2J4KA

Crystal structure of uridylate kinase from sulfolobus solfataricus in complex with ump to 2.2 angstrom resolution
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
226
structure length
207
Chain Sequence
MNIILKISGKFFDEDNVDNLIVLRQSIKELADNGFRVGIVTGGGSTARRYIKLAREIGIGEAYLDLLGIWASRLNAYLVMFSLQDLAYMHVPQSLEEFIQDWSHGKVVVTGGFQPGQSTAAVAALVAEASSSKTLVVATNVDGVYEKDPRIYADVKLIPHLTTQDLRKILLLDPLAIKIVERSKIRVIVMNYRKLNRIEVSSIIEPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Enzymatic Investigation of the Sulfolobus Solfataricus Uridylate Kinase Shows Competitive Utp Inhibition and the Lack of GTP Stimulation
pubmed doi rcsb
source organism Sulfolobus solfataricus
molecule tags Transferase
molecule keywords URIDYLATE KINASE
total genus 68
structure length 207
sequence length 226
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.7.4.22: UMP kinase.
pdb deposition date 2006-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j4kA00
3AB2A 3EK6A 3S6HA 2OGXA 2J4KA 2X2WA 3B8GA 4JZ7A 3D2MA 4NDPA 2R8VA 2BNEA 3K4OA 2WXBA 3L76A 2JJXA 4NDRB 2BUFA 3S6KA 4NDOA 3QUOA 2R98A 4NDOB 2J0XA 2RD5A 2OGXB 4NDQB 4AB7A 3L86A 2J0WA 3EK5A 4I49A 3AAWA 1OHBA 4F6TB 3WWNA 4NDRA 2J5VA 2A1FA 2BNFA 2CDQA 2W21A 2BRIA 1Z9DA 3WWMA 1B7BA 2J4JA 3QURA 2BMUA 3T7BA 3C1NA 4JZ8A 1OH9A 2V4YA 3TVIA 2J5TA 2BTYA 1YBDA 2WE5A 4KZTA 3NWYA 3QVHA 4JZ9A 2J4LA 2VA1A 2JI5A 3D40A 2IJ9A 1GSJA 1OHAA 4A7XA 3QVFA 3ZZHA 4USJA 3LKKA 4F6TA 3ZZFA 2AKOA 3LL5A 3QUNA 3LL9A 2HMFA 3K56A 3ZZGA 4Q1TA 2WE4A 3U6UA 3D2PA 2AP9A 2E9YA 3C20A 3C1MA 3S6GA 3KZFA 3D41A 4NDQA 2BNDA 4NDPB 2BRXA 4OLCA 3AB4A 4AXSA 3K52A 1GS5A 3K4YA 4A7WA 2V5HA 2JJ4A 3ZZIA 1E19A
chains in the Genus database with same CATH superfamily
3AB2A 3EK6A 3S6HA 2OGXA 2J4KA 2X2WA 3B8GA 4JZ7A 3D2MA 4NDPA 2R8VA 2BNEA 3K4OA 2WXBA 3L76A 2JJXA 4NDRB 2BUFA 3S6KA 4NDOA 3QUOA 2R98A 4NDOB 2J0XA 2RD5A 2OGXB 4NDQB 4AB7A 3L86A 2J0WA 3EK5A 4I49A 3AAWA 1OHBA 4F6TB 3WWNA 4NDRA 2J5VA 2A1FA 2BNFA 2CDQA 2W21A 2BRIA 1Z9DA 3WWMA 1B7BA 2J4JA 3QURA 2BMUA 3T7BA 3C1NA 4JZ8A 1OH9A 2V4YA 3TVIA 2J5TA 2BTYA 1YBDA 2WE5A 4KZTA 3NWYA 3QVHA 4JZ9A 2J4LA 2VA1A 2JI5A 3D40A 2IJ9A 1GSJA 1OHAA 4A7XA 3QVFA 3ZZHA 4USJA 3LKKA 4F6TA 3ZZFA 2AKOA 3LL5A 3QUNA 3LL9A 2HMFA 3K56A 3ZZGA 4Q1TA 2WE4A 3U6UA 3D2PA 2AP9A 2E9YA 3C20A 3C1MA 3S6GA 3KZFA 3D41A 4NDQA 2BNDA 4NDPB 2BRXA 4OLCA 3AB4A 4AXSA 3K52A 1GS5A 3K4YA 4A7WA 2V5HA 2JJ4A 3ZZIA 1E19A
chains in the Genus database with same CATH topology
3AB2A 3EK6A 3S6HA 2OGXA 2J4KA 2X2WA 3B8GA 4JZ7A 3D2MA 4NDPA 2R8VA 2BNEA 3K4OA 2WXBA 3L76A 2JJXA 4NDRB 2BUFA 3S6KA 4NDOA 3QUOA 2R98A 4NDOB 2J0XA 2RD5A 2OGXB 4NDQB 4AB7A 3L86A 2J0WA 3EK5A 4I49A 3AAWA 1OHBA 4F6TB 3WWNA 4NDRA 2J5VA 2A1FA 2BNFA 2CDQA 2W21A 2BRIA 1Z9DA 3WWMA 1B7BA 2J4JA 3QURA 2BMUA 3T7BA 3C1NA 4JZ8A 1OH9A 2V4YA 3TVIA 2J5TA 2BTYA 1YBDA 2WE5A 4KZTA 3NWYA 3QVHA 4JZ9A 2J4LA 2VA1A 2JI5A 3D40A 2IJ9A 1GSJA 1OHAA 4A7XA 3QVFA 3ZZHA 4USJA 3LKKA 4F6TA 3ZZFA 2AKOA 3LL5A 3QUNA 3LL9A 2HMFA 3K56A 3ZZGA 4Q1TA 2WE4A 3U6UA 3D2PA 2AP9A 2E9YA 3C20A 3C1MA 3S6GA 3KZFA 3D41A 4NDQA 2BNDA 4NDPB 2BRXA 4OLCA 3AB4A 4AXSA 3K52A 1GS5A 3K4YA 4A7WA 2V5HA 2JJ4A 3ZZIA 1E19A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AB2 A;  3EK6 A;  3S6H A;  2OGX A;  2J4K A;  2X2W A;  3B8G A;  4JZ7 A;  3D2M A;  4NDP A;  2R8V A;  2BNE A;  3K4O A;  2WXB A;  3L76 A;  2JJX A;  4NDR B;  2BUF A;  3S6K A;  4NDO A;  3QUO A;  2R98 A;  4NDO B;  2J0X A;  2RD5 A;  2OGX B;  4NDQ B;  4AB7 A;  3L86 A;  2J0W A;  3EK5 A;  4I49 A;  3AAW A;  1OHB A;  4F6T B;  3WWN A;  4NDR A;  2J5V A;  2A1F A;  2BNF A;  2CDQ A;  2W21 A;  2BRI A;  1Z9D A;  3WWM A;  1B7B A;  2J4J A;  3QUR A;  2BMU A;  3T7B A;  3C1N A;  4JZ8 A;  1OH9 A;  2V4Y A;  3TVI A;  2J5T A;  2BTY A;  1YBD A;  2WE5 A;  4KZT A;  3NWY A;  3QVH A;  4JZ9 A;  2J4L A;  2VA1 A;  2JI5 A;  3D40 A;  2IJ9 A;  1GSJ A;  1OHA A;  4A7X A;  3QVF A;  3ZZH A;  4USJ A;  3LKK A;  4F6T A;  3ZZF A;  2AKO A;  3LL5 A;  3QUN A;  3LL9 A;  2HMF A;  3K56 A;  3ZZG A;  4Q1T A;  2WE4 A;  3U6U A;  3D2P A;  2AP9 A;  2E9Y A;  3C20 A;  3C1M A;  3S6G A;  3KZF A;  3D41 A;  4NDQ A;  2BND A;  4NDP B;  2BRX A;  4OLC A;  3AB4 A;  4AXS A;  3K52 A;  1GS5 A;  3K4Y A;  4A7W A;  2V5H A;  2JJ4 A;  3ZZI A;  1E19 A; 
#chains in the Genus database with same CATH topology
 3AB2 A;  3EK6 A;  3S6H A;  2OGX A;  2J4K A;  2X2W A;  3B8G A;  4JZ7 A;  3D2M A;  4NDP A;  2R8V A;  2BNE A;  3K4O A;  2WXB A;  3L76 A;  2JJX A;  4NDR B;  2BUF A;  3S6K A;  4NDO A;  3QUO A;  2R98 A;  4NDO B;  2J0X A;  2RD5 A;  2OGX B;  4NDQ B;  4AB7 A;  3L86 A;  2J0W A;  3EK5 A;  4I49 A;  3AAW A;  1OHB A;  4F6T B;  3WWN A;  4NDR A;  2J5V A;  2A1F A;  2BNF A;  2CDQ A;  2W21 A;  2BRI A;  1Z9D A;  3WWM A;  1B7B A;  2J4J A;  3QUR A;  2BMU A;  3T7B A;  3C1N A;  4JZ8 A;  1OH9 A;  2V4Y A;  3TVI A;  2J5T A;  2BTY A;  1YBD A;  2WE5 A;  4KZT A;  3NWY A;  3QVH A;  4JZ9 A;  2J4L A;  2VA1 A;  2JI5 A;  3D40 A;  2IJ9 A;  1GSJ A;  1OHA A;  4A7X A;  3QVF A;  3ZZH A;  4USJ A;  3LKK A;  4F6T A;  3ZZF A;  2AKO A;  3LL5 A;  3QUN A;  3LL9 A;  2HMF A;  3K56 A;  3ZZG A;  4Q1T A;  2WE4 A;  3U6U A;  3D2P A;  2AP9 A;  2E9Y A;  3C20 A;  3C1M A;  3S6G A;  3KZF A;  3D41 A;  4NDQ A;  2BND A;  4NDP B;  2BRX A;  4OLC A;  3AB4 A;  4AXS A;  3K52 A;  1GS5 A;  3K4Y A;  4A7W A;  2V5H A;  2JJ4 A;  3ZZI A;  1E19 A; 
#chains in the Genus database with same CATH homology
 3AB2 A;  3EK6 A;  3S6H A;  2OGX A;  2J4K A;  2X2W A;  3B8G A;  4JZ7 A;  3D2M A;  4NDP A;  2R8V A;  2BNE A;  3K4O A;  2WXB A;  3L76 A;  2JJX A;  4NDR B;  2BUF A;  3S6K A;  4NDO A;  3QUO A;  2R98 A;  4NDO B;  2J0X A;  2RD5 A;  2OGX B;  4NDQ B;  4AB7 A;  3L86 A;  2J0W A;  3EK5 A;  4I49 A;  3AAW A;  1OHB A;  4F6T B;  3WWN A;  4NDR A;  2J5V A;  2A1F A;  2BNF A;  2CDQ A;  2W21 A;  2BRI A;  1Z9D A;  3WWM A;  1B7B A;  2J4J A;  3QUR A;  2BMU A;  3T7B A;  3C1N A;  4JZ8 A;  1OH9 A;  2V4Y A;  3TVI A;  2J5T A;  2BTY A;  1YBD A;  2WE5 A;  4KZT A;  3NWY A;  3QVH A;  4JZ9 A;  2J4L A;  2VA1 A;  2JI5 A;  3D40 A;  2IJ9 A;  1GSJ A;  1OHA A;  4A7X A;  3QVF A;  3ZZH A;  4USJ A;  3LKK A;  4F6T A;  3ZZF A;  2AKO A;  3LL5 A;  3QUN A;  3LL9 A;  2HMF A;  3K56 A;  3ZZG A;  4Q1T A;  2WE4 A;  3U6U A;  3D2P A;  2AP9 A;  2E9Y A;  3C20 A;  3C1M A;  3S6G A;  3KZF A;  3D41 A;  4NDQ A;  2BND A;  4NDP B;  2BRX A;  4OLC A;  3AB4 A;  4AXS A;  3K52 A;  1GS5 A;  3K4Y A;  4A7W A;  2V5H A;  2JJ4 A;  3ZZI A;  1E19 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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