4JA3A

Partially occluded inward open conformation of the xylose transporter xyle from e. coli
Total Genus 174
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
174
sequence length
458
structure length
426
Chain Sequence
SYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVAPQNLSESAANSLLGFCVASALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGSAWPELGFTSINPDNTVPVYLAGYVPEFVIYRIIGGIGVGLASMLSPMYIAELAPAHIRGKLVSFNQFAIIFGQLLVYCVNYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLYTVPESPRWLMSRGKQEQAEGILRKIMGNTLATQAVQEIKHSLDHGRGVIVIGVMLSIFQQFVGINVVLYYAPEVSTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKPLQIIGALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSWGPVCWVLLSEALAIAVAAQWLANYFVSWTFPMMDKNSHNGFSYWIYGCMGVLAALFMWKFVPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords D-xylose-proton symporter
total genus 174
structure length 426
sequence length 458
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-02-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00083 Sugar_tr Sugar (and other) transporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.90 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ja3A02
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4ja3A01
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4ja3A03
4D2BA 2CFQA 5A2OA 2Y5YA 4Q65A 4U4TA 4U4VA 4XNIA 5EQIA 3WDOA 2V8NA 4GBYA 5A2NA 4UVMA 4JREA 4IKZA 1PW4A 1PV6A 3O7PA 4LEPA 4APSA 4U4WA 4TPJA 4OH3A 4QIQA 5EQHA 4ZWBA 4ZW9A 4D2DA 2XUTA 4JR9A 4OAAA 4W6VA 5D59A 4D2CA 4TPHA 5GXBA 4IU8A 4TPGA 5EQGA 4GBZA 4ZYRA 3O7QA 4YBQA 4IKWA 4GC0A 4YB9D 4LDSA 4XNJA 4IKVA 4IU9A 4IKYA 2CFPA 5D6KA 4PYPA 4JA3A 5C65A 4IKXA 4J05A 5D58A 1PV7A 4ZWCA
chains in the Genus database with same CATH superfamily
1IRLA 2B8XA 2V8NA 4JREA 1A8RA 1BGCA 4A3JD 3D87A 2XQBA 4BY1D 2B90A 5TS9A 2B5IA 1WU3I 4A3CD 1BCNA 4IU9A 2CFPA 1LQSL 3BPNA 3OQ3A 1EMRA 5IYDD 2R7ZD 2IL6A 5E4EA 1D9CA 4U4VA 5EQIA 1EERA 4NEJA 4IKZA 1M49A 4A3DD 1IJZA 1A22A 4D2DA 1ITMA 3UF2A 1EL6A 4NEMA 4GRWA 2JA6D 3I4MD 3N0PA 5C65A 2WSCG 4DU6A 4NI7A 3NCFA 1AX8A 1WM9A 1PW4A 1ALUA 3BPOA 5D71A 1BBNA 2O27A 3H0GD 1IARA 1HIJA 5C3ED 4XNJA 2B8YA 3L5XA 4BY7D 2L3OA 1Y1WD 1JLIA 4CNIC 2H24A 2OQPA 1GA3A 4NKQC 3N06A 3HMXB 4BBRD 4GBYA 1V7NV 1WCMD 5GXBA 4DKDA 3D85C 5C7XA 3G9VB 5IP7D 4R8QA 1AU1A 4GBZA 3UX9A 1ITLA 3L5WI 4WRLB 1FB1A 4NE5B 3DI3A 4LRLA 3HOZD 1WURA 2CFQA 2Y5YA 4NN6A 4BXXD 4A3BD 2ILKA 3LW5K 4TPJA 1CN4C 1WPLA 1PW6A 4EXNA 2E9WC 4TPGA 3HOYD 2D9QA 2Z3QA 1QVNA 4A3ID 3WDOA 1GNCA 2LO0A 4U4WA 1N1FA 1M4BA 5FLMD 4NI9A 4IU8A 5D28B 1N3SA 2R93D 2O01G 2Q7NB 3QT2C 4YBQA 4DRAE 3HHCA 4NE3B 4MHLA 4YDYI 4RS1A 4O6KA 1M4RA 5FUCA 4DKFA 1RCBA 3BPLA 2Q98A 3EJJA 2O26A 3I4ND 3B5KA 2L3YA 4IKWA 1Z7CA 4FA8E 2JA7D 1WUQA 1HULA 3UF5A 2PN0A 1Y1VD 4J05A 5D58A 4D2BA 1M4CA 5D22A 2Z3RA 4Q65A 1BGDA 3IRHA 4A3KD 3O7PA 1Y14A 1KF9A 1P9MB 2D48A 4O9HA 1F45B 3HOWD 3LB6B 3QB1A 2B8ZA 1CNT1 2GMFA 1YKBA 5DMZA 3HOVD 1V7MV 4ZS7A 1AIPC 4A3GD 5D70A 1INRA 4Z5RD 4OH3A 1BGEA 3S9DA 5C4XD 2LNZA 1GTPA 1AXIA 1ITIA 1IK0A 2WSFK 1CYLA 1A9CA 3AYHA 3DI2A 3NPZA 5LQBA 4BBSD 1CD9A 1D9GA 1IL6A 1PY2A 3VEJA 4NN5A 3FKID 1FBXA 4QIQA 5D72A 4JR9A 2C35A 1HUWA 1Z92A 1BP3A 2ERJD 1HWHA 3O7QA 1N3RA 5L6YC 2JA8D 4IKVA 2B63D 3SE4B 5KNHI 2R92D 4NE6B 3D48P 2O6IA 4J4LC 4DKCA 5FHXA 4ZF7A 3LB6A 1IS8A 3MZGA 2INTA 2VUMD 3Q1SI 5EQGA 4DOHA 2WSEK 2B91A 4YB9D 1LK3A 1VLKA 4IKYA 3OG4A 1A7MA 3WCYI 4JA3A 1NBPA 4IKXA 1I1RB 1PV7A 4ZWCA 2P11A 2KZ1A 2B8UA 3PO2D 4ZWBA 2XUTA 3QWRB 1F6FA 4GS7A 1HGUA 3VA2A 1PGRA 1Y6KL 2JA5D 5IYCD 3INKC 4PYPA 1Y6NL 3BMBA 1HIKA 2Q14A 1FYHA 4UVMA 4LEPA 3SE3B 4ZW9A 1TFEA 1SCFA 3G6DA 5IYBD 4A3LD 2WSFG 1ITFA 4E45B 3H3VE 3PIWA 1IS7A 4DKEA 3EW3A 1ETEA 3HOUD 3LW5G 1FG9A 3TGXB 4U4TA 4PS4A 1PV6A 4A3FD 4YPGC 1RHGA 4I77Z 3B0BC 4OAAA 1PVHB 4TPHA 4QPMA 3QB7A 3NCBA 4EXPA 1BUYA 1LKIA 1M4AA 3QAZA 1EFUB 1CSGA 5A2OA 4YQXA 4A93D 4XNIA 1RW5A 3DGCL 2LMSA 2WSEG 3DLQI 2WSCK 5C44D 4W6VA 5D59A 4D2CA 1M47A 3PO3D 1HZIA 4X51A 4A3MD 1N3TA 4Q7JA 3NCCA 1J7VL 2CYKA 3HOXD 3UEZE 4YUEC 1EKUA 1HWGA 3OG6A 4E44B 3HHRA 1EXZA 5A2NA 4A3ED 3PIVA 4APSA 5EQHA 2PSMA 1Y6ML 3BESL 4ZYRA 1ILKA 4NN7A 5IP9D 1RFBA 1EVSA 3NCEA 2KR1A 4LDSA 1M48A 3DUHC 5D6KA 1B5LA 2HYMB 4GC0A 2LAGA 4DRBJ
chains in the Genus database with same CATH topology
1WURA 2CFQA 2Y5YA 5DMZA 2V8NA 4UVMA 4JREA 1A8RA 4LEPA 1AIPC 4TPJA 4OH3A 1WPLA 4ZW9A 1TFEA 4TPGA 4E45B 2LNZA 1GTPA 1IS7A 4IU9A 2CFPA 1A9CA 4U4TA 4U4VA 5EQIA 3WDOA 3VEJA 4IKZA 2LO0A 1PV6A 4U4WA 1FBXA 4QIQA 4D2DA 3B0BC 4JR9A 4OAAA 4TPHA 4IU8A 1EL6A 4QPMA 1N3SA 3O7QA 1N3RA 4YBQA 4DRAE 4IKVA 4NE3B 5C65A 1EFUB 4DU6A 4NE6B 5A2OA 4XNIA 1WM9A 1PW4A 1IS8A 4W6VA 5D59A 4D2CA 5EQGA 1N3TA 4IKWA 4Q7JA 4YB9D 4XNJA 4IKYA 1WUQA 2PN0A 4JA3A 4IKXA 4J05A 5D58A 1PV7A 4ZWCA 4D2BA 4E44B 4Q65A 4GBYA 5A2NA 2P11A 5GXBA 3O7PA 4APSA 5EQHA 4ZWBA 2XUTA 4R8QA 4GBZA 4ZYRA 2KR1A 4LDSA 5D6KA 1FB1A 4NE5B 4PYPA 3BMBA 4GC0A 4DRBJ
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D2B A;  2CFQ A;  5A2O A;  2Y5Y A;  4Q65 A;  4U4T A;  4U4V A;  4XNI A;  5EQI A;  3WDO A;  2V8N A;  4GBY A;  5A2N A;  4UVM A;  4JRE A;  4IKZ A;  1PW4 A;  1PV6 A;  3O7P A;  4LEP A;  4APS A;  4U4W A;  4TPJ A;  4OH3 A;  4QIQ A;  5EQH A;  4ZWB A;  4ZW9 A;  4D2D A;  2XUT A;  4JR9 A;  4OAA A;  4W6V A;  5D59 A;  4D2C A;  4TPH A;  5GXB A;  4IU8 A;  4TPG A;  5EQG A;  4GBZ A;  4ZYR A;  3O7Q A;  4YBQ A;  4IKW A;  4GC0 A;  4YB9 D;  4LDS A;  4XNJ A;  4IKV A;  4IU9 A;  4IKY A;  2CFP A;  5D6K A;  4PYP A;  4JA3 A;  5C65 A;  4IKX A;  4J05 A;  5D58 A;  1PV7 A;  4ZWC A; 
#chains in the Genus database with same CATH topology
 1IRL A;  2B8X A;  2V8N A;  4JRE A;  1A8R A;  1BGC A;  4A3J D;  3D87 A;  2XQB A;  4BY1 D;  2B90 A;  5TS9 A;  2B5I A;  1WU3 I;  4A3C D;  1BCN A;  4IU9 A;  2CFP A;  1LQS L;  3BPN A;  3OQ3 A;  1EMR A;  5IYD D;  2R7Z D;  2IL6 A;  5E4E A;  1D9C A;  4U4V A;  5EQI A;  1EER A;  4NEJ A;  4IKZ A;  1M49 A;  4A3D D;  1IJZ A;  1A22 A;  4D2D A;  1ITM A;  3UF2 A;  1EL6 A;  4NEM A;  4GRW A;  2JA6 D;  3I4M D;  3N0P A;  5C65 A;  2WSC G;  4DU6 A;  4NI7 A;  3NCF A;  1AX8 A;  1WM9 A;  1PW4 A;  1ALU A;  3BPO A;  5D71 A;  1BBN A;  2O27 A;  3H0G D;  1IAR A;  1HIJ A;  5C3E D;  4XNJ A;  2B8Y A;  3L5X A;  4BY7 D;  2L3O A;  1Y1W D;  1JLI A;  4CNI C;  2H24 A;  2OQP A;  1GA3 A;  4NKQ C;  3N06 A;  3HMX B;  4BBR D;  4GBY A;  1V7N V;  1WCM D;  5GXB A;  4DKD A;  3D85 C;  5C7X A;  3G9V B;  5IP7 D;  4R8Q A;  1AU1 A;  4GBZ A;  3UX9 A;  1ITL A;  3L5W I;  4WRL B;  1FB1 A;  4NE5 B;  3DI3 A;  4LRL A;  3HOZ D;  1WUR A;  2CFQ A;  2Y5Y A;  4NN6 A;  4BXX D;  4A3B D;  2ILK A;  3LW5 K;  4TPJ A;  1CN4 C;  1WPL A;  1PW6 A;  4EXN A;  2E9W C;  4TPG A;  3HOY D;  2D9Q A;  2Z3Q A;  1QVN A;  4A3I D;  3WDO A;  1GNC A;  2LO0 A;  4U4W A;  1N1F A;  1M4B A;  5FLM D;  4NI9 A;  4IU8 A;  5D28 B;  1N3S A;  2R93 D;  2O01 G;  2Q7N B;  3QT2 C;  4YBQ A;  4DRA E;  3HHC A;  4NE3 B;  4MHL A;  4YDY I;  4RS1 A;  4O6K A;  1M4R A;  5FUC A;  4DKF A;  1RCB A;  3BPL A;  2Q98 A;  3EJJ A;  2O26 A;  3I4N D;  3B5K A;  2L3Y A;  4IKW A;  1Z7C A;  4FA8 E;  2JA7 D;  1WUQ A;  1HUL A;  3UF5 A;  2PN0 A;  1Y1V D;  4J05 A;  5D58 A;  4D2B A;  1M4C A;  5D22 A;  2Z3R A;  4Q65 A;  1BGD A;  3IRH A;  4A3K D;  3O7P A;  1Y14 A;  1KF9 A;  1P9M B;  2D48 A;  4O9H A;  1F45 B;  3HOW D;  3LB6 B;  3QB1 A;  2B8Z A;  1CNT 1;  2GMF A;  1YKB A;  5DMZ A;  3HOV D;  1V7M V;  4ZS7 A;  1AIP C;  4A3G D;  5D70 A;  1INR A;  4Z5R D;  4OH3 A;  1BGE A;  3S9D A;  5C4X D;  2LNZ A;  1GTP A;  1AXI A;  1ITI A;  1IK0 A;  2WSF K;  1CYL A;  1A9C A;  3AYH A;  3DI2 A;  3NPZ A;  5LQB A;  4BBS D;  1CD9 A;  1D9G A;  1IL6 A;  1PY2 A;  3VEJ A;  4NN5 A;  3FKI D;  1FBX A;  4QIQ A;  5D72 A;  4JR9 A;  2C35 A;  1HUW A;  1Z92 A;  1BP3 A;  2ERJ D;  1HWH A;  3O7Q A;  1N3R A;  5L6Y C;  2JA8 D;  4IKV A;  2B63 D;  3SE4 B;  5KNH I;  2R92 D;  4NE6 B;  3D48 P;  2O6I A;  4J4L C;  4DKC A;  5FHX A;  4ZF7 A;  3LB6 A;  1IS8 A;  3MZG A;  2INT A;  2VUM D;  3Q1S I;  5EQG A;  4DOH A;  2WSE K;  2B91 A;  4YB9 D;  1LK3 A;  1VLK A;  4IKY A;  3OG4 A;  1A7M A;  3WCY I;  4JA3 A;  1NBP A;  4IKX A;  1I1R B;  1PV7 A;  4ZWC A;  2P11 A;  2KZ1 A;  2B8U A;  3PO2 D;  4ZWB A;  2XUT A;  3QWR B;  1F6F A;  4GS7 A;  1HGU A;  3VA2 A;  1PGR A;  1Y6K L;  2JA5 D;  5IYC D;  3INK C;  4PYP A;  1Y6N L;  3BMB A;  1HIK A;  2Q14 A;  1FYH A;  4UVM A;  4LEP A;  3SE3 B;  4ZW9 A;  1TFE A;  1SCF A;  3G6D A;  5IYB D;  4A3L D;  2WSF G;  1ITF A;  4E45 B;  3H3V E;  3PIW A;  1IS7 A;  4DKE A;  3EW3 A;  1ETE A;  3HOU D;  3LW5 G;  1FG9 A;  3TGX B;  4U4T A;  4PS4 A;  1PV6 A;  4A3F D;  4YPG C;  1RHG A;  4I77 Z;  3B0B C;  4OAA A;  1PVH B;  4TPH A;  4QPM A;  3QB7 A;  3NCB A;  4EXP A;  1BUY A;  1LKI A;  1M4A A;  3QAZ A;  1EFU B;  1CSG A;  5A2O A;  4YQX A;  4A93 D;  4XNI A;  1RW5 A;  3DGC L;  2LMS A;  2WSE G;  3DLQ I;  2WSC K;  5C44 D;  4W6V A;  5D59 A;  4D2C A;  1M47 A;  3PO3 D;  1HZI A;  4X51 A;  4A3M D;  1N3T A;  4Q7J A;  3NCC A;  1J7V L;  2CYK A;  3HOX D;  3UEZ E;  4YUE C;  1EKU A;  1HWG A;  3OG6 A;  4E44 B;  3HHR A;  1EXZ A;  5A2N A;  4A3E D;  3PIV A;  4APS A;  5EQH A;  2PSM A;  1Y6M L;  3BES L;  4ZYR A;  1ILK A;  4NN7 A;  5IP9 D;  1RFB A;  1EVS A;  3NCE A;  2KR1 A;  4LDS A;  1M48 A;  3DUH C;  5D6K A;  1B5L A;  2HYM B;  4GC0 A;  2LAG A;  4DRB J; 
#chains in the Genus database with same CATH homology
 1WUR A;  2CFQ A;  2Y5Y A;  5DMZ A;  2V8N A;  4UVM A;  4JRE A;  1A8R A;  4LEP A;  1AIP C;  4TPJ A;  4OH3 A;  1WPL A;  4ZW9 A;  1TFE A;  4TPG A;  4E45 B;  2LNZ A;  1GTP A;  1IS7 A;  4IU9 A;  2CFP A;  1A9C A;  4U4T A;  4U4V A;  5EQI A;  3WDO A;  3VEJ A;  4IKZ A;  2LO0 A;  1PV6 A;  4U4W A;  1FBX A;  4QIQ A;  4D2D A;  3B0B C;  4JR9 A;  4OAA A;  4TPH A;  4IU8 A;  1EL6 A;  4QPM A;  1N3S A;  3O7Q A;  1N3R A;  4YBQ A;  4DRA E;  4IKV A;  4NE3 B;  5C65 A;  1EFU B;  4DU6 A;  4NE6 B;  5A2O A;  4XNI A;  1WM9 A;  1PW4 A;  1IS8 A;  4W6V A;  5D59 A;  4D2C A;  5EQG A;  1N3T A;  4IKW A;  4Q7J A;  4YB9 D;  4XNJ A;  4IKY A;  1WUQ A;  2PN0 A;  4JA3 A;  4IKX A;  4J05 A;  5D58 A;  1PV7 A;  4ZWC A;  4D2B A;  4E44 B;  4Q65 A;  4GBY A;  5A2N A;  2P11 A;  5GXB A;  3O7P A;  4APS A;  5EQH A;  4ZWB A;  2XUT A;  4R8Q A;  4GBZ A;  4ZYR A;  2KR1 A;  4LDS A;  5D6K A;  1FB1 A;  4NE5 B;  4PYP A;  3BMB A;  4GC0 A;  4DRB J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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