2BMUA

Ump kinase from pyrococcus furiosus complexed with its substrate ump and its substrate analog amppnp
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
225
structure length
225
Chain Sequence
MRIVFDIGGSVLVPENPDIDFIKEIAYQLTKVSEDHEVAVVVGGGKLARKYIEVAEKFNSSETFKDFIGIQITRANAMLLIAALREKAYPVVVEDFWEAWKAVQLKKIPVMGGTHPGHTTDAVAALLAEFLKADLLVVITNVDGVYTADPKKDPTAKKIKKMKPEELLEIVGKGIEKAGSSSVIDPLAAKIIARSGIKTIVIGKEDAKDLFRVIKGDHNGTTIEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of Pyrococcus Furiosus Ump Kinase Provides Insight Into Catalysis and Regulation in Microbial Pyrimidine Nucleotide Biosynthesis.
pubmed doi rcsb
molecule tags Transferase
source organism Pyrococcus furiosus
molecule keywords URIDYLATE KINASE
total genus 72
structure length 225
sequence length 225
chains with identical sequence B
ec nomenclature ec 2.7.4.22: UMP kinase.
pdb deposition date 2005-03-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2bmuA00
3C1MA 2OGXA 4USJA 3QUOA 2WE5A 3LL5A 2IJ9A 3B8GA 4OLCA 2R8VA 3S6GA 3QUNA 3ZZHA 1GSJA 3AB4A 3EK6A 3TVIA 3D40A 2WXBA 2CDQA 3QVHA 2BRIA 3QVFA 4NDOA 2J5VA 4JZ9A 2AKOA 2J5TA 2J4KA 3C1NA 3S6KA 1GS5A 2BRXA 3S6HA 4NDOB 3WWNA 2V4YA 2A1FA 2J0WA 1OHAA 4A7XA 3WWMA 3C20A 3KZFA 3AB2A 2BNDA 4NDQA 2JJ4A 3U6UA 1OH9A 3ZZGA 4KZTA 1Z9DA 2VA1A 3QURA 2BMUA 2JI5A 4NDQB 2R98A 2BNFA 3ZZIA 4F6TA 3D41A 2V5HA 3LL9A 2W21A 4NDPA 2J0XA 4Q1TA 4I49A 3L86A 4NDRA 4AXSA 2X2WA 4F6TB 2BNEA 3T7BA 3D2PA 4JZ7A 1B7BA 2WE4A 4NDPB 2RD5A 4AB7A 2BTYA 3ZZFA 4A7WA 4NDRB 2BUFA 3K4OA 3LKKA 2HMFA 2JJXA 2J4JA 2OGXB 3L76A 3K56A 4JZ8A 3K52A 3NWYA 3D2MA 2E9YA 2AP9A 1YBDA 1E19A 3AAWA 1OHBA 3EK5A 3K4YA 2J4LA
chains in the Genus database with same CATH superfamily
3C1MA 2OGXA 4USJA 3QUOA 2WE5A 3LL5A 2IJ9A 3B8GA 4OLCA 2R8VA 3S6GA 3QUNA 3ZZHA 1GSJA 3AB4A 3EK6A 3TVIA 3D40A 2WXBA 2CDQA 3QVHA 2BRIA 3QVFA 4NDOA 2J5VA 4JZ9A 2AKOA 2J5TA 2J4KA 3C1NA 3S6KA 1GS5A 2BRXA 3S6HA 4NDOB 3WWNA 2V4YA 2A1FA 2J0WA 1OHAA 4A7XA 3WWMA 3C20A 3KZFA 3AB2A 2BNDA 4NDQA 2JJ4A 3U6UA 1OH9A 3ZZGA 4KZTA 1Z9DA 2VA1A 3QURA 2BMUA 2JI5A 4NDQB 2R98A 2BNFA 3ZZIA 4F6TA 3D41A 2V5HA 3LL9A 2W21A 4NDPA 2J0XA 4Q1TA 4I49A 3L86A 4NDRA 4AXSA 2X2WA 4F6TB 2BNEA 3T7BA 3D2PA 4JZ7A 1B7BA 2WE4A 4NDPB 2RD5A 4AB7A 2BTYA 3ZZFA 4A7WA 4NDRB 2BUFA 3K4OA 3LKKA 2HMFA 2JJXA 2J4JA 2OGXB 3L76A 3K56A 4JZ8A 3K52A 3NWYA 3D2MA 2E9YA 2AP9A 1YBDA 1E19A 3AAWA 1OHBA 3EK5A 3K4YA 2J4LA
chains in the Genus database with same CATH topology
3C1MA 2OGXA 4USJA 3QUOA 2WE5A 3LL5A 2IJ9A 3B8GA 4OLCA 2R8VA 3S6GA 3QUNA 3ZZHA 1GSJA 3AB4A 3EK6A 3TVIA 3D40A 2WXBA 2CDQA 3QVHA 2BRIA 3QVFA 4NDOA 2J5VA 4JZ9A 2AKOA 2J5TA 2J4KA 3C1NA 3S6KA 1GS5A 2BRXA 3S6HA 4NDOB 3WWNA 2V4YA 2A1FA 2J0WA 1OHAA 4A7XA 3WWMA 3C20A 3KZFA 3AB2A 2BNDA 4NDQA 2JJ4A 3U6UA 1OH9A 3ZZGA 4KZTA 1Z9DA 2VA1A 3QURA 2BMUA 2JI5A 4NDQB 2R98A 2BNFA 3ZZIA 4F6TA 3D41A 2V5HA 3LL9A 2W21A 4NDPA 2J0XA 4Q1TA 4I49A 3L86A 4NDRA 4AXSA 2X2WA 4F6TB 2BNEA 3T7BA 3D2PA 4JZ7A 1B7BA 2WE4A 4NDPB 2RD5A 4AB7A 2BTYA 3ZZFA 4A7WA 4NDRB 2BUFA 3K4OA 3LKKA 2HMFA 2JJXA 2J4JA 2OGXB 3L76A 3K56A 4JZ8A 3K52A 3NWYA 3D2MA 2E9YA 2AP9A 1YBDA 1E19A 3AAWA 1OHBA 3EK5A 3K4YA 2J4LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C1M A;  2OGX A;  4USJ A;  3QUO A;  2WE5 A;  3LL5 A;  2IJ9 A;  3B8G A;  4OLC A;  2R8V A;  3S6G A;  3QUN A;  3ZZH A;  1GSJ A;  3AB4 A;  3EK6 A;  3TVI A;  3D40 A;  2WXB A;  2CDQ A;  3QVH A;  2BRI A;  3QVF A;  4NDO A;  2J5V A;  4JZ9 A;  2AKO A;  2J5T A;  2J4K A;  3C1N A;  3S6K A;  1GS5 A;  2BRX A;  3S6H A;  4NDO B;  3WWN A;  2V4Y A;  2A1F A;  2J0W A;  1OHA A;  4A7X A;  3WWM A;  3C20 A;  3KZF A;  3AB2 A;  2BND A;  4NDQ A;  2JJ4 A;  3U6U A;  1OH9 A;  3ZZG A;  4KZT A;  1Z9D A;  2VA1 A;  3QUR A;  2BMU A;  2JI5 A;  4NDQ B;  2R98 A;  2BNF A;  3ZZI A;  4F6T A;  3D41 A;  2V5H A;  3LL9 A;  2W21 A;  4NDP A;  2J0X A;  4Q1T A;  4I49 A;  3L86 A;  4NDR A;  4AXS A;  2X2W A;  4F6T B;  2BNE A;  3T7B A;  3D2P A;  4JZ7 A;  1B7B A;  2WE4 A;  4NDP B;  2RD5 A;  4AB7 A;  2BTY A;  3ZZF A;  4A7W A;  4NDR B;  2BUF A;  3K4O A;  3LKK A;  2HMF A;  2JJX A;  2J4J A;  2OGX B;  3L76 A;  3K56 A;  4JZ8 A;  3K52 A;  3NWY A;  3D2M A;  2E9Y A;  2AP9 A;  1YBD A;  1E19 A;  3AAW A;  1OHB A;  3EK5 A;  3K4Y A;  2J4L A; 
#chains in the Genus database with same CATH topology
 3C1M A;  2OGX A;  4USJ A;  3QUO A;  2WE5 A;  3LL5 A;  2IJ9 A;  3B8G A;  4OLC A;  2R8V A;  3S6G A;  3QUN A;  3ZZH A;  1GSJ A;  3AB4 A;  3EK6 A;  3TVI A;  3D40 A;  2WXB A;  2CDQ A;  3QVH A;  2BRI A;  3QVF A;  4NDO A;  2J5V A;  4JZ9 A;  2AKO A;  2J5T A;  2J4K A;  3C1N A;  3S6K A;  1GS5 A;  2BRX A;  3S6H A;  4NDO B;  3WWN A;  2V4Y A;  2A1F A;  2J0W A;  1OHA A;  4A7X A;  3WWM A;  3C20 A;  3KZF A;  3AB2 A;  2BND A;  4NDQ A;  2JJ4 A;  3U6U A;  1OH9 A;  3ZZG A;  4KZT A;  1Z9D A;  2VA1 A;  3QUR A;  2BMU A;  2JI5 A;  4NDQ B;  2R98 A;  2BNF A;  3ZZI A;  4F6T A;  3D41 A;  2V5H A;  3LL9 A;  2W21 A;  4NDP A;  2J0X A;  4Q1T A;  4I49 A;  3L86 A;  4NDR A;  4AXS A;  2X2W A;  4F6T B;  2BNE A;  3T7B A;  3D2P A;  4JZ7 A;  1B7B A;  2WE4 A;  4NDP B;  2RD5 A;  4AB7 A;  2BTY A;  3ZZF A;  4A7W A;  4NDR B;  2BUF A;  3K4O A;  3LKK A;  2HMF A;  2JJX A;  2J4J A;  2OGX B;  3L76 A;  3K56 A;  4JZ8 A;  3K52 A;  3NWY A;  3D2M A;  2E9Y A;  2AP9 A;  1YBD A;  1E19 A;  3AAW A;  1OHB A;  3EK5 A;  3K4Y A;  2J4L A; 
#chains in the Genus database with same CATH homology
 3C1M A;  2OGX A;  4USJ A;  3QUO A;  2WE5 A;  3LL5 A;  2IJ9 A;  3B8G A;  4OLC A;  2R8V A;  3S6G A;  3QUN A;  3ZZH A;  1GSJ A;  3AB4 A;  3EK6 A;  3TVI A;  3D40 A;  2WXB A;  2CDQ A;  3QVH A;  2BRI A;  3QVF A;  4NDO A;  2J5V A;  4JZ9 A;  2AKO A;  2J5T A;  2J4K A;  3C1N A;  3S6K A;  1GS5 A;  2BRX A;  3S6H A;  4NDO B;  3WWN A;  2V4Y A;  2A1F A;  2J0W A;  1OHA A;  4A7X A;  3WWM A;  3C20 A;  3KZF A;  3AB2 A;  2BND A;  4NDQ A;  2JJ4 A;  3U6U A;  1OH9 A;  3ZZG A;  4KZT A;  1Z9D A;  2VA1 A;  3QUR A;  2BMU A;  2JI5 A;  4NDQ B;  2R98 A;  2BNF A;  3ZZI A;  4F6T A;  3D41 A;  2V5H A;  3LL9 A;  2W21 A;  4NDP A;  2J0X A;  4Q1T A;  4I49 A;  3L86 A;  4NDR A;  4AXS A;  2X2W A;  4F6T B;  2BNE A;  3T7B A;  3D2P A;  4JZ7 A;  1B7B A;  2WE4 A;  4NDP B;  2RD5 A;  4AB7 A;  2BTY A;  3ZZF A;  4A7W A;  4NDR B;  2BUF A;  3K4O A;  3LKK A;  2HMF A;  2JJX A;  2J4J A;  2OGX B;  3L76 A;  3K56 A;  4JZ8 A;  3K52 A;  3NWY A;  3D2M A;  2E9Y A;  2AP9 A;  1YBD A;  1E19 A;  3AAW A;  1OHB A;  3EK5 A;  3K4Y A;  2J4L A; 
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similar chains in the pdb database (?% sequence similarity)

 
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