4JA3A

Partially occluded inward open conformation of the xylose transporter xyle from e. coli
Total Genus 174
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
174
sequence length
458
structure length
426
Chain Sequence
SYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVAPQNLSESAANSLLGFCVASALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGSAWPELGFTSINPDNTVPVYLAGYVPEFVIYRIIGGIGVGLASMLSPMYIAELAPAHIRGKLVSFNQFAIIFGQLLVYCVNYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLYTVPESPRWLMSRGKQEQAEGILRKIMGNTLATQAVQEIKHSLDHGRGVIVIGVMLSIFQQFVGINVVLYYAPEVSTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKPLQIIGALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSWGPVCWVLLSEALAIAVAAQWLANYFVSWTFPMMDKNSHNGFSYWIYGCMGVLAALFMWKFVPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
source organism Escherichia coli
publication title Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters.
pubmed doi rcsb
molecule keywords D-xylose-proton symporter
total genus 174
structure length 426
sequence length 458
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-02-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00083 Sugar_tr Sugar (and other) transporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.90 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ja3A02
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4ja3A01
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4ja3A03
4IKYA 4UVMA 4ZWBA 4XNIA 4APSA 4ZWCA 2CFPA 4GC0A 4JR9A 4OH3A 1PW4A 4XNJA 5GXBA 5EQIA 2XUTA 4Q65A 5EQHA 4LEPA 4PYPA 2CFQA 4U4VA 4OAAA 4D2CA 4IU8A 4D2DA 4IU9A 4JREA 3WDOA 4U4WA 2V8NA 1PV6A 4IKWA 4IKZA 4TPHA 4ZYRA 4U4TA 3O7QA 5A2NA 4W6VA 5EQGA 4TPJA 4LDSA 4GBYA 5C65A 4IKXA 4J05A 4ZW9A 4IKVA 4D2BA 4TPGA 4JA3A 4QIQA 4YBQA 5D58A 2Y5YA 1PV7A 5A2OA 4YB9D 4GBZA 5D6KA 3O7PA 5D59A
chains in the Genus database with same CATH superfamily
2B5IA 1LK3A 3DLQI 2CFPA 4RS1A 5EQIA 1Y14A 3D48P 4TPHA 1HWGA 3NCEA 3Q1SI 1QVNA 1FG9A 3HOYD 2CFQA 3O7PA 4NEJA 1P9MB 4DRAE 4GRWA 5EQHA 3N06A 3VA2A 3BESL 1JLIA 1WCMD 4YPGC 1ETEA 1PW6A 1N3TA 5D22A 4NN6A 2B8UA 1Y6KL 3EJJA 4NEMA 4A3GD 1CN4C 5LQBA 3NCCA 1IJZA 1M4RA 5D72A 1M49A 4D2CA 4OAAA 2C35A 3NCFA 3D85C 4DKCA 2O6IA 1EVSA 2B8ZA 2B8YA 5C3ED 5IYBD 4D2BA 1INRA 3L5XA 2Q7NB 3OQ3A 5C44D 3PO3D 4E44B 3HHCA 4Q65A 1BP3A 3QAZA 1N1FA 3B0BC 4IU8A 1WPLA 3O7QA 5IP7D 3HOXD 1NBPA 3QB7A 2LNZA 3HOVD 5C65A 4IKXA 2IL6A 1A9CA 4BBSD 4GBZA 1Z92A 2WSEK 1RFBA 5D70A 1AXIA 1LKIA 4A3KD 4E45B 1HZIA 2VUMD 2D48A 4D2DA 1ITIA 1N3RA 4NN7A 3DI2A 2JA8D 2R92D 1HIKA 1YKBA 3L5WI 1AX8A 4FA8E 4A3CD 3PO2D 2PN0A 1FBXA 1ITFA 1Y1VD 3IRHA 1RCBA 3LB6B 1V7NV 2D9QA 5EQGA 4X51A 1HWHA 4I77Z 4LRLA 1V7MV 3S9DA 4A3JD 1A8RA 4DKEA 2HYMB 4YUEC 1CSGA 5D28B 4A3MD 4JR9A 1AIPC 1PW4A 3LW5G 1HIJA 1GA3A 2B91A 1BCNA 4ZYRA 2B63D 2R93D 3H0GD 2O01G 3LW5K 1PY2A 4NN5A 5KNHI 4YQXA 2Z3QA 4YBQA 4O6KA 1PGRA 3HOWD 4EXPA 3B5KA 1M4AA 4A3DD 4QPMA 4PYPA 4U4WA 5FLMD 4IKZA 4U4TA 4ZF7A 3HOZD 1EERA 2E9WC 4IKVA 4MHLA 2WSCG 4Z5RD 2B8XA 4UVMA 1HUWA 4IKYA 3SE4B 1IL6A 1BBNA 2WSCK 3NCBA 2JA5D 3D87A 4IU9A 2WSFG 1AU1A 1M48A 1J7VL 4W6VA 1VLKA 4A3FD 1FYHA 4JA3A 5D71A 3LB6A 1GTPA 3UF2A 2INTA 3EW3A 2JA6D 4XNJA 3N0PA 4A3LD 1WU3I 4O9HA 1Y6ML 1M4CA 1F6FA 2Z3RA 3G6DA 1I1RB 4IKWA 1GNCA 3PIVA 4DRBJ 1WURA 5IP9D 2KR1A 4A3ED 4J4LC 1BGEA 5E4EA 1BGCA 3UEZE 4YDYI 4QIQA 3HOUD 3BPOA 5A2OA 5D59A 3H3VE 3UF5A 4GC0A 4NE5B 1IRLA 2OQPA 4BBRD 4LEPA 1BUYA 4U4VA 1EFUB 3G9VB 1EXZA 3WDOA 4DKDA 1A22A 3QWRB 2CYKA 4GBYA 1M47A 2R7ZD 1B5LA 4NKQC 3PIWA 4DOHA 3HHRA 4ZWBA 1ILKA 3NPZA 4NE6B 3WCYI 1SCFA 3DUHC 2L3YA 4DKFA 4CNIC 5DMZA 4WRLB 5A2NA 1KF9A 2O26A 2ILKA 3INKC 2H24A 3MZGA 2LAGA 1D9GA 3BMBA 1N3SA 1FB1A 2Q14A 4PS4A 3BPLA 1PVHB 4DU6A 2ERJD 4XNIA 4ZWCA 3UX9A 1EKUA 1Z7CA 1CNT1 4BY1D 5C4XD 1EMRA 3TGXB 4Q7JA 1WUQA 2Y5YA 1BGDA 3HMXB 1WM9A 1HGUA 1RHGA 1TFEA 3QT2C 4OH3A 1IARA 5GXBA 2XUTA 2KZ1A 3DGCL 2Q98A 3QB1A 5C7XA 3BPNA 1RW5A 1LQSL 2PSMA 1ITMA 4ZW9A 2O27A 2WSFK 1IS8A 4NI7A 4BXXD 5IYCD 4NI9A 5D6KA 4A3ID 5FHXA 5TS9A 3I4ND 1CYLA 3DI3A 2GMFA 2JA7D 3OG4A 2XQBA 4JREA 1PV6A 5FUCA 3VEJA 2B90A 4NE3B 1CD9A 1F45B 1Y6NL 3AYHA 2WSEG 4J05A 2L3OA 4GS7A 1M4BA 1D9CA 1PV7A 2LMSA 4A3BD 4TPGA 1ALUA 4APSA 4R8QA 1HULA 1EL6A 4BY7D 1IK0A 1ITLA 3SE3B 5IYDD 2P11A 4A93D 3OG6A 2V8NA 4ZS7A 4TPJA 4LDSA 1IS7A 4EXNA 3I4MD 5L6YC 1A7MA 1Y1WD 5D58A 4YB9D 2LO0A 3FKID
chains in the Genus database with same CATH topology
4DU6A 4IKYA 4XNIA 4ZWCA 2CFPA 5EQIA 4E45B 4D2DA 4IU9A 1N3RA 4TPHA 4W6VA 4Q7JA 1WUQA 4JA3A 2Y5YA 3O7PA 2CFQA 1GTPA 1WM9A 1TFEA 4DRAE 2PN0A 4OH3A 4XNJA 1FBXA 5GXBA 5EQHA 2XUTA 4IKWA 5EQGA 1N3TA 4DRBJ 1WURA 2LO0A 2KR1A 4ZW9A 1A8RA 1IS8A 4QIQA 5A2OA 5D6KA 5D59A 4GC0A 4NE5B 4JR9A 1AIPC 1PW4A 4LEPA 4U4VA 4D2CA 4OAAA 1EFUB 4JREA 3WDOA 1PV6A 4ZYRA 3VEJA 4NE3B 4GBYA 4J05A 4D2BA 4YBQA 1PV7A 4TPGA 4ZWBA 4APSA 4R8QA 4E44B 1EL6A 4NE6B 4Q65A 2P11A 4QPMA 4PYPA 3B0BC 4IU8A 1WPLA 4U4WA 5DMZA 2V8NA 4IKZA 5A2NA 4U4TA 3O7QA 4TPJA 4LDSA 1IS7A 2LNZA 5C65A 4IKXA 4IKVA 3BMBA 1A9CA 5D58A 1N3SA 4YB9D 1FB1A 4GBZA 4UVMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IKY A;  4UVM A;  4ZWB A;  4XNI A;  4APS A;  4ZWC A;  2CFP A;  4GC0 A;  4JR9 A;  4OH3 A;  1PW4 A;  4XNJ A;  5GXB A;  5EQI A;  2XUT A;  4Q65 A;  5EQH A;  4LEP A;  4PYP A;  2CFQ A;  4U4V A;  4OAA A;  4D2C A;  4IU8 A;  4D2D A;  4IU9 A;  4JRE A;  3WDO A;  4U4W A;  2V8N A;  1PV6 A;  4IKW A;  4IKZ A;  4TPH A;  4ZYR A;  4U4T A;  3O7Q A;  5A2N A;  4W6V A;  5EQG A;  4TPJ A;  4LDS A;  4GBY A;  5C65 A;  4IKX A;  4J05 A;  4ZW9 A;  4IKV A;  4D2B A;  4TPG A;  4JA3 A;  4QIQ A;  4YBQ A;  5D58 A;  2Y5Y A;  1PV7 A;  5A2O A;  4YB9 D;  4GBZ A;  5D6K A;  3O7P A;  5D59 A; 
#chains in the Genus database with same CATH topology
 2B5I A;  1LK3 A;  3DLQ I;  2CFP A;  4RS1 A;  5EQI A;  1Y14 A;  3D48 P;  4TPH A;  1HWG A;  3NCE A;  3Q1S I;  1QVN A;  1FG9 A;  3HOY D;  2CFQ A;  3O7P A;  4NEJ A;  1P9M B;  4DRA E;  4GRW A;  5EQH A;  3N06 A;  3VA2 A;  3BES L;  1JLI A;  1WCM D;  4YPG C;  1ETE A;  1PW6 A;  1N3T A;  5D22 A;  4NN6 A;  2B8U A;  1Y6K L;  3EJJ A;  4NEM A;  4A3G D;  1CN4 C;  5LQB A;  3NCC A;  1IJZ A;  1M4R A;  5D72 A;  1M49 A;  4D2C A;  4OAA A;  2C35 A;  3NCF A;  3D85 C;  4DKC A;  2O6I A;  1EVS A;  2B8Z A;  2B8Y A;  5C3E D;  5IYB D;  4D2B A;  1INR A;  3L5X A;  2Q7N B;  3OQ3 A;  5C44 D;  3PO3 D;  4E44 B;  3HHC A;  4Q65 A;  1BP3 A;  3QAZ A;  1N1F A;  3B0B C;  4IU8 A;  1WPL A;  3O7Q A;  5IP7 D;  3HOX D;  1NBP A;  3QB7 A;  2LNZ A;  3HOV D;  5C65 A;  4IKX A;  2IL6 A;  1A9C A;  4BBS D;  4GBZ A;  1Z92 A;  2WSE K;  1RFB A;  5D70 A;  1AXI A;  1LKI A;  4A3K D;  4E45 B;  1HZI A;  2VUM D;  2D48 A;  4D2D A;  1ITI A;  1N3R A;  4NN7 A;  3DI2 A;  2JA8 D;  2R92 D;  1HIK A;  1YKB A;  3L5W I;  1AX8 A;  4FA8 E;  4A3C D;  3PO2 D;  2PN0 A;  1FBX A;  1ITF A;  1Y1V D;  3IRH A;  1RCB A;  3LB6 B;  1V7N V;  2D9Q A;  5EQG A;  4X51 A;  1HWH A;  4I77 Z;  4LRL A;  1V7M V;  3S9D A;  4A3J D;  1A8R A;  4DKE A;  2HYM B;  4YUE C;  1CSG A;  5D28 B;  4A3M D;  4JR9 A;  1AIP C;  1PW4 A;  3LW5 G;  1HIJ A;  1GA3 A;  2B91 A;  1BCN A;  4ZYR A;  2B63 D;  2R93 D;  3H0G D;  2O01 G;  3LW5 K;  1PY2 A;  4NN5 A;  5KNH I;  4YQX A;  2Z3Q A;  4YBQ A;  4O6K A;  1PGR A;  3HOW D;  4EXP A;  3B5K A;  1M4A A;  4A3D D;  4QPM A;  4PYP A;  4U4W A;  5FLM D;  4IKZ A;  4U4T A;  4ZF7 A;  3HOZ D;  1EER A;  2E9W C;  4IKV A;  4MHL A;  2WSC G;  4Z5R D;  2B8X A;  4UVM A;  1HUW A;  4IKY A;  3SE4 B;  1IL6 A;  1BBN A;  2WSC K;  3NCB A;  2JA5 D;  3D87 A;  4IU9 A;  2WSF G;  1AU1 A;  1M48 A;  1J7V L;  4W6V A;  1VLK A;  4A3F D;  1FYH A;  4JA3 A;  5D71 A;  3LB6 A;  1GTP A;  3UF2 A;  2INT A;  3EW3 A;  2JA6 D;  4XNJ A;  3N0P A;  4A3L D;  1WU3 I;  4O9H A;  1Y6M L;  1M4C A;  1F6F A;  2Z3R A;  3G6D A;  1I1R B;  4IKW A;  1GNC A;  3PIV A;  4DRB J;  1WUR A;  5IP9 D;  2KR1 A;  4A3E D;  4J4L C;  1BGE A;  5E4E A;  1BGC A;  3UEZ E;  4YDY I;  4QIQ A;  3HOU D;  3BPO A;  5A2O A;  5D59 A;  3H3V E;  3UF5 A;  4GC0 A;  4NE5 B;  1IRL A;  2OQP A;  4BBR D;  4LEP A;  1BUY A;  4U4V A;  1EFU B;  3G9V B;  1EXZ A;  3WDO A;  4DKD A;  1A22 A;  3QWR B;  2CYK A;  4GBY A;  1M47 A;  2R7Z D;  1B5L A;  4NKQ C;  3PIW A;  4DOH A;  3HHR A;  4ZWB A;  1ILK A;  3NPZ A;  4NE6 B;  3WCY I;  1SCF A;  3DUH C;  2L3Y A;  4DKF A;  4CNI C;  5DMZ A;  4WRL B;  5A2N A;  1KF9 A;  2O26 A;  2ILK A;  3INK C;  2H24 A;  3MZG A;  2LAG A;  1D9G A;  3BMB A;  1N3S A;  1FB1 A;  2Q14 A;  4PS4 A;  3BPL A;  1PVH B;  4DU6 A;  2ERJ D;  4XNI A;  4ZWC A;  3UX9 A;  1EKU A;  1Z7C A;  1CNT 1;  4BY1 D;  5C4X D;  1EMR A;  3TGX B;  4Q7J A;  1WUQ A;  2Y5Y A;  1BGD A;  3HMX B;  1WM9 A;  1HGU A;  1RHG A;  1TFE A;  3QT2 C;  4OH3 A;  1IAR A;  5GXB A;  2XUT A;  2KZ1 A;  3DGC L;  2Q98 A;  3QB1 A;  5C7X A;  3BPN A;  1RW5 A;  1LQS L;  2PSM A;  1ITM A;  4ZW9 A;  2O27 A;  2WSF K;  1IS8 A;  4NI7 A;  4BXX D;  5IYC D;  4NI9 A;  5D6K A;  4A3I D;  5FHX A;  5TS9 A;  3I4N D;  1CYL A;  3DI3 A;  2GMF A;  2JA7 D;  3OG4 A;  2XQB A;  4JRE A;  1PV6 A;  5FUC A;  3VEJ A;  2B90 A;  4NE3 B;  1CD9 A;  1F45 B;  1Y6N L;  3AYH A;  2WSE G;  4J05 A;  2L3O A;  4GS7 A;  1M4B A;  1D9C A;  1PV7 A;  2LMS A;  4A3B D;  4TPG A;  1ALU A;  4APS A;  4R8Q A;  1HUL A;  1EL6 A;  4BY7 D;  1IK0 A;  1ITL A;  3SE3 B;  5IYD D;  2P11 A;  4A93 D;  3OG6 A;  2V8N A;  4ZS7 A;  4TPJ A;  4LDS A;  1IS7 A;  4EXN A;  3I4M D;  5L6Y C;  1A7M A;  1Y1W D;  5D58 A;  4YB9 D;  2LO0 A;  3FKI D; 
#chains in the Genus database with same CATH homology
 4DU6 A;  4IKY A;  4XNI A;  4ZWC A;  2CFP A;  5EQI A;  4E45 B;  4D2D A;  4IU9 A;  1N3R A;  4TPH A;  4W6V A;  4Q7J A;  1WUQ A;  4JA3 A;  2Y5Y A;  3O7P A;  2CFQ A;  1GTP A;  1WM9 A;  1TFE A;  4DRA E;  2PN0 A;  4OH3 A;  4XNJ A;  1FBX A;  5GXB A;  5EQH A;  2XUT A;  4IKW A;  5EQG A;  1N3T A;  4DRB J;  1WUR A;  2LO0 A;  2KR1 A;  4ZW9 A;  1A8R A;  1IS8 A;  4QIQ A;  5A2O A;  5D6K A;  5D59 A;  4GC0 A;  4NE5 B;  4JR9 A;  1AIP C;  1PW4 A;  4LEP A;  4U4V A;  4D2C A;  4OAA A;  1EFU B;  4JRE A;  3WDO A;  1PV6 A;  4ZYR A;  3VEJ A;  4NE3 B;  4GBY A;  4J05 A;  4D2B A;  4YBQ A;  1PV7 A;  4TPG A;  4ZWB A;  4APS A;  4R8Q A;  4E44 B;  1EL6 A;  4NE6 B;  4Q65 A;  2P11 A;  4QPM A;  4PYP A;  3B0B C;  4IU8 A;  1WPL A;  4U4W A;  5DMZ A;  2V8N A;  4IKZ A;  5A2N A;  4U4T A;  3O7Q A;  4TPJ A;  4LDS A;  1IS7 A;  2LNZ A;  5C65 A;  4IKX A;  4IKV A;  3BMB A;  1A9C A;  5D58 A;  1N3S A;  4YB9 D;  1FB1 A;  4GBZ A;  4UVM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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