3L76A

Crystal structure of aspartate kinase from synechocystis
Total Genus 176
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
176
sequence length
599
structure length
585
Chain Sequence
ALIVQKFGGTSVGTVERIQAVAQRIKRTVQGGNSLVVVVSAMGKSTDVLVDLAQQISPNPCRREMDMLLSTGEQVSIALLSLALQEIDQPAISLTGAQVGIVTEILEIRPDRLEHHLREGKVVVVAGFQGIHLEITTLGRGGSDTSAVALAAALKADFCEIYTDVPGILTTDPRLVPEAQLMAEITCDEMLELASLGAKVLHPRAVEIARNYGIPLVVRSSWSDEPGTKVVAPPVQNRSLVGLEIAKAVDGVEYDADQAKVALLRVPDRPGVASKLFRDIAQQQVDIDLIIQSIHDGNSNDIAFTVVKDLLNTAEAVTSAIAPALRSYPEADQEAEIIVEKGIAKIAIAGAGMIGRPGIAAKMFKTLADVGVNIEMISTSEVKVSCVIDQRDADRAIAALSNAFGVTLSPPKNQTDLPAVRGVALDQDQAQIAIRHVPDRPGMAAQLFTALAEANISVDMIIQSQRCRINQGTPCRDIAFMVAEGDSSQAEAILQPLIKDWLDAAIVVNKAIAKVSIVGSGMIGHPGVAAHFFAALAQENINIEMIATSEIKISCVVPQDRGVDALKAAHSAFNLAGTKTVTVPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
publication title A new mode of dimerization of allosteric enzymes with ACT domains revealed by the crystal structure of the aspartate kinase from Cyanobacteria
pubmed doi rcsb
molecule keywords Aspartokinase
molecule tags Transferase
source organism Synechocystis
total genus 176
structure length 585
sequence length 599
chains with identical sequence B
ec nomenclature ec 2.7.2.4: Aspartate kinase.
pdb deposition date 2009-12-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01842 ACT ACT domain
A PF13840 ACT_7 ACT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3l76A01
4OLCA 3U6UA 3QUOA 3S6KA 3D2MA 3C1NA 2J4LA 3C1MA 1GS5A 3S6GA 1YBDA 4KZTA 3K56A 3ZZIA 3K52A 4Q1TA 3K4OA 2JJ4A 2A1FA 2OGXA 4JZ8A 4NDRA 3D41A 4NDRB 2JI5A 4F6TA 2BTYA 3KZFA 4A7WA 4F6TB 1OH9A 3C20A 3L76A 2RD5A 1OHBA 3L86A 2R8VA 3D40A 3QUNA 4NDQA 2JJXA 2HMFA 4NDQB 3B8GA 3S6HA 4AXSA 2J4KA 2J4JA 2IJ9A 3ZZFA 2V5HA 2BUFA 3ZZHA 3EK6A 1OHAA 1B7BA 3QURA 2J5VA 2J0XA 2WXBA 3LL9A 4AB7A 2J5TA 4USJA 1GSJA 3D2PA 4JZ9A 3ZZGA 2AP9A 2BNFA 3WWNA 2BRXA 4NDOA 2BRIA 2BNEA 4A7XA 4NDOB 3QVFA 2WE5A 3LKKA 3AAWA 1E19A 2R98A 4NDPA 2AKOA 4NDPB 2V4YA 2VA1A 3K4YA 4JZ7A 2CDQA 3EK5A 2J0WA 2E9YA 3AB4A 4I49A 3WWMA 2WE4A 3T7BA 3TVIA 2W21A 3NWYA 1Z9DA 3AB2A 2BMUA 2BNDA 3LL5A 2X2WA 3QVHA 2OGXB
chains in the Genus database with same CATH superfamily
4OLCA 3U6UA 3QUOA 3S6KA 3D2MA 3C1NA 2J4LA 3C1MA 1GS5A 3S6GA 1YBDA 4KZTA 3K56A 3ZZIA 3K52A 4Q1TA 3K4OA 2JJ4A 2A1FA 2OGXA 4JZ8A 4NDRA 3D41A 4NDRB 2JI5A 4F6TA 2BTYA 3KZFA 4A7WA 4F6TB 1OH9A 3C20A 3L76A 2RD5A 1OHBA 3L86A 2R8VA 3D40A 3QUNA 4NDQA 2JJXA 2HMFA 4NDQB 3B8GA 3S6HA 4AXSA 2J4KA 2J4JA 2IJ9A 3ZZFA 2V5HA 2BUFA 3ZZHA 3EK6A 1OHAA 1B7BA 3QURA 2J5VA 2J0XA 2WXBA 3LL9A 4AB7A 2J5TA 4USJA 1GSJA 3D2PA 4JZ9A 3ZZGA 2AP9A 2BNFA 3WWNA 2BRXA 4NDOA 2BRIA 2BNEA 4A7XA 4NDOB 3QVFA 2WE5A 3LKKA 3AAWA 1E19A 2R98A 4NDPA 2AKOA 4NDPB 2V4YA 2VA1A 3K4YA 4JZ7A 2CDQA 3EK5A 2J0WA 2E9YA 3AB4A 4I49A 3WWMA 2WE4A 3T7BA 3TVIA 2W21A 3NWYA 1Z9DA 3AB2A 2BMUA 2BNDA 3LL5A 2X2WA 3QVHA 2OGXB
chains in the Genus database with same CATH topology
4OLCA 3U6UA 3QUOA 3S6KA 3D2MA 3C1NA 2J4LA 3C1MA 1GS5A 3S6GA 1YBDA 4KZTA 3K56A 3ZZIA 3K52A 4Q1TA 3K4OA 2JJ4A 2A1FA 2OGXA 4JZ8A 4NDRA 3D41A 4NDRB 2JI5A 4F6TA 2BTYA 3KZFA 4A7WA 4F6TB 1OH9A 3C20A 3L76A 2RD5A 1OHBA 3L86A 2R8VA 3D40A 3QUNA 4NDQA 2JJXA 2HMFA 4NDQB 3B8GA 3S6HA 4AXSA 2J4KA 2J4JA 2IJ9A 3ZZFA 2V5HA 2BUFA 3ZZHA 3EK6A 1OHAA 1B7BA 3QURA 2J5VA 2J0XA 2WXBA 3LL9A 4AB7A 2J5TA 4USJA 1GSJA 3D2PA 4JZ9A 3ZZGA 2AP9A 2BNFA 3WWNA 2BRXA 4NDOA 2BRIA 2BNEA 4A7XA 4NDOB 3QVFA 2WE5A 3LKKA 3AAWA 1E19A 2R98A 4NDPA 2AKOA 4NDPB 2V4YA 2VA1A 3K4YA 4JZ7A 2CDQA 3EK5A 2J0WA 2E9YA 3AB4A 4I49A 3WWMA 2WE4A 3T7BA 3TVIA 2W21A 3NWYA 1Z9DA 3AB2A 2BMUA 2BNDA 3LL5A 2X2WA 3QVHA 2OGXB
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4OLC A;  3U6U A;  3QUO A;  3S6K A;  3D2M A;  3C1N A;  2J4L A;  3C1M A;  1GS5 A;  3S6G A;  1YBD A;  4KZT A;  3K56 A;  3ZZI A;  3K52 A;  4Q1T A;  3K4O A;  2JJ4 A;  2A1F A;  2OGX A;  4JZ8 A;  4NDR A;  3D41 A;  4NDR B;  2JI5 A;  4F6T A;  2BTY A;  3KZF A;  4A7W A;  4F6T B;  1OH9 A;  3C20 A;  3L76 A;  2RD5 A;  1OHB A;  3L86 A;  2R8V A;  3D40 A;  3QUN A;  4NDQ A;  2JJX A;  2HMF A;  4NDQ B;  3B8G A;  3S6H A;  4AXS A;  2J4K A;  2J4J A;  2IJ9 A;  3ZZF A;  2V5H A;  2BUF A;  3ZZH A;  3EK6 A;  1OHA A;  1B7B A;  3QUR A;  2J5V A;  2J0X A;  2WXB A;  3LL9 A;  4AB7 A;  2J5T A;  4USJ A;  1GSJ A;  3D2P A;  4JZ9 A;  3ZZG A;  2AP9 A;  2BNF A;  3WWN A;  2BRX A;  4NDO A;  2BRI A;  2BNE A;  4A7X A;  4NDO B;  3QVF A;  2WE5 A;  3LKK A;  3AAW A;  1E19 A;  2R98 A;  4NDP A;  2AKO A;  4NDP B;  2V4Y A;  2VA1 A;  3K4Y A;  4JZ7 A;  2CDQ A;  3EK5 A;  2J0W A;  2E9Y A;  3AB4 A;  4I49 A;  3WWM A;  2WE4 A;  3T7B A;  3TVI A;  2W21 A;  3NWY A;  1Z9D A;  3AB2 A;  2BMU A;  2BND A;  3LL5 A;  2X2W A;  3QVH A;  2OGX B; 
#chains in the Genus database with same CATH topology
 4OLC A;  3U6U A;  3QUO A;  3S6K A;  3D2M A;  3C1N A;  2J4L A;  3C1M A;  1GS5 A;  3S6G A;  1YBD A;  4KZT A;  3K56 A;  3ZZI A;  3K52 A;  4Q1T A;  3K4O A;  2JJ4 A;  2A1F A;  2OGX A;  4JZ8 A;  4NDR A;  3D41 A;  4NDR B;  2JI5 A;  4F6T A;  2BTY A;  3KZF A;  4A7W A;  4F6T B;  1OH9 A;  3C20 A;  3L76 A;  2RD5 A;  1OHB A;  3L86 A;  2R8V A;  3D40 A;  3QUN A;  4NDQ A;  2JJX A;  2HMF A;  4NDQ B;  3B8G A;  3S6H A;  4AXS A;  2J4K A;  2J4J A;  2IJ9 A;  3ZZF A;  2V5H A;  2BUF A;  3ZZH A;  3EK6 A;  1OHA A;  1B7B A;  3QUR A;  2J5V A;  2J0X A;  2WXB A;  3LL9 A;  4AB7 A;  2J5T A;  4USJ A;  1GSJ A;  3D2P A;  4JZ9 A;  3ZZG A;  2AP9 A;  2BNF A;  3WWN A;  2BRX A;  4NDO A;  2BRI A;  2BNE A;  4A7X A;  4NDO B;  3QVF A;  2WE5 A;  3LKK A;  3AAW A;  1E19 A;  2R98 A;  4NDP A;  2AKO A;  4NDP B;  2V4Y A;  2VA1 A;  3K4Y A;  4JZ7 A;  2CDQ A;  3EK5 A;  2J0W A;  2E9Y A;  3AB4 A;  4I49 A;  3WWM A;  2WE4 A;  3T7B A;  3TVI A;  2W21 A;  3NWY A;  1Z9D A;  3AB2 A;  2BMU A;  2BND A;  3LL5 A;  2X2W A;  3QVH A;  2OGX B; 
#chains in the Genus database with same CATH homology
 4OLC A;  3U6U A;  3QUO A;  3S6K A;  3D2M A;  3C1N A;  2J4L A;  3C1M A;  1GS5 A;  3S6G A;  1YBD A;  4KZT A;  3K56 A;  3ZZI A;  3K52 A;  4Q1T A;  3K4O A;  2JJ4 A;  2A1F A;  2OGX A;  4JZ8 A;  4NDR A;  3D41 A;  4NDR B;  2JI5 A;  4F6T A;  2BTY A;  3KZF A;  4A7W A;  4F6T B;  1OH9 A;  3C20 A;  3L76 A;  2RD5 A;  1OHB A;  3L86 A;  2R8V A;  3D40 A;  3QUN A;  4NDQ A;  2JJX A;  2HMF A;  4NDQ B;  3B8G A;  3S6H A;  4AXS A;  2J4K A;  2J4J A;  2IJ9 A;  3ZZF A;  2V5H A;  2BUF A;  3ZZH A;  3EK6 A;  1OHA A;  1B7B A;  3QUR A;  2J5V A;  2J0X A;  2WXB A;  3LL9 A;  4AB7 A;  2J5T A;  4USJ A;  1GSJ A;  3D2P A;  4JZ9 A;  3ZZG A;  2AP9 A;  2BNF A;  3WWN A;  2BRX A;  4NDO A;  2BRI A;  2BNE A;  4A7X A;  4NDO B;  3QVF A;  2WE5 A;  3LKK A;  3AAW A;  1E19 A;  2R98 A;  4NDP A;  2AKO A;  4NDP B;  2V4Y A;  2VA1 A;  3K4Y A;  4JZ7 A;  2CDQ A;  3EK5 A;  2J0W A;  2E9Y A;  3AB4 A;  4I49 A;  3WWM A;  2WE4 A;  3T7B A;  3TVI A;  2W21 A;  3NWY A;  1Z9D A;  3AB2 A;  2BMU A;  2BND A;  3LL5 A;  2X2W A;  3QVH A;  2OGX B;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
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