3L76A

Crystal structure of aspartate kinase from synechocystis
Total Genus 176
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
176
sequence length
599
structure length
585
Chain Sequence
ALIVQKFGGTSVGTVERIQAVAQRIKRTVQGGNSLVVVVSAMGKSTDVLVDLAQQISPNPCRREMDMLLSTGEQVSIALLSLALQEIDQPAISLTGAQVGIVTEILEIRPDRLEHHLREGKVVVVAGFQGIHLEITTLGRGGSDTSAVALAAALKADFCEIYTDVPGILTTDPRLVPEAQLMAEITCDEMLELASLGAKVLHPRAVEIARNYGIPLVVRSSWSDEPGTKVVAPPVQNRSLVGLEIAKAVDGVEYDADQAKVALLRVPDRPGVASKLFRDIAQQQVDIDLIIQSIHDGNSNDIAFTVVKDLLNTAEAVTSAIAPALRSYPEADQEAEIIVEKGIAKIAIAGAGMIGRPGIAAKMFKTLADVGVNIEMISTSEVKVSCVIDQRDADRAIAALSNAFGVTLSPPKNQTDLPAVRGVALDQDQAQIAIRHVPDRPGMAAQLFTALAEANISVDMIIQSQRCRINQGTPCRDIAFMVAEGDSSQAEAILQPLIKDWLDAAIVVNKAIAKVSIVGSGMIGHPGVAAHFFAALAQENINIEMIATSEIKISCVVPQDRGVDALKAAHSAFNLAGTKTVTVPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
molecule tags Transferase
molecule keywords Aspartokinase
publication title A new mode of dimerization of allosteric enzymes with ACT domains revealed by the crystal structure of the aspartate kinase from Cyanobacteria
pubmed doi rcsb
source organism Synechocystis
total genus 176
structure length 585
sequence length 599
chains with identical sequence B
ec nomenclature ec 2.7.2.4: Aspartate kinase.
pdb deposition date 2009-12-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01842 ACT ACT domain
A PF13840 ACT_7 ACT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3l76A01
3D40A 4JZ8A 2J5VA 3QURA 3WWMA 2J4JA 2BNFA 3K52A 3D2MA 4JZ9A 3NWYA 2BMUA 2R98A 2X2WA 3TVIA 2V5HA 3QUOA 2J5TA 3S6KA 2RD5A 3ZZFA 2CDQA 4JZ7A 3EK6A 4NDQB 1Z9DA 2J4KA 4Q1TA 4NDQA 2BNEA 1YBDA 2WE4A 2R8VA 2J4LA 1GS5A 4F6TB 3D2PA 1OH9A 3AB2A 4F6TA 2AKOA 2JJ4A 3QVHA 3C1MA 4AB7A 2A1FA 3L86A 2J0XA 2E9YA 1OHBA 2BRIA 3T7BA 3ZZGA 3ZZHA 1E19A 4OLCA 3S6GA 3K4OA 2WXBA 2BNDA 2AP9A 2J0WA 4I49A 3ZZIA 2JI5A 3U6UA 3WWNA 2BUFA 3LL5A 3C20A 3EK5A 4USJA 3QVFA 3K4YA 3C1NA 4NDOB 3L76A 3LL9A 3LKKA 4NDOA 2BTYA 2WE5A 3QUNA 2OGXB 3D41A 2BRXA 1B7BA 2OGXA 4KZTA 4A7WA 2JJXA 4NDPB 4A7XA 1GSJA 3K56A 4NDPA 2W21A 4AXSA 3S6HA 2V4YA 3AAWA 4NDRB 2IJ9A 2HMFA 1OHAA 4NDRA 2VA1A 3B8GA 3KZFA 3AB4A
chains in the Genus database with same CATH superfamily
3D40A 4JZ8A 2J5VA 3QURA 3WWMA 2J4JA 2BNFA 3K52A 3D2MA 4JZ9A 3NWYA 2BMUA 2R98A 2X2WA 3TVIA 2V5HA 3QUOA 2J5TA 3S6KA 2RD5A 3ZZFA 2CDQA 4JZ7A 3EK6A 4NDQB 1Z9DA 2J4KA 4Q1TA 4NDQA 2BNEA 1YBDA 2WE4A 2R8VA 2J4LA 1GS5A 4F6TB 3D2PA 1OH9A 3AB2A 4F6TA 2AKOA 2JJ4A 3QVHA 3C1MA 4AB7A 2A1FA 3L86A 2J0XA 2E9YA 1OHBA 2BRIA 3T7BA 3ZZGA 3ZZHA 1E19A 4OLCA 3S6GA 3K4OA 2WXBA 2BNDA 2AP9A 2J0WA 4I49A 3ZZIA 2JI5A 3U6UA 3WWNA 2BUFA 3LL5A 3C20A 3EK5A 4USJA 3QVFA 3K4YA 3C1NA 4NDOB 3L76A 3LL9A 3LKKA 4NDOA 2BTYA 2WE5A 3QUNA 2OGXB 3D41A 2BRXA 1B7BA 2OGXA 4KZTA 4A7WA 2JJXA 4NDPB 4A7XA 1GSJA 3K56A 4NDPA 2W21A 4AXSA 3S6HA 2V4YA 3AAWA 4NDRB 2IJ9A 2HMFA 1OHAA 4NDRA 2VA1A 3B8GA 3KZFA 3AB4A
chains in the Genus database with same CATH topology
3D40A 4JZ8A 2J5VA 3QURA 3WWMA 2J4JA 2BNFA 3K52A 3D2MA 4JZ9A 3NWYA 2BMUA 2R98A 2X2WA 3TVIA 2V5HA 3QUOA 2J5TA 3S6KA 2RD5A 3ZZFA 2CDQA 4JZ7A 3EK6A 4NDQB 1Z9DA 2J4KA 4Q1TA 4NDQA 2BNEA 1YBDA 2WE4A 2R8VA 2J4LA 1GS5A 4F6TB 3D2PA 1OH9A 3AB2A 4F6TA 2AKOA 2JJ4A 3QVHA 3C1MA 4AB7A 2A1FA 3L86A 2J0XA 2E9YA 1OHBA 2BRIA 3T7BA 3ZZGA 3ZZHA 1E19A 4OLCA 3S6GA 3K4OA 2WXBA 2BNDA 2AP9A 2J0WA 4I49A 3ZZIA 2JI5A 3U6UA 3WWNA 2BUFA 3LL5A 3C20A 3EK5A 4USJA 3QVFA 3K4YA 3C1NA 4NDOB 3L76A 3LL9A 3LKKA 4NDOA 2BTYA 2WE5A 3QUNA 2OGXB 3D41A 2BRXA 1B7BA 2OGXA 4KZTA 4A7WA 2JJXA 4NDPB 4A7XA 1GSJA 3K56A 4NDPA 2W21A 4AXSA 3S6HA 2V4YA 3AAWA 4NDRB 2IJ9A 2HMFA 1OHAA 4NDRA 2VA1A 3B8GA 3KZFA 3AB4A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3D40 A;  4JZ8 A;  2J5V A;  3QUR A;  3WWM A;  2J4J A;  2BNF A;  3K52 A;  3D2M A;  4JZ9 A;  3NWY A;  2BMU A;  2R98 A;  2X2W A;  3TVI A;  2V5H A;  3QUO A;  2J5T A;  3S6K A;  2RD5 A;  3ZZF A;  2CDQ A;  4JZ7 A;  3EK6 A;  4NDQ B;  1Z9D A;  2J4K A;  4Q1T A;  4NDQ A;  2BNE A;  1YBD A;  2WE4 A;  2R8V A;  2J4L A;  1GS5 A;  4F6T B;  3D2P A;  1OH9 A;  3AB2 A;  4F6T A;  2AKO A;  2JJ4 A;  3QVH A;  3C1M A;  4AB7 A;  2A1F A;  3L86 A;  2J0X A;  2E9Y A;  1OHB A;  2BRI A;  3T7B A;  3ZZG A;  3ZZH A;  1E19 A;  4OLC A;  3S6G A;  3K4O A;  2WXB A;  2BND A;  2AP9 A;  2J0W A;  4I49 A;  3ZZI A;  2JI5 A;  3U6U A;  3WWN A;  2BUF A;  3LL5 A;  3C20 A;  3EK5 A;  4USJ A;  3QVF A;  3K4Y A;  3C1N A;  4NDO B;  3L76 A;  3LL9 A;  3LKK A;  4NDO A;  2BTY A;  2WE5 A;  3QUN A;  2OGX B;  3D41 A;  2BRX A;  1B7B A;  2OGX A;  4KZT A;  4A7W A;  2JJX A;  4NDP B;  4A7X A;  1GSJ A;  3K56 A;  4NDP A;  2W21 A;  4AXS A;  3S6H A;  2V4Y A;  3AAW A;  4NDR B;  2IJ9 A;  2HMF A;  1OHA A;  4NDR A;  2VA1 A;  3B8G A;  3KZF A;  3AB4 A; 
#chains in the Genus database with same CATH topology
 3D40 A;  4JZ8 A;  2J5V A;  3QUR A;  3WWM A;  2J4J A;  2BNF A;  3K52 A;  3D2M A;  4JZ9 A;  3NWY A;  2BMU A;  2R98 A;  2X2W A;  3TVI A;  2V5H A;  3QUO A;  2J5T A;  3S6K A;  2RD5 A;  3ZZF A;  2CDQ A;  4JZ7 A;  3EK6 A;  4NDQ B;  1Z9D A;  2J4K A;  4Q1T A;  4NDQ A;  2BNE A;  1YBD A;  2WE4 A;  2R8V A;  2J4L A;  1GS5 A;  4F6T B;  3D2P A;  1OH9 A;  3AB2 A;  4F6T A;  2AKO A;  2JJ4 A;  3QVH A;  3C1M A;  4AB7 A;  2A1F A;  3L86 A;  2J0X A;  2E9Y A;  1OHB A;  2BRI A;  3T7B A;  3ZZG A;  3ZZH A;  1E19 A;  4OLC A;  3S6G A;  3K4O A;  2WXB A;  2BND A;  2AP9 A;  2J0W A;  4I49 A;  3ZZI A;  2JI5 A;  3U6U A;  3WWN A;  2BUF A;  3LL5 A;  3C20 A;  3EK5 A;  4USJ A;  3QVF A;  3K4Y A;  3C1N A;  4NDO B;  3L76 A;  3LL9 A;  3LKK A;  4NDO A;  2BTY A;  2WE5 A;  3QUN A;  2OGX B;  3D41 A;  2BRX A;  1B7B A;  2OGX A;  4KZT A;  4A7W A;  2JJX A;  4NDP B;  4A7X A;  1GSJ A;  3K56 A;  4NDP A;  2W21 A;  4AXS A;  3S6H A;  2V4Y A;  3AAW A;  4NDR B;  2IJ9 A;  2HMF A;  1OHA A;  4NDR A;  2VA1 A;  3B8G A;  3KZF A;  3AB4 A; 
#chains in the Genus database with same CATH homology
 3D40 A;  4JZ8 A;  2J5V A;  3QUR A;  3WWM A;  2J4J A;  2BNF A;  3K52 A;  3D2M A;  4JZ9 A;  3NWY A;  2BMU A;  2R98 A;  2X2W A;  3TVI A;  2V5H A;  3QUO A;  2J5T A;  3S6K A;  2RD5 A;  3ZZF A;  2CDQ A;  4JZ7 A;  3EK6 A;  4NDQ B;  1Z9D A;  2J4K A;  4Q1T A;  4NDQ A;  2BNE A;  1YBD A;  2WE4 A;  2R8V A;  2J4L A;  1GS5 A;  4F6T B;  3D2P A;  1OH9 A;  3AB2 A;  4F6T A;  2AKO A;  2JJ4 A;  3QVH A;  3C1M A;  4AB7 A;  2A1F A;  3L86 A;  2J0X A;  2E9Y A;  1OHB A;  2BRI A;  3T7B A;  3ZZG A;  3ZZH A;  1E19 A;  4OLC A;  3S6G A;  3K4O A;  2WXB A;  2BND A;  2AP9 A;  2J0W A;  4I49 A;  3ZZI A;  2JI5 A;  3U6U A;  3WWN A;  2BUF A;  3LL5 A;  3C20 A;  3EK5 A;  4USJ A;  3QVF A;  3K4Y A;  3C1N A;  4NDO B;  3L76 A;  3LL9 A;  3LKK A;  4NDO A;  2BTY A;  2WE5 A;  3QUN A;  2OGX B;  3D41 A;  2BRX A;  1B7B A;  2OGX A;  4KZT A;  4A7W A;  2JJX A;  4NDP B;  4A7X A;  1GSJ A;  3K56 A;  4NDP A;  2W21 A;  4AXS A;  3S6H A;  2V4Y A;  3AAW A;  4NDR B;  2IJ9 A;  2HMF A;  1OHA A;  4NDR A;  2VA1 A;  3B8G A;  3KZF A;  3AB4 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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