3C1NA

Crystal structure of allosteric inhibition threonine-sensitive aspartokinase from methanococcus jannaschii with l-threonine
Total Genus 146
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
468
structure length
458
Chain Sequence
TTVMKFGGTSVGSGERIRHVAKIVTKRKKEDDDVVVVVSAMSEVTNALVEISQQALDVRDIAKVGDFIKFIREKHYKAIEEAISEEIKEEVKKIIDSRIEELEKVLIGVAYLGELTPKSRDYILSFGERLSSPILSGAIRDLGEKSIALEGGEAGIITDNNFGSARVKRLEVKERLLPLLKEGIIPVVTGFIGTTEEGYITTLGRGGSDYSAALIGYGLDADIIEIWTDVSGVYTTDPRLVPTARRIPKLSYIEAMELAYFGAKVLHPRTIEPAMEKGIPILVKNTFEPESEGTLITNDMDSIVKAISTIKNVALINIFGAGMVGVSGTAARIFKALGEEEVNVILISQGSSETNISLVVSEEDVDKALKALKREFGDLNNNLIRDVSVDKDVCVISVVGAGMRGAKGIAGKIFTAVSESGANIKMIAQGSSEVNISFVIDEKDLLNCVRKLHEKFIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structural Basis for Allosteric Inhibition of a Threonine-sensitive Aspartokinase.
pubmed doi rcsb
molecule tags Transferase
source organism Methanocaldococcus jannaschii
molecule keywords Probable aspartokinase
total genus 146
structure length 458
sequence length 468
chains with identical sequence B, C, D
ec nomenclature ec 2.7.2.4: Aspartate kinase.
pdb deposition date 2008-01-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01842 ACT ACT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2130.10 Alpha Beta 2-Layer Sandwich VC0802-like VC0802-like 3c1nA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 3c1nA01
2JJXA 2A1FA 2BNFA 3LKKA 3AB4A 3C20A 2J4KA 2V4YA 2VA1A 2BMUA 3D2MA 3D41A 4OLCA 4F6TB 2JI5A 3S6GA 3C1MA 4KZTA 3ZZFA 1ZHVA 3QUNA 4NDQA 3K4OA 2BNDA 1B7BA 1ZVPA 3QVFA 3KZFA 3WWNA 4USJA 2J0WA 3ZZIA 3AAWA 3QVHA 2WE4A 2J4LA 3B8GA 4NDRA 2BNEA 4NDQB 3WWMA 2F06A 4JZ8A 4NDPA 3AB2A 2J4JA 3K4YA 4I49A 3EK6A 3EK5A 2WXBA 4JZ7A 4NDRB 4AB7A 2W21A 2BRIA 2BUFA 4Q1TA 3ZZHA 2R98A 4NDPB 1OHBA 3T7BA 1E19A 1OH9A 2R8VA 2J5TA 3LL5A 1GSJA 2X2WA 4NDOA 3S6KA 2RD5A 3C1NA 1GS5A 2WE5A 4AXSA 2JJ4A 1OHAA 4JZ9A 3U6UA 2AP9A 3D40A 3L86A 2OGXA 4A7WA 4A7XA 1YBDA 2J0XA 4F6TA 3K52A 3ZZGA 3S6HA 3QURA 3TVIA 3NWYA 2AKOA 3K56A 2OGXB 3D2PA 2J5VA 2HMFA 2V5HA 3QUOA 3LL9A 2CDQA 3L76A 2IJ9A 2E9YA 1Z9DA 2BRXA 4NDOB 2BTYA
chains in the Genus database with same CATH superfamily
2JJXA 2A1FA 2BNFA 3LDGA 3LKKA 3AB4A 3C20A 2J4KA 2V4YA 2VA1A 2BMUA 3D2MA 3D41A 4OLCA 4F6TB 2JI5A 3S6GA 3C1MA 3V8VA 3K0BA 4KZTA 3ZZFA 1ZHVA 3QUNA 4NDQA 3K4OA 2BNDA 1B7BA 1ZVPA 3QVFA 3KZFA 3LDUA 3WWNA 4USJA 2J0WA 3ZZIA 3AAWA 3QVHA 2WE4A 2J4LA 3B8GA 4NDRA 2BNEA 4NDQB 3WWMA 2F06A 4JZ8A 4NDPA 3AB2A 2J4JA 3K4YA 3V97A 4I49A 3EK6A 3EK5A 2WXBA 4JZ7A 4NDRB 4AB7A 2W21A 2BRIA 2BUFA 4Q1TA 3ZZHA 2R98A 4NDPB 1OHBA 3T7BA 1E19A 1OH9A 2R8VA 2J5TA 3LL5A 1GSJA 2X2WA 3TM4A 4NDOA 3S6KA 3TM5A 2RD5A 3C1NA 1GS5A 3TLJA 2WE5A 4AXSA 2JJ4A 1OHAA 4JZ9A 3U6UA 2AP9A 3D40A 3L86A 2OGXA 4A7WA 4A7XA 1YBDA 2J0XA 2C5SA 4KR9A 3TMAA 4F6TA 3K52A 3ZZGA 3S6HA 3QURA 3TVIA 3NWYA 2AKOA 3K56A 2OGXB 3D2PA 2J5VA 2HMFA 4KR6A 2V5HA 3QUOA 3LL9A 2CDQA 3L76A 4KR7A 2IJ9A 2E9YA 1Z9DA 2BRXA 4NDOB 2BTYA
chains in the Genus database with same CATH topology
2JJXA 2A1FA 2BNFA 3LDGA 3LKKA 3AB4A 3C20A 2J4KA 2V4YA 2VA1A 2BMUA 3D2MA 3D41A 4OLCA 4F6TB 2JI5A 3S6GA 3C1MA 3V8VA 3K0BA 4KZTA 3ZZFA 1ZHVA 3QUNA 4NDQA 3K4OA 2BNDA 1B7BA 1ZVPA 3QVFA 3KZFA 3LDUA 3WWNA 4USJA 2J0WA 3ZZIA 3AAWA 3QVHA 2WE4A 2J4LA 3B8GA 4NDRA 2BNEA 4NDQB 3WWMA 2F06A 4JZ8A 4NDPA 3AB2A 2J4JA 3K4YA 3V97A 4I49A 3EK6A 3EK5A 2WXBA 4JZ7A 4NDRB 4AB7A 2W21A 2BRIA 2BUFA 4Q1TA 3ZZHA 2R98A 4NDPB 1OHBA 3T7BA 1E19A 1OH9A 2R8VA 2J5TA 3LL5A 1GSJA 2X2WA 3TM4A 4NDOA 3S6KA 3TM5A 2RD5A 3C1NA 1GS5A 3TLJA 2WE5A 4AXSA 2JJ4A 1OHAA 4JZ9A 3U6UA 2AP9A 3D40A 3L86A 2OGXA 4A7WA 4A7XA 1YBDA 2J0XA 2C5SA 4KR9A 3TMAA 4F6TA 3K52A 3ZZGA 3S6HA 3QURA 3TVIA 3NWYA 2AKOA 3K56A 2OGXB 3D2PA 2J5VA 2HMFA 4KR6A 2V5HA 3QUOA 3LL9A 2CDQA 3L76A 4KR7A 2IJ9A 2E9YA 1Z9DA 2BRXA 4NDOB 2BTYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JJX A;  2A1F A;  2BNF A;  3LKK A;  3AB4 A;  3C20 A;  2J4K A;  2V4Y A;  2VA1 A;  2BMU A;  3D2M A;  3D41 A;  4OLC A;  4F6T B;  2JI5 A;  3S6G A;  3C1M A;  4KZT A;  3ZZF A;  1ZHV A;  3QUN A;  4NDQ A;  3K4O A;  2BND A;  1B7B A;  1ZVP A;  3QVF A;  3KZF A;  3WWN A;  4USJ A;  2J0W A;  3ZZI A;  3AAW A;  3QVH A;  2WE4 A;  2J4L A;  3B8G A;  4NDR A;  2BNE A;  4NDQ B;  3WWM A;  2F06 A;  4JZ8 A;  4NDP A;  3AB2 A;  2J4J A;  3K4Y A;  4I49 A;  3EK6 A;  3EK5 A;  2WXB A;  4JZ7 A;  4NDR B;  4AB7 A;  2W21 A;  2BRI A;  2BUF A;  4Q1T A;  3ZZH A;  2R98 A;  4NDP B;  1OHB A;  3T7B A;  1E19 A;  1OH9 A;  2R8V A;  2J5T A;  3LL5 A;  1GSJ A;  2X2W A;  4NDO A;  3S6K A;  2RD5 A;  3C1N A;  1GS5 A;  2WE5 A;  4AXS A;  2JJ4 A;  1OHA A;  4JZ9 A;  3U6U A;  2AP9 A;  3D40 A;  3L86 A;  2OGX A;  4A7W A;  4A7X A;  1YBD A;  2J0X A;  4F6T A;  3K52 A;  3ZZG A;  3S6H A;  3QUR A;  3TVI A;  3NWY A;  2AKO A;  3K56 A;  2OGX B;  3D2P A;  2J5V A;  2HMF A;  2V5H A;  3QUO A;  3LL9 A;  2CDQ A;  3L76 A;  2IJ9 A;  2E9Y A;  1Z9D A;  2BRX A;  4NDO B;  2BTY A; 
#chains in the Genus database with same CATH topology
 2JJX A;  2A1F A;  2BNF A;  3LDG A;  3LKK A;  3AB4 A;  3C20 A;  2J4K A;  2V4Y A;  2VA1 A;  2BMU A;  3D2M A;  3D41 A;  4OLC A;  4F6T B;  2JI5 A;  3S6G A;  3C1M A;  3V8V A;  3K0B A;  4KZT A;  3ZZF A;  1ZHV A;  3QUN A;  4NDQ A;  3K4O A;  2BND A;  1B7B A;  1ZVP A;  3QVF A;  3KZF A;  3LDU A;  3WWN A;  4USJ A;  2J0W A;  3ZZI A;  3AAW A;  3QVH A;  2WE4 A;  2J4L A;  3B8G A;  4NDR A;  2BNE A;  4NDQ B;  3WWM A;  2F06 A;  4JZ8 A;  4NDP A;  3AB2 A;  2J4J A;  3K4Y A;  3V97 A;  4I49 A;  3EK6 A;  3EK5 A;  2WXB A;  4JZ7 A;  4NDR B;  4AB7 A;  2W21 A;  2BRI A;  2BUF A;  4Q1T A;  3ZZH A;  2R98 A;  4NDP B;  1OHB A;  3T7B A;  1E19 A;  1OH9 A;  2R8V A;  2J5T A;  3LL5 A;  1GSJ A;  2X2W A;  3TM4 A;  4NDO A;  3S6K A;  3TM5 A;  2RD5 A;  3C1N A;  1GS5 A;  3TLJ A;  2WE5 A;  4AXS A;  2JJ4 A;  1OHA A;  4JZ9 A;  3U6U A;  2AP9 A;  3D40 A;  3L86 A;  2OGX A;  4A7W A;  4A7X A;  1YBD A;  2J0X A;  2C5S A;  4KR9 A;  3TMA A;  4F6T A;  3K52 A;  3ZZG A;  3S6H A;  3QUR A;  3TVI A;  3NWY A;  2AKO A;  3K56 A;  2OGX B;  3D2P A;  2J5V A;  2HMF A;  4KR6 A;  2V5H A;  3QUO A;  3LL9 A;  2CDQ A;  3L76 A;  4KR7 A;  2IJ9 A;  2E9Y A;  1Z9D A;  2BRX A;  4NDO B;  2BTY A; 
#chains in the Genus database with same CATH homology
 2JJX A;  2A1F A;  2BNF A;  3LDG A;  3LKK A;  3AB4 A;  3C20 A;  2J4K A;  2V4Y A;  2VA1 A;  2BMU A;  3D2M A;  3D41 A;  4OLC A;  4F6T B;  2JI5 A;  3S6G A;  3C1M A;  3V8V A;  3K0B A;  4KZT A;  3ZZF A;  1ZHV A;  3QUN A;  4NDQ A;  3K4O A;  2BND A;  1B7B A;  1ZVP A;  3QVF A;  3KZF A;  3LDU A;  3WWN A;  4USJ A;  2J0W A;  3ZZI A;  3AAW A;  3QVH A;  2WE4 A;  2J4L A;  3B8G A;  4NDR A;  2BNE A;  4NDQ B;  3WWM A;  2F06 A;  4JZ8 A;  4NDP A;  3AB2 A;  2J4J A;  3K4Y A;  3V97 A;  4I49 A;  3EK6 A;  3EK5 A;  2WXB A;  4JZ7 A;  4NDR B;  4AB7 A;  2W21 A;  2BRI A;  2BUF A;  4Q1T A;  3ZZH A;  2R98 A;  4NDP B;  1OHB A;  3T7B A;  1E19 A;  1OH9 A;  2R8V A;  2J5T A;  3LL5 A;  1GSJ A;  2X2W A;  3TM4 A;  4NDO A;  3S6K A;  3TM5 A;  2RD5 A;  3C1N A;  1GS5 A;  3TLJ A;  2WE5 A;  4AXS A;  2JJ4 A;  1OHA A;  4JZ9 A;  3U6U A;  2AP9 A;  3D40 A;  3L86 A;  2OGX A;  4A7W A;  4A7X A;  1YBD A;  2J0X A;  2C5S A;  4KR9 A;  3TMA A;  4F6T A;  3K52 A;  3ZZG A;  3S6H A;  3QUR A;  3TVI A;  3NWY A;  2AKO A;  3K56 A;  2OGX B;  3D2P A;  2J5V A;  2HMF A;  4KR6 A;  2V5H A;  3QUO A;  3LL9 A;  2CDQ A;  3L76 A;  4KR7 A;  2IJ9 A;  2E9Y A;  1Z9D A;  2BRX A;  4NDO B;  2BTY A; 
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