2BMUA

Ump kinase from pyrococcus furiosus complexed with its substrate ump and its substrate analog amppnp
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
225
structure length
225
Chain Sequence
MRIVFDIGGSVLVPENPDIDFIKEIAYQLTKVSEDHEVAVVVGGGKLARKYIEVAEKFNSSETFKDFIGIQITRANAMLLIAALREKAYPVVVEDFWEAWKAVQLKKIPVMGGTHPGHTTDAVAALLAEFLKADLLVVITNVDGVYTADPKKDPTAKKIKKMKPEELLEIVGKGIEKAGSSSVIDPLAAKIIARSGIKTIVIGKEDAKDLFRVIKGDHNGTTIEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Pyrococcus furiosus
publication title The Crystal Structure of Pyrococcus Furiosus Ump Kinase Provides Insight Into Catalysis and Regulation in Microbial Pyrimidine Nucleotide Biosynthesis.
pubmed doi rcsb
molecule keywords URIDYLATE KINASE
total genus 72
structure length 225
sequence length 225
chains with identical sequence B
ec nomenclature ec 2.7.4.22: UMP kinase.
pdb deposition date 2005-03-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2bmuA00
4NDOB 4KZTA 1OHBA 3S6KA 4A7XA 2BNFA 1YBDA 4NDQB 2BTYA 3C20A 4AB7A 2OGXA 2V4YA 3TVIA 2J4JA 2E9YA 2W21A 2WE4A 2WE5A 3L86A 1GSJA 3KZFA 2J4LA 4NDPB 2J4KA 1B7BA 2BUFA 3NWYA 3AAWA 2VA1A 2R8VA 4F6TA 3LKKA 4Q1TA 3S6GA 1GS5A 3D2MA 4NDRB 2RD5A 3EK6A 2BRIA 2J0XA 2BMUA 1OH9A 3WWMA 2JJXA 3S6HA 3EK5A 4NDOA 3C1MA 2J0WA 2HMFA 3D2PA 3WWNA 3QUOA 3C1NA 3K52A 3ZZFA 4JZ7A 3K56A 1OHAA 4NDQA 4JZ9A 3QUNA 3ZZHA 2JJ4A 2WXBA 3K4OA 4OLCA 3ZZIA 2R98A 4NDPA 2AP9A 3K4YA 2A1FA 2OGXB 2JI5A 3D41A 3AB2A 4NDRA 3D40A 3ZZGA 1Z9DA 4I49A 4AXSA 2IJ9A 3L76A 2BRXA 2J5TA 4USJA 2BNEA 3LL9A 2X2WA 3LL5A 4F6TB 3B8GA 3QURA 2V5HA 1E19A 2J5VA 3AB4A 2AKOA 3QVHA 4A7WA 3U6UA 3QVFA 2BNDA 2CDQA 4JZ8A 3T7BA
chains in the Genus database with same CATH superfamily
4NDOB 4KZTA 1OHBA 3S6KA 4A7XA 2BNFA 1YBDA 4NDQB 2BTYA 3C20A 4AB7A 2OGXA 2V4YA 3TVIA 2J4JA 2E9YA 2W21A 2WE4A 2WE5A 3L86A 1GSJA 3KZFA 2J4LA 4NDPB 2J4KA 1B7BA 2BUFA 3NWYA 3AAWA 2VA1A 2R8VA 4F6TA 3LKKA 4Q1TA 3S6GA 1GS5A 3D2MA 4NDRB 2RD5A 3EK6A 2BRIA 2J0XA 2BMUA 1OH9A 3WWMA 2JJXA 3S6HA 3EK5A 4NDOA 3C1MA 2J0WA 2HMFA 3D2PA 3WWNA 3QUOA 3C1NA 3K52A 3ZZFA 4JZ7A 3K56A 1OHAA 4NDQA 4JZ9A 3QUNA 3ZZHA 2JJ4A 2WXBA 3K4OA 4OLCA 3ZZIA 2R98A 4NDPA 2AP9A 3K4YA 2A1FA 2OGXB 2JI5A 3D41A 3AB2A 4NDRA 3D40A 3ZZGA 1Z9DA 4I49A 4AXSA 2IJ9A 3L76A 2BRXA 2J5TA 4USJA 2BNEA 3LL9A 2X2WA 3LL5A 4F6TB 3B8GA 3QURA 2V5HA 1E19A 2J5VA 3AB4A 2AKOA 3QVHA 4A7WA 3U6UA 3QVFA 2BNDA 2CDQA 4JZ8A 3T7BA
chains in the Genus database with same CATH topology
4NDOB 4KZTA 1OHBA 3S6KA 4A7XA 2BNFA 1YBDA 4NDQB 2BTYA 3C20A 4AB7A 2OGXA 2V4YA 3TVIA 2J4JA 2E9YA 2W21A 2WE4A 2WE5A 3L86A 1GSJA 3KZFA 2J4LA 4NDPB 2J4KA 1B7BA 2BUFA 3NWYA 3AAWA 2VA1A 2R8VA 4F6TA 3LKKA 4Q1TA 3S6GA 1GS5A 3D2MA 4NDRB 2RD5A 3EK6A 2BRIA 2J0XA 2BMUA 1OH9A 3WWMA 2JJXA 3S6HA 3EK5A 4NDOA 3C1MA 2J0WA 2HMFA 3D2PA 3WWNA 3QUOA 3C1NA 3K52A 3ZZFA 4JZ7A 3K56A 1OHAA 4NDQA 4JZ9A 3QUNA 3ZZHA 2JJ4A 2WXBA 3K4OA 4OLCA 3ZZIA 2R98A 4NDPA 2AP9A 3K4YA 2A1FA 2OGXB 2JI5A 3D41A 3AB2A 4NDRA 3D40A 3ZZGA 1Z9DA 4I49A 4AXSA 2IJ9A 3L76A 2BRXA 2J5TA 4USJA 2BNEA 3LL9A 2X2WA 3LL5A 4F6TB 3B8GA 3QURA 2V5HA 1E19A 2J5VA 3AB4A 2AKOA 3QVHA 4A7WA 3U6UA 3QVFA 2BNDA 2CDQA 4JZ8A 3T7BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NDO B;  4KZT A;  1OHB A;  3S6K A;  4A7X A;  2BNF A;  1YBD A;  4NDQ B;  2BTY A;  3C20 A;  4AB7 A;  2OGX A;  2V4Y A;  3TVI A;  2J4J A;  2E9Y A;  2W21 A;  2WE4 A;  2WE5 A;  3L86 A;  1GSJ A;  3KZF A;  2J4L A;  4NDP B;  2J4K A;  1B7B A;  2BUF A;  3NWY A;  3AAW A;  2VA1 A;  2R8V A;  4F6T A;  3LKK A;  4Q1T A;  3S6G A;  1GS5 A;  3D2M A;  4NDR B;  2RD5 A;  3EK6 A;  2BRI A;  2J0X A;  2BMU A;  1OH9 A;  3WWM A;  2JJX A;  3S6H A;  3EK5 A;  4NDO A;  3C1M A;  2J0W A;  2HMF A;  3D2P A;  3WWN A;  3QUO A;  3C1N A;  3K52 A;  3ZZF A;  4JZ7 A;  3K56 A;  1OHA A;  4NDQ A;  4JZ9 A;  3QUN A;  3ZZH A;  2JJ4 A;  2WXB A;  3K4O A;  4OLC A;  3ZZI A;  2R98 A;  4NDP A;  2AP9 A;  3K4Y A;  2A1F A;  2OGX B;  2JI5 A;  3D41 A;  3AB2 A;  4NDR A;  3D40 A;  3ZZG A;  1Z9D A;  4I49 A;  4AXS A;  2IJ9 A;  3L76 A;  2BRX A;  2J5T A;  4USJ A;  2BNE A;  3LL9 A;  2X2W A;  3LL5 A;  4F6T B;  3B8G A;  3QUR A;  2V5H A;  1E19 A;  2J5V A;  3AB4 A;  2AKO A;  3QVH A;  4A7W A;  3U6U A;  3QVF A;  2BND A;  2CDQ A;  4JZ8 A;  3T7B A; 
#chains in the Genus database with same CATH topology
 4NDO B;  4KZT A;  1OHB A;  3S6K A;  4A7X A;  2BNF A;  1YBD A;  4NDQ B;  2BTY A;  3C20 A;  4AB7 A;  2OGX A;  2V4Y A;  3TVI A;  2J4J A;  2E9Y A;  2W21 A;  2WE4 A;  2WE5 A;  3L86 A;  1GSJ A;  3KZF A;  2J4L A;  4NDP B;  2J4K A;  1B7B A;  2BUF A;  3NWY A;  3AAW A;  2VA1 A;  2R8V A;  4F6T A;  3LKK A;  4Q1T A;  3S6G A;  1GS5 A;  3D2M A;  4NDR B;  2RD5 A;  3EK6 A;  2BRI A;  2J0X A;  2BMU A;  1OH9 A;  3WWM A;  2JJX A;  3S6H A;  3EK5 A;  4NDO A;  3C1M A;  2J0W A;  2HMF A;  3D2P A;  3WWN A;  3QUO A;  3C1N A;  3K52 A;  3ZZF A;  4JZ7 A;  3K56 A;  1OHA A;  4NDQ A;  4JZ9 A;  3QUN A;  3ZZH A;  2JJ4 A;  2WXB A;  3K4O A;  4OLC A;  3ZZI A;  2R98 A;  4NDP A;  2AP9 A;  3K4Y A;  2A1F A;  2OGX B;  2JI5 A;  3D41 A;  3AB2 A;  4NDR A;  3D40 A;  3ZZG A;  1Z9D A;  4I49 A;  4AXS A;  2IJ9 A;  3L76 A;  2BRX A;  2J5T A;  4USJ A;  2BNE A;  3LL9 A;  2X2W A;  3LL5 A;  4F6T B;  3B8G A;  3QUR A;  2V5H A;  1E19 A;  2J5V A;  3AB4 A;  2AKO A;  3QVH A;  4A7W A;  3U6U A;  3QVF A;  2BND A;  2CDQ A;  4JZ8 A;  3T7B A; 
#chains in the Genus database with same CATH homology
 4NDO B;  4KZT A;  1OHB A;  3S6K A;  4A7X A;  2BNF A;  1YBD A;  4NDQ B;  2BTY A;  3C20 A;  4AB7 A;  2OGX A;  2V4Y A;  3TVI A;  2J4J A;  2E9Y A;  2W21 A;  2WE4 A;  2WE5 A;  3L86 A;  1GSJ A;  3KZF A;  2J4L A;  4NDP B;  2J4K A;  1B7B A;  2BUF A;  3NWY A;  3AAW A;  2VA1 A;  2R8V A;  4F6T A;  3LKK A;  4Q1T A;  3S6G A;  1GS5 A;  3D2M A;  4NDR B;  2RD5 A;  3EK6 A;  2BRI A;  2J0X A;  2BMU A;  1OH9 A;  3WWM A;  2JJX A;  3S6H A;  3EK5 A;  4NDO A;  3C1M A;  2J0W A;  2HMF A;  3D2P A;  3WWN A;  3QUO A;  3C1N A;  3K52 A;  3ZZF A;  4JZ7 A;  3K56 A;  1OHA A;  4NDQ A;  4JZ9 A;  3QUN A;  3ZZH A;  2JJ4 A;  2WXB A;  3K4O A;  4OLC A;  3ZZI A;  2R98 A;  4NDP A;  2AP9 A;  3K4Y A;  2A1F A;  2OGX B;  2JI5 A;  3D41 A;  3AB2 A;  4NDR A;  3D40 A;  3ZZG A;  1Z9D A;  4I49 A;  4AXS A;  2IJ9 A;  3L76 A;  2BRX A;  2J5T A;  4USJ A;  2BNE A;  3LL9 A;  2X2W A;  3LL5 A;  4F6T B;  3B8G A;  3QUR A;  2V5H A;  1E19 A;  2J5V A;  3AB4 A;  2AKO A;  3QVH A;  4A7W A;  3U6U A;  3QVF A;  2BND A;  2CDQ A;  4JZ8 A;  3T7B A; 
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