3QVHA

Crystal structure of fosfomycin resistance kinase foma from streptomyces wedmorensis complexed with adp
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
271
structure length
260
Chain Sequence
SGLVPRGSHMTPDFLAIKVGGSLFSRKDEPGSLDDDAVTRFARNFARLAETYRGRMVLISGGGAFGHGAIRHAFSLAGLTEATFEVKKRWAEKLRGIGVDAFPLQLAAMCTLRNGIPQLRSEVLRDVLDHGALPVLAGDALFDEHGKLWAFSSDRVPEVLLPMVEGRLRVVTLTDVDGIVTDGAGGDTILPEVDARSPEQAYAALWGSGAMHTKLDALVTCARRGAECFIMRGDPGSDLEFLTAPFSSWPAHVRSTRITT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA.
pubmed doi rcsb
molecule tags Transferase
source organism Streptomyces wedmorensis
molecule keywords FomA protein
total genus 79
structure length 260
sequence length 271
ec nomenclature
pdb deposition date 2011-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3qvhA00
3K52A 1B7BA 2JI5A 3EK5A 4A7WA 4AXSA 2V5HA 2J5TA 3D41A 4A7XA 3LL9A 3L86A 4NDRB 4NDRA 3C20A 3LKKA 3D2MA 2BRIA 3D2PA 3AB4A 3QURA 3S6HA 3K4YA 2VA1A 2E9YA 2HMFA 2CDQA 2BUFA 2V4YA 3ZZGA 4AB7A 2OGXB 3AB2A 2J4LA 3QUNA 2J0WA 3TVIA 2BNDA 2OGXA 3AAWA 3EK6A 3K4OA 3KZFA 2AKOA 1YBDA 2R98A 3S6KA 2JJXA 3T7BA 1OHBA 2J4JA 2WXBA 4JZ7A 4I49A 3WWMA 2W21A 2BRXA 2AP9A 2BNFA 3ZZIA 4KZTA 4Q1TA 3U6UA 4F6TB 2BNEA 3ZZFA 2BTYA 4NDOB 3WWNA 4F6TA 1OH9A 4NDOA 3B8GA 3QVHA 2IJ9A 2BMUA 2A1FA 2J4KA 3D40A 1GSJA 4NDQA 4JZ9A 3C1NA 3L76A 2WE4A 3QVFA 4JZ8A 3C1MA 2JJ4A 2RD5A 3S6GA 4NDPB 4USJA 1OHAA 2J0XA 4NDPA 2J5VA 1Z9DA 3QUOA 1E19A 4OLCA 2R8VA 3LL5A 3ZZHA 1GS5A 2X2WA 4NDQB 3NWYA 3K56A 2WE5A
chains in the Genus database with same CATH superfamily
3K52A 1B7BA 2JI5A 3EK5A 4A7WA 4AXSA 2V5HA 2J5TA 3D41A 4A7XA 3LL9A 3L86A 4NDRB 4NDRA 3C20A 3LKKA 3D2MA 2BRIA 3D2PA 3AB4A 3QURA 3S6HA 3K4YA 2VA1A 2E9YA 2HMFA 2CDQA 2BUFA 2V4YA 3ZZGA 4AB7A 2OGXB 3AB2A 2J4LA 3QUNA 2J0WA 3TVIA 2BNDA 2OGXA 3AAWA 3EK6A 3K4OA 3KZFA 2AKOA 1YBDA 2R98A 3S6KA 2JJXA 3T7BA 1OHBA 2J4JA 2WXBA 4JZ7A 4I49A 3WWMA 2W21A 2BRXA 2AP9A 2BNFA 3ZZIA 4KZTA 4Q1TA 3U6UA 4F6TB 2BNEA 3ZZFA 2BTYA 4NDOB 3WWNA 4F6TA 1OH9A 4NDOA 3B8GA 3QVHA 2IJ9A 2BMUA 2A1FA 2J4KA 3D40A 1GSJA 4NDQA 4JZ9A 3C1NA 3L76A 2WE4A 3QVFA 4JZ8A 3C1MA 2JJ4A 2RD5A 3S6GA 4NDPB 4USJA 1OHAA 2J0XA 4NDPA 2J5VA 1Z9DA 3QUOA 1E19A 4OLCA 2R8VA 3LL5A 3ZZHA 1GS5A 2X2WA 4NDQB 3NWYA 3K56A 2WE5A
chains in the Genus database with same CATH topology
3K52A 1B7BA 2JI5A 3EK5A 4A7WA 4AXSA 2V5HA 2J5TA 3D41A 4A7XA 3LL9A 3L86A 4NDRB 4NDRA 3C20A 3LKKA 3D2MA 2BRIA 3D2PA 3AB4A 3QURA 3S6HA 3K4YA 2VA1A 2E9YA 2HMFA 2CDQA 2BUFA 2V4YA 3ZZGA 4AB7A 2OGXB 3AB2A 2J4LA 3QUNA 2J0WA 3TVIA 2BNDA 2OGXA 3AAWA 3EK6A 3K4OA 3KZFA 2AKOA 1YBDA 2R98A 3S6KA 2JJXA 3T7BA 1OHBA 2J4JA 2WXBA 4JZ7A 4I49A 3WWMA 2W21A 2BRXA 2AP9A 2BNFA 3ZZIA 4KZTA 4Q1TA 3U6UA 4F6TB 2BNEA 3ZZFA 2BTYA 4NDOB 3WWNA 4F6TA 1OH9A 4NDOA 3B8GA 3QVHA 2IJ9A 2BMUA 2A1FA 2J4KA 3D40A 1GSJA 4NDQA 4JZ9A 3C1NA 3L76A 2WE4A 3QVFA 4JZ8A 3C1MA 2JJ4A 2RD5A 3S6GA 4NDPB 4USJA 1OHAA 2J0XA 4NDPA 2J5VA 1Z9DA 3QUOA 1E19A 4OLCA 2R8VA 3LL5A 3ZZHA 1GS5A 2X2WA 4NDQB 3NWYA 3K56A 2WE5A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3K52 A;  1B7B A;  2JI5 A;  3EK5 A;  4A7W A;  4AXS A;  2V5H A;  2J5T A;  3D41 A;  4A7X A;  3LL9 A;  3L86 A;  4NDR B;  4NDR A;  3C20 A;  3LKK A;  3D2M A;  2BRI A;  3D2P A;  3AB4 A;  3QUR A;  3S6H A;  3K4Y A;  2VA1 A;  2E9Y A;  2HMF A;  2CDQ A;  2BUF A;  2V4Y A;  3ZZG A;  4AB7 A;  2OGX B;  3AB2 A;  2J4L A;  3QUN A;  2J0W A;  3TVI A;  2BND A;  2OGX A;  3AAW A;  3EK6 A;  3K4O A;  3KZF A;  2AKO A;  1YBD A;  2R98 A;  3S6K A;  2JJX A;  3T7B A;  1OHB A;  2J4J A;  2WXB A;  4JZ7 A;  4I49 A;  3WWM A;  2W21 A;  2BRX A;  2AP9 A;  2BNF A;  3ZZI A;  4KZT A;  4Q1T A;  3U6U A;  4F6T B;  2BNE A;  3ZZF A;  2BTY A;  4NDO B;  3WWN A;  4F6T A;  1OH9 A;  4NDO A;  3B8G A;  3QVH A;  2IJ9 A;  2BMU A;  2A1F A;  2J4K A;  3D40 A;  1GSJ A;  4NDQ A;  4JZ9 A;  3C1N A;  3L76 A;  2WE4 A;  3QVF A;  4JZ8 A;  3C1M A;  2JJ4 A;  2RD5 A;  3S6G A;  4NDP B;  4USJ A;  1OHA A;  2J0X A;  4NDP A;  2J5V A;  1Z9D A;  3QUO A;  1E19 A;  4OLC A;  2R8V A;  3LL5 A;  3ZZH A;  1GS5 A;  2X2W A;  4NDQ B;  3NWY A;  3K56 A;  2WE5 A; 
#chains in the Genus database with same CATH topology
 3K52 A;  1B7B A;  2JI5 A;  3EK5 A;  4A7W A;  4AXS A;  2V5H A;  2J5T A;  3D41 A;  4A7X A;  3LL9 A;  3L86 A;  4NDR B;  4NDR A;  3C20 A;  3LKK A;  3D2M A;  2BRI A;  3D2P A;  3AB4 A;  3QUR A;  3S6H A;  3K4Y A;  2VA1 A;  2E9Y A;  2HMF A;  2CDQ A;  2BUF A;  2V4Y A;  3ZZG A;  4AB7 A;  2OGX B;  3AB2 A;  2J4L A;  3QUN A;  2J0W A;  3TVI A;  2BND A;  2OGX A;  3AAW A;  3EK6 A;  3K4O A;  3KZF A;  2AKO A;  1YBD A;  2R98 A;  3S6K A;  2JJX A;  3T7B A;  1OHB A;  2J4J A;  2WXB A;  4JZ7 A;  4I49 A;  3WWM A;  2W21 A;  2BRX A;  2AP9 A;  2BNF A;  3ZZI A;  4KZT A;  4Q1T A;  3U6U A;  4F6T B;  2BNE A;  3ZZF A;  2BTY A;  4NDO B;  3WWN A;  4F6T A;  1OH9 A;  4NDO A;  3B8G A;  3QVH A;  2IJ9 A;  2BMU A;  2A1F A;  2J4K A;  3D40 A;  1GSJ A;  4NDQ A;  4JZ9 A;  3C1N A;  3L76 A;  2WE4 A;  3QVF A;  4JZ8 A;  3C1M A;  2JJ4 A;  2RD5 A;  3S6G A;  4NDP B;  4USJ A;  1OHA A;  2J0X A;  4NDP A;  2J5V A;  1Z9D A;  3QUO A;  1E19 A;  4OLC A;  2R8V A;  3LL5 A;  3ZZH A;  1GS5 A;  2X2W A;  4NDQ B;  3NWY A;  3K56 A;  2WE5 A; 
#chains in the Genus database with same CATH homology
 3K52 A;  1B7B A;  2JI5 A;  3EK5 A;  4A7W A;  4AXS A;  2V5H A;  2J5T A;  3D41 A;  4A7X A;  3LL9 A;  3L86 A;  4NDR B;  4NDR A;  3C20 A;  3LKK A;  3D2M A;  2BRI A;  3D2P A;  3AB4 A;  3QUR A;  3S6H A;  3K4Y A;  2VA1 A;  2E9Y A;  2HMF A;  2CDQ A;  2BUF A;  2V4Y A;  3ZZG A;  4AB7 A;  2OGX B;  3AB2 A;  2J4L A;  3QUN A;  2J0W A;  3TVI A;  2BND A;  2OGX A;  3AAW A;  3EK6 A;  3K4O A;  3KZF A;  2AKO A;  1YBD A;  2R98 A;  3S6K A;  2JJX A;  3T7B A;  1OHB A;  2J4J A;  2WXB A;  4JZ7 A;  4I49 A;  3WWM A;  2W21 A;  2BRX A;  2AP9 A;  2BNF A;  3ZZI A;  4KZT A;  4Q1T A;  3U6U A;  4F6T B;  2BNE A;  3ZZF A;  2BTY A;  4NDO B;  3WWN A;  4F6T A;  1OH9 A;  4NDO A;  3B8G A;  3QVH A;  2IJ9 A;  2BMU A;  2A1F A;  2J4K A;  3D40 A;  1GSJ A;  4NDQ A;  4JZ9 A;  3C1N A;  3L76 A;  2WE4 A;  3QVF A;  4JZ8 A;  3C1M A;  2JJ4 A;  2RD5 A;  3S6G A;  4NDP B;  4USJ A;  1OHA A;  2J0X A;  4NDP A;  2J5V A;  1Z9D A;  3QUO A;  1E19 A;  4OLC A;  2R8V A;  3LL5 A;  3ZZH A;  1GS5 A;  2X2W A;  4NDQ B;  3NWY A;  3K56 A;  2WE5 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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