6KA 4NE5B 2XUTA 4QIQA 5EQHA 4ZYRA 1IS7A 4D2BA 5GXBA 4IKZA 1FB1A 1N3SA 4IU9A 2V8NA 1PV7A 4IU8A 1TFEA 5EQIA 4UVMA 4NE6B 4TPHA 1A9CA 5D58A 4IKYA 4NE3B 1IS8A 3O7QA 4APSA 2P11A 4J05A 4JREA 4ZW9A 1WM9A 1WPLA 3B0BC 1N3TA 1GTPA 3WDOA 1AIPC 4GC0A 1WUQA 4OH3A 4TPGA 4IKWA 5C65A 2KR1A 4R8QA 4ZWBA 1EFUB 2LO0A 4QPMA 2PN0A 1PW4A 1A8RA 3VEJA 4YB9D 1EL6A 5EQGA 4JA3A 4JR9A 4GBZA 4U4TA 5DMZA 4DRBJ 2CFQA 2Y5YA 4LDSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XNJ A;  4IKW A;  5C65 A;  1PV7 A;  4IU8 A;  4Q65 A;  4LDS A;  4ZWB A;  5EQI A;  3O7P A;  4U4W A;  5A2O A;  4UVM A;  4D2D A;  4W6V A;  4GBY A;  4TPH A;  4TPJ A;  4ZWC A;  4D2C A;  5D58 A;  1PV6 A;  4IKY A;  5D59 A;  5D6K A;  1PW4 A;  4IKX A;  2XUT A;  3O7Q A;  4QIQ A;  4APS A;  4YBQ A;  5EQH A;  4YB9 D;  4ZYR A;  4J05 A;  4D2B A;  5A2N A;  4JRE A;  4U4V A;  4ZW9 A;  5EQG A;  4JA3 A;  4JR9 A;  4PYP A;  2CFP A;  5GXB A;  4GBZ A;  4OAA A;  4OH3 A;  4U4T A;  3WDO A;  4GC0 A;  4IKZ A;  4IKV A;  2CFQ A;  2Y5Y A;  4LEP A;  4IU9 A;  4TPG A;  4XNI A;  2V8N A; 
#chains in the Genus database with same CATH topology
 1D9C A;  3BPL A;  5D22 A;  4GBY A;  3DGC L;  1J7V L;  5D59 A;  4FA8 E;  2INT A;  1FBX A;  3S9D A;  2H24 A;  5IYC D;  1HIJ A;  1EMR A;  1RW5 A;  2B8Z A;  4XNI A;  1QVN A;  3QB7 A;  4Q7J A;  1SCF A;  1EER A;  3AYH A;  3L5W I;  2B8Y A;  3L5X A;  5FHX A;  1M4A A;  1ETE A;  1ALU A;  1V7M V;  1D9G A;  2O27 A;  2C35 A;  5D72 A;  3HOU D;  3HOY D;  3PO3 D;  3HOW D;  4ZS7 A;  1BP3 A;  1CN4 C;  3IRH A;  5D71 A;  5EQI A;  4UVM A;  1KF9 A;  1A9C A;  2Q98 A;  1Y14 A;  4A3B D;  4CNI C;  3PIW A;  4APS A;  4J05 A;  2B5I A;  1Z7C A;  3DI2 A;  3B0B C;  1B5L A;  3OG4 A;  3NCB A;  3WDO A;  4LRL A;  2B8X A;  2WSC G;  4OH3 A;  1LQS L;  5C65 A;  1F6F A;  2Z3Q A;  1I1R B;  2KR1 A;  1NBP A;  5C3E D;  1LK3 A;  1A7M A;  4DKF A;  3QWR B;  2WSE K;  5FUC A;  1PW4 A;  3VEJ A;  5EQG A;  4GRW A;  4GBZ A;  4PS4 A;  3BPO A;  4U4T A;  4X51 A;  4A3M D;  4A93 D;  2WSF K;  4DRB J;  3TGX B;  4ZF7 A;  3OG6 A;  1Z92 A;  3WCY I;  5IYB D;  2E9W C;  4DU6 A;  4Q65 A;  1WU3 I;  1ITL A;  2B90 A;  2R93 D;  1P9M B;  4IKX A;  4YUE C;  4RS1 A;  4J4L C;  4PYP A;  2Z3R A;  3DUH C;  4OAA A;  4E44 B;  1N3R A;  5TS9 A;  2D9Q A;  4LEP A;  4YPG C;  1BGC A;  1ITF A;  1AXI A;  3EJJ A;  1F45 B;  3O7P A;  3D85 C;  4A3G D;  4WRL B;  5D6K A;  4NE5 B;  1M47 A;  5EQH A;  3VA2 A;  5GXB A;  4IKZ A;  2JA7 D;  3SE3 B;  1N3S A;  3NCC A;  1IJZ A;  1IK0 A;  1BGE A;  5C44 D;  2O6I A;  1WCM D;  1FG9 A;  3H0G D;  2L3Y A;  1ITI A;  4O6K A;  5D58 A;  4NE3 B;  4NEJ A;  3LW5 G;  5E4E A;  4ZW9 A;  1JLI A;  1HUW A;  1WPL A;  2XQB A;  3NCF A;  1RFB A;  1HZI A;  1Y1W D;  4NN5 A;  1BCN A;  4BBR D;  2VUM D;  4DKD A;  4R8Q A;  4ZWB A;  3H3V E;  2GMF A;  3BPN A;  3FKI D;  1A8R A;  1EL6 A;  1BGD A;  1FYH A;  4A3E D;  4A3K D;  1CNT 1;  1Y6M L;  1LKI A;  3QAZ A;  1HIK A;  3G9V B;  4LDS A;  1TFE A;  1BUY A;  1M4R A;  1YKB A;  2D48 A;  1M4C A;  2LNZ A;  5A2O A;  4A3J D;  3DI3 A;  1PGR A;  4ZWC A;  3SE4 B;  4EXN A;  5IP9 D;  2OQP A;  4YBQ A;  4U4V A;  1PW6 A;  3G6D A;  2CFP A;  3D87 A;  1VLK A;  4IKV A;  3UF2 A;  1M49 A;  4DRA E;  1EXZ A;  4O9H A;  2JA6 D;  3UX9 A;  3UF5 A;  2JA5 D;  2L3O A;  3HHR A;  3BES L;  4W6V A;  2WSE G;  4E45 B;  4D2C A;  1PV6 A;  4NI7 A;  3Q1S I;  1WUR A;  5C7X A;  1EVS A;  2XUT A;  1HGU A;  4QIQ A;  3PO2 D;  4ZYR A;  1IS7 A;  4A3D D;  2R7Z D;  1IAR A;  2Q7N B;  4YQX A;  5D28 B;  4A3L D;  2PSM A;  1PV7 A;  1Y6K L;  1BBN A;  3N06 A;  4NEM A;  4IKY A;  3D48 P;  1IS8 A;  2LMS A;  4MHL A;  4DKC A;  1RCB A;  1WM9 A;  1PVH B;  1N3T A;  3INK C;  4EXP A;  1GTP A;  1AIP C;  1WUQ A;  1V7N V;  4GS7 A;  1CSG A;  4TPG A;  5IYD D;  1A22 A;  4BY7 D;  2LO0 A;  4QPM A;  2B8U A;  3DLQ I;  4NI9 A;  4A3I D;  3QT2 C;  3LB6 B;  3LW5 K;  1M48 A;  2LAG A;  4NKQ C;  4JR9 A;  2O01 G;  1HWH A;  3NPZ A;  2CFQ A;  2HYM B;  5KNH I;  4YDY I;  1M4B A;  4XNJ A;  4Z5R D;  2Q14 A;  1CD9 A;  1CYL A;  1HUL A;  4U4W A;  1AU1 A;  4D2D A;  4TPJ A;  1EKU A;  2B63 D;  3N0P A;  4NN6 A;  3BMB A;  5A2N A;  2KZ1 A;  3MZG A;  4DOH A;  1IL6 A;  2JA8 D;  4BBS D;  2WSC K;  4BXX D;  1INR A;  3B5K A;  2ERJ D;  1N1F A;  3UEZ E;  3I4N D;  4D2B A;  3HMX B;  3LB6 A;  4A3C D;  3NCE A;  4NN7 A;  1FB1 A;  3HOX D;  4IU9 A;  2V8N A;  5FLM D;  4IU8 A;  1HWG A;  3OQ3 A;  3HHC A;  4NE6 B;  4TPH A;  1IRL A;  2B91 A;  1Y6N L;  3PIV A;  1PY2 A;  5IP7 D;  3O7Q A;  1ITM A;  2P11 A;  4BY1 D;  3EW3 A;  4JRE A;  3HOV D;  2CYK A;  4GC0 A;  2WSF G;  1GNC A;  3HOZ D;  2O26 A;  4IKW A;  5LQB A;  2IL6 A;  5L6Y C;  1RHG A;  4I77 Z;  3I4M D;  1AX8 A;  2R92 D;  1EFU B;  1GA3 A;  3QB1 A;  2PN0 A;  5D70 A;  2ILK A;  4YB9 D;  4A3F D;  5C4X D;  1Y1V D;  4JA3 A;  4DKE A;  5DMZ A;  2Y5Y A;  1ILK A; 
#chains in the Genus database with same CATH homology
 4XNJ A;  4Q65 A;  4DU6 A;  2LNZ A;  4U4W A;  5A2O A;  4D2D A;  4GBY A;  4TPJ A;  4ZWC A;  5D59 A;  4IKX A;  4YBQ A;  3BMB A;  1FBX A;  5A2N A;  4U4V A;  4PYP A;  2CFP A;  4OAA A;  4E44 B;  4IKV A;  1N3R A;  4DRA E;  4LEP A;  4XNI A;  4Q7J A;  3O7P A;  4W6V A;  4E45 B;  4D2C A;  1PV6 A;  1WUR A;  5D6K A;  4NE5 B;  2XUT A;  4QIQ A;  5EQH A;  4ZYR A;  1IS7 A;  4D2B A;  5GXB A;  4IKZ A;  1FB1 A;  1N3S A;  4IU9 A;  2V8N A;  1PV7 A;  4IU8 A;  1TFE A;  5EQI A;  4UVM A;  4NE6 B;  4TPH A;  1A9C A;  5D58 A;  4IKY A;  4NE3 B;  1IS8 A;  3O7Q A;  4APS A;  2P11 A;  4J05 A;  4JRE A;  4ZW9 A;  1WM9 A;  1WPL A;  3B0B C;  1N3T A;  1GTP A;  3WDO A;  1AIP C;  4GC0 A;  1WUQ A;  4OH3 A;  4TPG A;  4IKW A;  5C65 A;  2KR1 A;  4R8Q A;  4ZWB A;  1EFU B;  2LO0 A;  4QPM A;  2PN0 A;  1PW4 A;  1A8R A;  3VEJ A;  4YB9 D;  1EL6 A;  5EQG A;  4JA3 A;  4JR9 A;  4GBZ A;  4U4T A;  5DMZ A;  4DRB J;  2CFQ A;  2Y5Y A;  4LDS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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