3L76A

Crystal structure of aspartate kinase from synechocystis
Total Genus 176
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
176
sequence length
599
structure length
585
Chain Sequence
ALIVQKFGGTSVGTVERIQAVAQRIKRTVQGGNSLVVVVSAMGKSTDVLVDLAQQISPNPCRREMDMLLSTGEQVSIALLSLALQEIDQPAISLTGAQVGIVTEILEIRPDRLEHHLREGKVVVVAGFQGIHLEITTLGRGGSDTSAVALAAALKADFCEIYTDVPGILTTDPRLVPEAQLMAEITCDEMLELASLGAKVLHPRAVEIARNYGIPLVVRSSWSDEPGTKVVAPPVQNRSLVGLEIAKAVDGVEYDADQAKVALLRVPDRPGVASKLFRDIAQQQVDIDLIIQSIHDGNSNDIAFTVVKDLLNTAEAVTSAIAPALRSYPEADQEAEIIVEKGIAKIAIAGAGMIGRPGIAAKMFKTLADVGVNIEMISTSEVKVSCVIDQRDADRAIAALSNAFGVTLSPPKNQTDLPAVRGVALDQDQAQIAIRHVPDRPGMAAQLFTALAEANISVDMIIQSQRCRINQGTPCRDIAFMVAEGDSSQAEAILQPLIKDWLDAAIVVNKAIAKVSIVGSGMIGHPGVAAHFFAALAQENINIEMIATSEIKISCVVPQDRGVDALKAAHSAFNLAGTKTVTVPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Aspartokinase
publication title A new mode of dimerization of allosteric enzymes with ACT domains revealed by the crystal structure of the aspartate kinase from Cyanobacteria
pubmed doi rcsb
source organism Synechocystis
molecule tags Transferase
total genus 176
structure length 585
sequence length 599
chains with identical sequence B
ec nomenclature ec 2.7.2.4: Aspartate kinase.
pdb deposition date 2009-12-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01842 ACT ACT domain
A PF13840 ACT_7 ACT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3l76A01
4OLCA 1Z9DA 4NDOA 3EK6A 4NDQA 4JZ7A 2J0WA 3S6HA 4A7XA 4AB7A 2BMUA 4NDQB 3C20A 2AP9A 2V4YA 2BNEA 3NWYA 2BUFA 3L86A 3LKKA 2WE5A 3QVFA 3ZZFA 3AAWA 4NDPB 4A7WA 3QUNA 3QUOA 4NDRA 3B8GA 2BRIA 4Q1TA 4AXSA 3ZZGA 3C1NA 1E19A 1GSJA 3C1MA 4USJA 4NDOB 3EK5A 2RD5A 3WWNA 2AKOA 2J4KA 2JJ4A 4KZTA 3K56A 2VA1A 1YBDA 2WE4A 3D40A 4F6TA 2V5HA 2J4LA 2BNFA 4JZ9A 4NDRB 2WXBA 3QVHA 3LL9A 3T7BA 3S6GA 3ZZIA 3AB2A 3QURA 2R8VA 2OGXA 3D41A 2JJXA 2X2WA 2CDQA 1OH9A 2BTYA 4JZ8A 3WWMA 2J5TA 3K4YA 2J4JA 2BNDA 3ZZHA 2J5VA 3TVIA 3LL5A 1OHBA 3L76A 3U6UA 4F6TB 2J0XA 1OHAA 3KZFA 3S6KA 2W21A 4NDPA 3AB4A 4I49A 3D2MA 2IJ9A 3D2PA 2A1FA 1GS5A 1B7BA 3K52A 3K4OA 2E9YA 2HMFA 2R98A 2BRXA 2JI5A 2OGXB
chains in the Genus database with same CATH superfamily
4OLCA 1Z9DA 4NDOA 3EK6A 4NDQA 4JZ7A 2J0WA 3S6HA 4A7XA 4AB7A 2BMUA 4NDQB 3C20A 2AP9A 2V4YA 2BNEA 3NWYA 2BUFA 3L86A 3LKKA 2WE5A 3QVFA 3ZZFA 3AAWA 4NDPB 4A7WA 3QUNA 3QUOA 4NDRA 3B8GA 2BRIA 4Q1TA 4AXSA 3ZZGA 3C1NA 1E19A 1GSJA 3C1MA 4USJA 4NDOB 3EK5A 2RD5A 3WWNA 2AKOA 2J4KA 2JJ4A 4KZTA 3K56A 2VA1A 1YBDA 2WE4A 3D40A 4F6TA 2V5HA 2J4LA 2BNFA 4JZ9A 4NDRB 2WXBA 3QVHA 3LL9A 3T7BA 3S6GA 3ZZIA 3AB2A 3QURA 2R8VA 2OGXA 3D41A 2JJXA 2X2WA 2CDQA 1OH9A 2BTYA 4JZ8A 3WWMA 2J5TA 3K4YA 2J4JA 2BNDA 3ZZHA 2J5VA 3TVIA 3LL5A 1OHBA 3L76A 3U6UA 4F6TB 2J0XA 1OHAA 3KZFA 3S6KA 2W21A 4NDPA 3AB4A 4I49A 3D2MA 2IJ9A 3D2PA 2A1FA 1GS5A 1B7BA 3K52A 3K4OA 2E9YA 2HMFA 2R98A 2BRXA 2JI5A 2OGXB
chains in the Genus database with same CATH topology
4OLCA 1Z9DA 4NDOA 3EK6A 4NDQA 4JZ7A 2J0WA 3S6HA 4A7XA 4AB7A 2BMUA 4NDQB 3C20A 2AP9A 2V4YA 2BNEA 3NWYA 2BUFA 3L86A 3LKKA 2WE5A 3QVFA 3ZZFA 3AAWA 4NDPB 4A7WA 3QUNA 3QUOA 4NDRA 3B8GA 2BRIA 4Q1TA 4AXSA 3ZZGA 3C1NA 1E19A 1GSJA 3C1MA 4USJA 4NDOB 3EK5A 2RD5A 3WWNA 2AKOA 2J4KA 2JJ4A 4KZTA 3K56A 2VA1A 1YBDA 2WE4A 3D40A 4F6TA 2V5HA 2J4LA 2BNFA 4JZ9A 4NDRB 2WXBA 3QVHA 3LL9A 3T7BA 3S6GA 3ZZIA 3AB2A 3QURA 2R8VA 2OGXA 3D41A 2JJXA 2X2WA 2CDQA 1OH9A 2BTYA 4JZ8A 3WWMA 2J5TA 3K4YA 2J4JA 2BNDA 3ZZHA 2J5VA 3TVIA 3LL5A 1OHBA 3L76A 3U6UA 4F6TB 2J0XA 1OHAA 3KZFA 3S6KA 2W21A 4NDPA 3AB4A 4I49A 3D2MA 2IJ9A 3D2PA 2A1FA 1GS5A 1B7BA 3K52A 3K4OA 2E9YA 2HMFA 2R98A 2BRXA 2JI5A 2OGXB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OLC A;  1Z9D A;  4NDO A;  3EK6 A;  4NDQ A;  4JZ7 A;  2J0W A;  3S6H A;  4A7X A;  4AB7 A;  2BMU A;  4NDQ B;  3C20 A;  2AP9 A;  2V4Y A;  2BNE A;  3NWY A;  2BUF A;  3L86 A;  3LKK A;  2WE5 A;  3QVF A;  3ZZF A;  3AAW A;  4NDP B;  4A7W A;  3QUN A;  3QUO A;  4NDR A;  3B8G A;  2BRI A;  4Q1T A;  4AXS A;  3ZZG A;  3C1N A;  1E19 A;  1GSJ A;  3C1M A;  4USJ A;  4NDO B;  3EK5 A;  2RD5 A;  3WWN A;  2AKO A;  2J4K A;  2JJ4 A;  4KZT A;  3K56 A;  2VA1 A;  1YBD A;  2WE4 A;  3D40 A;  4F6T A;  2V5H A;  2J4L A;  2BNF A;  4JZ9 A;  4NDR B;  2WXB A;  3QVH A;  3LL9 A;  3T7B A;  3S6G A;  3ZZI A;  3AB2 A;  3QUR A;  2R8V A;  2OGX A;  3D41 A;  2JJX A;  2X2W A;  2CDQ A;  1OH9 A;  2BTY A;  4JZ8 A;  3WWM A;  2J5T A;  3K4Y A;  2J4J A;  2BND A;  3ZZH A;  2J5V A;  3TVI A;  3LL5 A;  1OHB A;  3L76 A;  3U6U A;  4F6T B;  2J0X A;  1OHA A;  3KZF A;  3S6K A;  2W21 A;  4NDP A;  3AB4 A;  4I49 A;  3D2M A;  2IJ9 A;  3D2P A;  2A1F A;  1GS5 A;  1B7B A;  3K52 A;  3K4O A;  2E9Y A;  2HMF A;  2R98 A;  2BRX A;  2JI5 A;  2OGX B; 
#chains in the Genus database with same CATH topology
 4OLC A;  1Z9D A;  4NDO A;  3EK6 A;  4NDQ A;  4JZ7 A;  2J0W A;  3S6H A;  4A7X A;  4AB7 A;  2BMU A;  4NDQ B;  3C20 A;  2AP9 A;  2V4Y A;  2BNE A;  3NWY A;  2BUF A;  3L86 A;  3LKK A;  2WE5 A;  3QVF A;  3ZZF A;  3AAW A;  4NDP B;  4A7W A;  3QUN A;  3QUO A;  4NDR A;  3B8G A;  2BRI A;  4Q1T A;  4AXS A;  3ZZG A;  3C1N A;  1E19 A;  1GSJ A;  3C1M A;  4USJ A;  4NDO B;  3EK5 A;  2RD5 A;  3WWN A;  2AKO A;  2J4K A;  2JJ4 A;  4KZT A;  3K56 A;  2VA1 A;  1YBD A;  2WE4 A;  3D40 A;  4F6T A;  2V5H A;  2J4L A;  2BNF A;  4JZ9 A;  4NDR B;  2WXB A;  3QVH A;  3LL9 A;  3T7B A;  3S6G A;  3ZZI A;  3AB2 A;  3QUR A;  2R8V A;  2OGX A;  3D41 A;  2JJX A;  2X2W A;  2CDQ A;  1OH9 A;  2BTY A;  4JZ8 A;  3WWM A;  2J5T A;  3K4Y A;  2J4J A;  2BND A;  3ZZH A;  2J5V A;  3TVI A;  3LL5 A;  1OHB A;  3L76 A;  3U6U A;  4F6T B;  2J0X A;  1OHA A;  3KZF A;  3S6K A;  2W21 A;  4NDP A;  3AB4 A;  4I49 A;  3D2M A;  2IJ9 A;  3D2P A;  2A1F A;  1GS5 A;  1B7B A;  3K52 A;  3K4O A;  2E9Y A;  2HMF A;  2R98 A;  2BRX A;  2JI5 A;  2OGX B; 
#chains in the Genus database with same CATH homology
 4OLC A;  1Z9D A;  4NDO A;  3EK6 A;  4NDQ A;  4JZ7 A;  2J0W A;  3S6H A;  4A7X A;  4AB7 A;  2BMU A;  4NDQ B;  3C20 A;  2AP9 A;  2V4Y A;  2BNE A;  3NWY A;  2BUF A;  3L86 A;  3LKK A;  2WE5 A;  3QVF A;  3ZZF A;  3AAW A;  4NDP B;  4A7W A;  3QUN A;  3QUO A;  4NDR A;  3B8G A;  2BRI A;  4Q1T A;  4AXS A;  3ZZG A;  3C1N A;  1E19 A;  1GSJ A;  3C1M A;  4USJ A;  4NDO B;  3EK5 A;  2RD5 A;  3WWN A;  2AKO A;  2J4K A;  2JJ4 A;  4KZT A;  3K56 A;  2VA1 A;  1YBD A;  2WE4 A;  3D40 A;  4F6T A;  2V5H A;  2J4L A;  2BNF A;  4JZ9 A;  4NDR B;  2WXB A;  3QVH A;  3LL9 A;  3T7B A;  3S6G A;  3ZZI A;  3AB2 A;  3QUR A;  2R8V A;  2OGX A;  3D41 A;  2JJX A;  2X2W A;  2CDQ A;  1OH9 A;  2BTY A;  4JZ8 A;  3WWM A;  2J5T A;  3K4Y A;  2J4J A;  2BND A;  3ZZH A;  2J5V A;  3TVI A;  3LL5 A;  1OHB A;  3L76 A;  3U6U A;  4F6T B;  2J0X A;  1OHA A;  3KZF A;  3S6K A;  2W21 A;  4NDP A;  3AB4 A;  4I49 A;  3D2M A;  2IJ9 A;  3D2P A;  2A1F A;  1GS5 A;  1B7B A;  3K52 A;  3K4O A;  2E9Y A;  2HMF A;  2R98 A;  2BRX A;  2JI5 A;  2OGX B; 
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similar chains in the pdb database (?% sequence similarity)

 
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