3QVHA

Crystal structure of fosfomycin resistance kinase foma from streptomyces wedmorensis complexed with adp
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
271
structure length
260
Chain Sequence
SGLVPRGSHMTPDFLAIKVGGSLFSRKDEPGSLDDDAVTRFARNFARLAETYRGRMVLISGGGAFGHGAIRHAFSLAGLTEATFEVKKRWAEKLRGIGVDAFPLQLAAMCTLRNGIPQLRSEVLRDVLDHGALPVLAGDALFDEHGKLWAFSSDRVPEVLLPMVEGRLRVVTLTDVDGIVTDGAGGDTILPEVDARSPEQAYAALWGSGAMHTKLDALVTCARRGAECFIMRGDPGSDLEFLTAPFSSWPAHVRSTRITT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA.
pubmed doi rcsb
molecule keywords FomA protein
source organism Streptomyces wedmorensis
molecule tags Transferase
total genus 79
structure length 260
sequence length 271
ec nomenclature
pdb deposition date 2011-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3qvhA00
4NDOA 2V5HA 3C1MA 4JZ7A 3K4OA 3ZZHA 1OH9A 2WE5A 2BNFA 4NDRA 2J4LA 3K4YA 2J5TA 2BTYA 4NDOB 3K56A 3ZZIA 4JZ9A 3ZZFA 3S6HA 3NWYA 2J5VA 1YBDA 2J0XA 1Z9DA 2BRIA 2JJXA 4NDRB 3WWNA 3LL5A 3QUNA 1OHBA 2BUFA 2CDQA 2AP9A 2J4KA 2BNDA 3T7BA 3EK5A 1E19A 2W21A 4KZTA 1GSJA 2A1FA 2BRXA 3S6GA 2R8VA 3C20A 2RD5A 4NDPA 3AB2A 2OGXA 1B7BA 2R98A 3B8GA 3K52A 3QURA 2WXBA 4AXSA 4USJA 3D2PA 4Q1TA 2J4JA 3QVFA 4NDPB 3LL9A 4F6TA 2OGXB 2VA1A 3ZZGA 4A7XA 3TVIA 1GS5A 2HMFA 3S6KA 2JI5A 1OHAA 2AKOA 4F6TB 2E9YA 2BNEA 3QVHA 4OLCA 2JJ4A 3QUOA 3D2MA 4A7WA 3C1NA 2X2WA 4I49A 4NDQA 4JZ8A 2V4YA 4AB7A 3L76A 3AB4A 3AAWA 3KZFA 2BMUA 2J0WA 2IJ9A 4NDQB 3U6UA 3EK6A 3D41A 3WWMA 3D40A 3LKKA 3L86A 2WE4A
chains in the Genus database with same CATH superfamily
4NDOA 2V5HA 3C1MA 4JZ7A 3K4OA 3ZZHA 1OH9A 2WE5A 2BNFA 4NDRA 2J4LA 3K4YA 2J5TA 2BTYA 4NDOB 3K56A 3ZZIA 4JZ9A 3ZZFA 3S6HA 3NWYA 2J5VA 1YBDA 2J0XA 1Z9DA 2BRIA 2JJXA 4NDRB 3WWNA 3LL5A 3QUNA 1OHBA 2BUFA 2CDQA 2AP9A 2J4KA 2BNDA 3T7BA 3EK5A 1E19A 2W21A 4KZTA 1GSJA 2A1FA 2BRXA 3S6GA 2R8VA 3C20A 2RD5A 4NDPA 3AB2A 2OGXA 1B7BA 2R98A 3B8GA 3K52A 3QURA 2WXBA 4AXSA 4USJA 3D2PA 4Q1TA 2J4JA 3QVFA 4NDPB 3LL9A 4F6TA 2OGXB 2VA1A 3ZZGA 4A7XA 3TVIA 1GS5A 2HMFA 3S6KA 2JI5A 1OHAA 2AKOA 4F6TB 2E9YA 2BNEA 3QVHA 4OLCA 2JJ4A 3QUOA 3D2MA 4A7WA 3C1NA 2X2WA 4I49A 4NDQA 4JZ8A 2V4YA 4AB7A 3L76A 3AB4A 3AAWA 3KZFA 2BMUA 2J0WA 2IJ9A 4NDQB 3U6UA 3EK6A 3D41A 3WWMA 3D40A 3LKKA 3L86A 2WE4A
chains in the Genus database with same CATH topology
4NDOA 2V5HA 3C1MA 4JZ7A 3K4OA 3ZZHA 1OH9A 2WE5A 2BNFA 4NDRA 2J4LA 3K4YA 2J5TA 2BTYA 4NDOB 3K56A 3ZZIA 4JZ9A 3ZZFA 3S6HA 3NWYA 2J5VA 1YBDA 2J0XA 1Z9DA 2BRIA 2JJXA 4NDRB 3WWNA 3LL5A 3QUNA 1OHBA 2BUFA 2CDQA 2AP9A 2J4KA 2BNDA 3T7BA 3EK5A 1E19A 2W21A 4KZTA 1GSJA 2A1FA 2BRXA 3S6GA 2R8VA 3C20A 2RD5A 4NDPA 3AB2A 2OGXA 1B7BA 2R98A 3B8GA 3K52A 3QURA 2WXBA 4AXSA 4USJA 3D2PA 4Q1TA 2J4JA 3QVFA 4NDPB 3LL9A 4F6TA 2OGXB 2VA1A 3ZZGA 4A7XA 3TVIA 1GS5A 2HMFA 3S6KA 2JI5A 1OHAA 2AKOA 4F6TB 2E9YA 2BNEA 3QVHA 4OLCA 2JJ4A 3QUOA 3D2MA 4A7WA 3C1NA 2X2WA 4I49A 4NDQA 4JZ8A 2V4YA 4AB7A 3L76A 3AB4A 3AAWA 3KZFA 2BMUA 2J0WA 2IJ9A 4NDQB 3U6UA 3EK6A 3D41A 3WWMA 3D40A 3LKKA 3L86A 2WE4A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4NDO A;  2V5H A;  3C1M A;  4JZ7 A;  3K4O A;  3ZZH A;  1OH9 A;  2WE5 A;  2BNF A;  4NDR A;  2J4L A;  3K4Y A;  2J5T A;  2BTY A;  4NDO B;  3K56 A;  3ZZI A;  4JZ9 A;  3ZZF A;  3S6H A;  3NWY A;  2J5V A;  1YBD A;  2J0X A;  1Z9D A;  2BRI A;  2JJX A;  4NDR B;  3WWN A;  3LL5 A;  3QUN A;  1OHB A;  2BUF A;  2CDQ A;  2AP9 A;  2J4K A;  2BND A;  3T7B A;  3EK5 A;  1E19 A;  2W21 A;  4KZT A;  1GSJ A;  2A1F A;  2BRX A;  3S6G A;  2R8V A;  3C20 A;  2RD5 A;  4NDP A;  3AB2 A;  2OGX A;  1B7B A;  2R98 A;  3B8G A;  3K52 A;  3QUR A;  2WXB A;  4AXS A;  4USJ A;  3D2P A;  4Q1T A;  2J4J A;  3QVF A;  4NDP B;  3LL9 A;  4F6T A;  2OGX B;  2VA1 A;  3ZZG A;  4A7X A;  3TVI A;  1GS5 A;  2HMF A;  3S6K A;  2JI5 A;  1OHA A;  2AKO A;  4F6T B;  2E9Y A;  2BNE A;  3QVH A;  4OLC A;  2JJ4 A;  3QUO A;  3D2M A;  4A7W A;  3C1N A;  2X2W A;  4I49 A;  4NDQ A;  4JZ8 A;  2V4Y A;  4AB7 A;  3L76 A;  3AB4 A;  3AAW A;  3KZF A;  2BMU A;  2J0W A;  2IJ9 A;  4NDQ B;  3U6U A;  3EK6 A;  3D41 A;  3WWM A;  3D40 A;  3LKK A;  3L86 A;  2WE4 A; 
#chains in the Genus database with same CATH topology
 4NDO A;  2V5H A;  3C1M A;  4JZ7 A;  3K4O A;  3ZZH A;  1OH9 A;  2WE5 A;  2BNF A;  4NDR A;  2J4L A;  3K4Y A;  2J5T A;  2BTY A;  4NDO B;  3K56 A;  3ZZI A;  4JZ9 A;  3ZZF A;  3S6H A;  3NWY A;  2J5V A;  1YBD A;  2J0X A;  1Z9D A;  2BRI A;  2JJX A;  4NDR B;  3WWN A;  3LL5 A;  3QUN A;  1OHB A;  2BUF A;  2CDQ A;  2AP9 A;  2J4K A;  2BND A;  3T7B A;  3EK5 A;  1E19 A;  2W21 A;  4KZT A;  1GSJ A;  2A1F A;  2BRX A;  3S6G A;  2R8V A;  3C20 A;  2RD5 A;  4NDP A;  3AB2 A;  2OGX A;  1B7B A;  2R98 A;  3B8G A;  3K52 A;  3QUR A;  2WXB A;  4AXS A;  4USJ A;  3D2P A;  4Q1T A;  2J4J A;  3QVF A;  4NDP B;  3LL9 A;  4F6T A;  2OGX B;  2VA1 A;  3ZZG A;  4A7X A;  3TVI A;  1GS5 A;  2HMF A;  3S6K A;  2JI5 A;  1OHA A;  2AKO A;  4F6T B;  2E9Y A;  2BNE A;  3QVH A;  4OLC A;  2JJ4 A;  3QUO A;  3D2M A;  4A7W A;  3C1N A;  2X2W A;  4I49 A;  4NDQ A;  4JZ8 A;  2V4Y A;  4AB7 A;  3L76 A;  3AB4 A;  3AAW A;  3KZF A;  2BMU A;  2J0W A;  2IJ9 A;  4NDQ B;  3U6U A;  3EK6 A;  3D41 A;  3WWM A;  3D40 A;  3LKK A;  3L86 A;  2WE4 A; 
#chains in the Genus database with same CATH homology
 4NDO A;  2V5H A;  3C1M A;  4JZ7 A;  3K4O A;  3ZZH A;  1OH9 A;  2WE5 A;  2BNF A;  4NDR A;  2J4L A;  3K4Y A;  2J5T A;  2BTY A;  4NDO B;  3K56 A;  3ZZI A;  4JZ9 A;  3ZZF A;  3S6H A;  3NWY A;  2J5V A;  1YBD A;  2J0X A;  1Z9D A;  2BRI A;  2JJX A;  4NDR B;  3WWN A;  3LL5 A;  3QUN A;  1OHB A;  2BUF A;  2CDQ A;  2AP9 A;  2J4K A;  2BND A;  3T7B A;  3EK5 A;  1E19 A;  2W21 A;  4KZT A;  1GSJ A;  2A1F A;  2BRX A;  3S6G A;  2R8V A;  3C20 A;  2RD5 A;  4NDP A;  3AB2 A;  2OGX A;  1B7B A;  2R98 A;  3B8G A;  3K52 A;  3QUR A;  2WXB A;  4AXS A;  4USJ A;  3D2P A;  4Q1T A;  2J4J A;  3QVF A;  4NDP B;  3LL9 A;  4F6T A;  2OGX B;  2VA1 A;  3ZZG A;  4A7X A;  3TVI A;  1GS5 A;  2HMF A;  3S6K A;  2JI5 A;  1OHA A;  2AKO A;  4F6T B;  2E9Y A;  2BNE A;  3QVH A;  4OLC A;  2JJ4 A;  3QUO A;  3D2M A;  4A7W A;  3C1N A;  2X2W A;  4I49 A;  4NDQ A;  4JZ8 A;  2V4Y A;  4AB7 A;  3L76 A;  3AB4 A;  3AAW A;  3KZF A;  2BMU A;  2J0W A;  2IJ9 A;  4NDQ B;  3U6U A;  3EK6 A;  3D41 A;  3WWM A;  3D40 A;  3LKK A;  3L86 A;  2WE4 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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