2BMUA

Ump kinase from pyrococcus furiosus complexed with its substrate ump and its substrate analog amppnp
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
225
structure length
225
Chain Sequence
MRIVFDIGGSVLVPENPDIDFIKEIAYQLTKVSEDHEVAVVVGGGKLARKYIEVAEKFNSSETFKDFIGIQITRANAMLLIAALREKAYPVVVEDFWEAWKAVQLKKIPVMGGTHPGHTTDAVAALLAEFLKADLLVVITNVDGVYTADPKKDPTAKKIKKMKPEELLEIVGKGIEKAGSSSVIDPLAAKIIARSGIKTIVIGKEDAKDLFRVIKGDHNGTTIEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of Pyrococcus Furiosus Ump Kinase Provides Insight Into Catalysis and Regulation in Microbial Pyrimidine Nucleotide Biosynthesis.
pubmed doi rcsb
molecule tags Transferase
source organism Pyrococcus furiosus
molecule keywords URIDYLATE KINASE
total genus 72
structure length 225
sequence length 225
chains with identical sequence B
ec nomenclature ec 2.7.4.22: UMP kinase.
pdb deposition date 2005-03-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2bmuA00
4A7XA 3L76A 2JJXA 3ZZFA 3U6UA 2BNFA 2W21A 2WE4A 3D40A 2BNEA 4NDRA 2JI5A 1Z9DA 4USJA 3C1MA 2A1FA 2J5TA 1B7BA 1OH9A 2V5HA 2J4LA 3C20A 3K4YA 3S6KA 3QUOA 3AB4A 4A7WA 2J0XA 4NDRB 3QVFA 1GSJA 4NDPA 2IJ9A 2J0WA 1GS5A 3C1NA 4JZ9A 2HMFA 4JZ8A 3TVIA 2RD5A 2BRXA 3ZZIA 3K56A 3QVHA 3EK6A 3QURA 1YBDA 2WXBA 3WWMA 3ZZGA 2E9YA 4NDPB 4Q1TA 3K52A 2BTYA 3WWNA 4F6TB 3LL5A 2J5VA 2V4YA 3B8GA 3L86A 3KZFA 2X2WA 4AXSA 2BRIA 3QUNA 4F6TA 3AAWA 2AKOA 2R8VA 2WE5A 2AP9A 4NDOB 1OHAA 1E19A 3S6HA 3ZZHA 2J4KA 1OHBA 4NDQA 2JJ4A 3D2MA 3NWYA 2BNDA 3S6GA 4NDOA 3LKKA 2BUFA 2R98A 4KZTA 2OGXA 3K4OA 3LL9A 4I49A 4NDQB 3D41A 3D2PA 3T7BA 2CDQA 2J4JA 2VA1A 2BMUA 3EK5A 4AB7A 2OGXB 4JZ7A 3AB2A 4OLCA
chains in the Genus database with same CATH superfamily
4A7XA 3L76A 2JJXA 3ZZFA 3U6UA 2BNFA 2W21A 2WE4A 3D40A 2BNEA 4NDRA 2JI5A 1Z9DA 4USJA 3C1MA 2A1FA 2J5TA 1B7BA 1OH9A 2V5HA 2J4LA 3C20A 3K4YA 3S6KA 3QUOA 3AB4A 4A7WA 2J0XA 4NDRB 3QVFA 1GSJA 4NDPA 2IJ9A 2J0WA 1GS5A 3C1NA 4JZ9A 2HMFA 4JZ8A 3TVIA 2RD5A 2BRXA 3ZZIA 3K56A 3QVHA 3EK6A 3QURA 1YBDA 2WXBA 3WWMA 3ZZGA 2E9YA 4NDPB 4Q1TA 3K52A 2BTYA 3WWNA 4F6TB 3LL5A 2J5VA 2V4YA 3B8GA 3L86A 3KZFA 2X2WA 4AXSA 2BRIA 3QUNA 4F6TA 3AAWA 2AKOA 2R8VA 2WE5A 2AP9A 4NDOB 1OHAA 1E19A 3S6HA 3ZZHA 2J4KA 1OHBA 4NDQA 2JJ4A 3D2MA 3NWYA 2BNDA 3S6GA 4NDOA 3LKKA 2BUFA 2R98A 4KZTA 2OGXA 3K4OA 3LL9A 4I49A 4NDQB 3D41A 3D2PA 3T7BA 2CDQA 2J4JA 2VA1A 2BMUA 3EK5A 4AB7A 2OGXB 4JZ7A 3AB2A 4OLCA
chains in the Genus database with same CATH topology
4A7XA 3L76A 2JJXA 3ZZFA 3U6UA 2BNFA 2W21A 2WE4A 3D40A 2BNEA 4NDRA 2JI5A 1Z9DA 4USJA 3C1MA 2A1FA 2J5TA 1B7BA 1OH9A 2V5HA 2J4LA 3C20A 3K4YA 3S6KA 3QUOA 3AB4A 4A7WA 2J0XA 4NDRB 3QVFA 1GSJA 4NDPA 2IJ9A 2J0WA 1GS5A 3C1NA 4JZ9A 2HMFA 4JZ8A 3TVIA 2RD5A 2BRXA 3ZZIA 3K56A 3QVHA 3EK6A 3QURA 1YBDA 2WXBA 3WWMA 3ZZGA 2E9YA 4NDPB 4Q1TA 3K52A 2BTYA 3WWNA 4F6TB 3LL5A 2J5VA 2V4YA 3B8GA 3L86A 3KZFA 2X2WA 4AXSA 2BRIA 3QUNA 4F6TA 3AAWA 2AKOA 2R8VA 2WE5A 2AP9A 4NDOB 1OHAA 1E19A 3S6HA 3ZZHA 2J4KA 1OHBA 4NDQA 2JJ4A 3D2MA 3NWYA 2BNDA 3S6GA 4NDOA 3LKKA 2BUFA 2R98A 4KZTA 2OGXA 3K4OA 3LL9A 4I49A 4NDQB 3D41A 3D2PA 3T7BA 2CDQA 2J4JA 2VA1A 2BMUA 3EK5A 4AB7A 2OGXB 4JZ7A 3AB2A 4OLCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A7X A;  3L76 A;  2JJX A;  3ZZF A;  3U6U A;  2BNF A;  2W21 A;  2WE4 A;  3D40 A;  2BNE A;  4NDR A;  2JI5 A;  1Z9D A;  4USJ A;  3C1M A;  2A1F A;  2J5T A;  1B7B A;  1OH9 A;  2V5H A;  2J4L A;  3C20 A;  3K4Y A;  3S6K A;  3QUO A;  3AB4 A;  4A7W A;  2J0X A;  4NDR B;  3QVF A;  1GSJ A;  4NDP A;  2IJ9 A;  2J0W A;  1GS5 A;  3C1N A;  4JZ9 A;  2HMF A;  4JZ8 A;  3TVI A;  2RD5 A;  2BRX A;  3ZZI A;  3K56 A;  3QVH A;  3EK6 A;  3QUR A;  1YBD A;  2WXB A;  3WWM A;  3ZZG A;  2E9Y A;  4NDP B;  4Q1T A;  3K52 A;  2BTY A;  3WWN A;  4F6T B;  3LL5 A;  2J5V A;  2V4Y A;  3B8G A;  3L86 A;  3KZF A;  2X2W A;  4AXS A;  2BRI A;  3QUN A;  4F6T A;  3AAW A;  2AKO A;  2R8V A;  2WE5 A;  2AP9 A;  4NDO B;  1OHA A;  1E19 A;  3S6H A;  3ZZH A;  2J4K A;  1OHB A;  4NDQ A;  2JJ4 A;  3D2M A;  3NWY A;  2BND A;  3S6G A;  4NDO A;  3LKK A;  2BUF A;  2R98 A;  4KZT A;  2OGX A;  3K4O A;  3LL9 A;  4I49 A;  4NDQ B;  3D41 A;  3D2P A;  3T7B A;  2CDQ A;  2J4J A;  2VA1 A;  2BMU A;  3EK5 A;  4AB7 A;  2OGX B;  4JZ7 A;  3AB2 A;  4OLC A; 
#chains in the Genus database with same CATH topology
 4A7X A;  3L76 A;  2JJX A;  3ZZF A;  3U6U A;  2BNF A;  2W21 A;  2WE4 A;  3D40 A;  2BNE A;  4NDR A;  2JI5 A;  1Z9D A;  4USJ A;  3C1M A;  2A1F A;  2J5T A;  1B7B A;  1OH9 A;  2V5H A;  2J4L A;  3C20 A;  3K4Y A;  3S6K A;  3QUO A;  3AB4 A;  4A7W A;  2J0X A;  4NDR B;  3QVF A;  1GSJ A;  4NDP A;  2IJ9 A;  2J0W A;  1GS5 A;  3C1N A;  4JZ9 A;  2HMF A;  4JZ8 A;  3TVI A;  2RD5 A;  2BRX A;  3ZZI A;  3K56 A;  3QVH A;  3EK6 A;  3QUR A;  1YBD A;  2WXB A;  3WWM A;  3ZZG A;  2E9Y A;  4NDP B;  4Q1T A;  3K52 A;  2BTY A;  3WWN A;  4F6T B;  3LL5 A;  2J5V A;  2V4Y A;  3B8G A;  3L86 A;  3KZF A;  2X2W A;  4AXS A;  2BRI A;  3QUN A;  4F6T A;  3AAW A;  2AKO A;  2R8V A;  2WE5 A;  2AP9 A;  4NDO B;  1OHA A;  1E19 A;  3S6H A;  3ZZH A;  2J4K A;  1OHB A;  4NDQ A;  2JJ4 A;  3D2M A;  3NWY A;  2BND A;  3S6G A;  4NDO A;  3LKK A;  2BUF A;  2R98 A;  4KZT A;  2OGX A;  3K4O A;  3LL9 A;  4I49 A;  4NDQ B;  3D41 A;  3D2P A;  3T7B A;  2CDQ A;  2J4J A;  2VA1 A;  2BMU A;  3EK5 A;  4AB7 A;  2OGX B;  4JZ7 A;  3AB2 A;  4OLC A; 
#chains in the Genus database with same CATH homology
 4A7X A;  3L76 A;  2JJX A;  3ZZF A;  3U6U A;  2BNF A;  2W21 A;  2WE4 A;  3D40 A;  2BNE A;  4NDR A;  2JI5 A;  1Z9D A;  4USJ A;  3C1M A;  2A1F A;  2J5T A;  1B7B A;  1OH9 A;  2V5H A;  2J4L A;  3C20 A;  3K4Y A;  3S6K A;  3QUO A;  3AB4 A;  4A7W A;  2J0X A;  4NDR B;  3QVF A;  1GSJ A;  4NDP A;  2IJ9 A;  2J0W A;  1GS5 A;  3C1N A;  4JZ9 A;  2HMF A;  4JZ8 A;  3TVI A;  2RD5 A;  2BRX A;  3ZZI A;  3K56 A;  3QVH A;  3EK6 A;  3QUR A;  1YBD A;  2WXB A;  3WWM A;  3ZZG A;  2E9Y A;  4NDP B;  4Q1T A;  3K52 A;  2BTY A;  3WWN A;  4F6T B;  3LL5 A;  2J5V A;  2V4Y A;  3B8G A;  3L86 A;  3KZF A;  2X2W A;  4AXS A;  2BRI A;  3QUN A;  4F6T A;  3AAW A;  2AKO A;  2R8V A;  2WE5 A;  2AP9 A;  4NDO B;  1OHA A;  1E19 A;  3S6H A;  3ZZH A;  2J4K A;  1OHB A;  4NDQ A;  2JJ4 A;  3D2M A;  3NWY A;  2BND A;  3S6G A;  4NDO A;  3LKK A;  2BUF A;  2R98 A;  4KZT A;  2OGX A;  3K4O A;  3LL9 A;  4I49 A;  4NDQ B;  3D41 A;  3D2P A;  3T7B A;  2CDQ A;  2J4J A;  2VA1 A;  2BMU A;  3EK5 A;  4AB7 A;  2OGX B;  4JZ7 A;  3AB2 A;  4OLC A; 
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