3L76A

Crystal structure of aspartate kinase from synechocystis
Total Genus 176
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
176
sequence length
599
structure length
585
Chain Sequence
ALIVQKFGGTSVGTVERIQAVAQRIKRTVQGGNSLVVVVSAMGKSTDVLVDLAQQISPNPCRREMDMLLSTGEQVSIALLSLALQEIDQPAISLTGAQVGIVTEILEIRPDRLEHHLREGKVVVVAGFQGIHLEITTLGRGGSDTSAVALAAALKADFCEIYTDVPGILTTDPRLVPEAQLMAEITCDEMLELASLGAKVLHPRAVEIARNYGIPLVVRSSWSDEPGTKVVAPPVQNRSLVGLEIAKAVDGVEYDADQAKVALLRVPDRPGVASKLFRDIAQQQVDIDLIIQSIHDGNSNDIAFTVVKDLLNTAEAVTSAIAPALRSYPEADQEAEIIVEKGIAKIAIAGAGMIGRPGIAAKMFKTLADVGVNIEMISTSEVKVSCVIDQRDADRAIAALSNAFGVTLSPPKNQTDLPAVRGVALDQDQAQIAIRHVPDRPGMAAQLFTALAEANISVDMIIQSQRCRINQGTPCRDIAFMVAEGDSSQAEAILQPLIKDWLDAAIVVNKAIAKVSIVGSGMIGHPGVAAHFFAALAQENINIEMIATSEIKISCVVPQDRGVDALKAAHSAFNLAGTKTVTVPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
molecule keywords Aspartokinase
publication title A new mode of dimerization of allosteric enzymes with ACT domains revealed by the crystal structure of the aspartate kinase from Cyanobacteria
pubmed doi rcsb
source organism Synechocystis
total genus 176
structure length 585
sequence length 599
chains with identical sequence B
ec nomenclature ec 2.7.2.4: Aspartate kinase.
pdb deposition date 2009-12-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01842 ACT ACT domain
A PF13840 ACT_7 ACT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3l76A01
3U6UA 4NDOA 4USJA 2X2WA 1GSJA 1OHAA 3EK6A 2IJ9A 2J5VA 2WE5A 3QUNA 3ZZIA 3NWYA 2BNEA 2BUFA 4F6TA 3AAWA 2JI5A 3T7BA 3TVIA 1B7BA 4OLCA 1E19A 2BRIA 2OGXB 2JJ4A 4NDOB 3S6KA 3ZZFA 2WE4A 3AB4A 3WWNA 3K4OA 2J0XA 2J0WA 2R98A 2J4LA 4I49A 3D41A 4NDQA 4NDRA 4AB7A 4F6TB 4A7WA 3C1NA 3LL9A 3D2MA 2BNFA 2V5HA 3WWMA 2J4KA 2BNDA 2CDQA 3S6GA 1Z9DA 3L76A 3QVHA 1YBDA 3AB2A 3C20A 3LKKA 3K4YA 2W21A 4NDQB 4NDRB 3L86A 3LL5A 4A7XA 4KZTA 4NDPA 2BMUA 4AXSA 1GS5A 3KZFA 3ZZHA 3B8GA 2AKOA 2J5TA 3K56A 2J4JA 3C1MA 1OH9A 2HMFA 3D40A 3QUOA 3S6HA 3K52A 4NDPB 3ZZGA 2VA1A 2WXBA 4JZ8A 4Q1TA 2BRXA 2R8VA 4JZ7A 2RD5A 2V4YA 4JZ9A 3EK5A 2AP9A 3QVFA 1OHBA 2E9YA 2BTYA 3D2PA 2A1FA 3QURA 2JJXA 2OGXA
chains in the Genus database with same CATH superfamily
3U6UA 4NDOA 4USJA 2X2WA 1GSJA 1OHAA 3EK6A 2IJ9A 2J5VA 2WE5A 3QUNA 3ZZIA 3NWYA 2BNEA 2BUFA 4F6TA 3AAWA 2JI5A 3T7BA 3TVIA 1B7BA 4OLCA 1E19A 2BRIA 2OGXB 2JJ4A 4NDOB 3S6KA 3ZZFA 2WE4A 3AB4A 3WWNA 3K4OA 2J0XA 2J0WA 2R98A 2J4LA 4I49A 3D41A 4NDQA 4NDRA 4AB7A 4F6TB 4A7WA 3C1NA 3LL9A 3D2MA 2BNFA 2V5HA 3WWMA 2J4KA 2BNDA 2CDQA 3S6GA 1Z9DA 3L76A 3QVHA 1YBDA 3AB2A 3C20A 3LKKA 3K4YA 2W21A 4NDQB 4NDRB 3L86A 3LL5A 4A7XA 4KZTA 4NDPA 2BMUA 4AXSA 1GS5A 3KZFA 3ZZHA 3B8GA 2AKOA 2J5TA 3K56A 2J4JA 3C1MA 1OH9A 2HMFA 3D40A 3QUOA 3S6HA 3K52A 4NDPB 3ZZGA 2VA1A 2WXBA 4JZ8A 4Q1TA 2BRXA 2R8VA 4JZ7A 2RD5A 2V4YA 4JZ9A 3EK5A 2AP9A 3QVFA 1OHBA 2E9YA 2BTYA 3D2PA 2A1FA 3QURA 2JJXA 2OGXA
chains in the Genus database with same CATH topology
3U6UA 4NDOA 4USJA 2X2WA 1GSJA 1OHAA 3EK6A 2IJ9A 2J5VA 2WE5A 3QUNA 3ZZIA 3NWYA 2BNEA 2BUFA 4F6TA 3AAWA 2JI5A 3T7BA 3TVIA 1B7BA 4OLCA 1E19A 2BRIA 2OGXB 2JJ4A 4NDOB 3S6KA 3ZZFA 2WE4A 3AB4A 3WWNA 3K4OA 2J0XA 2J0WA 2R98A 2J4LA 4I49A 3D41A 4NDQA 4NDRA 4AB7A 4F6TB 4A7WA 3C1NA 3LL9A 3D2MA 2BNFA 2V5HA 3WWMA 2J4KA 2BNDA 2CDQA 3S6GA 1Z9DA 3L76A 3QVHA 1YBDA 3AB2A 3C20A 3LKKA 3K4YA 2W21A 4NDQB 4NDRB 3L86A 3LL5A 4A7XA 4KZTA 4NDPA 2BMUA 4AXSA 1GS5A 3KZFA 3ZZHA 3B8GA 2AKOA 2J5TA 3K56A 2J4JA 3C1MA 1OH9A 2HMFA 3D40A 3QUOA 3S6HA 3K52A 4NDPB 3ZZGA 2VA1A 2WXBA 4JZ8A 4Q1TA 2BRXA 2R8VA 4JZ7A 2RD5A 2V4YA 4JZ9A 3EK5A 2AP9A 3QVFA 1OHBA 2E9YA 2BTYA 3D2PA 2A1FA 3QURA 2JJXA 2OGXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3U6U A;  4NDO A;  4USJ A;  2X2W A;  1GSJ A;  1OHA A;  3EK6 A;  2IJ9 A;  2J5V A;  2WE5 A;  3QUN A;  3ZZI A;  3NWY A;  2BNE A;  2BUF A;  4F6T A;  3AAW A;  2JI5 A;  3T7B A;  3TVI A;  1B7B A;  4OLC A;  1E19 A;  2BRI A;  2OGX B;  2JJ4 A;  4NDO B;  3S6K A;  3ZZF A;  2WE4 A;  3AB4 A;  3WWN A;  3K4O A;  2J0X A;  2J0W A;  2R98 A;  2J4L A;  4I49 A;  3D41 A;  4NDQ A;  4NDR A;  4AB7 A;  4F6T B;  4A7W A;  3C1N A;  3LL9 A;  3D2M A;  2BNF A;  2V5H A;  3WWM A;  2J4K A;  2BND A;  2CDQ A;  3S6G A;  1Z9D A;  3L76 A;  3QVH A;  1YBD A;  3AB2 A;  3C20 A;  3LKK A;  3K4Y A;  2W21 A;  4NDQ B;  4NDR B;  3L86 A;  3LL5 A;  4A7X A;  4KZT A;  4NDP A;  2BMU A;  4AXS A;  1GS5 A;  3KZF A;  3ZZH A;  3B8G A;  2AKO A;  2J5T A;  3K56 A;  2J4J A;  3C1M A;  1OH9 A;  2HMF A;  3D40 A;  3QUO A;  3S6H A;  3K52 A;  4NDP B;  3ZZG A;  2VA1 A;  2WXB A;  4JZ8 A;  4Q1T A;  2BRX A;  2R8V A;  4JZ7 A;  2RD5 A;  2V4Y A;  4JZ9 A;  3EK5 A;  2AP9 A;  3QVF A;  1OHB A;  2E9Y A;  2BTY A;  3D2P A;  2A1F A;  3QUR A;  2JJX A;  2OGX A; 
#chains in the Genus database with same CATH topology
 3U6U A;  4NDO A;  4USJ A;  2X2W A;  1GSJ A;  1OHA A;  3EK6 A;  2IJ9 A;  2J5V A;  2WE5 A;  3QUN A;  3ZZI A;  3NWY A;  2BNE A;  2BUF A;  4F6T A;  3AAW A;  2JI5 A;  3T7B A;  3TVI A;  1B7B A;  4OLC A;  1E19 A;  2BRI A;  2OGX B;  2JJ4 A;  4NDO B;  3S6K A;  3ZZF A;  2WE4 A;  3AB4 A;  3WWN A;  3K4O A;  2J0X A;  2J0W A;  2R98 A;  2J4L A;  4I49 A;  3D41 A;  4NDQ A;  4NDR A;  4AB7 A;  4F6T B;  4A7W A;  3C1N A;  3LL9 A;  3D2M A;  2BNF A;  2V5H A;  3WWM A;  2J4K A;  2BND A;  2CDQ A;  3S6G A;  1Z9D A;  3L76 A;  3QVH A;  1YBD A;  3AB2 A;  3C20 A;  3LKK A;  3K4Y A;  2W21 A;  4NDQ B;  4NDR B;  3L86 A;  3LL5 A;  4A7X A;  4KZT A;  4NDP A;  2BMU A;  4AXS A;  1GS5 A;  3KZF A;  3ZZH A;  3B8G A;  2AKO A;  2J5T A;  3K56 A;  2J4J A;  3C1M A;  1OH9 A;  2HMF A;  3D40 A;  3QUO A;  3S6H A;  3K52 A;  4NDP B;  3ZZG A;  2VA1 A;  2WXB A;  4JZ8 A;  4Q1T A;  2BRX A;  2R8V A;  4JZ7 A;  2RD5 A;  2V4Y A;  4JZ9 A;  3EK5 A;  2AP9 A;  3QVF A;  1OHB A;  2E9Y A;  2BTY A;  3D2P A;  2A1F A;  3QUR A;  2JJX A;  2OGX A; 
#chains in the Genus database with same CATH homology
 3U6U A;  4NDO A;  4USJ A;  2X2W A;  1GSJ A;  1OHA A;  3EK6 A;  2IJ9 A;  2J5V A;  2WE5 A;  3QUN A;  3ZZI A;  3NWY A;  2BNE A;  2BUF A;  4F6T A;  3AAW A;  2JI5 A;  3T7B A;  3TVI A;  1B7B A;  4OLC A;  1E19 A;  2BRI A;  2OGX B;  2JJ4 A;  4NDO B;  3S6K A;  3ZZF A;  2WE4 A;  3AB4 A;  3WWN A;  3K4O A;  2J0X A;  2J0W A;  2R98 A;  2J4L A;  4I49 A;  3D41 A;  4NDQ A;  4NDR A;  4AB7 A;  4F6T B;  4A7W A;  3C1N A;  3LL9 A;  3D2M A;  2BNF A;  2V5H A;  3WWM A;  2J4K A;  2BND A;  2CDQ A;  3S6G A;  1Z9D A;  3L76 A;  3QVH A;  1YBD A;  3AB2 A;  3C20 A;  3LKK A;  3K4Y A;  2W21 A;  4NDQ B;  4NDR B;  3L86 A;  3LL5 A;  4A7X A;  4KZT A;  4NDP A;  2BMU A;  4AXS A;  1GS5 A;  3KZF A;  3ZZH A;  3B8G A;  2AKO A;  2J5T A;  3K56 A;  2J4J A;  3C1M A;  1OH9 A;  2HMF A;  3D40 A;  3QUO A;  3S6H A;  3K52 A;  4NDP B;  3ZZG A;  2VA1 A;  2WXB A;  4JZ8 A;  4Q1T A;  2BRX A;  2R8V A;  4JZ7 A;  2RD5 A;  2V4Y A;  4JZ9 A;  3EK5 A;  2AP9 A;  3QVF A;  1OHB A;  2E9Y A;  2BTY A;  3D2P A;  2A1F A;  3QUR A;  2JJX A;  2OGX A; 
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similar chains in the pdb database (?% sequence similarity)

 
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